[{"file":[{"creator":"gtkacik","date_created":"2025-05-08T05:41:31Z","date_updated":"2025-05-08T05:41:31Z","file_name":"pre_tasep_export_data.zip","success":1,"file_size":7387217,"content_type":"application/zip","file_id":"19659","checksum":"5c15966e4139f10281ab03575f753f82","access_level":"open_access","relation":"main_file"},{"checksum":"939a9341feee946a2399cab226fe69e8","content_type":"text/plain","file_id":"19678","relation":"main_file","access_level":"open_access","date_created":"2025-05-12T07:36:23Z","date_updated":"2025-05-12T07:36:23Z","creator":"gtkacik","file_size":587,"file_name":"readme.txt"}],"abstract":[{"text":"We consider a family of totally asymmetric simple exclusion processes (TASEPs), consisting of particles on a lattice that require binding by a \"token\" in various physical configurations to advance over the lattice. Using a combination of theory and simulations, we address the following questions: (i) How token binding kinetics affects the current-density relation on the lattice; (ii) How this current-density relation depends on the scarcity of tokens; (iii) How tokens propagate the effects of the locally-imposed disorder (such as a slow site) over the entire lattice; (iv) How a shared pool of tokens couples concurrent TASEPs running on multiple lattices; (v) How our results translate to TASEPs with open boundaries that exchange particles with the reservoir. Since real particle motion (including in biological systems that inspired the standard TASEP model, e.g., protein synthesis or movement of molecular motors) is often catalyzed, regulated, actuated, or otherwise mediated, the token-driven TASEP dynamics analyzed in this paper should allow for a better understanding of real systems and enable a closer match between TASEP theory and experimental observations.","lang":"eng"}],"corr_author":"1","oa_version":"Published Version","year":"2025","department":[{"_id":"GaTk"}],"_id":"19658","contributor":[{"last_name":"Kavcic","id":"350F91D2-F248-11E8-B48F-1D18A9856A87","contributor_type":"researcher","first_name":"Bor","orcid":"0000-0001-6041-254X"}],"article_processing_charge":"No","related_material":{"record":[{"id":"19785","relation":"used_in_publication","status":"public"}]},"status":"public","date_updated":"2025-09-30T12:44:54Z","has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"oa":1,"day":"08","OA_type":"gold","fulldoi":"https://doi.org/10.15479/AT:ISTA:19658","file_date_updated":"2025-05-12T07:36:23Z","date_published":"2025-05-08T00:00:00Z","OA_place":"publisher","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)"},"type":"research_data","author":[{"full_name":"Tkačik, Gašper","first_name":"Gašper","orcid":"0000-0002-6699-1455","last_name":"Tkačik","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87"}],"month":"05","date_created":"2025-05-08T05:43:38Z","citation":{"chicago":"Tkačik, Gašper. “Token-Driven Totally Asymmetric Simple Exclusion Processes.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT:ISTA:19658\">https://doi.org/10.15479/AT:ISTA:19658</a>.","short":"G. Tkačik, (2025).","ista":"Tkačik G. 2025. Token-driven totally asymmetric simple exclusion processes, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:19658\">10.15479/AT:ISTA:19658</a>.","apa":"Tkačik, G. (2025). Token-driven totally asymmetric simple exclusion processes. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:19658\">https://doi.org/10.15479/AT:ISTA:19658</a>","ama":"Tkačik G. Token-driven totally asymmetric simple exclusion processes. 2025. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:19658\">10.15479/AT:ISTA:19658</a>","mla":"Tkačik, Gašper. <i>Token-Driven Totally Asymmetric Simple Exclusion Processes</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:19658\">10.15479/AT:ISTA:19658</a>.","ieee":"G. Tkačik, “Token-driven totally asymmetric simple exclusion processes.” Institute of Science and Technology Austria, 2025."},"doi":"10.15479/AT:ISTA:19658","title":"Token-driven totally asymmetric simple exclusion processes","license":"https://creativecommons.org/licenses/by-sa/4.0/"},{"ddc":["530"],"oa":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"The author would like to thank Ulrich Linden for introducing him to the Fermi polaron and for his valuable contributions in the early stages of this project. Additionally, the author is grateful to Krzysztof Myśliwy for helpful comments. Open access funding provided by Institute of Science and Technology (IST Austria).","publisher":"Springer Nature","has_accepted_license":"1","intvolume":"       249","department":[{"_id":"RoSe"}],"status":"public","date_updated":"2025-09-30T12:25:19Z","article_processing_charge":"Yes (via OA deal)","_id":"19660","abstract":[{"lang":"eng","text":"We analyze the ground state energy of N fermions in a two-dimensional box interacting with an impurity particle via two-body point interactions. We show that for weak coupling, the ground state energy is asymptotically described by the polaron energy, as proposed by F. Chevy in the physics literature. The polaron energy is the solution of a nonlinear equation involving the Green’s function of the free Fermi gas and the binding energy of the two-body point interaction. We provide quantitative error estimates that are uniform in the thermodynamic limit."}],"corr_author":"1","file":[{"date_created":"2025-05-12T07:27:28Z","date_updated":"2025-05-12T07:27:28Z","creator":"dernst","file_name":"2025_ArchiveRatioMechanics_Mitrouskas.pdf","file_size":886318,"success":1,"checksum":"3606ebd34d59d03f8c66a3a1794c3e4f","content_type":"application/pdf","file_id":"19676","relation":"main_file","access_level":"open_access"}],"isi":1,"external_id":{"isi":["001482770500001"]},"volume":249,"year":"2025","oa_version":"Published Version","language":[{"iso":"eng"}],"quality_controlled":"1","issue":"3","doi":"10.1007/s00205-025-02098-9","publication_identifier":{"eissn":["1432-0673"],"issn":["0003-9527"]},"citation":{"ieee":"D. J. Mitrouskas, “The weakly coupled two-dimensional Fermi polaron,” <i>Archive for Rational Mechanics and Analysis</i>, vol. 249, no. 3. Springer Nature, 2025.","mla":"Mitrouskas, David Johannes. “The Weakly Coupled Two-Dimensional Fermi Polaron.” <i>Archive for Rational Mechanics and Analysis</i>, vol. 249, no. 3, 30, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s00205-025-02098-9\">10.1007/s00205-025-02098-9</a>.","ama":"Mitrouskas DJ. The weakly coupled two-dimensional Fermi polaron. <i>Archive for Rational Mechanics and Analysis</i>. 2025;249(3). doi:<a href=\"https://doi.org/10.1007/s00205-025-02098-9\">10.1007/s00205-025-02098-9</a>","ista":"Mitrouskas DJ. 2025. The weakly coupled two-dimensional Fermi polaron. Archive for Rational Mechanics and Analysis. 249(3), 30.","apa":"Mitrouskas, D. J. (2025). The weakly coupled two-dimensional Fermi polaron. <i>Archive for Rational Mechanics and Analysis</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00205-025-02098-9\">https://doi.org/10.1007/s00205-025-02098-9</a>","short":"D.J. Mitrouskas, Archive for Rational Mechanics and Analysis 249 (2025).","chicago":"Mitrouskas, David Johannes. “The Weakly Coupled Two-Dimensional Fermi Polaron.” <i>Archive for Rational Mechanics and Analysis</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00205-025-02098-9\">https://doi.org/10.1007/s00205-025-02098-9</a>."},"publication":"Archive for Rational Mechanics and Analysis","license":"https://creativecommons.org/licenses/by/4.0/","title":"The weakly coupled two-dimensional Fermi polaron","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","date_created":"2025-05-11T22:02:37Z","article_number":"30","month":"06","author":[{"full_name":"Mitrouskas, David Johannes","first_name":"David Johannes","id":"cbddacee-2b11-11eb-a02e-a2e14d04e52d","last_name":"Mitrouskas"}],"scopus_import":"1","file_date_updated":"2025-05-12T07:27:28Z","date_published":"2025-06-01T00:00:00Z","publication_status":"published","article_type":"original","fulldoi":"https://doi.org/10.1007/s00205-025-02098-9","day":"01","OA_type":"hybrid","OA_place":"publisher"},{"OA_place":"publisher","day":"28","OA_type":"hybrid","fulldoi":"https://doi.org/10.1088/1751-8121/adcdd9","date_published":"2025-04-28T00:00:00Z","article_type":"original","publication_status":"published","file_date_updated":"2025-05-12T07:13:07Z","scopus_import":"1","author":[{"first_name":"Esteban","last_name":"Cárdenas","full_name":"Cárdenas, Esteban"},{"full_name":"Mitrouskas, David Johannes","last_name":"Mitrouskas","id":"cbddacee-2b11-11eb-a02e-a2e14d04e52d","first_name":"David Johannes"}],"article_number":"175201","month":"04","date_created":"2025-05-11T22:02:37Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","title":"The renormalized Nelson model in the weak coupling limit","publication":"Journal of Physics A: Mathematical and Theoretical","publication_identifier":{"eissn":["1751-8121"],"issn":["1751-8113"]},"citation":{"mla":"Cárdenas, Esteban, and David Johannes Mitrouskas. “The Renormalized Nelson Model in the Weak Coupling Limit.” <i>Journal of Physics A: Mathematical and Theoretical</i>, vol. 58, no. 17, 175201, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.1088/1751-8121/adcdd9\">10.1088/1751-8121/adcdd9</a>.","ama":"Cárdenas E, Mitrouskas DJ. The renormalized Nelson model in the weak coupling limit. <i>Journal of Physics A: Mathematical and Theoretical</i>. 2025;58(17). doi:<a href=\"https://doi.org/10.1088/1751-8121/adcdd9\">10.1088/1751-8121/adcdd9</a>","apa":"Cárdenas, E., &#38; Mitrouskas, D. J. (2025). The renormalized Nelson model in the weak coupling limit. <i>Journal of Physics A: Mathematical and Theoretical</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1751-8121/adcdd9\">https://doi.org/10.1088/1751-8121/adcdd9</a>","ista":"Cárdenas E, Mitrouskas DJ. 2025. The renormalized Nelson model in the weak coupling limit. Journal of Physics A: Mathematical and Theoretical. 58(17), 175201.","ieee":"E. Cárdenas and D. J. Mitrouskas, “The renormalized Nelson model in the weak coupling limit,” <i>Journal of Physics A: Mathematical and Theoretical</i>, vol. 58, no. 17. IOP Publishing, 2025.","chicago":"Cárdenas, Esteban, and David Johannes Mitrouskas. “The Renormalized Nelson Model in the Weak Coupling Limit.” <i>Journal of Physics A: Mathematical and Theoretical</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.1088/1751-8121/adcdd9\">https://doi.org/10.1088/1751-8121/adcdd9</a>.","short":"E. Cárdenas, D.J. Mitrouskas, Journal of Physics A: Mathematical and Theoretical 58 (2025)."},"arxiv":1,"doi":"10.1088/1751-8121/adcdd9","issue":"17","quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Published Version","year":"2025","volume":58,"external_id":{"arxiv":["2412.01670"],"isi":["001474094200001"]},"isi":1,"file":[{"file_name":"2025_JourPhysicsA_Cardenas.pdf","file_size":551190,"success":1,"date_created":"2025-05-12T07:13:07Z","date_updated":"2025-05-12T07:13:07Z","creator":"dernst","relation":"main_file","access_level":"open_access","checksum":"a181e1c2d8df08eb683a355e81c5e85a","content_type":"application/pdf","file_id":"19675"}],"corr_author":"1","abstract":[{"text":"The Nelson model describes non-relativistic particles coupled to a relativistic Bose scalar field. In this article, we study the renormalized version of the Nelson model with massless bosons in Davies' weak coupling limit. Our main result states that the two-body Coulomb potential emerges as an effective pair interaction between the particles, which arises from the exchange of virtual excitations of the quantum field.","lang":"eng"}],"_id":"19661","article_processing_charge":"Yes (in subscription journal)","status":"public","date_updated":"2025-09-30T12:24:45Z","department":[{"_id":"RoSe"}],"intvolume":"        58","has_accepted_license":"1","publisher":"IOP Publishing","acknowledgement":"D M thanks Nataˇsa Pavlovi´c for the invitation to the University of Texas at Austin and for the\r\nhospitality offered by the department, where part of this work was performed. E C gratefully\r\nacknowledges support from NSF under Grant Nos DMS-2009549 and DMS-2052789 through\r\nNataˇsa Pavlovi´","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","ddc":["530"],"oa":1},{"publication_status":"published","date_published":"2025-04-25T00:00:00Z","file_date_updated":"2025-05-12T08:23:10Z","article_type":"original","scopus_import":"1","day":"25","OA_type":"gold","fulldoi":"https://doi.org/10.5194/wcd-6-489-2025","PlanS_conform":"1","OA_place":"publisher","ec_funded":1,"type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"date_created":"2025-05-11T22:02:38Z","author":[{"full_name":"Gnanaraj, Abisha Mary","first_name":"Abisha Mary","last_name":"Gnanaraj"},{"id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160","last_name":"Bao","first_name":"Jiawei","full_name":"Bao, Jiawei"},{"last_name":"Schmidt","first_name":"Hauke","full_name":"Schmidt, Hauke"}],"month":"04","doi":"10.5194/wcd-6-489-2025","publication_identifier":{"eissn":["2698-4016"]},"citation":{"ieee":"A. M. Gnanaraj, J. Bao, and H. Schmidt, “The impact of the rotation rate on an aquaplanet’s radiant energy budget: Insights from experiments varying the Coriolis parameter,” <i>Weather and Climate Dynamics</i>, vol. 6, no. 2. Copernicus Publications, pp. 489–503, 2025.","mla":"Gnanaraj, Abisha Mary, et al. “The Impact of the Rotation Rate on an Aquaplanet’s Radiant Energy Budget: Insights from Experiments Varying the Coriolis Parameter.” <i>Weather and Climate Dynamics</i>, vol. 6, no. 2, Copernicus Publications, 2025, pp. 489–503, doi:<a href=\"https://doi.org/10.5194/wcd-6-489-2025\">10.5194/wcd-6-489-2025</a>.","apa":"Gnanaraj, A. M., Bao, J., &#38; Schmidt, H. (2025). The impact of the rotation rate on an aquaplanet’s radiant energy budget: Insights from experiments varying the Coriolis parameter. <i>Weather and Climate Dynamics</i>. Copernicus Publications. <a href=\"https://doi.org/10.5194/wcd-6-489-2025\">https://doi.org/10.5194/wcd-6-489-2025</a>","ista":"Gnanaraj AM, Bao J, Schmidt H. 2025. The impact of the rotation rate on an aquaplanet’s radiant energy budget: Insights from experiments varying the Coriolis parameter. Weather and Climate Dynamics. 6(2), 489–503.","ama":"Gnanaraj AM, Bao J, Schmidt H. The impact of the rotation rate on an aquaplanet’s radiant energy budget: Insights from experiments varying the Coriolis parameter. <i>Weather and Climate Dynamics</i>. 