[{"day":"01","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","volume":40,"issue":"4","quality_controlled":"1","article_type":"original","oa":1,"year":"2021","author":[{"id":"4DD40360-F248-11E8-B48F-1D18A9856A87","first_name":"Georg","last_name":"Sperl","full_name":"Sperl, Georg"},{"full_name":"Narain, Rahul","last_name":"Narain","first_name":"Rahul"},{"orcid":"0000-0001-6646-5546","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","first_name":"Christopher J","last_name":"Wojtan","full_name":"Wojtan, Christopher J"}],"date_updated":"2026-04-16T08:21:26Z","acknowledged_ssus":[{"_id":"ScienComp"}],"scopus_import":"1","ec_funded":1,"publisher":"Association for Computing Machinery","status":"public","publication":"ACM Transactions on Graphics","article_number":"168","citation":{"ista":"Sperl G, Narain R, Wojtan C. 2021. Mechanics-aware deformation of yarn pattern geometry. ACM Transactions on Graphics. 40(4), 168.","short":"G. Sperl, R. Narain, C. Wojtan, ACM Transactions on Graphics 40 (2021).","chicago":"Sperl, Georg, Rahul Narain, and Chris Wojtan. “Mechanics-Aware Deformation of Yarn Pattern Geometry.” <i>ACM Transactions on Graphics</i>. Association for Computing Machinery, 2021. <a href=\"https://doi.org/10.1145/3450626.3459816\">https://doi.org/10.1145/3450626.3459816</a>.","mla":"Sperl, Georg, et al. “Mechanics-Aware Deformation of Yarn Pattern Geometry.” <i>ACM Transactions on Graphics</i>, vol. 40, no. 4, 168, Association for Computing Machinery, 2021, doi:<a href=\"https://doi.org/10.1145/3450626.3459816\">10.1145/3450626.3459816</a>.","apa":"Sperl, G., Narain, R., &#38; Wojtan, C. (2021). Mechanics-aware deformation of yarn pattern geometry. <i>ACM Transactions on Graphics</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3450626.3459816\">https://doi.org/10.1145/3450626.3459816</a>","ama":"Sperl G, Narain R, Wojtan C. Mechanics-aware deformation of yarn pattern geometry. <i>ACM Transactions on Graphics</i>. 2021;40(4). doi:<a href=\"https://doi.org/10.1145/3450626.3459816\">10.1145/3450626.3459816</a>","ieee":"G. Sperl, R. Narain, and C. Wojtan, “Mechanics-aware deformation of yarn pattern geometry,” <i>ACM Transactions on Graphics</i>, vol. 40, no. 4. Association for Computing Machinery, 2021."},"department":[{"_id":"GradSch"},{"_id":"ChWo"}],"title":"Mechanics-aware deformation of yarn pattern geometry","main_file_link":[{"url":"https://doi.org/10.1145/3450626.3459816","open_access":"1"}],"article_processing_charge":"Yes (in subscription journal)","doi":"10.1145/3450626.3459816","date_created":"2021-08-08T22:01:27Z","oa_version":"Published Version","abstract":[{"text":"Triangle mesh-based simulations are able to produce satisfying animations of knitted and woven cloth; however, they lack the rich geometric detail of yarn-level simulations. Naive texturing approaches do not consider yarn-level physics, while full yarn-level simulations may become prohibitively expensive for large garments. We propose a method to animate yarn-level cloth geometry on top of an underlying deforming mesh in a mechanics-aware fashion. Using triangle strains to interpolate precomputed yarn geometry, we are able to reproduce effects such as knit loops tightening under stretching. In combination with precomputed mesh animation or real-time mesh simulation, our method is able to animate yarn-level cloth in real-time at large scales.","lang":"eng"}],"type":"journal_article","month":"08","project":[{"call_identifier":"H2020","_id":"2533E772-B435-11E9-9278-68D0E5697425","grant_number":"638176","name":"Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large Scales"}],"external_id":{"isi":["000674930900132"]},"publication_identifier":{"issn":["0730-0301"],"eissn":["1557-7368"]},"acknowledgement":"We wish to thank the anonymous reviewers and the members of the Visual Computing Group at IST Austria for their valuable feedback. We also thank Seddi Labs for providing the garment model with fold-over seams.\r\nThis research was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by Scientific\r\nComputing. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 638176. Rahul Narain is supported by a Pankaj Gupta Young Faculty Fellowship and a gift from Adobe Inc.","_id":"9818","isi":1,"related_material":{"link":[{"url":"https://ist.ac.at/en/news/knitting-virtual-yarn/","relation":"press_release","description":"News on IST Webpage"}],"record":[{"status":"public","relation":"software","id":"9327"},{"status":"public","id":"12358","relation":"dissertation_contains"}]},"date_published":"2021-08-01T00:00:00Z","language":[{"iso":"eng"}],"publication_status":"published","intvolume":"        40"},{"gitlab_commit_id":"6a77e7e22769230ae5f5edaa090fb4b828e57573","oa":1,"abstract":[{"text":"This archive contains the missing sweater mesh animations and displacement models for the code of \"Mechanics-Aware Deformation of Yarn Pattern Geometry\"\r\n\r\nCode Repository: https://git.ist.ac.at/gsperl/MADYPG","lang":"eng"}],"month":"05","file_date_updated":"2021-04-26T09:33:44Z","type":"software","tmp":{"name":"The MIT License","short":"MIT","legal_code_url":"https://opensource.org/licenses/MIT"},"department":[{"_id":"GradSch"},{"_id":"ChWo"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","doi":"10.15479/AT:ISTA:9327","license":"https://opensource.org/licenses/MIT","date_created":"2021-04-16T14:26:19Z","title":"Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data)","gitlab_url":"https://git.ist.ac.at/gsperl/MADYPG","has_accepted_license":"1","file":[{"access_level":"open_access","date_updated":"2021-04-16T14:15:12Z","date_created":"2021-04-16T14:15:12Z","success":1,"checksum":"0324cb519273371708743f3282e7c081","file_size":802586232,"content_type":"application/zip","file_name":"MADYPG_extra_data.zip","creator":"gsperl","file_id":"9328","relation":"main_file"},{"date_created":"2021-04-26T09:33:44Z","access_level":"open_access","date_updated":"2021-04-26T09:33:44Z","file_size":64962865,"content_type":"application/gzip","checksum":"4c224551adf852b136ec21a4e13f0c1b","relation":"main_file","file_id":"9353","creator":"pub-gitlab-bot","file_name":"MADYPG.zip"}],"publisher":"IST Austria","citation":{"mla":"Sperl, Georg, et al. <i>Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data)</i>. IST Austria, 2021, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:9327\">10.15479/AT:ISTA:9327</a>.","ama":"Sperl G, Narain R, Wojtan C. Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data). 2021. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:9327\">10.15479/AT:ISTA:9327</a>","ieee":"G. Sperl, R. Narain, and C. Wojtan, “Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data).” IST Austria, 2021.","apa":"Sperl, G., Narain, R., &#38; Wojtan, C. (2021). Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data). IST Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:9327\">https://doi.org/10.15479/AT:ISTA:9327</a>","chicago":"Sperl, Georg, Rahul Narain, and Chris Wojtan. “Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data).” IST Austria, 2021. <a href=\"https://doi.org/10.15479/AT:ISTA:9327\">https://doi.org/10.15479/AT:ISTA:9327</a>.","short":"G. Sperl, R. Narain, C. Wojtan, (2021).","ista":"Sperl G, Narain R, Wojtan C. 2021. Mechanics-Aware Deformation of Yarn Pattern Geometry (Additional Animation/Model Data), IST Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:9327\">10.15479/AT:ISTA:9327</a>."},"ddc":["005"],"status":"public","year":"2021","author":[{"id":"4DD40360-F248-11E8-B48F-1D18A9856A87","full_name":"Sperl, Georg","last_name":"Sperl","first_name":"Georg"},{"last_name":"Narain","first_name":"Rahul","full_name":"Narain, Rahul"},{"last_name":"Wojtan","first_name":"Christopher J","full_name":"Wojtan, Christopher J","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6646-5546"}],"_id":"9327","related_material":{"record":[{"status":"public","id":"9818","relation":"used_for_analysis_in"}]},"date_published":"2021-05-01T00:00:00Z","date_updated":"2026-04-16T08:21:25Z"},{"_id":"9826","date_published":"2021-05-11T00:00:00Z","language":[{"iso":"eng"}],"intvolume":"     12704","publication_status":"published","department":[{"_id":"KrPi"},{"_id":"GradSch"}],"title":"Inverse-Sybil attacks in automated contact tracing","date_created":"2021-08-08T22:01:30Z","oa_version":"Submitted Version","doi":"10.1007/978-3-030-75539-3_17","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2020/670"}],"article_processing_charge":"No","type":"conference","month":"05","abstract":[{"text":"Automated contract tracing aims at supporting manual contact tracing during pandemics by alerting users of encounters with infected people. There are currently many proposals for protocols (like the “decentralized” DP-3T and PACT or the “centralized” ROBERT and DESIRE) to be run on mobile phones, where the basic idea is to regularly broadcast (using low energy Bluetooth) some values, and at the same time store (a function of) incoming messages broadcasted by users in their proximity. In the existing proposals one can trigger false positives on a massive scale by an “inverse-Sybil” attack, where a large number of devices (malicious users or hacked phones) pretend to be the same user, such that later, just a single person needs to be diagnosed (and allowed to upload) to trigger an alert for all users who were in proximity to any of this large group of devices.\r\n\r\nWe propose the first protocols that do not succumb to such attacks assuming the devices involved in the attack do not constantly communicate, which we observe is a necessary assumption. The high level idea of the protocols is to derive the values to be broadcasted by a hash chain, so that two (or more) devices who want to launch an inverse-Sybil attack will not be able to connect their respective chains and thus only one of them will be able to upload. Our protocols also achieve security against replay, belated replay, and one of them even against relay attacks.","lang":"eng"}],"project":[{"call_identifier":"H2020","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","name":"International IST Doctoral Program"},{"_id":"258AA5B2-B435-11E9-9278-68D0E5697425","name":"Teaching Old Crypto New Tricks","grant_number":"682815","call_identifier":"H2020"}],"publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783030755386"]},"acknowledgement":"Guillermo Pascual-Perez and Michelle Yeo were funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska–Curie Grant Agreement No. 665385; the remaining contributors to this project have received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (682815 - TOCNeT).","corr_author":"1","author":[{"id":"D33D2B18-E445-11E9-ABB7-15F4E5697425","orcid":"0000-0002-7553-6606","full_name":"Auerbach, Benedikt","last_name":"Auerbach","first_name":"Benedikt"},{"last_name":"Chakraborty","first_name":"Suvradip","full_name":"Chakraborty, Suvradip","id":"B9CD0494-D033-11E9-B219-A439E6697425"},{"full_name":"Klein, Karen","first_name":"Karen","last_name":"Klein","id":"3E83A2F8-F248-11E8-B48F-1D18A9856A87"},{"id":"2D7ABD02-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8630-415X","full_name":"Pascual Perez, Guillermo","first_name":"Guillermo","last_name":"Pascual Perez"},{"id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654","full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z","last_name":"Pietrzak"},{"last_name":"Walter","first_name":"Michael","full_name":"Walter, Michael","id":"488F98B0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3186-2482"},{"full_name":"Yeo, Michelle X","last_name":"Yeo","first_name":"Michelle X","id":"2D82B818-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0001-3676-4809"}],"year":"2021","date_updated":"2026-04-16T09:28:46Z","publisher":"Springer Nature","conference":{"location":"Virtual Event","name":"CT-RSA: Cryptographers’ Track at the RSA Conference","end_date":"2021-05-20","start_date":"2021-05-17"},"ec_funded":1,"scopus_import":"1","status":"public","publication":"Topics in Cryptology – CT-RSA 2021","citation":{"ista":"Auerbach B, Chakraborty S, Klein K, Pascual Perez G, Pietrzak KZ, Walter M, Yeo MX. 2021. Inverse-Sybil attacks in automated contact tracing. Topics in Cryptology – CT-RSA 2021. CT-RSA: Cryptographers’ Track at the RSA Conference, LNCS, vol. 12704, 399–421.","short":"B. Auerbach, S. Chakraborty, K. Klein, G. Pascual Perez, K.Z. Pietrzak, M. Walter, M.X. Yeo, in:, Topics in Cryptology – CT-RSA 2021, Springer Nature, 2021, pp. 399–421.","chicago":"Auerbach, Benedikt, Suvradip Chakraborty, Karen Klein, Guillermo Pascual Perez, Krzysztof Z Pietrzak, Michael Walter, and Michelle X Yeo. “Inverse-Sybil Attacks in Automated Contact Tracing.” In <i>Topics in Cryptology – CT-RSA 2021</i>, 12704:399–421. Springer Nature, 2021. <a href=\"https://doi.org/10.1007/978-3-030-75539-3_17\">https://doi.org/10.1007/978-3-030-75539-3_17</a>.","ieee":"B. Auerbach <i>et al.