[{"scopus_import":"1","_id":"13129","type":"journal_article","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).","intvolume":" 24","oa_version":"Published Version","article_type":"original","date_updated":"2025-01-09T07:37:50Z","department":[{"_id":"JuFi"}],"publisher":"Springer Nature","date_published":"2024-08-01T00:00:00Z","language":[{"iso":"eng"}],"month":"08","file_date_updated":"2025-01-09T07:36:57Z","oa":1,"isi":1,"day":"01","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"OA_type":"hybrid","citation":{"mla":"Clozeau, Nicolas, et al. “Bias in the Representative Volume Element Method: Periodize the Ensemble Instead of Its Realizations.” Foundations of Computational Mathematics, vol. 24, Springer Nature, 2024, pp. 1305–87, doi:10.1007/s10208-023-09613-y.","chicago":"Clozeau, Nicolas, Marc Josien, Felix Otto, and Qiang Xu. “Bias in the Representative Volume Element Method: Periodize the Ensemble Instead of Its Realizations.” Foundations of Computational Mathematics. Springer Nature, 2024. https://doi.org/10.1007/s10208-023-09613-y.","apa":"Clozeau, N., Josien, M., Otto, F., & Xu, Q. (2024). Bias in the representative volume element method: Periodize the ensemble instead of its realizations. Foundations of Computational Mathematics. Springer Nature. https://doi.org/10.1007/s10208-023-09613-y","ista":"Clozeau N, Josien M, Otto F, Xu Q. 2024. Bias in the representative volume element method: Periodize the ensemble instead of its realizations. Foundations of Computational Mathematics. 24, 1305–1387.","ama":"Clozeau N, Josien M, Otto F, Xu Q. Bias in the representative volume element method: Periodize the ensemble instead of its realizations. Foundations of Computational Mathematics. 2024;24:1305-1387. doi:10.1007/s10208-023-09613-y","short":"N. Clozeau, M. Josien, F. Otto, Q. Xu, Foundations of Computational Mathematics 24 (2024) 1305–1387.","ieee":"N. Clozeau, M. Josien, F. Otto, and Q. Xu, “Bias in the representative volume element method: Periodize the ensemble instead of its realizations,” Foundations of Computational Mathematics, vol. 24. Springer Nature, pp. 1305–1387, 2024."},"OA_place":"publisher","volume":24,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Nicolas","last_name":"Clozeau","id":"fea1b376-906f-11eb-847d-b2c0cf46455b","full_name":"Clozeau, Nicolas"},{"full_name":"Josien, Marc","first_name":"Marc","last_name":"Josien"},{"first_name":"Felix","last_name":"Otto","full_name":"Otto, Felix"},{"full_name":"Xu, Qiang","last_name":"Xu","first_name":"Qiang"}],"title":"Bias in the representative volume element method: Periodize the ensemble instead of its realizations","external_id":{"isi":["000999623100001"]},"publication_status":"published","abstract":[{"text":"We study the representative volume element (RVE) method, which is a method to approximately infer the effective behavior ahom of a stationary random medium. The latter is described by a coefficient field a(x) generated from a given ensemble ⟨⋅⟩ and the corresponding linear elliptic operator −∇⋅a∇. In line with the theory of homogenization, the method proceeds by computing d=3 correctors (d denoting the space dimension). To be numerically tractable, this computation has to be done on a finite domain: the so-called representative volume element, i.e., a large box with, say, periodic boundary conditions. The main message of this article is: Periodize the ensemble instead of its realizations. By this, we mean that it is better to sample from a suitably periodized ensemble than to periodically extend the restriction of a realization a(x) from the whole-space ensemble ⟨⋅⟩. We make this point by investigating the bias (or systematic error), i.e., the difference between ahom and the expected value of the RVE method, in terms of its scaling w.r.t. the lateral size L of the box. In case of periodizing a(x), we heuristically argue that this error is generically O(L−1). In case of a suitable periodization of ⟨⋅⟩\r\n, we rigorously show that it is O(L−d). In fact, we give a characterization of the leading-order error term for both strategies and argue that even in the isotropic case it is generically non-degenerate. We carry out the rigorous analysis in the convenient setting of ensembles ⟨⋅⟩\r\n of Gaussian type, which allow for a straightforward periodization, passing via the (integrable) covariance function. This setting has also the advantage of making the Price theorem and the Malliavin calculus available for optimal stochastic estimates of correctors. We actually need control of second-order correctors to capture the leading-order error term. This is due to inversion symmetry when applying the two-scale expansion to the Green function. As a bonus, we present a stream-lined strategy to estimate the error in a higher-order two-scale expansion of the Green function.","lang":"eng"}],"article_processing_charge":"Yes (via OA deal)","page":"1305-1387","publication":"Foundations of Computational Mathematics","publication_identifier":{"eissn":["1615-3383"],"issn":["1615-3375"]},"doi":"10.1007/s10208-023-09613-y","date_created":"2023-06-11T22:00:40Z","year":"2024","ddc":["510"],"has_accepted_license":"1","quality_controlled":"1","file":[{"success":1,"creator":"dernst","date_created":"2025-01-09T07:36:57Z","content_type":"application/pdf","file_name":"2024_FoundCompMath_Clozeau.pdf","access_level":"open_access","relation":"main_file","checksum":"ec0582e2b55e2703a7da2686ae0d682e","date_updated":"2025-01-09T07:36:57Z","file_size":1454406,"file_id":"18782"}],"corr_author":"1"},{"publication":"Annales Henri Poincare","doi":"10.1007/s00023-023-01345-7","publication_identifier":{"issn":["1424-0637"]},"year":"2024","date_created":"2023-07-23T22:01:15Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2108.05785"}],"quality_controlled":"1","corr_author":"1","volume":25,"author":[{"id":"D8F41E38-9E66-11E9-A9E2-65C2E5697425","full_name":"Zhang, Haonan","last_name":"Zhang","first_name":"Haonan"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Some convexity and monotonicity results of trace functionals","abstract":[{"text":"In this paper, we prove the convexity of trace functionals (A,B,C)↦Tr|BpACq|s,\r\nfor parameters (p, q, s) that are best possible, where B and C are any n-by-n positive-definite matrices, and A is any n-by-n matrix. We also obtain the monotonicity versions of trace functionals of this type. As applications, we extend some results in Carlen et al. (Linear Algebra Appl 490:174–185, 2016), Hiai and Petz (Publ Res Inst Math Sci 48(3):525-542, 2012) and resolve a conjecture in Al-Rashed and Zegarliński (Infin Dimens Anal Quantum Probab Relat Top 17(4):1450029, 2014) in the matrix setting. Other conjectures in Al-Rashed and Zegarliński (Infin Dimens Anal Quantum Probab Relat Top 17(4):1450029, 2014) will also be discussed. We also show that some related trace functionals are not concave in general. Such concavity results were expected to hold in different problems.","lang":"eng"}],"external_id":{"isi":["001025709100001"],"arxiv":["2108.05785"]},"publication_status":"published","page":"2087-2106","article_processing_charge":"No","status":"public","day":"01","ec_funded":1,"project":[{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"},{"name":"Curvature-dimension in noncommutative analysis","grant_number":"M03337","_id":"eb958bca-77a9-11ec-83b8-c565cb50d8d6"}],"citation":{"mla":"Zhang, Haonan. “Some Convexity and Monotonicity Results of Trace Functionals.” Annales Henri Poincare, vol. 25, Springer Nature, 2024, pp. 2087–106, doi:10.1007/s00023-023-01345-7.","apa":"Zhang, H. (2024). Some convexity and monotonicity results of trace functionals. Annales Henri Poincare. Springer Nature. https://doi.org/10.1007/s00023-023-01345-7","chicago":"Zhang, Haonan. “Some Convexity and Monotonicity Results of Trace Functionals.” Annales Henri Poincare. Springer Nature, 2024. https://doi.org/10.1007/s00023-023-01345-7.","ista":"Zhang H. 2024. Some convexity and monotonicity results of trace functionals. Annales Henri Poincare. 25, 2087–2106.","ama":"Zhang H. Some convexity and monotonicity results of trace functionals. Annales Henri Poincare. 2024;25:2087-2106. doi:10.1007/s00023-023-01345-7","short":"H. Zhang, Annales Henri Poincare 25 (2024) 2087–2106.","ieee":"H. Zhang, “Some convexity and monotonicity results of trace functionals,” Annales Henri Poincare, vol. 25. Springer Nature, pp. 2087–2106, 2024."},"_id":"13271","scopus_import":"1","acknowledgement":"I am grateful to Boguslaw Zegarliński for asking me the questions in [3] and for helpful communication. I also want to thank Paata Ivanisvili for drawing [25] to my attention and for useful correspondence. Many thanks to the anonymous referee for the valuable comments and for pointing out some errors in an earlier version of the paper. This work is partially supported by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 754411 and the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337.","type":"journal_article","article_type":"original","oa_version":"Preprint","intvolume":" 25","publisher":"Springer Nature","department":[{"_id":"JaMa"}],"arxiv":1,"date_updated":"2025-04-14T07:43:55Z","language":[{"iso":"eng"}],"month":"04","date_published":"2024-04-01T00:00:00Z","oa":1,"isi":1},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Volberg, Alexander","last_name":"Volberg","first_name":"Alexander"},{"full_name":"Zhang, Haonan","id":"D8F41E38-9E66-11E9-A9E2-65C2E5697425","last_name":"Zhang","first_name":"Haonan"}],"volume":389,"pmid":1,"page":"1657-1676","article_processing_charge":"Yes (in subscription journal)","abstract":[{"text":"Bohnenblust–Hille inequalities for Boolean cubes have been proven with dimension-free constants that grow subexponentially in the degree (Defant et al. in Math Ann 374(1):653–680, 2019). Such inequalities have found great applications in learning low-degree Boolean functions (Eskenazis and Ivanisvili in Proceedings of the 54th annual ACM SIGACT symposium on theory of computing, pp 203–207, 2022). Motivated by learning quantum observables, a qubit analogue of Bohnenblust–Hille inequality for Boolean cubes was recently conjectured in Rouzé et al. (Quantum Talagrand, KKL and Friedgut’s theorems and the learnability of quantum Boolean functions, 2022. arXiv preprint arXiv:2209.07279). The conjecture was resolved in Huang et al. (Learning to predict arbitrary quantum processes, 2022. arXiv preprint arXiv:2210.14894). In this paper, we give a new proof of these Bohnenblust–Hille inequalities for qubit system with constants that are dimension-free and of exponential growth in the degree. As a consequence, we obtain a junta theorem for low-degree polynomials. Using similar ideas, we also study learning problems of low degree quantum observables and Bohr’s radius phenomenon on quantum Boolean cubes.","lang":"eng"}],"external_id":{"pmid":["38751410"],"arxiv":["2210.14468"],"isi":["001035665500001"]},"publication_status":"published","title":"Noncommutative Bohnenblust–Hille inequalities","year":"2024","date_created":"2023-07-30T22:01:03Z","publication_identifier":{"issn":["0025-5831"],"eissn":["1432-1807"]},"doi":"10.1007/s00208-023-02680-0","publication":"Mathematische Annalen","corr_author":"1","quality_controlled":"1","file":[{"creator":"dernst","success":1,"date_created":"2024-07-22T09:38:15Z","file_name":"2024_MathAnnalen_Volberg.pdf","content_type":"application/pdf","relation":"main_file","checksum":"56e67756e4c6c97589a8385e15ea2d2a","access_level":"open_access","date_updated":"2024-07-22T09:38:15Z","file_size":351796,"file_id":"17299"}],"has_accepted_license":"1","ddc":["510"],"article_type":"original","oa_version":"Published Version","intvolume":" 389","acknowledgement":"The research of A.V. is supported by NSF DMS-1900286, DMS-2154402 and by Hausdorff Center for Mathematics. H.Z. is supported by the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337. This work is partially supported by NSF DMS-1929284 while both authors were in residence at the Institute for Computational and Experimental Research in Mathematics in Providence, RI, during the Harmonic Analysis and Convexity program.","type":"journal_article","_id":"13318","scopus_import":"1","isi":1,"oa":1,"file_date_updated":"2024-07-22T09:38:15Z","month":"06","language":[{"iso":"eng"}],"date_published":"2024-06-01T00:00:00Z","arxiv":1,"department":[{"_id":"JaMa"}],"publisher":"Springer Nature","date_updated":"2025-04-23T07:50:55Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"status":"public","day":"01","citation":{"short":"A. Volberg, H. Zhang, Mathematische Annalen 389 (2024) 1657–1676.","ieee":"A. Volberg and H. Zhang, “Noncommutative Bohnenblust–Hille inequalities,” Mathematische Annalen, vol. 389. Springer Nature, pp. 1657–1676, 2024.","ama":"Volberg A, Zhang H. Noncommutative Bohnenblust–Hille inequalities. Mathematische Annalen. 