---
OA_place: publisher
_id: '21957'
abstract:
- lang: eng
  text: "This thesis investigates algorithmic certification and approximation methods
    for degenerate semidefinite programs (SDPs) and the singular roots of polynomial
    systems. In the first part, we present a hybrid symbolic-numeric algorithm for
    certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating
    linear matrix inequalities (LMIs) into a structured polynomial system via facial
    reduction and incidence varieties, we guarantee the existence of an isolated exact
    solution. This algebraic reduction enables the certification of maximum-rank numerical
    approximations using methods from algebraic geometry.\r\n\r\nIn the second part,
    we address the severe ill-conditioning and loss of quadratic convergence that
    plague standard path-tracking methods near isolated singular roots. To overcome
    this, we propose tracking algorithms that achieve superlinear convergence without
    the computational bloat characteristic of classical deflation techniques. By modeling
    the solution path as a generalized fractional Puiseux series, our approach combines
    an explicitly derived algebraic predictor with a localized hyperplane desingularization
    phase during the corrector step. Furthermore, we introduce a continuous path-limit
    method and an extension of the geometric sequence rule to directly extract exact
    fractional exponents. This bypasses traditional heuristic trial-and-error methods
    and explicitly accommodates sparse series expansions. Numerical experiments confirm
    that our method significantly reduces the cumulative number of matrix inversions
    while achieving high-accuracy root approximations, even for heavily degenerate
    systems exhibiting higher coranks."
acknowledgement: 'Funding: Vienna Graduate School on Computational Optimization (FWF),
  grant DOI: 10.55776/W1260.'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jeferson
  full_name: Zapata, Jeferson
  id: 00223538-AF8F-11E9-A4C7-F729E6697425
  last_name: Zapata
citation:
  ama: 'Zapata J. Overcoming degeneracy and singularity: Techniques for semidefinite
    programs and homotopy continuation endgames. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-21957">10.15479/AT-ISTA-21957</a>'
  apa: 'Zapata, J. (2026). <i>Overcoming degeneracy and singularity: Techniques for
    semidefinite programs and homotopy continuation endgames</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21957">https://doi.org/10.15479/AT-ISTA-21957</a>'
  chicago: 'Zapata, Jeferson. “Overcoming Degeneracy and Singularity: Techniques for
    Semidefinite Programs and Homotopy Continuation Endgames.” Institute of Science
    and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21957">https://doi.org/10.15479/AT-ISTA-21957</a>.'
  ieee: 'J. Zapata, “Overcoming degeneracy and singularity: Techniques for semidefinite
    programs and homotopy continuation endgames,” Institute of Science and Technology
    Austria, 2026.'
  ista: 'Zapata J. 2026. Overcoming degeneracy and singularity: Techniques for semidefinite
    programs and homotopy continuation endgames. Institute of Science and Technology
    Austria.'
  mla: 'Zapata, Jeferson. <i>Overcoming Degeneracy and Singularity: Techniques for
    Semidefinite Programs and Homotopy Continuation Endgames</i>. Institute of Science
    and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21957">10.15479/AT-ISTA-21957</a>.'
  short: 'J. Zapata, Overcoming Degeneracy and Singularity: Techniques for Semidefinite
    Programs and Homotopy Continuation Endgames, Institute of Science and Technology
    Austria, 2026.'
corr_author: '1'
das_tickbox: '1'
date_created: 2026-06-08T13:29:52Z
date_published: 2026-06-09T00:00:00Z
date_updated: 2026-07-27T14:30:42Z
day: '09'
ddc:
- '500'
degree_awarded: PhD
department:
- _id: GradSch
- _id: VlKo
doi: 10.15479/AT-ISTA-21957
doi_confirm: '1'
file:
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  content_type: application/zip
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  file_size: 40811933
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  date_updated: 2026-06-10T13:33:25Z
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  file_name: 4_Final_Thesis_JZapata_REX.pdf
  file_size: 2207892
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file_date_updated: 2026-06-10T13:33:25Z
fulldoi: https://doi.org/10.15479/AT-ISTA-21957
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '06'
oa: 1
oa_version: Published Version
page: '89'
project:
- _id: 9B9290DE-BA93-11EA-9121-9846C619BF3A
  grant_number: W1260-N35
  name: Vienna Graduate School on Computational Optimization
publication_identifier:
  isbn:
  - 978-3-99078-079-4
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '21144'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
title: 'Overcoming degeneracy and singularity: Techniques for semidefinite programs
  and homotopy continuation endgames'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: repository
_id: '21360'
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: "I would like to acknowledge the Austrian Academy of Sciences (ÖAW)
  and European\r\nResearch Executive Agency (REA) for funding my research (DOC ÖAW
  Fellowship\r\n26130, Horizon Europe BOLERO Project 101060393). "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Stefan
  full_name: Riegler, Stefan
  id: FF6018E0-D806-11E9-8E43-0B14E6697425
  last_name: Riegler
  orcid: 0000-0003-3413-1343
citation:
  ama: 'Riegler S. Root system plasticity under nutrient limitation: Investigating
    hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. 2026.
    doi:<a href="https://doi.org/10.15479/AT-ISTA-21360">10.15479/AT-ISTA-21360</a>'
  apa: 'Riegler, S. (2026). <i>Root system plasticity under nutrient limitation: Investigating
    hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21360">https://doi.org/10.15479/AT-ISTA-21360</a>'
  chicago: 'Riegler, Stefan. “Root System Plasticity under Nutrient Limitation: Investigating
    Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species.” Institute
    of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21360">https://doi.org/10.15479/AT-ISTA-21360</a>.'
  ieee: 'S. Riegler, “Root system plasticity under nutrient limitation: Investigating
    hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species,” Institute
    of Science and Technology Austria, 2026.'
  ista: 'Riegler S. 2026. Root system plasticity under nutrient limitation: Investigating
    hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. Institute
    of Science and Technology Austria.'
  mla: 'Riegler, Stefan. <i>Root System Plasticity under Nutrient Limitation: Investigating
    Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species</i>.
    Institute of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21360">10.15479/AT-ISTA-21360</a>.'
  short: 'S. Riegler, Root System Plasticity under Nutrient Limitation: Investigating
    Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species, Institute
    of Science and Technology Austria, 2026.'
corr_author: '1'
das_tickbox: '1'
date_created: 2026-02-27T09:08:14Z
date_published: 2026-02-26T00:00:00Z
date_updated: 2026-07-27T14:30:08Z
day: '26'
ddc:
- '570'
- '575'
- '583'
degree_awarded: PhD
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/AT-ISTA-21360
doi_confirm: '1'
file:
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  date_updated: 2026-03-02T10:59:49Z
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has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-sa/4.0/
month: '02'
oa_version: Published Version
page: '185'
project:
- _id: 34afa094-11ca-11ed-8bc3-a375845a59fb
  grant_number: '101060393'
  name: Breeding for coffee and cocoa root resilience in low input farming systems
    based on improved rootstocks
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '21363'
    relation: research_data
    status: public
status: public
supervisor:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
title: 'Root system plasticity under nutrient limitation: Investigating hormonal and
  molecular drivers in Arabidopsis thaliana and Coffea  species'
tmp:
  image: /images/cc_by_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
  name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
_id: '21363'
abstract:
- lang: eng
  text: The data contains information on coffee differential gene expression as well
    as co-expression and trait correlations in two separate experiments. First, contrasting
    nitrogen supply, second, intra- and interspecific grafting.
article_processing_charge: No
author:
- first_name: Stefan
  full_name: Riegler, Stefan
  id: FF6018E0-D806-11E9-8E43-0B14E6697425
  last_name: Riegler
  orcid: 0000-0003-3413-1343
citation:
  ama: 'Riegler S. Thesis Data for Root System Plasticity under Nutrient Limitation:
    Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea 
    species. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-21363">10.15479/AT-ISTA-21363</a>'
  apa: 'Riegler, S. (2026). Thesis Data for Root System Plasticity under Nutrient
    Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana
    and Coffea  species. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21363">https://doi.org/10.15479/AT-ISTA-21363</a>'
  chicago: 'Riegler, Stefan. “Thesis Data for Root System Plasticity under Nutrient
    Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana
    and Coffea  Species.” Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21363">https://doi.org/10.15479/AT-ISTA-21363</a>.'
  ieee: 'S. Riegler, “Thesis Data for Root System Plasticity under Nutrient Limitation:
    Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea 
    species.” Institute of Science and Technology Austria, 2026.'
  ista: 'Riegler S. 2026. Thesis Data for Root System Plasticity under Nutrient Limitation:
    Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea 
    species, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT-ISTA-21363">10.15479/AT-ISTA-21363</a>.'
  mla: 'Riegler, Stefan. <i>Thesis Data for Root System Plasticity under Nutrient
    Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana
    and Coffea  Species</i>. Institute of Science and Technology Austria, 2026, doi:<a
    href="https://doi.org/10.15479/AT-ISTA-21363">10.15479/AT-ISTA-21363</a>.'
  short: S. Riegler, (2026).
contributor:
- contributor_type: supervisor
  first_name: Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
corr_author: '1'
date_created: 2026-02-27T09:18:41Z
date_published: 2026-02-27T00:00:00Z
date_updated: 2026-07-27T14:30:07Z
day: '27'
ddc:
- '575'
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/AT-ISTA-21363
file:
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  checksum: de9145fa166a28c588b5184a2d3d4fee
  content_type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
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  date_created: 2026-02-27T09:11:33Z
  date_updated: 2026-02-27T09:11:33Z
  embargo: 2027-02-27
  embargo_to: open_access
  file_id: '21364'
  file_name: SupplementaryTables.xlsx
  file_size: 63749444
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  date_created: 2026-02-27T09:13:11Z
  date_updated: 2026-02-27T09:13:11Z
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file_date_updated: 2026-02-27T09:13:11Z
fulldoi: https://doi.org/10.15479/AT-ISTA-21363
has_accepted_license: '1'
month: '02'
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '21360'
    relation: used_in_publication
    status: public
status: public
title: 'Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating
  Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species'
tmp:
  image: /images/cc_by_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
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    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21980'
abstract:
- lang: eng
  text: Despite significant progress in the field of molecular electronics over the
    last two decades, the quantitative prediction of metal-molecule-metal junction
    conductance remains a challenge. The standard computational framework combines
    density functional theory (DFT) with nonequilibrium Green’s functions (NEGF) using
    low-rung exchange-correlation functionals such as PBE, which overestimate the
    conductances. More advanced correction methods exist but require complex workflows
    and high computational cost, limiting their accessibility. Here, we introduce
    a physically motivated approach that approximates results obtained with high-rung
    functionals. Our method fits the PBE-calculated transmission to a Breit-Wigner
    form and subsequently refines the fit parameters using molecular orbital energies
    and metal densities of states computed for the isolated subsystems with high-rung
    functionals. This approach is applicable to a broad range of molecular junctions
    yielding conductance values in quantitative agreement with experiments. Our approach
    is simple, low-cost, and accurate, making it well-suited for routine and large-scale
    prediction of single-molecule junction conductance.
acknowledgement: This work was supported primarily by the Institute of Science and
  Technology Austria. L.V. was supported in part by the National Science Foundation
  (No. NSF-DMR 2241180). Z.-F.L. was supported by an NSF CAREER Award, No. DMR-2044552
  and an Alfred P. Sloan Research Fellowship, No. FG-2024-21750.
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Artem
  full_name: Gulyaev, Artem
  id: 83ed7901-7380-11f0-bf20-a0788d5e654d
  last_name: Gulyaev
- first_name: Jyotisman
  full_name: Hazarika, Jyotisman
  id: d87714c4-663d-11f0-bd06-caece19833e5
  last_name: Hazarika
  orcid: 0009-0007-2542-7878
- first_name: Zhen-Fei
  full_name: Liu, Zhen-Fei
  last_name: Liu
- first_name: Latha
  full_name: Venkataraman, Latha
  id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
  last_name: Venkataraman
  orcid: 0000-0002-6957-6089
chemrxivid: 1
citation:
  ama: Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. A computationally efficient
    and accurate method for predicting conductance of single-molecule junctions. <i>Nano
    Letters</i>. 2026;26(22):7429–7434. doi:<a href="https://doi.org/10.1021/acs.nanolett.6c01462">10.1021/acs.nanolett.6c01462</a>
  apa: Gulyaev, A., Hazarika, J., Liu, Z.-F., &#38; Venkataraman, L. (2026). A computationally
    efficient and accurate method for predicting conductance of single-molecule junctions.
    <i>Nano Letters</i>. American Chemical Society. <a href="https://doi.org/10.1021/acs.nanolett.6c01462">https://doi.org/10.1021/acs.nanolett.6c01462</a>
  chicago: Gulyaev, Artem, Jyotisman Hazarika, Zhen-Fei Liu, and Latha Venkataraman.
    “A Computationally Efficient and Accurate Method for Predicting Conductance of
    Single-Molecule Junctions.” <i>Nano Letters</i>. American Chemical Society, 2026.