</i>, “Inverse-Sybil attacks in automated contact tracing,” in <i>Topics in Cryptology – CT-RSA 2021</i>, Virtual Event, 2021, vol. 12704, pp. 399–421.","ama":"Auerbach B, Chakraborty S, Klein K, et al. Inverse-Sybil attacks in automated contact tracing. In: <i>Topics in Cryptology – CT-RSA 2021</i>. Vol 12704. Springer Nature; 2021:399-421. doi:<a href=\"https://doi.org/10.1007/978-3-030-75539-3_17\">10.1007/978-3-030-75539-3_17</a>","mla":"Auerbach, Benedikt, et al. “Inverse-Sybil Attacks in Automated Contact Tracing.” <i>Topics in Cryptology – CT-RSA 2021</i>, vol. 12704, Springer Nature, 2021, pp. 399–421, doi:<a href=\"https://doi.org/10.1007/978-3-030-75539-3_17\">10.1007/978-3-030-75539-3_17</a>.","apa":"Auerbach, B., Chakraborty, S., Klein, K., Pascual Perez, G., Pietrzak, K. Z., Walter, M., &#38; Yeo, M. X. (2021). Inverse-Sybil attacks in automated contact tracing. In <i>Topics in Cryptology – CT-RSA 2021</i> (Vol. 12704, pp. 399–421). Virtual Event: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-75539-3_17\">https://doi.org/10.1007/978-3-030-75539-3_17</a>"},"page":"399-421","day":"11","alternative_title":["LNCS"],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","volume":12704,"quality_controlled":"1","oa":1},{"project":[{"grant_number":"682815","name":"Teaching Old Crypto New Tricks","_id":"258AA5B2-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"abstract":[{"lang":"eng","text":"Many security definitions come in two flavors: a stronger “adaptive” flavor, where the adversary can arbitrarily make various choices during the course of the attack, and a weaker “selective” flavor where the adversary must commit to some or all of their choices a-priori. For example, in the context of identity-based encryption, selective security requires the adversary to decide on the identity of the attacked party at the very beginning of the game whereas adaptive security allows the attacker to first see the master public key and some secret keys before making this choice. Often, it appears to be much easier to achieve selective security than it is to achieve adaptive security. A series of several recent works shows how to cleverly achieve adaptive security in several such scenarios including generalized selective decryption [Pan07][FJP15], constrained PRFs [FKPR14], and Yao’s garbled circuits [JW16]. Although the above works expressed vague intuition that they share a common technique, the connection was never made precise. In this work we present a new framework (published at Crypto ’17 [JKK+17a]) that connects all of these works and allows us to present them in a unified and simplified fashion. Having the framework in place, we show how to achieve adaptive security for proxy re-encryption schemes (published at PKC ’19 [FKKP19]) and provide the first adaptive security proofs for continuous group key agreement protocols (published at S&P ’21 [KPW+21]). Questioning optimality of our framework, we then show that currently used proof techniques cannot lead to significantly better security guarantees for \"graph-building\" games (published at TCC ’21 [KKPW21a]). These games cover generalized selective decryption, as well as the security of prominent constructions for constrained PRFs, continuous group key agreement, and proxy re-encryption. Finally, we revisit the adaptive security of Yao’s garbled circuits and extend the analysis of Jafargholi and Wichs in two directions: While they prove adaptive security only for a modified construction with increased online complexity, we provide the first positive results for the original construction by Yao (published at TCC ’21 [KKP21a]). On the negative side, we prove that the results of Jafargholi and Wichs are essentially optimal by showing that no black-box reduction can provide a significantly better security bound (published at Crypto ’21 [KKPW21c])."}],"month":"09","type":"dissertation","file_date_updated":"2022-03-10T12:15:18Z","corr_author":"1","acknowledgement":"I want to acknowledge the funding by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (682815 - TOCNeT).\r\n","publication_identifier":{"issn":["2663-337X"]},"department":[{"_id":"GradSch"},{"_id":"KrPi"}],"degree_awarded":"PhD","article_processing_charge":"No","doi":"10.15479/at:ista:10035","oa_version":"Published Version","date_created":"2021-09-23T07:31:44Z","title":"On the adaptive security of graph-based games","language":[{"iso":"eng"}],"publication_status":"published","related_material":{"record":[{"status":"public","id":"10044","relation":"part_of_dissertation"},{"status":"public","id":"10048","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"10041"},{"id":"10049","relation":"part_of_dissertation","status":"public"},{"relation":"part_of_dissertation","id":"637","status":"public"},{"relation":"part_of_dissertation","id":"6430","status":"public"}]},"_id":"10035","date_published":"2021-09-23T00:00:00Z","oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","alternative_title":["ISTA Thesis"],"day":"23","supervisor":[{"first_name":"Krzysztof Z","last_name":"Pietrzak","full_name":"Pietrzak, Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654"}],"has_accepted_license":"1","ec_funded":1,"publisher":"Institute of Science and Technology Austria","file":[{"access_level":"open_access","date_updated":"2021-10-04T12:22:33Z","date_created":"2021-10-04T12:22:33Z","success":1,"file_size":2104726,"content_type":"application/pdf","checksum":"73a44345c683e81f3e765efbf86fdcc5","creator":"cchlebak","file_name":"thesis_pdfa.pdf","relation":"main_file","file_id":"10082"},{"date_updated":"2022-03-10T12:15:18Z","access_level":"closed","date_created":"2021-10-05T07:04:37Z","file_size":9538359,"checksum":"7b80df30a0e686c3ef6a56d4e1c59e29","content_type":"application/x-zip-compressed","file_name":"thesis_final (1).zip","creator":"cchlebak","file_id":"10085","relation":"source_file"}],"citation":{"short":"K. Klein, On the Adaptive Security of Graph-Based Games, Institute of Science and Technology Austria, 2021.","chicago":"Klein, Karen. “On the Adaptive Security of Graph-Based Games.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10035\">https://doi.org/10.15479/at:ista:10035</a>.","ista":"Klein K. 2021. On the adaptive security of graph-based games. Institute of Science and Technology Austria.","ama":"Klein K. On the adaptive security of graph-based games. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10035\">10.15479/at:ista:10035</a>","ieee":"K. Klein, “On the adaptive security of graph-based games,” Institute of Science and Technology Austria, 2021.","mla":"Klein, Karen. <i>On the Adaptive Security of Graph-Based Games</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10035\">10.15479/at:ista:10035</a>.","apa":"Klein, K. (2021). <i>On the adaptive security of graph-based games</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10035\">https://doi.org/10.15479/at:ista:10035</a>"},"page":"276","ddc":["519"],"status":"public","year":"2021","author":[{"id":"3E83A2F8-F248-11E8-B48F-1D18A9856A87","first_name":"Karen","last_name":"Klein","full_name":"Klein, Karen"}],"date_updated":"2026-04-16T09:52:03Z"},{"publication_status":"published","intvolume":"         5","language":[{"iso":"eng"}],"date_published":"2021-07-01T00:00:00Z","_id":"9760","related_material":{"record":[{"relation":"dissertation_contains","id":"14622","status":"public"}]},"isi":1,"corr_author":"1","acknowledgement":"We would like to thank D. Abanin and R. Medina for fruitful discussions and A. Smith and I. Kim for valuable feedback on the manuscript. We acknowledge support by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899).","publication_identifier":{"eissn":["2521-327X"]},"project":[{"name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","grant_number":"850899","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","call_identifier":"H2020"}],"external_id":{"isi":["000669830600001"],"arxiv":["2101.05742"]},"abstract":[{"text":"The quantum approximate optimization algorithm (QAOA) is a prospective near-term quantum algorithm due to its modest circuit depth and promising benchmarks. However, an external parameter optimization required in the QAOA could become a performance bottleneck. This motivates studies of the optimization landscape and search for heuristic ways of parameter initialization. In this work we visualize the optimization landscape of the QAOA applied to the MaxCut problem on random graphs, demonstrating that random initialization of the QAOA is prone to converging to local minima with suboptimal performance. We introduce the initialization of QAOA parameters based on the Trotterized quantum annealing (TQA) protocol, parameterized by the Trotter time step. We find that the TQA initialization allows to circumvent\r\nthe issue of false minima for a broad range of time steps, yielding the same performance as the best result out of an exponentially scaling number of random initializations. Moreover, we demonstrate that the optimal value of the time step coincides with the point of proliferation of Trotter errors in quantum annealing. Our results suggest practical ways of initializing QAOA protocols on near-term quantum devices and reveal new connections between QAOA and quantum annealing.","lang":"eng"}],"type":"journal_article","file_date_updated":"2021-08-06T06:44:31Z","arxiv":1,"month":"07","article_processing_charge":"Yes","date_created":"2021-08-01T22:01:21Z","oa_version":"Published Version","doi":"10.22331/Q-2021-07-01-491","title":"Quantum annealing initialization of the quantum approximate optimization algorithm","department":[{"_id":"GradSch"},{"_id":"MaSe"}],"article_number":"491","citation":{"short":"S. Sack, M. Serbyn, Quantum 5 (2021).","chicago":"Sack, Stefan, and Maksym Serbyn. “Quantum Annealing Initialization of the Quantum Approximate Optimization Algorithm.” <i>Quantum</i>. Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften, 2021. <a href=\"https://doi.org/10.22331/Q-2021-07-01-491\">https://doi.org/10.22331/Q-2021-07-01-491</a>.","ista":"Sack S, Serbyn M. 2021. Quantum annealing initialization of the quantum approximate optimization algorithm. Quantum. 5, 491.","apa":"Sack, S., &#38; Serbyn, M. (2021). Quantum annealing initialization of the quantum approximate optimization algorithm. <i>Quantum</i>. Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften. <a href=\"https://doi.org/10.22331/Q-2021-07-01-491\">https://doi.org/10.22331/Q-2021-07-01-491</a>","mla":"Sack, Stefan, and Maksym Serbyn. “Quantum Annealing Initialization of the Quantum Approximate Optimization Algorithm.” <i>Quantum</i>, vol. 5, 491, Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften, 2021, doi:<a href=\"https://doi.org/10.22331/Q-2021-07-01-491\">10.22331/Q-2021-07-01-491</a>.","ieee":"S. Sack and M. Serbyn, “Quantum annealing initialization of the quantum approximate optimization algorithm,” <i>Quantum</i>, vol. 5. Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften, 2021.","ama":"Sack S, Serbyn M. Quantum annealing initialization of the quantum approximate optimization algorithm. <i>Quantum</i>. 2021;5. doi:<a href=\"https://doi.org/10.22331/Q-2021-07-01-491\">10.22331/Q-2021-07-01-491</a>"},"ddc":["530"],"publication":"Quantum","status":"public","ec_funded":1,"has_accepted_license":"1","scopus_import":"1","publisher":"Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften","file":[{"file_id":"9774","relation":"main_file","file_name":"2021_Quantum_Sack.pdf","creator":"cchlebak","date_created":"2021-08-06T06:44:31Z","access_level":"open_access","date_updated":"2021-08-06T06:44:31Z","file_size":2312482,"content_type":"application/pdf","checksum":"9706c2bb8e748e9b5b138381995a7f6f"}],"date_updated":"2026-04-29T22:30:23Z","year":"2021","author":[{"last_name":"Sack","first_name":"Stefan","full_name":"Sack, Stefan","orcid":"0000-0001-5400-8508","id":"dd622248-f6e0-11ea-865d-ce382a1c81a5"},{"full_name":"Serbyn, Maksym","first_name":"Maksym","last_name":"Serbyn","orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"quality_controlled":"1","article_type":"original","volume":5,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01"},{"acknowledgement":"We thank Peter Baracskay, Karola Kaefer and Hugo Malagon-Vina for the acquisition of the data. We thank Federico Stella for comments on an earlier version of the manuscript. MN was supported by European Union Horizon 2020 grant 665385, JC was supported by European Research Council consolidator grant 281511, GT was supported by the Austrian Science Fund (FWF) grant P34015, CS was supported by an IST fellow grant, National Institute of Mental Health Award 1R01MH125571-01, by the National Science Foundation under NSF Award No. 1922658 and a Google faculty award.","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"type":"preprint","month":"09","abstract":[{"lang":"eng","text":"Although much is known about how single neurons in the hippocampus represent an animal’s position, how cell-cell interactions contribute to spatial coding remains poorly understood. Using a novel statistical estimator and theoretical modeling, both developed in the framework of maximum entropy models, we reveal highly structured cell-to-cell interactions whose statistics depend on familiar vs. novel environment. In both conditions the circuit interactions optimize the encoding of spatial information, but for regimes that differ in the signal-to-noise ratio of their spatial inputs. Moreover, the topology of the interactions facilitates linear decodability, making the information easy to read out by downstream circuits. These findings suggest that the efficient coding hypothesis is not applicable only to individual neuron properties in the sensory periphery, but also to neural interactions in the central brain."