Koppensteiner P, Bhandari P, Önal C, et al. GABAB receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles. Proceedings of the National Academy of Sciences. 2024;121(8). doi:10.1073/pnas.2301449121

Vandael DH, Jonas PM. Structure, biophysics, and circuit function of a “giant”10.1126/science.adg6757__cortical presynaptic terminal. Science. 2024;383(6687):ead57. doi:10.1126/science.adg6757

Chen J, Kaufmann W, Chen C, et al. Developmental transformation of C+ channel-vesicle nanotopography at a central GABAergic synapse. Neuron. doi:10.1016/j.neuron.2023.12.002

Rothman JS, Borges Merjane C, Holderith N, Jonas PM, Angus Silver R. Validation of a stereological method for estimating particle size and density from 2D projections with high accuracy. PLoS ONE. 2023;18(3 March). doi:10.1371/journal.pone.0277148

Velicky P, Miguel Villalba E, Michalska JM, et al. Dense 4D nanoscale reconstruction of living brain tissue. Nature Methods. 2023;20:1256-1265. doi:10.1038/s41592-023-01936-6

Michalska JM, Lyudchik J, Velicky P, et al. Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. 2023. doi:10.1038/s41587-023-01911-8

Ben Simon Y, Käfer K, Velicky P, Csicsvari JL, Danzl JG, Jonas PM. A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory. Nature Communications. 2022;13. doi:10.1038/s41467-022-32559-8

Sumser AL, Jösch MA, Jonas PM, Ben Simon Y. Fast, high-throughput production of improved rabies viral vectors for specific, efficient and versatile transsynaptic retrograde labeling. eLife. 2022;11. doi:10.7554/elife.79848

Velicky P, Miguel Villalba E, Michalska JM, et al. Saturated reconstruction of living brain tissue. bioRxiv. doi:10.1101/2022.03.16.484431

Michalska JM, Lyudchik J, Velicky P, et al. Uncovering brain tissue architecture across scales with super-resolution light microscopy. bioRxiv. doi:10.1101/2022.08.17.504272

Zhang X, Schlögl A, Vandael DH, Jonas PM. MOD: A novel machine-learning optimal-filtering method for accurate and efficient detection of subthreshold synaptic events in vivo. Journal of Neuroscience Methods. 2021;357(6). doi:10.1016/j.jneumeth.2021.109125

Vandael DH, Okamoto Y, Jonas PM. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. Nature Communications. 2021;12(1). doi:10.1038/s41467-021-23153-5

Vandael DH, Okamoto Y, Borges Merjane C, Vargas Barroso VM, Suter B, Jonas PM. Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. Nature Protocols. 2021;16(6):2947–2967. doi:10.1038/s41596-021-00526-0

Guzmán J, Schlögl A, Espinoza Martinez C, Zhang X, Suter B, Jonas PM. How connectivity rules and synaptic properties shape the efficacy of pattern separation in the entorhinal cortex–dentate gyrus–C network. Nature Computational Science. 2021;1(12):830-842. doi:10.1038/s43588-021-00157-1

Guzmán J, Schlögl A, Espinoza Martinez C, Zhang X, Suter B, Jonas PM. How connectivity rules and synaptic properties shape the efficacy of pattern separation in the entorhinal cortex–dentate gyrus–C network. 2021. doi:10.15479/AT:ISTA:10110

Bhandari P, Vandael DH, Fernández-Fernández D, et al. GABAB receptor auxiliary subunits modulate Ca.3-mediated release from medial habenula terminals. eLife. 2021;10. doi:10.7554/ELIFE.68274

Vandael DH, Borges Merjane C, Zhang X, Jonas PM. Short-term plasticity at hippocampal mossy fiber synapses is induced by natural activity patterns and associated with vesicle pool engram formation. Neuron. 2020;107(3):509-521. doi:10.1016/j.neuron.2020.05.013

Zhang X, Schlögl A, Jonas PM. Selective routing of spatial information flow from input to output in hippocampal granule cells. Neuron. 2020;107(6):1212-1225. doi:10.1016/j.neuron.2020.07.006

Borges Merjane C, Kim O, Jonas PM. Functional electron microscopy (“Flash and Freeze”) of identified cortical synapses in acute brain slices. Neuron. 2020;105:992-1006. doi:10.1016/j.neuron.2019.12.022

Kim O, Borges Merjane C, Jonas PM. Functional analysis of the docked vesicle pool in hippocampal mossy fiber terminals by electron microscopy. In: Intrinsic Activity. Vol 7. Austrian Pharmacological Society; 2019. doi:10.25006/ia.7.s1-a3.27