2024;389:1657-1676. doi:10.1007/s00208-023-02680-0","ista":"Volberg A, Zhang H. 2024. Noncommutative Bohnenblust–Hille inequalities. Mathematische Annalen. 389, 1657–1676.","chicago":"Volberg, Alexander, and Haonan Zhang. “Noncommutative Bohnenblust–Hille Inequalities.” Mathematische Annalen. Springer Nature, 2024. https://doi.org/10.1007/s00208-023-02680-0.","apa":"Volberg, A., & Zhang, H. (2024). Noncommutative Bohnenblust–Hille inequalities. Mathematische Annalen. Springer Nature. https://doi.org/10.1007/s00208-023-02680-0","mla":"Volberg, Alexander, and Haonan Zhang. “Noncommutative Bohnenblust–Hille Inequalities.” Mathematische Annalen, vol. 389, Springer Nature, 2024, pp. 1657–76, doi:10.1007/s00208-023-02680-0."},"project":[{"name":"Curvature-dimension in noncommutative analysis","grant_number":"M03337","_id":"eb958bca-77a9-11ec-83b8-c565cb50d8d6"}]},{"_id":"21064","scopus_import":"1","acknowledgement":"I.L. acknowledges support from Australian Research Council Future Fellowship FT220100798. J.E.G. and A.D.G acknowledge support from NSF/AAG grant #1007094, and J.E.G. also acknowledges support from NSF/AAG grant #1007052. L.J.F. and A.Z. acknowledge support by Grant No. 2020750 from the United States–Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Ministry of Science & Technology of Israel. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. P.D. acknowledges support from the NWO grant 016.VIDI.189.162 (“ODIN”) and from the European Commission’s and University of Groningen’s CO-FUND Rosalind Franklin program. R.P.N. acknowledges funding from JWST programs GO-1933 and GO-2279. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. This paper makes use of the ALMA data: ADS/JAO. ALMA #2022.1.00073.S, 2018.1.00035.L, and 2013.1.00999.S. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. The research of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation.","type":"journal_article","article_type":"original","intvolume":" 978","oa_version":"Published Version","arxiv":1,"department":[{"_id":"JoMa"}],"publisher":"IOP Publishing","date_updated":"2026-02-10T06:49:49Z","language":[{"iso":"eng"}],"month":"12","date_published":"2024-12-26T00:00:00Z","oa":1,"DOAJ_listed":"1","file_date_updated":"2026-02-10T06:44:24Z","day":"26","status":"public","OA_type":"gold","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"PlanS_conform":"1","citation":{"ista":"Labbe I, Greene JE, Bezanson R, Fujimoto S, Furtak LJ, Goulding AD, Matthee JJ, Naidu RP, Oesch PA, Atek H, Brammer G, Chemerynska I, Coe D, Cutler SE, Dayal P, Feldmann R, Franx M, Glazebrook K, Leja J, Maseda M, Marchesini D, Nanayakkara T, Nelson EJ, Pan R, Papovich C, Price SH, Suess KA, Wang B冰洁, Weaver JR, Whitaker KE, Williams CC, Zitrin A. 2024. UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA. The Astrophysical Journal. 978, 92.","ama":"Labbe I, Greene JE, Bezanson R, et al. UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA. The Astrophysical Journal. 2024;978. doi:10.3847/1538-4357/ad3551","ieee":"I. Labbe et al., “UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA,” The Astrophysical Journal, vol. 978. IOP Publishing, 2024.","short":"I. Labbe, J.E. Greene, R. Bezanson, S. Fujimoto, L.J. Furtak, A.D. Goulding, J.J. Matthee, R.P. Naidu, P.A. Oesch, H. Atek, G. Brammer, I. Chemerynska, D. Coe, S.E. Cutler, P. Dayal, R. Feldmann, M. Franx, K. Glazebrook, J. Leja, M. Maseda, D. Marchesini, T. Nanayakkara, E.J. Nelson, R. Pan, C. Papovich, S.H. Price, K.A. Suess, B.冰洁 Wang, J.R. Weaver, K.E. Whitaker, C.C. Williams, A. Zitrin, The Astrophysical Journal 978 (2024).","mla":"Labbe, Ivo, et al. “UNCOVER: Candidate Red Active Galactic Nuclei at 3 < z < 7 with JWST and ALMA.” The Astrophysical Journal, vol. 978, 92, IOP Publishing, 2024, doi:10.3847/1538-4357/ad3551.","chicago":"Labbe, Ivo, Jenny E. Greene, Rachel Bezanson, Seiji Fujimoto, Lukas J. Furtak, Andy D. Goulding, Jorryt J Matthee, et al. “UNCOVER: Candidate Red Active Galactic Nuclei at 3 < z < 7 with JWST and ALMA.” The Astrophysical Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad3551.","apa":"Labbe, I., Greene, J. E., Bezanson, R., Fujimoto, S., Furtak, L. J., Goulding, A. D., … Zitrin, A. (2024). UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA. The Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ad3551"},"volume":978,"OA_place":"publisher","author":[{"full_name":"Labbe, Ivo","last_name":"Labbe","first_name":"Ivo"},{"full_name":"Greene, Jenny E.","last_name":"Greene","first_name":"Jenny E."},{"last_name":"Bezanson","first_name":"Rachel","full_name":"Bezanson, Rachel"},{"full_name":"Fujimoto, Seiji","last_name":"Fujimoto","first_name":"Seiji"},{"first_name":"Lukas J.","last_name":"Furtak","full_name":"Furtak, Lukas J."},{"first_name":"Andy D.","last_name":"Goulding","full_name":"Goulding, Andy D."},{"id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","last_name":"Matthee","first_name":"Jorryt J"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"first_name":"Pascal A.","last_name":"Oesch","full_name":"Oesch, Pascal A."},{"last_name":"Atek","first_name":"Hakim","full_name":"Atek, Hakim"},{"last_name":"Brammer","first_name":"Gabriel","full_name":"Brammer, Gabriel"},{"full_name":"Chemerynska, Iryna","last_name":"Chemerynska","first_name":"Iryna"},{"full_name":"Coe, Dan","first_name":"Dan","last_name":"Coe"},{"last_name":"Cutler","first_name":"Sam E.","full_name":"Cutler, Sam E."},{"last_name":"Dayal","first_name":"Pratika","full_name":"Dayal, Pratika"},{"first_name":"Robert","last_name":"Feldmann","full_name":"Feldmann, Robert"},{"full_name":"Franx, Marijn","first_name":"Marijn","last_name":"Franx"},{"first_name":"Karl","last_name":"Glazebrook","full_name":"Glazebrook, Karl"},{"last_name":"Leja","first_name":"Joel","full_name":"Leja, Joel"},{"last_name":"Maseda","first_name":"Michael","full_name":"Maseda, Michael"},{"full_name":"Marchesini, Danilo","first_name":"Danilo","last_name":"Marchesini"},{"full_name":"Nanayakkara, Themiya","first_name":"Themiya","last_name":"Nanayakkara"},{"first_name":"Erica J.","last_name":"Nelson","full_name":"Nelson, Erica J."},{"last_name":"Pan","first_name":"Richard","full_name":"Pan, Richard"},{"last_name":"Papovich","first_name":"Casey","full_name":"Papovich, Casey"},{"full_name":"Price, Sedona H.","first_name":"Sedona H.","last_name":"Price"},{"full_name":"Suess, Katherine A.","last_name":"Suess","first_name":"Katherine A."},{"full_name":"Wang, Bingjie 冰洁","first_name":"Bingjie 冰洁","last_name":"Wang"},{"first_name":"John R.","last_name":"Weaver","full_name":"Weaver, John R."},{"full_name":"Whitaker, Katherine E.","last_name":"Whitaker","first_name":"Katherine E."},{"last_name":"Williams","first_name":"Christina C.","full_name":"Williams, Christina C."},{"first_name":"Adi","last_name":"Zitrin","full_name":"Zitrin, Adi"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA","abstract":[{"text":"The James Webb Space Telescope (JWST) is revolutionizing our knowledge of z > 5 galaxies and their actively accreting black holes. Using the JWST Cycle 1 Treasury program Ultradeep NIRSpec and NIRCam Observations before the Epoch of Reionization (UNCOVER) in the lensing field A2744, we report the identification of a sample of little red dots at 3 < zphot < 7 that likely contain highly reddened accreting supermassive black holes. Using a NIRCam-only selection to F444W < 27.7 mag, we find 26 sources over the ∼45 arcmin^2 field that are blue in F115W − F200W ∼ 0 (or βUV ∼ –2.0 for fλ ∝ λ^β), red in F200W − F444W = 1−4 (βopt ∼ +2.0), and are dominated by a point-source-like central component. Of the 20 sources with deep Atacama Large Millimeter/submillimeter Array (ALMA) 1.2 mm coverage, none are detected individually or in a stack. For the majority of the sample, spectral energy distribution fits to the JWST+ALMA observations prefer models with hot dust rather than obscured star formation to reproduce the red NIRCam colors and ALMA 1.2 mm nondetections. While compact dusty star formation cannot be ruled out, the combination of extremely small sizes (〈re〉 ≈ 50 pc after correction for magnification), red rest-frame optical slopes, and hot dust can be explained by reddened broad-line active galactic nuclei (AGNs). Our targets have faint M1450 ≈ −14 to −18 mag but inferred bolometric luminosities of Lbol = 10^43–10^46 erg s^−1, reflecting their obscured nature. If the candidates are confirmed as AGNs with upcoming UNCOVER spectroscopy, then we have found an abundant population of reddened luminous AGNs that are at least ten times more numerous than UV-luminous AGNs at the same intrinsic bolometric luminosity.","lang":"eng"}],"publication_status":"published","external_id":{"arxiv":["2306.07320"]},"article_processing_charge":"Yes","publication":"The Astrophysical Journal","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"doi":"10.3847/1538-4357/ad3551","article_number":"92","year":"2024","date_created":"2026-01-28T15:26:12Z","ddc":["520"],"has_accepted_license":"1","file":[{"date_updated":"2026-02-10T06:44:24Z","file_size":5041924,"access_level":"open_access","relation":"main_file","checksum":"825c35ebd26e292c8a5c2bffac327854","file_id":"21201","success":1,"creator":"dernst","content_type":"application/pdf","file_name":"2024_AstrophysicalJourn_Labbe.pdf","date_created":"2026-02-10T06:44:24Z"}],"quality_controlled":"1"},{"article_processing_charge":"No","oa":1,"abstract":[{"lang":"eng","text":"No description provided."}],"title":"archaeal_membranes : code and examples","month":"10","date_published":"2024-10-15T00:00:00Z","department":[{"_id":"AnSa"}],"publisher":"Zenodo","date_updated":"2026-02-23T11:49:05Z","author":[{"last_name":"Santana de Freitas Amaral","first_name":"Miguel","full_name":"Santana de Freitas Amaral, Miguel","id":"4f2d02dd-47a9-11ec-ad10-82820ed3f501"}],"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"repository","type":"research_data_reference","_id":"21304","related_material":{"record":[{"relation":"used_for_analysis_in","id":"21251","status":"public"}]},"corr_author":"1","citation":{"ieee":"M. Santana de Freitas Amaral, “archaeal_membranes : code and examples.” Zenodo, 2024.","short":"M. Santana de Freitas Amaral, (2024).","ama":"Santana de Freitas Amaral M. archaeal_membranes : code and examples. 2024. doi:10.5281/ZENODO.13934991","ista":"Santana de Freitas Amaral M. 2024. archaeal_membranes : code and examples, Zenodo, 10.5281/ZENODO.13934991.","apa":"Santana de Freitas Amaral, M. (2024). archaeal_membranes : code and examples. Zenodo. https://doi.org/10.5281/ZENODO.13934991","chicago":"Santana de Freitas Amaral, Miguel. “Archaeal_membranes : Code and Examples.” Zenodo, 2024. https://doi.org/10.5281/ZENODO.13934991.","mla":"Santana de Freitas Amaral, Miguel. Archaeal_membranes : Code and Examples. Zenodo, 2024, doi:10.5281/ZENODO.13934991."},"has_accepted_license":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5281/ZENODO.13934991"}],"year":"2024","date_created":"2026-02-17T12:52:26Z","OA_type":"green","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"doi":"10.5281/ZENODO.13934991","day":"15","status":"public"},{"corr_author":"1","citation":{"mla":"Khudiakova, Kseniia, et al. “Genealogies under Purifying Selection.” BioRxiv, doi:10.1101/2024.10.15.618444.","chicago":"Khudiakova, Kseniia, Florin Boenkost, and Julie N Tourniaire. “Genealogies under Purifying Selection.” BioRxiv, n.d. https://doi.org/10.1101/2024.10.15.618444.","apa":"Khudiakova, K., Boenkost, F., & Tourniaire, J. N. (n.d.). Genealogies under purifying selection. bioRxiv. https://doi.org/10.1101/2024.10.15.618444","ama":"Khudiakova K, Boenkost F, Tourniaire JN. Genealogies under purifying selection. bioRxiv. doi:10.1101/2024.10.15.618444","ista":"Khudiakova K, Boenkost F, Tourniaire JN. Genealogies under purifying selection. bioRxiv, 10.1101/2024.10.15.618444.","short":"K. Khudiakova, F. Boenkost, J.N. Tourniaire, BioRxiv (n.d.).","ieee":"K. Khudiakova, F. Boenkost, and J. N. Tourniaire, “Genealogies under purifying selection,” bioRxiv. ."},"project":[{"name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8","grant_number":"26293"},{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2024.10.15.618444"}],"year":"2024","date_created":"2026-06-09T12:14:08Z","OA_type":"green","ec_funded":1,"tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"doi":"10.1101/2024.10.15.618444","status":"public","day":"18","publication":"bioRxiv","article_processing_charge":"No","abstract":[{"text":"Selection against deleterious mutations, called purifying selection, plays a central role in evolution and acts in all populations. It is known that the genetic patterns observed in genomic regions undergoing purifying selection differ from those resulting from neutral evolution. However, a comprehensive understanding of the underlying mechanisms shaping those patterns is still lacking.