    <a href="https://doi.org/10.1021/acs.nanolett.6c01462">https://doi.org/10.1021/acs.nanolett.6c01462</a>.
  ieee: A. Gulyaev, J. Hazarika, Z.-F. Liu, and L. Venkataraman, “A computationally
    efficient and accurate method for predicting conductance of single-molecule junctions,”
    <i>Nano Letters</i>, vol. 26, no. 22. American Chemical Society, pp. 7429–7434,
    2026.
  ista: Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. 2026. A computationally efficient
    and accurate method for predicting conductance of single-molecule junctions. Nano
    Letters. 26(22), 7429–7434.
  mla: Gulyaev, Artem, et al. “A Computationally Efficient and Accurate Method for
    Predicting Conductance of Single-Molecule Junctions.” <i>Nano Letters</i>, vol.
    26, no. 22, American Chemical Society, 2026, pp. 7429–7434, doi:<a href="https://doi.org/10.1021/acs.nanolett.6c01462">10.1021/acs.nanolett.6c01462</a>.
  short: A. Gulyaev, J. Hazarika, Z.-F. Liu, L. Venkataraman, Nano Letters 26 (2026)
    7429–7434.
corr_author: '1'
das_tickbox: '1'
date_created: 2026-06-10T07:27:19Z
date_published: 2026-06-01T00:00:00Z
date_updated: 2026-07-28T09:57:28Z
day: '01'
ddc:
- '540'
department:
- _id: LaVe
- _id: GradSch
doi: 10.1021/acs.nanolett.6c01462
external_id:
  chemrxivid:
  - 10.26434/chemrxiv.15001696
  pmid:
  - '42223342'
file:
- access_level: open_access
  checksum: 897551374cac28e0db26dcb0b676b8e7
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-16T09:11:35Z
  date_updated: 2026-06-16T09:11:35Z
  file_id: '22013'
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  file_size: 3362800
  relation: main_file
  success: 1
file_date_updated: 2026-06-16T09:11:35Z
fulldoi: https://doi.org/10.1021/acs.nanolett.6c01462
has_accepted_license: '1'
intvolume: '        26'
issue: '22'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 7429–7434
pmid: 1
publication: Nano Letters
publication_identifier:
  eissn:
  - 1530-6992
  issn:
  - 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A computationally efficient and accurate method for predicting conductance
  of single-molecule junctions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '22404'
abstract:
- lang: eng
  text: We consider a class of two-dimensional tight binding models displaying conical
    intersections of the Bloch bands at the Fermi level. The setting includes the
    case of generic transitions between quantum Hall phases. We consider the longitudinal
    conductivity, as given by Kubo formula, describing the variation of the current
    after introducing a space-homogeneous electric field, in an adiabatic way. We
    obtain an explicit expression for the longitudinal conductivity, completely determined
    by the number of conical intersections and by the shape of the cones. In particular,
    the formula reproduces the known quantized values found for graphene and for the
    critical Haldane model. Furthermore, we discuss the validity of Kubo formula in
    presence of conical intersections in the spectrum, starting from the time-dependent
    Schrödinger equation. For electric fields which are weak and slowly varying in
    space and in time, we prove the validity of linear response from quantum dynamics.
acknowledgement: G. M. and M. P. acknowledge support by the European Research Council
  through the ERC-StG MaMBoQ, n. 802901. G. M. acknowledges financial support from
  the Independent Research Fund Denmark–Natural Sciences, grant DFF–10.46540/2032-00005B
  and from the European Research Council through the ERC CoG UniCoSM, grant agreement
  n.724939. M. P. acknowledges support from the MUR, PRIN 2022 project MaIQuFi cod.
  20223J85K3. This work has been carried out under the auspices of the GNFM of INdAM.
  We thank the anonymous referees for comments on a previous version of this manuscript.
article_number: '82'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Giovanna
  full_name: Marcelli, Giovanna
  last_name: Marcelli
- first_name: Lorenzo
  full_name: Pigozzi, Lorenzo
  id: efb8f850-3208-11ee-ac71-8c4f5803b9c6
  last_name: Pigozzi
- first_name: Marcello
  full_name: Porta, Marcello
  last_name: Porta
citation:
  ama: Marcelli G, Pigozzi L, Porta M. Longitudinal conductivity at integer quantum
    Hall transitions. <i>Letters in Mathematical Physics</i>. 2026;116(4). doi:<a
    href="https://doi.org/10.1007/s11005-026-02087-3">10.1007/s11005-026-02087-3</a>
  apa: Marcelli, G., Pigozzi, L., &#38; Porta, M. (2026). Longitudinal conductivity
    at integer quantum Hall transitions. <i>Letters in Mathematical Physics</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s11005-026-02087-3">https://doi.org/10.1007/s11005-026-02087-3</a>
  chicago: Marcelli, Giovanna, Lorenzo Pigozzi, and Marcello Porta. “Longitudinal
    Conductivity at Integer Quantum Hall Transitions.” <i>Letters in Mathematical
    Physics</i>. Springer Nature, 2026. <a href="https://doi.org/10.1007/s11005-026-02087-3">https://doi.org/10.1007/s11005-026-02087-3</a>.
  ieee: G. Marcelli, L. Pigozzi, and M. Porta, “Longitudinal conductivity at integer
    quantum Hall transitions,” <i>Letters in Mathematical Physics</i>, vol. 116, no.
    4. Springer Nature, 2026.
  ista: Marcelli G, Pigozzi L, Porta M. 2026. Longitudinal conductivity at integer
    quantum Hall transitions. Letters in Mathematical Physics. 116(4), 82.
  mla: Marcelli, Giovanna, et al. “Longitudinal Conductivity at Integer Quantum Hall
    Transitions.” <i>Letters in Mathematical Physics</i>, vol. 116, no. 4, 82, Springer
    Nature, 2026, doi:<a href="https://doi.org/10.1007/s11005-026-02087-3">10.1007/s11005-026-02087-3</a>.
  short: G. Marcelli, L. Pigozzi, M. Porta, Letters in Mathematical Physics 116 (2026).
das_tickbox: '1'
dataavailabilitystatement: Data sharing is not applicable to this article as no datasets
  were generated or analyzed during the current study.
date_created: 2026-07-26T22:01:40Z
date_published: 2026-08-01T00:00:00Z
date_updated: 2026-07-29T10:51:55Z
day: '01'
department:
- _id: RoSe
- _id: GradSch
doi: 10.1007/s11005-026-02087-3
external_id:
  arxiv:
  - '2503.01381'
fulldoi: https://doi.org/10.1007/s11005-026-02087-3
intvolume: '       116'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2503.01381
mathsc:
- 81V70
month: '08'
oa: 1
oa_version: Preprint
publication: Letters in Mathematical Physics
publication_identifier:
  eissn:
  - 1573-0530
  issn:
  - 0377-9017
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: not applicable
scopus_import: '1'
status: public
supplementarymaterial: no
title: Longitudinal conductivity at integer quantum Hall transitions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22607'
abstract:
- lang: eng
  text: "Farkas established that a system of linear inequalities has a solution if
    and only if we cannot obtain a contradiction by taking a linear combination of
    the inequalities. We state and formally prove several Farkas-like theorems over
    linearly ordered fields in Lean 4. Furthermore, we extend duality theory to the
    case when some coefficients are allowed to take \"infinite values\".\r\nCode:
    https://github.com/madvorak/duality/tree/v3.2.0"
acknowledgement: "We would like to thank David Bartl and Jasmin Blanchette for frequent
  consultations.\r\nWe would also like to express gratitude to Henrik Böving for a
  help with generalization\r\nfrom extended rationals to extended linearly ordered
  fields and to Andrew Yang for the\r\nproof of Finset.univ_sum_of_zero_when_not.
  We would also like to acknowledge Antoine\r\nChambert-Loir, Apurva Nakade, Yaël
  Dillies, Richard Copley, Edward van de Meent, Markus\r\nHimmel, Mario Carneiro,
  and Kevin Buzzard."
article_number: '14253'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Martin
  full_name: Dvorak, Martin
  id: 40ED02A8-C8B4-11E9-A9C0-453BE6697425
  last_name: Dvorak
  orcid: 0000-0001-5293-214X
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
citation:
  ama: Dvorak M, Kolmogorov V. Duality theory in linear optimization and its extensions
    -- formally verified. <i>Annals of Formalized Mathematics</i>. 2026;2. doi:<a
    href="https://doi.org/10.46298/afm.14253">10.46298/afm.14253</a>
  apa: Dvorak, M., &#38; Kolmogorov, V. (2026). Duality theory in linear optimization
    and its extensions -- formally verified. <i>Annals of Formalized Mathematics</i>.
    EPI Sciences. <a href="https://doi.org/10.46298/afm.14253">https://doi.org/10.46298/afm.14253</a>
  chicago: Dvorak, Martin, and Vladimir Kolmogorov. “Duality Theory in Linear Optimization
    and Its Extensions -- Formally Verified.” <i>Annals of Formalized Mathematics</i>.
    EPI Sciences, 2026. <a href="https://doi.org/10.46298/afm.14253">https://doi.org/10.46298/afm.14253</a>.
  ieee: M. Dvorak and V. Kolmogorov, “Duality theory in linear optimization and its
    extensions -- formally verified,” <i>Annals of Formalized Mathematics</i>, vol.
    2. EPI Sciences, 2026.
  ista: Dvorak M, Kolmogorov V. 2026. Duality theory in linear optimization and its
    extensions -- formally verified. Annals of Formalized Mathematics. 2, 14253.
  mla: Dvorak, Martin, and Vladimir Kolmogorov. “Duality Theory in Linear Optimization
    and Its Extensions -- Formally Verified.” <i>Annals of Formalized Mathematics</i>,
    vol. 2, 14253, EPI Sciences, 2026, doi:<a href="https://doi.org/10.46298/afm.14253">10.46298/afm.14253</a>.
  short: M. Dvorak, V. Kolmogorov, Annals of Formalized Mathematics 2 (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-07-29T09:06:55Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-07-29T10:50:17Z
day: '13'
ddc:
- '500'
department:
- _id: VlKo
- _id: GradSch
doi: 10.46298/afm.14253
external_id:
  arxiv:
  - '2409.08119'
fulldoi: https://doi.org/10.46298/afm.14253
has_accepted_license: '1'
intvolume: '         2'
keyword:
- Farkas lemma
- linear programming
- extended reals
- calculus of inductive constructions
language:
- iso: eng
mathsc:
- 68V20
- 15A39
- 90C05
month: '03'
oa_version: Published Version
publication: Annals of Formalized Mathematics
publication_identifier:
  eissn:
  - 3117-4604
publication_status: published
publisher: EPI Sciences
quality_controlled: '1'
related_material:
  record:
  - id: '20071'
    relation: earlier_version
    status: public
researchdata_availability: no
status: public
supplementarymaterial: no
title: Duality theory in linear optimization and its extensions -- formally verified
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2026'
...
---
OA_place: repository
_id: '21393'
abstract:
- lang: eng
  text: "This thesis documents a voyage towards truth and beauty via formal verification
    of theorems. To this end, we develop libraries in Lean 4 that present definitions
    and results from diverse areas of MathematiCS (i.e., Mathematics and Computer
    Science). The aim is to create code that is understandable, believable, useful,
    and elegant. The code should stand for itself as much as possible without a need
    for documentation; however, this text redundantly documents our code artifacts
    and provides additional context that isn’t present in the code. This thesis is
    written for readers who know Lean 4 but are not familiar with any of the topics
    presented. We manifest truth and beauty in three formalized areas of MathematiCS.\r\n\r\nWe
    formalize general grammars in Lean 4 and use grammars to show closure of the class
    of type-0 languages under four operations; union, reversal, concatenation, and
    the Kleene star.\r\n\r\nOur second stop is the theory of optimization. Farkas
    established that a system of linear inequalities has a solution if and only if
    we cannot obtain a contradiction by taking a linear combination of the inequalities.
    We state and formally prove several Farkas-like theorems over linearly ordered
    fields in Lean 4. Furthermore, we extend duality theory to the case when some
    coefficients are allowed to take “infinite values”. Additionally, we develop the
    basics of the theory of optimization in terms of the framework called General-Valued
    Constraint Satisfaction Problems, and we prove that, if a Rational-Valued Constraint
    Satisfaction Problem template has symmetric fractional polymorphisms of all arities,
    then its basic LP relaxation is tight.\r\n\r\nOur third stop is matroid theory.
    Seymour’s decomposition theorem is a hallmark result in matroid theory, presenting
    a structural characterization of the class of regular matroids. We aim to formally
    verify Seymour’s theorem in Lean 4. First, we build a library for working with
    totally unimodular matrices. We define binary matroids and their standard representations,
    and we prove that they form a matroid in the sense how Mathlib defines matroids.
