Lifelong persistence of nuclear RNAs in the mouse brain
S. Zocher, A. Mccloskey, A. Karasinsky, R. Schulte, U. Friedrich, M. Lesche, N. Rund, F.H. Gage, M. Hetzer, T. Toda, Science 384 (2024) 53–59.

Lamin  overexpression alters chromatin organization and gene expression
J.M. Kaneshiro, J.S. Capitanio, M. Hetzer, Nucleus 14 (2023).

Caspase-mediated nuclear pore complex trimming in cell differentiation and endoplasmic reticulum stress
U.H. Cho, M. Hetzer, ELife 12 (2023).

Nuclear pore complex maintenance and implications for age-related diseases
J. Liu, M. Hetzer, Trends in Cell Biology 32 (2022) 6-227.

The San Diego Nathan Shock Center: Tackling the heterogeneity of aging
G.S. Shadel, P.D. Adams, W.T. Berggren, J.K. Diedrich, K.E. Diffenderfer, F.H. Gage, N. Hah, M. Hansen, M. Hetzer, A.J.A. Molina, U. Manor, K. Marek, D.D. O’Keefe, A.F.M. Pinto, A. Sacco, T.O. Sharpee, M.N. Shokriev, S. Zambetti, GeroScience 43 (2021) 2139–2148.

Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain
S. Krishna, R. Arrojo e Drigo, J.S. Capitanio, R. Ramachandra, M. Ellisman, M. Hetzer, Developmental Cell 56 (2021) 52–2965.e9.

Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease
S. Bersini, R. Arrojo e Drigo, L. Huang, M.N. Shokhirev, M. Hetzer, Advanced Biosystems 4 (2020).

Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome
S. Bersini, R. Schulte, L. Huang, H. Tsai, M. Hetzer, ELife 9 (2020).

Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging
U.H. Cho, M. Hetzer, Neuron 106 (2020) 899–911.

Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation
H. Kang, M.N. Shokhirev, Z. Xu, S. Chandran, J.R. Dixon, M. Hetzer, Genes &; Development 34 (2020) 913–930.

Nu regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling
S. Bersini, N.K. Lytle, R. Schulte, L. Huang, G.M. Wahl, M. Hetzer, Life Science Alliance 3 (2020).

Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells
B.H. Toyama, R. Arrojo e Drigo, V. Lev-Ram, R. Ramachandra, T.J. Deerinck, C. Lechene, M.H. Ellisman, M. Hetzer, Journal of Cell Biology 218 (2019) 433–444.

Age mosaicism across multiple scales in adult tissues
R. Arrojo e Drigo, V. Lev-Ram, S. Tyagi, R. Ramachandra, T. Deerinck, E. Bushong, S. Phan, V. Orphan, C. Lechene, M.H. Ellisman, M. Hetzer, Cell Metabolism 30 (2019) 343–351.e3.

Coaching from the sidelines: The nuclear periphery in genome regulation
A. Buchwalter, J.M. Kaneshiro, M. Hetzer, Nature Reviews Genetics 20 (2019) 39–50.

Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, ELife 8 (2019).

Data from: Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, (2019).

Tpr regulates the total number of nuclear pore complexes per cell nucleus
A. McCloskey, A. Ibarra, M. Hetzer, Genes &; Development 32 (2018) 1321–1331.

Predicting age from the transcriptome of human dermal fibroblasts
J.G. Fleischer, R. Schulte, H.H. Tsai, S. Tyagi, A. Ibarra, M.N. Shokhirev, L. Huang, M. Hetzer, S. Navlakha, Genome Biology 19 (2018).

Nu recruits the Wd–SeA/COMPASS complex to promoters to regulate K4 trimethylation in hematopoietic progenitor cells
T.M. Franks, A. McCloskey, M.N. Shokhirev, C. Benner, A. Rathore, M. Hetzer, Genes &; Development 31 (2017) 2222–2234.

Nu3 interacts with So to enable bimodal gene regulation and maintenance of neural progenitor cells
T. Toda, J.Y. Hsu, S.B. Linker, L. Hu, S.T. Schafer, J. Mertens, F.V. Jacinto, M. Hetzer, F.H. Gage, Cell Stem Cell 21 (2017) 618–634.e7.