}],"oa":1,"project":[{"call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","name":"International IST Postdoc Fellowship Programme"},{"call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FP7","grant_number":"281511","name":"Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex","_id":"257A4776-B435-11E9-9278-68D0E5697425"},{"name":"Efficient coding with biophysical realism","grant_number":"P34015","_id":"626c45b5-2b32-11ec-9570-e509828c1ba6"}],"title":"The structure of hippocampal CA1 interactions optimizes spatial coding across experience","date_created":"2021-10-04T06:23:34Z","oa_version":"Preprint","doi":"10.1101/2021.09.28.460602","main_file_link":[{"open_access":"1","url":"https://www.biorxiv.org/content/10.1101/2021.09.28.460602"}],"article_processing_charge":"No","day":"29","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"GradSch"},{"_id":"JoCs"},{"_id":"GaTk"}],"status":"public","publication":"bioRxiv","publication_status":"draft","citation":{"chicago":"Nardin, Michele, Jozsef L Csicsvari, Gašper Tkačik, and Cristina Savin. “The Structure of Hippocampal CA1 Interactions Optimizes Spatial Coding across Experience.” <i>BioRxiv</i>. Cold Spring Harbor Laboratory, n.d. <a href=\"https://doi.org/10.1101/2021.09.28.460602\">https://doi.org/10.1101/2021.09.28.460602</a>.","ista":"Nardin M, Csicsvari JL, Tkačik G, Savin C. The structure of hippocampal CA1 interactions optimizes spatial coding across experience. bioRxiv, <a href=\"https://doi.org/10.1101/2021.09.28.460602\">10.1101/2021.09.28.460602</a>.","short":"M. Nardin, J.L. Csicsvari, G. Tkačik, C. Savin, BioRxiv (n.d.).","apa":"Nardin, M., Csicsvari, J. L., Tkačik, G., &#38; Savin, C. (n.d.). The structure of hippocampal CA1 interactions optimizes spatial coding across experience. <i>bioRxiv</i>. Cold Spring Harbor Laboratory. <a href=\"https://doi.org/10.1101/2021.09.28.460602\">https://doi.org/10.1101/2021.09.28.460602</a>","ieee":"M. Nardin, J. L. Csicsvari, G. Tkačik, and C. Savin, “The structure of hippocampal CA1 interactions optimizes spatial coding across experience,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory.","ama":"Nardin M, Csicsvari JL, Tkačik G, Savin C. The structure of hippocampal CA1 interactions optimizes spatial coding across experience. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2021.09.28.460602\">10.1101/2021.09.28.460602</a>","mla":"Nardin, Michele, et al. “The Structure of Hippocampal CA1 Interactions Optimizes Spatial Coding across Experience.” <i>BioRxiv</i>, Cold Spring Harbor Laboratory, doi:<a href=\"https://doi.org/10.1101/2021.09.28.460602\">10.1101/2021.09.28.460602</a>."},"publisher":"Cold Spring Harbor Laboratory","ec_funded":1,"language":[{"iso":"eng"}],"date_updated":"2026-04-29T22:30:34Z","date_published":"2021-09-29T00:00:00Z","related_material":{"record":[{"id":"14656","relation":"later_version","status":"public"},{"id":"11932","relation":"dissertation_contains","status":"public"}]},"_id":"10077","author":[{"orcid":"0000-0001-8849-6570","id":"30BD0376-F248-11E8-B48F-1D18A9856A87","full_name":"Nardin, Michele","last_name":"Nardin","first_name":"Michele"},{"id":"3FA14672-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5193-4036","first_name":"Jozsef L","last_name":"Csicsvari","full_name":"Csicsvari, Jozsef L"},{"first_name":"Gašper","last_name":"Tkačik","full_name":"Tkačik, Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6699-1455"},{"full_name":"Savin, Cristina","first_name":"Cristina","last_name":"Savin","id":"3933349E-F248-11E8-B48F-1D18A9856A87"}],"year":"2021"},{"publication_identifier":{"issn":["2663-337X"]},"corr_author":"1","abstract":[{"text":"Indirect reciprocity in evolutionary game theory is a prominent mechanism for explaining the evolution of cooperation among unrelated individuals. In contrast to direct reciprocity, which is based on individuals meeting repeatedly, and conditionally cooperating by using their own experiences, indirect reciprocity is based on individuals’ reputations. If a player helps another, this increases the helper’s public standing, benefitting them in the future. This lets cooperation in the population emerge without individuals having to meet more than once. While the two modes of reciprocity are intertwined, they are difficult to compare. Thus, they are usually studied in isolation. Direct reciprocity can maintain cooperation with simple strategies, and is robust against noise even when players do not remember more\r\nthan their partner’s last action. Meanwhile, indirect reciprocity requires its successful strategies, or social norms, to be more complex. Exhaustive search previously identified eight such norms, called the “leading eight”, which excel at maintaining cooperation. However, as the first result of this thesis, we show that the leading eight break down once we remove the fundamental assumption that information is synchronized and public, such that everyone agrees on reputations. Once we consider a more realistic scenario of imperfect information, where reputations are private, and individuals occasionally misinterpret or miss observations, the leading eight do not promote cooperation anymore. Instead, minor initial disagreements can proliferate, fragmenting populations into subgroups. In a next step, we consider ways to mitigate this issue. We first explore whether introducing “generosity” can stabilize cooperation when players use the leading eight strategies in noisy environments. This approach of modifying strategies to include probabilistic elements for coping with errors is known to work well in direct reciprocity. However, as we show here, it fails for the more complex norms of indirect reciprocity. Imperfect information still prevents cooperation from evolving. On the other hand, we succeeded to show in this thesis that modifying the leading eight to use “quantitative assessment”, i.e. tracking reputation scores on a scale beyond good and bad, and making overall judgments of others based on a threshold, is highly successful, even when noise increases in the environment. Cooperation can flourish when reputations\r\nare more nuanced, and players have a broader understanding what it means to be “good.” Finally, we present a single theoretical framework that unites the two modes of reciprocity despite their differences. Within this framework, we identify a novel simple and successful strategy for indirect reciprocity, which can cope with noisy environments and has an analogue in direct reciprocity. We can also analyze decision making when different sources of information are available. Our results help highlight that for sustaining cooperation, already the most simple rules of reciprocity can be sufficient.","lang":"eng"}],"file_date_updated":"2022-12-20T23:30:08Z","month":"11","type":"dissertation","project":[{"call_identifier":"FP7","_id":"2581B60A-B435-11E9-9278-68D0E5697425","name":"Quantitative Graph Games: Theory and Applications","grant_number":"279307"},{"call_identifier":"H2020","name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E"},{"call_identifier":"FWF","name":"Formal methods for the design and analysis of complex systems","grant_number":"Z211","_id":"25F42A32-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FWF","_id":"2584A770-B435-11E9-9278-68D0E5697425","name":"Modern Graph Algorithmic Techniques in Formal Verification","grant_number":"P 23499-N23"},{"call_identifier":"FWF","name":"Rigorous Systems Engineering","grant_number":"S 11407_N23","_id":"25832EC2-B435-11E9-9278-68D0E5697425"}],"title":"Evolution of cooperation via (in)direct reciprocity under imperfect information","article_processing_charge":"No","oa_version":"Published Version","date_created":"2021-11-15T17:12:57Z","doi":"10.15479/at:ista:10293","department":[{"_id":"GradSch"},{"_id":"KrCh"}],"degree_awarded":"PhD","publication_status":"published","language":[{"iso":"eng"}],"date_published":"2021-11-17T00:00:00Z","_id":"10293","related_material":{"record":[{"relation":"part_of_dissertation","id":"9997","status":"public"},{"id":"9402","relation":"part_of_dissertation","status":"public"},{"status":"public","id":"2","relation":"part_of_dissertation"}]},"oa":1,"supervisor":[{"full_name":"Chatterjee, Krishnendu","last_name":"Chatterjee","first_name":"Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X"}],"alternative_title":["ISTA Thesis"],"day":"17","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","status":"public","page":"171","citation":{"apa":"Schmid, L. (2021). <i>Evolution of cooperation via (in)direct reciprocity under imperfect information</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10293\">https://doi.org/10.15479/at:ista:10293</a>","mla":"Schmid, Laura. <i>Evolution of Cooperation via (in)Direct Reciprocity under Imperfect Information</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10293\">10.15479/at:ista:10293</a>.","ama":"Schmid L. Evolution of cooperation via (in)direct reciprocity under imperfect information. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10293\">10.15479/at:ista:10293</a>","ieee":"L. Schmid, “Evolution of cooperation via (in)direct reciprocity under imperfect information,” Institute of Science and Technology Austria, 2021.","short":"L. Schmid, Evolution of Cooperation via (in)Direct Reciprocity under Imperfect Information, Institute of Science and Technology Austria, 2021.","chicago":"Schmid, Laura. “Evolution of Cooperation via (in)Direct Reciprocity under Imperfect Information.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10293\">https://doi.org/10.15479/at:ista:10293</a>.","ista":"Schmid L. 2021. Evolution of cooperation via (in)direct reciprocity under imperfect information. Institute of Science and Technology Austria."},"ddc":["519","576"],"has_accepted_license":"1","ec_funded":1,"file":[{"file_id":"10305","relation":"source_file","file_name":"submission_new.zip","creator":"lschmid","content_type":"application/zip","file_size":29703124,"checksum":"86a05b430756ca12ae8107b6e6f3c1e5","embargo_to":"open_access","date_created":"2021-11-18T12:41:46Z","access_level":"closed","date_updated":"2022-12-20T23:30:08Z"},{"creator":"lschmid","file_name":"thesis_new_upload.pdf","relation":"main_file","embargo":"2022-10-18","file_id":"10306","date_updated":"2022-12-20T23:30:08Z","access_level":"open_access","date_created":"2021-11-18T12:59:15Z","checksum":"d940af042e94660c6b6a7b4f0b184d47","content_type":"application/pdf","file_size":8320985}],"publisher":"Institute of Science and Technology Austria","date_updated":"2026-04-08T07:11:20Z","year":"2021","author":[{"id":"38B437DE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6978-7329","full_name":"Schmid, Laura","last_name":"Schmid","first_name":"Laura"}]},{"file":[{"date_updated":"2021-09-15T22:30:26Z","access_level":"closed","embargo_to":"open_access","date_created":"2021-09-09T07:29:48Z","checksum":"c763064adaa720e16066c1a4f9682bbb","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":25179004,"creator":"lhoermaye","file_name":"Thesis_vupload.docx","relation":"source_file","file_id":"9993"},{"embargo":"2021-09-09","relation":"main_file","file_id":"9996","creator":"lhoermaye","file_name":"Thesis_vfinal_pdfa.pdf","content_type":"application/pdf","checksum":"53911b06e93d7cdbbf4c7f4c162fa70f","file_size":6246900,"date_created":"2021-09-09T14:25:08Z","date_updated":"2021-09-15T22:30:26Z","access_level":"open_access"}],"publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","ec_funded":1,"status":"public","page":"168","ddc":["575"],"citation":{"ista":"Hörmayer L. 2021. Wound healing in the Arabidopsis root meristem. Institute of Science and Technology Austria.","chicago":"Hörmayer, Lukas. “Wound Healing in the Arabidopsis Root Meristem.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:9992\">https://doi.org/10.15479/at:ista:9992</a>.","short":"L. Hörmayer, Wound Healing in the Arabidopsis Root Meristem, Institute of Science and Technology Austria, 2021.","ama":"Hörmayer L. Wound healing in the Arabidopsis root meristem. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:9992\">10.15479/at:ista:9992</a>","mla":"Hörmayer, Lukas. <i>Wound Healing in the Arabidopsis Root Meristem</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:9992\">10.15479/at:ista:9992</a>.","apa":"Hörmayer, L. (2021). <i>Wound healing in the Arabidopsis root meristem</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:9992\">https://doi.org/10.15479/at:ista:9992</a>","ieee":"L. Hörmayer, “Wound healing in the Arabidopsis root meristem,” Institute of Science and Technology Austria, 2021."},"author":[{"id":"2EEE7A2A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8295-2926","last_name":"Hörmayer","first_name":"Lukas","full_name":"Hörmayer, Lukas"}],"year":"2021","date_updated":"2026-04-08T07:11:47Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"oa":1,"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"day":"13","alternative_title":["ISTA Thesis"],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","supervisor":[{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","first_name":"Jiří","last_name":"Friml"}],"language":[{"iso":"eng"}],"publication_status":"published","_id":"9992","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"6943"},{"relation":"part_of_dissertation","id":"8002","status":"public"},{"id":"6351","relation":"part_of_dissertation","status":"public"}]},"date_published":"2021-09-13T00:00:00Z","file_date_updated":"2021-09-15T22:30:26Z","type":"dissertation","month":"09","abstract":[{"lang":"eng","text":"Blood – this is what animals use to heal wounds fast and efficient. Plants do not have blood circulation and their cells cannot move. However, plants have evolved remarkable capacities to regenerate tissues and organs preventing further damage. In my PhD research, I studied the wound healing in the Arabidopsis root. I used a UV laser to ablate single cells in the root tip and observed the consequent wound healing. Interestingly, the inner adjacent cells induced a\r\ndivision plane switch and subsequently adopted the cell type of the killed cell to replace it. We termed this form of wound healing “restorative divisions”. This initial observation triggered the questions of my PhD studies: How and why do cells orient their division planes, how do they feel the wound and why does this happen only in inner adjacent cells.