\r\n\r\nIn the present work, we use simulations combined with a genealogical approach to identify the effect of purifying selection on the ancestry and thus on the genetic diversity. Our analysis relies on the postulate that the genealogy belongs to the universality class of Beta-coalescents. Under this assumption, we derive statistics measuring the distortion of the genealogy. This approach allows us to consider a wide range of regimes (i.e. arbitrary selection and mutation strengths) and uncover a rich phase diagram. We find that, for strong selection, the limiting genealogy is given by Kingman’s coalescent on a polynomial timescale. As selection gets weaker, Muller’s ratchet starts operating, setting off the emergence of multiple mergers in the genealogical structures. Our results show that while multiple-merger coalescents are often interpreted as the signature of selective sweeps in rapidly adapting populations, these structures can also appear in the context of Muller’s ratchet.","lang":"eng"}],"oa":1,"publication_status":"draft","language":[{"iso":"eng"}],"month":"10","title":"Genealogies under purifying selection","date_published":"2024-10-18T00:00:00Z","department":[{"_id":"NiBa"},{"_id":"JaMa"}],"date_updated":"2026-06-12T12:43:34Z","author":[{"orcid":"0000-0002-6246-1465","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","full_name":"Khudiakova, Kseniia","last_name":"Khudiakova","first_name":"Kseniia"},{"full_name":"Boenkost, Florin","first_name":"Florin","last_name":"Boenkost"},{"first_name":"Julie N","last_name":"Tourniaire","id":"5dc06dd8-8e51-11ec-9170-8d9c450cc216","full_name":"Tourniaire, Julie N"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa_version":"Preprint","acknowledgement":"This work was supported by the Austrian Academy of Science, DOC fellowship No 26293 (K.K.) and the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413 (J.T.). Simulations were performed on the ISTA High-performance Computing Cluster.","type":"preprint","_id":"21967","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"21918"}]}},{"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1812.04911","open_access":"1"}],"quality_controlled":"1","publication":"Discrete and Computational Geometry","publication_identifier":{"issn":["0179-5376"],"eissn":["1432-0444"]},"doi":"10.1007/s00454-023-00532-x","date_created":"2023-08-06T22:01:12Z","year":"2024","title":"The crossing Tverberg theorem","publication_status":"published","external_id":{"isi":["001038546500001"],"arxiv":["1812.04911"]},"abstract":[{"text":"The Tverberg theorem is one of the cornerstones of discrete geometry. It states that, given a set X of at least (d+1)(r−1)+1 points in Rd, one can find a partition X=X1∪⋯∪Xr of X, such that the convex hulls of the Xi, i=1,…,r, all share a common point. In this paper, we prove a trengthening of this theorem that guarantees a partition which, in addition to the above, has the property that the boundaries of full-dimensional convex hulls have pairwise nonempty intersections. Possible generalizations and algorithmic aspects are also discussed. As a concrete application, we show that any n points in the plane in general position span ⌊n/3⌋ vertex-disjoint triangles that are pairwise crossing, meaning that their boundaries have pairwise nonempty intersections; this number is clearly best possible. A previous result of Álvarez-Rebollar et al. guarantees ⌊n/6⌋pairwise crossing triangles. Our result generalizes to a result about simplices in Rd, d≥2.","lang":"eng"}],"article_processing_charge":"No","page":"831-848","related_material":{"record":[{"id":"6647","relation":"earlier_version","status":"public"}]},"volume":72,"OA_place":"repository","author":[{"last_name":"Fulek","first_name":"Radoslav","orcid":"0000-0001-8485-1774","id":"39F3FFE4-F248-11E8-B48F-1D18A9856A87","full_name":"Fulek, Radoslav"},{"full_name":"Gärtner, Bernd","first_name":"Bernd","last_name":"Gärtner"},{"first_name":"Andrey","last_name":"Kupavskii","full_name":"Kupavskii, Andrey"},{"first_name":"Pavel","last_name":"Valtr","full_name":"Valtr, Pavel"},{"last_name":"Wagner","first_name":"Uli","full_name":"Wagner, Uli","orcid":"0000-0002-1494-0568","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"FWF","name":"Eliminating intersections in drawings of graphs","_id":"261FA626-B435-11E9-9278-68D0E5697425","grant_number":"M02281"}],"citation":{"mla":"Fulek, Radoslav, et al. “The Crossing Tverberg Theorem.” Discrete and Computational Geometry, vol. 72, Springer Nature, 2024, pp. 831–48, doi:10.1007/s00454-023-00532-x.","chicago":"Fulek, Radoslav, Bernd Gärtner, Andrey Kupavskii, Pavel Valtr, and Uli Wagner. “The Crossing Tverberg Theorem.” Discrete and Computational Geometry. Springer Nature, 2024. https://doi.org/10.1007/s00454-023-00532-x.","apa":"Fulek, R., Gärtner, B., Kupavskii, A., Valtr, P., & Wagner, U. (2024). The crossing Tverberg theorem. Discrete and Computational Geometry. Springer Nature. https://doi.org/10.1007/s00454-023-00532-x","ama":"Fulek R, Gärtner B, Kupavskii A, Valtr P, Wagner U. The crossing Tverberg theorem. Discrete and Computational Geometry. 2024;72:831-848. doi:10.1007/s00454-023-00532-x","ista":"Fulek R, Gärtner B, Kupavskii A, Valtr P, Wagner U. 2024. The crossing Tverberg theorem. Discrete and Computational Geometry. 72, 831–848.","short":"R. Fulek, B. Gärtner, A. Kupavskii, P. Valtr, U. Wagner, Discrete and Computational Geometry 72 (2024) 831–848.","ieee":"R. Fulek, B. Gärtner, A. Kupavskii, P. Valtr, and U. Wagner, “The crossing Tverberg theorem,” Discrete and Computational Geometry, vol. 72. Springer Nature, pp. 831–848, 2024."},"status":"public","day":"01","OA_type":"green","date_updated":"2025-04-14T13:52:36Z","department":[{"_id":"UlWa"}],"arxiv":1,"publisher":"Springer Nature","date_published":"2024-09-01T00:00:00Z","language":[{"iso":"eng"}],"month":"09","oa":1,"isi":1,"scopus_import":"1","_id":"13974","acknowledgement":"Part of the research leading to this paper was done during the 16th Gremo Workshop on Open Problems (GWOP), Waltensburg, Switzerland, June 12–16, 2018. We thank Patrick Schnider for suggesting the problem, and Stefan Felsner, Malte Milatz, and Emo Welzl for fruitful discussions during the workshop. We also thank Stefan Felsner and Manfred Scheucher for finding, communicating the example from Sect. 3.3, and the kind permission to include their visualization of the point set. We thank Dömötör Pálvölgyi, the SoCG reviewers, and DCG reviewers for various helpful comments.\r\nR. Fulek gratefully acknowledges support from Austrian Science Fund (FWF), Project M2281-N35. A. Kupavskii was supported by the Advanced Postdoc.Mobility Grant no. P300P2_177839 of the Swiss National Science Foundation. Research by P. Valtr was supported by the Grant no. 18-19158 S of the Czech Science Foundation (GAČR).","type":"journal_article","oa_version":"Preprint","intvolume":" 72","article_type":"original"},{"volume":37,"author":[{"last_name":"Campbell","first_name":"Andrew J","id":"582b06a9-1f1c-11ee-b076-82ffce00dde4","full_name":"Campbell, Andrew J"},{"full_name":"O’Rourke, Sean","first_name":"Sean","last_name":"O’Rourke"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Spectrum of Lévy–Khintchine random laplacian matrices","external_id":{"isi":["001038341000001"],"arxiv":["2210.07927"]},"publication_status":"published","abstract":[{"lang":"eng","text":"We consider the spectrum of random Laplacian matrices of the form Ln=An−Dn where An\r\n is a real symmetric random matrix and Dn is a diagonal matrix whose entries are equal to the corresponding row sums of An. If An is a Wigner matrix with entries in the domain of attraction of a Gaussian distribution, the empirical spectral measure of Ln is known to converge to the free convolution of a semicircle distribution and a standard real Gaussian distribution. We consider real symmetric random matrices An with independent entries (up to symmetry) whose row sums converge to a purely non-Gaussian infinitely divisible distribution, which fall into the class of Lévy–Khintchine random matrices first introduced by Jung [Trans Am Math Soc, 370, (2018)]. Our main result shows that the empirical spectral measure of Ln converges almost surely to a deterministic limit. A key step in the proof is to use the purely non-Gaussian nature of the row sums to build a random operator to which Ln converges in an appropriate sense. This operator leads to a recursive distributional equation uniquely describing the Stieltjes transform of the limiting empirical spectral measure."}],"article_processing_charge":"Yes (via OA deal)","page":"933-973","publication":"Journal of Theoretical Probability","publication_identifier":{"eissn":["1572-9230"],"issn":["0894-9840"]},"doi":"10.1007/s10959-023-01275-4","date_created":"2023-08-06T22:01:13Z","year":"2024","ddc":["510"],"has_accepted_license":"1","quality_controlled":"1","file":[{"file_id":"17300","date_updated":"2024-07-22T09:41:21Z","file_size":555070,"access_level":"open_access","checksum":"f7793d313104c70422140c5e6494c779","relation":"main_file","content_type":"application/pdf","file_name":"2024_JourTheorProbab_Campbell.pdf","date_created":"2024-07-22T09:41:21Z","success":1,"creator":"dernst"}],"corr_author":"1","scopus_import":"1","_id":"13975","acknowledgement":"The first author thanks Yizhe Zhu for pointing out reference [30]. We thank David Renfrew for comments on an earlier draft. We thank the anonymous referee for a careful reading and helpful comments.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria).","type":"journal_article","intvolume":" 37","oa_version":"Published Version","article_type":"original","date_updated":"2024-07-22T09:41:42Z","department":[{"_id":"LaEr"}],"arxiv":1,"publisher":"Springer Nature","date_published":"2024-03-01T00:00:00Z","language":[{"iso":"eng"}],"month":"03","file_date_updated":"2024-07-22T09:41:21Z","oa":1,"isi":1,"day":"01","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"citation":{"ista":"Campbell AJ, O’Rourke S. 2024. Spectrum of Lévy–Khintchine random laplacian matrices. Journal of Theoretical Probability. 37, 933–973.","ama":"Campbell AJ, O’Rourke S. Spectrum of Lévy–Khintchine random laplacian matrices. Journal of Theoretical Probability. 2024;37:933-973. doi:10.1007/s10959-023-01275-4","short":"A.J. Campbell, S. O’Rourke, Journal of Theoretical Probability 37 (2024) 933–973.","ieee":"A. J. Campbell and S. O’Rourke, “Spectrum of Lévy–Khintchine random laplacian matrices,” Journal of Theoretical Probability, vol. 37. Springer Nature, pp. 933–973, 2024.","mla":"Campbell, Andrew J., and Sean O’Rourke. “Spectrum of Lévy–Khintchine Random Laplacian Matrices.” Journal of Theoretical Probability, vol. 37, Springer Nature, 2024, pp. 933–73, doi:10.1007/s10959-023-01275-4.","chicago":"Campbell, Andrew J, and Sean O’Rourke. “Spectrum of Lévy–Khintchine Random Laplacian Matrices.” Journal of Theoretical Probability. Springer Nature, 2024. https://doi.org/10.1007/s10959-023-01275-4.","apa":"Campbell, A. J., & O’Rourke, S. (2024). Spectrum of Lévy–Khintchine random laplacian matrices. Journal of Theoretical Probability. Springer Nature. https://doi.org/10.1007/s10959-023-01275-4"}},{"citation":{"ista":"Lao D, Hu Z, Locatello F, Yang Y, Soatto S. 2024. Divided attention: Unsupervised multi-object discovery with contextually separated slots. 1st Conference on Parsimony and Learning. CPAL: Conference on Parsimony and Learning.","ama":"Lao D, Hu Z, Locatello F, Yang Y, Soatto S. Divided attention: Unsupervised multi-object discovery with contextually separated slots. In: 1st Conference on Parsimony and Learning. ; 2024.","ieee":"D. Lao, Z. Hu, F. Locatello, Y. Yang, and S. Soatto, “Divided attention: Unsupervised multi-object discovery with contextually separated slots,” in 1st Conference on Parsimony and Learning, Hong Kong, China, 2024.","short":"D. Lao, Z. Hu, F. Locatello, Y. Yang, S. Soatto, in:, 1st Conference on Parsimony and Learning, 2024.","mla":"Lao, Dong, et al. “Divided Attention: Unsupervised Multi-Object Discovery with Contextually Separated Slots.” 1st Conference on Parsimony and Learning, 2024.","apa":"Lao, D., Hu, Z., Locatello, F., Yang, Y., & Soatto, S. (2024). Divided attention: Unsupervised multi-object discovery with contextually separated slots. In 1st Conference on Parsimony and Learning. Hong Kong, China.","chicago":"Lao, Dong, Zhengyang Hu, Francesco Locatello, Yanchao Yang, and Stefano Soatto. “Divided Attention: Unsupervised Multi-Object Discovery with Contextually Separated Slots.” In 1st Conference on Parsimony and Learning, 2024."