Nucleolar expansion and elevated protein translation in premature aging
A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).

0-catenin prevents multinucleation through control of MKL-dependent RhoA activity during cytokinesis
R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong, K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M. Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).

Evolution of a transcriptional regulator from a transmembrane nucleoporin
T.M. Franks, C. Benner, I. Narvaiza, M.C.N. Marchetto, J.M. Young, H.S. Malik, F.H. Gage, M. Hetzer, Genes &; Development 30 (2016) 1155–1171.

Nuclear envelope rupture is induced by actin-based nucleus confinement
E.M. Hatch, M. Hetzer, Journal of Cell Biology 215 (2016) 27–36.

Nucleoporin-mediated regulation of cell identity genes
A. Ibarra, C. Benner, S. Tyagi, J. Cool, M. Hetzer, Genes &; Development 30 (2016) 2253–2258.

Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects
J. Mertens, A.C.M. Paquola, M. Ku, E. Hatch, L. Böhnke, S. Ladjevardi, S. McGrath, B. Campbell, H. Lee, J.R. Herdy, J.T. Gonçalves, T. Toda, Y. Kim, J. Winkler, J. Yao, M. Hetzer, F.H. Gage, Cell Stem Cell 17 (2015) 705–718.

The nucleoporin Nu3 regulates embryonic stem cell pluripotency through gene silencing
F.V. Jacinto, C. Benner, M. Hetzer, Genes &; Development 29 (2015) 1224–1238.

Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats
A. Ori, B.H. Toyama, M.S. Harris, T. Bock, M. Iskar, P. Bork, N.T. Ingolia, M. Hetzer, M. Beck, Cell Systems 1 (2015) 4-237.

The nucleoporin /Nu0 controls muscle differentiation by regulating nuclear envelope/ER homeostasis
J.S. Gomez-Cavazos, M. Hetzer, Journal of Cell Biology 208 (2015) 671–681.

Nuclear pore proteins and the control of genome functions
A. Ibarra, M. Hetzer, Genes &; Development 29 (2015) 337–349.

Linking micronuclei to chromosome fragmentation
E.M. Hatch, M. Hetzer, Cell 161 (2015) 1502–1504.

Chromothripsis
E.M. Hatch, M. Hetzer, Current Biology 25 (2015) -9.

Nuclear pores set the speed limit for mitosis
A. Buchwalter, M. Hetzer, Cell 156 (2014) 868–869.

Nu is required for cell differentiation and exhibits transcription-dependent dynamics
A.L. Buchwalter, Y. Liang, M. Hetzer, Molecular Biology of the Cell 25 (2014) 2472–2484.

Breaching the nuclear envelope in development and disease
E. Hatch, M. Hetzer, Journal of Cell Biology 205 (2014) 133–141.

Dynamic association of NU with the human genome
Y. Liang, T.M. Franks, M.C. Marchetto, F.H. Gage, M. Hetzer, PLoS Genetics 9 (2013).

Identification of long-lived proteins reveals exceptional stability of essential cellular structures
B.H. Toyama, J.N. Savas, S.K. Park, M.S. Harris, N.T. Ingolia, J.R. Yates, M. Hetzer, Cell 154 (2013) 971–982.

Catastrophic nuclear envelope collapse in cancer cell micronuclei
E.M. Hatch, A.H. Fischer, T.J. Deerinck, M. Hetzer, Cell 154 (2013) 47–60.

Anomalous diffusion of single particles in cytoplasm
B.M. Regner, D. Vudini, C. Domnisoru, T.M. Bartol, M. Hetzer, D.M. Tartakovsky, T.J. Sejnowski, Biophysical Journal 104 (2013) 1652–1660.

The role of Nu in transcription regulation in healthy and diseased cells
T.M. Franks, M. Hetzer, Trends in Cell Biology 23 (2013) 112–117.

Protein homeostasis: Live long, won't prosper
B.H. Toyama, M. Hetzer, Nature Reviews Molecular Cell Biology 14 (2013) 55–61.