    We define regular matroids to be matroids for which there exists a full representation
    rational matrix that is totally unimodular, and we prove that all regular matroids
    are binary. We define 1-sum, 2-sum, and 3 sum of binary matroids as specific ways
    to compose their standard representation matrices. We prove that the 1-sum, the
    2-sum, and the 3-sum of regular matroids are a regular matroid, which concludes
    the composition direction of the Seymour’s theorem. The (more difficult) decomposition
    direction remains unproved.\r\n\r\nIn the pursuit of truth, we focus on identifying
    the trusted code in each project and presenting it faithfully. We emphasize the
    readability and believability of definitions rather than choosing definitions
    that are easier to work with. In search for beauty, we focus on the philosophical
    framework of Roger Scruton, who emphasizes that beauty is not a mere decoration
    but, most importantly, beauty is the means for shaping our place in the world
    and a source of redemption, where it can be viewed as a substitute for religion."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Martin
  full_name: Dvorak, Martin
  id: 40ED02A8-C8B4-11E9-A9C0-453BE6697425
  last_name: Dvorak
  orcid: 0000-0001-5293-214X
citation:
  ama: 'Dvorak M. Pursuit of truth and beauty in Lean 4: Formally verified theory
    of grammars, optimization, matroids. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-21393">10.15479/AT-ISTA-21393</a>'
  apa: 'Dvorak, M. (2026). <i>Pursuit of truth and beauty in Lean 4: Formally verified
    theory of grammars, optimization, matroids</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT-ISTA-21393">https://doi.org/10.15479/AT-ISTA-21393</a>'
  chicago: 'Dvorak, Martin. “Pursuit of Truth and Beauty in Lean 4: Formally Verified
    Theory of Grammars, Optimization, Matroids.” Institute of Science and Technology
    Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21393">https://doi.org/10.15479/AT-ISTA-21393</a>.'
  ieee: 'M. Dvorak, “Pursuit of truth and beauty in Lean 4: Formally verified theory
    of grammars, optimization, matroids,” Institute of Science and Technology Austria,
    2026.'
  ista: 'Dvorak M. 2026. Pursuit of truth and beauty in Lean 4: Formally verified
    theory of grammars, optimization, matroids. Institute of Science and Technology
    Austria.'
  mla: 'Dvorak, Martin. <i>Pursuit of Truth and Beauty in Lean 4: Formally Verified
    Theory of Grammars, Optimization, Matroids</i>. Institute of Science and Technology
    Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21393">10.15479/AT-ISTA-21393</a>.'
  short: 'M. Dvorak, Pursuit of Truth and Beauty in Lean 4: Formally Verified Theory
    of Grammars, Optimization, Matroids, Institute of Science and Technology Austria,
    2026.'
corr_author: '1'
date_created: 2026-03-04T09:26:46Z
date_published: 2026-03-04T00:00:00Z
date_updated: 2026-07-29T12:56:52Z
day: '04'
ddc:
- '511'
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: VlKo
doi: 10.15479/AT-ISTA-21393
doi_confirm: '1'
file:
- access_level: open_access
  checksum: cface6dc18152680962b5361575f6e4f
  content_type: application/pdf
  creator: mdvorak
  date_created: 2026-03-04T08:56:15Z
  date_updated: 2026-03-04T08:56:15Z
  file_id: '21394'
  file_name: 2026_Dvorak_Martin_Thesis.pdf
  file_size: 1771231
  relation: main_file
  success: 1
- access_level: closed
  checksum: 290ddfacfb7e07fb07e6f0b334e67c90
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: mdvorak
  date_created: 2026-03-04T09:03:37Z
  date_updated: 2026-03-04T09:03:37Z
  file_id: '21395'
  file_name: 2026_Dvorak_Martin_Thesis.docx
  file_size: 864585
  relation: source_file
file_date_updated: 2026-03-04T09:03:37Z
fulldoi: https://doi.org/10.15479/AT-ISTA-21393
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '160'
publication_identifier:
  isbn:
  - 978-3-99078-074-9
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  link:
  - description: Full version of all definitions, statements, and proofs for Chapter
      3.1 (Linear duality)
    relation: software
    url: https://github.com/madvorak/duality/tree/v3.5.0
  - description: Full version of all definitions, statements, and proofs for Chapter
      3.2 (Valued Constraint Satisfaction Problems)
    relation: software
    url: https://github.com/madvorak/vcsp/tree/v8.2.0
  - description: Full version of all definitions, statements, and proofs for Chapter
      4 (Seymour project)
    relation: software
    url: https://github.com/Ivan-Sergeyev/seymour/tree/v1.2.0
  - description: Full version of all definitions, statements, and proofs for Chapter
      5 (Theory of grammars)
    relation: software
    url: https://github.com/madvorak/chomsky/tree/v1.2.0
  - description: Old version (Lean 3) of the project about grammars
    relation: software
    url: https://github.com/madvorak/grammars
  - description: Demonstration of (minimal) requirements for selected algebraic classes
      used in my Ph.D. thesis
    relation: software
    url: https://github.com/madvorak/preliminaries/blob/main/Preliminaries.lean
  record:
  - id: '13120'
    relation: part_of_dissertation
    status: public
  - id: '20071'
    relation: part_of_dissertation
    status: public
  - id: '21398'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Jasmin
  full_name: Blanchette, Jasmin
  last_name: Blanchette
title: 'Pursuit of truth and beauty in Lean 4: Formally verified theory of grammars,
  optimization, matroids'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22406'
abstract:
- lang: eng
  text: "It is known that for a uniform morphic sequence \U0001D496 =⟨\U0001D462\U0001D45B⟩∞\r\n\U0001D45B=0
    and an algebraic number \U0001D6FD such that |\U0001D6FD| >1, the number [[\U0001D496]]\U0001D6FD
    :=∑∞\r\n\U0001D45B=0(\U0001D462\U0001D45B/\U0001D6FD\U0001D45B) either lies in
    ℚ⁡(\U0001D6FD) or is transcendental. In this paper, we show a similar rational–transcendental
    dichotomy for sequences defined by irreducible Pisot morphisms on binary alphabets.
    Subject to the Pisot conjecture (an irreducible Pisot morphism has pure discrete
    spectrum), we generalise the latter result to arbitrary finite alphabets. In certain
    cases, we are able to show transcendence of [[\U0001D496]]\U0001D6FD outright.
    In particular, for \U0001D458 ≥2, if \U0001D496 is the k-Bonacci word, then [[\U0001D496]]\U0001D6FD
    is transcendental."
acknowledgement: "We thank the anonymous referee for identifying an error in an earlier\r\nversion
  of the paper. We gratefully acknowledge support from UKRI Frontier Research\r\nGrant
  EP/X033813/1, ERC grant DynAMiCS (101167561) and DFG grant 389792660 as\r\npart
  of TRR 248. J.O. is also affiliated with Keble College, Oxford as an Emmy Network\r\nfellow."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Pavol
  full_name: Kebis, Pavol
  id: 2e0132b3-4e98-11ef-b275-cf7281c2802a
  last_name: Kebis
- first_name: FLORIAN
  full_name: LUCA, FLORIAN
  last_name: LUCA
- first_name: JOEL
  full_name: OUAKNINE, JOEL
  last_name: OUAKNINE
- first_name: ANDREW
  full_name: SCOONES, ANDREW
  last_name: SCOONES
- first_name: JAMES
  full_name: WORRELL, JAMES
  last_name: WORRELL
citation:
  ama: Kebis P, LUCA F, OUAKNINE J, SCOONES A, WORRELL J. Transcendence for Pisot
    morphic words over an algebraic base. <i>Ergodic Theory and Dynamical Systems</i>.
    2026:1-22. doi:<a href="https://doi.org/10.1017/etds.2026.10324">10.1017/etds.2026.10324</a>
  apa: Kebis, P., LUCA, F., OUAKNINE, J., SCOONES, A., &#38; WORRELL, J. (2026). Transcendence
    for Pisot morphic words over an algebraic base. <i>Ergodic Theory and Dynamical
    Systems</i>. Cambridge University Press. <a href="https://doi.org/10.1017/etds.2026.10324">https://doi.org/10.1017/etds.2026.10324</a>
  chicago: Kebis, Pavol, FLORIAN LUCA, JOEL OUAKNINE, ANDREW SCOONES, and JAMES WORRELL.
    “Transcendence for Pisot Morphic Words over an Algebraic Base.” <i>Ergodic Theory
    and Dynamical Systems</i>. Cambridge University Press, 2026. <a href="https://doi.org/10.1017/etds.2026.10324">https://doi.org/10.1017/etds.2026.10324</a>.
  ieee: P. Kebis, F. LUCA, J. OUAKNINE, A. SCOONES, and J. WORRELL, “Transcendence
    for Pisot morphic words over an algebraic base,” <i>Ergodic Theory and Dynamical
    Systems</i>. Cambridge University Press, pp. 1–22, 2026.
  ista: Kebis P, LUCA F, OUAKNINE J, SCOONES A, WORRELL J. 2026. Transcendence for
    Pisot morphic words over an algebraic base. Ergodic Theory and Dynamical Systems.,
    1–22.
  mla: Kebis, Pavol, et al. “Transcendence for Pisot Morphic Words over an Algebraic
    Base.” <i>Ergodic Theory and Dynamical Systems</i>, Cambridge University Press,
    2026, pp. 1–22, doi:<a href="https://doi.org/10.1017/etds.2026.10324">10.1017/etds.2026.10324</a>.
  short: P. Kebis, F. LUCA, J. OUAKNINE, A. SCOONES, J. WORRELL, Ergodic Theory and
    Dynamical Systems (2026) 1–22.
das_tickbox: '0'
date_created: 2026-07-27T05:53:25Z
date_published: 2026-07-10T00:00:00Z
date_updated: 2026-08-03T06:17:50Z
day: '10'
ddc:
- '000'
department:
- _id: ToHe
- _id: GradSch
doi: 10.1017/etds.2026.10324
external_id:
  arxiv:
  - '2405.05279'
fulldoi: https://doi.org/10.1017/etds.2026.10324
has_accepted_license: '1'
keyword:
- balanced-pair algorithm
- Cobham’s conjecture
- k-Bonacci words
- Pisot conjecture
- subspace theorem
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1017/etds.2026.10324
mathsc:
- 11J81
- 37B10
- 11J87
month: '07'
oa: 1
oa_version: Published Version
page: 1-22
publication: Ergodic Theory and Dynamical Systems
publication_identifier:
  eissn:
  - 1469-4417
  issn:
  - 0143-3857
publication_status: epub_ahead
publisher: Cambridge University Press
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Transcendence for Pisot morphic words over an algebraic base
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '22619'
abstract:
- lang: eng
  text: Planar germanium is currently the only semiconducting platform where high-coherence
    spin qubits and proximity-induced superconductivity have each been demonstrated.
    Recent research into spin qubits in Ge/SiGe heterostructures has focused on increasing
    the thickness of the SiGe capping layer, reporting improvements in the electrostatic
    noise levels. Meanwhile, heterostructures with thinner capping layers remain rather
    unexplored, despite the potential advantages for proximity-induced superconductivity.
    Here, we study a Ge/SiGe heterostructure with a thin SiGe cap d - 4nm and investigate
    its viability to host low-noise quantum dots. To keep the thermal budget compatible
    with superconducting layers, low-temperature oxide deposition processes were developed
    and implemented for the gate dielectrics. The charge noise level of the fabricated
    devices is estimated to be 1.8  +- 1.0 μeV/ square HZ⁠, comparable to devices
    fabricated on shallow heterostructures (⁠ d - 20nm⁠) with high-temperature deposited
    oxides. Low charge noise levels, together with the straightforward integration
    of superconductors, make this heterostructure an attractive platform for prototyping
    hybrid semiconducting–superconducting devices.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
acknowledgement: 'We sincerely thank Nick van Loo, Greg Mazur, Dhananjay Joshi, and
  Srijit Goswami for their inputs on low-temperature HfOx deposition; Matias Urdampilleta
  and Daniel Jirovec for discussions; and Kristen Léonard for the careful reading
  of the manuscript. This research was supported by the Scientific Service Units of
  ISTA through resources provided by the Miba Machine Shop and the Nanofabrication
  facility. The authors acknowledge support from the NOMIS Foundation; the European
  Innovation Council Pathfinder Grant No. 101115315 (QuKiT); the FWF Projects with
  DOI:10.55776/F86, DOI:10.55776/PAT7682124, and DOI:10.55776/P36507; and the HE-MSCA-PF
  project with DOI:10.3030/101150858. ICN2 is supported by the Severo Ochoa Program
  from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and is funded by the CERCA Program/Generalitat
  de Catalunya. ICN2 acknowledges funding from Generalitat de Catalunya (No. 2021SGR00457).