2025;6(2):489-503. doi:<a href=\"https://doi.org/10.5194/wcd-6-489-2025\">10.5194/wcd-6-489-2025</a>","short":"A.M. Gnanaraj, J. Bao, H. Schmidt, Weather and Climate Dynamics 6 (2025) 489–503.","chicago":"Gnanaraj, Abisha Mary, Jiawei Bao, and Hauke Schmidt. “The Impact of the Rotation Rate on an Aquaplanet’s Radiant Energy Budget: Insights from Experiments Varying the Coriolis Parameter.” <i>Weather and Climate Dynamics</i>. Copernicus Publications, 2025. <a href=\"https://doi.org/10.5194/wcd-6-489-2025\">https://doi.org/10.5194/wcd-6-489-2025</a>."},"publication":"Weather and Climate Dynamics","DOAJ_listed":"1","title":"The impact of the rotation rate on an aquaplanet's radiant energy budget: Insights from experiments varying the Coriolis parameter","quality_controlled":"1","issue":"2","file":[{"checksum":"2ea68f7e51ee39ccb6886719a83a78ca","file_id":"19680","content_type":"application/pdf","relation":"main_file","access_level":"open_access","date_updated":"2025-05-12T08:23:10Z","date_created":"2025-05-12T08:23:10Z","creator":"dernst","file_name":"2025_WeatherClimateDynam_Gnanaraj.pdf","success":1,"file_size":6500575}],"abstract":[{"lang":"eng","text":"We investigate the effect of changes in the Coriolis force caused by changes in the rotation rate on the top-of-atmosphere (TOA) radiant energy budget of an aquaplanet general circulation model with prescribed sea surface temperatures. We analyse the effective radiative forcing caused by changes from Earth-like rotation to values between 1/32 and 8 times the Earth's rotation rate. The forcing differs by about 60 W m−2 between the fastest and slowest rotation cases, with a monotonically increasing positive forcing for faster-than-Earth-like rotations and a non-monotonically increasing negative forcing for slower rotations. The largest contributions to the forcing are due to changes in, in this order, the shortwave cloud radiative effect (SWCRE) and the clear-sky outgoing longwave radiation (OLR). From the fastest to the slowest rotation, the Hadley cell expands and the troposphere becomes drier, increasing the OLR. This contributes to negative forcing at slower-than-Earth-like rotations and to positive forcing at faster-than-Earth-like rotations. The SWCRE is influenced by changes in the low-level cloudiness within the Hadley cell and the baroclinic regime. With the expansion of the Hadley cell, the area of enhanced tropospheric stability increases, resulting in more low-level clouds, a higher SWCRE, and increased negative forcing. The non-monotonicity results from an intermediate decrease in the SWCRE caused by the disappearance of baroclinic eddies as the Hadley cell reaches global extension. At rotations faster than Earth-like, the decrease in the SWCRE, mainly due to the weakening of baroclinic eddies and storm systems, leads to an increase in positive forcing. In summary, changes in the SWCRE, driven by different circulation responses at slower-than-Earth-like and faster-than-Earth-like rotations, strongly influence the TOA radiant energy budget. These effects, along with a substantial contribution from the clear-sky OLR, could impact the habitability of Earth-like rotating planets."}],"project":[{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"year":"2025","volume":6,"language":[{"iso":"eng"}],"oa_version":"Published Version","intvolume":"         6","department":[{"_id":"CaMu"}],"article_processing_charge":"Yes (via OA deal)","status":"public","date_updated":"2025-07-09T08:40:18Z","page":"489-503","_id":"19662","publisher":"Copernicus Publications","has_accepted_license":"1","oa":1,"ddc":["550"],"acknowledgement":"We thank Bjorn Stevens for suggesting the study and for substantial ideas along the way. We also thank Sebastian Rast for helping with the model compilation. This work used resources of the German Climate Computing Center (DKRZ) under project ID mh0066 for our experiments and analysis. Jiawei Bao acknowledges the European Union's Horizon 2020 for funding.Jiawei Bao has been supported by the European Union's Horizon 2020 research and innovation programme under a Marie Skłodowska-Curie grant (grant agreement no. 101034413).\r\nThe article processing charges for this open-access publication were covered by the Max Planck Society.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"publication_status":"published","date_published":"2025-04-25T00:00:00Z","file_date_updated":"2025-05-12T07:46:10Z","article_type":"original","scopus_import":"1","day":"25","OA_type":"gold","fulldoi":"https://doi.org/10.1126/sciadv.adx4047","OA_place":"publisher","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"date_created":"2025-05-11T22:02:38Z","author":[{"full_name":"Schmitt, Madeleine T.","first_name":"Madeleine T.","last_name":"Schmitt"},{"full_name":"Kroll, Janina","last_name":"Kroll","first_name":"Janina"},{"full_name":"Ruiz-Fernandez, Mauricio J.A.","last_name":"Ruiz-Fernandez","first_name":"Mauricio J.A."},{"full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","last_name":"Hauschild","orcid":"0000-0001-9843-3522","first_name":"Robert"},{"last_name":"Ghosh","first_name":"Shaunak","full_name":"Ghosh, Shaunak"},{"first_name":"Petra","last_name":"Kameritsch","full_name":"Kameritsch, Petra"},{"full_name":"Merrin, Jack","last_name":"Merrin","id":"4515C308-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5145-4609","first_name":"Jack"},{"last_name":"Schmid","first_name":"Johanna","full_name":"Schmid, Johanna"},{"full_name":"Stefanowski, Kasia","last_name":"Stefanowski","first_name":"Kasia"},{"full_name":"Thomae, Andreas W.","last_name":"Thomae","first_name":"Andreas W."},{"last_name":"Cheng","first_name":"Jingyuan","full_name":"Cheng, Jingyuan"},{"full_name":"Öztan, Gamze Naz","last_name":"Öztan","first_name":"Gamze Naz"},{"first_name":"Peter","last_name":"Konopka","full_name":"Konopka, Peter"},{"full_name":"Ortega, Germán Camargo","first_name":"Germán Camargo","last_name":"Ortega"},{"full_name":"Penz, Thomas","first_name":"Thomas","last_name":"Penz"},{"full_name":"Bach, Luisa","last_name":"Bach","first_name":"Luisa"},{"first_name":"Dirk","last_name":"Baumjohann","full_name":"Baumjohann, Dirk"},{"full_name":"Bock, Christoph","last_name":"Bock","first_name":"Christoph"},{"first_name":"Tobias","last_name":"Straub","full_name":"Straub, Tobias"},{"full_name":"Meissner, Felix","last_name":"Meissner","first_name":"Felix"},{"id":"3EB04B78-F248-11E8-B48F-1D18A9856A87","last_name":"Kiermaier","first_name":"Eva","orcid":"0000-0001-6165-5738","full_name":"Kiermaier, Eva"},{"full_name":"Renkawitz, Jörg","orcid":"0000-0003-2856-3369","first_name":"Jörg","id":"3F0587C8-F248-11E8-B48F-1D18A9856A87","last_name":"Renkawitz"}],"month":"04","article_number":"eadx4047","doi":"10.1126/sciadv.adx4047","publication_identifier":{"eissn":["2375-2548"]},"citation":{"ieee":"M. T. Schmitt <i>et al.</i>, “Protecting centrosomes from fracturing enables efficient cell navigation,” <i>Science Advances</i>, vol. 11, no. 17. AAAS, 2025.","apa":"Schmitt, M. T., Kroll, J., Ruiz-Fernandez, M. J. A., Hauschild, R., Ghosh, S., Kameritsch, P., … Renkawitz, J. (2025). Protecting centrosomes from fracturing enables efficient cell navigation. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.adx4047\">https://doi.org/10.1126/sciadv.adx4047</a>","ama":"Schmitt MT, Kroll J, Ruiz-Fernandez MJA, et al. Protecting centrosomes from fracturing enables efficient cell navigation. <i>Science Advances</i>. 2025;11(17). doi:<a href=\"https://doi.org/10.1126/sciadv.adx4047\">10.1126/sciadv.adx4047</a>","ista":"Schmitt MT, Kroll J, Ruiz-Fernandez MJA, Hauschild R, Ghosh S, Kameritsch P, Merrin J, Schmid J, Stefanowski K, Thomae AW, Cheng J, Öztan GN, Konopka P, Ortega GC, Penz T, Bach L, Baumjohann D, Bock C, Straub T, Meissner F, Kiermaier E, Renkawitz J. 2025. Protecting centrosomes from fracturing enables efficient cell navigation. Science Advances. 11(17), eadx4047.","mla":"Schmitt, Madeleine T., et al. “Protecting Centrosomes from Fracturing Enables Efficient Cell Navigation.” <i>Science Advances</i>, vol. 11, no. 17, eadx4047, AAAS, 2025, doi:<a href=\"https://doi.org/10.1126/sciadv.adx4047\">10.1126/sciadv.adx4047</a>.","short":"M.T. Schmitt, J. Kroll, M.J.A. Ruiz-Fernandez, R. Hauschild, S. Ghosh, P. Kameritsch, J. Merrin, J. Schmid, K. Stefanowski, A.W. Thomae, J. Cheng, G.N. Öztan, P. Konopka, G.C. Ortega, T. Penz, L. Bach, D. Baumjohann, C. Bock, T. Straub, F. Meissner, E. Kiermaier, J. Renkawitz, Science Advances 11 (2025).","chicago":"Schmitt, Madeleine T., Janina Kroll, Mauricio J.A. Ruiz-Fernandez, Robert Hauschild, Shaunak Ghosh, Petra Kameritsch, Jack Merrin, et al. “Protecting Centrosomes from Fracturing Enables Efficient Cell Navigation.” <i>Science Advances</i>. AAAS, 2025. <a href=\"https://doi.org/10.1126/sciadv.adx4047\">https://doi.org/10.1126/sciadv.adx4047</a>."},"publication":"Science Advances","DOAJ_listed":"1","title":"Protecting centrosomes from fracturing enables efficient cell navigation","pmid":1,"quality_controlled":"1","issue":"17","file":[{"creator":"dernst","date_created":"2025-05-12T07:46:10Z","date_updated":"2025-05-12T07:46:10Z","file_size":2707050,"success":1,"file_name":"2025_ScienceAdvance_Schmitt.pdf","file_id":"19679","content_type":"application/pdf","checksum":"e8ba22922fa5b23ccfcce8865f57226c","access_level":"open_access","relation":"main_file"}],"abstract":[{"lang":"eng","text":"The centrosome is a microtubule orchestrator, nucleating and anchoring microtubules that grow radially and exert forces on cargos. At the same time, mechanical stresses from the microenvironment and cellular shape changes compress and bend microtubules. Yet, centrosomes are membraneless organelles, raising the question of how centrosomes withstand mechanical forces. Here, we discover that centrosomes can deform and even fracture. We reveal that centrosomes experience deformations during navigational pathfinding within motile cells. Coherence of the centrosome is maintained by Dyrk3 and cNAP1, preventing fracturing by forces. While cells can compensate for the depletion of centriolar-based centrosomes, the fracturing of centrosomes impedes cellular function by generating coexisting microtubule organizing centers that compete during path navigation and thereby cause cellular entanglement in the microenvironment. Our findings show that cells actively maintain the integrity of the centrosome to withstand mechanical forces. These results suggest that centrosome stability preservation is fundamental, given that almost all cells in multicellular organisms experience forces."}],"project":[{"grant_number":"CZI01","name":"Tools for automation and feedback microscopy","_id":"c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473"}],"isi":1,"year":"2025","volume":11,"external_id":{"pmid":["40279414"],"isi":["001476113400016"]},"language":[{"iso":"eng"}],"oa_version":"Published Version","intvolume":"        11","department":[{"_id":"Bio"},{"_id":"NanoFab"}],"article_processing_charge":"Yes","date_updated":"2025-09-30T12:26:21Z","status":"public","_id":"19663","has_accepted_license":"1","publisher":"AAAS","ddc":["570"],"oa":1,"acknowledgement":"We thank L. Pelkmans and D. Dormann for providing Dyrk3-EGFP plasmids; M. Heuzé for providing a RFP-Pericentrin plasmid; T. Balla for providing a PH-Akt-GFP plasmid; E. Snaar-Jagalska for providing a pLenti-V6.3 Ultra-Chili plasmid; T. Tang for providing CEP120 a plasmid; D. Trono for providing pMD2.G and psSPAX2 plasmids; M. Sixt for providing EB3-mCherry and EMTB-mCherry plasmids as well as 3T3 fibroblasts, Lifeact-GFP Hoxb8 cells, and LX293 cells; M. Duggan for RNA isolation from migrating DCs; M. Schuster from the Biomedical Sequencing Facility at CeMM; J. Schwarz for providing Jurkat T cells; M. Götz for initial transcriptome analysis; M. Götz and F. Merino for discussion and sharing reagents; F. Gärtner for discussions and support; M. Benjamin Braun for critical reading of the manuscript; and the Core Facility Bioimaging, the Core Facility Flow Cytometry, and the Animal Core Facility of the Biomedical Center (BMC) for excellent support.\r\nThis work was supported by Peter Hans Hofschneider Professorship of the Stiftung Experimentelle Biomedizin (J.R.); German Research Foundation grant “CRC914, project A12” (J.R); German Research Foundation grant “SPP2332, project 492014049” (J.R.); LMU Institutional Strategy LMU-Excellent within the framework of the German Excellence Initiative (J.R.); Medical & Clinician Scientist Program (MCSP) LMU Munich (J.K.); Deutsche Forschungsgemeinschaft (DFG; German Research Foundation) under Germany’s Excellence Strategy – EXC2151 – 390873048 (D.B.); Deutsche Forschungsgemeinschaft (DFG; German Research Foundation) Grossgeräteantrag 457838313 and under Germany’s Excellence Strategy – EXC 2151 – 390873048 (E.K.); Ministry of Innovation, Science and Research of North-Rhine-Westphalia (fellowship AZ: 421-8.03.03.02-137069) (E.K.); TRA Life and Health (University of Bonn) as part of the Excellence Strategy of the federal and state governments (E.K.); and CZI grant DAF2020-225401 and grant (DOI https://doi.org/10.37921/120055ratwvi) from the Chan Zuckerberg Initiative DAF (R.H.).","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"has_accepted_license":"1","publisher":"American Physical Society","ddc":["530"],"oa":1,"acknowledgement":"The authors are grateful to Zlatko Papić, Dolev Bluvstein, Nishad Maskara, Marcello Dalmonte, Thomas Iadecola, and Johannes Feldmeier for insightful discussions. A. K., M. L., and M. S. acknowledge support by the European Research Council under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899). J.-Y. D. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 101034413.","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","file":[{"access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"19677","checksum":"b7f581291e20f152d0efc64727314ca2","success":1,"file_name":"2025_PhysReviewLetters_Kerschbaumer.pdf","file_size":1028993,"creator":"dernst","date_updated":"2025-05-12T07:33:38Z","date_created":"2025-05-12T07:33:38Z"}],"abstract":[{"text":"Persistent revivals recently observed in Rydberg atom simulators have challenged our understanding of thermalization and attracted much interest to the concept of quantum many-body scars (QMBSs). QMBSs are non-thermal highly excited eigenstates that coexist with typical eigenstates in the spectrum of many-body Hamiltonians, and have since been reported in multiple theoretical models, including the so-called PXP model, approximately realized by Rydberg simulators. At the same time, questions of how common QMBSs are and in what models they are physically realized remain open. In this Letter, we demonstrate that QMBSs exist in a broader family of models that includes and generalizes PXP to longer-range constraints and states with different periodicity. We show that in each model, multiple QMBS families can be found. Each of them relies on a different approximate algebra, leading to oscillatory dynamics in all cases. However, in contrast to the PXP model, their observation requires launching dynamics from weakly entangled initial states rather than from a product state. QMBSs reported here may be experimentally probed using Rydberg atom simulator in the regime of longer-range Rydberg blockades.","lang":"eng"}],"isi":1,"project":[{"call_identifier":"H2020","grant_number":"850899","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E"},{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"year":"2025","volume":134,"external_id":{"pmid":["40344113"],"arxiv":["2410.18913"],"isi":["001480669300011"]},"language":[{"iso":"eng"}],"oa_version":"Published Version","intvolume":"       134","department":[{"_id":"MaSe"}],"article_processing_charge":"Yes (via OA deal)","related_material":{"link":[{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/a-sky-full-of-quantum-scars/"}],"record":[{"status":"public","id":"19623","relation":"research_data"}]},"date_updated":"2026-06-10T08:40:51Z","status":"public","_id":"19664","doi":"10.1103/PhysRevLett.134.160401","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"citation":{"ieee":"A. Kerschbaumer, M. Ljubotina, M. Serbyn, and J.-Y. M. Desaules, “Quantum many-body scars beyond the PXP model in Rydberg simulators,” <i>Physical Review Letters</i>, vol. 134, no. 16. American Physical Society, 2025.","mla":"Kerschbaumer, Aron, et al. “Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.” <i>Physical Review Letters</i>, vol. 134, no. 16, 160401, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.134.160401\">10.1103/PhysRevLett.134.160401</a>.","ista":"Kerschbaumer A, Ljubotina M, Serbyn M, Desaules J-YM. 2025. Quantum many-body scars beyond the PXP model in Rydberg simulators. Physical Review Letters. 134(16), 160401.","ama":"Kerschbaumer A, Ljubotina M, Serbyn M, Desaules J-YM. Quantum many-body scars beyond the PXP model in Rydberg simulators. <i>Physical Review Letters</i>. 2025;134(16). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.134.160401\">10.1103/PhysRevLett.134.160401</a>","apa":"Kerschbaumer, A., Ljubotina, M., Serbyn, M., &#38; Desaules, J.-Y. M. (2025). Quantum many-body scars beyond the PXP model in Rydberg simulators. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.134.160401\">https://doi.org/10.1103/PhysRevLett.134.160401</a>","short":"A. Kerschbaumer, M. Ljubotina, M. Serbyn, J.-Y.M. Desaules, Physical Review Letters 134 (2025).","chicago":"Kerschbaumer, Aron, Marko Ljubotina, Maksym Serbyn, and Jean-Yves Marc Desaules. “Quantum Many-Body Scars beyond the PXP Model in Rydberg Simulators.” <i>Physical Review Letters</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/PhysRevLett.134.160401\">https://doi.org/10.1103/PhysRevLett.134.160401</a>."},"arxiv":1,"publication":"Physical Review Letters","title":"Quantum many-body scars beyond the PXP model in Rydberg simulators","pmid":1,"quality_controlled":"1","issue":"16","file_date_updated":"2025-05-12T07:33:38Z","date_published":"2025-04-22T00:00:00Z","publication_status":"published","article_type":"original","scopus_import":"1","day":"22","OA_type":"hybrid","fulldoi":"https://doi.org/10.1103/PhysRevLett.134.160401","OA_place":"publisher","ec_funded":1,"type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"date_created":"2025-05-11T22:02:38Z","author":[{"full_name":"Kerschbaumer, Aron","orcid":"0009-0002-2370-8661","first_name":"Aron","id":"ade85a9c-3200-11ee-973b-91c1eb240410","last_name":"Kerschbaumer"},{"full_name":"Ljubotina, Marko","last_name":"Ljubotina","id":"F75EE9BE-5C90-11EA-905D-16643DDC885E","first_name":"Marko","orcid":"0000-0003-0038-7068"},{"last_name":"Serbyn","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","first_name":"Maksym","orcid":"0000-0002-2399-5827","full_name":"Serbyn, Maksym"},{"full_name":"Desaules, Jean-Yves Marc","id":"6c292945-a610-11ed-9eec-c3be1ad62a80","last_name":"Desaules","first_name":"Jean-Yves Marc","orcid":"0000-0002-3749-6375"}],"article_number":"160401","month":"04"},{"corr_author":"1","abstract":[{"lang":"eng","text":"As AI-based decision-makers increasingly influence human lives, it is a growing concern that their decisions may be unfair or biased with respect to people's protected attributes, such as gender and race. Most existing bias prevention measures provide probabilistic fairness guarantees in the long run, and it is possible that the decisions are biased on any decision sequence of fixed length. We introduce *fairness shielding*, where a symbolic decision-maker---the fairness shield---continuously monitors the sequence of decisions of another deployed black-box decision-maker, and makes interventions so that a given fairness criterion is met while the total intervention costs are minimized. We present four different algorithms for computing fairness shields, among which one guarantees fairness over fixed horizons, and three guarantee fairness periodically after fixed intervals. Given a distribution over future decisions and their intervention costs, our algorithms solve different instances of bounded-horizon optimal control problems with different levels of computational costs and optimality guarantees. Our empirical evaluation demonstrates the effectiveness of these shields in ensuring fairness while maintaining cost efficiency across various scenarios."}],"project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093","call_identifier":"H2020"}],"volume":39,"year":"2025","conference":{"start_date":"2025-02-25","end_date":"2025-03-04","location":"Philadelphia, PA, United States","name":"AAAI: Conference on Artificial Intelligence"},"external_id":{"arxiv":["2412.11994"]},"language":[{"iso":"eng"}],"oa_version":"Preprint","intvolume":"        39","department":[{"_id":"ToHe"}],"article_processing_charge":"No","date_updated":"2026-02-16T12:24:30Z","status":"public","page":"15659-15668","_id":"19665","publisher":"Association for the Advancement of Artificial Intelligence","oa":1,"acknowledgement":"This work is partly supported by the European Research Council under Grant No.: ERC-2020-AdG 101020093. It is also partially supported by the State Government of Styria, Austria – Department Zukunftsfonds Steiermark.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-04-11T00:00:00Z","publication_status":"published","scopus_import":"1","day":"11","OA_type":"green","fulldoi":"https://doi.org/10.1609/aaai.v39i15.33719","OA_place":"repository","ec_funded":1,"type":"conference","date_created":"2025-05-11T22:02:39Z","author":[{"full_name":"Cano Cordoba, Filip","orcid":"0000-0002-0783-904X","first_name":"Filip","last_name":"Cano Cordoba","id":"708cad98-e86a-11ef-8098-bdae2d7c6af1"},{"full_name":"Henzinger, Thomas A","first_name":"Thomas A","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger"},{"full_name":"Könighofer, Bettina","last_name":"Könighofer","first_name":"Bettina"},{"full_name":"Kueffner, Konstantin","first_name":"Konstantin","orcid":"0000-0001-8974-2542","last_name":"Kueffner","id":"8121a2d0-dc85-11ea-9058-af578f3b4515"},{"full_name":"Mallik, Kaushik","id":"0834ff3c-6d72-11ec-94e0-b5b0a4fb8598","last_name":"Mallik","first_name":"Kaushik","orcid":"0000-0001-9864-7475"}],"month":"04","doi":"10.1609/aaai.v39i15.33719","publication_identifier":{"issn":["2159-5399"],"eissn":["2374-3468"]},"citation":{"chicago":"Cano Cordoba, Filip, Thomas A Henzinger, Bettina Könighofer, Konstantin Kueffner, and Kaushik Mallik. “Fairness Shields: Safeguarding against Biased Decision Makers.” In <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, 39:15659–68. Association for the Advancement of Artificial Intelligence, 2025. <a href=\"https://doi.org/10.1609/aaai.v39i15.33719\">https://doi.org/10.1609/aaai.v39i15.33719</a>.","short":"F. Cano Cordoba, T.A. Henzinger, B. Könighofer, K. Kueffner, K. Mallik, in:, Proceedings of the 39th AAAI Conference on Artificial Intelligence, Association for the Advancement of Artificial Intelligence, 2025, pp. 15659–15668.","mla":"Cano Cordoba, Filip, et al. “Fairness Shields: Safeguarding against Biased Decision Makers.” <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, vol. 39, no. 15, Association for the Advancement of Artificial Intelligence, 2025, pp. 15659–68, doi:<a href=\"https://doi.org/10.1609/aaai.v39i15.33719\">10.1609/aaai.v39i15.33719</a>.","apa":"Cano Cordoba, F., Henzinger, T. A., Könighofer, B., Kueffner, K., &#38; Mallik, K. (2025). Fairness shields: Safeguarding against biased decision makers. In <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i> (Vol. 39, pp. 15659–15668). Philadelphia, PA, United States: Association for the Advancement of Artificial Intelligence. <a href=\"https://doi.org/10.1609/aaai.v39i15.33719\">https://doi.org/10.1609/aaai.v39i15.33719</a>","ama":"Cano Cordoba F, Henzinger TA, Könighofer B, Kueffner K, Mallik K. Fairness shields: Safeguarding against biased decision makers. In: <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>. Vol 39. Association for the Advancement of Artificial Intelligence; 2025:15659-15668. doi:<a href=\"https://doi.org/10.1609/aaai.v39i15.33719\">10.1609/aaai.v39i15.33719</a>","ista":"Cano Cordoba F, Henzinger TA, Könighofer B, Kueffner K, Mallik K. 2025. Fairness shields: Safeguarding against biased decision makers. Proceedings of the 39th AAAI Conference on Artificial Intelligence. AAAI: Conference on Artificial Intelligence vol. 39, 15659–15668.","ieee":"F. Cano Cordoba, T. A. Henzinger, B. Könighofer, K. Kueffner, and K. Mallik, “Fairness shields: Safeguarding against biased decision makers,” in <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, Philadelphia, PA, United States, 2025, vol. 39, no. 15, pp. 15659–15668."},"arxiv":1,"publication":"Proceedings of the 39th AAAI Conference on Artificial Intelligence","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2412.11994","open_access":"1"}],"title":"Fairness shields: Safeguarding against biased decision makers","quality_controlled":"1","issue":"15"},{"project":[{"name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020"}],"abstract":[{"lang":"eng","text":"Markov decision processes (MDP) are a well-established model for sequential decision-making in the presence of probabilities. In *robust* MDP (RMDP), every action is associated with an *uncertainty set* of probability distributions, modelling that transition probabilities are not known precisely. Based on the known theoretical connection to stochastic games, we provide a framework for solving RMDPs that is generic, reliable, and efficient. It is *generic* both with respect to the model, allowing for a wide range of uncertainty sets, including but not limited to intervals, L1- or L2-balls, and polytopes; and with respect to the objective, including long-run average reward, undiscounted total reward, and stochastic shortest path. It is *reliable*, as our approach not only converges in the limit, but provides precision guarantees at any time during the computation. It is *efficient* because -- in contrast to state-of-the-art approaches -- it avoids explicitly constructing the underlying stochastic game. Consequently, our prototype implementation outperforms existing tools by several orders of magnitude and can solve RMDPs with a million states in under a minute."}],"language":[{"iso":"eng"}],"oa_version":"Preprint","year":"2025","volume":39,"external_id":{"arxiv":["2412.10185"]},"conference":{"location":"Philadelphia, PA, United States","name":"AAAI: Conference on Artificial Intelligence","end_date":"2025-03-04","start_date":"2025-02-25"},"department":[{"_id":"KrCh"}],"intvolume":"        39","page":"26631-26641","_id":"19666","article_processing_charge":"No","status":"public","date_updated":"2026-02-16T12:25:05Z","related_material":{"link":[{"relation":"software","url":"https://doi.org/10.5281/zenodo.14385449"}]},"publisher":"Association for the Advancement of Artificial Intelligence","acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 101034413,\r\nthe ERC CoG 863818 (ForM-SMArt), and the DFG through the Cluster of Excellence EXC 2050/1 (CeTI, project ID 390696704, as part of Germany’s Excellence Strategy) and the TRR 248 (see https://perspicuous-computing.science, project ID 389792660).