Rauschendorfer T, Gurri S, Heggli I, Maddaluno L, Meyer M, Inglés Prieto Á, Janovjak HL, Werner S. 2021. Acute and chronic effects of a light-activated FGF receptor in keratinocytes in vitro and in mice. Life Science Alliance. 4(11), e202101100.
LibreCat: https://research-explorer.ista.ac.at/record/10144
DOI: 10.26508/lsa.202101100
PMID: 34548382

Inglés Prieto Á, Furthmann N, Crossman SH, Tichy AM, Hoyer N, Petersen M, Zheden V, Bicher J, Gschaider-Reichhart E, György A, Siekhaus DE, Soba P, Winklhofer KF, Janovjak HL. 2021. Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease. PLoS genetics. 17(4), e1009479.
LibreCat: https://research-explorer.ista.ac.at/record/9363
DOI: 10.1371/journal.pgen.1009479
WoS: 000640606700001

Kainrath S, Janovjak HL. 2020.Design and application of light-regulated receptor tyrosine kinases. In: Photoswitching Proteins. Methods in Molecular Biology, vol. 2173, 233–246.
LibreCat: https://research-explorer.ista.ac.at/record/8173
DOI: 10.1007/978-1-0716-0755-8_16

Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, Rama S, Zheng K, Jensen TP, Sanchez-Romero I, Jackson CJ, Janovjak HL, Ottersen OP, Nagelhus EA, Oliet SHR, Stewart MG, Nägerl UVa, Rusakov DA. 2020. LTP induction boosts glutamate spillover by driving withdrawal of perisynaptic astroglia. Neuron. 108(5), 9–936..
LibreCat: https://research-explorer.ista.ac.at/record/8674
DOI: 10.1016/j.neuron.2020.08.030
WoS: 000603428000010
PMID: 32976770

Capek D, Smutny M, Tichy AM, Morri M, Janovjak HL, Heisenberg C-PJ. 2019. Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration. eLife. 8, e42093.
LibreCat: https://research-explorer.ista.ac.at/record/6025
DOI: 10.7554/eLife.42093
WoS: 000458025300001

Tichy A-M, Gerrard EJ, Legrand JMD, Hobbs RM, Janovjak HL. 2019. Engineering strategy and vector library for the rapid generation of modular light-controlled protein–protein interactions. Journal of Molecular Biology. 431(17), 3046–3055.
LibreCat: https://research-explorer.ista.ac.at/record/6564
DOI: 10.1016/j.jmb.2019.05.033
WoS: 000482872100002

Mckenzie C, Spanova M, Johnson AJ, Kainrath S, Zheden V, Sitte HH, Janovjak HL. 2019. Isolation of synaptic vesicles from genetically engineered cultured neurons. Journal of Neuroscience Methods. 312, 114–121.
LibreCat: https://research-explorer.ista.ac.at/record/7406
DOI: 10.1016/j.jneumeth.2018.11.018
WoS: 000456220900013
PMID: 30496761

Zhang W, Herde M, Mitchell J, Whitfield J, Wulff A, Vongsouthi V, Sanchez-Romero I, Gulakova P, Minge D, Breithausen B, Schoch S, Janovjak HL, Jackson C, Henneberger C. 2018. Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS. Nature Chemical Biology. 14(9), 861–869.
LibreCat: https://research-explorer.ista.ac.at/record/137
DOI: 10.1038/s41589-018-0108-2
WoS: 000442174500013
PMID: 30061718 

Morri M, Sanchez-Romero I, Tichy A-M, Kainrath S, Gerrard EJ, Hirschfeld P, Schwarz J, Janovjak HL. 2018. Optical functionalization of human class A orphan G-protein-coupled receptors. Nature Communications. 9(1), 1950.
LibreCat: https://research-explorer.ista.ac.at/record/5984
DOI: 10.1038/s41467-018-04342-1
WoS: 000432280000006

Kainrath S, Stadler M, Gschaider-Reichhart E, Distel M, Janovjak HL. 2017. Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen. Angewandte Chemie. 129(16), 4679–4682.
LibreCat: https://research-explorer.ista.ac.at/record/538
DOI: 10.1002/ange.201611998

Clifton B, Whitfield J, Sanchez-Romero I, Herde M, Henneberger C, Janovjak HL, Jackson C. 2017.Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors. In: Synthetic Protein Switches. Methods in Molecular Biology, vol. 1596, 71–87.
LibreCat: https://research-explorer.ista.ac.at/record/957
DOI: 10.1007/978-1-4939-6940-1_5