  We acknowledge support from the CSIC Interdisciplinary Thematic Platform (PTI+)
  on Quantum Technologies (PTI-QTEP+).'
article_number: '033505'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Maksim
  full_name: Borovkov, Maksim
  id: 1fd0975f-8b61-11ed-b69e-d149334f28c5
  last_name: Borovkov
- first_name: Yona A
  full_name: Schell, Yona A
  id: fe39122d-06bb-11ec-a33b-9e22b40e40a5
  last_name: Schell
- first_name: Dina
  full_name: Sokolova, Dina
  id: 2d2d62f8-72f0-11ef-b75a-8ec3e8a60032
  last_name: Sokolova
- first_name: Kevin Etienne Robert
  full_name: Roux, Kevin Etienne Robert
  id: 53f93ea2-803f-11ed-ab7e-b283135794ef
  last_name: Roux
- first_name: Paul
  full_name: Falthansl-Scheinecker, Paul
  id: 85b43b21-15b2-11ec-abd3-e2c252cc2285
  last_name: Falthansl-Scheinecker
- first_name: Giorgio
  full_name: Fabris, Giorgio
  id: 298cf6f3-1ff6-11ee-9fa6-d94cfa0b3352
  last_name: Fabris
- first_name: Devashish C
  full_name: Shah, Devashish C
  id: de191434-4e7e-11ef-bf4b-9a056fc19fc3
  last_name: Shah
  orcid: 0009-0007-5829-7707
- first_name: Jaime
  full_name: Saez Mollejo, Jaime
  id: e0390f72-f6e0-11ea-865d-862393336714
  last_name: Saez Mollejo
- first_name: Rodolfo
  full_name: Previdi, Rodolfo
  id: bc4ea1dc-00ce-11ec-8a4e-b325ca8b9876
  last_name: Previdi
- first_name: Inas
  full_name: Taha, Inas
  last_name: Taha
- first_name: Aziz
  full_name: Genç, Aziz
  last_name: Genç
- first_name: Jordi
  full_name: Arbiol, Jordi
  last_name: Arbiol
- first_name: Stefano
  full_name: Calcaterra, Stefano
  last_name: Calcaterra
- first_name: Afonso De Cerdeira
  full_name: Oliveira, Afonso De Cerdeira
  last_name: Oliveira
- first_name: Daniel
  full_name: Chrastina, Daniel
  last_name: Chrastina
- first_name: Giovanni
  full_name: Isella, Giovanni
  last_name: Isella
- first_name: Anton
  full_name: Bubis, Anton
  id: 1f6212b5-f795-11ec-9c0c-de4780302890
  last_name: Bubis
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
citation:
  ama: Borovkov M, Schell YA, Sokolova D, et al. Low-noise quantum dots in ultra-shallow
    Ge/SiGe heterostructures for prototyping hybrid semiconducting–superconducting
    devices. <i>Applied Physics Letters</i>. 2026;129(3). doi:<a href="https://doi.org/10.1063/5.0333142">10.1063/5.0333142</a>
  apa: Borovkov, M., Schell, Y. A., Sokolova, D., Roux, K. E. R., Falthansl-Scheinecker,
    P., Fabris, G., … Katsaros, G. (2026). Low-noise quantum dots in ultra-shallow
    Ge/SiGe heterostructures for prototyping hybrid semiconducting–superconducting
    devices. <i>Applied Physics Letters</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0333142">https://doi.org/10.1063/5.0333142</a>
  chicago: Borovkov, Maksim, Yona A Schell, Dina Sokolova, Kevin Etienne Robert Roux,
    Paul Falthansl-Scheinecker, Giorgio Fabris, Devashish C Shah, et al. “Low-Noise
    Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures for Prototyping Hybrid
    Semiconducting–Superconducting Devices.” <i>Applied Physics Letters</i>. AIP Publishing,
    2026. <a href="https://doi.org/10.1063/5.0333142">https://doi.org/10.1063/5.0333142</a>.
  ieee: M. Borovkov <i>et al.</i>, “Low-noise quantum dots in ultra-shallow Ge/SiGe
    heterostructures for prototyping hybrid semiconducting–superconducting devices,”
    <i>Applied Physics Letters</i>, vol. 129, no. 3. AIP Publishing, 2026.
  ista: Borovkov M, Schell YA, Sokolova D, Roux KER, Falthansl-Scheinecker P, Fabris
    G, Shah DC, Saez Mollejo J, Previdi R, Taha I, Genç A, Arbiol J, Calcaterra S,
    Oliveira ADC, Chrastina D, Isella G, Bubis A, Katsaros G. 2026. Low-noise quantum
    dots in ultra-shallow Ge/SiGe heterostructures for prototyping hybrid semiconducting–superconducting
    devices. Applied Physics Letters. 129(3), 033505.
  mla: Borovkov, Maksim, et al. “Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting–Superconducting Devices.” <i>Applied Physics
    Letters</i>, vol. 129, no. 3, 033505, AIP Publishing, 2026, doi:<a href="https://doi.org/10.1063/5.0333142">10.1063/5.0333142</a>.
  short: M. Borovkov, Y.A. Schell, D. Sokolova, K.E.R. Roux, P. Falthansl-Scheinecker,
    G. Fabris, D.C. Shah, J. Saez Mollejo, R. Previdi, I. Taha, A. Genç, J. Arbiol,
    S. Calcaterra, A.D.C. Oliveira, D. Chrastina, G. Isella, A. Bubis, G. Katsaros,
    Applied Physics Letters 129 (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: The data that support the findings of this study are openly
  available in Institute of Science and Technology repository at http://doi.org/10.15479/AT-ISTA-22242,
  Ref. 50.
date_created: 2026-08-02T22:01:53Z
date_published: 2026-07-20T00:00:00Z
date_updated: 2026-08-03T11:08:39Z
day: '20'
department:
- _id: GeKa
- _id: GradSch
- _id: NanoFab
doi: 10.1063/5.0333142
external_id:
  arxiv:
  - '2602.21363'
fulldoi: https://doi.org/10.1063/5.0333142
intvolume: '       129'
issue: '3'
language:
- iso: eng
main_file_link:
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month: '07'
oa: 1
oa_version: Preprint
project:
- _id: bdc2ca30-d553-11ed-ba76-cf164a5bb811
  grant_number: '101115315'
  name: Quantum bits with Kitaev Transmons
- _id: 34a66131-11ca-11ed-8bc3-a31681c6b03e
  grant_number: F8606
  name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems:
    Conventional  and unconventional topological superconductors'
- _id: 5b9e579c-ab3d-11f0-914f-88754c5b5a3f
  grant_number: PAT 7682124
  name: Superconducting spin qubits in planar Ge
- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
  grant_number: P36507
  name: Merging spin and superconducting qubits in planar Ge
- _id: 8ea8abf7-16d5-11f0-9cad-c41e56ec8bb3
  grant_number: '101150858'
  name: Realization and Manipulation of a Planar hybrid superconducting Andreev spin
    qubit in Germanium
publication: Applied Physics Letters
publication_identifier:
  eissn:
  - 1077-3118
  issn:
  - 0003-6951
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
related_material:
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researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Low-noise quantum dots in ultra-shallow Ge/SiGe heterostructures for prototyping
  hybrid semiconducting–superconducting devices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 129
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '22618'
abstract:
- lang: eng
  text: "We use a function field version of the circle method to prove that a positive
    proportion of elements in \U0001D53D\U0001D45E⁡[\U0001D461] are representable
    as a sum of three cubes of minimal degree from \U0001D53D\U0001D45E⁡[\U0001D461],
    assuming a suitable form of the Ratios Conjecture and that char⁡(\U0001D53D\U0001D45E)
    >3. The analogue of this conjecture for quadratic Dirichlet L-functions is known
    for large fixed q, via recent developments in homological stability."
acknowledgement: While working on this paper the first two authors were supported
  by FWF grant (DOI 10.55776/P36278) and the third author was supported by the European
  Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie
  Grant Agreement No. 101034413, and by the National Science and Technology Council
  Project Grant 114-2115-M-001-010-MY2.
article_number: e112
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Jakob
  full_name: Glas, Jakob
  id: d6423cba-dc74-11ea-a0a7-ee61689ff5fb
  last_name: Glas
- first_name: Victor
  full_name: Wang, Victor
  id: 76096395-aea4-11ed-a680-ab8ebbd3f1b9
  last_name: Wang
  orcid: 0000-0002-0704-7026
citation:
  ama: Browning TD, Glas J, Wang V. Sums of three cubes over a function field. <i>Forum
    of Mathematics Sigma</i>. 2026;14. doi:<a href="https://doi.org/10.1017/fms.2026.10259">10.1017/fms.2026.10259</a>
  apa: Browning, T. D., Glas, J., &#38; Wang, V. (2026). Sums of three cubes over
    a function field. <i>Forum of Mathematics Sigma</i>. Cambridge University Press.
    <a href="https://doi.org/10.1017/fms.2026.10259">https://doi.org/10.1017/fms.2026.10259</a>
  chicago: Browning, Timothy D, Jakob Glas, and Victor Wang. “Sums of Three Cubes
    over a Function Field.” <i>Forum of Mathematics Sigma</i>. Cambridge University
    Press, 2026. <a href="https://doi.org/10.1017/fms.2026.10259">https://doi.org/10.1017/fms.2026.10259</a>.
  ieee: T. D. Browning, J. Glas, and V. Wang, “Sums of three cubes over a function
    field,” <i>Forum of Mathematics Sigma</i>, vol. 14. Cambridge University Press,
    2026.
  ista: Browning TD, Glas J, Wang V. 2026. Sums of three cubes over a function field.
    Forum of Mathematics Sigma. 14, e112.
  mla: Browning, Timothy D., et al. “Sums of Three Cubes over a Function Field.” <i>Forum
    of Mathematics Sigma</i>, vol. 14, e112, Cambridge University Press, 2026, doi:<a
    href="https://doi.org/10.1017/fms.2026.10259">10.1017/fms.2026.10259</a>.
  short: T.D. Browning, J. Glas, V. Wang, Forum of Mathematics Sigma 14 (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-02T22:01:52Z
date_published: 2026-07-22T00:00:00Z
date_updated: 2026-08-03T12:13:59Z
day: '22'
ddc:
- '500'
department:
- _id: TiBr
- _id: GradSch
doi: 10.1017/fms.2026.10259
ec_funded: 1
external_id:
  arxiv:
  - '2402.07146'
file:
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  date_created: 2026-08-03T12:12:03Z
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  file_name: 2026_ForumMathematics_Browning.pdf
  file_size: 810718
  relation: main_file
  success: 1
file_date_updated: 2026-08-03T12:12:03Z
fulldoi: https://doi.org/10.1017/fms.2026.10259
has_accepted_license: '1'
intvolume: '        14'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: bd8a4fdc-d553-11ed-ba76-80a0167441a3
  grant_number: P36278
  name: Rational curves via function field analytic number theory
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Forum of Mathematics Sigma
publication_identifier:
  eissn:
  - 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Sums of three cubes over a function field
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2026'
...
---
OA_place: repository
_id: '22242'
abstract:
- lang: eng
  text: This deposit contains the data and analysis code accompanying the publication
    "Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures for Prototyping
    Hybrid Semiconducting–Superconducting Devices" (Borovkov et al.). The deposit
    includes the raw transport and current-noise measurements of three gate-defined
    quantum-dot devices as QCodes SQLite databases, the master table of the charge-noise
    (flank-method) analysis with the pointers linking every analyzed PSD trace to
    the raw data, the toy-model noise simulation datasets behind the supplementary
    figures, the archived analysis figures (PSD fits and lever-arm extractions), and
    the Python code reproducing the full analysis and all figures. The code is also
    maintained at https://github.com/ISTA-Nanoelectronics/noise_paper_public; instructions
    are provided in the README files.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
article_processing_charge: No
author:
- first_name: Maksim
  full_name: Borovkov, Maksim
  id: 1fd0975f-8b61-11ed-b69e-d149334f28c5
  last_name: Borovkov
citation:
  ama: Borovkov M. Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting-Superconducting Devices. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22242">10.15479/AT-ISTA-22242</a>
  apa: Borovkov, M. (2026). Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting-Superconducting Devices. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22242">https://doi.org/10.15479/AT-ISTA-22242</a>
  chicago: Borovkov, Maksim. “Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting-Superconducting Devices.” Institute of Science
    and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22242">https://doi.org/10.15479/AT-ISTA-22242</a>.
  ieee: M. Borovkov, “Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting-Superconducting Devices.” Institute of Science
    and Technology Austria, 2026.
  ista: Borovkov M. 2026. Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting-Superconducting Devices, Institute of Science
    and Technology Austria, <a href="https://doi.org/10.15479/AT-ISTA-22242">10.15479/AT-ISTA-22242</a>.
  mla: Borovkov, Maksim. <i>Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures
    for Prototyping Hybrid Semiconducting-Superconducting Devices</i>. Institute of
    Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22242">10.15479/AT-ISTA-22242</a>.
  short: M. Borovkov, (2026).
contributor:
- contributor_type: contact_person
  first_name: Maksim
  id: 1fd0975f-8b61-11ed-b69e-d149334f28c5
  last_name: Borovkov
corr_author: '1'
date_created: 2026-07-04T17:32:27Z
date_published: 2026-07-04T00:00:00Z
date_updated: 2026-08-03T11:08:38Z
day: '04'
ddc:
- '530'
department:
- _id: GradSch
- _id: GeKa
doi: 10.15479/AT-ISTA-22242
doi_confirm: '1'
file:
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  checksum: 2a1ea297e01a7a202a6b144d69a46eef
  content_type: application/x-zip-compressed
  creator: mborovko
  date_created: 2026-07-04T17:28:49Z
  date_updated: 2026-07-04T17:28:49Z
  file_id: '22243'
  file_name: noise_paper_public_deposit.zip
  file_size: 3082596099
  relation: main_file
  success: 1
file_date_updated: 2026-07-04T17:28:49Z
fulldoi: https://doi.org/10.15479/AT-ISTA-22242
has_accepted_license: '1'
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: bdc2ca30-d553-11ed-ba76-cf164a5bb811
  grant_number: '101115315'
  name: Quantum bits with Kitaev Transmons
- _id: 34a66131-11ca-11ed-8bc3-a31681c6b03e
  grant_number: F8606
  name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems:
    Conventional  and unconventional topological superconductors'
- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
  grant_number: P36507
  name: Merging spin and superconducting qubits in planar Ge
- _id: 8ea8abf7-16d5-11f0-9cad-c41e56ec8bb3
  grant_number: '101150858'
  name: Realization and Manipulation of a Planar hybrid superconducting Andreev spin
    qubit in Germanium
- _id: 5b9e579c-ab3d-11f0-914f-88754c5b5a3f
  grant_number: PAT 7682124
  name: Superconducting spin qubits in planar Ge
publisher: Institute of Science and Technology Austria
related_material:
  link:
  - relation: research_data
    url: https://github.com/ISTA-Nanoelectronics/noise_paper_public
  record:
  - id: '22619'
    relation: used_in_publication
    status: public
status: public
title: Low-Noise Quantum Dots in Ultra-Shallow Ge/SiGe Heterostructures for Prototyping
  Hybrid Semiconducting-Superconducting Devices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22645'
abstract:
- lang: eng
  text: Nanocrystal superlattices are commonly formed by changing concentration, solvent
    conditions, or particle surface chemistry. Although effective, these approaches
    alter multiple contributions to the interparticle potential simultaneously, making
    it difficult to isolate the interactions responsible for ordering or to control
    assembly in chemically complex environments. Here, we show that oligomeric species
    present in a nanocrystal reaction medium drive superlattice formation through
    a depletion mechanism. Using PbTe nanocrystals as a model system, we identify
    Pb–oleate oligomers in the crude reaction mixture, characterize their solution
    structure, and quantify their contribution to the interparticle potential, establishing
    depletion as the dominant short-range interaction governing spontaneous body-centered
    cubic superlattice formation. We then confirm the depletion origin of ordering
    by showing that varying depletant concentration predictably shifts the order–disorder
    boundary and produces a thermally reversible transition between dispersed and
    ordered states ─ behavior that is inconsistent with van der Waals or ligand-mediated
    mechanisms but is a direct consequence of depletion control. Having established
    and validated the mechanism, we demonstrate that the same depletion framework
    can be deliberately activated in purified dispersions and transferred across nanocrystal
    systems of different composition and shape, including anisotropic and binary assemblies.
