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Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dn
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Large neutral amino acid levels tune perinatal neuronal excitability and survival
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Quantifying heterologous gene expression during ectopic MazF production in Escherichia coli
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Eukaryotic gene regulation at equilibrium, or non?
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DNA methylation dynamics during germline development
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Altering the properties of spiropyran switches using coordination cages with different symmetries
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Encapsulation within a coordination cage modulates the reactivity of redox-active dyes
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Electron catalysis expands the supramolecular chemist’s toolbox
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Ternary host-guest complexes with rapid exchange kinetics and photoswitchable fluorescence
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Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks
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Heterogeneity of the GFP fitness landscape and data-driven protein design
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Relation between the number of peaks and the number of reciprocal sign epistatic interactions
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Inversions and parallel evolution
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A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory
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The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
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Specification of female germline by microRNA orchestrated auxin signaling in Arabidopsis
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Polygenic adaptation after a sudden change in environment
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On the nanoscale structural evolution of solid discharge products in lithium-sulfur batteries using operando scattering
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Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
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Muskelin regulates actin-dependent synaptic changes and intrinsic brain activity relevant to behavioral and cognitive processes
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A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
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Growthmediated negative feedback shapes quantitative antibiotic response
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Fast, high-throughput production of improved rabies viral vectors for specific, efficient and versatile transsynaptic retrograde labeling
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Specific N-glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning
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Nitrate availability controls translocation of the transcription factor N for cell-type-specific reprogramming of root growth
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Threshold potentials for fast kinetics during mediated redox catalysis of insulators in Li–O2 and Li–S batteries
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Assessing human iPSC-derived microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assay
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In vitro reconstitution of Escherichia coli divisome activation
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The response of a metapopulation to a changing environment
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Evolutionary and structural constraints influencing apolipoprotein AI amyloid behavior
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CH haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories
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Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain
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Health and sustainability of glaciers in High Mountain Asia
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Morphology control in crystalline nanoparticle–polymer aggregates
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Dissipative self-assembly: Fueling with chemicals versus light
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Two linked loci under mutation-selection balance and Muller’s ratchet
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Structure of the mature Rous sarcoma virus lattice reveals a role for I in the formation of the capsid hexamer
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Structural basis for inhibition of the AAA-ATPase Dr by diazaborine
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Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses
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PH regulates neuronal gene expression through the Pol II CTD reader domain SPOC
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Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GI/mTOR assembly
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Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster
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Dissecting organismal morphogenesis by bridging genetics and biophysics
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Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
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Reading the chromatinized genome
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Incomplete removal of extracellular glutamate controls synaptic transmission and integration at a cerebellar synapse
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Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
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An ESCRT-III polymerization sequence drives membrane deformation and fission
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Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease
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Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome
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Nu regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling
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The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments
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Modulating the optical properties of BODIPY dyes by noncovalent dimerization within a flexible coordination cage
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Improving fatigue resistance of dihydropyrene by encapsulation within a coordination cage
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Molecular factors controlling the isomerization of Azobenzenes in the cavity of a flexible coordination cage
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Converting microwave and telecom photons with a silicon photonic nanomechanical interface
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Oncogenic state and cell identity combinatorially dictate the susceptibility of cells within glioma development hierarchy to IGR targeting
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Persistent and reversible solid iodine electrodeposition in nanoporous carbons
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Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
L. Schulte, J. Mao, J. Reitz, S. Sreeramulu, D. Kudlinzki, V.-V. Hodirnau, J. Meier-Credo, K. Saxena, F. Buhr, J.D. Langer, M. Blackledge, A.S. Frangakis, C. Glaubitz, H. Schwalbe, Nature Communications 11 (2020).
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Cryo-electron tomography structure of Ar/3 complex in cells reveals new insights into the branch junction
F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, W. Wan, F.K. Schur, Nature Communications 11 (2020).
