T. Rauschendorfer et al., “Acute and chronic effects of a light-activated FGF receptor in keratinocytes in vitro and in mice,” Life Science Alliance, vol. 4, no. 11. Life Science Alliance, 2021.
LibreCat: https://research-explorer.ista.ac.at/record/10144
DOI: 10.26508/lsa.202101100
PMID: 34548382

Á. Inglés Prieto et al., “Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease,” PLoS genetics, vol. 17, no. 4. Public Library of Science, p. e1009479, 2021.
LibreCat: https://research-explorer.ista.ac.at/record/9363
DOI: 10.1371/journal.pgen.1009479
WoS: 000640606700001

S. Kainrath and H. L. Janovjak, “Design and application of light-regulated receptor tyrosine kinases,” in Photoswitching Proteins, vol. 2173, D. Niopek, Ed. Springer Nature, 2020, pp. 233–246.
LibreCat: https://research-explorer.ista.ac.at/record/8173
DOI: 10.1007/978-1-0716-0755-8_16

C. Henneberger et al., “LTP induction boosts glutamate spillover by driving withdrawal of perisynaptic astroglia,” Neuron, vol. 108, no. 5. Elsevier, p. 9–936., 2020.
LibreCat: https://research-explorer.ista.ac.at/record/8674
DOI: 10.1016/j.neuron.2020.08.030
WoS: 000603428000010
PMID: 32976770

D. Capek, M. Smutny, A. M. Tichy, M. Morri, H. L. Janovjak, and C.-P. J. Heisenberg, “Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration,” eLife, vol. 8. eLife Sciences Publications, 2019.
LibreCat: https://research-explorer.ista.ac.at/record/6025
DOI: 10.7554/eLife.42093
WoS: 000458025300001

A.-M. Tichy, E. J. Gerrard, J. M. D. Legrand, R. M. Hobbs, and H. L. Janovjak, “Engineering strategy and vector library for the rapid generation of modular light-controlled protein–protein interactions,” Journal of Molecular Biology, vol. 431, no. 17. Elsevier, pp. 3046–3055, 2019.
LibreCat: https://research-explorer.ista.ac.at/record/6564
DOI: 10.1016/j.jmb.2019.05.033
WoS: 000482872100002

C. Mckenzie et al., “Isolation of synaptic vesicles from genetically engineered cultured neurons,” Journal of Neuroscience Methods, vol. 312. Elsevier, pp. 114–121, 2019.
LibreCat: https://research-explorer.ista.ac.at/record/7406
DOI: 10.1016/j.jneumeth.2018.11.018
WoS: 000456220900013
PMID: 30496761

W. Zhang et al., “Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS,” Nature Chemical Biology, vol. 14, no. 9. Nature Publishing Group, pp. 861–869, 2018.
LibreCat: https://research-explorer.ista.ac.at/record/137
DOI: 10.1038/s41589-018-0108-2
WoS: 000442174500013
PMID: 30061718 

M. Morri et al., “Optical functionalization of human class A orphan G-protein-coupled receptors,” Nature Communications, vol. 9, no. 1. Springer Nature, 2018.
LibreCat: https://research-explorer.ista.ac.at/record/5984
DOI: 10.1038/s41467-018-04342-1
WoS: 000432280000006

S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, and H. L. Janovjak, “Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen,” Angewandte Chemie, vol. 129, no. 16. Wiley, pp. 4679–4682, 2017.
LibreCat: https://research-explorer.ista.ac.at/record/538
DOI: 10.1002/ange.201611998

B. Clifton et al., “Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors,” in Synthetic Protein Switches, vol. 1596, V. Stein, Ed. Springer, 2017, pp. 71–87.
LibreCat: https://research-explorer.ista.ac.at/record/957
DOI: 10.1007/978-1-4939-6940-1_5

J. Mitchell et al., “Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment,” in Synthetic Protein Switches, vol. 1596, V. Stein, Ed. Springer, 2017, pp. 89–99.
LibreCat: https://research-explorer.ista.ac.at/record/958
DOI: 10.1007/978-1-4939-6940-1_6

V. Agus and H. L. Janovjak, “Optogenetic methods in drug screening: Technologies and applications,” Current Opinion in Biotechnology, vol. 48. Elsevier, pp. 8–14, 2017.
LibreCat: https://research-explorer.ista.ac.at/record/1026
DOI: 10.1016/j.copbio.2017.02.006
WoS: 000418313200003

S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, and H. L. Janovjak, “Green-light-induced inactivation of receptor signaling using cobalamin-binding domains,” Angewandte Chemie - International Edition, vol. 56, no. 16. Wiley-Blackwell, pp. 4608–4611, 2017.
LibreCat: https://research-explorer.ista.ac.at/record/1028
DOI: 10.1002/anie.201611998
WoS: 000398154000038