    These results establish precursor-derived depletion as a general and chemically
    grounded mechanism for nanocrystal superlattice formation, and show that collective
    ordering can be programmed through the surrounding medium rather than through
    particle surface modification.
acknowledged_ssus:
- _id: EM-Fac
- _id: NMR
- _id: LifeSc
acknowledgement: ISTA and the Werner Siemens Foundation financially supported this
  work. The Scientific Service Units (SSU) of ISTA supported this research through
  resources provided by the Electron Microscopy Facility (EMF), NMR Facility, and
  the Lab Support Facility (LSF). M.E. acknowledges financial support from Deutsche
  Forschungsgemeinschaft through Collaborative Research Centre 1411. We thank Dr.
  Tommaso Constanzo and Tobias Kleinhanns for assistance with high-quality electron
  microscope image acquisition, Dr. Jeonghyun Park for providing NCs, Dr. Mariano
  Calcabrini for assistance with the NMR study, and Prof. Jonathan De Roo for fruitful
  discussions. This work benefited from the use of the SasView application, originally
  developed under NSF award DMR-0520547. SasView contains code developed with funding
  from the European Union’s Horizon 2020 research and innovation program under the
  SINE2020 project, grant agreement No. 654000.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Seungho
  full_name: Lee, Seungho
  id: BB243B88-D767-11E9-B658-BC13E6697425
  last_name: Lee
  orcid: 0000-0002-6962-8598
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Aiswarya
  full_name: Rayaroth Puthiyaveettil, Aiswarya
  id: 8aceb01b-8972-11ed-ae7b-d5fe53775add
  last_name: Rayaroth Puthiyaveettil
- first_name: Sharona
  full_name: Horta, Sharona
  id: 03a7e858-01b1-11ec-8b71-99ae6c4a05bc
  last_name: Horta
- first_name: Carl Peter
  full_name: Goodrich, Carl Peter
  id: EB352CD2-F68A-11E9-89C5-A432E6697425
  last_name: Goodrich
  orcid: 0000-0002-1307-5074
- first_name: Michael
  full_name: Engel, Michael
  last_name: Engel
- first_name: Ihor
  full_name: Cherniukh, Ihor
  id: d03b62b2-5976-11ef-a8d7-9525504b7895
  last_name: Cherniukh
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
citation:
  ama: Lee S, Balazs D, Rayaroth Puthiyaveettil A, et al. Reaction medium asan architect
    of nanocrystal superlattices. <i>Journal of the AmericanChemical Society</i>.
    2026;148(29):31245-31252. doi:<a href="https://doi.org/10.1021/jacs.6c07859">10.1021/jacs.6c07859</a>
  apa: Lee, S., Balazs, D., Rayaroth Puthiyaveettil, A., Horta, S., Goodrich, C. P.,
    Engel, M., … Ibáñez, M. (2026). Reaction medium asan architect of nanocrystal
    superlattices. <i>Journal of the AmericanChemical Society</i>. American Chemical
    Society. <a href="https://doi.org/10.1021/jacs.6c07859">https://doi.org/10.1021/jacs.6c07859</a>
  chicago: Lee, Seungho, Daniel Balazs, Aiswarya Rayaroth Puthiyaveettil, Sharona
    Horta, Carl Peter Goodrich, Michael Engel, Ihor Cherniukh, and Maria Ibáñez. “Reaction
    Medium Asan Architect of Nanocrystal Superlattices.” <i>Journal of the AmericanChemical
    Society</i>. American Chemical Society, 2026. <a href="https://doi.org/10.1021/jacs.6c07859">https://doi.org/10.1021/jacs.6c07859</a>.
  ieee: S. Lee <i>et al.</i>, “Reaction medium asan architect of nanocrystal superlattices,”
    <i>Journal of the AmericanChemical Society</i>, vol. 148, no. 29. American Chemical
    Society, pp. 31245–31252, 2026.
  ista: Lee S, Balazs D, Rayaroth Puthiyaveettil A, Horta S, Goodrich CP, Engel M,
    Cherniukh I, Ibáñez M. 2026. Reaction medium asan architect of nanocrystal superlattices.
    Journal of the AmericanChemical Society. 148(29), 31245–31252.
  mla: Lee, Seungho, et al. “Reaction Medium Asan Architect of Nanocrystal Superlattices.”
    <i>Journal of the AmericanChemical Society</i>, vol. 148, no. 29, American Chemical
    Society, 2026, pp. 31245–52, doi:<a href="https://doi.org/10.1021/jacs.6c07859">10.1021/jacs.6c07859</a>.
  short: S. Lee, D. Balazs, A. Rayaroth Puthiyaveettil, S. Horta, C.P. Goodrich, M.
    Engel, I. Cherniukh, M. Ibáñez, Journal of the AmericanChemical Society 148 (2026)
    31245–31252.
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-04T06:29:31Z
date_published: 2026-07-15T00:00:00Z
date_updated: 2026-08-04T06:47:13Z
day: '15'
ddc:
- '540'
department:
- _id: MaIb
- _id: LifeSc
- _id: GradSch
- _id: CaGo
doi: 10.1021/jacs.6c07859
external_id:
  pmid:
  - '42532904'
file:
- access_level: open_access
  checksum: 063314ae5ac4225ebd4436aa8707d113
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-04T06:40:17Z
  date_updated: 2026-08-04T06:40:17Z
  file_id: '22646'
  file_name: 2026_JACS_Lee.pdf
  file_size: 6564594
  relation: main_file
  success: 1
file_date_updated: 2026-08-04T06:40:17Z
fulldoi: https://doi.org/10.1021/jacs.6c07859
has_accepted_license: '1'
intvolume: '       148'
issue: '29'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 31245-31252
pmid: 1
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: Journal of the AmericanChemical Society
publication_identifier:
  eissn:
  - 1520-5126
  issn:
  - 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Reaction medium asan architect of nanocrystal superlattices
tmp:
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 148
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22642'
abstract:
- lang: eng
  text: Continuously operating atom-light interfaces represent a key prerequisite
    for steady-state quantum sensors and efficient quantum processors. Here, we demonstrate
    continuous accumulation of sub-Doppler-cooled atoms in a shallow intracavity dipole
    trap, realizing this regime. The key ingredient is a light-shift manipulation
    that creates spatially varying cooling parameters, enabling efficient capture
    and accumulation of atoms within a cavity mode. Demonstrated with rubidium atoms,
    a continuous flux from a source cell is funneled through the magneto-optical trap
    into the cavity mode, where the atoms are cooled and maintained below 10µK in
    steady state without time-sequenced operation. We characterize the resulting continuously
    maintained ensemble of millions of atoms and its collective coupling to the cavity
    field, establishing a route toward continuously operated cavity-QED systems and
    long-duration atomic and hybrid quantum sensors.
acknowledgement: "The authors thank Vyacheslav Li for his earlier contributions to
  the development of the setup utilized in this work.\r\nThis work was supported by
  the Institute of Science and Technology Austria (ISTA); E.G. was supported by the
  European Research Council under Grant No. 101087907 (ERC CoG\r\nQuHAMP)."
article_number: '023302'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Edward-Fulbright
  full_name: Gheorghita, Edward-Fulbright
  id: e664a051-133f-11ed-8f02-a05999ad0822
  last_name: Gheorghita
- first_name: Sebastian
  full_name: Wald, Sebastian
  id: 133F200A-B015-11E9-AD41-0EDAE5697425
  last_name: Wald
  orcid: 0000-0002-5869-1604
- first_name: Andrea
  full_name: Pupić, Andrea
  id: ef9c50a4-5335-11ef-8b9b-8ce03e6380ed
  last_name: Pupić
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
citation:
  ama: Gheorghita E-F, Wald S, Pupić A, Hosten O. Continuous accumulation of cold
    atoms in an optical cavity. <i>Physical Review A</i>. 2026;114(2). doi:<a href="https://doi.org/10.1103/71f2-sq4p">10.1103/71f2-sq4p</a>
  apa: Gheorghita, E.-F., Wald, S., Pupić, A., &#38; Hosten, O. (2026). Continuous
    accumulation of cold atoms in an optical cavity. <i>Physical Review A</i>. American
    Physical Society. <a href="https://doi.org/10.1103/71f2-sq4p">https://doi.org/10.1103/71f2-sq4p</a>
  chicago: Gheorghita, Edward-Fulbright, Sebastian Wald, Andrea Pupić, and Onur Hosten.
    “Continuous Accumulation of Cold Atoms in an Optical Cavity.” <i>Physical Review
    A</i>. American Physical Society, 2026. <a href="https://doi.org/10.1103/71f2-sq4p">https://doi.org/10.1103/71f2-sq4p</a>.
  ieee: E.-F. Gheorghita, S. Wald, A. Pupić, and O. Hosten, “Continuous accumulation
    of cold atoms in an optical cavity,” <i>Physical Review A</i>, vol. 114, no. 2.
    American Physical Society, 2026.
  ista: Gheorghita E-F, Wald S, Pupić A, Hosten O. 2026. Continuous accumulation of
    cold atoms in an optical cavity. Physical Review A. 114(2), 023302.
  mla: Gheorghita, Edward-Fulbright, et al. “Continuous Accumulation of Cold Atoms
    in an Optical Cavity.” <i>Physical Review A</i>, vol. 114, no. 2, 023302, American
    Physical Society, 2026, doi:<a href="https://doi.org/10.1103/71f2-sq4p">10.1103/71f2-sq4p</a>.
  short: E.-F. Gheorghita, S. Wald, A. Pupić, O. Hosten, Physical Review A 114 (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: "There are no publicly available research data or software\r\nsupporting
  this manuscript. Requests for further information\r\nor data should be sent to the
  authors."
date_created: 2026-08-04T05:58:23Z
date_published: 2026-08-03T00:00:00Z
date_updated: 2026-08-04T06:07:20Z
day: '03'
ddc:
- '530'
department:
- _id: OnHo
- _id: GradSch
doi: 10.1103/71f2-sq4p
external_id:
  arxiv:
  - '2512.14528'
file:
- access_level: open_access
  checksum: fdecc394b734b56e1b3b151a816bbe14
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-04T06:03:14Z
  date_updated: 2026-08-04T06:03:14Z
  file_id: '22643'
  file_name: 2026_PhysicalReviewA_Gheorghita.pdf
  file_size: 959463
  relation: main_file
  success: 1
file_date_updated: 2026-08-04T06:03:14Z
fulldoi: https://doi.org/10.1103/71f2-sq4p
has_accepted_license: '1'
intvolume: '       114'
issue: '2'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: bdb2a702-d553-11ed-ba76-f12e3e5a3bc6
  grant_number: '101087907'
  name: 'A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational
    quantum mechanics'
publication: Physical Review A
publication_identifier:
  eissn:
  - 2469-9934
  issn:
  - 2469-9926
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
researchdata_availability: upon request
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Continuous accumulation of cold atoms in an optical cavity
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '22647'
abstract:
- lang: eng
  text: "Within the plant endomembrane system, the vesicle coat protein clathrin localizes
    to the plasma membrane (PM) and the trans-Golgi Network/early endosome (TGN/EE).