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SCIM: Universal single-cell matching with unpaired feature sets
S.G. Stark, J. Ficek, F. Locatello, X. Bonilla, S. Chevrier, F. Singer, R. Aebersold, F.S. Al-Quaddoomi, J. Albinus, I. Alborelli, S. Andani, P.-O. Attinger, M. Bacac, D. Baumhoer, B. Beck-Schimmer, N. Beerenwinkel, C. Beisel, L. Bernasconi, A. Bertolini, B. Bodenmiller, X. Bonilla, R. Casanova, S. Chevrier, N. Chicherova, M. D’Costa, E. Danenberg, N. Davidson, M.-A.D. gan, R. Dummer, S. Engler, M. Erkens, K. Eschbach, C. Esposito, A. Fedier, P. Ferreira, J. Ficek, A.L. Frei, B. Frey, S. Goetze, L. Grob, G. Gut, D. Günther, M. Haberecker, P. Haeuptle, V. Heinzelmann-Schwarz, S. Herter, R. Holtackers, T. Huesser, A. Irmisch, F. Jacob, A. Jacobs, T.M. Jaeger, K. Jahn, A.R. James, P.M. Jermann, A. Kahles, A. Kahraman, V.H. Koelzer, W. Kuebler, J. Kuipers, C.P. Kunze, C. Kurzeder, K.-V. Lehmann, M. Levesque, S. Lugert, G. Maass, M. Manz, P. Markolin, J. Mena, U. Menzel, J.M. Metzler, N. Miglino, E.S. Milani, H. Moch, S. Muenst, R. Murri, C.K. Ng, S. Nicolet, M. Nowak, P.G. Pedrioli, L. Pelkmans, S. Piscuoglio, M. Prummer, M. Ritter, C. Rommel, M.L. Rosano-González, G. Rätsch, N. Santacroce, J.S. del Castillo, R. Schlenker, P.C. Schwalie, S. Schwan, T. Schär, G. Senti, F. Singer, S. Sivapatham, B. Snijder, B. Sobottka, V.T. Sreedharan, S. Stark, D.J. Stekhoven, A.P. Theocharides, T.M. Thomas, M. Tolnay, V. Tosevski, N.C. Toussaint, M.A. Tuncel, M. Tusup, A.V. Drogen, M. Vetter, T. Vlajnic, S. Weber, W.P. Weber, R. Wegmann, M. Weller, F. Wendt, N. Wey, A. Wicki, B. Wollscheid, S. Yu, J. Ziegler, M. Zimmermann, M. Zoche, G. Zuend, G. Rätsch, K.-V. Lehmann, Bioinformatics 36 (2020) i919–i927.
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Geometry and physics of Higgs bundles
L. Anderson, T. Hausel, R. Mazzeo, L. Schaposnik, Oberwolfach Reports 16 (2020) 1357–1417.
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Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing
J.L. Fribourgh, A. Srivastava, C.R. Sandate, A.K. Michael, P.L. Hsu, C. Rakers, L.T. Nguyen, M.R. Torgrimson, G.C.G. Parico, S. Tripathi, N. Zheng, G.C. Lander, T. Hirota, F. Tama, C.L. Partch, ELife 9 (2020).
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Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex
D.F. Gauto, L.F. Estrozi, C.D. Schwieters, G. Effantin, P. Macek, R. Sounier, A.C. Sivertsen, E. Schmidt, R. Kerfah, G. Mas, J.-P. Colletier, P. Güntert, A. Favier, G. Schoehn, P. Schanda, J. Boisbouvier, Nature Communications 10 (2019).
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Mechanistic insights into microsecond time-scale motion of solid proteins using complementary 15N and 1H relaxation dispersion techniques
P. Rovó, C.A. Smith, D. Gauto, B.L. de Groot, P. Schanda, R. Linser, Journal of the American Chemical Society 141 (2019) 858–869.