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"OA_type":"green","day":"11","fulldoi":"https://doi.org/10.1609/aaai.v39i25.34865","date_published":"2025-04-11T00:00:00Z","publication_status":"published","scopus_import":"1","OA_place":"repository","type":"conference","ec_funded":1,"author":[{"full_name":"Meggendorfer, Tobias","orcid":"0000-0002-1712-2165","first_name":"Tobias","last_name":"Meggendorfer","id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1"},{"full_name":"Weininger, Maximilian","orcid":"0000-0002-0163-2152","first_name":"Maximilian","last_name":"Weininger","id":"02ab0197-cc70-11ed-ab61-918e71f56881"},{"last_name":"Wienhöft","first_name":"Patrick","full_name":"Wienhöft, Patrick"}],"month":"04","date_created":"2025-05-11T22:02:39Z","publication_identifier":{"eissn":["2374-3468"],"issn":["2159-5399"]},"citation":{"ieee":"T. Meggendorfer, M. Weininger, and P. Wienhöft, “Solving robust Markov decision processes: Generic, reliable, efficient,” in <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, Philadelphia, PA, United States, 2025, vol. 39, no. 25, pp. 26631–26641.","ama":"Meggendorfer T, Weininger M, Wienhöft P. Solving robust Markov decision processes: Generic, reliable, efficient. In: <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>. Vol 39. Association for the Advancement of Artificial Intelligence; 2025:26631-26641. doi:<a href=\"https://doi.org/10.1609/aaai.v39i25.34865\">10.1609/aaai.v39i25.34865</a>","ista":"Meggendorfer T, Weininger M, Wienhöft P. 2025. Solving robust Markov decision processes: Generic, reliable, efficient. Proceedings of the 39th AAAI Conference on Artificial Intelligence. AAAI: Conference on Artificial Intelligence vol. 39, 26631–26641.","apa":"Meggendorfer, T., Weininger, M., &#38; Wienhöft, P. (2025). Solving robust Markov decision processes: Generic, reliable, efficient. In <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i> (Vol. 39, pp. 26631–26641). Philadelphia, PA, United States: Association for the Advancement of Artificial Intelligence. <a href=\"https://doi.org/10.1609/aaai.v39i25.34865\">https://doi.org/10.1609/aaai.v39i25.34865</a>","mla":"Meggendorfer, Tobias, et al. “Solving Robust Markov Decision Processes: Generic, Reliable, Efficient.” <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, vol. 39, no. 25, Association for the Advancement of Artificial Intelligence, 2025, pp. 26631–41, doi:<a href=\"https://doi.org/10.1609/aaai.v39i25.34865\">10.1609/aaai.v39i25.34865</a>.","short":"T. Meggendorfer, M. Weininger, P. Wienhöft, in:, Proceedings of the 39th AAAI Conference on Artificial Intelligence, Association for the Advancement of Artificial Intelligence, 2025, pp. 26631–26641.","chicago":"Meggendorfer, Tobias, Maximilian Weininger, and Patrick Wienhöft. “Solving Robust Markov Decision Processes: Generic, Reliable, Efficient.” In <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, 39:26631–41. Association for the Advancement of Artificial Intelligence, 2025. <a href=\"https://doi.org/10.1609/aaai.v39i25.34865\">https://doi.org/10.1609/aaai.v39i25.34865</a>."},"arxiv":1,"doi":"10.1609/aaai.v39i25.34865","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2412.10185"}],"title":"Solving robust Markov decision processes: Generic, reliable, efficient","publication":"Proceedings of the 39th AAAI Conference on Artificial Intelligence","issue":"25","quality_controlled":"1"},{"date_published":"2025-04-11T00:00:00Z","publication_status":"published","scopus_import":"1","day":"11","OA_type":"green","fulldoi":"https://doi.org/10.1609/aaai.v39i25.34840","OA_place":"repository","ec_funded":1,"type":"conference","date_created":"2025-05-11T22:02:40Z","author":[{"first_name":"Zhengqi","id":"20aa2ae8-f2f1-11ed-bbfa-8205053f1342","last_name":"Yu","full_name":"Yu, Zhengqi"},{"last_name":"Zikelic","id":"294AA7A6-F248-11E8-B48F-1D18A9856A87","first_name":"Dorde","orcid":"0000-0002-4681-1699","full_name":"Zikelic, Dorde"},{"first_name":"Thomas A","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger","full_name":"Henzinger, Thomas A"}],"month":"04","doi":"10.1609/aaai.v39i25.34840","publication_identifier":{"issn":["2159-5399"],"eissn":["2374-3468"]},"citation":{"short":"E. Yu, D. Zikelic, T.A. Henzinger, in:, Proceedings of the 39th AAAI Conference on Artificial Intelligence, Association for the Advancement of Artificial Intelligence, 2025, pp. 26409–26417.","chicago":"Yu, Emily, Dorde Zikelic, and Thomas A Henzinger. “Neural Control and Certificate Repair via Runtime Monitoring.” In <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, 39:26409–17. Association for the Advancement of Artificial Intelligence, 2025. <a href=\"https://doi.org/10.1609/aaai.v39i25.34840\">https://doi.org/10.1609/aaai.v39i25.34840</a>.","ieee":"E. Yu, D. Zikelic, and T. A. Henzinger, “Neural control and certificate repair via runtime monitoring,” in <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, Philadelphia, PA, United States, 2025, vol. 39, no. 25, pp. 26409–26417.","apa":"Yu, E., Zikelic, D., &#38; Henzinger, T. A. (2025). Neural control and certificate repair via runtime monitoring. In <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i> (Vol. 39, pp. 26409–26417). Philadelphia, PA, United States: Association for the Advancement of Artificial Intelligence. <a href=\"https://doi.org/10.1609/aaai.v39i25.34840\">https://doi.org/10.1609/aaai.v39i25.34840</a>","ama":"Yu E, Zikelic D, Henzinger TA. Neural control and certificate repair via runtime monitoring. In: <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>. Vol 39. Association for the Advancement of Artificial Intelligence; 2025:26409-26417. doi:<a href=\"https://doi.org/10.1609/aaai.v39i25.34840\">10.1609/aaai.v39i25.34840</a>","ista":"Yu E, Zikelic D, Henzinger TA. 2025. Neural control and certificate repair via runtime monitoring. Proceedings of the 39th AAAI Conference on Artificial Intelligence. AAAI: Conference on Artificial Intelligence vol. 39, 26409–26417.","mla":"Yu, Emily, et al. “Neural Control and Certificate Repair via Runtime Monitoring.” <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, vol. 39, no. 25, Association for the Advancement of Artificial Intelligence, 2025, pp. 26409–17, doi:<a href=\"https://doi.org/10.1609/aaai.v39i25.34840\">10.1609/aaai.v39i25.34840</a>."},"arxiv":1,"publication":"Proceedings of the 39th AAAI Conference on Artificial Intelligence","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2412.12996"}],"title":"Neural control and certificate repair via runtime monitoring","quality_controlled":"1","issue":"25","corr_author":"1","abstract":[{"text":"Learning-based methods provide a promising approach to solving highly non-linear control tasks that are often challenging for classical control methods. To ensure the satisfaction of a safety property, learning-based methods jointly learn a control policy together with a certificate function for the property. Popular examples include barrier functions for safety and Lyapunov functions for asymptotic stability. While there has been significant progress on learning-based control with certificate functions in the white-box setting, where the correctness of the certificate function can be formally verified, there has been little work on ensuring their reliability in the black-box setting where the system dynamics are unknown. In this work, we consider the problems of certifying and repairing neural network control policies and certificate functions in the black-box setting. We propose a novel framework that utilizes runtime monitoring to detect system behaviors that violate the property of interest under some initially trained neural network policy and certificate. These violating behaviors are used to extract new training data, that is used to re-train the neural network policy and the certificate function and to ultimately repair them. We demonstrate the effectiveness of our approach empirically by using it to repair and to boost the safety rate of neural network policies learned by a state-of-the-art method for learning-based control on two autonomous system control tasks.","lang":"eng"}],"project":[{"name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","call_identifier":"H2020"}],"year":"2025","volume":39,"conference":{"name":"AAAI: Conference on Artificial Intelligence","location":"Philadelphia, PA, United States","start_date":"2025-02-25","end_date":"2025-03-04"},"external_id":{"arxiv":["2412.12996"]},"language":[{"iso":"eng"}],"oa_version":"Preprint","intvolume":"        39","department":[{"_id":"ToHe"}],"article_processing_charge":"No","date_updated":"2025-05-12T09:49:25Z","status":"public","page":"26409-26417","_id":"19668","publisher":"Association for the Advancement of Artificial Intelligence","oa":1,"acknowledgement":"This work was supported in part by the ERC project ERC2020-AdG 101020093","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"issue":"4","quality_controlled":"1","publication_identifier":{"issn":["1070-6631"],"eissn":["1089-7666"]},"citation":{"ieee":"G. Bartolucci <i>et al.</i>, “Phase behavior of Cacio e Pepe sauce,” <i>Physics of Fluids</i>, vol. 37, no. 4. AIP Publishing, 2025.","ama":"Bartolucci G, Busiello DM, Ciarchi M, et al. Phase behavior of Cacio e Pepe sauce. <i>Physics of Fluids</i>. 2025;37(4). doi:<a href=\"https://doi.org/10.1063/5.0255841\">10.1063/5.0255841</a>","apa":"Bartolucci, G., Busiello, D. M., Ciarchi, M., Corticelli, A., Di Terlizzi, I., Olmeda, F., … Schimmenti, V. M. (2025). Phase behavior of Cacio e Pepe sauce. <i>Physics of Fluids</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0255841\">https://doi.org/10.1063/5.0255841</a>","ista":"Bartolucci G, Busiello DM, Ciarchi M, Corticelli A, Di Terlizzi I, Olmeda F, Revignas D, Schimmenti VM. 2025. Phase behavior of Cacio e Pepe sauce. Physics of Fluids. 37(4), 044122.","mla":"Bartolucci, G., et al. “Phase Behavior of Cacio e Pepe Sauce.” <i>Physics of Fluids</i>, vol. 37, no. 4, 044122, AIP Publishing, 2025, doi:<a href=\"https://doi.org/10.1063/5.0255841\">10.1063/5.0255841</a>.","short":"G. Bartolucci, D.M. Busiello, M. Ciarchi, A. Corticelli, I. Di Terlizzi, F. Olmeda, D. Revignas, V.M. Schimmenti, Physics of Fluids 37 (2025).","chicago":"Bartolucci, G., D. M. Busiello, M. Ciarchi, A. Corticelli, I. Di Terlizzi, Fabrizio Olmeda, D. Revignas, and V. M. Schimmenti. “Phase Behavior of Cacio e Pepe Sauce.” <i>Physics of Fluids</i>. AIP Publishing, 2025. <a href=\"https://doi.org/10.1063/5.0255841\">https://doi.org/10.1063/5.0255841</a>."},"arxiv":1,"doi":"10.1063/5.0255841","title":"Phase behavior of Cacio e Pepe sauce","publication":"Physics of Fluids","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","author":[{"full_name":"Bartolucci, G.","last_name":"Bartolucci","first_name":"G."},{"full_name":"Busiello, D. M.","last_name":"Busiello","first_name":"D. M."},{"first_name":"M.","last_name":"Ciarchi","full_name":"Ciarchi, M."},{"full_name":"Corticelli, A.","last_name":"Corticelli","first_name":"A."},{"full_name":"Di Terlizzi, I.","last_name":"Di Terlizzi","first_name":"I."},{"full_name":"Olmeda, Fabrizio","first_name":"Fabrizio","id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","last_name":"Olmeda"},{"full_name":"Revignas, D.","last_name":"Revignas","first_name":"D."},{"first_name":"V. M.","last_name":"Schimmenti","full_name":"Schimmenti, V. M."}],"article_number":"044122","month":"04","date_created":"2025-05-11T22:02:40Z","day":"01","OA_type":"hybrid","fulldoi":"https://doi.org/10.1063/5.0255841","article_type":"original","file_date_updated":"2025-05-12T09:31:22Z","publication_status":"published","date_published":"2025-04-01T00:00:00Z","scopus_import":"1","OA_place":"publisher","acknowledgement":"he authors thank Frank Jülicher, for supporting the initiative and stimulating discussions. We thank Tetsuya Spippayashi for enlightening clarifications on the historical origins of Cacio e pepe and Giuseppe Ricchitelli for helping with the construction of the experimental apparatus. We further thank Martina Gaiba, Alessandro Gaiba, John D. Treado, Virginia Lepore, Eleonora Nanu, Julia Kirsch, Lara Koehler, Burak Budanur, Irina Pi-Jaumà, Elizabeth Brückner, M.J. Franco Oñate, Giorgio Nicoletti, and Marco Salvalaglio for their support and for eating up the sample leftovers. Finally, we thank Simone Frau for taking the photograph in Fig. 1(a).","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","ddc":["530"],"oa":1,"has_accepted_license":"1","publisher":"AIP Publishing","department":[{"_id":"EdHa"}],"intvolume":"        37","_id":"19670","article_processing_charge":"Yes (in subscription journal)","related_material":{"link":[{"relation":"press_release","description":"News on ISTA","url":"https://ista.ac.at/en/news/2025-ig-nobel-prize-for-perfect-pasta-sauce/"}]},"status":"public","date_updated":"2026-04-28T13:24:53Z","isi":1,"file":[{"access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"19681","checksum":"242d05898aa0a2348b9c108747adb5ce","file_name":"2025_PhysicsFluids_Bartolucci.pdf","file_size":4926853,"success":1,"creator":"dernst","date_created":"2025-05-12T09:31:22Z","date_updated":"2025-05-12T09:31:22Z"}],"abstract":[{"lang":"eng","text":"“Pasta alla Cacio e pepe” is a traditional Italian dish made with pasta, pecorino cheese, and pepper. Despite its simple ingredient list, achieving the perfect texture and creaminess of the sauce can be challenging. In this study, we systematically explore the phase behavior of Cacio e pepe sauce, focusing on its stability at increasing temperatures for various proportions of cheese, water, and starch. We identify starch concentration as the key factor influencing sauce stability, with direct implications for practical cooking. Specifically, we delineate a regime where starch concentrations below 1% (relative to cheese mass) lead to the formation of system-wide clumps, a condition determining what we term the “Mozzarella Phase” and corresponding to an unpleasant and separated sauce. Additionally, we examine the impact of cheese concentration relative to water at a fixed starch level, observing a lower critical solution temperature that we theoretically rationalized by means of a minimal effective free-energy model. We further analyze the effect of a less traditional stabilizer, trisodium citrate, and observe a sharp transition from the Mozzarella Phase to a completely smooth and stable sauce, in contrast to starch-stabilized mixtures, where the transition is more gradual. Finally, we present a scientifically optimized recipe based on our findings, enabling a consistently flawless execution of this classic dish."}],"language":[{"iso":"eng"}],"oa_version":"Published Version","volume":37,"year":"2025","external_id":{"isi":["001482986200001"],"arxiv":["2501.00536"]}},{"date_published":"2025-04-01T00:00:00Z","article_type":"original","publication_status":"published","scopus_import":"1","day":"01","OA_type":"closed access","fulldoi":"https://doi.org/10.1111/aec.70058","type":"journal_article","date_created":"2025-05-11T22:02:41Z","author":[{"full_name":"Arpigiani, Daniela","last_name":"Arpigiani","first_name":"Daniela"},{"first_name":"Valeria","last_name":"Aschero","full_name":"Aschero, Valeria"},{"full_name":"Soler Schaller, Rosina Matilde","first_name":"Rosina Matilde","last_name":"Soler Schaller","id":"9e668447-8c32-11ed-b0c7-8dc2d7b80803"},{"first_name":"Mariano M.","last_name":"Amoroso","full_name":"Amoroso, Mariano M."