},"file":[{"content_type":"application/pdf","file_name":"2024_CPAL_Lao.pdf","date_created":"2024-02-12T08:40:36Z","success":1,"creator":"dernst","file_id":"14978","file_size":8038511,"date_updated":"2024-02-12T08:40:36Z","access_level":"open_access","checksum":"8fad894c34f1b3d5a14fb8ffb12f7277","relation":"main_file"}],"quality_controlled":"1","has_accepted_license":"1","conference":{"location":"Hong Kong, China","end_date":"2024-01-03","start_date":"2024-01-03","name":"CPAL: Conference on Parsimony and Learning"},"ddc":["000"],"date_created":"2023-08-22T14:19:59Z","year":"2024","status":"public","day":"03","publication":"1st Conference on Parsimony and Learning","article_processing_charge":"No","publication_status":"published","file_date_updated":"2024-02-12T08:40:36Z","external_id":{"arxiv":["2304.01430"]},"oa":1,"abstract":[{"lang":"eng","text":"We introduce a method to segment the visual field into independently moving regions, trained with no ground truth or supervision. It consists of an adversarial conditional encoder-decoder architecture based on Slot Attention, modified to use the image as context to decode optical flow without attempting to reconstruct the image itself. In the resulting multi-modal representation, one modality (flow) feeds the encoder to produce separate latent codes (slots), whereas the other modality (image) conditions the decoder to generate the first (flow) from the slots. This design frees the representation from having to encode complex nuisance variability in the image due to, for instance, illumination and reflectance properties of the scene. Since customary autoencoding based on minimizing the reconstruction error does not preclude the entire flow from being encoded into a single slot, we modify the loss to an adversarial criterion based on Contextual Information Separation. The resulting min-max optimization fosters the separation of objects and their assignment to different attention slots, leading to Divided Attention, or DivA. DivA outperforms recent unsupervised multi-object motion segmentation methods while tripling run-time speed up to 104FPS and reducing the performance gap from supervised methods to 12% or less. DivA can handle different numbers of objects and different image sizes at training and test time, is invariant to permutation of object labels, and does not require explicit regularization."}],"date_published":"2024-01-03T00:00:00Z","title":"Divided attention: Unsupervised multi-object discovery with contextually separated slots","language":[{"iso":"eng"}],"month":"01","date_updated":"2024-02-12T08:56:23Z","department":[{"_id":"FrLo"}],"arxiv":1,"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Lao","first_name":"Dong","full_name":"Lao, Dong"},{"full_name":"Hu, Zhengyang","first_name":"Zhengyang","last_name":"Hu"},{"first_name":"Francesco","last_name":"Locatello","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","orcid":"0000-0002-4850-0683","full_name":"Locatello, Francesco"},{"last_name":"Yang","first_name":"Yanchao","full_name":"Yang, Yanchao"},{"first_name":"Stefano","last_name":"Soatto","full_name":"Soatto, Stefano"}],"type":"conference","_id":"14213"},{"pmid":1,"author":[{"first_name":"Han","last_name":"Tang","id":"19BDF720-25A0-11EA-AC6E-928F3DDC885E","orcid":"0000-0001-6152-6637","full_name":"Tang, Han"},{"full_name":"Lu, KJ","first_name":"KJ","last_name":"Lu"},{"full_name":"Zhang, Y","last_name":"Zhang","first_name":"Y"},{"full_name":"Cheng, YL","last_name":"Cheng","first_name":"YL"},{"first_name":"SL","last_name":"Tu","full_name":"Tu, SL"},{"first_name":"Jiří","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","volume":5,"title":"Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution","article_processing_charge":"Yes","abstract":[{"text":"The phytohormone auxin and its directional transport through tissues play a fundamental role in development of higher plants. This polar auxin transport predominantly relies on PIN-FORMED (PIN) auxin exporters. Hence, PIN polarization is crucial for development, but its evolution during the rise of morphological complexity in land plants remains unclear. Here, we performed a cross-species investigation by observing the trafficking and localization of endogenous and exogenous PINs in two bryophytes, Physcomitrium patens and Marchantia polymorpha, and in the flowering plant Arabidopsis thaliana. We confirmed that the GFP fusion did not compromise the auxin export function of all examined PINs by using radioactive auxin export assay and by observing the phenotypic changes in transgenic bryophytes. Endogenous PINs polarize to filamentous apices, while exogenous Arabidopsis PINs distribute symmetrically on the membrane in both bryophytes. In Arabidopsis root epidermis, bryophytic PINs show no defined polarity. Pharmacological interference revealed a strong cytoskeleton dependence of bryophytic but not Arabidopsis PIN polarization. The divergence of PIN polarization and trafficking is also observed within the bryophyte clade and between tissues of individual species. These results collectively reveal a divergence of PIN trafficking and polarity mechanisms throughout land plant evolution and a co-evolution of PIN sequence-based and cell-based polarity mechanisms.","lang":"eng"}],"external_id":{"pmid":["37528584"],"isi":["001158054500001"]},"publication_status":"published","issue":"1","doi":"10.1016/j.xplc.2023.100669","publication_identifier":{"issn":["2590-3462"]},"publication":"Plant Communications","year":"2024","date_created":"2023-09-01T11:32:02Z","article_number":"100669","has_accepted_license":"1","ddc":["580"],"corr_author":"1","quality_controlled":"1","file":[{"date_created":"2024-01-30T12:59:57Z","content_type":"application/pdf","file_name":"2023_PlantCommunications_Tang.pdf","creator":"dernst","success":1,"file_id":"14911","checksum":"edbc44c6d4a394d2bf70f92fdbb08f0a","relation":"main_file","access_level":"open_access","file_size":2825565,"date_updated":"2024-01-30T12:59:57Z"}],"_id":"14251","scopus_import":"1","article_type":"original","intvolume":" 5","oa_version":"Published Version","acknowledgement":"This work was supported by the ERC grant (PR1023ERC02) to H. T. and J. F., and by the ministry of science and technology (grant number 110-2636-B-005-001) to K. J. L.","type":"journal_article","language":[{"iso":"eng"}],"month":"01","date_published":"2024-01-08T00:00:00Z","publisher":"Elsevier","department":[{"_id":"JiFr"}],"date_updated":"2025-08-05T13:27:26Z","isi":1,"oa":1,"file_date_updated":"2024-01-30T12:59:57Z","DOAJ_listed":"1","status":"public","day":"08","OA_type":"gold","ec_funded":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"citation":{"chicago":"Tang, Han, KJ Lu, Y Zhang, YL Cheng, SL Tu, and Jiří Friml. “Divergence of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land Plant Evolution.” Plant Communications. Elsevier, 2024. https://doi.org/10.1016/j.xplc.2023.100669.","apa":"Tang, H., Lu, K., Zhang, Y., Cheng, Y., Tu, S., & Friml, J. (2024). Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. Elsevier. https://doi.org/10.1016/j.xplc.2023.100669","mla":"Tang, Han, et al. “Divergence of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land Plant Evolution.” Plant Communications, vol. 5, no. 1, 100669, Elsevier, 2024, doi:10.1016/j.xplc.2023.100669.","ieee":"H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, and J. Friml, “Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution,” Plant Communications, vol. 5, no. 1. Elsevier, 2024.","short":"H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, J. Friml, Plant Communications 5 (2024).","ama":"Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. 2024;5(1). doi:10.1016/j.xplc.2023.100669","ista":"Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. 2024. Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. 5(1), 100669."},"project":[{"call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","_id":"261099A6-B435-11E9-9278-68D0E5697425","grant_number":"742985"}]},{"type":"journal_article","acknowledgement":"We thank J. Vorlaufer, N. Agudelo-Dueñas, W. Jahr and A. Wartak for microscope maintenance and troubleshooting; C. Kreuzinger, A. Freeman and I. Erber for technical assistance; and M. Tomschik for support with obtaining human samples. We gratefully acknowledge E. Miguel for setting up webKnossos and M. Šuplata for computational support and hardware control. We are grateful to R. Shigemoto and B. Bickel for generous support and M. Sixt and S. Boyd (Stanford University) for discussions and critical reading of the paper. PSD95-HaloTag mice were kindly provided by S. Grant (University of Edinburgh). We acknowledge expert support by Institute of Science and Technology Austria’s scientific computing, imaging and optics, preclinical and lab support facilities and by the Miba machine shop and library. We gratefully acknowledge funding by the following sources: Austrian Science Fund (FWF) grant I3600-B27 (J.G.D.); Austrian Science Fund (FWF) grant DK W1232 (J.G.D. and J.M.M.); Austrian Science Fund (FWF) grant Z 312-B27, Wittgenstein award (P.J.); Austrian Science Fund (FWF) projects I4685-B, I6565-B (SYNABS) and DOC 33-B27 (R.H.); Gesellschaft für Forschungsförderung NÖ (NFB) grant LSC18-022 (J.G.D.); European Union’s Horizon 2020 research and innovation programme, European Research Council (ERC) grant 715508 – REVERSEAUTISM (G.N.); European Union’s Horizon 2020 research and innovation programme, European Research Council (ERC) grant 692692 – GIANTSYN (P.J.); Marie Skłodowska-Curie Actions Fellowship GA no. 665385 under the EU Horizon 2020 program (J.M.M. and J.L.); and Marie Skłodowska-Curie Actions Individual Fellowship no. 101026635 under the EU Horizon 2020 program (J.F.W.).","intvolume":" 42","oa_version":"Published Version","article_type":"original","scopus_import":"1","_id":"14257","file_date_updated":"2025-01-09T07:48:01Z","oa":1,"isi":1,"date_updated":"2026-04-14T08:34:35Z","publisher":"Springer Nature","department":[{"_id":"SaSi"},{"_id":"GaNo"},{"_id":"PeJo"},{"_id":"JoDa"},{"_id":"Bio"},{"_id":"RySh"}],"date_published":"2024-07-01T00:00:00Z","month":"07","language":[{"iso":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"ec_funded":1,"OA_type":"hybrid","day":"01","status":"public","project":[{"grant_number":"I03600","_id":"265CB4D0-B435-11E9-9278-68D0E5697425","name":"Optical control of synaptic function via adhesion molecules","call_identifier":"FWF"},{"grant_number":"W1232","_id":"2548AE96-B435-11E9-9278-68D0E5697425","name":"Molecular Drug Targets","call_identifier":"FWF"},{"call_identifier":"FWF","name":"Synaptic communication in neuronal microcircuits","_id":"25C5A090-B435-11E9-9278-68D0E5697425","grant_number":"Z00312"},{"name":"High content imaging to decode human immune cell interactions in health and allergic disease","grant_number":"LS18-022","_id":"23889792-32DE-11EA-91FC-C7463DDC885E"},{"_id":"25444568-B435-11E9-9278-68D0E5697425","grant_number":"715508","call_identifier":"H2020","name":"Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models"},{"call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","grant_number":"692692"},{"name":"International IST Doctoral Program","call_identifier":"H2020","grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","name":"Synaptic computations of the hippocampal CA3 circuitry","_id":"fc2be41b-9c52-11eb-aca3-faa90aa144e9","grant_number":"101026635"}],"citation":{"mla":"Michalska, Julia M., et al. “Imaging Brain Tissue Architecture across Millimeter to Nanometer Scales.” Nature Biotechnology, vol. 42, Springer Nature, 2024, pp. 1051–64, doi:10.1038/s41587-023-01911-8.","chicago":"Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Imaging Brain Tissue Architecture across Millimeter to Nanometer Scales.” Nature Biotechnology. Springer Nature, 2024. https://doi.org/10.1038/s41587-023-01911-8.","apa":"Michalska, J. M., Lyudchik, J., Velicky, P., Korinkova, H., Watson, J., Cenameri, A., … Danzl, J. G. (2024). Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. Springer Nature. https://doi.org/10.1038/s41587-023-01911-8","ama":"Michalska JM, Lyudchik J, Velicky P, et al. Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. 2024;42:1051-1064. doi:10.1038/s41587-023-01911-8","ista":"Michalska JM, Lyudchik J, Velicky P, Korinkova H, Watson J, Cenameri A, Sommer CM, Amberg N, Venturino A, Roessler K, Czech T, Höftberger R, Siegert S, Novarino G, Jonas PM, Danzl JG. 2024. Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. 