Mitchell J, Zhang W, Herde M, Henneberger C, Janovjak HL, O’Mara M, Jackson C. 2017.Method for developing optical sensors using a synthetic dye fluorescent protein FRET pair and computational modeling and assessment. In: Synthetic Protein Switches. Methods in Molecular Biology, vol. 1596, 89–99.
LibreCat: https://research-explorer.ista.ac.at/record/958
DOI: 10.1007/978-1-4939-6940-1_6

Agus V, Janovjak HL. 2017. Optogenetic methods in drug screening: Technologies and applications. Current Opinion in Biotechnology. 48, 8–14.
LibreCat: https://research-explorer.ista.ac.at/record/1026
DOI: 10.1016/j.copbio.2017.02.006
WoS: 000418313200003

Kainrath S, Stadler M, Gschaider-Reichhart E, Distel M, Janovjak HL. 2017. Green-light-induced inactivation of receptor signaling using cobalamin-binding domains. Angewandte Chemie - International Edition. 56(16), 4608–4611.
LibreCat: https://research-explorer.ista.ac.at/record/1028
DOI: 10.1002/anie.201611998
WoS: 000398154000038

Janovjak HL. 2016. Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain. Structure. 24(2), 213–215.
LibreCat: https://research-explorer.ista.ac.at/record/1440
DOI: 10.1016/j.str.2016.01.002

Mitchell J, Whitfield J, Zhang W, Henneberger C, Janovjak HL, O’Mara M, Jackson C. 2016. Rangefinder: A semisynthetic FRET sensor design algorithm. ACS SENSORS. 1(11), 1286–1290.
LibreCat: https://research-explorer.ista.ac.at/record/1101
DOI: 10.1021/acssensors.6b00576

Gschaider-Reichhart E, Inglés Prieto Á, Tichy A-M, Mckenzie C, Janovjak HL. 2016. A phytochrome sensory domain permits receptor activation by red light. Angewandte Chemie - International Edition. 55(21), 6339–6342.
LibreCat: https://research-explorer.ista.ac.at/record/1441
DOI: 10.1002/anie.201601736

Sako K, Pradhan S, Barone V, Inglés Prieto Á, Mueller P, Ruprecht V, Capek D, Galande S, Janovjak HL, Heisenberg C-PJ. 2016. Optogenetic control of nodal signaling reveals a temporal pattern of nodal signaling regulating cell fate specification during gastrulation. Cell Reports. 16(3), 866–877.
LibreCat: https://research-explorer.ista.ac.at/record/1100
DOI: 10.1016/j.celrep.2016.06.036

Mckenzie C, Sanchez-Romero I, Janovjak HL. 2015.Flipping the photoswitch: Ion channels under light control. In: Novel chemical tools to study ion channel biology. vol. 869, 101–117.
LibreCat: https://research-explorer.ista.ac.at/record/1549
DOI: 10.1007/978-1-4939-2845-3_6

Whitfield J, Zhang W, Herde M, Clifton B, Radziejewski J, Janovjak HL, Henneberger C, Jackson C. 2015. Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction. Protein Science. 24(9), 1412–1422.
LibreCat: https://research-explorer.ista.ac.at/record/1611
DOI: 10.1002/pro.2721
PMID: 26061224

Hühner J, Inglés Prieto Á, Neusüß C, Lämmerhofer M, Janovjak HL. 2015. Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection. Electrophoresis. 36(4), 518–525.
LibreCat: https://research-explorer.ista.ac.at/record/1867
DOI: 10.1002/elps.201400451

Inglés Prieto Á, Gschaider-Reichhart E, Muellner M, Nowak M, Nijman S, Grusch M, Janovjak HL. 2015. Light-assisted small-molecule screening against protein kinases. Nature Chemical Biology. 11(12), 952–954.
LibreCat: https://research-explorer.ista.ac.at/record/1678
DOI: 10.1038/nchembio.1933

Inglés Prieto Á, Gschaider-Reichhart E, Schelch K, Janovjak HL, Grusch M. 2014. The optogenetic promise for oncology: Episode I. Molecular and Cellular Oncology. 1(4), e964045.
LibreCat: https://research-explorer.ista.ac.at/record/2032
DOI: 10.4161/23723548.2014.964045

Grusch M, Schelch K, Riedler R, Gschaider-Reichhart E, Differ C, Berger W, Inglés Prieto Á, Janovjak HL. 2014. Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. EMBO Journal. 33(15), 1713–1726.
LibreCat: https://research-explorer.ista.ac.at/record/2084
DOI: 10.15252/embj.201387695