Hu H, Roth F, Vandael DH, Jonas PM. Complementary tuning of Na+ and K+ channel gating underlies fast and energy-efficient action potentials in GABAergic interneuron axons. Neuron. 2018;98(1):156-165. doi:10.1016/j.neuron.2018.02.024

Espinoza Martinez C, Guzmán J, Zhang X, Jonas PM. Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus. Nature Communications. 2018;9(1). doi:10.1038/s41467-018-06899-3

Gan J, Weng S-M, Pernia-Andrade A, Csicsvari JL, Jonas PM. Phase-locked inhibition, but not excitation, underlies hippocampal ripple oscillations in awake mice in vivo. Neuron. 2017;93(2):308-314. doi:10.1016/j.neuron.2016.12.018

Chen C, Arai10.1016/j.celrep.2016.12.067__itaru, Satterield R, Young S, Jonas PM. Synaptotagmin 2 is the fast C+ sensor at a central inhibitory synapse. Cell Reports. 2017;18(3):723-736. doi:10.1016/j.celrep.2016.12.067

Chen C, Jonas PM. Synaptotagmins: That’s why so many. Neuron. 2017;94(4):694-696. doi:10.1016/j.neuron.2017.05.011

Strüber M, Sauer J, Jonas PM, Bartos M. Distance-dependent inhibition facilitates focality of gamma oscillations in the dentate gyrus. Nature Communications. 2017;8(1). doi:10.1038/s41467-017-00936-3

Chen C, Satterfield R, Young S, Jonas PM. Triple function of Synaptotagmin 7 ensures efficiency of high-frequency transmission at central GABAergic synapses. Cell Reports. 2017;21(8):2082-2089. doi:10.1016/j.celrep.2017.10.122

Vyleta N, Borges Merjane C, Jonas PM. Plasticity-dependent, full detonation at hippocampal mossy fiber–C pyramidal neuron synapses. eLife. 2016;5. doi:10.7554/eLife.17977

Guzmán J, Schlögl A, Frotscher M, Jonas PM. Synaptic mechanisms of pattern completion in the hippocampal C network. Science. 2016;353(6304):1117-1123. doi:10.1126/science.aaf1836

Mishra RK, Kim S, Guzmán J, Jonas PM. Symmetric spike timing-dependent plasticity at C–C synapses optimizes storage and recall in autoassociative networks. Nature Communications. 2016;7. doi:10.1038/ncomms11552

Kowalski J, Gan J, Jonas PM, Pernia-Andrade A. Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats. Hippocampus. 2016;26(5):668-682. doi:10.1002/hipo.22550

Hammer M, Krueger Burg D, Tuffy L, et al. Perturbed hippocampal synaptic inhibition and ;3-oscillations in a neuroligin-4 knockout mouse model of autism. Cell Reports. 2015;13(3):516-523. doi:10.1016/j.celrep.2015.09.011

Strüber M, Jonas PM, Bartos M. Strength and duration of perisomatic GABAergic inhibition depend on distance between synaptically connected cells. PNAS. 2015;112(4):1220-1225. doi:10.1073/pnas.1412996112

Vandael DH, Espinoza Martinez C, Jonas PM. Excitement about inhibitory presynaptic terminals. Neuron. 2015;85(6):1149-1151. doi:10.1016/j.neuron.2015.03.006

Arai10.7554/eLife.04057__itaru, Jonas PM. Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. eLife. 2014;3. doi:10.7554/eLife.04057

Jonas PM, Lisman J. Structure, function and plasticity of hippocampal dentate gyrus microcircuits. Frontiers in Neural Circuits. 2014;8. doi:10.3389/fncir.2014.00107

Hu H, Gan J, Jonas PM. Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to microcircuit function. Science. 2014;345(6196). doi:10.1126/science.1255263

Studer D, Zhao S, Chai X, et al. Capture of activity-induced ultrastructural changes at synapses by high-pressure freezing of brain tissue. Nature Protocols. 2014;9(6):1480-1495. doi:10.1038/nprot.2014.099

Hu H, Jonas PM. A supercritical density of Na^+ channels ensures fast signaling in GABAergic interneuron axons. Nature Neuroscience. 2014;17(5):686-693. doi:10.1038/nn.3678

Vyleta N, Jonas PM. Loose coupling between Ca^2+ channels and release sensors at a plastic hippocampal synapse. Science. 2014;343(6171):665-670. doi:10.1126/science.1244811