42, 1051–1064.","ieee":"J. M. Michalska et al., “Imaging brain tissue architecture across millimeter to nanometer scales,” Nature Biotechnology, vol. 42. Springer Nature, pp. 1051–1064, 2024.","short":"J.M. Michalska, J. Lyudchik, P. Velicky, H. Korinkova, J. Watson, A. Cenameri, C.M. Sommer, N. Amberg, A. Venturino, K. Roessler, T. Czech, R. Höftberger, S. Siegert, G. Novarino, P.M. Jonas, J.G. Danzl, Nature Biotechnology 42 (2024) 1051–1064."},"volume":42,"OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Michalska","first_name":"Julia M","full_name":"Michalska, Julia M","orcid":"0000-0003-3862-1235","id":"443DB6DE-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Lyudchik, Julia","id":"46E28B80-F248-11E8-B48F-1D18A9856A87","first_name":"Julia","last_name":"Lyudchik"},{"id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2340-7431","full_name":"Velicky, Philipp","last_name":"Velicky","first_name":"Philipp"},{"last_name":"Korinkova","first_name":"Hana","id":"ee3cb6ca-ec98-11ea-ae11-ff703e2254ed","full_name":"Korinkova, Hana"},{"full_name":"Watson, Jake","orcid":"0000-0002-8698-3823","id":"63836096-4690-11EA-BD4E-32803DDC885E","last_name":"Watson","first_name":"Jake"},{"first_name":"Alban","last_name":"Cenameri","full_name":"Cenameri, Alban","id":"9ac8f577-2357-11eb-997a-e566c5550886"},{"orcid":"0000-0003-1216-9105","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","full_name":"Sommer, Christoph M","first_name":"Christoph M","last_name":"Sommer"},{"id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3183-8207","full_name":"Amberg, Nicole","first_name":"Nicole","last_name":"Amberg"},{"full_name":"Venturino, Alessandro","id":"41CB84B2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2356-9403","last_name":"Venturino","first_name":"Alessandro"},{"first_name":"Karl","last_name":"Roessler","full_name":"Roessler, Karl"},{"full_name":"Czech, Thomas","last_name":"Czech","first_name":"Thomas"},{"last_name":"Höftberger","first_name":"Romana","full_name":"Höftberger, Romana"},{"first_name":"Sandra","last_name":"Siegert","id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8635-0877","full_name":"Siegert, Sandra"},{"id":"3E57A680-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7673-7178","full_name":"Novarino, Gaia","first_name":"Gaia","last_name":"Novarino"},{"first_name":"Peter M","last_name":"Jonas","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804"},{"first_name":"Johann G","last_name":"Danzl","orcid":"0000-0001-8559-3973","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","full_name":"Danzl, Johann G"}],"pmid":1,"related_material":{"record":[{"status":"deleted","id":"18660","relation":"dissertation_contains"},{"status":"public","relation":"research_data","id":"13126"},{"relation":"dissertation_contains","id":"18674","status":"public"}],"link":[{"url":"https://github.com/danzllab/CATS","relation":"software"}]},"acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"Bio"},{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"E-Lib"}],"external_id":{"isi":["001065254200001"],"pmid":["37653226"]},"publication_status":"published","abstract":[{"text":"Mapping the complex and dense arrangement of cells and their connectivity in brain tissue demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels at visualizing specific molecules and individual cells but fails to provide tissue context. Here we developed Comprehensive Analysis of Tissues across Scales (CATS), a technology to densely map brain tissue architecture from millimeter regional to nanometer synaptic scales in diverse chemically fixed brain preparations, including rodent and human. CATS uses fixation-compatible extracellular labeling and optical imaging, including stimulated emission depletion or expansion microscopy, to comprehensively delineate cellular structures. It enables three-dimensional reconstruction of single synapses and mapping of synaptic connectivity by identification and analysis of putative synaptic cleft regions. Applying CATS to the mouse hippocampal mossy fiber circuitry, we reconstructed and quantified the synaptic input and output structure of identified neurons. We furthermore demonstrate applicability to clinically derived human tissue samples, including formalin-fixed paraffin-embedded routine diagnostic specimens, for visualizing the cellular architecture of brain tissue in health and disease.","lang":"eng"}],"article_processing_charge":"Yes (in subscription journal)","page":"1051-1064","title":"Imaging brain tissue architecture across millimeter to nanometer scales","date_created":"2023-09-03T22:01:15Z","year":"2024","publication":"Nature Biotechnology","doi":"10.1038/s41587-023-01911-8","publication_identifier":{"eissn":["1546-1696"],"issn":["1087-0156"]},"file":[{"date_created":"2025-01-09T07:48:01Z","content_type":"application/pdf","file_name":"2024_NatureBiotech_Michalska.pdf","creator":"dernst","success":1,"file_id":"18784","checksum":"57d5fafb16f02dcb9f7dddb1bd7e2a71","relation":"main_file","access_level":"open_access","file_size":26065165,"date_updated":"2025-01-09T07:48:01Z"}],"quality_controlled":"1","corr_author":"1","ddc":["570"],"has_accepted_license":"1"},{"publication":"Discrete and Computational Geometry","publication_identifier":{"issn":["0179-5376"],"eissn":["1432-0444"]},"doi":"10.1007/s00454-023-00566-1","year":"2024","date_created":"2023-09-17T22:01:10Z","ddc":["510"],"has_accepted_license":"1","file":[{"file_name":"2024_DiscreteComputGeom_Edelsbrunner.pdf","content_type":"application/pdf","date_created":"2024-07-22T09:43:19Z","creator":"dernst","success":1,"file_id":"17301","file_size":892019,"date_updated":"2024-07-22T09:43:19Z","checksum":"b207b4e00f904e8ea8a30e24f0251f79","relation":"main_file","access_level":"open_access"}],"quality_controlled":"1","corr_author":"1","pmid":1,"volume":72,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9823-6833","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","first_name":"Herbert"},{"last_name":"Garber","first_name":"Alexey","full_name":"Garber, Alexey"},{"full_name":"Ghafari, Mohadese","last_name":"Ghafari","first_name":"Mohadese"},{"id":"4879BB4E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1780-2689","full_name":"Heiss, Teresa","first_name":"Teresa","last_name":"Heiss"},{"first_name":"Morteza","last_name":"Saghafian","full_name":"Saghafian, Morteza","id":"f86f7148-b140-11ec-9577-95435b8df824"}],"title":"On angles in higher order Brillouin tessellations and related tilings in the plane","abstract":[{"text":"For a locally finite set in R2, the order-k Brillouin tessellations form an infinite sequence of convex face-to-face tilings of the plane. If the set is coarsely dense and generic, then the corresponding infinite sequences of minimum and maximum angles are both monotonic in k. As an example, a stationary Poisson point process in R2 is locally finite, coarsely dense, and generic with probability one. For such a set, the distributions of angles in the Voronoi tessellations, Delaunay mosaics, and Brillouin tessellations are independent of the order and can be derived from the formula for angles in order-1 Delaunay mosaics given by Miles (Math. Biosci. 6, 85–127 (1970)).","lang":"eng"}],"external_id":{"isi":["001060727600004"],"pmid":["39610762"],"arxiv":["2204.01076"]},"publication_status":"published","page":"29-48","article_processing_charge":"Yes (via OA deal)","day":"01","status":"public","ec_funded":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"project":[{"call_identifier":"H2020","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","grant_number":"788183"},{"_id":"268116B8-B435-11E9-9278-68D0E5697425","grant_number":"Z00342","call_identifier":"FWF","name":"Mathematics, Computer Science"},{"name":"Persistence and stability of geometric complexes","call_identifier":"FWF","grant_number":"I02979-N35","_id":"2561EBF4-B435-11E9-9278-68D0E5697425"}],"citation":{"ieee":"H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, and M. Saghafian, “On angles in higher order Brillouin tessellations and related tilings in the plane,” Discrete and Computational Geometry, vol. 72. Springer Nature, pp. 29–48, 2024.","short":"H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, M. Saghafian, Discrete and Computational Geometry 72 (2024) 29–48.","ista":"Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. 2024. On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. 72, 29–48.","ama":"Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. 2024;72:29-48. doi:10.1007/s00454-023-00566-1","apa":"Edelsbrunner, H., Garber, A., Ghafari, M., Heiss, T., & Saghafian, M. (2024). On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. Springer Nature. https://doi.org/10.1007/s00454-023-00566-1","chicago":"Edelsbrunner, Herbert, Alexey Garber, Mohadese Ghafari, Teresa Heiss, and Morteza Saghafian. “On Angles in Higher Order Brillouin Tessellations and Related Tilings in the Plane.” Discrete and Computational Geometry. Springer Nature, 2024. https://doi.org/10.1007/s00454-023-00566-1.","mla":"Edelsbrunner, Herbert, et al. “On Angles in Higher Order Brillouin Tessellations and Related Tilings in the Plane.” Discrete and Computational Geometry, vol. 72, Springer Nature, 2024, pp. 29–48, doi:10.1007/s00454-023-00566-1."},"_id":"14345","scopus_import":"1","acknowledgement":"Work by all authors but A. Garber is supported by the European Research Council (ERC), Grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF), Grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), Grant No. I 02979-N35. Work by A. Garber is partially supported by the Alexander von Humboldt Foundation.","type":"journal_article","article_type":"original","intvolume":" 72","oa_version":"Published Version","department":[{"_id":"HeEd"}],"arxiv":1,"publisher":"Springer Nature","date_updated":"2025-04-23T08:41:59Z","language":[{"iso":"eng"}],"month":"07","date_published":"2024-07-01T00:00:00Z","oa":1,"file_date_updated":"2024-07-22T09:43:19Z","isi":1},{"has_accepted_license":"1","ddc":["000"],"corr_author":"1","quality_controlled":"1","file":[{"file_id":"17258","file_size":1787569,"date_updated":"2024-07-16T10:26:41Z","access_level":"open_access","relation":"main_file","checksum":"4eab70274d1004ea411f7f0e74c033ac","file_name":"2024_NonlinearAnalysis_Majumdar.pdf","content_type":"application/pdf","date_created":"2024-07-16T10:26:41Z","success":1,"creator":"dernst"}],"issue":"2","doi":"10.1016/j.nahs.2023.101430","publication_identifier":{"issn":["1751-570X"]},"publication":"Nonlinear Analysis: Hybrid Systems","year":"2024","date_created":"2023-10-08T22:01:15Z","article_number":"101430","title":"Symbolic control for stochastic systems via finite parity games","article_processing_charge":"Yes (in subscription journal)","abstract":[{"text":"We consider the problem of computing the maximal probability of satisfying an \r\n-regular specification for stochastic, continuous-state, nonlinear systems evolving in discrete time. The problem reduces, after automata-theoretic constructions, to finding the maximal probability of satisfying a parity condition on a (possibly hybrid) state space. While characterizing the exact satisfaction probability is open, we show that a lower bound on this probability can be obtained by (I) computing an under-approximation of the qualitative winning region, i.e., states from which the parity condition can be enforced almost surely, and (II) computing the maximal probability of reaching this qualitative winning region.\r\nThe heart of our approach is a technique to symbolically compute the under-approximation of the qualitative winning region in step (I) via a finite-state abstraction of the original system as a \r\n-player parity game. Our abstraction procedure uses only the support of the probabilistic evolution; it does not use precise numerical transition probabilities. We prove that the winning set in the abstract -player game induces an under-approximation of the qualitative winning region in the original synthesis problem, along with a policy to solve it. By combining these contributions with (a) a symbolic fixpoint algorithm to solve \r\n-player games and (b) existing techniques for reachability policy synthesis in stochastic nonlinear systems, we get an abstraction-based algorithm for finding a lower bound on the maximal satisfaction probability.