Szobota S, Mckenzie C, Janovjak HL. 2013. Optical control of ligand-gated ion channels. Methods in Molecular Biology. 998, 417–435.
LibreCat: https://research-explorer.ista.ac.at/record/2857
DOI: 10.1007/978-1-62703-351-0_32

Levitz J, Pantoja C, Gaub B, Janovjak HL, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier A, Trauner D, Isacoff E. 2013. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16, 507–516.
LibreCat: https://research-explorer.ista.ac.at/record/2856
DOI: 10.1038/nn.3346
PMID: 23455609

Janovjak HL, Sandoz G, Isacoff E. 2011. Modern ionotropic glutamate receptor with a K+ selectivity signature sequence. Nature Communications. 2(232), 1–6.
LibreCat: https://research-explorer.ista.ac.at/record/3405
DOI: 10.1038/ncomms1231

Janovjak HL, Isacoff E. 2011.Structure-based design of light-controlled proteins. In: Photosensitive Molecules for the Control of Biological Function. vol. 55, 233–266.
LibreCat: https://research-explorer.ista.ac.at/record/3724
DOI: 10.1007/978-1-61779-031-7_13

Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. 2010. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nature Neuroscience. 13, 1027–1032.
LibreCat: https://research-explorer.ista.ac.at/record/3407
DOI: 10.1038/nn.2589

Stawski P, Janovjak HL, Trauner D. 2010. Pharmacology of ionotropic glutamate receptors: a structural perspective. Bioorganic and Medicinal Chemistry. 18(22), 7759–7772.
LibreCat: https://research-explorer.ista.ac.at/record/3406
DOI: 10.1016/j.bmc.2010.09.012

Szymczak P, Janovjak HL. 2009. Periodic forces trigger a complex mechanical response in ubiquitin. Journal of Molecular Biology. 390(3), 443–456.
LibreCat: https://research-explorer.ista.ac.at/record/3408
DOI: 10.1016/j.jmb.2009.04.071

Janovjak HL, Sapra T, Kedrov A, Mueller D. 2008. From valleys to ridges: Exploring the energy landscape of single membrane proteins. ChemPhysChem. 9(7), 954–966.
LibreCat: https://research-explorer.ista.ac.at/record/3410
DOI: 10.1002/cphc.200700662

Struckmeier J, Wahl R, Leuschner M, Nunes J, Janovjak HL, Geisler U, Hofmann G, Jähnke T, Mueller D. 2008. Fully automated single-molecule force spectroscopy for screening applications. Nanotechnology. 19(38).
LibreCat: https://research-explorer.ista.ac.at/record/3409
DOI: 10.1088/0957-4484/19/38/384020

Engel A, Janovjak HL, Fotiadis D, Kedrov A, Cisneros D, Mueller D. 2008.Single-molecule microscopy and force spectroscopy of membrane proteins. In: Single Molecules and Nanotechnology. vol. 12, 279–311.
LibreCat: https://research-explorer.ista.ac.at/record/3726
DOI: 10.1007/978-3-540-73924-1_11

Preiner J, Janovjak HL, Rankl C, Knaus H, Cisneros D, Kedrov A, Kienberger F, Mueller D, Hinterdorfer P. 2007. Free energy of membrane protein unfolding derived from single-molecule force measurements. Biophysical Journal. 93(3), 930–937.
LibreCat: https://research-explorer.ista.ac.at/record/3411
DOI: 10.1529/biophysj.106.096982

Kedrov A, Janovjak HL, Sapra T, Mueller D. 2007. Deciphering molecular interactions of native membrane proteins by single-molecule force spectroscopy. Annual Review of Biophysics. 36, 233–260.
LibreCat: https://research-explorer.ista.ac.at/record/3412
DOI: 10.1146/annurev.biophys.36.040306.132640

Bippes C, Janovjak HL, Kedrov A, Mueller D. 2007. Digital force-feedback for protein unfolding experiments using atomic force microscopy. Nanotechnology. 18(4).
LibreCat: https://research-explorer.ista.ac.at/record/3727
DOI: 10.1088/0957-4484/18/4/044022

Janovjak HL, Knaus H, Mueller D. 2007. Transmembrane helices have rough energy surfaces. Journal of the American Chemical Society. 129(2), 246–247.
LibreCat: https://research-explorer.ista.ac.at/record/3723
DOI: 10.1021/ja065684a

Janovjak HL, Sawhney R, Stark M, Mueller D. 2006.Atomic force microscopy. In: Techniques in Microscopy for Biomedical Applications. Manuals in Biomedical Research, vol. 2, 213–284.
LibreCat: https://research-explorer.ista.ac.at/record/3404