Pernia-Andrade A, Jonas PM. Theta-gamma-modulated synaptic currents in hippocampal granule cells in vivo define a mechanism for network oscillations. Neuron. 2014;81(1):140-152. doi:10.1016/j.neuron.2013.09.046

Hosp J, Strüber M, Yanagawa Y, et al. Morpho-physiological criteria divide dentate gyrus interneurons into classes. Hippocampus. 2014;23(2):189-203. doi:10.1002/hipo.22214

Schlögl A, Jonas PM, Schmidt-Hieber C, Guzman SJ. Stimfit: A fast visualization and analysis environment for cellular neurophysiology. Biomedical Engineering / Biomedizinische Technik. 2013;58(SI-1-Track-G). doi:10.1515/bmt-2013-4181

Pernia-Andrade A, Goswami S, Stickler Y, Fröbe U, Schlögl A, Jonas PM. A deconvolution based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo. Biophysical Journal. 2012;103(7):1429-1439. doi:10.1016/j.bpj.2012.08.039

Goswami S, Bucurenciu I, Jonas PM. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. Journal of Neuroscience. 2012;32(41):14294-14304. doi:10.1523/JNEUROSCI.6104-11.2012

Eggermann E, Bucurenciu I, Goswami S, Jonas PM. Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses. Nature Reviews Neuroscience. 2012;13(1):7-21. doi:10.1038/nrn3125

Kim S, Guzmán J, Hu H, Jonas PM. Active dendrites support efficient initiation of dendritic spikes in hippocampal C pyramidal neurons. Nature Neuroscience. 2012;15(4):600-606. doi:10.1038/nn.3060

Eggermann E, Jonas PM. How the “slow”10.1038/nn.3002__Ca(2+) buffer parvalbumin affects transmitter release in nanodomain coupling regimes at GABAergic synapses. Nature Neuroscience. 2011;15:20-22. doi:10.1038/nn.3002

Pernia-Andrade A, Jonas PM. The multiple faces of RIM. Neuron. 2011;69(2):185-187. doi:10.1016/j.neuron.2011.01.010

Fakler B, Jonas PM. Grundlagen zellulärer Erregbarkeit. In: Schmidt R, Heckmann M, Lang F, eds. Physiologie Des Menschen. Springer; 2010.

Norenberg A, Hu H, Vida I, Bartos M, Jonas PM. Distinct nonuniform cable properties optimize rapid and efficient activation of fast-spiking GABAergic interneurons. PNAS. 2010;107(2):894-899. doi:10.1073/pnas.0910716107

Guzmán J, Jonas PM. Beyond TARPs: The growing list of auxiliary AMPAR subunits. Neuron. 2010;66(1):8-10. doi:10.1016/j.neuron.2010.04.003

Hu H, Martina M, Jonas PM. Dendritic mechanisms underlying rapid synaptic activation of fast-spiking hippocampal interneurons. Science. 2010;327(5961):52-58. doi:10.1126/science.1177876

Jonas PM, Hefft S. GABA release at terminals of CCK-interneurons: synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali &;amp; Todorova). The European Journal of Neuroscience. 2010;31(7):1194-1195. doi:10.1111/j.1460-9568.2010.07189.x

Bucurenciu I, Bischofberger J, Jonas PM. A small number of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse. Nature Neuroscience. 2010;13(1):19-21. doi:10.1038/nn.2461 

Schwenk J, Harmel N, Zolles G, et al. Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Science. 2009;323(5919):1313-1319. doi:10.1126/science.1167852

Doischer D, Hosp J, Yanagawa Y, et al. Postnatal differentiation of basket cells from slow to fast signaling devices. Journal of Neuroscience. 2008;28(48):12956-12968. doi:10.1523/JNEUROSCI.2890-08.2008

Kerr A, Reisinger E, Jonas PM. Differential dependence of phasic transmitter release on synaptotagmin 1 at GABAergic and glutamatergic hippocampal synapses. PNAS. 2008;105(40):15581-15586. doi:10.1073/pnas.0800621105

Aponte Y, Bischofberger J, Jonas PM. Efficient Ca(2+) buffering in fast-spiking basket cells of rat hippocampus. Journal of Physiology. 2008;586(8):2061-2075. doi:10.1113/jphysiol.2007.147298

Schmidt Hieber C, Jonas PM, Bischofberger J. Action potential initiation and propagation in hippocampal mossy fibre axons. Journal of Physiology. 2008;586(7):1849-1857. doi:10.1113/jphysiol.2007.150151 