}],"month":"04","article_number":"e70058","doi":"10.1111/aec.70058","citation":{"short":"D. Arpigiani, V. Aschero, R.M. Soler Schaller, M.M. Amoroso, Austral Ecology 50 (2025).","chicago":"Arpigiani, Daniela, Valeria Aschero, Rosina Matilde Soler Schaller, and Mariano M. Amoroso. “A Life-Cycle Approach to Understand Consequences of Silvopastoral Use on Two Native Tree Species of Northern Patagonia.” <i>Austral Ecology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/aec.70058\">https://doi.org/10.1111/aec.70058</a>.","ieee":"D. Arpigiani, V. Aschero, R. M. Soler Schaller, and M. M. Amoroso, “A life-cycle approach to understand consequences of silvopastoral use on two native tree species of Northern Patagonia,” <i>Austral Ecology</i>, vol. 50, no. 4. Wiley, 2025.","ama":"Arpigiani D, Aschero V, Soler Schaller RM, Amoroso MM. A life-cycle approach to understand consequences of silvopastoral use on two native tree species of Northern Patagonia. <i>Austral Ecology</i>. 2025;50(4). doi:<a href=\"https://doi.org/10.1111/aec.70058\">10.1111/aec.70058</a>","apa":"Arpigiani, D., Aschero, V., Soler Schaller, R. M., &#38; Amoroso, M. M. (2025). A life-cycle approach to understand consequences of silvopastoral use on two native tree species of Northern Patagonia. <i>Austral Ecology</i>. Wiley. <a href=\"https://doi.org/10.1111/aec.70058\">https://doi.org/10.1111/aec.70058</a>","ista":"Arpigiani D, Aschero V, Soler Schaller RM, Amoroso MM. 2025. A life-cycle approach to understand consequences of silvopastoral use on two native tree species of Northern Patagonia. Austral Ecology. 50(4), e70058.","mla":"Arpigiani, Daniela, et al. “A Life-Cycle Approach to Understand Consequences of Silvopastoral Use on Two Native Tree Species of Northern Patagonia.” <i>Austral Ecology</i>, vol. 50, no. 4, e70058, Wiley, 2025, doi:<a href=\"https://doi.org/10.1111/aec.70058\">10.1111/aec.70058</a>."},"publication_identifier":{"issn":["1442-9985"],"eissn":["1442-9993"]},"publication":"Austral Ecology","title":"A life-cycle approach to understand consequences of silvopastoral use on two native tree species of Northern Patagonia","quality_controlled":"1","issue":"4","abstract":[{"text":"Silvopastoral use in native forests could impact population dynamics of key tree species, with contrasting effects at different life cycle stages. Prior studies in South American temperate forests have mainly focused on initial stages, lacking a comprehensive understanding of the entire life cycle within productive systems. We assessed the population dynamics of two key species of mixed forests in northern Patagonia (Austrocedrus chilensis and Nothofagus dombeyi) under two silvopastoral use intensities (high vs. low), using demographic techniques and population projection models. Over 3 years, we quantified vital rates (survival, fertility, growth, reversion and stasis) and used matrix models to calculate deterministic population growth rates (λ). High-intensity silvopastoral use had predominantly negative effects on the elements of the projection matrices of A. chilensis, whereas N. dombeyi exhibited mostly positive or no changes. As a result, projections indicated slight population decreases for A. chilensis (mostly λ < 1) at high silvopastoral use levels compared to low levels, while N. dombeyi showed similar projections (λ ≅ 1) between use levels. Decreased λ for A. chilensis resulted mainly from lower adult tree survival, while early life stages had limited influence on λ for these long-lived species. In summary, silvopastoral use affects population dynamics of key tree species of these mixed forests of northern Patagonia, with implications for sustainable management. Our findings highlight the importance of considering the entire life cycle and suggest targeted practices to enhance A. chilensis populations.","lang":"eng"}],"isi":1,"volume":50,"year":"2025","external_id":{"isi":["001476761500001"]},"language":[{"iso":"eng"}],"oa_version":"None","intvolume":"        50","department":[{"_id":"NiBa"}],"article_processing_charge":"No","date_updated":"2025-09-30T12:31:04Z","status":"public","_id":"19671","publisher":"Wiley","acknowledgement":"We would like to express our sincere gratitude to the owners of the estates, Lisandro and Oscar Lanfré, Roberto Criado and Yayo Tillería, for allowing us to conduct our research on their properties and for generously sharing their time and knowledge throughout these years. We are also deeply thankful to our field assistants, Matías Scotti, Clara Pissolito, Noel Szudruk, Mariano Varela, Ian Mott, Brisa Guenuleo, Nicolás Bistolfi, Facundo Gómez and Belén Vallerga, who tirelessly collaborated in the arduous tasks of monitoring and data collection, even in challenging weather conditions. We are grateful to CONICET for providing the doctoral scholarship to D. Arpigiani. This study received partial financial support from the Agencia MINCyT (PICT 2015-1692) and the Universidad Nacional de Río Negro (PI 40-B-478), Argentina.","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"OA_place":"publisher","fulldoi":"https://doi.org/10.1029/2024MS004613","OA_type":"gold","day":"01","scopus_import":"1","date_published":"2025-04-01T00:00:00Z","file_date_updated":"2025-05-12T12:17:08Z","article_type":"original","publication_status":"published","article_number":"e2024MS004613","month":"04","author":[{"full_name":"Polesello, Andrea","first_name":"Andrea","id":"74c777f4-32da-11ee-b498-874db0835561","last_name":"Polesello"},{"full_name":"Charinti, Giousef Alexandros","first_name":"Giousef Alexandros","last_name":"Charinti","id":"7f7cc04c-074c-11ed-af92-eb16afd85c75"},{"last_name":"Meroni","first_name":"Agostino Niyonkuru","full_name":"Meroni, Agostino Niyonkuru"},{"full_name":"Muller, Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","last_name":"Muller","first_name":"Caroline J","orcid":"0000-0001-5836-5350"},{"full_name":"Pasquero, Claudia","last_name":"Pasquero","first_name":"Claudia"}],"date_created":"2025-05-11T22:02:41Z","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"ec_funded":1,"title":"Intensity oscillations of tropical cyclones: Surface versus mid and upper tropospheric processes","DOAJ_listed":"1","publication":"Journal of Advances in Modeling Earth Systems","publication_identifier":{"eissn":["1942-2466"]},"citation":{"short":"A. Polesello, G.A. Charinti, A.N. Meroni, C.J. Muller, C. Pasquero, Journal of Advances in Modeling Earth Systems 17 (2025).","chicago":"Polesello, Andrea, Giousef Alexandros Charinti, Agostino Niyonkuru Meroni, Caroline J Muller, and Claudia Pasquero. “Intensity Oscillations of Tropical Cyclones: Surface versus Mid and Upper Tropospheric Processes.” <i>Journal of Advances in Modeling Earth Systems</i>. Wiley, 2025. <a href=\"https://doi.org/10.1029/2024MS004613\">https://doi.org/10.1029/2024MS004613</a>.","ieee":"A. Polesello, G. A. Charinti, A. N. Meroni, C. J. Muller, and C. Pasquero, “Intensity oscillations of tropical cyclones: Surface versus mid and upper tropospheric processes,” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 17, no. 4. Wiley, 2025.","ista":"Polesello A, Charinti GA, Meroni AN, Muller CJ, Pasquero C. 2025. Intensity oscillations of tropical cyclones: Surface versus mid and upper tropospheric processes. Journal of Advances in Modeling Earth Systems. 17(4), e2024MS004613.","apa":"Polesello, A., Charinti, G. A., Meroni, A. N., Muller, C. J., &#38; Pasquero, C. (2025). Intensity oscillations of tropical cyclones: Surface versus mid and upper tropospheric processes. <i>Journal of Advances in Modeling Earth Systems</i>. Wiley. <a href=\"https://doi.org/10.1029/2024MS004613\">https://doi.org/10.1029/2024MS004613</a>","ama":"Polesello A, Charinti GA, Meroni AN, Muller CJ, Pasquero C. Intensity oscillations of tropical cyclones: Surface versus mid and upper tropospheric processes. <i>Journal of Advances in Modeling Earth Systems</i>. 2025;17(4). doi:<a href=\"https://doi.org/10.1029/2024MS004613\">10.1029/2024MS004613</a>","mla":"Polesello, Andrea, et al. “Intensity Oscillations of Tropical Cyclones: Surface versus Mid and Upper Tropospheric Processes.” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 17, no. 4, e2024MS004613, Wiley, 2025, doi:<a href=\"https://doi.org/10.1029/2024MS004613\">10.1029/2024MS004613</a>."},"doi":"10.1029/2024MS004613","issue":"4","quality_controlled":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"external_id":{"isi":["001472439600001"]},"year":"2025","volume":17,"isi":1,"project":[{"call_identifier":"H2020","grant_number":"805041","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","_id":"629205d8-2b32-11ec-9570-e1356ff73576"}],"abstract":[{"text":"Some of the classical models of tropical cyclone intensification predict tropical cyclones to intensify up to a steady intensity, which depends on surface fluxes only, without any relevant role played by convective motions in the troposphere, typically assumed to have a moist adiabatic lapse rate. Simulations performed using the non-hydrostatic, high-resolution model System for Atmosphere Modeling in idealized settings (rotating radiative-convective equilibrium on a doubly periodic domain) show early intensification consistent with these theoretical expectations, but different intensity evolution, with the cyclone undergoing an oscillation in wind speed. This oscillation can be linked to feedbacks between the cyclone intensity and air buoyancy: convective heating, radiative heating, and mixing with warm low stratospheric air warm the mid and upper troposphere of the cyclone stabilizing the air column and thus reducing its intensity. After the intensity decay phase, mid and upper tropospheric cooling, mostly through cold advection from the surroundings, cooled by radiation, rebuilds Convective Available Potential Energy, that peaks just before a new intensification phase. These idealized simulations thus highlight the potentially important interactions between a tropical cyclone, its environment and radiation.","lang":"eng"}],"corr_author":"1","file":[{"file_size":942325,"file_name":"2025_JAMES_Polesello.pdf","success":1,"date_updated":"2025-05-12T12:17:08Z","date_created":"2025-05-12T12:17:08Z","creator":"dernst","relation":"main_file","access_level":"open_access","checksum":"2f7c74aceaeea4be1fff4de300791319","content_type":"application/pdf","file_id":"19683"}],"_id":"19672","date_updated":"2025-09-30T12:30:29Z","status":"public","article_processing_charge":"Yes","department":[{"_id":"CaMu"}],"intvolume":"        17","has_accepted_license":"1","publisher":"Wiley","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"The authors acknowledge two anonymous reviewers and the editor who provided insightful remarks and comments that helped to significantly improve the manuscript. AP and CJM gratefully acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). Part of this work is an outcome of the project MIUR—Dipartimenti di Eccellenza 2023–2027. ANM is supported by HPC-TRES Grant 2023-04.","ddc":["550"],"oa":1},{"has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","title":"Dataset for \"Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State\"","license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","citation":{"ieee":"B. Tatman, “Dataset for ‘Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State.’” Institute of Science and Technology Austria, 2025.","ista":"Tatman B. 2025. Dataset for ‘Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-19696\">10.15479/AT-ISTA-19696</a>.","ama":"Tatman B. Dataset for “Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State.” 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19696\">10.15479/AT-ISTA-19696</a>","apa":"Tatman, B. (2025). Dataset for “Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-19696\">https://doi.org/10.15479/AT-ISTA-19696</a>","mla":"Tatman, Benjamin. <i>Dataset for “Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State.”</i> Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19696\">10.15479/AT-ISTA-19696</a>.","short":"B. Tatman, (2025).","chicago":"Tatman, Benjamin. “Dataset for ‘Bumps on the Road: The Way to Clean Relaxation Dispersion in the Solid State.’” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-19696\">https://doi.org/10.15479/AT-ISTA-19696</a>."},"doi":"10.15479/AT-ISTA-19696","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","oa":1,"oa_version":"Published Version","year":"2025","fulldoi":"https://doi.org/10.15479/AT-ISTA-19696","day":"31","corr_author":"1","file_date_updated":"2025-07-31T08:14:40Z","date_published":"2025-07-31T00:00:00Z","file":[{"checksum":"4c2d29404e070bda7d5619f728ec555c","file_id":"20094","content_type":"application/zip","relation":"main_file","access_level":"open_access","date_updated":"2025-07-31T08:14:40Z","date_created":"2025-07-31T08:14:40Z","creator":"btatman","file_name":"dataset.zip","file_size":557878455,"success":1},{"access_level":"open_access","relation":"main_file","content_type":"text/plain","file_id":"20095","checksum":"6cbccd602be0ecb6ddb1f81fdfcadf92","file_size":3514,"file_name":"readme.txt","success":1,"creator":"btatman","date_created":"2025-07-31T08:14:21Z","date_updated":"2025-07-31T08:14:21Z"}],"_id":"19696","month":"07","contributor":[{"orcid":"0000-0002-9350-7606","first_name":"Paul","contributor_type":"project_leader","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","last_name":"Schanda"},{"contributor_type":"researcher","first_name":"Vidhyalakshmi","last_name":"Sridharan"},{"last_name":"Uttarkabat","first_name":"Motilal","contributor_type":"researcher"},{"last_name":"Jaroniec","first_name":"Christopher","contributor_type":"researcher"},{"last_name":"Ernst","contributor_type":"researcher","first_name":"Matthias"},{"orcid":"0000-0001-8729-7326","contributor_type":"researcher","first_name":"Petra","last_name":"Rovo","id":"c316e53f-b965-11eb-b128-bb26acc59c00"}],"author":[{"full_name":"Tatman, Benjamin","id":"71cda2f3-e604-11ee-a1df-da10587eda3f","last_name":"Tatman","first_name":"Benjamin"}],"date_created":"2025-05-14T10:46:07Z","related_material":{"link":[{"relation":"research_paper","url":"http.//doi.org/10.1021/jacs.5c09057","description":"Paper to which the dataset corresponds."