Outfits for different occasions: tissue-specific roles of Nuclear Envelope proteins
J.S. Gomez-Cavazos, M. Hetzer, Current Opinion in Cell Biology 24 (2012) 775–783.

Transient nuclear envelope rupturing during interphase in human cancer cells
J.D. Vargas, E.M. Hatch, D.J. Anderson, M. Hetzer, Nucleus 3 (2012) 88–100.

A change in nuclear pore complex composition regulates cell differentiation
M.A. D’Angelo, J.S. Gomez-Cavazos, A. Mei, D.H. Lackner, M. Hetzer, Developmental Cell 22 (2012) 446–458.

Extremely long-lived nuclear pore proteins in the rat brain
J.N. Savas, B.H. Toyama, T. Xu, J.R. Yates, M. Hetzer, Science 335 (2012) 942–942.

RNP export by nuclear envelope budding
E.M. Hatch, M. Hetzer, Cell 149 (2012) 733–735.

POM121 and Sun1 play a role in early steps of interphase NPC assembly
J.A. Talamas, M. Hetzer, Journal of Cell Biology 194 (2011) 27–37.

Functional interactions between nucleoporins and chromatin
Y. Liang, M. Hetzer, Current Opinion in Cell Biology 23 (2011) 65–70.

Editorial overview
M. Hetzer, G. Cavalli, Current Opinion in Cell Biology 23 (2011) 255–257.

Nuclear pore complexes: Guardians of the nuclear genome
M. Capelson, C. Doucet, M. Hetzer, Cold Spring Harbor Symposia on Quantitative Biology 75 (2011) 585–597.

The nuclear envelope
M. Hetzer, Cold Spring Harbor Perspectives in Biology 2 (2010) 0539–0539.

Nuclear pore biogenesis into an intact nuclear envelope
C.M. Doucet, M. Hetzer, Chromosoma 119 (2010) 469–477.

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes
M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, M. Hetzer, Cell 140 (2010) 372–383.

Cell cycle-dependent differences in nuclear pore complex assembly in metazoa
C.M. Doucet, J.A. Talamas, M. Hetzer, Cell 141 (2010) 1030–1041.

The role of the nuclear pore complex in aging of post-mitotic cells
M. Hetzer, Aging 2 (2010) 74–75.

Border control at the nucleus: Biogenesis and organization of the nuclear membrane and pore complexes
M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.

Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo
D.J. Anderson, J.D. Vargas, J.P. Hsiao, M. Hetzer, Journal of Cell Biology 186 (2009) 183–191.

ER membrane–bending proteins are necessary for de novo nuclear pore formation
T.R. Dawson, M.D. Lazarus, M. Hetzer, S.R. Wente, Journal of Cell Biology 184 (2009) 659–675.

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells
M.A. D’Angelo, M. Raices, S.H. Panowski, M. Hetzer, Cell 136 (2009) 284–295.

The role of nuclear pores in gene regulation, development and disease
M. Capelson, M. Hetzer, EMBO Reports 10 (2009) 697–705.

Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation
D.J. Anderson, M. Hetzer, Journal of Cell Biology 182 (2008) 911–924.

Structure, dynamics and function of nuclear pore complexes
M.A. D’Angelo, M. Hetzer, Trends in Cell Biology 18 (2008) 456–466.

Reorganization of the nuclear envelope during open mitosis
U. Kutay, M. Hetzer, Current Opinion in Cell Biology 20 (2008) 669–677.

The life cycle of the metazoan nuclear envelope
D.J. Anderson, M. Hetzer, Current Opinion in Cell Biology 20 (2008) 386–392.

Shaping the endoplasmic reticulum into the nuclear envelope
D.J. Anderson, M. Hetzer, Journal of Cell Science 121 (2008) 137–142.

Single bead affinity detection (SINBAD) for the analysis of protein-protein interactions
R. Schulte, J. Talamas, C. Doucet, M. Hetzer, PLoS ONE 3 (2008).

MEL28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly
C. Franz, R. Walczak, S. Yavuz, R. Santarella, M. Gentzel, P. Askjaer, V. Galy, M. Hetzer, I.W. Mattaj, W. Antonin, EMBO Reports 8 (2007) 165–172.

Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum
D.J. Anderson, M. Hetzer, Nature Cell Biology 9 (2007) 1160–1166.

In Vitro Techniques
J.R. Harris, G. Almouzni, D. Kirschner, D. Dimitrova, J.A. Nickerson, J. Underwood, S. Wagner, B. Korbei, R. Foisner, T.C. Walther, M. Hetzer, R. Peters, I. Walev, A.I.P.M. de Kroon, R.W.H.M. Staffhorst, B. de Kruijff, K.N.J. Burger, L.E.S. Netto, E. Bertrand, J.B. Alimonti, A.H. Greenberg, J. Xiao, A. Pradhan, Y. Liu, J. Paiement, R. Young, F.M. Goñi, A.-V. Villar, F.-X. Contreras, A. Alonso, B.J. Peter, I.G. Mills, M.K. Higgins, W.J. Brown, K. Chambers, A. Doody, C.Y. Cheng, D.D. Mruk, C. Yang, H. Kirchhoff, W. Haase, S. Boggasch, H. Paulsen, J. Benesova, S.-T. Liffers, M. Rögner, Y. Gao, E. Sztul, M. Thiemann, H.D. Fahimi, R. Gniadecki, B. Gajkowska, S.L. Bane, J.F. Hess, J.C. Voss, P.G. Fitzgerald, S. Hisanaga, T. Sasaki, K. Uéda, T. Town, J. Tan, N.G.N. Milton, R. Chi, T.C.S. Keller, M. Kriajevska, I. Bronstein, E. Lukanidin, D.F. Holmes, K.E. Kadler, in:, R. Harris, J. Graham, D. Rickwood (Eds.), Cell Biology Protocols, Wiley, Chichester, UK, 2006, pp. 201–378.

The role of the nuclear envelope in cellular organization
M.A. D’Angelo, M. Hetzer, Cellular and Molecular Life Sciences 63 (2006) 316–332.

Nuclear pores form de novo from both sides of the nuclear envelope
M.A. D’Angelo, D.J. Anderson, E. Richard, M. Hetzer, Science 312 (2006) 440–443.

Pushing the envelope: Structure, function, and dynamics of the nuclear periphery
M. Hetzer, T.C. Walther, I.W. Mattaj, Annual Review of Cell and Developmental Biology 21 (2005) 347–380.

The conserved Nu7-160 complex is critical for nuclear pore complex assembly
T.C. Walther, A. Alves, H. Pickersgill, I. Loodice, M. Hetzer, V. Galy, B.B. Hülsmann, T. Köcher, M. Wilm, T. Allen, I.W. Mattaj, V. Doye, Cell 113 (2003) 195–206.

RanGTP mediates nuclear pore complex assembly
T.C. Walther, P. Askjaer, M. Gentzel, A. Habermann, G. Griffiths, M. Wilm, I.W. Mattaj, M. Hetzer, Nature 424 (2003) 689–694.

Ran binds to chromatin by two distinct mechanisms
D. Bilbao-Cortés, M. Hetzer, G. Längst, P.B. Becker, I.W. Mattaj, Current Biology 12 (2002) 1151–1156.

The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly
M. Hetzer, O.J. Gruss, I.W. Mattaj, Nature Cell Biology 4 (2002) 7–4.

Distinct AAA-ATPase  complexes function in discrete steps of nuclear assembly
M. Hetzer, H.H. Meyer, T.C. Walther, D. Bilbao-Cortes, G. Warren, I.W. Mattaj, Nature Cell Biology 3 (2001) 1086–1091.

An Atp-dependent, Ran-independent mechanism for nuclear import of the a and b spliceosome proteins
M. Hetzer, I.W. Mattaj, Journal of Cell Biology 148 (2000) 293–304.

GTP hydrolysis by Ran is required for nuclear envelope assembly
M. Hetzer, D. Bilbao-Cortés, T.C. Walther, O.J. Gruss, I.W. Mattaj, Molecular Cell 5 (2000) 1013–1024.