SCA drives the compositional diversity of mammalian respirasomes
I. Vercellino, L.A. Sazanov, Nature Structural and Molecular Biology (2024).

From the 'black box' to 'domino effect' mechanism: What have we learned from the structures of respiratory complex I
L.A. Sazanov, The Biochemical Journal 480 (2023) 319–333.

The Yc accessory factor occupies the site of the oxygen-evolving manganese cluster during photosystem II biogenesis
Z. Zhao, I. Vercellino, J. Knoppová, R. Sobotka, J.W. Murray, P.J. Nixon, L.A. Sazanov, J. Komenda, Nature Communications 14 (2023).

The assembly, regulation and function of the mitochondrial respiratory chain
I. Vercellino, L.A. Sazanov, Nature Reviews Molecular Cell Biology 23 (2022) 141–161.

Structure of respiratory complex I – An emerging blueprint for the mechanism
D. Kampjut, L.A. Sazanov, Current Opinion in Structural Biology 74 (2022).

Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUF subunit
D. Molina-Granada, E. González-Vioque, M.G. Dibley, R. Cabrera-Pérez, A. Vallbona-Garcia, J. Torres-Torronteras, L.A. Sazanov, M.T. Ryan, Y. Cámara, R. Martí, Communications Biology 5 (2022).

A universal coupling mechanism of respiratory complex I
V. Kravchuk, O. Petrova, D. Kampjut, A. Wojciechowska-Bason, Z. Breese, L.A. Sazanov, Nature 609 (2022) 808–814.

Naphthylphthalamic acid associates with and inhibits PIN auxin transporters
L. Abas, M. Kolb, J. Stadlmann, D.P. Janacek, K. Lukic, C. Schwechheimer, L.A. Sazanov, L. Mach, J. Friml, U.Z. Hammes, PNAS 118 (2021).

Cryo-EM grid optimization for membrane proteins
D. Kampjut, J. Steiner, L.A. Sazanov, IScience 24 (2021).

Structure and assembly of the mammalian mitochondrial supercomplex CIII<sub>2</sub>CIV
I. Vercellino, L.A. Sazanov, Nature 598 (2021) 364–367.

NDUF deletion triggers loss of NDUF in Nduf/ mice and Leigh syndrome patients: A stabilizing role for NDUFA
M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).

Charge transfer and chemo-mechanical coupling in respiratory complex I
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, Journal of the American Chemical Society 142 (2020) 9220–9230.

Charge transfer and chemo-mechanical coupling in respiratory complex I
C. Gupta, U. Khaniya, C. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).

Supporting information
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).

Movies
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).

Key role of quinone in the mechanism of respiratory complex I
J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo, D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).

Cryo-EM structure of the entire mammalian F-type ATP synthase
G. Pinke, L. Zhou, L.A. Sazanov, Nature Structural and Molecular Biology 27 (2020) 1077–1085.

The coupling mechanism of mammalian respiratory complex I
D. Kampjut, L.A. Sazanov, Science 370 (2020).

Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
J. Steiner, L.A. Sazanov, ELife 9 (2020).

Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase
L. Zhou, L.A. Sazanov, Science 365 (2019).

Structures of respiratory supercomplex I+II reveal functional and conformational crosstalk
J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular Cell 75 (2019) 1131–1146.e6.

Structure and mechanism of mitochondrial proton-translocating transhydrogenase
D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.

Mammalian mitochondrial complex I structure and disease causing mutations
K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.

Mitochondrial mutations and metabolic adaptation in pancreatic cancer
R. Hardie, E. Van Dam, M. Cowley, T. Han, S. Balaban, M. Pajic, M. Pinese, M. Iconomou, R. Shearer, J. Mckenna, D. Miller, N. Waddell, J. Pearson, S. Grimmond, L.A. Sazanov, A. Biankin, S. Villas Boas, A. Hoy, N. Turner, D. Saunders, Cancer &; Metabolism 5 (2017).

Structure of respiratory complex I: cMinimald bacterial and cde luxed mammalian versions
L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction in Biology , Royal Society of Chemistry, 2017, pp. 25–59.

Clarifying the supercomplex: The higher-order organization of the mitochondrial electron transport chain
J.A. Letts, L.A. Sazanov, Nature Structural and Molecular Biology 24 (2017) 800–808.

Purification of ovine respiratory complex i results in a highly active and stable preparation
J.A. Letts, G. Degliesposti, K. Fiedorczuk, M. Skehel, L.A. Sazanov, Journal of Biological Chemistry 291 (2016) 24657–24675.

Atomic structure of the entire mammalian mitochondrial complex i
K. Fiedorczuk, J.A. Letts, G. Degliesposti, K. Kaszuba, M. Skehel, L.A. Sazanov, Nature 538 (2016) 406–410.

