---
_id: '15271'
abstract:
- lang: eng
  text: 'We settle the complexity of the (∆ + 1)-coloring and (∆ + 1)-list coloring
    problems intheCONGESTED CLIQUEmodel by presenting a simpledeterministicalgorithm
    for both problemsrunning in a constant number of rounds.  This matches the complexity
    of the recent breakthroughrandomizedconstant-round (∆ + 1)-list coloring algorithm
    due to Chang et al.  [Proceedings of the38th  ACM  Symposium  on  Principles  of  Distributed  Computing,  2019]  and  significantly  improvesupon
    the state-of-the-artO(log ∆)-round deterministic (∆ + 1)-coloring bound of Parter
    [Proceed-ings of the 45th Annual International Colloquium on Automata, Languages
    and Programming].  Aremarkable property of our algorithm is its simplicity.  Whereas
    the state-of-the-artrandomizedal-gorithms for this problem are based on the quite
    involved local coloring algorithm of Chang, Li, andPettie [Proceedings of the
    50th Annual ACM SIGACT Symposium on Theory of Computing, 2018],our algorithm can
    be described in just a few lines.  At a high level, it applies a careful derandomiza-tion
    of a recursive procedure which partitions the nodes and their respective palettes
    into separatebins.  We show that afterO(1) recursion steps, the remaining uncolored
    subgraph within each bin haslinear size and thus can be solved locally by collecting
    it to a single node.  This algorithm can alsobe implemented in the massively parallel
    computation (MPC) model provided that each machine haslinear (inn, the number
    of nodes in the input graph) space.  We also show an extension of our algo-rithm
    to theMPCregime, in which machines havesublinearspace:  we present the first deterministic(∆
    + 1)-list coloring algorithm designed for sublinear-spaceMPC, which runs inO(log
    ∆ + log logn)rounds.'
acknowledgement: The  first  author  was  partially  supported  by  the  Centre  for  Discrete  Mathematics
  and its Applications, by the IBM Faculty Award, and by the EPSRC award EP/N011163/1.  The
  second author was partially supported by the European Union’s Horizon 2020 research
  and innovation program under the Marie Sklodowska-Curie grant agreement 754411.  The
  first and third authors were partially supported by a Weizmann-UK Making Connections
  grant.
article_processing_charge: No
article_type: original
author:
- first_name: Artur
  full_name: Czumaj, Artur
  last_name: Czumaj
- first_name: Peter
  full_name: Davies, Peter
  id: 11396234-BB50-11E9-B24C-90FCE5697425
  last_name: Davies
  orcid: 0000-0002-5646-9524
- first_name: Merav
  full_name: Parter, Merav
  last_name: Parter
citation:
  ama: Czumaj A, Davies P, Parter M. Simple, deterministic, constant-round coloring
    in congested clique and MPC. <i>SIAM Journal on Computing</i>. 2021;50(5):1603-1626.
    doi:<a href="https://doi.org/10.1137/20m1366502">10.1137/20m1366502</a>
  apa: Czumaj, A., Davies, P., &#38; Parter, M. (2021). Simple, deterministic, constant-round
    coloring in congested clique and MPC. <i>SIAM Journal on Computing</i>. Society
    for Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/20m1366502">https://doi.org/10.1137/20m1366502</a>
  chicago: Czumaj, Artur, Peter Davies, and Merav Parter. “Simple, Deterministic,
    Constant-Round Coloring in Congested Clique and MPC.” <i>SIAM Journal on Computing</i>.
    Society for Industrial and Applied Mathematics, 2021. <a href="https://doi.org/10.1137/20m1366502">https://doi.org/10.1137/20m1366502</a>.
  ieee: A. Czumaj, P. Davies, and M. Parter, “Simple, deterministic, constant-round
    coloring in congested clique and MPC,” <i>SIAM Journal on Computing</i>, vol.
    50, no. 5. Society for Industrial and Applied Mathematics, pp. 1603–1626, 2021.
  ista: Czumaj A, Davies P, Parter M. 2021. Simple, deterministic, constant-round
    coloring in congested clique and MPC. SIAM Journal on Computing. 50(5), 1603–1626.
  mla: Czumaj, Artur, et al. “Simple, Deterministic, Constant-Round Coloring in Congested
    Clique and MPC.” <i>SIAM Journal on Computing</i>, vol. 50, no. 5, Society for
    Industrial and Applied Mathematics, 2021, pp. 1603–26, doi:<a href="https://doi.org/10.1137/20m1366502">10.1137/20m1366502</a>.
  short: A. Czumaj, P. Davies, M. Parter, SIAM Journal on Computing 50 (2021) 1603–1626.
date_created: 2024-04-03T07:53:22Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2025-09-10T10:14:11Z
day: '01'
department:
- _id: DaAl
doi: 10.1137/20m1366502
ec_funded: 1
external_id:
  isi:
  - '000713008600004'
intvolume: '        50'
isi: 1
issue: '5'
keyword:
- General Mathematics
- General Computer Science
language:
- iso: eng
month: '01'
oa_version: None
page: 1603-1626
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: SIAM Journal on Computing
publication_identifier:
  eissn:
  - 1095-7111
  issn:
  - 0097-5397
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simple, deterministic, constant-round coloring in congested clique and MPC
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 50
year: '2021'
...