\r\nFor answering these questions, I used a quite simple experimental setup: 5 day - old seedlings were stained with propidium iodide to visualize cell walls and dead cells; ablation was carried out using a special laser cutter and a confocal microscope. Adaptation of the novel vertical microscope system made it possible to observe wounds in real time. This revealed that restorative divisions occur at increased frequency compared to normal divisions. Additionally,\r\nthe major plant hormone auxin accumulates in wound adjacent cells and drives the expression of the wound-stress responsive transcription factor ERF115. Using this as a marker gene for wound responses, we found that an important part of wound signalling is the sensing of the collapse of the ablated cell. The collapse causes a radical pressure drop, which results in strong tissue deformations. These deformations manifest in an invasion of the now free spot specifically by the inner adjacent cells within seconds, probably because of higher pressure of the inner tissues. Long-term imaging revealed that those deformed cells continuously expand towards the wound hole and that this is crucial for the restorative division. These wound-expanding cells exhibit an abnormal, biphasic polarity of microtubule arrays\r\nbefore the division. Experiments inhibiting cell expansion suggest that it is the biphasic stretching that induces those MT arrays. Adapting the micromanipulator aspiration system from animal scientists at our institute confirmed the hypothesis that stretching influences microtubule stability. In conclusion, this shows that microtubules react to tissue deformation\r\nand this facilitates the observed division plane switch. This puts mechanical cues and tensions at the most prominent position for explaining the growth and wound healing properties of plants. Hence, it shines light onto the importance of understanding mechanical signal transduction. "}],"project":[{"call_identifier":"FWF","name":"RNA-directed DNA methylation in plant development","grant_number":"P29988","_id":"262EF96E-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","_id":"261099A6-B435-11E9-9278-68D0E5697425","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","grant_number":"742985"}],"publication_identifier":{"issn":["2663-337X"]},"corr_author":"1","degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"JiFr"}],"title":"Wound healing in the Arabidopsis root meristem","date_created":"2021-09-09T07:37:20Z","oa_version":"Published Version","doi":"10.15479/at:ista:9992","article_processing_charge":"No"},{"title":"The evolution of indirect reciprocity under action and assessment generosity","article_processing_charge":"Yes","doi":"10.1038/s41598-021-96932-1","oa_version":"Published Version","date_created":"2021-09-11T16:22:02Z","department":[{"_id":"GradSch"},{"_id":"KrCh"}],"publication_identifier":{"eissn":["2045-2322"]},"corr_author":"1","acknowledgement":"This work was supported by the European Research Council CoG 863818 (ForM-SMArt) (to K.C.) and the European Research Council Starting Grant 850529: E-DIRECT (to C.H.). L.S. received additional partial support by the Austrian Science Fund (FWF) under Grant Z211-N23 (Wittgenstein Award).","abstract":[{"text":"Indirect reciprocity is a mechanism for the evolution of cooperation based on social norms. This mechanism requires that individuals in a population observe and judge each other’s behaviors. Individuals with a good reputation are more likely to receive help from others. Previous work suggests that indirect reciprocity is only effective when all relevant information is reliable and publicly available. Otherwise, individuals may disagree on how to assess others, even if they all apply the same social norm. Such disagreements can lead to a breakdown of cooperation. Here we explore whether the predominantly studied ‘leading eight’ social norms of indirect reciprocity can be made more robust by equipping them with an element of generosity. To this end, we distinguish between two kinds of generosity. According to assessment generosity, individuals occasionally assign a good reputation to group members who would usually be regarded as bad. According to action generosity, individuals occasionally cooperate with group members with whom they would usually defect. Using individual-based simulations, we show that the two kinds of generosity have a very different effect on the resulting reputation dynamics. Assessment generosity tends to add to the overall noise and allows defectors to invade. In contrast, a limited amount of action generosity can be beneficial in a few cases. However, even when action generosity is beneficial, the respective simulations do not result in full cooperation. Our results suggest that while generosity can favor cooperation when individuals use the most simple strategies of reciprocity, it is disadvantageous when individuals use more complex social norms.","lang":"eng"}],"month":"08","type":"journal_article","file_date_updated":"2021-09-13T10:31:21Z","project":[{"grant_number":"863818","name":"Formal Methods for Stochastic Models: Algorithms and Applications","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020"},{"call_identifier":"FWF","name":"Formal methods for the design and analysis of complex systems","grant_number":"Z211","_id":"25F42A32-B435-11E9-9278-68D0E5697425"}],"external_id":{"isi":["000692406400018"],"pmid":["34465830"]},"date_published":"2021-08-31T00:00:00Z","_id":"9997","isi":1,"related_material":{"record":[{"status":"public","id":"10293","relation":"dissertation_contains"}]},"keyword":["Multidisciplinary"],"publication_status":"published","intvolume":"        11","pmid":1,"language":[{"iso":"eng"}],"volume":11,"issue":"1","day":"31","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"quality_controlled":"1","article_type":"original","oa":1,"date_updated":"2026-04-29T22:30:37Z","year":"2021","author":[{"last_name":"Schmid","first_name":"Laura","full_name":"Schmid, Laura","id":"38B437DE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6978-7329"},{"full_name":"Shati, Pouya","last_name":"Shati","first_name":"Pouya"},{"full_name":"Hilbe, Christian","first_name":"Christian","last_name":"Hilbe"},{"full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu","last_name":"Chatterjee","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X"}],"status":"public","publication":"Scientific Reports","article_number":"17443","ddc":["003"],"citation":{"ieee":"L. Schmid, P. Shati, C. Hilbe, and K. Chatterjee, “The evolution of indirect reciprocity under action and assessment generosity,” <i>Scientific Reports</i>, vol. 11, no. 1. Springer Nature, 2021.","apa":"Schmid, L., Shati, P., Hilbe, C., &#38; Chatterjee, K. (2021). The evolution of indirect reciprocity under action and assessment generosity. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-021-96932-1\">https://doi.org/10.1038/s41598-021-96932-1</a>","ama":"Schmid L, Shati P, Hilbe C, Chatterjee K. The evolution of indirect reciprocity under action and assessment generosity. <i>Scientific Reports</i>. 2021;11(1). doi:<a href=\"https://doi.org/10.1038/s41598-021-96932-1\">10.1038/s41598-021-96932-1</a>","mla":"Schmid, Laura, et al. “The Evolution of Indirect Reciprocity under Action and Assessment Generosity.” <i>Scientific Reports</i>, vol. 11, no. 1, 17443, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41598-021-96932-1\">10.1038/s41598-021-96932-1</a>.","ista":"Schmid L, Shati P, Hilbe C, Chatterjee K. 2021. The evolution of indirect reciprocity under action and assessment generosity. Scientific Reports. 11(1), 17443.","short":"L. Schmid, P. Shati, C. Hilbe, K. Chatterjee, Scientific Reports 11 (2021).","chicago":"Schmid, Laura, Pouya Shati, Christian Hilbe, and Krishnendu Chatterjee. “The Evolution of Indirect Reciprocity under Action and Assessment Generosity.” <i>Scientific Reports</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41598-021-96932-1\">https://doi.org/10.1038/s41598-021-96932-1</a>."},"scopus_import":"1","has_accepted_license":"1","ec_funded":1,"file":[{"content_type":"application/pdf","file_size":2424943,"checksum":"19df8816cf958b272b85841565c73182","date_created":"2021-09-13T10:31:21Z","success":1,"date_updated":"2021-09-13T10:31:21Z","access_level":"open_access","file_id":"10006","relation":"main_file","file_name":"2021_ScientificReports_Schmid.pdf","creator":"cchlebak"}],"publisher":"Springer Nature"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"13","issue":"10","volume":5,"oa":1,"quality_controlled":"1","article_type":"original","year":"2021","author":[{"id":"38B437DE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6978-7329","last_name":"Schmid","first_name":"Laura","full_name":"Schmid, Laura"},{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu","last_name":"Chatterjee"},{"orcid":"0000-0001-5116-955X","id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","last_name":"Hilbe","first_name":"Christian","full_name":"Hilbe, Christian"},{"first_name":"Martin A.","last_name":"Nowak","full_name":"Nowak, Martin A."}],"date_updated":"2026-04-29T22:30:37Z","ec_funded":1,"scopus_import":"1","has_accepted_license":"1","publisher":"Springer Nature","file":[{"file_id":"14496","relation":"main_file","file_name":"2021_NatureHumanBehaviour_Schmid_accepted.pdf","creator":"dernst","checksum":"34f55e173f90dc1dab731063458ac780","file_size":5232761,"content_type":"application/pdf","success":1,"date_created":"2023-11-07T08:27:23Z","date_updated":"2023-11-07T08:27:23Z","access_level":"open_access"}],"citation":{"ieee":"L. Schmid, K. Chatterjee, C. Hilbe, and M. A. Nowak, “A unified framework of direct and indirect reciprocity,” <i>Nature Human Behaviour</i>, vol. 5, no. 10. Springer Nature, pp. 1292–1302, 2021.","apa":"Schmid, L., Chatterjee, K., Hilbe, C., &#38; Nowak, M. A. (2021). A unified framework of direct and indirect reciprocity. <i>Nature Human Behaviour</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41562-021-01114-8\">https://doi.org/10.1038/s41562-021-01114-8</a>","mla":"Schmid, Laura, et al. “A Unified Framework of Direct and Indirect Reciprocity.” <i>Nature Human Behaviour</i>, vol. 5, no. 10, Springer Nature, 2021, pp. 1292–1302, doi:<a href=\"https://doi.org/10.1038/s41562-021-01114-8\">10.1038/s41562-021-01114-8</a>.","ama":"Schmid L, Chatterjee K, Hilbe C, Nowak MA. A unified framework of direct and indirect reciprocity. <i>Nature Human Behaviour</i>. 2021;5(10):1292–1302. doi:<a href=\"https://doi.org/10.1038/s41562-021-01114-8\">10.1038/s41562-021-01114-8</a>","ista":"Schmid L, Chatterjee K, Hilbe C, Nowak MA. 2021. A unified framework of direct and indirect reciprocity. Nature Human Behaviour. 5(10), 1292–1302.","short":"L. Schmid, K. Chatterjee, C. Hilbe, M.A. Nowak, Nature Human Behaviour 5 (2021) 1292–1302.","chicago":"Schmid, Laura, Krishnendu Chatterjee, Christian Hilbe, and Martin A. Nowak. “A Unified Framework of Direct and Indirect Reciprocity.” <i>Nature Human Behaviour</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41562-021-01114-8\">https://doi.org/10.1038/s41562-021-01114-8</a>."},"page":"1292–1302","ddc":["000"],"publication":"Nature Human Behaviour","status":"public","department":[{"_id":"KrCh"},{"_id":"GradSch"}],"article_processing_charge":"No","oa_version":"Submitted Version","date_created":"2021-05-18T16:56:57Z","doi":"10.1038/s41562-021-01114-8","title":"A unified framework of direct and indirect reciprocity","project":[{"call_identifier":"H2020","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818"},{"_id":"2581B60A-B435-11E9-9278-68D0E5697425","grant_number":"279307","name":"Quantitative Graph Games: Theory and Applications","call_identifier":"FP7"}],"external_id":{"isi":["000650304000002"],"pmid":["33986519"]},"abstract":[{"lang":"eng","text":"Direct and indirect reciprocity are key mechanisms for the evolution of cooperation. Direct reciprocity means that individuals use their own experience to decide whether to cooperate with another person. Indirect reciprocity means that they also consider the experiences of others. Although these two mechanisms are intertwined, they are typically studied in isolation. Here, we introduce a mathematical framework that allows us to explore both kinds of reciprocity simultaneously. We show that the well-known ‘generous tit-for-tat’ strategy of direct reciprocity has a natural analogue in indirect reciprocity, which we call ‘generous scoring’. Using an equilibrium analysis, we characterize under which conditions either of the two strategies can maintain cooperation. With simulations, we additionally explore which kind of reciprocity evolves when members of a population engage in social learning to adapt to their environment. Our results draw unexpected connections between direct and indirect reciprocity while highlighting important differences regarding their evolvability."}],"month":"05","file_date_updated":"2023-11-07T08:27:23Z","type":"journal_article","corr_author":"1","acknowledgement":"This work was supported by the European Research Council CoG 863818 (ForM-SMArt) (to K.C.), the European Research Council Start Grant 279307: Graph Games (to K.C.), and the European Research Council Starting Grant 850529: E-DIRECT (to C.H.). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.","publication_identifier":{"eissn":["2397-3374"]},"isi":1,"_id":"9402","related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/the-emergence-of-cooperation/","description":"News on IST Homepage"}],"record":[{"status":"public","relation":"dissertation_contains","id":"10293"}]},"date_published":"2021-05-13T00:00:00Z","language":[{"iso":"eng"}],"pmid":1,"publication_status":"published","intvolume":"         5"},{"project":[{"_id":"26A151DA-B435-11E9-9278-68D0E5697425","grant_number":"844511","name":"Majorana bound states in Ge/SiGe heterostructures","call_identifier":"H2020"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"},{"call_identifier":"FWF","_id":"2641CE5E-B435-11E9-9278-68D0E5697425","grant_number":"P30207","name":"Hole spin orbit qubits in Ge quantum wells"},{"name":"Hybrid Semiconductor - Superconductor Quantum Devices","_id":"262116AA-B435-11E9-9278-68D0E5697425"}],"external_id":{"pmid":["34083775"],"isi":["000657596400001"],"arxiv":["2011.13755"]},"abstract":[{"lang":"eng","text":"Spin qubits are considered to be among the most promising candidates for building a quantum processor. Group IV hole spin qubits have moved into the focus of interest due to the ease of operation and compatibility with Si technology. In addition, Ge offers the option for monolithic superconductor-semiconductor integration. Here we demonstrate a hole spin qubit operating at fields below 10 mT, the critical field of Al, by exploiting the large out-of-plane hole g-factors in planar Ge and by encoding the qubit into the singlet-triplet states of a double quantum dot. We observe electrically controlled X and Z-rotations with tunable frequencies exceeding 100 MHz and dephasing times of 1μs which we extend beyond 15μs with echo techniques. These results show that Ge hole singlet triplet qubits outperform their electronic Si and GaAs based counterparts in speed and coherence, respectively. In addition, they are on par with Ge single spin qubits, but can be operated at much lower fields underlining their potential for on chip integration with superconducting technologies."}],"type":"journal_article","arxiv":1,"month":"08","corr_author":"1","acknowledgement":"This research was supported by the Scientific Service Units of Institute of Science and Technology (IST) Austria through resources provided by the Miba Machine Shop and the nanofabrication facility, and was made possible with the support of the NOMIS Foundation. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreements no. 844511 and no. 75441, and by the Austrian Science Fund FWF-P 30207 project. A.B. acknowledges support from the European Union Horizon 2020 FET project microSPIRE, no. 766955. M. Botifoll and J.A. acknowledge funding from Generalitat de Catalunya 2017 SGR 327. The Catalan Institute of Nanoscience and Nanotechnology (ICN2) is supported by the Severo Ochoa programme from the Spanish Ministery of Economy (MINECO) (grant no. SEV-2017-0706) and is funded by the Catalonian Research Centre (CERCA) Programme, Generalitat de Catalunya. Part of the present work has been performed within the framework of the Universitat Autónoma de Barcelona Materials Science PhD programme. Part of the HAADF scanning transmission electron microscopy was conducted in the Laboratorio de Microscopias Avanzadas at Instituto de Nanociencia de Aragon, Universidad de Zaragoza. ICN2 acknowledge support from the Spanish Superior Council of Scientific Research (CSIC) Research Platform on Quantum Technologies PTI-001. M.B. acknowledges funding from the Catalan Agency for Management of University and Research Grants (AGAUR) Generalitat de Catalunya formation of investigators (FI) PhD grant.","publication_identifier":{"issn":["1476-1122"],"eissn":["1476-4660"]},"department":[{"_id":"GeKa"},{"_id":"NanoFab"},{"_id":"GradSch"}],"article_processing_charge":"No","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2011.13755"}],"date_created":"2020-12-02T10:50:47Z","oa_version":"Preprint","doi":"10.1038/s41563-021-01022-2","title":"A singlet triplet hole spin qubit in planar Ge","language":[{"iso":"eng"}],"pmid":1,"publication_status":"published","intvolume":"        20","related_material":{"link":[{"description":"News on IST Homepage","relation":"press_release","url":"https://ist.ac.at/en/news/quantum-computing-with-holes/"}],"record":[{"status":"public","relation":"research_data","id":"9323"},{"status":"public","relation":"dissertation_contains","id":"10058"}]},"_id":"8909","isi":1,"date_published":"2021-08-01T00:00:00Z","oa":1,"quality_controlled":"1","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","issue":"8","volume":20,"ec_funded":1,"scopus_import":"1","publisher":"Springer Nature","page":"1106–1112","citation":{"chicago":"Jirovec, Daniel, Andrea C Hofmann, Andrea Ballabio, Philipp M. Mutter, Giulio Tavani, Marc Botifoll, Alessandro Crippa, et al. “A Singlet Triplet Hole Spin Qubit in Planar Ge.” <i>Nature Materials</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41563-021-01022-2\">https://doi.org/10.1038/s41563-021-01022-2</a>.","short":"D. Jirovec, A.C. Hofmann, A. Ballabio, P.M. Mutter, G. Tavani, M. Botifoll, A. Crippa, J. Kukucka, O. Sagi, F. Martins, J. Saez Mollejo, I. Prieto Gonzalez, M. Borovkov, J. Arbiol, D. Chrastina, G. Isella, G. Katsaros, Nature Materials 20 (2021) 1106–1112.","ista":"Jirovec D, Hofmann AC, Ballabio A, Mutter PM, Tavani G, Botifoll M, Crippa A, Kukucka J, Sagi O, Martins F, Saez Mollejo J, Prieto Gonzalez I, Borovkov M, Arbiol J, Chrastina D, Isella G, Katsaros G. 2021. A singlet triplet hole spin qubit in planar Ge. Nature Materials. 20(8), 1106–1112.","ama":"Jirovec D, Hofmann AC, Ballabio A, et al. A singlet triplet hole spin qubit in planar Ge. <i>Nature Materials</i>. 2021;20(8):1106–1112. doi:<a href=\"https://doi.org/10.1038/s41563-021-01022-2\">10.1038/s41563-021-01022-2</a>","mla":"Jirovec, Daniel, et al. “A Singlet Triplet Hole Spin Qubit in Planar Ge.” <i>Nature Materials</i>, vol. 20, no. 8, Springer Nature, 2021, pp. 1106–1112, doi:<a href=\"https://doi.org/10.1038/s41563-021-01022-2\">10.1038/s41563-021-01022-2</a>.","apa":"Jirovec, D., Hofmann, A. C., Ballabio, A., Mutter, P. M., Tavani, G., Botifoll, M., … Katsaros, G. (2021). A singlet triplet hole spin qubit in planar Ge. <i>Nature Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41563-021-01022-2\">https://doi.org/10.1038/s41563-021-01022-2</a>","ieee":"D. Jirovec <i>et al.</i>, “A singlet triplet hole spin qubit in planar Ge,” <i>Nature Materials</i>, vol. 20, no. 8. Springer Nature, pp. 1106–1112, 2021."},"status":"public","publication":"Nature Materials","year":"2021","author":[{"full_name":"Jirovec, Daniel","first_name":"Daniel","last_name":"Jirovec","orcid":"0000-0002-7197-4801","id":"4C473F58-F248-11E8-B48F-1D18A9856A87"},{"id":"340F461A-F248-11E8-B48F-1D18A9856A87","full_name":"Hofmann, Andrea C","last_name":"Hofmann","first_name":"Andrea C"},{"last_name":"Ballabio","first_name":"Andrea","full_name":"Ballabio, Andrea"},{"last_name":"Mutter","first_name":"Philipp M.","full_name":"Mutter, Philipp M."},{"first_name":"Giulio","last_name":"Tavani","full_name":"Tavani, Giulio"},{"last_name":"Botifoll","first_name":"Marc","full_name":"Botifoll, Marc"},{"full_name":"Crippa, Alessandro","last_name":"Crippa","first_name":"Alessandro","id":"1F2B21A2-F6E7-11E9-9B82-F7DBE5697425","orcid":"0000-0002-2968-611X"},{"id":"3F5D8856-F248-11E8-B48F-1D18A9856A87","full_name":"Kukucka, Josip","last_name":"Kukucka","first_name":"Josip"},{"full_name":"Sagi, Oliver","last_name":"Sagi","first_name":"Oliver","id":"71616374-A8E9-11E9-A7CA-09ECE5697425"},{"id":"38F80F9A-1CB8-11EA-BC76-B49B3DDC885E","orcid":"0000-0003-2668-2401","full_name":"Martins, Frederico","first_name":"Frederico","last_name":"Martins"},{"last_name":"Saez Mollejo","first_name":"Jaime","full_name":"Saez Mollejo, Jaime","id":"e0390f72-f6e0-11ea-865d-862393336714"},{"id":"2A307FE2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7370-5357","full_name":"Prieto Gonzalez, Ivan","last_name":"Prieto Gonzalez","first_name":"Ivan"},{"id":"2ac7a0a2-3562-11eb-9256-fbd18ea55087","full_name":"Borovkov, Maksim","last_name":"Borovkov","first_name":"Maksim"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"full_name":"Chrastina, Daniel","last_name":"Chrastina","first_name":"Daniel"},{"last_name":"Isella","first_name":"Giovanni","full_name":"Isella, Giovanni"},{"last_name":"Katsaros","first_name":"Georgios","full_name":"Katsaros, Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8342-202X"}],"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"date_updated":"2026-04-29T22:30:40Z"},{"has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","file":[{"relation":"source_file","file_id":"10186","creator":"cziletti","file_name":"Hana_Semeradova_Disertation_Thesis_II_Revised_3.docx","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":28508629,"checksum":"ce7108853e6cec6224f17cd6429b51fe","date_created":"2021-10-27T07:45:37Z","embargo_to":"open_access","access_level":"closed","date_updated":"2022-12-20T23:30:05Z"},{"date_created":"2021-10-27T07:45:57Z","date_updated":"2022-12-20T23:30:05Z","access_level":"open_access","checksum":"0d7afb846e8e31ec794de47bf44e12ef","file_size":10623525,"content_type":"application/pdf","file_id":"10187","relation":"main_file","embargo":"2022-10-28","file_name":"Hana_Semeradova_Disertation_Thesis_II_Revised_3PDFA.pdf","creator":"cziletti"}],"status":"public","ddc":["570"],"citation":{"mla":"Semerádová, Hana. <i>Molecular Mechanisms of the Cytokinin-Regulated Endomembrane Trafficking to Coordinate Plant Organogenesis</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10135\">10.15479/at:ista:10135</a>.","ieee":"H. Semerádová, “Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis,” Institute of Science and Technology Austria, 2021.","apa":"Semerádová, H. (2021). <i>Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10135\">https://doi.org/10.15479/at:ista:10135</a>","ama":"Semerádová H. Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10135\">10.15479/at:ista:10135</a>","ista":"Semerádová H. 2021. Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis. Institute of Science and Technology Austria.","chicago":"Semerádová, Hana. “Molecular Mechanisms of the Cytokinin-Regulated Endomembrane Trafficking to Coordinate Plant Organogenesis.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10135\">https://doi.org/10.15479/at:ista:10135</a>.","short":"H. Semerádová, Molecular Mechanisms of the Cytokinin-Regulated Endomembrane Trafficking to Coordinate Plant Organogenesis, Institute of Science and Technology Austria, 2021."},"year":"2021","author":[{"id":"42FE702E-F248-11E8-B48F-1D18A9856A87","first_name":"Hana","last_name":"Semerádová","full_name":"Semerádová, Hana"}],"date_updated":"2026-04-08T07:12:06Z","oa":1,"alternative_title":["ISTA Thesis"],"day":"13","OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","supervisor":[{"orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","first_name":"Eva","last_name":"Benková"}],"language":[{"iso":"eng"}],"publication_status":"published","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"9160"}]},"_id":"10135","date_published":"2021-10-13T00:00:00Z","abstract":[{"lang":"eng","text":"Plants maintain the capacity to develop new organs e.g. lateral roots post-embryonically throughout their whole life and thereby flexibly adapt to ever-changing environmental conditions. Plant hormones auxin and cytokinin are the main regulators of the lateral root organogenesis. Additionally to their solo activities, the interaction between auxin and\r\ncytokinin plays crucial role in fine-tuning of lateral root development and growth. In particular, cytokinin modulates auxin distribution within the developing lateral root by affecting the endomembrane trafficking of auxin transporter PIN1 and promoting its vacuolar degradation (Marhavý et al., 2011, 2014). This effect is independent of transcription and\r\ntranslation. Therefore, it suggests novel, non-canonical cytokinin activity occuring possibly on the posttranslational level. Impact of cytokinin and other plant hormones on auxin transporters (including PIN1) on the posttranslational level is described in detail in the introduction part of this thesis in a form of a review (Semeradova et al., 2020). To gain insights into the molecular machinery underlying cytokinin effect on the endomembrane trafficking in the plant cell, in particular on the PIN1 degradation, we conducted two large proteomic screens: 1) Identification of cytokinin binding proteins using\r\nchemical proteomics. 2) Monitoring of proteomic and phosphoproteomic changes upon cytokinin treatment. In the first screen, we identified DYNAMIN RELATED PROTEIN 2A (DRP2A). We found that DRP2A plays a role in cytokinin regulated processes during the plant growth and that cytokinin treatment promotes destabilization of DRP2A protein. However, the role of DRP2A in the PIN1 degradation remains to be elucidated. In the second screen, we found VACUOLAR PROTEIN SORTING 9A (VPS9A). VPS9a plays crucial role in plant’s response to cytokin and in cytokinin mediated PIN1 degradation. Altogether, we identified proteins, which bind to cytokinin and proteins that in response to\r\ncytokinin exhibit significantly changed abundance or phosphorylation pattern. By combining information from these two screens, we can pave our way towards understanding of noncanonical cytokinin effects."