\r\nWe have implemented the abstraction-based algorithm in Mascot-SDS, where we combined the outlined abstraction step with our tool Genie (Majumdar et al., 2023) that solves \r\n-player parity games (through a reduction to Rabin games) more efficiently than existing algorithms. We evaluated our implementation on the nonlinear model of a perturbed bistable switch from the literature. We show empirically that the lower bound on the winning region computed by our approach is precise, by comparing against an over-approximation of the qualitative winning region. Moreover, our implementation outperforms a recently proposed tool for solving this problem by a large margin.","lang":"eng"}],"external_id":{"arxiv":["2101.00834"],"isi":["001093188100001"]},"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Majumdar","first_name":"Rupak","full_name":"Majumdar, Rupak"},{"first_name":"Kaushik","last_name":"Mallik","orcid":"0000-0001-9864-7475","id":"0834ff3c-6d72-11ec-94e0-b5b0a4fb8598","full_name":"Mallik, Kaushik"},{"last_name":"Schmuck","first_name":"Anne Kathrin","full_name":"Schmuck, Anne Kathrin"},{"first_name":"Sadegh","last_name":"Soudjani","full_name":"Soudjani, Sadegh"}],"volume":51,"citation":{"apa":"Majumdar, R., Mallik, K., Schmuck, A. K., & Soudjani, S. (2024). Symbolic control for stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems. Elsevier. https://doi.org/10.1016/j.nahs.2023.101430","chicago":"Majumdar, Rupak, Kaushik Mallik, Anne Kathrin Schmuck, and Sadegh Soudjani. “Symbolic Control for Stochastic Systems via Finite Parity Games.” Nonlinear Analysis: Hybrid Systems. Elsevier, 2024. https://doi.org/10.1016/j.nahs.2023.101430.","mla":"Majumdar, Rupak, et al. “Symbolic Control for Stochastic Systems via Finite Parity Games.” Nonlinear Analysis: Hybrid Systems, vol. 51, no. 2, 101430, Elsevier, 2024, doi:10.1016/j.nahs.2023.101430.","ieee":"R. Majumdar, K. Mallik, A. K. Schmuck, and S. Soudjani, “Symbolic control for stochastic systems via finite parity games,” Nonlinear Analysis: Hybrid Systems, vol. 51, no. 2. Elsevier, 2024.","short":"R. Majumdar, K. Mallik, A.K. Schmuck, S. Soudjani, Nonlinear Analysis: Hybrid Systems 51 (2024).","ama":"Majumdar R, Mallik K, Schmuck AK, Soudjani S. Symbolic control for stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems. 2024;51(2). doi:10.1016/j.nahs.2023.101430","ista":"Majumdar R, Mallik K, Schmuck AK, Soudjani S. 2024. Symbolic control for stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems. 51(2), 101430."},"project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","grant_number":"101020093","call_identifier":"H2020","name":"Vigilant Algorithmic Monitoring of Software"}],"day":"01","status":"public","ec_funded":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"month":"02","language":[{"iso":"eng"}],"date_published":"2024-02-01T00:00:00Z","arxiv":1,"publisher":"Elsevier","department":[{"_id":"ToHe"}],"date_updated":"2025-04-14T07:55:55Z","isi":1,"oa":1,"file_date_updated":"2024-07-16T10:26:41Z","_id":"14400","scopus_import":"1","article_type":"original","intvolume":" 51","oa_version":"Published Version","acknowledgement":"We thank Daniel Hausmann and Nir Piterman for their valuable comments on an earlier version of the manuscript of our other paper [22] where we present, among other things, the parity fixpoint for 2 1/2-player games (for a slightly more general class of games) with a different and indirect proof of correctness. Based on their comments we observed that, unlike the other fixpoints that we present in [22], the parity fixpoint does not follow the exact same structure as its counterpart for 2-player games, which we also use int his paper.\r\nWe also thank Thejaswini Raghavan for observing that our symbolic parity fixpoint algorithm can be solved in quasi-polynomial time using recent improved algorithms for solving \r\n-calculus expressions. This significantly improved the complexity bounds of our algorithm in this paper.\r\nThe work of R. Majumdar and A.-K. Schmuck are partially supported by DFG, Germany project 389792660 TRR 248–CPEC. A.-K. Schmuck is additionally funded through DFG, Germany project (SCHM 3541/1-1). K. Mallik is supported by the ERC project ERC-2020-AdG 101020093. S. Soudjani is supported by the following projects: EPSRC EP/V043676/1, EIC 101070802, and ERC 101089047.","type":"journal_article"},{"abstract":[{"lang":"eng","text":"We prove that the mesoscopic linear statistics ∑if(na(σi−z0)) of the eigenvalues {σi}i of large n×n non-Hermitian random matrices with complex centred i.i.d. entries are asymptotically Gaussian for any H20-functions f around any point z0 in the bulk of the spectrum on any mesoscopic scale 0Probability Theory and Related Fields. Springer Nature, 2024. https://doi.org/10.1007/s00440-023-01229-1.","apa":"Cipolloni, G., Erdös, L., & Schröder, D. J. (2024). Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. Springer Nature. https://doi.org/10.1007/s00440-023-01229-1","mla":"Cipolloni, Giorgio, et al. “Mesoscopic Central Limit Theorem for Non-Hermitian Random Matrices.” Probability Theory and Related Fields, vol. 188, Springer Nature, 2024, pp. 1131–82, doi:10.1007/s00440-023-01229-1.","short":"G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields 188 (2024) 1131–1182.","ieee":"G. Cipolloni, L. Erdös, and D. J. Schröder, “Mesoscopic central limit theorem for non-Hermitian random matrices,” Probability Theory and Related Fields, vol. 188. Springer Nature, pp. 1131–1182, 2024.","ama":"Cipolloni G, Erdös L, Schröder DJ. Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. 2024;188:1131-1182. doi:10.1007/s00440-023-01229-1","ista":"Cipolloni G, Erdös L, Schröder DJ. 2024. Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. 188, 1131–1182."},"ec_funded":1,"status":"public","day":"01"},{"author":[{"first_name":"Guifang","last_name":"Zeng","full_name":"Zeng, Guifang"},{"full_name":"Sun, Qing","first_name":"Qing","last_name":"Sun"},{"last_name":"Horta","first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","full_name":"Horta, Sharona"},{"full_name":"Wang, Shang","last_name":"Wang","first_name":"Shang"},{"first_name":"Xuan","last_name":"Lu","full_name":"Lu, Xuan"},{"full_name":"Zhang, Chaoyue","first_name":"Chaoyue","last_name":"Zhang"},{"full_name":"Li, Jing","first_name":"Jing","last_name":"Li"},{"first_name":"Junshan","last_name":"Li","full_name":"Li, Junshan"},{"last_name":"Ci","first_name":"Lijie","full_name":"Ci, Lijie"},{"first_name":"Yanhong","last_name":"Tian","full_name":"Tian, Yanhong"},{"full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","first_name":"Maria","last_name":"Ibáñez"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":36,"acknowledged_ssus":[{"_id":"EM-Fac"}],"pmid":1,"article_processing_charge":"No","abstract":[{"lang":"eng","text":"Low‐cost, safe, and environmental‐friendly rechargeable aqueous zinc‐ion batteries (ZIBs) are promising as next‐generation energy storage devices for wearable electronics among other applications. However, sluggish ionic transport kinetics and the unstable electrode structure during ionic insertion/extraction hampers their deployment. Herein,  we propose a new cathode material based on a layered metal chalcogenide (LMC), bismuth telluride (Bi2Te3), coated with polypyrrole (PPy). Taking advantage of the PPy coating, the Bi2Te3@PPy composite presents strong ionic absorption affinity, high oxidation resistance, and high structural stability. The ZIBs based on Bi2Te3@PPy cathodes exhibit high capacities and ultra‐long lifespans of over 5000 cycles. They also present outstanding stability even under bending. In addition,  we analyze here the reaction mechanism using in situ X‐ray diffraction, X‐ray photoelectron spectroscopy, and computational tools and demonstrate that, in the aqueous system, Zn2+ is not inserted into the cathode as previously assumed. In contrast, proton charge storage dominates the process. Overall, this work not only shows the great potential of LMCs as ZIBs cathode materials and the advantages of PPy coating, but also clarifies the charge/discharge mechanism in rechargeable ZIBs based on LMCs."}],"publication_status":"published","external_id":{"pmid":["37555532"],"isi":["001085681000001"]},"title":"A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries","keyword":["Mechanical Engineering","Mechanics of Materials","General Materials Science"],"year":"2024","date_created":"2023-10-17T10:53:56Z","article_number":"2305128","issue":"1","doi":"10.1002/adma.202305128","publication_identifier":{"eissn":["1521-4095"],"issn":["0935-9648"]},"publication":"Advanced Materials","quality_controlled":"1","article_type":"original","oa_version":"None","intvolume":" 36","acknowledgement":"G.Z. and Q.S. contributed equally to this work. This work was supported by the National Natural Science Foundation of China (52105329, 52175300) and the Heilongjiang Provincial Natural Science Foundation of China (LH2022E059). G.Z., X.L., and C.Z. thank the China Scholarship Council (CSC) for the scholarship support. This research was supported by the Scientific Service Units of ISTA through resources provided by the Electron Microscopy Facility. S.H. and M.I. acknowledge funding by ISTA and Werner Siemens.","type":"journal_article","_id":"14435","scopus_import":"1","isi":1,"language":[{"iso":"eng"}],"month":"01","date_published":"2024-01-04T00:00:00Z","publisher":"Wiley","department":[{"_id":"MaIb"}],"date_updated":"2025-04-15T06:36:40Z","day":"04","status":"public","citation":{"mla":"Zeng, Guifang, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” Advanced Materials, vol. 36, no. 1, 2305128, Wiley, 2024, doi:10.1002/adma.202305128.","chicago":"Zeng, Guifang, Qing Sun, Sharona Horta, Shang Wang, Xuan Lu, Chaoyue Zhang, Jing Li, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” Advanced Materials. Wiley, 2024. https://doi.org/10.1002/adma.202305128.","apa":"Zeng, G., Sun, Q., Horta, S., Wang, S., Lu, X., Zhang, C., … Cabot, A. (2024). A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. Wiley. https://doi.org/10.1002/adma.202305128","ista":"Zeng G, Sun Q, Horta S, Wang S, Lu X, Zhang C, Li J, Li J, Ci L, Tian Y, Ibáñez M, Cabot A. 2024. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 36(1), 2305128.","ama":"Zeng G, Sun Q, Horta S, et al. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 2024;36(1). doi:10.1002/adma.202305128","short":"G. Zeng, Q. Sun, S. Horta, S. Wang, X. Lu, C. Zhang, J. Li, J. Li, L. Ci, Y. Tian, M. Ibáñez, A. Cabot, Advanced Materials 36 (2024).","ieee":"G. Zeng et al., “A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries,” Advanced Materials, vol. 36, no. 1. Wiley, 2024."},"project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}]},{"publication":"Plant Growth Regulation","doi":"10.1007/s10725-023-01083-0","publication_identifier":{"eissn":["1573-5087"],"issn":["0167-6903"]},"year":"2024","date_created":"2023-10-22T22:01:15Z","ddc":["580"],"has_accepted_license":"1","quality_controlled":"1","file":[{"file_size":2847929,"date_updated":"2024-07-16T08:13:24Z","checksum":"e63271b1d57c1f03c1d993fd62cba59c","relation":"main_file","access_level":"open_access","file_id":"17252","creator":"dernst","success":1,"file_name":"2024_PlantGrowthReg_Bieleszova.pdf","content_type":"application/pdf","date_created":"2024-07-16T08:13:24Z"}],"volume":102,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Bieleszová","first_name":"Kristýna","full_name":"Bieleszová, Kristýna"},{"last_name":"Hladík","first_name":"Pavel","full_name":"Hladík, Pavel"},{"last_name":"Kubala","first_name":"Martin","full_name":"Kubala, Martin"},{"first_name":"Richard","last_name":"Napier","full_name":"Napier, Richard"},{"full_name":"Brunoni, Federica","last_name":"Brunoni","first_name":"Federica"},{"last_name":"Gelová","first_name":"Zuzana","id":"0AE74790-0E0B-11E9-ABC7-1ACFE5697425","orcid":"0000-0003-4783-1752","full_name":"Gelová, Zuzana"},{"last_name":"Fiedler","first_name":"Lukas","full_name":"Fiedler, Lukas","id":"7c417475-8972-11ed-ae7b-8b674ca26986"},{"full_name":"Kulich, Ivan","id":"57a1567c-8314-11eb-9063-c9ddc3451a54","last_name":"Kulich","first_name":"Ivan"},{"first_name":"Miroslav","last_name":"Strnad","full_name":"Strnad, Miroslav"},{"last_name":"Doležal","first_name":"Karel","full_name":"Doležal, Karel"},{"first_name":"Ondřej","last_name":"Novák","full_name":"Novák, Ondřej"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","first_name":"Jiří","last_name":"Friml"},{"full_name":"Žukauskaitė, Asta","last_name":"Žukauskaitė","first_name":"Asta"}],"title":"New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana","abstract":[{"text":"Auxin belongs among major phytohormones and governs multiple aspects of plant growth and development. The establishment of auxin concentration gradients, determines, among other processes, plant organ positioning and growth responses to environmental stimuli.