---
_id: '15272'
abstract:
- lang: eng
  text: The assembly of neuronal circuits involves the migrations of neurons from
    their place of birth to their final location in the nervous system, as well as
    the coordinated growth and patterning of axons and dendrites. In screens for genes
    required for patterning of the nervous system, we identified the <jats:italic>catp-8/P5A-ATPase</jats:italic>
    as an important regulator of neural patterning. P5A-ATPases are part of the P-type
    ATPases, a family of proteins known to serve a conserved function as transporters
    of ions, lipids and polyamines in unicellular eukaryotes, plants, and humans.
    While the function of many P-type ATPases is relatively well understood, the function
    of P5A-ATPases in metazoans remained elusive. We show here, that the <jats:italic>Caenorhabditis
    elegans</jats:italic> ortholog <jats:italic>catp-8/P5A-ATPase</jats:italic> is
    required for defined aspects of nervous system development. Specifically, the
    <jats:italic>catp-8/P5A-ATPase</jats:italic> serves functions in shaping the elaborately
    sculpted dendritic trees of somatosensory PVD neurons. Moreover, <jats:italic>catp-8/P5A-ATPase</jats:italic>
    is required for axonal guidance and repulsion at the midline, as well as embryonic
    and postembryonic neuronal migrations. Interestingly, not all axons at the midline
    require <jats:italic>catp-8/P5A-ATPase</jats:italic>, although the axons run in
    the same fascicles and navigate the same space. Similarly, not all neuronal migrations
    require <jats:italic>catp-8/P5A-ATPase</jats:italic>. A CATP-8/P5A-ATPase reporter
    is localized to the ER in most, if not all, tissues and <jats:italic>catp-8/P5A-ATPase</jats:italic>
    can function both cell-autonomously and non-autonomously to regulate neuronal
    development. Genetic analyses establish that <jats:italic>catp-8/P5A-ATPase</jats:italic>
    can function in multiple pathways, including the Menorin pathway, previously shown
    to control dendritic patterning in PVD, and Wnt signaling, which functions to
    control neuronal migrations. Lastly, we show that <jats:italic>catp-8/P5A-ATPase</jats:italic>
    is required for localizing select transmembrane proteins necessary for dendrite
    morphogenesis. Collectively, our studies suggest that <jats:italic>catp-8/P5A-ATPase</jats:italic>
    serves diverse, yet specific, roles in different genetic pathways and may be involved
    in the regulation or localization of transmembrane and secreted proteins to specific
    subcellular compartments.
article_number: e1009475
article_processing_charge: No
article_type: original
author:
- first_name: Leo T. H.
  full_name: Tang, Leo T. H.
  last_name: Tang
- first_name: Meera
  full_name: Trivedi, Meera
  last_name: Trivedi
- first_name: Jenna
  full_name: Freund, Jenna
  last_name: Freund
- first_name: Christopher J.
  full_name: Salazar, Christopher J.
  last_name: Salazar
- first_name: Maisha
  full_name: Rahman, Maisha
  last_name: Rahman
- first_name: Nelson
  full_name: Ramirez, Nelson
  id: 39831956-E4FE-11E9-85DE-0DC7E5697425
  last_name: Ramirez
- first_name: Garrett
  full_name: Lee, Garrett
  last_name: Lee
- first_name: Yu
  full_name: Wang, Yu
  last_name: Wang
- first_name: Barth D.
  full_name: Grant, Barth D.
  last_name: Grant
- first_name: Hannes E.
  full_name: Bülow, Hannes E.
  last_name: Bülow
citation:
  ama: Tang LTH, Trivedi M, Freund J, et al. The CATP-8/P5A-type ATPase functions
    in multiple pathways during neuronal patterning. <i>PLOS Genetics</i>. 2021;17(7).
    doi:<a href="https://doi.org/10.1371/journal.pgen.1009475">10.1371/journal.pgen.1009475</a>
  apa: Tang, L. T. H., Trivedi, M., Freund, J., Salazar, C. J., Rahman, M., Ramirez,
    N., … Bülow, H. E. (2021). The CATP-8/P5A-type ATPase functions in multiple pathways
    during neuronal patterning. <i>PLOS Genetics</i>. Public Library of Science. <a
    href="https://doi.org/10.1371/journal.pgen.1009475">https://doi.org/10.1371/journal.pgen.1009475</a>
  chicago: Tang, Leo T. H., Meera Trivedi, Jenna Freund, Christopher J. Salazar, Maisha
    Rahman, Nelson Ramirez, Garrett Lee, Yu Wang, Barth D. Grant, and Hannes E. Bülow.
    “The CATP-8/P5A-Type ATPase Functions in Multiple Pathways during Neuronal Patterning.”