The architecture of respiratory supercomplexes
J.A. Letts, K. Fiedorczuk, L.A. Sazanov, Nature 537 (2016) 644–648.

Reversible FMN dissociation from Escherichia coli respiratory complex I
P. Holt, R. Efremov, E. Nakamaru Ogiso, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 1777–1785.

Structure of bacterial respiratory complex I
J. Berrisford, R. Baradaran, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 892–901.

A giant molecular proton pump: structure and mechanism of respiratory complex I
L.A. Sazanov, Nature Reviews Molecular Cell Biology 16 (2015) 375–388.

Gaining mass: The structure of respiratory complex I-from bacterial towards mitochondrial versions
J.A. Letts, L.A. Sazanov, Current Opinion in Structural Biology 33 (2015) 135–145.

Review and meta-analysis of natural selection in mitochondrial complex I in metazoans
M. Garvin, J. Bielawski, L.A. Sazanov, A. Gharrett, Journal of Zoological Systematics and Evolutionary Research 53 (2014) 1–17.

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation
A. Heikal, Y. Nakatani, E. Dunn, M. Weimar, C. Day, E. Baker, S. Lott, L.A. Sazanov, G. Cook, Molecular Microbiology 91 (2014) 950–964.

The mechanism of coupling between electron transfer and proton translocation in respiratory complex I
L.A. Sazanov, Journal of Bioenergetics and Biomembranes 46 (2014) 247–253.

A long road towards the structure of respiratory complex I, a giant molecular proton pump
L.A. Sazanov, R. Baradaran, R. Efremov, J. Berrisford, G. Minhas, Biochemical Society Transactions 41 (2013) 1265–1271.

Crystal structure of the entire respiratory complex i
R. Baradaran, J. Berrisford, G. Minhas, L.A. Sazanov, Nature 494 (2013) 443–448.

The coupling mechanism of respiratory complex i - A structural and evolutionary perspective
R. Efremov, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1817 (2012) 1785–1795.

Structure of Escherichia coli OmpF porin from lipidic mesophase
R. Efremov, L.A. Sazanov, Journal of Structural Biology 178 (2012) 311–318.

Evolution of respiratory complex I &quot;Supernumerary&quot; subunits are present in the ;1-proteobacterial enzyme
C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, L.A. Sazanov, Journal of Biological Chemistry 286 (2011) 5023–5033.

Structure of the membrane domain of respiratory complex i
R. Efremov, L.A. Sazanov, Nature 476 (2011) 414–421.

Respiratory complex I: 'steam engine' of the cell?
R. Efremov, L.A. Sazanov, Current Opinion in Structural Biology 21 (2011) 532–540.

The architecture of respiratory complex I
R. Efremov, R. Baradaran, L.A. Sazanov, Nature 465 (2010) 441–445.

Structural basis for the mechanism of respiratory complex I
J. Berrisford, L.A. Sazanov, Journal of Biological Chemistry 284 (2009) 29773–29783.

Chemical and NADH-induced, ROS-dependent, cross-linking between sublimits of complex I from Escherichia coli and Thermus thermophilus
J. Berrisford, C. Thompson, L.A. Sazanov, Biochemistry 47 (2008) 10262–10270.

Three-dimensional structure of respiratory complex I from Escherichia coli in ice in the presence of nucleotides
D. Morgan, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1777 (2008) 711–718.

Projection structure of the membrane domain of Escherichia coli respiratory Complex I at 8 Å resolution
E. Baranova, P. Holt, L.A. Sazanov, Journal of Molecular Biology 366 (2007) 140–154.

Single particle analysis confirms distal location of subunits NuoL and NuoM in Escherichia coli complex I
E. Baranova, D. Morgan, L.A. Sazanov, Journal of Structural Biology 159 (2007) 238–242.

Respiratory complex I: Mechanistic and structural insights provided by the crystal structure of the hydrophilic domain
L.A. Sazanov, Biochemistry 46 (2007) 2275–2288.

Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
L.A. Sazanov, P. Hinchliffe, Science 311 (2006) 1430–1436.

Identification of a novel subunit of respiratory complex I from Thermus thermophilus
P. Hinchliffe, J. Carroll, L.A. Sazanov, Biochemistry 45 (2006) 4413–4420.

Biochemistry: Organization of iron-sulfur clusters in respiratory complex I
P. Hinchliffe, L.A. Sazanov, Science 309 (2005) 771–774.

Substrate-induced conformational change in bacterial complex I
A. Mamedova, P. Holt, J. Carroll, L.A. Sazanov, Journal of Biological Chemistry 279 (2004) 23830–23836.