Bucurenciu I, Kulik Á, Schwaller B, Frotscher M, Jonas PM. Nanodomain coupling between Ca(2+) channels and C+ sensors promotes fast and efficient transmitter release at a cortical GABAergic synapse. Neuron. 2008;57(4):536-545. doi:10.1016/j.neuron.2007.12.026

Kerr A, Jonas PM. The two sides of hippocampal mossy fiber plasticity (Review). Neuron. 2008;57(1):5-7. doi:10.1016/j.neuron.2007.12.015

Bartos M, Vida I, Jonas PM. Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks (Review). Nature Reviews Neuroscience. 2007;8(1):45-56. doi:10.1038/nrn2044 

Jonas PM, Buzsáki G. Neural inhibition. Scholarpedia. 2007;2. doi:10.4249/scholarpedia.3286

Schmidt Hieber C, Jonas PM, Bischofberger J. Subthreshold dendritic signal processing and coincidence detection in dentate gyrus granule cells. Journal of Neuroscience. 2007;27(31):8430-8441. doi:10.1523/JNEUROSCI.1787-07.2007

Rollenhagen A, Satzler K, Rodriguez EP, Jonas PM, Frotscher M, Lubke J. Structural determinants of transmission at large hippocampal mossy fiber synapses. Journal of Neuroscience. 2007;27(39):10434-10444. doi:10.1523/JNEUROSCI.1946-07.2007

Li L, Bischofberger J, Jonas PM. Differential gating and recruitment of P/Q-, N-, and R-type Ca(2+) channels in hippocampal mossy fiber boutons. Journal of Neuroscience. 2007;27(49):13420-13429. doi:10.1523/JNEUROSCI.1709-07.2007

Aponte Y, Lien C, Reisinger E, Jonas PM. Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus. Journal of Physiology. 2006;574(Pt 1):229-243. doi:10.1113/jphysiol.2005.104042

Frotscher M, Jonas PM, Sloviter R. Synapses formed by normal and abnormal hippocampal mossy fibers (Review). Cell and Tissue Research. 2006;326(2):361-367. doi:10.1007/s00441-006-0269-2

Bischofberger J, Engel D, Frotscher M, Jonas PM. Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. Pflugers Archivf: European Journal of Physiology. 2006;453(3):361-372. doi:10.1007/s00424-006-0093-2

Vida I, Bartos M, Jonas PM. Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron. 2006;49(1):107-117. doi:10.1016/j.neuron.2005.11.036

Frotscher M, Gundelfinger E, Jonas PM, Neher E, Seeburg P. The most important recent advances in synapse research from my point of view--and what remains to be done. Cell and Tissue Research. 2006;326(2):203-204. doi:10.1007/s00441-006-0325-y

Bischofberger J, Engel D, Frotscher M, Jonas PM. Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network. (Review). Pflugers Archivf: European Journal of Physiology. 2006;453(3):361-372. doi:10.1007/s00424-006-0093-2

Bischofberger J, Engel D, Li L, Geiger J, Jonas PM. Patch-clamp recording from mossy fiber terminals in hippocampal slices. Nature Protocols. 2006;1(4):2075-2081. doi:10.1038/nprot.2006.312 

Hefft S, Jonas PM. Asynchronous GABA release generates long-lasting inhibition at a hippocampal interneuron-principal neuron synapse (Review). Nature Neuroscience. 2005;8(10):1319-1328. doi:10.1038/nn1542

Engel D, Jonas PM. Presynaptic action potential amplification by voltage-gated Na+ channels in hippocampal mossy fiber boutons. Neuron. 2005;45(3):405-417. doi:10.1016/j.neuron.2004.12.048 

Oliver D, Lien C, Soom M, Baukrowitz T, Jonas PM, Fakler B. Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids. Science. 2004;304(5668):265-270. doi:10.1126/science.1094113

Kampa B, Clements J, Jonas PM, Stuart G. Kinetics of Mg(2+) unblock of NMDA receptors: implications for spike-timing dependent synaptic plasticity. Journal of Physiology. 2004;556(Pt 2):337-345. doi:10.1113/jphysiol.2003.058842 

Schmidt Hieber C, Jonas PM, Bischofberger J. Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. Nature. 2004;429(6988):184-187. doi:10.1038/nature02553

Jonas PM, Bischofberger J, Fricker D, Miles R. Interneuron Diversity series: Fast in, fast out--temporal and spatial signal processing in hippocampal interneurons. Trends in Neurosciences. 2004;27(1):30-40. doi:doi:10.1016/j.tins.2003.10.010

Jonas PM, Unsicker K. Molekulare und zelluläre Grundlagen des Nervensystems. In: Schmidt R, ed. Lehrbuch Vorklinik. Vol B. Deutscher Ärzte Verlag; 2003:3-26.

