Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
LibreCat: https://research-explorer.ista.ac.at/record/672
DOI: 10.1016/j.celrep.2017.04.027

Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
LibreCat: https://research-explorer.ista.ac.at/record/674
DOI: 10.1016/j.cub.2017.04.004

The INO80 complex removes A.Z to promote presynaptic filament formation during homologous recombination
C. Lademann, J. Renkawitz, B. Pfander, S. Jentsch, Cell Reports 19 (2017) 1294–1303.
LibreCat: https://research-explorer.ista.ac.at/record/677
DOI: 10.1016/j.celrep.2017.04.051

A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
LibreCat: https://research-explorer.ista.ac.at/record/694
DOI: 10.1242/jcs.200899
PMID: 28515231

Cell migration: Making the waves
J. Müller, M.K. Sixt, Current Biology 27 (2017) –.
LibreCat: https://research-explorer.ista.ac.at/record/1161
DOI: 10.1016/j.cub.2016.11.035
WoS: 000391902500010

Load adaptation of lamellipodial actin networks
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
LibreCat: https://research-explorer.ista.ac.at/record/727
DOI: 10.1016/j.cell.2017.07.051
WoS: 000411331800020

Immunological synapse DC-Tcells
A.F. Leithner, (2017).
LibreCat: https://research-explorer.ista.ac.at/record/5567
DOI: 10.15479/AT:ISTA:71

The dynamic cytokine niche
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
LibreCat: https://research-explorer.ista.ac.at/record/664
DOI: 10.1016/j.immuni.2017.04.006

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
LibreCat: https://research-explorer.ista.ac.at/record/679
DOI: 10.1172/JCI80631
PMID: 28504646

RASGR deficiency causes immunodeficiency with impaired cytoskeletal dynamics
E. Salzer, D. Ça7daf, M. Hons, E. Mace, W. Garncarz, O. Petronczki, R. Platzer, L. Pfajfer, I. Bilic, S. Ban, K. Willmann, M. Mukherjee, V. Supper, H. Hsu, P. Banerjee, P. Sinha, F. Mcclanahan, G. Zlabinger, W. Pickl, J. Gribben, H. Stockinger, K. Bennett, J. Huppa, L. Dupré, Ö. Sanal, U. Jäger, M.K. Sixt, I. Tezcan, J. Orange, K. Boztug, Nature Immunology 17 (2016) 1352–1360.
LibreCat: https://research-explorer.ista.ac.at/record/1137
DOI: 10.1038/ni.3575
PMID: 27776107

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
R. Martins, J. Maier, A. Gorki, K. Huber, O. Sharif, P. Starkl, S. Saluzzo, F. Quattrone, R. Gawish, K. Lakovits, M. Aichinger, B. Radic Sarikas, C. Lardeau, A. Hladik, A. Korosec, M. Brown, K. Vaahtomeri, M. Duggan, D. Kerjaschki, H. Esterbauer, J. Colinge, S. Eisenbarth, T. Decker, K. Bennett, S. Kubicek, M.K. Sixt, G. Superti Furga, S. Knapp, Nature Immunology 17 (2016) 1361–1372.
LibreCat: https://research-explorer.ista.ac.at/record/1142
DOI: 10.1038/ni.3590

A Radical Break Restraining Neutrophil Migration
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
LibreCat: https://research-explorer.ista.ac.at/record/1150
DOI: 10.1016/j.devcel.2016.08.017

A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
LibreCat: https://research-explorer.ista.ac.at/record/1154
DOI: 10.1038/srep36440

Formin’ a nuclear protection
J. Renkawitz, M.K. Sixt, Cell 167 (2016) 1448–1449.
LibreCat: https://research-explorer.ista.ac.at/record/1201
DOI: 10.1016/j.cell.2016.11.024

Efficient T-cell priming and activation requires signaling through prostaglandin  (EP) receptors
V. Sreeramkumar, M. Hons, C. Punzón, J. Stein, D. Sancho, M. Fresno Forcelledo, N. Cuesta, Immunology and Cell Biology 94 (2016) 39–51.
LibreCat: https://research-explorer.ista.ac.at/record/1217
DOI: 10.1038/icb.2015.62

Focal adhesion-independent cell migration
E. Paluch, I. Aspalter, M.K. Sixt, Annual Review of Cell and Developmental Biology 32 (2016) 469–490.
LibreCat: https://research-explorer.ista.ac.at/record/1285
DOI: 10.1146/annurev-cellbio-111315-125341