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Relaxing with liquids and solids – A perspective on biomolecular dynamics
P. Schanda, Journal of Magnetic Resonance 306 (2019) 180–186.
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Activity-controlled annealing of colloidal monolayers
S. Ramananarivo, E. Ducrot, J.A. Palacci, Nature Communications 10 (2019).
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Aromatic ring dynamics, thermal activation, and transient conformations of a 468 kDa enzyme by specific 1H–13C labeling and fast magic-angle spinning NMR
D.F. Gauto, P. Macek, A. Barducci, H. Fraga, A. Hessel, T. Terauchi, D. Gajan, Y. Miyanoiri, J. Boisbouvier, R. Lichtenecker, M. Kainosho, P. Schanda, Journal of the American Chemical Society 141 (2019) 11183–11195.
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Design on a rational basis of high-affinity peptides inhibiting the histone chaperone AS
M.M. Bakail, A. Gaubert, J. Andreani, G. Moal, G. Pinna, E. Boyarchuk, M.-C. Gaillard, R. Courbeyrette, C. Mann, J.-Y. Thuret, B. Guichard, B. Murciano, N. Richet, A. Poitou, C. Frederic, M.-H. Le Du, M. Agez, C. Roelants, Z.A. Gurard-Levin, G. Almouzni, N. Cherradi, R. Guerois, F. Ochsenbein, Cell Chemical Biology 26 (2019) 1573–1585.e10.
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Natural depletion of histone  in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation
S. He, M. Vickers, J. Zhang, X. Feng, ELife 8 (2019).
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Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis
E.J. Lawrence, H. Gao, A.J. Tock, C. Lambing, A.R. Blackwell, X. Feng, I.R. Henderson, Current Biology 29 (2019) 2676–2686.e3.
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Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, ELife 8 (2019).
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Supramolecular control of azobenzene switching on nanoparticles
Z. Chu, Y. Han, T. Bian, S. De, P. Král, R. Klajn, Journal of the American Chemical Society 141 (2019) 1949–1960.
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Diamond grows up
M.J. Biaek, R. Klajn, Chem 5 (2019) 2283–2285.
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The antibiotic cyclomarin blocks arginine-phosphate–induced millisecond dynamics in the N-terminal domain of Clp from Mycobacterium tuberculosis
K. Weinhäupl, M. Brennich, U. Kazmaier, J. Lelievre, L. Ballell, A. Goldberg, P. Schanda, H. Fraga, Journal of Biological Chemistry 293 (2018) 8379–8393.
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Solid state NMR studies of intact lipopolysaccharide endotoxin
C. Laguri, A. Silipo, A.M. Martorana, P. Schanda, R. Marchetti, A. Polissi, A. Molinaro, J.-P. Simorre, ACS Chemical Biology 13 (2018) 2106–2113.
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Structural basis of membrane protein chaperoning through the mitochondrial intermembrane space
K. Weinhäupl, C. Lindau, A. Hessel, Y. Wang, C. Schütze, T. Jores, L. Melchionda, B. Schönfisch, H. Kalbacher, B. Bersch, D. Rapaport, M. Brennich, K. Lindorff-Larsen, N. Wiedemann, P. Schanda, Cell 175 (2018) 1365–1379.e25.
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Reversible chromism of spiropyran in the cavity of a flexible coordination cage
D. Samanta, D. Galaktionova, J. Gemen, L.J.W. Shimon, Y. Diskin-Posner, L. Avram, P. Král, R. Klajn, Nature Communications 9 (2018).
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Significance of whole-genome duplications on the emergence of evolutionary novelties
M. Yuuta, K. Koshiba-Takeuchi, Briefings in Functional Genomics 17 (2018) 329–338.
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Structure and mechanism of the two-component ;1-helical pore-forming toxin YaxAB
B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).
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Mechanical force induces mitochondrial fission
S.C.J. Helle, Q. Feng, M.J. Aebersold, L. Hirt, R.R. Grüter, A. Vahid, A. Sirianni, S. Mostowy, J.G. Snedeker, A. Sari, T. Idema, T. Zambelli, B. Kornmann, ELife 6 (2017).