H. L. Janovjak, “Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain,” Structure, vol. 24, no. 2. Cell Press, pp. 213–215, 2016.
LibreCat: https://research-explorer.ista.ac.at/record/1440
DOI: 10.1016/j.str.2016.01.002

J. Mitchell et al., “Rangefinder: A semisynthetic FRET sensor design algorithm,” ACS SENSORS, vol. 1, no. 11. American Chemical Society, pp. 1286–1290, 2016.
LibreCat: https://research-explorer.ista.ac.at/record/1101
DOI: 10.1021/acssensors.6b00576

E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, and H. L. Janovjak, “A phytochrome sensory domain permits receptor activation by red light,” Angewandte Chemie - International Edition, vol. 55, no. 21. Wiley, pp. 6339–6342, 2016.
LibreCat: https://research-explorer.ista.ac.at/record/1441
DOI: 10.1002/anie.201601736

K. Sako et al., “Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation,” Cell Reports, vol. 16, no. 3. Cell Press, pp. 866–877, 2016.
LibreCat: https://research-explorer.ista.ac.at/record/1100
DOI: 10.1016/j.celrep.2016.06.036

C. Mckenzie, I. Sanchez-Romero, and H. L. Janovjak, “Flipping the photoswitch: Ion channels under light control,” in Novel chemical tools to study ion channel biology, vol. 869, Springer, 2015, pp. 101–117.
LibreCat: https://research-explorer.ista.ac.at/record/1549
DOI: 10.1007/978-1-4939-2845-3_6

J. Whitfield et al., “Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction,” Protein Science, vol. 24, no. 9. Wiley, pp. 1412–1422, 2015.
LibreCat: https://research-explorer.ista.ac.at/record/1611
DOI: 10.1002/pro.2721
PMID: 26061224

J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, and H. L. Janovjak, “Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection,” Electrophoresis, vol. 36, no. 4. Wiley, pp. 518–525, 2015.
LibreCat: https://research-explorer.ista.ac.at/record/1867
DOI: 10.1002/elps.201400451

Á. Inglés Prieto et al., “Light-assisted small-molecule screening against protein kinases,” Nature Chemical Biology, vol. 11, no. 12. Nature Publishing Group, pp. 952–954, 2015.
LibreCat: https://research-explorer.ista.ac.at/record/1678
DOI: 10.1038/nchembio.1933

Á. Inglés Prieto, E. Gschaider-Reichhart, K. Schelch, H. L. Janovjak, and M. Grusch, “The optogenetic promise for oncology: Episode I,” Molecular and Cellular Oncology, vol. 1, no. 4. Taylor &; Francis, 2014.
LibreCat: https://research-explorer.ista.ac.at/record/2032
DOI: 10.4161/23723548.2014.964045

M. Grusch et al., “Spatio-temporally precise activation of engineered receptor tyrosine kinases by light,” EMBO Journal, vol. 33, no. 15. Wiley-Blackwell, pp. 1713–1726, 2014.
LibreCat: https://research-explorer.ista.ac.at/record/2084
DOI: 10.15252/embj.201387695

S. Szobota, C. Mckenzie, and H. L. Janovjak, “Optical control of ligand-gated ion channels,” Methods in Molecular Biology, vol. 998. Springer, pp. 417–435, 2013.
LibreCat: https://research-explorer.ista.ac.at/record/2857
DOI: 10.1007/978-1-62703-351-0_32

J. Levitz et al., “Optical control of metabotropic glutamate receptors,” Nature Neuroscience, vol. 16. Nature Publishing Group, pp. 507–516, 2013.
LibreCat: https://research-explorer.ista.ac.at/record/2856
DOI: 10.1038/nn.3346
PMID: 23455609

H. L. Janovjak, G. Sandoz, and E. Isacoff, “Modern ionotropic glutamate receptor with a K+ selectivity signature sequence,” Nature Communications, vol. 2, no. 232. Nature Publishing Group, pp. 1–6, 2011.
LibreCat: https://research-explorer.ista.ac.at/record/3405
DOI: 10.1038/ncomms1231

H. L. Janovjak and E. Isacoff, “Structure-based design of light-controlled proteins,” in Photosensitive Molecules for the Control of Biological Function, vol. 55, Springer, 2011, pp. 233–266.
LibreCat: https://research-explorer.ista.ac.at/record/3724
DOI: 10.1007/978-1-61779-031-7_13