Kessler M, Gottschalk K, Janovjak HL, Mueller D, Gaub H. 2006. Bacteriorhodopsin folds into the membrane against an external force. Journal of Molecular Biology. 357(2), 644–654.
LibreCat: https://research-explorer.ista.ac.at/record/3413
DOI: 10.1016/j.jmb.2005.12.065

Kedrov A, Janovjak HL, Ziegler C, Kühlbrandt W, Mueller D. 2006. Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli. Journal of Molecular Biology. 355(1), 2–8.
LibreCat: https://research-explorer.ista.ac.at/record/3414
DOI: 10.1016/j.jmb.2005.10.028

Janovjak HL, Kedrov A, Cisneros D, Sapra T, Struckmeier J, Mueller D. 2006. Imaging and detecting molecular interactions of single membrane proteins. Neurobiology of Aging. 27, 546–561.
LibreCat: https://research-explorer.ista.ac.at/record/3415
DOI: 10.1016/j.neurobiolaging.2005.03.031

Bippes C, Humphris A, Stark M, Mueller D, Janovjak HL. 2006. Direct measurement of single-molecule visco-elasticity in atomic force microscope force-extension experiments. European Biophysics Journal. 35(3), 287–292.
LibreCat: https://research-explorer.ista.ac.at/record/3729
DOI: 10.1007/s00249-005-0023-9

Cieplak M, Filipek S, Janovjak HL, Krzysko K. 2006. Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1758(4), 537–544.
LibreCat: https://research-explorer.ista.ac.at/record/3728
DOI: 10.1016/j.bbamem.2006.03.028

Janovjak HL, Mueller D. 2006.Rastersondenmikroskopie. In: Bioanalytik. .
LibreCat: https://research-explorer.ista.ac.at/record/3722

Kuhn M, Janovjak HL, Hubain M, Mueller D. 2005. Automated alignment and pattern recognition of single-molecule force spectroscopy data. Journal of Microscopy. 218(2), 125–132.
LibreCat: https://research-explorer.ista.ac.at/record/3417
DOI: 10.1111/j.1365-2818.2005.01478.x

Janovjak HL, Sapra T, Mueller D. 2005. Complex stability of single proteins explored by forced unfolding experiments. Biophysical Journal. 88(5), 37–39.
LibreCat: https://research-explorer.ista.ac.at/record/3416
DOI: 10.1529/biophysj.105.059774

Janovjak HL, Struckmeier J, Mueller D. 2005. Hydrodynamic effects in fast AFM single molecule force measurements. European Biophysics Journal. 34(1), 91–96.
LibreCat: https://research-explorer.ista.ac.at/record/3418
DOI: 10.1007/s00249-004-0430-3

Janovjak HL, Mueller D, Humphris A. 2005. Molecular force modulation spectroscopy revealing the dynamic response of single bacteriorhodopsins. Biophysical Journal. 88(2), 1423–1431.
LibreCat: https://research-explorer.ista.ac.at/record/3721
DOI: 10.1529/biophysj.104.052746

Kedrov A, Ziegler C, Janovjak HL, Kühlbrandt W, Mueller D. 2004. Controlled unfolding and refolding of a single sodium/proton antiporter using atomic force microscopy. Journal of Molecular Biology. 340(5), 1143–1152.
LibreCat: https://research-explorer.ista.ac.at/record/3420
DOI: 10.1016/j.jmb.2004.05.026

Janovjak HL, Struckmeier J, Hubain M, Kessler M, Kedrov A, Mueller D. 2004. Probing the energy landscape of the membrane protein bacteriorhodopsin. Structure. 12(5), 871–879.
LibreCat: https://research-explorer.ista.ac.at/record/3419
DOI: 10.1016/j.str.2004.03.016

Janovjak HL, Kessler M, Oesterhelt D, Gaub H, Mueller D. 2003. Unfolding pathways of native bacteriorhodopsin depend on temperature. EMBO Journal. 22(19), 5220–5229.
LibreCat: https://research-explorer.ista.ac.at/record/3725
DOI: 10.1093/emboj/cdg509

Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. 2002. Observing structure, function and assembly of single proteins by AFM. Progress in Biophysics and Molecular Biology. 79(1–3), 1–43.
LibreCat: https://research-explorer.ista.ac.at/record/3421
DOI: 10.1016/S0079-6107(02)00009-3
PMID: 12225775

Müller P, Janovjak HL, Miserez A, Dobbie Z. 2002. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques. 32(6), 1372–1379.
LibreCat: https://research-explorer.ista.ac.at/record/3422
PMID: 12074169