Lien C, Jonas PM. K potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons. Journal of Neuroscience. 2003;23(6):2058-2068.

Hallermann S, Pawlu C, Jonas PM, Heckmann M. A large pool of releasable vesicles in a cortical glutamatergic synapse. PNAS. 2003;100(15):8975-8980. doi:10.1073/pnas.1432836100

Bischofberger J, Geiger J, Jonas PM. Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of Neuroscience. 2002;22(24):10593-10602. doi:10.1523/JNEUROSCI.22-24-10593.2002

Bartos M, Vida I, Frotscher M, et al. Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. PNAS. 2002;99(20):13222-13227. doi:10.1073/pnas.192233099

Bischofberger J, Jonas PM. TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in Neurosciences. 2002;25(12):600-603. doi:10.1016/S0166-2236(02)02259-2

Hefft S, Kraushaar U, Geiger J, Jonas PM. Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus. Journal of Physiology. 2002;539(Pt 1):201-208. doi:10.1113/jphysiol.2001.013455

Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus. Journal of Physiology. 2002;538(Pt 2):405-419. doi:10.1113/jphysiol.2001.013066

Geiger J, Bischofberger J, Vida I, et al. Patch-clamp recording in brain slices with improved slicer technology. Pflugers Archivf: European Journal of Physiology. 2002;443(3):491-501. doi:10.1007/s00424-001-0735-3

Bartos M, Vida I, Frotscher M, Geiger J, Jonas PM. Rapid signaling at inhibitory synapses in a dentate gyrus interneuron network. Journal of Neuroscience. 2001;21(8):2687-2698. doi:10.1523/JNEUROSCI.21-08-02687.2001

Alle H, Jonas PM, Geiger J. PTP and LTP at a hippocampal mossy fiber-interneuron synapse. PNAS. 2001;98(25):14708-14713. doi:10.1073/pnas.251610898 

Jerecic J, Schulze C, Jonas PM, Sprengel R, Seeburg P, Bischofberger J. Impaired NMDA receptor function in mouse olfactory bulb neurons by tetracycline-sensitive N (N598R) expression. Molecular Brain Research. 2001;94(1-2):96-104. doi:10.1016/S0169-328X(01)00221-2

Jones M., Jonas PM, Sahara Y, Westbrook G. Microscopic kinetics and energetics distinguish GABAA receptor agonists from antagonists. Biophysical Journal. 2001;81(5):2660-2670. doi:10.1016/S0006-3495(01)75909-7 

Jonas PM. The time course of signaling at central glutamatergic synapses. Physiology. 2000;15(2):83-89. doi:10.1152/physiologyonline.2000.15.2.83

Geiger J, Jonas PM. Dynamic control of presynaptic Ca(2+) inflow by fast-inactivating K+ channels in hippocampal mossy fiber boutons. Neuron. 2000;28(3):927-939. doi:10.1016/S0896-6273(00)00164-1

Martina M, Vida I, Jonas PM. Distal initiation and active propagation of action potentials in interneuron dendrites. Science. 2000;287(5451):295-300. doi:10.1126/science.287.5451.295

Kraushaar U, Jonas PM. Efficacy and stability of quantal GABA release at a hippocampal interneuron-principal neuron synapse. Journal of Neuroscience. 2000;20(15):5594-5607. doi:10.1523/JNEUROSCI.20-15-05594.2000

Normann C, Peckys D, Schulze C, Walden J, Jonas PM, Bischofberger J. Associative long-term depression in the hippocampus is dependent on postsynaptic N-type Ca(2+) channels. Journal of Neuroscience. 2000;20(22):8290-8297. doi:10.1523/JNEUROSCI.20-22-08290.2000

Jonas PM, Monyer H, eds. Ionotropic Glutamate Receptors in the CNS. Vol 141. 1st ed. Berlinf; Heidelberg: Springer; 1999. doi:10.1007/978-3-662-08022-1

Monyer H, Jonas PM, Rossier J. Molecular determinants controlling functional properties of AMPARs and NMDARs in the mammalian CNS. In: Jonas PM, Monyer H, eds. Ionotropic Glutamate Receptors in the CNS. Vol 141. Springer; 1999:309-339. doi:10.1007/978-3-662-08022-1_9