    While the role of clathrin in endocytosis at the PM is well established, its function
    at TGN/EE, presumably in late secretion (trafficking from the TGN/EE to the cell
    surface) or en route to the vacuole, is debated. Similarly debated are potential
    homeostatic mechanisms balancing the trafficking routes, especially endocytosis
    and late secretion.\r\nWe address these questions in Arabidopsis thaliana using
    conditional silencing of CLATHRIN HEAVY CHAIN (CHC), conditional overexpression
    of the clathrin uncoating factor AUXILIN-LIKE1, and secretory mutants.\r\nCHC
    silencing interferes with trafficking of cargoes destined for the apoplast and
    the PM, supporting a function of clathrin in late secretion. The secretory cargoes
    become abnormally rerouted from the TGN/EE to the vacuole. Unlike CHC silencing,
    overexpression of AUXILIN-LIKE1 selectively inhibits clathrin-mediated endocytosis
    while secretion continues normally at early points of induction. Conversely, secretory
    mutants exhibit a reduced PM recruitment of clathrin, and variably, of the TPLATE
    endocytic component.\r\nTogether, our data show a role of clathrin in secretion
    and suggest secretion as a fundamental trafficking process to which endocytosis
    is adjusted by a weak homeostatic mechanism."
acknowledgement: 'The authors wish to acknowledge Dr. Paweł Baster for cloning PIN1-GFP-2/pDONR221,
  Ms. Aline Monzer and Dr. Mingyue Li for help with CHC protein level evaluation,
  Dr. Michał Rychłowski for help with confocal microscopy, Prof. Ari Pekka Mähönen
  for sharing the p1R4-pUBQ10:XVE plasmid, and Prof. Ying Gu for sharing seeds of
  the sec5 mutant. M.A. would like to thank Dr. Xixi Zhang and Prof. Sebastian Bednarek
  for inspiring discussions. This work was supported by the Taif University Researchers
  Supporting Project, TURSP-HC2022/02 to JF and SA and Austrian Science Fund (FWF):
  I 3630-B25 to JF. Open Access funding provided by Institute of Science and Technology
  Austria.'
article_number: nph.71454
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Maciek
  full_name: Adamowski, Maciek
  id: 45F536D2-F248-11E8-B48F-1D18A9856A87
  last_name: Adamowski
  orcid: 0000-0001-6463-5257
- first_name: Adam
  full_name: Gackowski, Adam
  last_name: Gackowski
- first_name: Ivana
  full_name: Matijevic, Ivana
  id: 83c17ce3-15b2-11ec-abd3-f486545870bd
  last_name: Matijevic
- first_name: Saqer S.
  full_name: Alotaibi, Saqer S.
  last_name: Alotaibi
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Adamowski M, Gackowski A, Matijevic I, Alotaibi SS, Friml J. The role of clathrin
    in post‐Golgi secretion in plant cells. <i>New Phytologist</i>. 2026. doi:<a href="https://doi.org/10.1111/nph.71454">10.1111/nph.71454</a>
  apa: Adamowski, M., Gackowski, A., Matijevic, I., Alotaibi, S. S., &#38; Friml,
    J. (2026). The role of clathrin in post‐Golgi secretion in plant cells. <i>New
    Phytologist</i>. Wiley. <a href="https://doi.org/10.1111/nph.71454">https://doi.org/10.1111/nph.71454</a>
  chicago: Adamowski, Maciek, Adam Gackowski, Ivana Matijevic, Saqer S. Alotaibi,
    and Jiří Friml. “The Role of Clathrin in Post‐Golgi Secretion in Plant Cells.”
    <i>New Phytologist</i>. Wiley, 2026. <a href="https://doi.org/10.1111/nph.71454">https://doi.org/10.1111/nph.71454</a>.
  ieee: M. Adamowski, A. Gackowski, I. Matijevic, S. S. Alotaibi, and J. Friml, “The
    role of clathrin in post‐Golgi secretion in plant cells,” <i>New Phytologist</i>.
    Wiley, 2026.
  ista: Adamowski M, Gackowski A, Matijevic I, Alotaibi SS, Friml J. 2026. The role
    of clathrin in post‐Golgi secretion in plant cells. New Phytologist., nph. 71454.
  mla: Adamowski, Maciek, et al. “The Role of Clathrin in Post‐Golgi Secretion in
    Plant Cells.” <i>New Phytologist</i>, nph. 71454, Wiley, 2026, doi:<a href="https://doi.org/10.1111/nph.71454">10.1111/nph.71454</a>.
  short: M. Adamowski, A. Gackowski, I. Matijevic, S.S. Alotaibi, J. Friml, New Phytologist
    (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: 'Original data associated with this study have been deposited
  in Dataset S1. The accession nos. of A. thaliana genes used in this study are as
  follows: CHC1 (AT3G11130), CHC2 (AT3G08530), CLC2 (AT2G40060), TPLATE (AT3G01780),
  AP2A1 (AT5G22770), DRP1C (AT1G14830), GNOM-LIKE1 (AT5G39500), BEN3/BIG2 (AT3G60860),
  TMK4 (AT3G23750), PIN1 (AT1G73590), AUXILIN-LIKE1 (AT4G12780), AP1M2 (AT1G60780),
  ECHIDNA (AT1G09330), SEC5A (AT1G76850), SEC5B (AT1G21170), TUB2 (AT5G62690), and
  PP2AA3 (AT1G13320).'
date_created: 2026-08-04T06:48:41Z
date_published: 2026-07-20T00:00:00Z
date_updated: 2026-08-04T07:58:27Z
day: '20'
department:
- _id: JiFr
- _id: MaLo
- _id: GradSch
doi: 10.1111/nph.71454
external_id:
  pmid:
  - '42477503'
fulldoi: https://doi.org/10.1111/nph.71454
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/nph.71454
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: New Phytologist
publication_identifier:
  eissn:
  - 1469-8137
  issn:
  - 0028-646X
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: The role of clathrin in post‐Golgi secretion in plant cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22639'
abstract:
- lang: eng
  text: We present an abstract Dyson expansion for perturbations that are merely relatively
    form-bounded, and apply it to the polaron problem. For a large class of polaron-type
    models, including the Fröhlich and Nelson models, we prove that the vacuum expectation
    value of the heat semi-group is a completely monotone function of the square of
    the total momentum. Consequently, the ground-state energy is a concave function
    of the square of the momentum, a result recently proved for the Fröhlich model
    in [14] using a probabilistic approach via Wiener integrals.
acknowledgement: Open access funding provided by Institute of Science and Technology
  (IST Austria).
article_number: '87'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Davide
  full_name: Desio, Davide
  id: ea10a57b-23f6-11ef-9085-80d8596d52ef
  last_name: Desio
  orcid: 0000-0001-9840-3809
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Desio D, Seiringer R. Dyson expansion for form-bounded perturbations and applications
    to the polaron problem. <i>Letters in Mathematical Physics</i>. 2026;116(4). doi:<a
    href="https://doi.org/10.1007/s11005-026-02107-2">10.1007/s11005-026-02107-2</a>
  apa: Desio, D., &#38; Seiringer, R. (2026). Dyson expansion for form-bounded perturbations
    and applications to the polaron problem. <i>Letters in Mathematical Physics</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s11005-026-02107-2">https://doi.org/10.1007/s11005-026-02107-2</a>
  chicago: Desio, Davide, and Robert Seiringer. “Dyson Expansion for Form-Bounded
    Perturbations and Applications to the Polaron Problem.” <i>Letters in Mathematical
    Physics</i>. Springer Nature, 2026. <a href="https://doi.org/10.1007/s11005-026-02107-2">https://doi.org/10.1007/s11005-026-02107-2</a>.
  ieee: D. Desio and R. Seiringer, “Dyson expansion for form-bounded perturbations
    and applications to the polaron problem,” <i>Letters in Mathematical Physics</i>,
    vol. 116, no. 4. Springer Nature, 2026.
  ista: Desio D, Seiringer R. 2026. Dyson expansion for form-bounded perturbations
    and applications to the polaron problem. Letters in Mathematical Physics. 116(4),
    87.
  mla: Desio, Davide, and Robert Seiringer. “Dyson Expansion for Form-Bounded Perturbations
    and Applications to the Polaron Problem.” <i>Letters in Mathematical Physics</i>,
    vol. 116, no. 4, 87, Springer Nature, 2026, doi:<a href="https://doi.org/10.1007/s11005-026-02107-2">10.1007/s11005-026-02107-2</a>.
  short: D. Desio, R. Seiringer, Letters in Mathematical Physics 116 (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-03T13:21:14Z
date_published: 2026-07-17T00:00:00Z
date_updated: 2026-08-04T05:57:21Z
day: '17'
ddc:
- '510'
department:
- _id: RoSe
- _id: GradSch
doi: 10.1007/s11005-026-02107-2
external_id:
  arxiv:
  - '2512.13443'
file:
- access_level: open_access
  checksum: 1b90ff7da16b9604d6fe2c6281493456
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-04T05:55:58Z
  date_updated: 2026-08-04T05:55:58Z
  file_id: '22641'
  file_name: 2026_LettersMathPhysics_Desio.pdf
  file_size: 371840
  relation: main_file
  success: 1
file_date_updated: 2026-08-04T05:55:58Z
fulldoi: https://doi.org/10.1007/s11005-026-02107-2
has_accepted_license: '1'
intvolume: '       116'
issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Letters in Mathematical Physics
publication_identifier:
  issn:
  - 1573-0530
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Dyson expansion for form-bounded perturbations and applications to the polaron
  problem
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22644'
abstract:
- lang: eng
  text: "We analyze the average behavior of various arithmetic functions at the values
    of degree \U0001D451 binary forms ordered by height, with probability 1. This
    approach yields averaged versions of the Chowla conjecture and the Bateman–Horn
    conjecture for random binary forms. Furthermore, we show that the rational Hasse
    principle holds for almost all Châtelet varieties defined by a fixed norm form
    of degree \U0001D452 and by varying binary forms of fixed degree \U0001D451, provided
    \U0001D452 divides \U0001D451. This proves an average version of a conjecture
    of Colliot-Thélène."
acknowledgement: I am deeply grateful to my advisor Tim Browning for suggesting this
  problem and for the many valuable discussions that shaped this work. I would also
  like to thank Efthymios Sofos, Matteo Verzobio, and Shuntaro Yamagishi for discussions
  and insights that contributed to this paper. I am also very grateful to the anonymous
  referee for their careful reading and for the considerable effort they put into
  improving the manuscript.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Yijie
  full_name: Diao, Yijie
  id: 7b7eb4ca-eb2c-11ec-b98b-accec0b20c3b
  last_name: Diao
  orcid: 0000-0002-4989-5330
citation:
  ama: Diao Y. Liouville function, von Mangoldt function, and norm forms at random
    binary forms. <i>Glasgow Mathematical Journal</i>. 2026:1-34. doi:<a href="https://doi.org/10.1017/s0017089526101074">10.1017/s0017089526101074</a>
  apa: Diao, Y. (2026). Liouville function, von Mangoldt function, and norm forms
    at random binary forms. <i>Glasgow Mathematical Journal</i>. Cambridge University
    Press. <a href="https://doi.org/10.1017/s0017089526101074">https://doi.org/10.1017/s0017089526101074</a>
  chicago: Diao, Yijie. “Liouville Function, von Mangoldt Function, and Norm Forms
    at Random Binary Forms.” <i>Glasgow Mathematical Journal</i>. Cambridge University
    Press, 2026. <a href="https://doi.org/10.1017/s0017089526101074">https://doi.org/10.1017/s0017089526101074</a>.
  ieee: Y. Diao, “Liouville function, von Mangoldt function, and norm forms at random
    binary forms,” <i>Glasgow Mathematical Journal</i>. Cambridge University Press,
    pp. 1–34, 2026.
  ista: Diao Y. 2026. Liouville function, von Mangoldt function, and norm forms at
    random binary forms. Glasgow Mathematical Journal., 1–34.
  mla: Diao, Yijie. “Liouville Function, von Mangoldt Function, and Norm Forms at
    Random Binary Forms.” <i>Glasgow Mathematical Journal</i>, Cambridge University
    Press, 2026, pp. 1–34, doi:<a href="https://doi.org/10.1017/s0017089526101074">10.1017/s0017089526101074</a>.
  short: Y. Diao, Glasgow Mathematical Journal (2026) 1–34.