H. L. Janovjak, S. Szobota, C. Wyart, D. Trauner, and E. Isacoff, “A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing,” Nature Neuroscience, vol. 13. Nature Publishing Group, pp. 1027–1032, 2010.
LibreCat: https://research-explorer.ista.ac.at/record/3407
DOI: 10.1038/nn.2589

P. Stawski, H. L. Janovjak, and D. Trauner, “Pharmacology of ionotropic glutamate receptors: a structural perspective,” Bioorganic and Medicinal Chemistry, vol. 18, no. 22. Elsevier, pp. 7759–7772, 2010.
LibreCat: https://research-explorer.ista.ac.at/record/3406
DOI: 10.1016/j.bmc.2010.09.012

P. Szymczak and H. L. Janovjak, “Periodic forces trigger a complex mechanical response in ubiquitin,” Journal of Molecular Biology, vol. 390, no. 3. Elsevier, pp. 443–456, 2009.
LibreCat: https://research-explorer.ista.ac.at/record/3408
DOI: 10.1016/j.jmb.2009.04.071

H. L. Janovjak, T. Sapra, A. Kedrov, and D. Mueller, “From valleys to ridges: Exploring the energy landscape of single membrane proteins,” ChemPhysChem, vol. 9, no. 7. Wiley-Blackwell, pp. 954–966, 2008.
LibreCat: https://research-explorer.ista.ac.at/record/3410
DOI: 10.1002/cphc.200700662

J. Struckmeier et al., “Fully automated single-molecule force spectroscopy for screening applications,” Nanotechnology, vol. 19, no. 38. IOP Publishing Ltd., 2008.
LibreCat: https://research-explorer.ista.ac.at/record/3409
DOI: 10.1088/0957-4484/19/38/384020

A. Engel, H. L. Janovjak, D. Fotiadis, A. Kedrov, D. Cisneros, and D. Mueller, “Single-molecule microscopy and force spectroscopy of membrane proteins,” in Single Molecules and Nanotechnology, vol. 12, Springer, 2008, pp. 279–311.
LibreCat: https://research-explorer.ista.ac.at/record/3726
DOI: 10.1007/978-3-540-73924-1_11

J. Preiner et al., “Free energy of membrane protein unfolding derived from single-molecule force measurements,” Biophysical Journal, vol. 93, no. 3. Biophysical Society, pp. 930–937, 2007.
LibreCat: https://research-explorer.ista.ac.at/record/3411
DOI: 10.1529/biophysj.106.096982

A. Kedrov, H. L. Janovjak, T. Sapra, and D. Mueller, “Deciphering molecular interactions of native membrane proteins by single-molecule force spectroscopy,” Annual Review of Biophysics, vol. 36. Annual Reviews, pp. 233–260, 2007.
LibreCat: https://research-explorer.ista.ac.at/record/3412
DOI: 10.1146/annurev.biophys.36.040306.132640

C. Bippes, H. L. Janovjak, A. Kedrov, and D. Mueller, “Digital force-feedback for protein unfolding experiments using atomic force microscopy,” Nanotechnology, vol. 18, no. 4. IOP Publishing Ltd., 2007.
LibreCat: https://research-explorer.ista.ac.at/record/3727
DOI: 10.1088/0957-4484/18/4/044022

H. L. Janovjak, H. Knaus, and D. Mueller, “Transmembrane helices have rough energy surfaces,” Journal of the American Chemical Society, vol. 129, no. 2. ACS, pp. 246–247, 2007.
LibreCat: https://research-explorer.ista.ac.at/record/3723
DOI: 10.1021/ja065684a

H. L. Janovjak, R. Sawhney, M. Stark, and D. Mueller, “Atomic force microscopy,” in Techniques in Microscopy for Biomedical Applications, vol. 2, World Scientific Publishing, 2006, pp. 213–284.
LibreCat: https://research-explorer.ista.ac.at/record/3404

M. Kessler, K. Gottschalk, H. L. Janovjak, D. Mueller, and H. Gaub, “Bacteriorhodopsin folds into the membrane against an external force,” Journal of Molecular Biology, vol. 357, no. 2. Elsevier, pp. 644–654, 2006.
LibreCat: https://research-explorer.ista.ac.at/record/3413
DOI: 10.1016/j.jmb.2005.12.065

A. Kedrov, H. L. Janovjak, C. Ziegler, W. Kühlbrandt, and D. Mueller, “Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli,” Journal of Molecular Biology, vol. 355, no. 1. Elsevier, pp. 2–8, 2006.
LibreCat: https://research-explorer.ista.ac.at/record/3414
DOI: 10.1016/j.jmb.2005.10.028