\r\nHerein we report the synthesis of new NBD- or DNS-labelled IAA derivatives and the elucidation of their biological activity, fluorescence properties and subcellular accumulation patterns in planta. These novel compounds did not show auxin-like activity, but instead antagonized physiological auxin effects. The DNS-labelled derivatives FL5 and FL6 showed strong anti-auxin activity in roots and hypocotyls, which also occurred at the level of gene transcription as confirmed by quantitative PCR analysis. The auxin antagonism of our derivatives was further demonstrated in vitro using an SPR-based binding assay. The NBD-labelled compound FL4 with the best fluorescence properties proved to be unsuitable to study auxin accumulation patterns in planta. On the other hand, the strongest anti-auxin activity possessing compounds FL5 and FL6 could be useful to study binding mechanisms to auxin receptors and for manipulations of auxin-regulated processes.","lang":"eng"}],"publication_status":"published","external_id":{"isi":["001084334300001"]},"page":"589-602","article_processing_charge":"Yes (via OA deal)","day":"01","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"citation":{"ama":"Bieleszová K, Hladík P, Kubala M, et al. New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. 2024;102:589-602. doi:10.1007/s10725-023-01083-0","ista":"Bieleszová K, Hladík P, Kubala M, Napier R, Brunoni F, Gelová Z, Fiedler L, Kulich I, Strnad M, Doležal K, Novák O, Friml J, Žukauskaitė A. 2024. New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. 102, 589–602.","ieee":"K. Bieleszová et al., “New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana,” Plant Growth Regulation, vol. 102. Springer Nature, pp. 589–602, 2024.","short":"K. Bieleszová, P. Hladík, M. Kubala, R. Napier, F. Brunoni, Z. Gelová, L. Fiedler, I. Kulich, M. Strnad, K. Doležal, O. Novák, J. Friml, A. Žukauskaitė, Plant Growth Regulation 102 (2024) 589–602.","mla":"Bieleszová, Kristýna, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation, vol. 102, Springer Nature, 2024, pp. 589–602, doi:10.1007/s10725-023-01083-0.","apa":"Bieleszová, K., Hladík, P., Kubala, M., Napier, R., Brunoni, F., Gelová, Z., … Žukauskaitė, A. (2024). New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. Springer Nature. https://doi.org/10.1007/s10725-023-01083-0","chicago":"Bieleszová, Kristýna, Pavel Hladík, Martin Kubala, Richard Napier, Federica Brunoni, Zuzana Gelová, Lukas Fiedler, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation. Springer Nature, 2024. https://doi.org/10.1007/s10725-023-01083-0."},"_id":"14447","scopus_import":"1","acknowledgement":"The authors would like to thank Karolína Kubiasová and Iñigo Saiz-Fernández for valuable scientific discussions. Open access publishing supported by the National Technical Library in Prague. This work was supported by the Palacký University Olomouc Young Researcher Grant Competition (JG_2020_002), by the Internal Grant Agency of Palacký University Olomouc (IGA_PrF_2023_016, IGA_PrF_2023_031), by the Ministry of Education, Youth and Sports of the Czech Republic through the European Regional Development Fund-Project Plants as a tool for sustainable global development (CZ.02.1.01/0.0/0.0/16_019/0000827) and the project Support of mobility at Palacký University Olomouc II. (CZ.02.2.69/0.0/0.0/18_053/0016919). The Biacore T200 SPR instrument was provided by the WISB Research Technology Facility within the School of Life Sciences, University of Warwick.","type":"journal_article","article_type":"original","oa_version":"Published Version","intvolume":" 102","department":[{"_id":"JiFr"}],"publisher":"Springer Nature","date_updated":"2024-07-16T08:13:39Z","language":[{"iso":"eng"}],"month":"04","date_published":"2024-04-01T00:00:00Z","oa":1,"file_date_updated":"2024-07-16T08:13:24Z","isi":1},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"ec_funded":1,"day":"01","status":"public","citation":{"apa":"Cornalba, F., Disselkamp, C., Scassola, D., & Helf, C. (2024). Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. Springer Nature. https://doi.org/10.1007/s00521-023-09033-7","chicago":"Cornalba, Federico, Constantin Disselkamp, Davide Scassola, and Christopher Helf. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.” Neural Computing and Applications. Springer Nature, 2024. https://doi.org/10.1007/s00521-023-09033-7.","mla":"Cornalba, Federico, et al. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.” Neural Computing and Applications, vol. 36, no. 2, Springer Nature, 2024, pp. 617–37, doi:10.1007/s00521-023-09033-7.","ieee":"F. Cornalba, C. Disselkamp, D. Scassola, and C. Helf, “Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading,” Neural Computing and Applications, vol. 36, no. 2. Springer Nature, pp. 617–637, 2024.","short":"F. Cornalba, C. Disselkamp, D. Scassola, C. Helf, Neural Computing and Applications 36 (2024) 617–637.","ama":"Cornalba F, Disselkamp C, Scassola D, Helf C. Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. 2024;36(2):617-637. doi:10.1007/s00521-023-09033-7","ista":"Cornalba F, Disselkamp C, Scassola D, Helf C. 2024. Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. 36(2), 617–637."},"project":[{"grant_number":"F6504","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships"}],"intvolume":" 36","oa_version":"Published Version","article_type":"original","type":"journal_article","acknowledgement":"Open access funding provided by Università degli Studi di Trieste within the CRUI-CARE Agreement. Funding was provided by Austrian Science Fund (Grant No. F65), Horizon 2020 (Grant No. 754411) and Österreichische Forschungsförderungsgesellschaft.","scopus_import":"1","_id":"14451","file_date_updated":"2024-07-16T08:08:54Z","oa":1,"date_published":"2024-01-01T00:00:00Z","language":[{"iso":"eng"}],"month":"01","date_updated":"2025-04-23T07:39:14Z","publisher":"Springer Nature","department":[{"_id":"JuFi"}],"arxiv":1,"date_created":"2023-10-22T22:01:16Z","year":"2024","publication_identifier":{"issn":["0941-0643"],"eissn":["1433-3058"]},"doi":"10.1007/s00521-023-09033-7","issue":"2","publication":"Neural Computing and Applications","corr_author":"1","file":[{"file_id":"17251","access_level":"open_access","checksum":"04573d8e74c6119b97c2ca0a984e19a1","relation":"main_file","file_size":4412285,"date_updated":"2024-07-16T08:08:54Z","date_created":"2024-07-16T08:08:54Z","content_type":"application/pdf","file_name":"2024_NeuralCompApplications_Cornalba.pdf","success":1,"creator":"dernst"}],"quality_controlled":"1","has_accepted_license":"1","ddc":["000"],"author":[{"full_name":"Cornalba, Federico","orcid":"0000-0002-6269-5149","id":"2CEB641C-A400-11E9-A717-D712E6697425","last_name":"Cornalba","first_name":"Federico"},{"full_name":"Disselkamp, Constantin","first_name":"Constantin","last_name":"Disselkamp"},{"last_name":"Scassola","first_name":"Davide","full_name":"Scassola, Davide"},{"first_name":"Christopher","last_name":"Helf","full_name":"Helf, Christopher"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":36,"pmid":1,"article_processing_charge":"Yes (via OA deal)","page":"617-637","publication_status":"published","external_id":{"arxiv":["2203.04579"],"pmid":["38187995"]},"abstract":[{"text":"We investigate the potential of Multi-Objective, Deep Reinforcement Learning for stock and cryptocurrency single-asset trading: in particular, we consider a Multi-Objective algorithm which generalizes the reward functions and discount factor (i.e., these components are not specified a priori, but incorporated in the learning process). Firstly, using several important assets (BTCUSD, ETHUSDT, XRPUSDT, AAPL, SPY, NIFTY50), we verify the reward generalization property of the proposed Multi-Objective algorithm, and provide preliminary statistical evidence showing increased predictive stability over the corresponding Single-Objective strategy. Secondly, we show that the Multi-Objective algorithm has a clear edge over the corresponding Single-Objective strategy when the reward mechanism is sparse (i.e., when non-null feedback is infrequent over time). Finally, we discuss the generalization properties with respect to the discount factor. The entirety of our code is provided in open-source format.","lang":"eng"}],"title":"Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading"},{"isi":1,"oa":1,"file_date_updated":"2025-01-09T07:52:12Z","language":[{"iso":"eng"}],"month":"12","date_published":"2024-12-01T00:00:00Z","department":[{"_id":"NiBa"}],"publisher":"Wiley","date_updated":"2025-01-09T07:53:18Z","article_type":"original","oa_version":"Published Version","intvolume":" 33","acknowledgement":"We would like to thank members of the Littorina team for their advice and feedback during this project. In particular, we thank Alan Le Moan, who inspired us to look at heterozygosity differences to identify inversions, and Katherine Hearn for helping with the PCA scripts. We thank Edinburgh Genomics for library preparation and sequencing. Sample collections, sequencing and data preparation were supported by the European Research Council (ERC-2015-AdG-693030- BARRIERS) and the Natural Environment Research Council (NE/P001610/1). The analysis was supported by the Swedish Research Council (vetenskaprådet; 2018-03695_VR) and the Portuguese Foundation for Science and Technology (Fundación para a Ciência e Tecnologia) through a research project (PTDC/BIA-EVL/1614/2021) and CEEC contract (2020.00275.CEECIND).","type":"journal_article","_id":"14463","scopus_import":"1","citation":{"apa":"Reeve, J., Butlin, R. K., Koch, E. L., Stankowski, S., & Faria, R. (2024). Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. Wiley. https://doi.org/10.1111/mec.17160","chicago":"Reeve, James, Roger K. Butlin, Eva L. Koch, Sean Stankowski, and Rui Faria. “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology. Wiley, 2024. https://doi.org/10.1111/mec.17160.","mla":"Reeve, James, et al. “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology, vol. 33, no. 24, e17160, Wiley, 2024, doi:10.1111/mec.17160.","ieee":"J. Reeve, R. K. Butlin, E. L. Koch, S. Stankowski, and R. Faria, “Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana),” Molecular Ecology, vol. 33, no. 24. Wiley, 2024.","short":"J. Reeve, R.K. Butlin, E.L. Koch, S. Stankowski, R. Faria, Molecular Ecology 33 (2024).","ama":"Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. 2024;33(24). doi:10.1111/mec.17160","ista":"Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. 2024. Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. 33(24), e17160."},"OA_type":"hybrid","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"day":"01","status":"public","article_processing_charge":"Yes (in subscription journal)","abstract":[{"text":"Inversions are thought to play a key role in adaptation and speciation, suppressing recombination between diverging populations. Genes influencing adaptive traits cluster in inversions, and changes in inversion frequencies are associated with environmental differences. However, in many organisms, it is unclear if inversions are geographically and taxonomically widespread. The intertidal snail, Littorina saxatilis, is one such example. Strong associations between putative polymorphic inversions and phenotypic differences have been demonstrated between two ecotypes of L. saxatilis in Sweden and inferred elsewhere, but no direct evidence for inversion polymorphism currently exists across the species range. Using whole genome data from 107 snails, most inversion polymorphisms were found to be widespread across the species range. The frequencies of some inversion arrangements were significantly different among ecotypes, suggesting a parallel adaptive role. Many inversions were also polymorphic in the sister species, L. arcana, hinting at an ancient origin.","lang":"eng"}],"external_id":{"isi":["001085119000001"],"pmid":["37843465"]},"publication_status":"published","title":"Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana)","author":[{"full_name":"Reeve, James","first_name":"James","last_name":"Reeve"},{"full_name":"Butlin, Roger K.","first_name":"Roger K.","last_name":"Butlin"},{"full_name":"Koch, Eva L.","last_name":"Koch","first_name":"Eva L."