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-04T06:15:04Z
date_published: 2026-07-21T00:00:00Z
date_updated: 2026-08-04T06:28:01Z
day: '21'
ddc:
- '500'
department:
- _id: TiBr
- _id: GradSch
doi: 10.1017/s0017089526101074
external_id:
  arxiv:
  - '2506.18065'
fulldoi: https://doi.org/10.1017/s0017089526101074
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1017/S0017089526101074
mathsc:
- 11N32
- 11N37
- 11D57
- 11G35
month: '07'
oa: 1
oa_version: Published Version
page: 1-34
publication: Glasgow Mathematical Journal
publication_identifier:
  eissn:
  - 1469-509X
  issn:
  - 0017-0895
publication_status: epub_ahead
publisher: Cambridge University Press
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Liouville function, von Mangoldt function, and norm forms at random binary
  forms
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
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abstract:
- lang: eng
  text: "The appearance of simulated natural phenomena heavily depends on the way
    surfaces are textured. However, applying texture maps to dynamic deformable surfaces
    presents a significant challenge, due to ever-shifting differences in length scales
    involved. When these surfaces move and advect the texture along with them, their
    final appearance degrades as deformed regions dramatically distort their texture
    map. Modifications to the texture directly at the pixel level in response to the
    deformation may introduce ghosting artifacts and look unnatural. In the real world,
    the appearance of surface details on a deforming material changes through the
    interplay of physical processes such as rupturing, exposure of internal structure,
    or wrinkling. Motivated by these behaviors, in this work we explore how physical
    principles can guide the texturing methods based on the measure of surface deformation.\r\nWe
    present two novel wave-based procedural texturing algorithms which reproduce common
    physical properties like advection and self-similarity, enabling the plausible
    animation of deforming objects with extreme texture map distortions. Our algorithms
    are fully procedural, require no actual physics simulation, and store no state
    or history of deformation besides the input UV map, making them highly parallelizable
    on the GPU and efficient enough for real-time applications. We show the versatility
    of the method by animating physical phenomena with extreme deformations such as
    flowing lava, stretching putty and outpouring sludge."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank the anonymous reviewers for their helpful comments, the
  members of the Visual Computing Group at ISTA for their feedback. We also thank
  Jonathan Gagnon for their help with running the Lapped Textures codes and SideFX
  for the Houdini Education software licenses.\r\nImages in Fig. 2 by Kisoulou and
  Vultured on Unsplash, Michal Jarmoluk and Public Domain Pictures from Pixabay and
  Hawai‘i Volcanoes NPS on flickr. This research was supported by the Scientific Service
  Units (SSU) of ISTA through resources provided by Scientific Computing and was funded
  in part by the European Union (ERC-2021-COG 101045083 CoDiNA)."
article_number: '154'
article_processing_charge: Yes
article_type: original
author:
- first_name: Aleksei
  full_name: Kalinov, Aleksei
  id: 44b7120e-eb97-11eb-a6c2-e1557aa81d02
  last_name: Kalinov
  orcid: 0000-0003-2189-3904
- first_name: Mickaël
  full_name: Ly, Mickaël
  id: 6340d7f0-b48d-11eb-b10d-b7487e71d9f1
  last_name: Ly
- first_name: Christian
  full_name: Hafner, Christian
  id: 400429CC-F248-11E8-B48F-1D18A9856A87
  last_name: Hafner
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
citation:
  ama: Kalinov A, Ly M, Hafner C, Wojtan C. Physics-inspired procedural texturing
    of extremely deformable surfaces. <i>ACM Transactions on Graphics</i>. 2026;45(4).
    doi:<a href="https://doi.org/10.1145/3811353">10.1145/3811353</a>
  apa: 'Kalinov, A., Ly, M., Hafner, C., &#38; Wojtan, C. (2026). Physics-inspired
    procedural texturing of extremely deformable surfaces. <i>ACM Transactions on
    Graphics</i>. Los Angeles, CA, United States: Association for Computing Machinery.
    <a href="https://doi.org/10.1145/3811353">https://doi.org/10.1145/3811353</a>'
  chicago: Kalinov, Aleksei, Mickaël Ly, Christian Hafner, and Chris Wojtan. “Physics-Inspired
    Procedural Texturing of Extremely Deformable Surfaces.” <i>ACM Transactions on
    Graphics</i>. Association for Computing Machinery, 2026. <a href="https://doi.org/10.1145/3811353">https://doi.org/10.1145/3811353</a>.
  ieee: A. Kalinov, M. Ly, C. Hafner, and C. Wojtan, “Physics-inspired procedural
    texturing of extremely deformable surfaces,” <i>ACM Transactions on Graphics</i>,
    vol. 45, no. 4. Association for Computing Machinery, 2026.
  ista: Kalinov A, Ly M, Hafner C, Wojtan C. 2026. Physics-inspired procedural texturing
    of extremely deformable surfaces. ACM Transactions on Graphics. 45(4), 154.
  mla: Kalinov, Aleksei, et al. “Physics-Inspired Procedural Texturing of Extremely
    Deformable Surfaces.” <i>ACM Transactions on Graphics</i>, vol. 45, no. 4, 154,
    Association for Computing Machinery, 2026, doi:<a href="https://doi.org/10.1145/3811353">10.1145/3811353</a>.
  short: A. Kalinov, M. Ly, C. Hafner, C. Wojtan, ACM Transactions on Graphics 45
    (2026).
conference:
  end_date: 2026-07-23
  location: Los Angeles, CA, United States
  name: 'SIGGRAPH: International Conference and Exhibition on Computer Graphics and
    Interactive Techniques'
  start_date: 2026-07-19
corr_author: '1'
das_tickbox: '0'
date_created: 2026-05-29T13:25:16Z
date_published: 2026-07-01T00:00:00Z
date_updated: 2026-08-04T09:07:44Z
day: '01'
ddc:
- '006'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1145/3811353
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  date_updated: 2026-05-29T13:19:33Z
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file_date_updated: 2026-05-29T13:19:37Z
fulldoi: https://doi.org/10.1145/3811353
has_accepted_license: '1'
intvolume: '        45'
issue: '4'
keyword:
- Procedural animation
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: ACM Transactions on Graphics
publication_identifier:
  issn:
  - 0730-0301
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/infinite-deformation-and-shape-computation/
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Physics-inspired procedural texturing of extremely deformable surfaces
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 45
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
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_id: '22295'
abstract:
- lang: eng
  text: 'Despite the functional diversity of over 100 causal genes1,2,3, phenotypic
    convergence across models may reveal common neurobiological processes in autism
    spectrum disorder (ASD). Here we profiled 251 samples from 11 monogenic mouse
    models of ASD using single-nucleus multi-omic sequencing across three developmental
    stages, both sexes and two brain regions. Despite genetic heterogeneity, ASD-linked
    mutations converged on perturbations of the radial glial cell lineage. These alterations
    reflect a transient developmental delay rather than lasting lineage misspecification
    and resolve by postnatal stages. Molecularly, the largest transcriptional differences
    emerged in neurons at early postnatal stages. These changes included downregulation
    of synaptic and ion channel-related genes, consistent with homeostatic adaptation
    or delayed maturation. Network analysis showed molecular convergence across models
    within each developmental stage, suggesting that diverse mutations linked to ASD
    impinge on common, stage-specific processes. Convergence becomes less pronounced
    by postnatal day 14, highlighting the dynamic nature of ASD-associated changes.
    Cross-genotype heterogeneity is superimposed on stage-specific effects. Electrophysiology
    corroborated this pattern: mutants generally showed altered neuronal excitability
    and synaptic properties with model-specific nuances. Our study also highlighted
    sex-specific gene expression alterations, with female mice often displaying larger
    effect sizes than male mice. Together, our findings provide a comprehensive view
    of developmental cellular and molecular dynamics across models of ASD.'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: We thank F. Freeman, V. Voronin and M. Ladron de Guevara for technical
  assistance; A. Stichelberger and S. Liegenfeld for the management of our animal
  colony; M. Schunn, C. Gold and the Preclinical Facility team for technical assistance;
  C. Jansen and the Scientific Computing Facility for bioinformatics support and technical
  assistance; the Biomedical Sequencing Facility at CeMM for assistance with next-generation
  sequencing; and J. Lin and T. Krausgruber in the laboratory of C. Bock for support
  with flow cytometry; J. Kirchner for illustrating the multi-omics approach depicted
  in Fig. 1; and all members of the laboratory of G.N. for their support and discussions.
  This study was supported by the Scientific Service Units of ISTA through resources
  provided by the Imaging & Optics Facility and the Laboratory Support Facility. Bulk
  RNA-seq was performed by the Next Generation Sequencing Facility at Vienna BioCenter
  Core Facilities, member of the Vienna BioCenter. This work was supported by a European
  Research Council Consolidator Grant (PR1028ERC02), by SFARI (PR1028SIM02) and by
  the Austrian Science Fund (PE1028W1232 and PR1028FG1803) to G.N. Open access funding
  provided by Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Lena A
  full_name: Schwarz, Lena A
  id: 29A8453C-F248-11E8-B48F-1D18A9856A87
  last_name: Schwarz
- first_name: Christoph
  full_name: Dotter, Christoph
  id: 4C66542E-F248-11E8-B48F-1D18A9856A87
  last_name: Dotter
  orcid: 0000-0002-9033-9096
- first_name: Sergey
  full_name: Isaev, Sergey
  last_name: Isaev
- first_name: Michela
  full_name: Lisi, Michela
  id: 39383c1b-d3eb-11ef-8d6c-c8cdf4e10c8c
  last_name: Lisi
- first_name: Daniel
  full_name: Malzl, Daniel
  last_name: Malzl
- first_name: Christoph
  full_name: Büschl, Christoph
  id: 2a8c054c-0913-11ee-9159-f8ef515809ed
  last_name: Büschl
- first_name: Sabrina
  full_name: Ladstätter, Sabrina
  last_name: Ladstätter
- first_name: Bárbara
  full_name: Oliveira, Bárbara
  id: 3B03AA1A-F248-11E8-B48F-1D18A9856A87
  last_name: Oliveira
- first_name: Matteo
  full_name: Barel, Matteo
  id: 8959927b-2236-11ed-bd6e-ea83d94ade0e
  last_name: Barel
- first_name: Bernadette
  full_name: Basilico, Bernadette
  id: 36035796-5ACA-11E9-A75E-7AF2E5697425
  last_name: Basilico
  orcid: 0000-0003-1843-3173
- first_name: Chaitanya
  full_name: Chintaluri, Chaitanya
  id: BA06AFEE-A4BA-11EA-AE5C-14673DDC885E
  last_name: Chintaluri
  orcid: 0000-0003-4252-1608
- first_name: Sarah
  full_name: Gorkiewicz, Sarah
  id: f141a35d-15a9-11ec-9fb2-fef6becc7b6f
  last_name: Gorkiewicz
- first_name: Mohammad
  full_name: Goudarzi, Mohammad
  id: 3384113A-F248-11E8-B48F-1D18A9856A87
  last_name: Goudarzi
- first_name: Tereza
  full_name: Belinova, Tereza
  id: 0bf89b6a-d28b-11eb-8bd6-f43768e4d368
  last_name: Belinova
- first_name: Stephan
  full_name: Reichl, Stephan
  last_name: Reichl
- first_name: Gintarė
  full_name: Sendžikaitė, Gintarė
  id: dd6d52f2-c50d-11eb-9548-bcf0ff82b344
  last_name: Sendžikaitė
- first_name: Satish
  full_name: Arcot Jayaram, Satish
  id: b0bbee33-09f7-11eb-909c-8b358058d28a
  last_name: Arcot Jayaram
  orcid: 0000-0002-2479-2669
- first_name: Peter
  full_name: Koppensteiner, Peter
  id: 3B8B25A8-F248-11E8-B48F-1D18A9856A87
  last_name: Koppensteiner
  orcid: 0000-0002-3509-1948
- first_name: Christoph M
  full_name: Sommer, Christoph M
  id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
  last_name: Sommer
  orcid: 0000-0003-1216-9105
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
- first_name: Jörg
  full_name: Menche, Jörg
  last_name: Menche
- first_name: Igor
  full_name: Adameyko, Igor
  last_name: Adameyko
- first_name: Peter Vasili
  full_name: Kharchenko, Peter Vasili
  id: 0095641e-7eb7-11f1-8665-aec51a2ab5e0
  last_name: Kharchenko
- first_name: Christoph
  full_name: Bock, Christoph
  last_name: Bock
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
citation:
  ama: Schwarz LA, Dotter C, Isaev S, et al. Cortical development dynamics across
    autism spectrum disorder mouse models. <i>Nature</i>. 2026. doi:<a href="https://doi.org/10.1038/s41586-026-10679-1">10.1038/s41586-026-10679-1</a>
  apa: Schwarz, L. A., Dotter, C., Isaev, S., Lisi, M., Malzl, D., Büschl, C., … Novarino,
    G. (2026). Cortical development dynamics across autism spectrum disorder mouse
    models. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/s41586-026-10679-1">https://doi.org/10.1038/s41586-026-10679-1</a>
  chicago: Schwarz, Lena A, Christoph Dotter, Sergey Isaev, Michela Lisi, Daniel Malzl,
    Christoph Büschl, Sabrina Ladstätter, et al. “Cortical Development Dynamics across
    Autism Spectrum Disorder Mouse Models.” <i>Nature</i>. Springer Nature, 2026.
    <a href="https://doi.org/10.1038/s41586-026-10679-1">https://doi.org/10.1038/s41586-026-10679-1</a>.
  ieee: L. A. Schwarz <i>et al.</i>, “Cortical development dynamics across autism
    spectrum disorder mouse models,” <i>Nature</i>. Springer Nature, 2026.
  ista: Schwarz LA, Dotter C, Isaev S, Lisi M, Malzl D, Büschl C, Ladstätter S, Oliveira
    B, Barel M, Basilico B, Chintaluri C, Gorkiewicz S, Goudarzi M, Belinova T, Reichl
    S, Sendžikaitė G, Arcot Jayaram S, Koppensteiner P, Sommer CM, Vogels TP, Menche
    J, Adameyko I, Kharchenko PV, Bock C, Novarino G. 2026. Cortical development dynamics
    across autism spectrum disorder mouse models. Nature.
  mla: Schwarz, Lena A., et al. “Cortical Development Dynamics across Autism Spectrum
    Disorder Mouse Models.” <i>Nature</i>, Springer Nature, 2026, doi:<a href="https://doi.org/10.1038/s41586-026-10679-1">10.1038/s41586-026-10679-1</a>.
  short: L.A. Schwarz, C. Dotter, S. Isaev, M. Lisi, D. Malzl, C. Büschl, S. Ladstätter,
    B. Oliveira, M. Barel, B. Basilico, C. Chintaluri, S. Gorkiewicz, M. Goudarzi,
    T. Belinova, S. Reichl, G. Sendžikaitė, S. Arcot Jayaram, P. Koppensteiner, C.M.
    Sommer, T.P. Vogels, J. Menche, I. Adameyko, P.V. Kharchenko, C. Bock, G. Novarino,
    Nature (2026).
corr_author: '1'
dataavailabilitystatement: Single-nucleus multiomics data are available from the Gene
  Expression Omnibus (GSE328363). The mm10 reference genome was used for the alignment
  (refdata-cellranger-arc-mm10-2020-A-2.0.0, obtained from https://cf.10xgenomics.com/supp/cell-arc/refdata-cellranger-arc-mm10-2020-A-2.0.0.tar.gz).
