Hibshman GN, Bravo JPK, Hooper MM, et al. Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Ca. Nature Communications. 2024;15. doi:10.1038/s41467-024-47830-3
LibreCat: https://research-explorer.ista.ac.at/record/15372
DOI: 10.1038/s41467-024-47830-3
PMID: 38688943

Schwartz EA, Bravo JPK, Ahsan M, et al. RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nature Communications. 2024;15. doi:10.1038/s41467-024-47506-y
LibreCat: https://research-explorer.ista.ac.at/record/17114
DOI: 10.1038/s41467-024-47506-y
PMID: 38637512

Hibshman GN, Bravo JPK, Hooper MM, et al. Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Ca. Nature Communications. 2024;15. doi:10.1038/s41467-024-47830-3
LibreCat: https://research-explorer.ista.ac.at/record/17113
DOI: 10.1038/s41467-024-47830-3
PMID: 38688943

Kamatar A, Bravo JPK, Yuan F, et al. Lipid droplets as substrates for protein phase separation. Biophysical Journal. doi:10.1016/j.bpj.2024.03.015
LibreCat: https://research-explorer.ista.ac.at/record/17111
DOI: 10.1016/j.bpj.2024.03.015
PMID: 38462838

Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson RN, Taylor DW. RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Ca. Nature. 2023;613(7944):582-587. doi:10.1038/s41586-022-05560-w
LibreCat: https://research-explorer.ista.ac.at/record/15130
DOI: 10.1038/s41586-022-05560-w
PMID: 36599980

O’Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Molecular Cell. 2023;83(5):746-758.e5. doi:10.1016/j.molcel.2023.01.024
LibreCat: https://research-explorer.ista.ac.at/record/15129
DOI: 10.1016/j.molcel.2023.01.024
PMID: 36805026

Steens JA, Bravo JPK, Salazar CRP, et al. Type III-B CRISPR-Cas signaling-based cascade of proteolytic cleavages. bioRxiv. 2023. doi:10.1101/2023.06.23.546230
LibreCat: https://research-explorer.ista.ac.at/record/17112
DOI: 10.1101/2023.06.23.546230

Bravo JPK. SuperFi-Ca exceeds fidelity, matches speed of original Ca. Genetic Engineering &; Biotechnology News. 2022;42(4):12. doi:10.1089/gen.42.04.03
LibreCat: https://research-explorer.ista.ac.at/record/15144
DOI: 10.1089/gen.42.04.03

Schwartz EA, McBride TM, Bravo JPK, et al. Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. Nature Communications. 2022;13. doi:10.1038/s41467-022-30402-8
LibreCat: https://research-explorer.ista.ac.at/record/15134
DOI: 10.1038/s41467-022-30402-8
PMID: 35595728

Yelland JN, Bravo JPK, Black JJ, Taylor DW, Johnson AW. A single 2-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Nature Structural &; Molecular Biology. 2022;30:91-98. doi:10.1038/s41594-022-00891-8
LibreCat: https://research-explorer.ista.ac.at/record/15131
DOI: 10.1038/s41594-022-00891-8
PMID: 36536102

Bravo JPK, Aparicio-Maldonado C, Nobrega FL, Brouns SJJ, Taylor DW. Structural basis for broad anti-phage immunity by DISARM. Nature Communications. 2022;13. doi:10.1038/s41467-022-30673-1
LibreCat: https://research-explorer.ista.ac.at/record/15133
DOI: 10.1038/s41467-022-30673-1
PMID: 35624106

Bravo JPK, Hibshman GN, Taylor DW. Constructing next-generation CRISPR–Cas tools from structural blueprints. Current Opinion in Biotechnology. 2022;78. doi:10.1016/j.copbio.2022.102839
LibreCat: https://research-explorer.ista.ac.at/record/15132
DOI: 10.1016/j.copbio.2022.102839
PMID: 36371895

Bravo JPK, Liu M-S, Hibshman GN, et al. Structural basis for mismatch surveillance by CRISPR–Ca. Nature. 2022;603(7900):343-347. doi:10.1038/s41586-022-04470-1
LibreCat: https://research-explorer.ista.ac.at/record/15136
DOI: 10.1038/s41586-022-04470-1
PMID: 35236982

Schwartz EA, Bravo JPK, Macias LA, et al. Assembly of multi-subunit fusion proteins into the RNA-targeting type III-D CRISPR-Cas effector complex. bioRxiv. doi:10.1101/2022.06.13.496011
LibreCat: https://research-explorer.ista.ac.at/record/17116
DOI: 10.1101/2022.06.13.496011

O’Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade. bioRxiv. 2022. doi:10.1101/2022.06.15.496202
LibreCat: https://research-explorer.ista.ac.at/record/17115
DOI: 10.1101/2022.06.15.496202

Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson RN, Taylor DW. Large-scale structural rearrangements unleash indiscriminate nuclease activity of CRISPR-Ca. bioRxiv. 2022. doi:10.1101/2022.06.13.495754
LibreCat: https://research-explorer.ista.ac.at/record/17117
DOI: 10.1101/2022.06.13.495754

Zhou Y, Bravo JPK, Taylor HN, et al. Structure of a type IV CRISPR-Cas ribonucleoprotein complex. iScience. 2021;24(3). doi:10.1016/j.isci.2021.102201
LibreCat: https://research-explorer.ista.ac.at/record/15141
DOI: 10.1016/j.isci.2021.102201
PMID: 33733066

Geiger F, Acker J, Papa G, et al. Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses. The EMBO Journal. 2021;40(21). doi:10.15252/embj.2021107711
LibreCat: https://research-explorer.ista.ac.at/record/15138
DOI: 10.15252/embj.2021107711
PMID: 34524703

Steens JA, Zhu Y, Taylor DW, et al. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. Nature Communications. 2021;12. doi:10.1038/s41467-021-25337-5
LibreCat: https://research-explorer.ista.ac.at/record/15137
DOI: 10.1038/s41467-021-25337-5
PMID: 34413302

Bravo JPK, Bartnik K, Venditti L, et al. Structural basis of rotavirus RNA chaperone displacement and RNA annealing. Proceedings of the National Academy of Sciences. 2021;118(41). doi:10.1073/pnas.2100198118
LibreCat: https://research-explorer.ista.ac.at/record/15139
DOI: 10.1073/pnas.2100198118
PMID: 34615715