Intralymphatic CCL21 promotes tissue egress of dendritic cells through afferent lymphatic vessels
E. Russo, A. Teijeira, K. Vaahtomeri, A. Willrodt, J. Bloch, M. Nitschké, L. Santambrogio, D. Kerjaschki, M.K. Sixt, C. Halin, Cell Reports 14 (2016) 1723–1734.
LibreCat: https://research-explorer.ista.ac.at/record/1490
DOI: 10.1016/j.celrep.2016.01.048

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
LibreCat: https://research-explorer.ista.ac.at/record/1599
DOI: 10.1126/science.aad0512
PMID: 26657283

Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
LibreCat: https://research-explorer.ista.ac.at/record/1597
DOI: 10.1016/bs.mie.2015.11.004
PMID: 26921962

Quantitative analysis of haptotactic cell migration
J. Schwarz, Quantitative Analysis of Haptotactic Cell Migration, Institute of Science and Technology Austria, 2016.
LibreCat: https://research-explorer.ista.ac.at/record/1129

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
LibreCat: https://research-explorer.ista.ac.at/record/1321
DOI: 10.1038/ncb3426

Impact of the cell division cycle on gene circuits
V. Bierbaum, S. Klumpp, Physical Biology 12 (2015).
LibreCat: https://research-explorer.ista.ac.at/record/1530
DOI: 10.1088/1478-3975/12/6/066003

Actin flows mediate a universal coupling between cell speed and cell persistence
P. Maiuri, J. Rupprecht, S. Wieser, V. Ruprecht, O. Bénichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.-P.J. Heisenberg, C. Lage Crespo, F. Lautenschlaeger, M. Le Berre, A. Lennon Duménil, M. Raab, H. Thiam, M. Piel, M.K. Sixt, R. Voituriez, Cell 161 (2015) 374–386.
LibreCat: https://research-explorer.ista.ac.at/record/1553
DOI: 10.1016/j.cell.2015.01.056

A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors
K. Heger, M. Kober, D. Rieß, C. Drees, I. de Vries, A. Bertossi, A. Roers, M.K. Sixt, M. Schmidt Supprian, European Journal of Immunology 45 (2015) 1614–1620.
LibreCat: https://research-explorer.ista.ac.at/record/1561
DOI: 10.1002/eji.201545457

The lymph node filter revealed
M. Hons, M.K. Sixt, Nature Immunology 16 (2015) 338–340.
LibreCat: https://research-explorer.ista.ac.at/record/1560
DOI: 10.1038/ni.3126

Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells
M. Chabaud, M. Heuzé, M. Bretou, P. Vargas, P. Maiuri, P. Solanes, M. Maurin, E. Terriac, M. Le Berre, D. Lankar, T. Piolot, R. Adelstein, Y. Zhang, M.K. Sixt, J. Jacobelli, O. Bénichou, R. Voituriez, M. Piel, A. Lennon Duménil, Nature Communications 6 (2015).
LibreCat: https://research-explorer.ista.ac.at/record/1575
DOI: 10.1038/ncomms8526

Editorial overview: Cell adhesion and migration
M.K. Sixt, E. Raz, Current Opinion in Cell Biology 36 (2015) 4–6.
LibreCat: https://research-explorer.ista.ac.at/record/1676
DOI: 10.1016/j.ceb.2015.09.004

Navigating in tissue mazes: Chemoattractant interpretation in complex environments
M. Sarris, M.K. Sixt, Current Opinion in Cell Biology 36 (2015) 93–102.
LibreCat: https://research-explorer.ista.ac.at/record/1687
DOI: 10.1016/j.ceb.2015.08.001

Fragmented communication between immune cells: Neutrophils blaze a trail with migratory cues for T cells to follow to sites of infection
E. Kiermaier, M.K. Sixt, Science 349 (2015) 1055–1056.
LibreCat: https://research-explorer.ista.ac.at/record/1686
DOI: 10.1126/science.aad0867

The serotonin receptor 5-HR regulates the morphology and migratory properties of dendritic cells
K. Holst, D. Guseva, S. Schindler, M.K. Sixt, A. Braun, H. Chopra, O. Pabst, E. Ponimaskin, Journal of Cell Science 128 (2015) 2866–2880.
LibreCat: https://research-explorer.ista.ac.at/record/477
DOI: 10.1242/jcs.167999