H. L. Janovjak, A. Kedrov, D. Cisneros, T. Sapra, J. Struckmeier, and D. Mueller, “Imaging and detecting molecular interactions of single membrane proteins,” Neurobiology of Aging, vol. 27. Elsevier, pp. 546–561, 2006.
LibreCat: https://research-explorer.ista.ac.at/record/3415
DOI: 10.1016/j.neurobiolaging.2005.03.031

C. Bippes, A. Humphris, M. Stark, D. Mueller, and H. L. Janovjak, “Direct measurement of single-molecule visco-elasticity in atomic force microscope force-extension experiments,” European Biophysics Journal, vol. 35, no. 3. Springer, pp. 287–292, 2006.
LibreCat: https://research-explorer.ista.ac.at/record/3729
DOI: 10.1007/s00249-005-0023-9

M. Cieplak, S. Filipek, H. L. Janovjak, and K. Krzysko, “Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment,” Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 1758, no. 4. Elsevier, pp. 537–544, 2006.
LibreCat: https://research-explorer.ista.ac.at/record/3728
DOI: 10.1016/j.bbamem.2006.03.028

H. L. Janovjak and D. Mueller, “Rastersondenmikroskopie,” in Bioanalytik, Spektrum Akademischer Verlag, 2006.
LibreCat: https://research-explorer.ista.ac.at/record/3722

M. Kuhn, H. L. Janovjak, M. Hubain, and D. Mueller, “Automated alignment and pattern recognition of single-molecule force spectroscopy data,” Journal of Microscopy, vol. 218, no. 2. Wiley-Blackwell, pp. 125–132, 2005.
LibreCat: https://research-explorer.ista.ac.at/record/3417
DOI: 10.1111/j.1365-2818.2005.01478.x

H. L. Janovjak, T. Sapra, and D. Mueller, “Complex stability of single proteins explored by forced unfolding experiments,” Biophysical Journal, vol. 88, no. 5. Biophysical Society, pp. 37–39, 2005.
LibreCat: https://research-explorer.ista.ac.at/record/3416
DOI: 10.1529/biophysj.105.059774

H. L. Janovjak, J. Struckmeier, and D. Mueller, “Hydrodynamic effects in fast AFM single molecule force measurements,” European Biophysics Journal, vol. 34, no. 1. Springer, pp. 91–96, 2005.
LibreCat: https://research-explorer.ista.ac.at/record/3418
DOI: 10.1007/s00249-004-0430-3

H. L. Janovjak, D. Mueller, and A. Humphris, “Molecular force modulation spectroscopy revealing the dynamic response of single bacteriorhodopsins,” Biophysical Journal, vol. 88, no. 2. Biophysical Society, pp. 1423–1431, 2005.
LibreCat: https://research-explorer.ista.ac.at/record/3721
DOI: 10.1529/biophysj.104.052746

A. Kedrov, C. Ziegler, H. L. Janovjak, W. Kühlbrandt, and D. Mueller, “Controlled unfolding and refolding of a single sodium/proton antiporter using atomic force microscopy,” Journal of Molecular Biology, vol. 340, no. 5. Elsevier, pp. 1143–1152, 2004.
LibreCat: https://research-explorer.ista.ac.at/record/3420
DOI: 10.1016/j.jmb.2004.05.026

H. L. Janovjak, J. Struckmeier, M. Hubain, M. Kessler, A. Kedrov, and D. Mueller, “Probing the energy landscape of the membrane protein bacteriorhodopsin,” Structure, vol. 12, no. 5. Cell Press, pp. 871–879, 2004.
LibreCat: https://research-explorer.ista.ac.at/record/3419
DOI: 10.1016/j.str.2004.03.016

H. L. Janovjak, M. Kessler, D. Oesterhelt, H. Gaub, and D. Mueller, “Unfolding pathways of native bacteriorhodopsin depend on temperature,” EMBO Journal, vol. 22, no. 19. Wiley-Blackwell, pp. 5220–5229, 2003.
LibreCat: https://research-explorer.ista.ac.at/record/3725
DOI: 10.1093/emboj/cdg509

D. Mueller, H. L. Janovjak, T. Lehto, L. Kuerschner, and K. Anderson, “Observing structure, function and assembly of single proteins by AFM,” Progress in Biophysics and Molecular Biology, vol. 79, no. 1–3. Elsevier, pp. 1–43, 2002.
LibreCat: https://research-explorer.ista.ac.at/record/3421
DOI: 10.1016/S0079-6107(02)00009-3
PMID: 12225775

P. Müller, H. L. Janovjak, A. Miserez, and Z. Dobbie, “Processing of gene expression data generated by quantitative real-time RT-PCR,” Biotechniques, vol. 32, no. 6. Informa Healthcare, pp. 1372–1379, 2002.
LibreCat: https://research-explorer.ista.ac.at/record/3422
PMID: 12074169