},{"last_name":"Stankowski","first_name":"Sean","full_name":"Stankowski, Sean","id":"43161670-5719-11EA-8025-FABC3DDC885E"},{"full_name":"Faria, Rui","first_name":"Rui","last_name":"Faria"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":33,"OA_place":"publisher","pmid":1,"file":[{"date_updated":"2025-01-09T07:52:12Z","file_size":6228700,"checksum":"686576036663f489c2d079df3079d126","relation":"main_file","access_level":"open_access","file_id":"18785","creator":"dernst","success":1,"file_name":"2024_MolecularEcology_Reeve.pdf","content_type":"application/pdf","date_created":"2025-01-09T07:52:12Z"}],"quality_controlled":"1","has_accepted_license":"1","ddc":["570"],"year":"2024","date_created":"2023-10-29T23:01:17Z","article_number":"e17160","issue":"24","publication_identifier":{"eissn":["1365-294X"],"issn":["0962-1083"]},"doi":"10.1111/mec.17160","publication":"Molecular Ecology"},{"doi":"10.1073/pnas.2316284121","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"issue":"11","APC_amount":"3040,36 EUR","publication":"Proceedings of the National Academy of Sciences of the United States of America","date_created":"2023-10-31T13:30:00Z","year":"2024","article_number":"e2316284121","has_accepted_license":"1","ddc":["570"],"corr_author":"1","file":[{"success":1,"creator":"dernst","content_type":"application/pdf","file_name":"2024_PNAS_Habig.pdf","date_created":"2024-03-19T09:02:57Z","file_size":5750361,"date_updated":"2024-03-19T09:02:57Z","access_level":"open_access","checksum":"f5e871db617b682edc71fcd08670dc81","relation":"main_file","file_id":"15124"}],"quality_controlled":"1","pmid":1,"author":[{"last_name":"Habig","first_name":"Michael","full_name":"Habig, Michael"},{"full_name":"Grasse, Anna V","id":"406F989C-F248-11E8-B48F-1D18A9856A87","first_name":"Anna V","last_name":"Grasse"},{"full_name":"Müller, Judith","first_name":"Judith","last_name":"Müller"},{"first_name":"Eva H.","last_name":"Stukenbrock","full_name":"Stukenbrock, Eva H."},{"full_name":"Leitner, Hanna","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7","last_name":"Leitner","first_name":"Hanna"},{"full_name":"Cremer, Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2193-3868","last_name":"Cremer","first_name":"Sylvia"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":121,"OA_place":"publisher","title":"Frequent horizontal chromosome transfer between asexual fungal insect pathogens","article_processing_charge":"Yes (in subscription journal)","external_id":{"pmid":["38442176"],"isi":["001207630200005"]},"publication_status":"published","abstract":[{"lang":"eng","text":"Entire chromosomes are typically only transmitted vertically from one generation to the next. The horizontal transfer of such chromosomes has long been considered improbable, yet gained recent support in several pathogenic fungi where it may affect the fitness or host specificity. To date, it is unknown how these transfers occur, how common they are and whether they can occur between different species. In this study, we show multiple independent instances of horizontal transfers of the same accessory chromosome between two distinct strains of the asexual entomopathogenic fungusMetarhizium robertsiiduring experimental co-infection of its insect host, the Argentine ant. Notably, only the one chromosome – but no other – was transferred from the donor to the recipient strain. The recipient strain, now harboring the accessory chromosome, exhibited a competitive advantage under certain host conditions. By phylogenetic analysis we further demonstrate that the same accessory chromosome was horizontally transferred in a natural environment betweenM. robertsiiand another congeneric insect pathogen,M. guizhouense. Hence horizontal chromosome transfer is not limited to the observed frequent events within species during experimental infections but also occurs naturally across species. The transferred accessory chromosome contains genes that might be involved in its preferential horizontal transfer, encoding putative histones and histone-modifying enzymes, but also putative virulence factors that may support its establishment. Our study reveals that both intra- and interspecies horizontal transfer of entire chromosomes is more frequent than previously assumed, likely representing a not uncommon mechanism for gene exchange.Significance StatementThe enormous success of bacterial pathogens has been attributed to their ability to exchange genetic material between one another. Similarly, in eukaryotes, horizontal transfer of genetic material allowed the spread of virulence factors across species. The horizontal transfer of whole chromosomes could be an important pathway for such exchange of genetic material, but little is known about the origin of transferable chromosomes and how frequently they are exchanged. Here, we show that the transfer of accessory chromosomes - chromosomes that are non-essential but may provide fitness benefits - is common during fungal co-infections and is even possible between distant pathogenic species, highlighting the importance of horizontal gene transfer via chromosome transfer also for the evolution and function of eukaryotic pathogens."}],"status":"public","day":"12","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"OA_type":"hybrid","ec_funded":1,"citation":{"ieee":"M. Habig, A. V. Grasse, J. Müller, E. H. Stukenbrock, H. Leitner, and S. Cremer, “Frequent horizontal chromosome transfer between asexual fungal insect pathogens,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 11. National Academy of Sciences, 2024.","short":"M. Habig, A.V. Grasse, J. Müller, E.H. Stukenbrock, H. Leitner, S. Cremer, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","ista":"Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. 2024. Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. 121(11), e2316284121.","ama":"Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(11). doi:10.1073/pnas.2316284121","apa":"Habig, M., Grasse, A. V., Müller, J., Stukenbrock, E. H., Leitner, H., & Cremer, S. (2024). Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2316284121","chicago":"Habig, Michael, Anna V Grasse, Judith Müller, Eva H. Stukenbrock, Hanna Leitner, and Sylvia Cremer. “Frequent Horizontal Chromosome Transfer between Asexual Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2316284121.","mla":"Habig, Michael, et al. “Frequent Horizontal Chromosome Transfer between Asexual Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 11, e2316284121, National Academy of Sciences, 2024, doi:10.1073/pnas.2316284121."},"project":[{"_id":"2649B4DE-B435-11E9-9278-68D0E5697425","grant_number":"771402","call_identifier":"H2020","name":"Epidemics in ant societies on a chip"}],"scopus_import":"1","_id":"14478","intvolume":" 121","oa_version":"Published Version","article_type":"original","acknowledgement":"We thank Bernhardt Steinwender, Jorgen Eilenberg, and Nicolai V. Meyling for the fungal strains. We further thank Chengshu Wang for providing the short sequencing reads for M. guizhouense ARESF977 he used for his published genome assembly, and Kristian Ullrich for help in the bioinformatics analysis for methylation pattern in Nanopore reads, and the VBC and the Max Planck Society for the use of their sequencing centers. We thank Barbara Milutinović and Hinrich Schulenburg for discussion, and Tal Dagan and Jens Rolff for comments on a previous version of the manuscript. Fig. 1A was created with BioRender.com. This study received funding by the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (No. 771402; EPIDEMICSonCHIP) to S.C. and by the German Research Foundation (DFG grant HA9263/1-1) to M.H.","type":"journal_article","date_published":"2024-03-12T00:00:00Z","language":[{"iso":"eng"}],"month":"03","date_updated":"2025-08-05T13:30:51Z","publisher":"National Academy of Sciences","department":[{"_id":"SyCr"}],"isi":1,"file_date_updated":"2024-03-19T09:02:57Z","oa":1},{"article_processing_charge":"No","page":"902-909.e6","publication_status":"published","external_id":{"isi":["001195884300001"],"pmid":["38307022"]},"abstract":[{"lang":"eng","text":"In animals, parasitic infections impose significant fitness costs.1,2,3,4,5,6 Infected animals can alter their feeding behavior to resist infection,7,8,9,10,11,12 but parasites can manipulate animal foraging behavior to their own benefits.13,14,15,16 How nutrition influences host-parasite interactions is not well understood, as studies have mainly focused on the host and less on the parasite.9,12,17,18,19,20,21,22,23 We used the nutritional geometry framework24 to investigate the role of amino acids (AA) and carbohydrates (C) in a host-parasite system: the Argentine ant, Linepithema humile, and the entomopathogenic fungus, Metarhizium brunneum. First, using 18 diets varying in AA:C composition, we established that the fungus performed best on the high-amino-acid diet 1:4. Second, we found that the fungus reached this optimal diet when given various diet pairings, revealing its ability to cope with nutritional challenges. Third, we showed that the optimal fungal diet reduced the lifespan of healthy ants when compared with a high-carbohydrate diet but had no effect on infected ants. Fourth, we revealed that infected ant colonies, given a choice between the optimal fungal diet and a high-carbohydrate diet, chose the optimal fungal diet, whereas healthy colonies avoided it. Lastly, by disentangling fungal infection from host immune response, we demonstrated that infected ants foraged on the optimal fungal diet in response to immune activation and not as a result of parasite manipulation. Therefore, we revealed that infected ant colonies chose a diet that is costly for survival in the long term but beneficial in the short term—a form of collective self-medication."}],"title":"Fungal infection alters collective nutritional intake of ant colonies","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Csata, Eniko","first_name":"Eniko","last_name":"Csata"},{"full_name":"Perez-Escudero, Alfonso","last_name":"Perez-Escudero","first_name":"Alfonso"},{"first_name":"Emmanuel","last_name":"Laury","full_name":"Laury, Emmanuel"},{"last_name":"Leitner","first_name":"Hanna","full_name":"Leitner, Hanna","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7"},{"full_name":"Latil, Gerard","first_name":"Gerard","last_name":"Latil"},{"last_name":"Heinze","first_name":"Juerge","full_name":"Heinze, Juerge"},{"last_name":"Simpson","first_name":"Stephen","full_name":"Simpson, Stephen"},{"last_name":"Cremer","first_name":"Sylvia","full_name":"Cremer, Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2193-3868"},{"last_name":"Dussutour","first_name":"Audrey","full_name":"Dussutour, Audrey"}],"volume":34,"pmid":1,"quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2023.10.26.564092"}],"date_created":"2023-10-31T13:30:20Z","year":"2024","doi":"10.1016/j.cub.2024.01.017","publication_identifier":{"eissn":["1879-0445"],"issn":["0960-9822"]},"issue":"4","publication":"Current Biology","isi":1,"oa":1,"date_published":"2024-02-26T00:00:00Z","language":[{"iso":"eng"}],"month":"02","date_updated":"2025-08-05T13:29:38Z","department":[{"_id":"SyCr"}],"publisher":"Elsevier","intvolume":" 34","oa_version":"Preprint","article_type":"original","type":"journal_article","acknowledgement":"We are sincerely grateful to the referees for their valuable comments and suggestions, which helped us to improve the paper. We are thankful to Jorgen Eilenberg and Nicolai V. Meyling for the fungal strain, to Simon Tragust, Abel Bernadou, and Brian Lazarro for insightful discussions, to Iago Sanmartín-Villar, Léa Briard, Céline Maitrel, and Nolwenn Rissen for their help with the experiments. Furthermore, we thank Anna V. Grasse for help with the immune gene expression analyses. We thank Sergio Ibarra for creating the graphical abstract. E.C. was supported by a Fyssen Foundation grant and the Alexander von Humboldt Foundation. A.D. was supported by the CNRS.","scopus_import":"1","_id":"14479","citation":{"ieee":"E. Csata et al., “Fungal infection alters collective nutritional intake of ant colonies,” Current Biology, vol. 34, no. 4. Elsevier, p. 902–909.e6, 2024.","short":"E. Csata, A. Perez-Escudero, E. Laury, H. Leitner, G. Latil, J. Heinze, S. Simpson, S. Cremer, A. Dussutour, Current Biology 34 (2024) 902–909.e6.","ista":"Csata E, Perez-Escudero A, Laury E, Leitner H, Latil G, Heinze J, Simpson S, Cremer S, Dussutour A. 2024. Fungal infection alters collective nutritional intake of ant colonies. Current Biology. 34(4), 902–909.e6.","ama":"Csata E, Perez-Escudero A, Laury E, et al. Fungal infection alters collective nutritional intake of ant colonies. Current Biology. 2024;34(4):902-909.e6. doi:10.1016/j.cub.2024.01.017","chicago":"Csata, Eniko, Alfonso Perez-Escudero, Emmanuel Laury, Hanna Leitner, Gerard Latil, Juerge Heinze, Stephen Simpson, Sylvia Cremer, and Audrey Dussutour. “Fungal Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology. Elsevier, 2024. https://doi.org/10.1016/j.cub.2024.01.017.","apa":"Csata, E., Perez-Escudero, A., Laury, E., Leitner, H., Latil, G., Heinze, J., … Dussutour, A. (2024). Fungal infection alters collective nutritional intake of ant colonies. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2024.01.017","mla":"Csata, Eniko, et al. “Fungal Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology, vol. 34, no. 4, Elsevier, 2024, p. 902–909.e6, doi:10.1016/j.cub.2024.01.017."},"day":"26","status":"public"}]