Solution structure of CCL19 and identification of overlapping CC and PSGL-1 binding sites
C. Veldkamp, E. Kiermaier, S. Gabel Eissens, M. Gillitzer, D. Lippner, F. Disilvio, C. Mueller, P. Wantuch, G. Chaffee, M. Famiglietti, D. Zgoba, A. Bailey, Y. Bah, S. Engebretson, D. Graupner, E. Lackner, V. Larosa, T. Medeiros, M. Olson, A. Phillips, H. Pyles, A. Richard, S. Schoeller, B. Touzeau, L. Williams, M.K. Sixt, F. Peterson, Biochemistry 54 (2015) 4163–4166.
LibreCat: https://research-explorer.ista.ac.at/record/1618
DOI: 10.1021/acs.biochem.5b00560
PMID: 26115234

Cortical contractility triggers a stochastic switch to fast amoeboid cell motility
V. Ruprecht, S. Wieser, A. Callan Jones, M. Smutny, H. Morita, K. Sako, V. Barone, M. Ritsch Marte, M.K. Sixt, R. Voituriez, C.-P.J. Heisenberg, Cell 160 (2015) 673–685.
LibreCat: https://research-explorer.ista.ac.at/record/1537
DOI: 10.1016/j.cell.2015.01.008

Physiology: Relax and come in
M.K. Sixt, K. Vaahtomeri, Nature 514 (2014) 441–442.
LibreCat: https://research-explorer.ista.ac.at/record/1877
DOI: 10.1038/514441a

Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZE/2
S. Konradi, N. Yasmin, D. Haslwanter, M. Weber, B. Gesslbauer, M.K. Sixt, H. Strobl, European Journal of Immunology 44 (2014) 553–560.
LibreCat: https://research-explorer.ista.ac.at/record/1910
DOI: 10.1002/eji.201343681

A single-molecule approach to explore binding uptake and transport of cancer cell targeting nanotubes
C. Lamprecht, B. Plochberger, V. Ruprecht, S. Wieser, C. Rankl, E. Heister, B. Unterauer, M. Brameshuber, J. Danzberger, P. Lukanov, E. Flahaut, G. Schütz, P. Hinterdorfer, A. Ebner, Nanotechnology 25 (2014).
LibreCat: https://research-explorer.ista.ac.at/record/1925
DOI: 10.1088/0957-4484/25/12/125704

New paradigms in the establishment and maintenance of gradients during directed cell migration
R. Majumdar, M.K. Sixt, C. Parent, Current Opinion in Cell Biology 30 (2014) 33–40.
LibreCat: https://research-explorer.ista.ac.at/record/2158
DOI: 10.1016/j.ceb.2014.05.010
PMID: 24959970

Blood vessels pattern heparan sulfate gradients between their apical and basolateral aspects
L. Stoler Barak, C. Moussion, E. Shezen, M. Hatzav, M.K. Sixt, R. Alon, PLoS One 9 (2014).
LibreCat: https://research-explorer.ista.ac.at/record/2214
DOI: 10.1371/journal.pone.0085699

Mechanisms and principles of homology search during recombination
J. Renkawitz, C. Lademann, S. Jentsch, Nature Reviews Molecular Cell Biology 15 (2014) 369–383.
LibreCat: https://research-explorer.ista.ac.at/record/2215
DOI: 10.1038/nrm3805

A miR-155-dependent microRNA hierarchy in dendritic cell maturation and macrophage activation
A. Dueck, A. Eichner, M.K. Sixt, G. Meister, FEBS Letters 588 (2014) 632–640.
LibreCat: https://research-explorer.ista.ac.at/record/2242
DOI: 10.1016/j.febslet.2014.01.009

A conduit to amplify innate immunity
C. Moussion, M.K. Sixt, Immunity 38 (2013) 853–854.
LibreCat: https://research-explorer.ista.ac.at/record/2830
DOI: 10.1016/j.immuni.2013.05.005

Interstitial dendritic cell guidance by haptotactic chemokine gradients
M. Weber, R. Hauschild, J. Schwarz, C. Moussion, I. de Vries, D. Legler, S. Luther, M.T. Bollenbach, M.K. Sixt, Science 339 (2013) 328–332.
LibreCat: https://research-explorer.ista.ac.at/record/2839
DOI: 10.1126/science.1228456

Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells
E. Fuertbauer, J. Zaujec, P. Uhrin, I. Raab, M. Weber, H. Schachner, M. Bauer, G. Schütz, B. Binder, M.K. Sixt, D. Kerjaschki, H. Stockinger, Immunology Letters 154 (2013) 31–41.
LibreCat: https://research-explorer.ista.ac.at/record/522
DOI: 10.1016/j.imlet.2013.07.007

Live Cell Imaging of Chemotactic Dendritic Cell Migration in Explanted Mouse Ear Preparations
M. Weber, M.K. Sixt, in:, A. Cardona, E. Ubogu (Eds.), Chemokines, Humana Press, Totowa, NJ, 2013, pp. 215–226.
LibreCat: https://research-explorer.ista.ac.at/record/10900
DOI: 10.1007/978-1-62703-426-5_14
PMID: 23625502

MicroRNAs associated with the different human Argonaute proteins
A. Dueck, C. Ziegler, A. Eichner, E. Berezikov, G. Meister, Nucleic Acids Research 40 (2012) 9850–9862.
LibreCat: https://research-explorer.ista.ac.at/record/2946
DOI: 10.1093/nar/gks705

HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes
J. Girard, C. Moussion, R. Förster, Nature Reviews Immunology 12 (2012) 762–773.
LibreCat: https://research-explorer.ista.ac.at/record/2945
DOI: 10.1038/nri3298

NextGen speaks 13 
M. Weber, Science 336 (2012) 32–34.
LibreCat: https://research-explorer.ista.ac.at/record/3167
DOI: 10.1126/science.336.6077.32
PMID: 22491839

Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo
H. Schachtner, A. Li, D. Stevenson, S. Calaminus, S. Thomas, S. Watson, M.K. Sixt, R. Wedlich Söldner, D. Strathdee, L. Machesky, European Journal of Cell Biology 91 (2012) 923–929.
LibreCat: https://research-explorer.ista.ac.at/record/3158
DOI: 10.1016/j.ejcb.2012.04.002
PMID: 22658956

Cell migration: Fibroblasts find a new way to get ahead
M.K. Sixt, Journal of Cell Biology 197 (2012) 347–349.
LibreCat: https://research-explorer.ista.ac.at/record/506
DOI: 10.1083/jcb.201204039

What can we learn from single molecule trajectories?
V. Ruprecht, M. Axmann, S. Wieser, G. Schuetz, Current Protein &; Peptide Science 12 (2011) 714–724.
LibreCat: https://research-explorer.ista.ac.at/record/3287
DOI: 10.2174/138920311798841753

Cells on the move in Philadelphia
M.K. Sixt, C. Parent, Molecular Biology and Evolution 22 (2011) 724.
LibreCat: https://research-explorer.ista.ac.at/record/3371
DOI: 10.1091/mbc.E10-12-0958

In vitro analysis of chemotactic leukocyte migration in 3D environments
M.K. Sixt, T. Lämmermann, Cell Migration 769 (2011) 149–165.
LibreCat: https://research-explorer.ista.ac.at/record/3505
DOI: 10.1007/978-1-61779-207-6_11

Interstitial locomotion of leukocytes
M.K. Sixt, Immunology Letters 138 (2011) 32–34.
LibreCat: https://research-explorer.ista.ac.at/record/3385
DOI: 10.1016/j.imlet.2011.02.013

Setting the clock for recirculating lymphocytes
A. Eichner, M.K. Sixt, Science Signaling 4 (2011).
LibreCat: https://research-explorer.ista.ac.at/record/491
DOI: 10.1126/scisignal.2002617

CAMT is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells
D. Schraivogel, L. Weinmann, D. Beier, G. Tabatabai, A. Eichner, J. Zhu, M. Anton, M.K. Sixt, M. Weller, C. Beier, G. Meister, EMBO Journal 30 (2011) 4309–4322.
LibreCat: https://research-explorer.ista.ac.at/record/518
DOI: 10.1038/emboj.2011.301
PMID: 21857646

The role of chemotactic gradients in dendritic cell migration
K. Schumann, The Role of Chemotactic Gradients in Dendritic Cell Migration, Institute of Science and Technology Austria, 2011.
LibreCat: https://research-explorer.ista.ac.at/record/3275

In vivo analysis of uropod function during physiological T cell trafficking
S. Soriano, M. Hons, K. Schumann, V. Kumar, T. Dennier, R. Lyck, M.K. Sixt, J. Stein, Journal of Immunology 187 (2011) 2356–2364.
LibreCat: https://research-explorer.ista.ac.at/record/3392
DOI: 10.4049/jimmunol.1100935