}],"record":[{"status":"public","relation":"research_data","id":"20321"}]},"status":"public","date_updated":"2026-06-10T08:33:41Z","article_processing_charge":"No","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"department":[{"_id":"PaSc"}],"tmp":{"short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"type":"research_data"},{"isi":1,"abstract":[{"lang":"eng","text":"We demonstrate that gas disks around binary systems might deliver gas to the binary components only when the circumbinary disk is relatively warm. We present new grid-based hydrodynamics simulations, performed with the binary on the grid and a locally isothermal equation of state, in which the binary is seen to functionally \"stop accreting\" if the orbital Mach number in the disk exceeds a threshold value of about 40. Above this threshold, the disk continues to extract angular momentum from the binary orbit, but it delivers very little mass to the black holes and instead piles up mass in a ring surrounding the binary. This ring will eventually become viscously relaxed and deliver mass to the binary at the large-scale inflow rate. However, we show that the timescale for such relaxation can far exceed the implied binary lifetime. We demonstrate that the ability of a binary–disk system to equilibrate is dependent on the efficiency at which accretion streams deposit mass onto the binary, which, in turn is highly sensitive to the thermodynamic conditions of the inner disk. If disks around massive black hole binaries do operate in such nonaccreting regimes, it suggests these systems may be dimmer than their single black hole counterparts but could exhibit dramatic rebrightening after the black holes inspiral and merge. This dimming begins in the UV/optical and could completely choke high-energy emission, such that these systems would likely be intrinsically X-ray weak with reddened continua, potentially resembling the spectra of \"little red dots\" recently identified in JWST observations."}],"file":[{"success":1,"file_size":1058601,"file_name":"2025_AstrophysicalJour_Tiede.pdf","creator":"dernst","date_updated":"2025-05-19T07:20:30Z","date_created":"2025-05-19T07:20:30Z","access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"19708","checksum":"0d4c57ee944599c0789f3db467c5ca2f"}],"oa_version":"Published Version","language":[{"iso":"eng"}],"external_id":{"isi":["001483889000001"],"arxiv":["2410.03830"]},"volume":984,"year":"2025","department":[{"_id":"ZoHa"}],"intvolume":"       984","_id":"19699","date_updated":"2026-02-16T12:42:56Z","status":"public","article_processing_charge":"Yes","publisher":"IOP Publishing","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"C.T. sincerely thanks Daniel J. D'Orazio for useful and illuminating discussions. This work was supported by the European Union's Horizon 2023 research and innovation program under Marie Sklodowska-Curie grant agreement No. 101148364, by Sapere Aude Starting grant No. 121587 through the Danish Independent Research Fund, by the LISA Preparatory Science Program (LPS) through NASA grant 80NSSC24K0440, and by NASA Astrophysics Theory Program (ATP) grant 80NSSC22K0822. Computation time for this work was supported through the NYU IT High Performance Computing resources as well as the Tycho supercomputer hosted at the SCIENCE HPC center at the University of Copenhagen.","oa":1,"ddc":["520"],"fulldoi":"https://doi.org/10.3847/1538-4357/adc727","OA_type":"gold","day":"09","scopus_import":"1","publication_status":"published","file_date_updated":"2025-05-19T07:20:30Z","date_published":"2025-05-09T00:00:00Z","article_type":"original","OA_place":"publisher","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","article_number":"144","month":"05","author":[{"full_name":"Tiede, Christopher","last_name":"Tiede","first_name":"Christopher"},{"full_name":"Zrake, Jonathan","last_name":"Zrake","first_name":"Jonathan"},{"full_name":"Macfadyen, Andrew","first_name":"Andrew","last_name":"Macfadyen"},{"first_name":"Zoltán","orcid":"0000-0003-3633-5403","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","last_name":"Haiman","full_name":"Haiman, Zoltán"}],"date_created":"2025-05-18T22:02:49Z","arxiv":1,"citation":{"ieee":"C. Tiede, J. Zrake, A. Macfadyen, and Z. Haiman, “Suppressed accretion onto massive black hole binaries surrounded by thin disks,” <i>The Astrophysical Journal</i>, vol. 984, no. 2. IOP Publishing, 2025.","apa":"Tiede, C., Zrake, J., Macfadyen, A., &#38; Haiman, Z. (2025). Suppressed accretion onto massive black hole binaries surrounded by thin disks. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/adc727\">https://doi.org/10.3847/1538-4357/adc727</a>","ama":"Tiede C, Zrake J, Macfadyen A, Haiman Z. Suppressed accretion onto massive black hole binaries surrounded by thin disks. <i>The Astrophysical Journal</i>. 2025;984(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/adc727\">10.3847/1538-4357/adc727</a>","ista":"Tiede C, Zrake J, Macfadyen A, Haiman Z. 2025. Suppressed accretion onto massive black hole binaries surrounded by thin disks. The Astrophysical Journal. 984(2), 144.","mla":"Tiede, Christopher, et al. “Suppressed Accretion onto Massive Black Hole Binaries Surrounded by Thin Disks.” <i>The Astrophysical Journal</i>, vol. 984, no. 2, 144, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-4357/adc727\">10.3847/1538-4357/adc727</a>.","short":"C. Tiede, J. Zrake, A. Macfadyen, Z. Haiman, The Astrophysical Journal 984 (2025).","chicago":"Tiede, Christopher, Jonathan Zrake, Andrew Macfadyen, and Zoltán Haiman. “Suppressed Accretion onto Massive Black Hole Binaries Surrounded by Thin Disks.” <i>The Astrophysical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-4357/adc727\">https://doi.org/10.3847/1538-4357/adc727</a>."},"publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"doi":"10.3847/1538-4357/adc727","title":"Suppressed accretion onto massive black hole binaries surrounded by thin disks","DOAJ_listed":"1","publication":"The Astrophysical Journal","issue":"2","quality_controlled":"1"},{"has_accepted_license":"1","publisher":"IOP Publishing","oa":1,"ddc":["520"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"B.W. and J.L. acknowledge support from JWST-GO-04233.009-A. R.L.D. is supported by the Australian Research Council through the Discovery Early Career Researcher Award (DECRA) Fellowship DE240100136 funded by the Australian Government. T.B.M. was supported by a CIERA postdoctoral fellowship. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. This research was supported by the International Space Science Institute (ISSI) in Bern, through ISSI International Team project #562 (First Light at Cosmic Dawn: Exploiting the James Webb Space Telescope Revolution). The JWST data presented in this article were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. The specific observations analyzed here can be accessed via DOI:10.17909/c3t4-9p39. Computations for this research were performed on the Pennsylvania State University's Institute for Computational and Data Sciences' Roar supercomputer. This publication made use of the NASA Astrophysical Data System for bibliographic information.","abstract":[{"text":"The JWST discovery of \"little red dots\" (LRDs) is reshaping our picture of the early Universe, yet the physical mechanisms driving their compact size and UV-optical colors remain elusive. Here, we report an unusually bright LRD (zspec = 3.1) observed as part of the RUBIES program. This LRD exhibits broad emission lines (FWHM ∼ 4000 km s−1), a blue UV continuum, a clear Balmer break, and a red continuum sampled out to rest-frame 4 μm with MIRI. We develop a new joint galaxy and active galactic nucleus (AGN) model within the Prospector Bayesian inference framework and perform spectrophotometric modeling using NIRCam, MIRI, and NIRSpec/Prism observations. Our fiducial model reveals a M* ∼ 109 M⊙ galaxy alongside a dust-reddened AGN driving the optical emission. Explaining the rest-frame optical color as a reddened AGN requires AV ≳ 3, suggesting that a great majority of the accretion disk energy is reradiated as dust emission. Yet, despite clear AGN signatures, we find a surprising lack of hot torus emission, which implies that either the dust emission in this object must be cold, or the red continuum must instead be driven by a massive, evolved stellar population of the host galaxy—seemingly inconsistent with the high-EW broad lines (Hα rest-frame EW ∼ 800 Å). The widths and luminosities of Pa-β, Pa-δ, Pa-γ, and Hα imply a modest black hole mass of MBH ∼ 108 M⊙. Additionally, we identify a narrow blueshifted He i λ 1.083 μm absorption feature in NIRSpec/G395M spectra, signaling an ionized outflow with kinetic energy up to ∼1% the luminosity of the AGN. The low redshift of RUBIES-BLAGN-1, combined with the depth and richness of the JWST imaging and spectroscopic observations, provides a unique opportunity to build a physical model for these so-far mysterious LRDs, which may prove to be a crucial phase in the early formation of massive galaxies and their supermassive black holes.","lang":"eng"}],"file":[{"file_name":"2025_AstrophysicalJour_Wang.pdf","success":1,"file_size":3522072,"creator":"dernst","date_updated":"2025-05-19T07:08:39Z","date_created":"2025-05-19T07:08:39Z","access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"19707","checksum":"1a9ff4516d11808bc6947744473c9fc2"}],"isi":1,"external_id":{"arxiv":["2403.02304"],"isi":["001481589300001"]},"volume":984,"year":"2025","oa_version":"Published Version","language":[{"iso":"eng"}],"intvolume":"       984","department":[{"_id":"JoMa"}],"status":"public","date_updated":"2026-02-16T12:42:43Z","article_processing_charge":"Yes","_id":"19700","doi":"10.3847/1538-4357/adc1ca","arxiv":1,"citation":{"apa":"Wang, B., De Graaff, A., Davies, R. L., Greene, J. E., Leja, J., Brammer, G. B., … Whitaker, K. E. (2025). RUBIES: JWST/NIRSpec confirmation of an infrared-luminous, broad-line Little Red Dot with an ionized outflow. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/adc1ca\">https://doi.org/10.3847/1538-4357/adc1ca</a>","ista":"Wang B, De Graaff A, Davies RL, Greene JE, Leja J, Brammer GB, Goulding AD, Miller TB, Suess KA, Weibel A, Williams CC, Bezanson R, Boogaard LA, Cleri NJ, Hirschmann M, Katz H, Labbé I, Maseda MV, Matthee JJ, Mcconachie I, Naidu RP, Oesch PA, Rix HW, Setton DJ, Whitaker KE. 2025. RUBIES: JWST/NIRSpec confirmation of an infrared-luminous, broad-line Little Red Dot with an ionized outflow. The Astrophysical Journal. 984(2), 121.","ama":"Wang B, De Graaff A, Davies RL, et al. RUBIES: JWST/NIRSpec confirmation of an infrared-luminous, broad-line Little Red Dot with an ionized outflow. <i>The Astrophysical Journal</i>. 2025;984(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/adc1ca\">10.3847/1538-4357/adc1ca</a>","mla":"Wang, Bingjie, et al. “RUBIES: JWST/NIRSpec Confirmation of an Infrared-Luminous, Broad-Line Little Red Dot with an Ionized Outflow.” <i>The Astrophysical Journal</i>, vol. 984, no. 2, 121, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-4357/adc1ca\">10.3847/1538-4357/adc1ca</a>.","ieee":"B. Wang <i>et al.</i>, “RUBIES: JWST/NIRSpec confirmation of an infrared-luminous, broad-line Little Red Dot with an ionized outflow,” <i>The Astrophysical Journal</i>, vol. 984, no. 2. IOP Publishing, 2025.","chicago":"Wang, Bingjie, Anna De Graaff, Rebecca L. Davies, Jenny E. Greene, Joel Leja, Gabriel B. Brammer, Andy D. Goulding, et al. “RUBIES: JWST/NIRSpec Confirmation of an Infrared-Luminous, Broad-Line Little Red Dot with an Ionized Outflow.” <i>The Astrophysical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-4357/adc1ca\">https://doi.org/10.3847/1538-4357/adc1ca</a>.","short":"B. Wang, A. De Graaff, R.L. Davies, J.E. Greene, J. Leja, G.B. Brammer, A.D. Goulding, T.B. Miller, K.A. Suess, A. Weibel, C.C. Williams, R. Bezanson, L.A. Boogaard, N.J. Cleri, M. Hirschmann, H. Katz, I. Labbé, M.V. Maseda, J.J. Matthee, I. Mcconachie, R.P. Naidu, P.A. Oesch, H.W. Rix, D.J. Setton, K.E. Whitaker, The Astrophysical Journal 984 (2025)."},"publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"DOAJ_listed":"1","publication":"The Astrophysical Journal","title":"RUBIES: JWST/NIRSpec confirmation of an infrared-luminous, broad-line Little Red Dot with an ionized outflow","quality_controlled":"1","issue":"2","scopus_import":"1","date_published":"2025-05-09T00:00:00Z","publication_status":"published","article_type":"original","file_date_updated":"2025-05-19T07:08:39Z","fulldoi":"https://doi.org/10.3847/1538-4357/adc1ca","OA_type":"gold","day":"09","OA_place":"publisher","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","date_created":"2025-05-18T22:02:49Z","article_number":"121","month":"05","author":[{"full_name":"Wang, Bingjie","last_name":"Wang","first_name":"Bingjie"},{"full_name":"De Graaff, Anna","last_name":"De Graaff","first_name":"Anna"},{"last_name":"Davies","first_name":"Rebecca L.","full_name":"Davies, Rebecca L."},{"last_name":"Greene","first_name":"Jenny E.","full_name":"Greene, Jenny E."},{"last_name":"Leja","first_name":"Joel","full_name":"Leja, Joel"},{"last_name":"Brammer","first_name":"Gabriel B.","full_name":"Brammer, Gabriel B."},{"first_name":"Andy D.","last_name":"Goulding","full_name":"Goulding, Andy D."},{"full_name":"Miller, Tim B.","last_name":"Miller","first_name":"Tim B."},{"full_name":"Suess, Katherine A.","first_name":"Katherine A.","last_name":"Suess"},{"full_name":"Weibel, Andrea","last_name":"Weibel","first_name":"Andrea"},{"first_name":"Christina C.","last_name":"Williams","full_name":"Williams, Christina C."},{"full_name":"Bezanson, Rachel","first_name":"Rachel","last_name":"Bezanson"},{"last_name":"Boogaard","first_name":"Leindert A.","full_name":"Boogaard, Leindert A."},{"first_name":"Nikko J.","last_name":"Cleri","full_name":"Cleri, Nikko J."},{"last_name":"Hirschmann","first_name":"Michaela","full_name":"Hirschmann, Michaela"},{"full_name":"Katz, Harley","last_name":"Katz","first_name":"Harley"},{"last_name":"Labbé","first_name":"Ivo","full_name":"Labbé, Ivo"},{"last_name":"Maseda","first_name":"Michael V.","full_name":"Maseda, Michael V."},{"full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","last_name":"Matthee","orcid":"0000-0003-2871-127X","first_name":"Jorryt J"},{"last_name":"Mcconachie","first_name":"Ian","full_name":"Mcconachie, Ian"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"last_name":"Oesch","first_name":"Pascal A.","full_name":"Oesch, Pascal A."},{"last_name":"Rix","first_name":"Hans Walter","full_name":"Rix, Hans Walter"},{"last_name":"Setton","first_name":"David J.","full_name":"Setton, David J."