The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli Complex I: implications for the mechanism of proton pumping
P. Holt, D. Morgan, L.A. Sazanov, Journal of Biological Chemistry 278 (2003) 43114–43120.

A role for native lipids in the stabilization and two dimensional crystallization of the Escherichia coli NADH ubiquinone oxidoreductase (complex I)
L.A. Sazanov, J. Carroll, P. Holt, L. Toime, I. Fearnley, Journal of Biological Chemistry 278 (2003) 19483–19491.

Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms
L.A. Sazanov, J. Walker, Journal of Molecular Biology 302 (2000) 455–464.

Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme
L.A. Sazanov, S. Peak Chew, I. Fearnley, J. Walker, Biochemistry 39 (2000) 7229–7235.

The plastid ndh genes code for an NADH-specific dehydrogenase: Isolation of a complex I analogue from pea thylakoid membranes
L.A. Sazanov, P. Burrows, P. Nixon, PNAS 95 (1998) 1319–1324.

Identification of a functional respiratory complex in chloroplasts through analysis of tobacco mutants containing disrupted plastid ndh genes
P. Burrows, L.A. Sazanov, Z. Sváb, P. Maliga, P. Nixon, EMBO Journal 17 (1998) 868–876.

The chloroplast Ndh complex mediates the dark reduction of the plastoquinone pool in response to heat stress in tobacco leaves
L.A. Sazanov, P. Burrows, P. Nixon, FEBS Letters 429 (1998) 115–118.

Presence of a large protein complex containing the ndhK gene product and possessing NADH-specific dehydrogenase activity in thylakoid membranes of higher plant chloroplasts
L.A. Sazanov, P. Burrows, P.J. Nixon, in:, Kluwer, 1996, pp. 705–708.

Estimation of the H+/H- ratio of the reaction catalysed by the nicotinamide nucleotide transhydrogenase in chromatophores from over-expressing strains of Rhodospirillum rubrum and in liposomes inlaid with the purified bovine enzyme
T. Bizouarn, L.A. Sazanov, S. Aubourg, J. Jackson, Biochimica et Biophysica Acta - Bioenergetics 1273 (1996) 4–12.

Detection and characterization of a complex I-like NADH-specific dehydrogenase from pea thylakoids
L.A. Sazanov, P. Burrows, P. Nixon, Biochemical Society Transactions 24 (1996) 739–743.

Cyclic reactions catalysed by detergent-dispersed and reconstituted transhydrogenase from beef heart mitochondria; implications for the mechanism of proton translocation
L.A. Sazanov, B. Jackson, Biochimica et Biophysica Acta - Bioenergetics 1231 (1995) 304–312.

Proton translocating transhydrogenase and NAD- and NADP-linked isocitrate dehydrogenases operate in a substrate cycle which contributes to fine regulation of the tricarboxylic acid cycle activity in mitochondria
L.A. Sazanov, J. Jackson, FEBS Letters 344 (1994) 109–116.

Inhibition of the respiratory burst in mouse macrophages by ultra-low doses of an opioid peptide is consistent with a possible adaptation mechanism
A. Efanov, A. Koshkin, L.A. Sazanov, O.I. Borodulina, S. Varfolomeev, S. Za0tsev, FEBS Letters 355 (1994) 114–116.

Activation and inhibition of mitochondrial transhydrogenase by metal ions
L.A. Sazanov, J. Jackson, Biochimica et Biophysica Acta - Bioenergetics 1144 (1993) 225–228.

Possible functions of the NADP-linked isocitrate dehydrogenase and H+ -transhydrogenase in heart mitochondria 
L.A. Sazanov, J. Jackson, Biochemical Society Transactions 21 (1993) 260.

Proton-translocating transhydrogenase in bacteria
J. Jackson, N.P.J. Cotton, R. Williams, T. Bizouarn, M. Hutton, L.A. Sazanov, C. Thomas, Biochemical Society Transactions 21 (1993) 1010–1013.

Effect of superlow doses (10(-18)-10-(-14) M) of biologically active substances: general rules, features, and possible mechanisms
L.A. Sazanov, S. Za0tsev, Biochemistry (Moscow) 57 (1992) 1443–1460.

Respiratory burst inhibition in human neutrophils by ultra-low doses of [D-Al] methionine enkephalinamide
S. Za0tsev, L.A. Sazanov, A. Koshkin, G. Sud’Ina, S. Varfolomeev, FEBS Letters 291 (1991) 84–86.

Mathematical model of photosynthesis regulation accounts for the effects of changes in external conditions and observed oscillations
L.A. Sazanov, V.A. Karavaev, A.K. Kukushkin, Russian Journal of Physical Chemistry B 52 (1988) 3351–3354.