}],"file_date_updated":"2022-12-20T23:30:05Z","type":"dissertation","month":"10","project":[{"name":"Molecular mechanisms of the cytokinin regulated endomembrane trafficking to coordinate plant organogenesis","grant_number":"24746","_id":"261821BC-B435-11E9-9278-68D0E5697425"}],"publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-014-5"]},"corr_author":"1","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"degree_awarded":"PhD","title":"Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis","article_processing_charge":"No","oa_version":"Published Version","date_created":"2021-10-13T13:42:48Z","doi":"10.15479/at:ista:10135"},{"ddc":["621","539"],"citation":{"mla":"Jirovec, Daniel. <i>Singlet-Triplet Qubits and Spin-Orbit Interaction in 2-Dimensional Ge Hole Gases</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10058\">10.15479/at:ista:10058</a>.","ieee":"D. Jirovec, “Singlet-Triplet qubits and spin-orbit interaction in 2-dimensional Ge hole gases,” Institute of Science and Technology Austria, 2021.","apa":"Jirovec, D. (2021). <i>Singlet-Triplet qubits and spin-orbit interaction in 2-dimensional Ge hole gases</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10058\">https://doi.org/10.15479/at:ista:10058</a>","ama":"Jirovec D. Singlet-Triplet qubits and spin-orbit interaction in 2-dimensional Ge hole gases. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10058\">10.15479/at:ista:10058</a>","short":"D. Jirovec, Singlet-Triplet Qubits and Spin-Orbit Interaction in 2-Dimensional Ge Hole Gases, Institute of Science and Technology Austria, 2021.","ista":"Jirovec D. 2021. Singlet-Triplet qubits and spin-orbit interaction in 2-dimensional Ge hole gases. Institute of Science and Technology Austria.","chicago":"Jirovec, Daniel. “Singlet-Triplet Qubits and Spin-Orbit Interaction in 2-Dimensional Ge Hole Gases.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10058\">https://doi.org/10.15479/at:ista:10058</a>."},"page":"151","status":"public","file":[{"file_name":"PHD_Thesis_Jirovec_Source.zip","creator":"djirovec","file_id":"10061","relation":"source_file","date_updated":"2022-12-20T23:30:07Z","access_level":"closed","embargo_to":"open_access","date_created":"2021-09-30T14:29:14Z","content_type":"application/x-zip-compressed","file_size":32397600,"checksum":"ad6bcb24083ed7c02baaf1885c9ea3d5"},{"creator":"djirovec","file_name":"PHD_Thesis_pdfa2b_1.pdf","embargo":"2022-10-06","relation":"main_file","file_id":"10087","date_updated":"2022-12-20T23:30:07Z","access_level":"open_access","date_created":"2021-10-05T07:56:49Z","file_size":26910829,"content_type":"application/pdf","checksum":"5fbe08d4f66d1153e04c47971538fae8"}],"publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"date_updated":"2026-04-08T07:12:19Z","author":[{"full_name":"Jirovec, Daniel","last_name":"Jirovec","first_name":"Daniel","orcid":"0000-0002-7197-4801","id":"4C473F58-F248-11E8-B48F-1D18A9856A87"}],"year":"2021","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"supervisor":[{"id":"38DB5788-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8342-202X","first_name":"Georgios","last_name":"Katsaros","full_name":"Katsaros, Georgios"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","day":"05","alternative_title":["ISTA Thesis"],"publication_status":"published","language":[{"iso":"eng"}],"date_published":"2021-10-05T00:00:00Z","keyword":["qubits","quantum computing","holes"],"_id":"10058","related_material":{"record":[{"id":"10066","relation":"part_of_dissertation","status":"public"},{"status":"public","id":"10065","relation":"part_of_dissertation"},{"id":"8831","relation":"part_of_dissertation","status":"public"},{"id":"8909","relation":"part_of_dissertation","status":"public"},{"id":"5816","relation":"part_of_dissertation","status":"public"}]},"acknowledgement":"The author gratefully acknowledges support by the Austrian Science Fund (FWF), grants No P30207, and the Nomis foundation.","corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"project":[{"_id":"2641CE5E-B435-11E9-9278-68D0E5697425","name":"Hole spin orbit qubits in Ge quantum wells","grant_number":"P30207","call_identifier":"FWF"}],"month":"10","type":"dissertation","file_date_updated":"2022-12-20T23:30:07Z","abstract":[{"text":"Quantum information and computation has become a vast field paved with opportunities for researchers and investors. As large multinational companies and international funds are heavily investing in quantum technologies it is still a question which platform is best suited for the task of realizing a scalable quantum processor. In this work we investigate hole spins in Ge quantum wells. These hold great promise as they possess several favorable properties: a small effective mass, a strong spin-orbit coupling, long relaxation time and an inherent immunity to hyperfine noise. All these characteristics helped Ge hole spin qubits to evolve from a single qubit to a fully entangled four qubit processor in only 3 years. Here, we investigated a qubit approach leveraging the large out-of-plane g-factors of heavy hole states in Ge quantum dots. We found this qubit to be reproducibly operable at extremely low magnetic field and at large speeds while maintaining coherence. This was possible because large differences of g-factors in adjacent dots can be achieved in the out-of-plane direction. In the in-plane direction the small g-factors, on the other hand, can be altered very effectively by the confinement potentials. Here, we found that this can even lead to a sign change of the g-factors. The resulting g-factor difference alters the dynamics of the system drastically and produces effects typically attributed to a spin-orbit induced spin-flip term.  The investigations carried out in this thesis give further insights into the possibilities of holes in Ge and reveal new physical properties that need to be considered when designing future spin qubit experiments.","lang":"eng"}],"doi":"10.15479/at:ista:10058","date_created":"2021-09-30T07:53:49Z","oa_version":"Published Version","article_processing_charge":"No","title":"Singlet-Triplet qubits and spin-orbit interaction in 2-dimensional Ge hole gases","degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"GeKa"}]},{"related_material":{"record":[{"id":"9756","relation":"part_of_dissertation","status":"public"},{"id":"9437","relation":"part_of_dissertation","status":"public"},{"id":"612","relation":"part_of_dissertation","status":"public"},{"status":"public","id":"8532","relation":"part_of_dissertation"}]},"_id":"9562","date_published":"2021-06-01T00:00:00Z","language":[{"iso":"eng"}],"publication_status":"published","degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"RySh"}],"date_created":"2021-06-17T14:10:47Z","doi":"10.15479/at:ista:9562","oa_version":"Published Version","article_processing_charge":"No","title":"2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning","file_date_updated":"2022-07-02T22:30:04Z","month":"06","type":"dissertation","abstract":[{"lang":"eng","text":"Left-right asymmetries can be considered a fundamental organizational principle of the vertebrate central nervous system. The hippocampal CA3-CA1 pyramidal cell synaptic connection shows an input-side dependent asymmetry where the hemispheric location of the presynaptic CA3 neuron determines the synaptic properties. Left-input synapses terminating on apical dendrites in stratum radiatum have a higher density of NMDA receptor subunit GluN2B, a lower density of AMPA receptor subunit GluA1 and smaller areas with less often perforated PSDs. On the other hand, left-input synapses terminating on basal dendrites in stratum oriens have lower GluN2B densities than right-input ones. Apical and basal synapses further employ different signaling pathways involved in LTP. SDS-digested freeze-fracture replica labeling can visualize synaptic membrane proteins with high sensitivity and resolution, and has been used to reveal the asymmetry at the electron microscopic level. However, it requires time-consuming manual demarcation of the synaptic surface for quantitative measurements. To facilitate the analysis of replica labeling, I first developed a software named Darea, which utilizes deep-learning to automatize this demarcation. With Darea I characterized the synaptic distribution of NMDA and AMPA receptors as well as the voltage-gated Ca2+ channels in CA1 stratum radiatum and oriens. Second, I explored the role of GluN2B and its carboxy-terminus in the establishment of input-side dependent hippocampal asymmetry. In conditional knock-out mice lacking GluN2B expression in CA1 and GluN2B-2A swap mice, where GluN2B carboxy-terminus was exchanged to that of GluN2A, no significant asymmetries of GluN2B, GluA1 and PSD area were detected. We further discovered a previously unknown functional asymmetry of GluN2A, which was also lost in the swap mouse. These results demonstrate that GluN2B carboxy-terminus plays a critical role in normal formation of input-side dependent asymmetry."}],"corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"author":[{"last_name":"Kleindienst","first_name":"David","full_name":"Kleindienst, David","id":"42E121A4-F248-11E8-B48F-1D18A9856A87"}],"year":"2021","acknowledged_ssus":[{"_id":"EM-Fac"}],"date_updated":"2026-04-08T07:12:31Z","publisher":"Institute of Science and Technology Austria","file":[{"relation":"main_file","embargo":"2022-07-01","file_id":"9563","creator":"dkleindienst","file_name":"Thesis.pdf","content_type":"application/pdf","file_size":77299142,"checksum":"659df5518db495f679cb1df9e9bd1d94","date_created":"2021-06-17T14:03:14Z","access_level":"open_access","date_updated":"2022-07-02T22:30:04Z"},{"file_id":"9564","relation":"source_file","file_name":"Thesis_source.zip","creator":"dkleindienst","file_size":369804895,"checksum":"3bcf63a2b19e5b6663be051bea332748","content_type":"application/zip","date_created":"2021-06-17T14:04:30Z","embargo_to":"open_access","date_updated":"2022-07-02T22:30:04Z","access_level":"closed"}],"has_accepted_license":"1","citation":{"apa":"Kleindienst, D. (2021). <i>2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:9562\">https://doi.org/10.15479/at:ista:9562</a>","mla":"Kleindienst, David. <i>2B or Not 2B: Hippocampal Asymmetries Mediated by NMDA Receptor Subunit GluN2B C-Terminus and High-Throughput Image Analysis by Deep-Learning</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:9562\">10.15479/at:ista:9562</a>.","ama":"Kleindienst D. 2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:9562\">10.15479/at:ista:9562</a>","ieee":"D. Kleindienst, “2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning,” Institute of Science and Technology Austria, 2021.","chicago":"Kleindienst, David. “2B or Not 2B: Hippocampal Asymmetries Mediated by NMDA Receptor Subunit GluN2B C-Terminus and High-Throughput Image Analysis by Deep-Learning.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:9562\">https://doi.org/10.15479/at:ista:9562</a>.","short":"D. Kleindienst, 2B or Not 2B: Hippocampal Asymmetries Mediated by NMDA Receptor Subunit GluN2B C-Terminus and High-Throughput Image Analysis by Deep-Learning, Institute of Science and Technology Austria, 2021.","ista":"Kleindienst D. 2021. 2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning. Institute of Science and Technology Austria."},"page":"124","ddc":["570"],"status":"public","OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","day":"01","alternative_title":["ISTA Thesis"],"supervisor":[{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi"}],"oa":1},{"publication_identifier":{"issn":["2663-337X"]},"corr_author":"1","file_date_updated":"2022-05-21T22:30:04Z","month":"05","type":"dissertation","abstract":[{"text":"Accumulation of interstitial fluid (IF) between embryonic cells is a common phenomenon in vertebrate embryogenesis. Unlike other model systems, where these accumulations coalesce into a large central cavity – the blastocoel, in zebrafish, IF is more uniformly distributed between the deep cells (DC) before the onset of gastrulation. This is likely due to the presence of a large extraembryonic structure – the yolk cell (YC) at the position where the blastocoel typically forms in other model organisms. IF has long been speculated to play a role in tissue morphogenesis during embryogenesis, but direct evidence supporting such function is still sparse. Here we show that the relocalization of IF to the interface between the YC and DC/epiblast is critical for axial mesendoderm (ME) cell protrusion formation and migration along this interface, a key process in embryonic axis formation. We further demonstrate that axial ME cell migration and IF relocalization engage in a positive feedback loop, where axial ME migration triggers IF accumulation ahead of the advancing axial ME tissue by mechanically compressing the overlying epiblast cell layer. Upon compression, locally induced flow relocalizes the IF through the porous epiblast tissue resulting in an IF accumulation ahead of the leading axial ME. This IF accumulation, in turn, promotes cell protrusion formation and migration of the leading axial ME cells, thereby facilitating axial ME extension. Our findings reveal a central role of dynamic IF relocalization in orchestrating germ layer morphogenesis during gastrulation.","lang":"eng"}],"title":"Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation","doi":"10.15479/at:ista:9397","date_created":"2021-05-17T12:31:30Z","oa_version":"Published Version","article_processing_charge":"No","degree_awarded":"PhD","department":[{"_id":"CaHe"},{"_id":"GradSch"}],"publication_status":"published","language":[{"iso":"eng"}],"date_published":"2021-05-18T00:00:00Z","_id":"9397","oa":1,"supervisor":[{"last_name":"Heisenberg","first_name":"Carl-Philipp J","full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87"}],"day":"18","alternative_title":["ISTA Thesis"],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","status":"public","ddc":["571"],"page":"101","citation":{"ista":"Huljev K. 2021. Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation. Institute of Science and Technology Austria.","chicago":"Huljev, Karla. “Coordinated Spatiotemporal Reorganization of Interstitial Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:9397\">https://doi.org/10.15479/at:ista:9397</a>.","short":"K. Huljev, Coordinated Spatiotemporal Reorganization of Interstitial Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation, Institute of Science and Technology Austria, 2021.","ama":"Huljev K. Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:9397\">10.15479/at:ista:9397</a>","mla":"Huljev, Karla. <i>Coordinated Spatiotemporal Reorganization of Interstitial Fluid Is Required for Axial Mesendoderm Migration in Zebrafish Gastrulation</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:9397\">10.15479/at:ista:9397</a>.","ieee":"K. Huljev, “Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation,” Institute of Science and Technology Austria, 2021.","apa":"Huljev, K. (2021). <i>Coordinated spatiotemporal reorganization of interstitial fluid is required for axial mesendoderm migration in zebrafish gastrulation</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:9397\">https://doi.org/10.15479/at:ista:9397</a>"},"file":[{"date_created":"2021-05-17T12:29:12Z","embargo_to":"open_access","access_level":"closed","date_updated":"2022-05-21T22:30:04Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":47799741,"checksum":"7f98532f5324a0b2f3fa8de2967baa19","relation":"source_file","file_id":"9398","creator":"khuljev","file_name":"KHuljev_Thesis_corrections.docx"},{"checksum":"bf512f8a1e572a543778fc4b227c01ba","content_type":"application/pdf","file_size":16542131,"date_created":"2021-05-18T14:50:28Z","access_level":"open_access","date_updated":"2022-05-21T22:30:04Z","file_id":"9401","embargo":"2022-05-20","relation":"main_file","file_name":"new_KHuljev_Thesis_corrections.pdf","creator":"khuljev"}],"publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","date_updated":"2026-04-08T07:12:51Z","author":[{"full_name":"Huljev, Karla","last_name":"Huljev","first_name":"Karla","id":"44C6F6A6-F248-11E8-B48F-1D18A9856A87"}],"year":"2021"},{"has_accepted_license":"1","file":[{"file_name":"ThesisTomasekKathrin.pdf","creator":"ktomasek","file_id":"10308","relation":"main_file","embargo":"2022-11-18","access_level":"open_access","date_updated":"2022-12-20T23:30:05Z","date_created":"2021-11-18T15:07:31Z","file_size":13266088,"checksum":"b39c9e0ef18d0484d537a67551effd02","content_type":"application/pdf"},{"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":7539509,"checksum":"c0c440ee9e5ef1102a518a4f9f023e7c","date_updated":"2022-12-20T23:30:05Z","access_level":"closed","embargo_to":"open_access","date_created":"2021-11-18T15:07:46Z","creator":"ktomasek","file_name":"ThesisTomasekKathrin.docx","relation":"source_file","file_id":"10309"}],"publisher":"Institute of Science and Technology Austria","page":"73","citation":{"ista":"Tomasek K. 2021. Pathogenic Escherichia coli hijack the host immune response. Institute of Science and Technology Austria.","chicago":"Tomasek, Kathrin. “Pathogenic Escherichia Coli Hijack the Host Immune Response.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10307\">https://doi.org/10.15479/at:ista:10307</a>.","short":"K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.","ama":"Tomasek K. Pathogenic Escherichia coli hijack the host immune response. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10307\">10.15479/at:ista:10307</a>","apa":"Tomasek, K. (2021). <i>Pathogenic Escherichia coli hijack the host immune response</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10307\">https://doi.org/10.15479/at:ista:10307</a>","mla":"Tomasek, Kathrin. <i>Pathogenic Escherichia Coli Hijack the Host Immune Response</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10307\">10.15479/at:ista:10307</a>.","ieee":"K. Tomasek, “Pathogenic Escherichia coli hijack the host immune response,” Institute of Science and Technology Austria, 2021."},"ddc":["570"],"status":"public","year":"2021","author":[{"id":"3AEC8556-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3768-877X","full_name":"Tomasek, Kathrin","first_name":"Kathrin","last_name":"Tomasek"}],"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"},{"_id":"PreCl"},{"_id":"EM-Fac"}],"date_updated":"2026-04-08T07:14:01Z","oa":1,"OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","alternative_title":["ISTA Thesis"],"day":"18","supervisor":[{"id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","full_name":"Sixt, Michael K","first_name":"Michael K","last_name":"Sixt"},{"last_name":"Guet","first_name":"Calin C","full_name":"Guet, Calin C","orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"publication_status":"published","_id":"10307","related_material":{"record":[{"status":"public","id":"10316","relation":"part_of_dissertation"}]},"date_published":"2021-11-18T00:00:00Z","abstract":[{"text":"Bacteria-host interactions represent a continuous trade-off between benefit and risk. Thus, the host immune response is faced with a non-trivial problem – accommodate beneficial commensals and remove harmful pathogens. This is especially difficult as molecular patterns, such as lipopolysaccharide or specific surface organelles such as pili, are conserved in both, commensal and pathogenic bacteria. Type 1 pili, tightly regulated by phase variation, are considered an important virulence factor of pathogenic bacteria as they facilitate invasion into host cells. While invasion represents a de facto passive mechanism for pathogens to escape the host immune response, we demonstrate a fundamental role of type 1 pili as active modulators of the innate and adaptive immune response.","lang":"eng"}],"type":"dissertation","file_date_updated":"2022-12-20T23:30:05Z","month":"11","corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"department":[{"_id":"MiSi"},{"_id":"CaGu"},{"_id":"GradSch"}],"degree_awarded":"PhD","article_processing_charge":"No","doi":"10.15479/at:ista:10307","date_created":"2021-11-18T15:05:06Z","oa_version":"Published Version","title":"Pathogenic Escherichia coli hijack the host immune response"},{"publication_status":"published","language":[{"iso":"eng"}],"date_published":"2021-09-02T00:00:00Z","related_material":{"record":[{"status":"public","id":"8569","relation":"part_of_dissertation"},{"status":"public","id":"960","relation":"part_of_dissertation"}]},"_id":"9962","keyword":["Neuronal migration","Non-cell-autonomous","Cell-autonomous","Neurodevelopmental disease"],"publication_identifier":{"issn":["2663-337X"]},"corr_author":"1","month":"09","file_date_updated":"2022-09-03T22:30:04Z","type":"dissertation","abstract":[{"lang":"eng","text":"The brain is one of the largest and most complex organs and it is composed of billions of neurons that communicate together enabling e.g. consciousness. The cerebral cortex is the largest site of neural integration in the central nervous system. Concerted radial migration of newly born cortical projection neurons, from their birthplace to their final position, is a key step in the assembly of the cerebral cortex. The cellular and molecular mechanisms regulating radial neuronal migration in vivo are however still unclear. Recent evidence suggests that distinct signaling cues act cell-autonomously but differentially at certain steps during the overall migration process. Moreover, functional analysis of genetic mosaics (mutant neurons present in wild-type/heterozygote environment) using the MADM (Mosaic Analysis with Double Markers) analyses in comparison to global knockout also indicate a significant degree of non-cell-autonomous and/or community effects in the control of cortical neuron migration. The interactions of cell-intrinsic (cell-autonomous) and cell-extrinsic (non-cell-autonomous) components are largely unknown. In part of this thesis work we established a MADM-based experimental strategy for the quantitative analysis of cell-autonomous gene function versus non-cell-autonomous and/or community effects. The direct comparison of mutant neurons from the genetic mosaic (cell-autonomous) to mutant neurons in the conditional and/or global knockout (cell-autonomous + non-cell-autonomous) allows to quantitatively analyze non-cell-autonomous effects. Such analysis enable the high-resolution analysis of projection neuron migration dynamics in distinct environments with concomitant isolation of genomic and proteomic profiles. Using these experimental paradigms and in combination with computational modeling we show and characterize the nature of non-cell-autonomous effects to coordinate radial neuron migration. Furthermore, this thesis discusses recent developments in neurodevelopment with focus on neuronal polarization and non-cell-autonomous mechanisms in neuronal migration."}],"project":[{"name":"Molecular mechanisms of radial neuronal migration","grant_number":"24812","_id":"2625A13E-B435-11E9-9278-68D0E5697425"}],"title":"Cell-autonomous gene function and non-cell-autonomous effects in radial projection neuron migration","doi":"10.15479/at:ista:9962","date_created":"2021-08-29T12:36:50Z","oa_version":"Published Version","article_processing_charge":"No","degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"SiHi"}],"status":"public","page":"182","citation":{"mla":"Hansen, Andi H. <i>Cell-Autonomous Gene Function and Non-Cell-Autonomous Effects in Radial Projection Neuron Migration</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:9962\">10.15479/at:ista:9962</a>.","apa":"Hansen, A. H. (2021). <i>Cell-autonomous gene function and non-cell-autonomous effects in radial projection neuron migration</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:9962\">https://doi.org/10.15479/at:ista:9962</a>","ama":"Hansen AH. Cell-autonomous gene function and non-cell-autonomous effects in radial projection neuron migration. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:9962\">10.15479/at:ista:9962</a>","ieee":"A. H. Hansen, “Cell-autonomous gene function and non-cell-autonomous effects in radial projection neuron migration,” Institute of Science and Technology Austria, 2021.","short":"A.H. Hansen, Cell-Autonomous Gene Function and Non-Cell-Autonomous Effects in Radial Projection Neuron Migration, Institute of Science and Technology Austria, 2021.","chicago":"Hansen, Andi H. “Cell-Autonomous Gene Function and Non-Cell-Autonomous Effects in Radial Projection Neuron Migration.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:9962\">https://doi.org/10.15479/at:ista:9962</a>.","ista":"Hansen AH. 2021. Cell-autonomous gene function and non-cell-autonomous effects in radial projection neuron migration. Institute of Science and Technology Austria."},"ddc":["570"],"file":[{"embargo_to":"open_access","date_created":"2021-08-30T09:17:39Z","access_level":"closed","date_updated":"2022-09-03T22:30:04Z","checksum":"66b56f5b988b233dc66a4f4b4fb2cdfe","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":10629190,"relation":"source_file","file_id":"9971","creator":"ahansen","file_name":"Thesis_Hansen.docx"},{"file_name":"Thesis_Hansen_PDFA-1a.pdf","creator":"ahansen","file_id":"9972","embargo":"2022-09-02","relation":"main_file","access_level":"open_access","date_updated":"2022-09-03T22:30:04Z","date_created":"2021-08-30T09:29:44Z","file_size":13457469,"checksum":"204fa40321a1c6289b68c473634c4bf3","content_type":"application/pdf"}],"publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","date_updated":"2026-04-08T07:19:09Z","author":[{"id":"38853E16-F248-11E8-B48F-1D18A9856A87","first_name":"Andi H","last_name":"Hansen","full_name":"Hansen, Andi H"}],"year":"2021","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"supervisor":[{"last_name":"Hippenmeyer","first_name":"Simon","full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061"}],"day":"02","alternative_title":["ISTA Thesis"],"OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd"},{"has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","file":[{"creator":"scaballe","file_name":"PhDThesis_SCM.docx","relation":"source_file","file_id":"9624","access_level":"closed","date_updated":"2022-07-02T22:30:06Z","embargo_to":"open_access","date_created":"2021-07-01T14:48:54Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":131946790,"checksum":"e039225a47ef32666d59bf35ddd30ecf"},{"checksum":"dd4d78962ea94ad95e97ca7d9af08f4b","content_type":"application/pdf","file_size":17094958,"access_level":"open_access","date_updated":"2022-07-02T22:30:06Z","date_created":"2021-07-01T14:46:25Z","creator":"scaballe","file_name":"PhDThesis_SCM.pdf","relation":"main_file","embargo":"2022-07-01","file_id":"9625"}],"status":"public","ddc":["570"],"page":"111","citation":{"chicago":"Caballero Mancebo, Silvia. “Fertilization-Induced Deformations Are Controlled by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:9623\">https://doi.org/10.15479/at:ista:9623</a>.","short":"S. Caballero Mancebo, Fertilization-Induced Deformations Are Controlled by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes, Institute of Science and Technology Austria, 2021.","ista":"Caballero Mancebo S. 2021. Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes. Institute of Science and Technology Austria.","mla":"Caballero Mancebo, Silvia. <i>Fertilization-Induced Deformations Are Controlled by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:9623\">10.15479/at:ista:9623</a>.","apa":"Caballero Mancebo, S. (2021). <i>Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:9623\">https://doi.org/10.15479/at:ista:9623</a>","ieee":"S. Caballero Mancebo, “Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes,” Institute of Science and Technology Austria, 2021.","ama":"Caballero Mancebo S. Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:9623\">10.15479/at:ista:9623</a>"},"year":"2021","author":[{"orcid":"0000-0002-5223-3346","id":"2F1E1758-F248-11E8-B48F-1D18A9856A87","first_name":"Silvia","last_name":"Caballero Mancebo","full_name":"Caballero Mancebo, Silvia"}],"date_updated":"2026-04-08T07:19:38Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"NanoFab"},{"_id":"M-Shop"}],"oa":1,"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"alternative_title":["ISTA Thesis"],"OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","supervisor":[{"last_name":"Heisenberg","first_name":"Carl-Philipp J","full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"publication_status":"published","related_material":{"record":[{"id":"9750","relation":"part_of_dissertation","status":"public"},{"relation":"part_of_dissertation","id":"9006","status":"public"}]},"_id":"9623","date_published":"2021-07-01T00:00:00Z","abstract":[{"lang":"eng","text":"Cytoplasmic reorganizations are essential for morphogenesis. In large cells like oocytes, these reorganizations become crucial in patterning the oocyte for later stages of embryonic development. Ascidians oocytes reorganize their cytoplasm (ooplasm) in a spectacular manner. Ooplasmic reorganization is initiated at fertilization with the contraction of the actomyosin cortex along the animal-vegetal axis of the oocyte, driving the accumulation of cortical endoplasmic reticulum (cER), maternal mRNAs associated to it and a mitochondria-rich subcortical layer – the myoplasm – in a region of the vegetal pole termed contraction pole (CP). Here we have used the species Phallusia mammillata to investigate the changes in cell shape that accompany these reorganizations and the mechanochemical mechanisms underlining CP formation.\r\nWe report that the length of the animal-vegetal (AV) axis oscillates upon fertilization: it first undergoes a cycle of fast elongation-lengthening followed by a slow expansion of mainly the vegetal pole (VP) of the cell. We show that the fast oscillation corresponds to a dynamic polarization of the actin cortex as a result of a fertilization-induced increase in cortical tension in the oocyte that triggers a rupture of the cortex at the animal pole and the establishment of vegetal-directed cortical flows. These flows are responsible for the vegetal accumulation of actin causing the VP to flatten. \r\nWe find that the slow expansion of the VP, leading to CP formation, correlates with a relaxation of the vegetal cortex and that the myoplasm plays a role in the expansion. We show that the myoplasm is a solid-like layer that buckles under compression forces arising from the contracting actin cortex at the VP. Straightening of the myoplasm when actin flows stops, facilitates the expansion of the VP and the CP. Altogether, our results present a previously unrecognized role for the myoplasm in ascidian ooplasmic segregation. \r\n"}],"month":"07","file_date_updated":"2022-07-02T22:30:06Z","type":"dissertation","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-012-1"]},"corr_author":"1","department":[{"_id":"GradSch"},{"_id":"CaHe"}],"degree_awarded":"PhD","title":"Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes","article_processing_charge":"No","doi":"10.15479/at:ista:9623","oa_version":"Published Version","date_created":"2021-07-01T14:50:17Z"},{"scopus_import":"1","has_accepted_license":"1","publisher":"Wiley","file":[{"content_type":"application/pdf","file_size":3144854,"checksum":"750de03dc3b715c37090126c1548ba13","date_created":"2021-10-05T13:36:42Z","success":1,"date_updated":"2021-10-05T13:36:42Z","access_level":"open_access","file_id":"10090","relation":"main_file","file_name":"2021_EmboR_Vega.pdf","creator":"cchlebak"}],"status":"public","publication":"EMBO Reports","citation":{"mla":"Vega, Andrea, et al. “Nitrate Triggered Phosphoproteome Changes and a PIN2 Phosphosite Modulating Root System Architecture.” <i>EMBO Reports</i>, vol. 22, no. 9, e51813, Wiley, 2021, doi:<a href=\"https://doi.org/10.15252/embr.202051813\">10.15252/embr.202051813</a>.","ama":"Vega A, Fredes I, O’Brien J, et al. Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture. <i>EMBO Reports</i>. 2021;22(9). doi:<a href=\"https://doi.org/10.15252/embr.202051813\">10.15252/embr.202051813</a>","apa":"Vega, A., Fredes, I., O’Brien, J., Shen, Z., Ötvös, K., Abualia, R., … Gutiérrez, R. A. (2021). Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture. <i>EMBO Reports</i>. Wiley. <a href=\"https://doi.org/10.15252/embr.202051813\">https://doi.org/10.15252/embr.202051813</a>","ieee":"A. Vega <i>et al.</i>, “Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture,” <i>EMBO Reports</i>, vol. 22, no. 9. Wiley, 2021.","chicago":"Vega, Andrea, Isabel Fredes, José O’Brien, Zhouxin Shen, Krisztina Ötvös, Rashed Abualia, Eva Benková, Steven P. Briggs, and Rodrigo A. Gutiérrez. “Nitrate Triggered Phosphoproteome Changes and a PIN2 Phosphosite Modulating Root System Architecture.” <i>EMBO Reports</i>. Wiley, 2021. <a href=\"https://doi.org/10.15252/embr.202051813\">https://doi.org/10.15252/embr.202051813</a>.","short":"A. Vega, I. Fredes, J. O’Brien, Z. Shen, K. Ötvös, R. Abualia, E. Benková, S.P. Briggs, R.A. Gutiérrez, EMBO Reports 22 (2021).","ista":"Vega A, Fredes I, O’Brien J, Shen Z, Ötvös K, Abualia R, Benková E, Briggs SP, Gutiérrez RA. 2021. Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture. EMBO Reports. 22(9), e51813."},"article_number":"e51813","ddc":["580"],"year":"2021","author":[{"first_name":"Andrea","last_name":"Vega","full_name":"Vega, Andrea"},{"last_name":"Fredes","first_name":"Isabel","full_name":"Fredes, Isabel"},{"full_name":"O’Brien, José","last_name":"O’Brien","first_name":"José"},{"full_name":"Shen, Zhouxin","first_name":"Zhouxin","last_name":"Shen"},{"id":"29B901B0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5503-4983","first_name":"Krisztina","last_name":"Ötvös","full_name":"Ötvös, Krisztina"},{"id":"4827E134-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9357-9415","first_name":"Rashed","last_name":"Abualia","full_name":"Abualia, Rashed"},{"full_name":"Benková, Eva","last_name":"Benková","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739"},{"first_name":"Steven P.","last_name":"Briggs","full_name":"Briggs, Steven P."},{"full_name":"Gutiérrez, Rodrigo A.","first_name":"Rodrigo A.","last_name":"Gutiérrez"}],"date_updated":"2026-04-29T22:30:45Z","quality_controlled":"1","article_type":"original","oa":1,"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"day":"06","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":22,"issue":"9","language":[{"iso":"eng"}],"publication_status":"published","intvolume":"        22","pmid":1,"isi":1,"_id":"9913","related_material":{"record":[{"relation":"dissertation_contains","id":"10303","status":"public"}]},"date_published":"2021-09-06T00:00:00Z","abstract":[{"text":"Nitrate commands genome-wide gene expression changes that impact metabolism, physiology, plant growth, and development. In an effort to identify new components involved in nitrate responses in plants, we analyze the Arabidopsis thaliana root phosphoproteome in response to nitrate treatments via liquid chromatography coupled to tandem mass spectrometry. 176 phosphoproteins show significant changes at 5 or 20 min after nitrate treatments. Proteins identified by 5 min include signaling components such as kinases or transcription factors. In contrast, by 20 min, proteins identified were associated with transporter activity or hormone metabolism functions, among others. The phosphorylation profile of NITRATE TRANSPORTER 1.1 (NRT1.1) mutant plants was significantly altered as compared to wild-type plants, confirming its key role in nitrate signaling pathways that involves phosphorylation changes. Integrative bioinformatics analysis highlights auxin transport as an important mechanism modulated by nitrate signaling at the post-translational level. We validated a new phosphorylation site in PIN2 and provide evidence that it functions in primary and lateral root growth responses to nitrate.","lang":"eng"}],"file_date_updated":"2021-10-05T13:36:42Z","month":"09","type":"journal_article","external_id":{"pmid":["34357701 "],"isi":["000681754200001"]},"publication_identifier":{"eissn":["1469-3178"],"issn":["1469-221X"]},"acknowledgement":"This work was supported by ANID—Millennium Science Initiative Program—ICN17_022, Fondo de Desarrollo de Areas Prioritarias (FONDAP) Center for Genome Regulation (15090007), ANID—Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) 1180759 (to RAG) and 1171631 (to AV). We would like to thank Unidad de Microscopía Avanzada UC (UMA UC).","department":[{"_id":"EvBe"},{"_id":"GradSch"}],"title":"Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture","article_processing_charge":"Yes","date_created":"2021-08-15T22:01:30Z","doi":"10.15252/embr.202051813","oa_version":"Published Version"},{"language":[{"iso":"eng"}],"publication_status":"published","related_material":{"record":[{"id":"47","relation":"part_of_dissertation","status":"public"},{"relation":"part_of_dissertation","id":"9913","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"9010"}]},"_id":"10303","date_published":"2021-11-22T00:00:00Z","abstract":[{"lang":"eng","text":"Nitrogen is an essential macronutrient determining plant growth, development and affecting agricultural productivity. Root, as a hub that perceives and integrates local and systemic signals on the plant’s external and endogenous nitrogen resources, communicates with other plant organs to consolidate their physiology and development in accordance with actual nitrogen balance. Over the last years, numerous studies demonstrated that these comprehensive developmental adaptations rely on the interaction between pathways controlling nitrogen homeostasis and hormonal networks acting globally in the plant body. However, molecular insights into how the information about the nitrogen status is translated through hormonal pathways into specific developmental output are lacking. In my work, I addressed so far poorly understood mechanisms underlying root-to-shoot communication that lead to a rapid re-adjustment of shoot growth and development after nitrate provision. Applying a combination of molecular, cell, and developmental biology approaches, genetics and grafting experiments as well as hormonal analytics, I identified and characterized an unknown molecular framework orchestrating shoot development with a root nitrate sensory system. "}],"type":"dissertation","month":"11","file_date_updated":"2022-12-20T23:30:06Z","corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"degree_awarded":"PhD","article_processing_charge":"No","oa_version":"Published Version","date_created":"2021-11-18T11:20:59Z","doi":"10.15479/at:ista:10303","title":"Role of hormones in nitrate regulated growth","has_accepted_license":"1","file":[{"file_id":"10331","relation":"main_file","embargo":"2022-11-23","file_name":"AbualiaPhDthesisfinalv3.pdf","creator":"rabualia","content_type":"application/pdf","file_size":28005730,"checksum":"dea38b98aa4da1cea03dcd0f10862818","date_created":"2021-11-22T14:48:21Z","date_updated":"2022-12-20T23:30:06Z","access_level":"open_access"},{"date_updated":"2022-12-20T23:30:06Z","access_level":"closed","embargo_to":"open_access","date_created":"2021-11-22T14:48:34Z","checksum":"4cd62da5ec5ba4c32e61f0f6d9e61920","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_size":62841883,"creator":"rabualia","file_name":"AbualiaPhDthesisfinalv3.docx","relation":"source_file","file_id":"10332"}],"publisher":"Institute of Science and Technology Austria","citation":{"mla":"Abualia, Rashed. <i>Role of Hormones in Nitrate Regulated Growth</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10303\">10.15479/at:ista:10303</a>.","apa":"Abualia, R. (2021). <i>Role of hormones in nitrate regulated growth</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10303\">https://doi.org/10.15479/at:ista:10303</a>","ama":"Abualia R. Role of hormones in nitrate regulated growth. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10303\">10.15479/at:ista:10303</a>","ieee":"R. Abualia, “Role of hormones in nitrate regulated growth,” Institute of Science and Technology Austria, 2021.","chicago":"Abualia, Rashed. “Role of Hormones in Nitrate Regulated Growth.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10303\">https://doi.org/10.15479/at:ista:10303</a>.","ista":"Abualia R. 2021. Role of hormones in nitrate regulated growth. Institute of Science and Technology Austria.","short":"R. Abualia, Role of Hormones in Nitrate Regulated Growth, Institute of Science and Technology Austria, 2021."},"page":"139","ddc":["580","581"],"status":"public","year":"2021","author":[{"orcid":"0000-0002-9357-9415","id":"4827E134-F248-11E8-B48F-1D18A9856A87","first_name":"Rashed","last_name":"Abualia","full_name":"Abualia, Rashed"}],"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"date_updated":"2026-04-08T07:20:07Z","oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","alternative_title":["ISTA Thesis"],"day":"22","supervisor":[{"first_name":"Eva","last_name":"Benková","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"}]}]