},{"full_name":"Whitaker, Katherine E.","first_name":"Katherine E.","last_name":"Whitaker"}]},{"ddc":["530","510"],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"Thanks belong to Johannes Ageskov and Matˇej Tuˇsek for helpful discussions on some technical details. M. F. would further like to acknowledge support for research on this paper from the European Unions Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 101034413 as well as support by funding from Villum Fonden through the QMATH Centreof Excellence Grant No. 10059. D. K. was supported by the EXPRO Grant No.20-17749X of the Czech Science Foundation (GACR).","has_accepted_license":"1","publisher":"World Scientific Publishing","intvolume":"        37","department":[{"_id":"RoSe"}],"status":"public","date_updated":"2026-05-06T13:03:25Z","article_processing_charge":"Yes (in subscription journal)","_id":"19705","abstract":[{"lang":"eng","text":"A maximal realization of the two-dimensional Pauli operator, subject to Aharonov–Bohm magnetic field, is investigated. Contrary to the case of the Pauli operator with regular magnetic potentials, it is shown that both components of the Pauli operator are critical. Asymptotics of the weakly coupled eigenvalues, generated by electric (not necessarily self-adjoint) perturbations, are derived."}],"file":[{"checksum":"559d97ee2da28bf0bd2c6af507f3a914","content_type":"application/pdf","file_id":"20893","relation":"main_file","access_level":"open_access","date_updated":"2025-12-30T08:23:12Z","date_created":"2025-12-30T08:23:12Z","creator":"dernst","success":1,"file_size":484646,"file_name":"2025_ReviewsMathPhysics_Fialova.pdf"}],"project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"isi":1,"external_id":{"arxiv":["2501.17029"],"isi":["001481012500001"]},"volume":37,"year":"2025","oa_version":"Published Version","language":[{"iso":"eng"}],"quality_controlled":"1","issue":"6","doi":"10.1142/S0129055X25500114","arxiv":1,"publication_identifier":{"issn":["0129-055X"],"eissn":["1793-6659"]},"citation":{"short":"M. Fialova, D. Krejčiřík, Reviews in Mathematical Physics 37 (2025).","chicago":"Fialova, Marie, and David Krejčiřík. “Virtual Bound States of the Pauli Operator with an Aharonov–Bohm Potential.” <i>Reviews in Mathematical Physics</i>. World Scientific Publishing, 2025. <a href=\"https://doi.org/10.1142/S0129055X25500114\">https://doi.org/10.1142/S0129055X25500114</a>.","ieee":"M. Fialova and D. Krejčiřík, “Virtual bound states of the Pauli operator with an Aharonov–Bohm potential,” <i>Reviews in Mathematical Physics</i>, vol. 37, no. 6. World Scientific Publishing, 2025.","ista":"Fialova M, Krejčiřík D. 2025. Virtual bound states of the Pauli operator with an Aharonov–Bohm potential. Reviews in Mathematical Physics. 37(6), 2550011.","ama":"Fialova M, Krejčiřík D. Virtual bound states of the Pauli operator with an Aharonov–Bohm potential. <i>Reviews in Mathematical Physics</i>. 2025;37(6). doi:<a href=\"https://doi.org/10.1142/S0129055X25500114\">10.1142/S0129055X25500114</a>","apa":"Fialova, M., &#38; Krejčiřík, D. (2025). Virtual bound states of the Pauli operator with an Aharonov–Bohm potential. <i>Reviews in Mathematical Physics</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0129055X25500114\">https://doi.org/10.1142/S0129055X25500114</a>","mla":"Fialova, Marie, and David Krejčiřík. “Virtual Bound States of the Pauli Operator with an Aharonov–Bohm Potential.” <i>Reviews in Mathematical Physics</i>, vol. 37, no. 6, 2550011, World Scientific Publishing, 2025, doi:<a href=\"https://doi.org/10.1142/S0129055X25500114\">10.1142/S0129055X25500114</a>."},"APC_amount":"2320,48 EUR","publication":"Reviews in Mathematical Physics","title":"Virtual bound states of the Pauli operator with an Aharonov–Bohm potential","ec_funded":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","date_created":"2025-05-18T22:02:51Z","article_number":"2550011","month":"07","author":[{"full_name":"Fialova, Marie","first_name":"Marie","id":"e9c9844d-9e21-11ec-b482-f96fc09f7c4d","last_name":"Fialova"},{"full_name":"Krejčiřík, David","first_name":"David","last_name":"Krejčiřík"}],"scopus_import":"1","date_published":"2025-07-01T00:00:00Z","file_date_updated":"2025-12-30T08:23:12Z","publication_status":"published","article_type":"original","fulldoi":"https://doi.org/10.1142/S0129055X25500114","OA_type":"hybrid","day":"01","OA_place":"publisher","PlanS_conform":"1"},{"intvolume":"     15606","department":[{"_id":"KrPi"}],"date_updated":"2025-05-28T06:12:39Z","status":"public","article_processing_charge":"No","_id":"19712","page":"385-415","abstract":[{"text":"We study recent algebraic attacks (Briaud-Øygarden EC’23) on the Regular Syndrome Decoding (RSD) problem and the assumptions underlying the correctness of their attacks’ complexity estimates. By relating these assumptions to interesting algebraic-combinatorial problems, we prove that they do not hold in full generality. However, we show that they are (asymptotically) true for most parameter sets, supporting the soundness of algebraic attacks on RSD. Further, we prove—without any heuristics or assumptions—that RSD can be broken in polynomial time whenever the number of error blocks times the square of the size of error blocks is larger than 2 times the square of the dimension of the code.\r\nAdditionally, we use our methodology to attack a variant of the Learning With Errors problem where each error term lies in a fixed set of constant size. We prove that this problem can be broken in polynomial time, given a sufficient number of samples. This result improves on the seminal work by Arora and Ge (ICALP’11), as the attack’s time complexity is independent of the LWE modulus.","lang":"eng"}],"corr_author":"1","conference":{"end_date":"2025-05-08","start_date":"2025-05-04","location":"Madrid, Spain","name":"EUROCRYPT: International Conference on the Theory and Applications of Cryptographic Techniques"},"year":"2025","volume":15606,"oa_version":"Submitted Version","language":[{"iso":"eng"}],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank Pierre Briaud and Morten Øygarden for helpful discussions on algebraic attacks on RSD, and the EC reviewers for helpful comments.","alternative_title":["LNCS"],"publisher":"Springer Nature","type":"conference","date_created":"2025-05-19T14:15:01Z","month":"04","author":[{"last_name":"Cueto Noval","id":"ffc563a3-f6e0-11ea-865d-e3cce03d17cc","orcid":"0000-0002-2505-4246","first_name":"Miguel","full_name":"Cueto Noval, Miguel"},{"first_name":"Simon-Philipp","last_name":"Merz","full_name":"Merz, Simon-Philipp"},{"full_name":"Stählin, Patrick","first_name":"Patrick","last_name":"Stählin"},{"id":"f6b56fb6-dc63-11ee-9dbf-f6780863a85a","last_name":"Ünal","first_name":"Akin","orcid":"0000-0002-8929-0221","full_name":"Ünal, Akin"}],"scopus_import":"1","date_published":"2025-04-28T00:00:00Z","publication_status":"published","fulldoi":"https://doi.org/10.1007/978-3-031-91095-1_14","OA_type":"green","day":"28","OA_place":"repository","quality_controlled":"1","doi":"10.1007/978-3-031-91095-1_14","citation":{"short":"M. Cueto Noval, S.-P. Merz, P. Stählin, A. Ünal, in:, 44th Annual International Conference on the Theory and Applications of Cryptographic Techniques, Springer Nature, 2025, pp. 385–415.","chicago":"Cueto Noval, Miguel, Simon-Philipp Merz, Patrick Stählin, and Akin Ünal. “On the Soundness of Algebraic Attacks against Code-Based Assumptions.” In <i>44th Annual International Conference on the Theory and Applications of Cryptographic Techniques</i>, 15606:385–415. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-031-91095-1_14\">https://doi.org/10.1007/978-3-031-91095-1_14</a>.","ieee":"M. Cueto Noval, S.-P. Merz, P. Stählin, and A. Ünal, “On the soundness of algebraic attacks against code-based assumptions,” in <i>44th Annual International Conference on the Theory and Applications of Cryptographic Techniques</i>, Madrid, Spain, 2025, vol. 15606, pp. 385–415.","mla":"Cueto Noval, Miguel, et al. “On the Soundness of Algebraic Attacks against Code-Based Assumptions.” <i>44th Annual International Conference on the Theory and Applications of Cryptographic Techniques</i>, vol. 15606, Springer Nature, 2025, pp. 385–415, doi:<a href=\"https://doi.org/10.1007/978-3-031-91095-1_14\">10.1007/978-3-031-91095-1_14</a>.","apa":"Cueto Noval, M., Merz, S.-P., Stählin, P., &#38; Ünal, A. (2025). On the soundness of algebraic attacks against code-based assumptions. In <i>44th Annual International Conference on the Theory and Applications of Cryptographic Techniques</i> (Vol. 15606, pp. 385–415). Madrid, Spain: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-91095-1_14\">https://doi.org/10.1007/978-3-031-91095-1_14</a>","ista":"Cueto Noval M, Merz S-P, Stählin P, Ünal A. 2025. On the soundness of algebraic attacks against code-based assumptions. 44th Annual International Conference on the Theory and Applications of Cryptographic Techniques. EUROCRYPT: International Conference on the Theory and Applications of Cryptographic Techniques, LNCS, vol. 15606, 385–415.","ama":"Cueto Noval M, Merz S-P, Stählin P, Ünal A. On the soundness of algebraic attacks against code-based assumptions. In: <i>44th Annual International Conference on the Theory and Applications of Cryptographic Techniques</i>. Vol 15606. Springer Nature; 2025:385-415. doi:<a href=\"https://doi.org/10.1007/978-3-031-91095-1_14\">10.1007/978-3-031-91095-1_14</a>"},"publication_identifier":{"eissn":["1611-3349"],"isbn":["9783031910944"],"eisbn":["9783031910951"],"issn":["0302-9743"]},"publication":"44th Annual International Conference on the Theory and Applications of Cryptographic Techniques","title":"On the soundness of algebraic attacks against code-based assumptions","main_file_link":[{"open_access":"1","url":"https://www.research-collection.ethz.ch/handle/20.500.11850/732894"}]},{"doi":"10.1609/aaai.v39i19.34290","citation":{"ieee":"S. Talaei, M. Ansaripour, G. Nadiradze, and D.-A. Alistarh, “Hybrid decentralized optimization: Leveraging both first- and zeroth-order optimizers for faster convergence,” <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, vol. 39, no. 19. Association for the Advancement of Artificial Intelligence, pp. 20778–20786, 2025.","mla":"Talaei, Shayan, et al. “Hybrid Decentralized Optimization: Leveraging Both First- and Zeroth-Order Optimizers for Faster Convergence.” <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>, vol. 39, no. 19, Association for the Advancement of Artificial Intelligence, 2025, pp. 20778–86, doi:<a href=\"https://doi.org/10.1609/aaai.v39i19.34290\">10.1609/aaai.v39i19.34290</a>.","ista":"Talaei S, Ansaripour M, Nadiradze G, Alistarh D-A. 2025. Hybrid decentralized optimization: Leveraging both first- and zeroth-order optimizers for faster convergence. Proceedings of the 39th AAAI Conference on Artificial Intelligence. 39(19), 20778–20786.","apa":"Talaei, S., Ansaripour, M., Nadiradze, G., &#38; Alistarh, D.-A. (2025). Hybrid decentralized optimization: Leveraging both first- and zeroth-order optimizers for faster convergence. <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>. Association for the Advancement of Artificial Intelligence. <a href=\"https://doi.org/10.1609/aaai.v39i19.34290\">https://doi.org/10.1609/aaai.v39i19.34290</a>","ama":"Talaei S, Ansaripour M, Nadiradze G, Alistarh D-A. Hybrid decentralized optimization: Leveraging both first- and zeroth-order optimizers for faster convergence. <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>. 2025;39(19):20778-20786. doi:<a href=\"https://doi.org/10.1609/aaai.v39i19.34290\">10.1609/aaai.v39i19.34290</a>","short":"S. Talaei, M. Ansaripour, G. Nadiradze, D.-A. Alistarh, Proceedings of the 39th AAAI Conference on Artificial Intelligence 39 (2025) 20778–20786.","chicago":"Talaei, Shayan, Matin Ansaripour, Giorgi Nadiradze, and Dan-Adrian Alistarh. “Hybrid Decentralized Optimization: Leveraging Both First- and Zeroth-Order Optimizers for Faster Convergence.” <i>Proceedings of the 39th AAAI Conference on Artificial Intelligence</i>. Association for the Advancement of Artificial Intelligence, 2025. <a href=\"https://doi.org/10.1609/aaai.v39i19.34290\">https://doi.org/10.1609/aaai.v39i19.34290</a>."},"publication_identifier":{"eissn":["2374-3468"],"issn":["2159-5399"]},"arxiv":1,"publication":"Proceedings of the 39th AAAI Conference on Artificial Intelligence","title":"Hybrid decentralized optimization: Leveraging both first- and zeroth-order optimizers for faster convergence","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1609/aaai.v39i19.34290"}],"quality_controlled":"1","issue":"19","publication_status":"published","article_type":"original","date_published":"2025-04-11T00:00:00Z","scopus_import":"1","OA_type":"free access","day":"11","fulldoi":"https://doi.org/10.1609/aaai.v39i19.34290","OA_place":"publisher","ec_funded":1,"type":"journal_article","date_created":"2025-05-19T14:15:35Z","author":[{"last_name":"Talaei","first_name":"Shayan","full_name":"Talaei, Shayan"},{"first_name":"Matin","last_name":"Ansaripour","full_name":"Ansaripour, Matin"},{"id":"3279A00C-F248-11E8-B48F-1D18A9856A87","last_name":"Nadiradze","orcid":"0000-0001-5634-0731","first_name":"Giorgi","full_name":"Nadiradze, Giorgi"},{"full_name":"Alistarh, Dan-Adrian","orcid":"0000-0003-3650-940X","first_name":"Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","last_name":"Alistarh"}],"month":"04","publisher":"Association for the Advancement of Artificial Intelligence","oa":1,"acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement\r\nNo 805223 ScaleML). The authors would like to acknowledge Eugenia Iofinova for useful discussions during the inception of this project.