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Nucleolar expansion and elevated protein translation in premature aging
A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).
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Optimized fast mixing device for real-time NMR applications
R. Franco, A. Favier, P. Schanda, B. Brutscher, Journal of Magnetic Resonance 281 (2017) 125–129.
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Out-of-equilibrium aggregates and coatings during seeded growth of metallic nanoparticles
M. Sawczyk, R. Klajn, Journal of the American Chemical Society 139 (2017) 17973–17978.
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Dynamics of valence-shell electrons and nuclei probed by strong-field holography and rescattering
S.G. Walt, N. Bhargava Ram, M. Atala, N.I. Shvetsov-Shilovski, A. von Conta, D.R. Baykusheva, M. Lein, H.J. Wörner, Nature Communications 8 (2017).
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Animal cryptochromes: Divergent roles in light perception, circadian timekeeping and beyond
A.K. Michael, J.L. Fribourgh, R.N. Van Gelder, C.L. Partch, Photochemistry and Photobiology 93 (2017) 128–140.
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Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms
J.C. Fong, A. Rogers, A.K. Michael, N.C. Parsley, W.-C. Cornell, Y.-C. Lin, P.K. Singh, R. Hartmann, K. Drescher, E. Vinogradov, L.E. Dietrich, C.L. Partch, F.H. Yildiz, ELife 6 (2017).
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0-catenin prevents multinucleation through control of MKL-dependent RhoA activity during cytokinesis
R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong, K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M. Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).
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Linking micronuclei to chromosome fragmentation
E.M. Hatch, M. Hetzer, Cell 161 (2015) 1502–1504.
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Chromothripsis
E.M. Hatch, M. Hetzer, Current Biology 25 (2015) -9.
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Observing the overall rocking motion of a protein in a crystal
P. Ma, Y. Xue, N. Coquelle, J.D. Haller, T. Yuwen, I. Ayala, O. Mikhailovskii, D. Willbold, J.-P. Colletier, N.R. Skrynnikov, P. Schanda, Nature Communications 6 (2015).
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Observation of laser-induced electronic structure in oriented polyatomic molecules
P.M. Kraus, O.I. Tolstikhin, D.R. Baykusheva, A. Rupenyan, J. Schneider, C.Z. Bisgaard, T. Morishita, F. Jensen, L.B. Madsen, H.J. Wörner, Nature Communications 6 (2015).
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Cytosolic BMAL1 moonlights as a translation factor
A.K. Michael, H. Asimgil, C.L. Partch, Trends in Biochemical Sciences 40 (2015) 489–490.
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Nuclear pores set the speed limit for mitosis
A. Buchwalter, M. Hetzer, Cell 156 (2014) 868–869.
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Relax: The analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data
S. Morin, T.E. Linnet, M. Lescanne, P. Schanda, G.S. Thompson, M. Tollinger, K. Teilum, S. Gagné, D. Marion, C. Griesinger, M. Blackledge, E.J. d’Auvergne, Bioinformatics 30 (2014) 2219–2220.
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Nanoporous frameworks exhibiting multiple stimuli responsiveness
P.K. Kundu, G.L. Olsen, V. Kiss, R. Klajn, Nature Communications 5 (2014).
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Cyclic kinetics during thermal equilibration of an axially chiral bis-spiropyran
P.K. Kundu, A. Lerner, K. Kudanda, G. Leitus, R. Klajn, Journal of the American Chemical Society 136 (2014) 11276–11279.
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Support curvature and conformational freedom control chemical reactivity of immobilized species
T. Zdobinsky, P. Sankar Maiti, R. Klajn, Journal of the American Chemical Society 136 (2014) 2711–2714.
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Identification of long-lived proteins reveals exceptional stability of essential cellular structures
B.H. Toyama, J.N. Savas, S.K. Park, M.S. Harris, N.T. Ingolia, J.R. Yates, M. Hetzer, Cell 154 (2013) 971–982.
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