  Single-cell data can be accessed and visualized through a CELLxGENE database (https://adameykolab.hifo.meduniwien.ac.at/cellxgene_public/filecrawl/.2026_Nature_Schwarz).
  Source data are provided with this paper. Scripts and analyses that support the
  main findings of this study are accessible in a GitHub repository (https://git.ista.ac.at/research-sofware/mouseome).
date_created: 2026-07-13T09:47:21Z
date_published: 2026-06-17T00:00:00Z
date_updated: 2026-08-04T09:29:55Z
day: '17'
ddc:
- '570'
department:
- _id: AnKi
- _id: GaNo
- _id: TiVo
- _id: ScienComp
- _id: GradSch
- _id: Bio
- _id: PreCl
doi: 10.1038/s41586-026-10679-1
external_id:
  pmid:
  - '42310454'
fulldoi: https://doi.org/10.1038/s41586-026-10679-1
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41586-026-10679-1
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 34ba8964-11ca-11ed-8bc3-e15864e7e9a6
  grant_number: '101044865'
  name: Toward an understanding of the brain interstitial system and the extracellular
    proteome in health and autism spectrum disorders
- _id: 9B91375C-BA93-11EA-9121-9846C619BF3A
  grant_number: '707964'
  name: Critical windows and reversibility of ASD associated with mutations in chromatin
    remodelers
- _id: 2548AE96-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: W1232
  name: Molecular Drug Targets
- _id: ebb38b5d-77a9-11ec-83b8-a42e08120a88
  grant_number: FG1803 49015
  name: Neurobiology of anxiety in autism spectrum disorders
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/patterns-in-genetic-chaos/
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Cortical development dynamics across autism spectrum disorder mouse models
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22268'
abstract:
- lang: eng
  text: AlphaFold3 predicts highly accurate protein structures from sequence but tends
    to collapse to a single dominant conformation, even when the underlying structure
    is inherently heterogeneous. Moreover, its predictions are oblivious to experimental
    conditions that can alter local sequence conformation. In this work, we show that
    AlphaFold3 can be guided to match data obtained by nuclear magnetic resonance
    (NMR) spectroscopy, X-ray crystallography and cryogenic electron microscopy (cryo-EM)
    experiments and combinations thereof. Our approach can also incorporate data that
    explicitly report on dynamics, such as site-resolved order parameters. We demonstrate
    that this methodology generates compact structural ensembles whose ensemble-averaged
    observables agree with experiment, with fewer distance restraint violations than
    traditionally resolved NMR structures and with unmodeled alternate conformations
    uncovered in electron density. This methodology paves the way for experimentally
    aware predictive models that generate structural ensembles consistent with the
    measurements, potentially over multiple modalities, and that can be further refined
    toward thermodynamically grounded ensembles by incorporating energetics.
acknowledgement: A. Marx acknowledges the financial support of the Helmsley Fellowships
  Program for Sustainability and Health. A.M.B. and P.S. are supported by the Institute
  of Science and Technology Austria Internal Project Call grant Generative Protein
  NMR. S.V. was supported in part by funding from the Eric and Wendy Schmidt Center
  at the Broad Institute of MIT and Harvard. Open access funding provided by Institute
  of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Sai A
  full_name: Maddipatla, Sai A
  id: e957f5e5-91c9-11f0-a95f-e090f66ecb4d
  last_name: Maddipatla
- first_name: Nadav E
  full_name: Sellam, Nadav E
  id: ef280fe0-91c9-11f0-a95f-8dea3f5bc513
  last_name: Sellam
- first_name: Meital I
  full_name: Bojan, Meital I
  id: 11d88cf5-91ca-11f0-a95f-edf9f08f47b7
  last_name: Bojan
- first_name: Vova
  full_name: Masalitin, Vova
  id: ff7958eb-91c9-11f0-a95f-f3bf65828cf6
  last_name: Masalitin
- first_name: Sanketh
  full_name: Vedula, Sanketh
  last_name: Vedula
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Ailie
  full_name: Marx, Ailie
  last_name: Marx
- first_name: Alexander
  full_name: Bronstein, Alexander
  id: 58f3726e-7cba-11ef-ad8b-e6e8cb3904e6
  last_name: Bronstein
  orcid: 0000-0001-9699-8730
citation:
  ama: Maddipatla SA, Sellam NE, Bojan MI, et al. Experiment-guided AlphaFold3 resolves
    measurement-consistent protein ensembles. <i>Nature Biotechnology</i>. 2026. doi:<a
    href="https://doi.org/10.1038/s41587-026-03166-5">10.1038/s41587-026-03166-5</a>
  apa: Maddipatla, S. A., Sellam, N. E., Bojan, M. I., Masalitin, V., Vedula, S.,
    Schanda, P., … Bronstein, A. M. (2026). Experiment-guided AlphaFold3 resolves
    measurement-consistent protein ensembles. <i>Nature Biotechnology</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41587-026-03166-5">https://doi.org/10.1038/s41587-026-03166-5</a>
  chicago: Maddipatla, Sai A, Nadav E Sellam, Meital I Bojan, Vova Masalitin, Sanketh
    Vedula, Paul Schanda, Ailie Marx, and Alex M. Bronstein. “Experiment-Guided AlphaFold3
    Resolves Measurement-Consistent Protein Ensembles.” <i>Nature Biotechnology</i>.
    Springer Nature, 2026. <a href="https://doi.org/10.1038/s41587-026-03166-5">https://doi.org/10.1038/s41587-026-03166-5</a>.
  ieee: S. A. Maddipatla <i>et al.</i>, “Experiment-guided AlphaFold3 resolves measurement-consistent
    protein ensembles,” <i>Nature Biotechnology</i>. Springer Nature, 2026.
  ista: Maddipatla SA, Sellam NE, Bojan MI, Masalitin V, Vedula S, Schanda P, Marx
    A, Bronstein AM. 2026. Experiment-guided AlphaFold3 resolves measurement-consistent
    protein ensembles. Nature Biotechnology.
  mla: Maddipatla, Sai A., et al. “Experiment-Guided AlphaFold3 Resolves Measurement-Consistent
    Protein Ensembles.” <i>Nature Biotechnology</i>, Springer Nature, 2026, doi:<a
    href="https://doi.org/10.1038/s41587-026-03166-5">10.1038/s41587-026-03166-5</a>.
  short: S.A. Maddipatla, N.E. Sellam, M.I. Bojan, V. Masalitin, S. Vedula, P. Schanda,
    A. Marx, A.M. Bronstein, Nature Biotechnology (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: All structures and metrics reported in this paper are openly
  available on Harvard Dataverse - https://doi.org/10.7910/DVN/PLYUHN. All code is
  openly available on GitHub (https://github.com/sai-advaith/guided_alphafold); the
  version used for this paper (version 0.9.1) is permanently archived on Zenodo https://doi.org/10.5281/zenodo.17307005
date_created: 2026-07-12T22:02:19Z
date_published: 2026-06-29T00:00:00Z
date_updated: 2026-08-04T09:25:18Z
day: '29'
ddc:
- '570'
department:
- _id: PaSc
- _id: AlBr
- _id: GradSch
doi: 10.1038/s41587-026-03166-5
external_id:
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  - '42374114'
fulldoi: https://doi.org/10.1038/s41587-026-03166-5
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41587-026-03166-5
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Biotechnology
publication_identifier:
  eissn:
  - 1546-1696
  issn:
  - 1087-0156
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/toward-experiment-guided-alphafold/
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
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abstract:
- lang: eng
  text: "Characterizing protein dynamics at the atomic level is essential for our
    understanding of biological mechanisms. Whether it is to facilitate metabolite
    transport, catalyze reactions, transmit signals, or regulate metabolism – proteins
    are constantly in motion and sample multiple conformational states to fulfill
    their function. Nuclear magnetic resonance (NMR) spectroscopy is particularly
    well suited to elucidate the dynamics of biomolecules on their complex free-energy
    landscape. In particular, solid-state magic-angle spinning (MAS) NMR enables the
    study of large molecular assemblies, protein crystals, or insoluble proteins at
    atomic resolution without an inherent molecular size limitation. MAS NMR experiments
    to probe protein dynamics are extremely versatile and sensitive to motional timescales
    from picoseconds to seconds. Over the past decades, technological advances, developments
    in experimental design, and new isotope-labeling approaches have further expanded
    the possibilities of this technique and significantly improved the accuracy of
    the determined motional parameters.\r\nFunctionally important sites of proteins
    often contain aromatic residues. Their side-chain motions have therefore long
    served as valuable indicators of mechanistically relevant dynamics in NMR studies.
    In this thesis, site-specifically labeled aromatic residues act as sensitive reporters
    for MAS NMR studies of protein dynamics. The first part addresses how different
    environments impact side-chain motion by probing ring flips of phenylalanines
    and tyrosines in crystalline proteins and amyloid fibrils. It provides important
    insights for the analysis of dynamics obtained in non-native protein environments
    and emphasizes the complex factors that determine the timescale of internal dynamics.
    In the second part, the focus shifts towards methodological questions regarding
    the investigation of protein dynamics by 19F MAS NMR. The fluorine nucleus exhibits
    promising characteristics for NMR studies but also presents significant challenges,
    which is why the full methodological potential of 19F MAS NMR has not been fully
    realized yet. This work demonstrates that paramagnetic doping can considerably
    reduce the measurement time and improve the sensitivity of fluorinated samples.
    Finally, 19F MAS NMR is evaluated as a tool for studying protein side-chain dynamics
    on the example of tryptophans. The results illustrate the challenges in analyzing
    such experiments and lay the foundation for further development of 19F MAS NMR
    relaxation studies.\r\nTaken together, this thesis highlights the potential of
    combining specific isotope labeling, MAS NMR, and complementary methods such as
    crystallography and computational simulations to elucidate internal protein dynamics.
    The further development of such integrative approaches will be crucial to improving
    our understanding of complex mechanisms and protein function.\r\n"
acknowledged_ssus:
- _id: LifeSc
- _id: NMR
acknowledgement: "During the work on this thesis, I was the recipient of a DOC Fellowship
  of the Austrian\r\nAcademy of Sciences at the Institute of Science and Technology
  Austria (grant no. PR10660EAW01)."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Lea Marie
  full_name: Becker, Lea Marie
  id: 36336939-eb97-11eb-a6c2-c83f1214ca79
  last_name: Becker
  orcid: 0000-0002-6401-5151
citation:
  ama: Becker LM. Exploring protein dynamics using specific labeling approaches for
    solid-state MAS NMR. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22334">10.15479/AT-ISTA-22334</a>
  apa: Becker, L. M. (2026). <i>Exploring protein dynamics using specific labeling
    approaches for solid-state MAS NMR</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-22334">https://doi.org/10.15479/AT-ISTA-22334</a>
  chicago: Becker, Lea Marie. “Exploring Protein Dynamics Using Specific Labeling
    Approaches for Solid-State MAS NMR.” Institute of Science and Technology Austria,
    2026. <a href="https://doi.org/10.15479/AT-ISTA-22334">https://doi.org/10.15479/AT-ISTA-22334</a>.
  ieee: L. M. Becker, “Exploring protein dynamics using specific labeling approaches
    for solid-state MAS NMR,” Institute of Science and Technology Austria, 2026.
  ista: Becker LM. 2026. Exploring protein dynamics using specific labeling approaches
    for solid-state MAS NMR. Institute of Science and Technology Austria.
  mla: Becker, Lea Marie. <i>Exploring Protein Dynamics Using Specific Labeling Approaches
    for Solid-State MAS NMR</i>. Institute of Science and Technology Austria, 2026,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-22334">10.15479/AT-ISTA-22334</a>.
  short: L.M. Becker, Exploring Protein Dynamics Using Specific Labeling Approaches
    for Solid-State MAS NMR, Institute of Science and Technology Austria, 2026.
corr_author: '1'
das_tickbox: '1'
date_created: 2026-07-14T08:08:51Z
date_published: 2026-07-13T00:00:00Z
date_updated: 2026-08-04T09:32:45Z
day: '13'
ddc:
- '572'
degree_awarded: PhD
department:
- _id: GradSch
- _id: PaSc
doi: 10.15479/AT-ISTA-22334
doi_confirm: '1'
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fulldoi: https://doi.org/10.15479/AT-ISTA-22334
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '07'
oa: 1
oa_version: Published Version
page: '205'
project:
- _id: 7be609c4-9f16-11ee-852c-85015ce2b9b0
  grant_number: '26777'
  name: Exploring protein dynamics by solid-state MAS NMR through specific labeling
    approaches
publication_identifier:
  isbn:
  - 978-3-99078-084-8
  issn:
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publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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status: public
supervisor:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
title: Exploring protein dynamics using specific labeling approaches for solid-state
  MAS NMR
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    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
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...