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Distributed optimization is the standard way of speeding up machine learning training, and most of the research in the area focuses on distributed first-order, gradient-based methods. Yet, there are settings where some computationally-bounded nodes may not be able to implement first-order, gradient-based optimization, while they could still contribute to joint optimization tasks. In this paper, we initiate the study of hybrid decentralized optimization, studying settings where nodes with zeroth-order and first-order optimization capabilities co-exist in a distributed system, and attempt to jointly solve an optimization task over some data distribution. We essentially show that, under reasonable parameter settings, such a system can not only withstand noisier zeroth-order agents but can even benefit from integrating such agents into the optimization process, rather than ignoring their information. At the core of our approach is a new analysis of distributed optimization with noisy and possibly-biased gradient estimators, which may be of independent interest. Our results hold for both convex and non-convex objectives. Experimental results on standard optimization tasks confirm our analysis, showing that hybrid first-zeroth order optimization can be practical, even when training deep neural networks.","lang":"eng"}],"corr_author":"1","project":[{"call_identifier":"H2020","_id":"268A44D6-B435-11E9-9278-68D0E5697425","grant_number":"805223","name":"Elastic Coordination for Scalable Machine Learning"}],"year":"2025","volume":39,"external_id":{"arxiv":["2210.07703"]},"language":[{"iso":"eng"}],"oa_version":"Preprint","intvolume":"        39","department":[{"_id":"DaAl"}],"article_processing_charge":"No","date_updated":"2026-02-16T12:34:44Z","status":"public","related_material":{"link":[{"url":"https://github.com/ShayanTalaei/HDO","relation":"software"}]},"page":"20778-20786","_id":"19713"},{"pmid":1,"quality_controlled":"1","publication":"Current Opinion in Neurobiology","title":"How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex","doi":"10.1016/j.conb.2025.103046","citation":{"chicago":"Pipicelli, Fabrizia, Ana Villalba Requena, and Simon Hippenmeyer. “How Radial Glia Progenitor Lineages Generate Cell-Type Diversity in the Developing Cerebral Cortex.” <i>Current Opinion in Neurobiology</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.conb.2025.103046\">https://doi.org/10.1016/j.conb.2025.103046</a>.","short":"F. Pipicelli, A. Villalba Requena, S. Hippenmeyer, Current Opinion in Neurobiology 93 (2025).","mla":"Pipicelli, Fabrizia, et al. “How Radial Glia Progenitor Lineages Generate Cell-Type Diversity in the Developing Cerebral Cortex.” <i>Current Opinion in Neurobiology</i>, vol. 93, 103046, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.conb.2025.103046\">10.1016/j.conb.2025.103046</a>.","ista":"Pipicelli F, Villalba Requena A, Hippenmeyer S. 2025. How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex. Current Opinion in Neurobiology. 93, 103046.","apa":"Pipicelli, F., Villalba Requena, A., &#38; Hippenmeyer, S. (2025). How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.conb.2025.103046\">https://doi.org/10.1016/j.conb.2025.103046</a>","ama":"Pipicelli F, Villalba Requena A, Hippenmeyer S. How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex. <i>Current Opinion in Neurobiology</i>. 2025;93. doi:<a href=\"https://doi.org/10.1016/j.conb.2025.103046\">10.1016/j.conb.2025.103046</a>","ieee":"F. Pipicelli, A. Villalba Requena, and S. Hippenmeyer, “How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex,” <i>Current Opinion in Neurobiology</i>, vol. 93. Elsevier, 2025."},"publication_identifier":{"issn":["0959-4388"]},"date_created":"2025-05-20T10:20:09Z","author":[{"full_name":"Pipicelli, Fabrizia","first_name":"Fabrizia","last_name":"Pipicelli","id":"649134fd-d012-11ed-8f82-db1e5050f9ba"},{"first_name":"Ana","orcid":"0000-0002-5615-5277","last_name":"Villalba Requena","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","full_name":"Villalba Requena, Ana"},{"full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061","first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer"}],"month":"08","article_number":"103046","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"PlanS_conform":"1","OA_place":"publisher","article_type":"original","date_published":"2025-08-01T00:00:00Z","publication_status":"published","file_date_updated":"2025-12-30T08:25:49Z","scopus_import":"1","OA_type":"hybrid","day":"01","fulldoi":"https://doi.org/10.1016/j.conb.2025.103046","oa":1,"ddc":["570"],"acknowledgement":"We wish to thank all members of the Hippenmeyer laboratory at ISTA for exciting discussions on the subject of this review. We apologize to colleagues whose work we could not cite and/or discuss in the frame of the available space. Work in the Hippenmeyer laboratory on the discussed topic is supported by ISTA institutional funds, an EMBO LTF (ALTF 994–2023) to F.P, and FWF SFB F78 to S.H.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Elsevier","has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","status":"public","date_updated":"2025-12-30T10:54:14Z","_id":"19718","intvolume":"        93","department":[{"_id":"SiHi"}],"volume":93,"year":"2025","external_id":{"isi":["001496227000001"],"pmid":["40383049"]},"language":[{"iso":"eng"}],"oa_version":"Published Version","file":[{"file_name":"2025_CurrentOpNeurobiology_Pipicelli.pdf","success":1,"file_size":1592649,"creator":"dernst","date_created":"2025-12-30T08:25:49Z","date_updated":"2025-12-30T08:25:49Z","access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_id":"20894","checksum":"05bacb4acbe6275d43e873dec9ba1d52"}],"abstract":[{"lang":"eng","text":"The cerebral cortex is arguably the most complex organ in humans. The cortical architecture is characterized by a remarkable diversity of neuronal and glial cell types that make up its neuronal circuits. Following a precise temporally ordered program, radial glia progenitor (RGP) cells generate all cortical excitatory projection neurons and glial cell-types. Cortical excitatory projection neurons are produced either directly or via intermediate progenitors, through indirect neurogenesis. How the extensive cortical cell-type diversity is generated during cortex development remains, however, a fundamental open question. How do RGPs quantitatively and qualitatively generate all the neocortical neurons? How does direct and indirect neurogenesis contribute to the establishment of neuronal and lineage heterogeneity? Whether RGPs represent a homogeneous and/or multipotent progenitor population, or if RGPs consist of heterogeneous groups is currently also not known. In this review, we will summarize the latest findings that contributed to a deeper insight into the above key questions."}],"corr_author":"1","project":[{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","grant_number":"F7805","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression"},{"_id":"7c084566-9f16-11ee-852c-c88a1dbbf1cf","grant_number":"ALTF 994-2023","name":"Role of cell lineage in generating cell-type diversity in developing neocortex’"}],"isi":1},{"publication":"Journal of Molecular Biology","title":"A F420-dependent single domain chemogenetic tool for protein de-dimerization","doi":"10.1016/j.jmb.2025.169184","publication_identifier":{"eissn":["1089-8638"],"issn":["0022-2836"]},"citation":{"ista":"Antoney J, Kainrath S, Dubowsky JG, Ahmed FH, Kang SW, Mackie ERR, Bracho Granado G, Soares Da Costa TP, Jackson CJ, Janovjak HL. 2025. A F420-dependent single domain chemogenetic tool for protein de-dimerization. Journal of Molecular Biology. 437(17), 169184.","apa":"Antoney, J., Kainrath, S., Dubowsky, J. G., Ahmed, F. H., Kang, S. W., Mackie, E. R. R., … Janovjak, H. L. (2025). A F420-dependent single domain chemogenetic tool for protein de-dimerization. <i>Journal of Molecular Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jmb.2025.169184\">https://doi.org/10.1016/j.jmb.2025.169184</a>","ama":"Antoney J, Kainrath S, Dubowsky JG, et al. A F420-dependent single domain chemogenetic tool for protein de-dimerization. <i>Journal of Molecular Biology</i>. 2025;437(17). doi:<a href=\"https://doi.org/10.1016/j.jmb.2025.169184\">10.1016/j.jmb.2025.169184</a>","mla":"Antoney, James, et al. “A F420-Dependent Single Domain Chemogenetic Tool for Protein de-Dimerization.” <i>Journal of Molecular Biology</i>, vol. 437, no. 17, 169184, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.jmb.2025.169184\">10.1016/j.jmb.2025.169184</a>.","ieee":"J. Antoney <i>et al.</i>, “A F420-dependent single domain chemogenetic tool for protein de-dimerization,” <i>Journal of Molecular Biology</i>, vol. 437, no. 17. Elsevier, 2025.","chicago":"Antoney, James, Stephanie Kainrath, Joshua G. Dubowsky, F. Hafna Ahmed, Suk Woo Kang, Emily R.R. Mackie, Gustavo Bracho Granado, Tatiana P. Soares Da Costa, Colin J. Jackson, and Harald L Janovjak. “A F420-Dependent Single Domain Chemogenetic Tool for Protein de-Dimerization.” <i>Journal of Molecular Biology</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.jmb.2025.169184\">https://doi.org/10.1016/j.jmb.2025.169184</a>.","short":"J. Antoney, S. Kainrath, J.G. Dubowsky, F.H. Ahmed, S.W. Kang, E.R.R. Mackie, G. Bracho Granado, T.P. Soares Da Costa, C.J. Jackson, H.L. Janovjak, Journal of Molecular Biology 437 (2025)."},"quality_controlled":"1","pmid":1,"issue":"17","OA_place":"publisher","PlanS_conform":"1","scopus_import":"1","publication_status":"published","article_type":"original","date_published":"2025-09-01T00:00:00Z","file_date_updated":"2025-12-30T08:18:07Z","fulldoi":"https://doi.org/10.1016/j.jmb.2025.169184","OA_type":"hybrid","day":"01","date_created":"2025-05-25T22:16:39Z","month":"09","article_number":"169184","author":[{"full_name":"Antoney, James","first_name":"James","last_name":"Antoney"},{"first_name":"Stephanie","orcid":"0000-0002-6709-2195","last_name":"Kainrath","id":"32CFBA64-F248-11E8-B48F-1D18A9856A87","full_name":"Kainrath, Stephanie"},{"last_name":"Dubowsky","first_name":"Joshua G.","full_name":"Dubowsky, Joshua G."},{"first_name":"F. Hafna","last_name":"Ahmed","full_name":"Ahmed, F. Hafna"},{"last_name":"Kang","first_name":"Suk Woo","full_name":"Kang, Suk Woo"},{"first_name":"Emily R.R.","last_name":"Mackie","full_name":"Mackie, Emily R.R."},{"first_name":"Gustavo","last_name":"Bracho Granado","full_name":"Bracho Granado, Gustavo"},{"full_name":"Soares Da Costa, Tatiana P.","first_name":"Tatiana P.","last_name":"Soares Da Costa"},{"full_name":"Jackson, Colin J.","first_name":"Colin J.","last_name":"Jackson"},{"id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","last_name":"Janovjak","first_name":"Harald L","orcid":"0000-0002-8023-9315","full_name":"Janovjak, Harald L"}],"type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"has_accepted_license":"1","publisher":"Elsevier","ddc":["570"],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank J. Kaczmarski for advice on isothermal titration calorimetry and helpful comments, and Alexandra Tichy, Elliot Gerrard and Rahkesh T Sabapathy for assistance with experiments. This study was supported by grants of the Australian Research Council (FT200100519 and DP200102093, to H.J.; DE190100806, DP220101901, FT230100203, and DP250102939 to T.P.S.D.C; DP200102093, CE200100029 and CE200100012 to C.J.J.), the National Health and Medical Research Council (APP1187638, to H.J.). S.K. was supported by the graduate program MolecularDrugTargets (Austrian Science Fund FWF W1232). The Australian Regenerative Medicine Institute is supported by grants from the State Government of Victoria and the Australian Government. The EMBL Australia Partnership Laboratory (EMBL Australia) is supported by the National Collaborative Research Infrastructure Strategy (NCRIS) of the Australian Government. T.P.S.D.C. acknowledges the University of Adelaide for a Future Making Fellowship. E.R.R.M acknowledges the Grains Research and Development Corporation (9176977) for support through a PhD scholarship and operational funding. J.A. and E.R.R.M. were supported by Australian Research Training Program scholarship. MicroMon of Monash University provided Sanger sequencing services. Imaging was performed in the CellScreen SA screening center of Flinders University. C.J.J. thanks the ARC Centre of Excellence for Innovations in Peptide and Protein Science and the ARC Centre of Excellence in Synthetic Biology. We thank the staff of the MX2 beamline at the Australian Synchrotron, part of ANSTO, which made use of the Australian Cancer Research Foundation (ACRF) detector.","external_id":{"pmid":["40324743"],"isi":["001494762800001"]},"year":"2025","volume":437,"oa_version":"Published Version","language":[{"iso":"eng"}],"abstract":[{"text":"Protein-protein interactions (PPIs) mediate many fundamental cellular processes. Control of PPIs through optically or chemically responsive protein domains has had a profound impact on basic research and some clinical applications. Most chemogenetic methods induce the association, i.e., dimerization or oligomerization, of target proteins, whilst the few available dissociation approaches either break large oligomeric protein clusters or heteromeric complexes. Here, we have exploited the controlled dissociation of a homodimeric oxidoreductase from mycobacteria (MSMEG_2027) by its native cofactor, F420, which is not present in mammals, as a bioorthogonal monomerization switch. Using X-ray crystallography, we found that in the absence of F420 MSMEG_2027 forms a unique domain-swapped dimer that occludes the cofactor binding site. Rearrangement of the N-terminal helix upon F420 binding results in the dissolution of the dimer. We then showed that MSMEG_2027 can be fused to proteins of interest in human cells and applied it as a tool to induce and release MAPK/ERK signalling downstream of a chimeric fibroblast growth factor receptor 1 (FGFR1) tyrosine kinase. This F420-dependent chemogenetic de-homodimerization tool is stoichiometric and based on a single domain and thus represents a novel mechanism to investigate protein complexes in situ.","lang":"eng"}],"file":[{"content_type":"application/pdf","file_id":"20892","checksum":"fb6e84ba7dc92faee97647fd2bc8cca8","access_level":"open_access","relation":"main_file","creator":"dernst","date_updated":"2025-12-30T08:18:07Z","date_created":"2025-12-30T08:18:07Z","file_name":"2025_JourMolecularBiology_Antoney.pdf","success":1,"file_size":1682721}],"isi":1,"project":[{"_id":"255A6082-B435-11E9-9278-68D0E5697425","name":"Molecular Drug Targets","grant_number":"W1232-B24","call_identifier":"FWF"}],"status":"public","date_updated":"2025-12-30T08:18:25Z","article_processing_charge":"Yes (in subscription journal)","_id":"19725","intvolume":"       437","department":[{"_id":"CaGu"}]}]