    <i>PLOS Genetics</i>. Public Library of Science, 2021. <a href="https://doi.org/10.1371/journal.pgen.1009475">https://doi.org/10.1371/journal.pgen.1009475</a>.
  ieee: L. T. H. Tang <i>et al.</i>, “The CATP-8/P5A-type ATPase functions in multiple
    pathways during neuronal patterning,” <i>PLOS Genetics</i>, vol. 17, no. 7. Public
    Library of Science, 2021.
  ista: Tang LTH, Trivedi M, Freund J, Salazar CJ, Rahman M, Ramirez N, Lee G, Wang
    Y, Grant BD, Bülow HE. 2021. The CATP-8/P5A-type ATPase functions in multiple
    pathways during neuronal patterning. PLOS Genetics. 17(7), e1009475.
  mla: Tang, Leo T. H., et al. “The CATP-8/P5A-Type ATPase Functions in Multiple Pathways
    during Neuronal Patterning.” <i>PLOS Genetics</i>, vol. 17, no. 7, e1009475, Public
    Library of Science, 2021, doi:<a href="https://doi.org/10.1371/journal.pgen.1009475">10.1371/journal.pgen.1009475</a>.
  short: L.T.H. Tang, M. Trivedi, J. Freund, C.J. Salazar, M. Rahman, N. Ramirez,
    G. Lee, Y. Wang, B.D. Grant, H.E. Bülow, PLOS Genetics 17 (2021).
date_created: 2024-04-03T07:57:12Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2024-04-10T08:57:16Z
day: '01'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1371/journal.pgen.1009475
external_id:
  pmid:
  - '34197450'
file:
- access_level: open_access
  checksum: 7352b195e4db6d404f702fe6ad8b55ad
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-10T08:53:43Z
  date_updated: 2024-04-10T08:53:43Z
  file_id: '15308'
  file_name: 2021_PlosGenetics_Tang.pdf
  file_size: 4224934
  relation: main_file
  success: 1
file_date_updated: 2024-04-10T08:53:43Z
has_accepted_license: '1'
intvolume: '        17'
issue: '7'
keyword:
- Cancer Research
- Genetics (clinical)
- Genetics
- Molecular Biology
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLOS Genetics
publication_identifier:
  issn:
  - 1553-7404
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
status: public
title: The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2021'
...
---
_id: '15273'
abstract:
- lang: eng
  text: Synapses of glutamatergic mossy fibers (MFs) onto cerebellar unipolar brush
    cells (UBCs) generate slow excitatory (ON) or inhibitory (OFF) postsynaptic responses
    dependent on the complement of glutamate receptors expressed on the UBC’s large
    dendritic brush. Using mouse brain slice recording and computational modeling
    of synaptic transmission, we found that substantial glutamate is maintained in
    the UBC synaptic cleft, sufficient to modify spontaneous firing in OFF UBCs and
    tonically desensitize AMPARs of ON UBCs. The source of this ambient glutamate
    was spontaneous, spike-independent exocytosis from the MF terminal, and its level
    was dependent on activity of glutamate transporters EAAT1–2. Increasing levels
    of ambient glutamate shifted the polarity of evoked synaptic responses in ON UBCs
    and altered the phase of responses to in vivo-like synaptic activity. Unlike classical
    fast synapses, receptors at the UBC synapse are virtually always exposed to a
    significant level of glutamate, which varies in a graded manner during transmission.
article_number: e63819
article_processing_charge: Yes
article_type: original
author:
- first_name: Timothy S
  full_name: Balmer, Timothy S
  last_name: Balmer
- first_name: Carolina
  full_name: Borges Merjane, Carolina
  id: 4305C450-F248-11E8-B48F-1D18A9856A87
  last_name: Borges Merjane
  orcid: 0000-0003-0005-401X
- first_name: Laurence O
  full_name: Trussell, Laurence O
  last_name: Trussell
citation:
  ama: Balmer TS, Borges Merjane C, Trussell LO. Incomplete removal of extracellular
    glutamate controls synaptic transmission and integration at a cerebellar synapse.
    <i>eLife</i>. 2021;10. doi:<a href="https://doi.org/10.7554/elife.63819">10.7554/elife.63819</a>
  apa: Balmer, T. S., Borges Merjane, C., &#38; Trussell, L. O. (2021). Incomplete
    removal of extracellular glutamate controls synaptic transmission and integration
    at a cerebellar synapse. <i>ELife</i>. eLife Sciences Publications. <a href="https://doi.org/10.7554/elife.63819">https://doi.org/10.7554/elife.63819</a>
  chicago: Balmer, Timothy S, Carolina Borges Merjane, and Laurence O Trussell. “Incomplete
    Removal of Extracellular Glutamate Controls Synaptic Transmission and Integration
    at a Cerebellar Synapse.” <i>ELife</i>. eLife Sciences Publications, 2021. <a
    href="https://doi.org/10.7554/elife.63819">https://doi.org/10.7554/elife.63819</a>.
  ieee: T. S. Balmer, C. Borges Merjane, and L. O. Trussell, “Incomplete removal of
    extracellular glutamate controls synaptic transmission and integration at a cerebellar
    synapse,” <i>eLife</i>, vol. 10. eLife Sciences Publications, 2021.
  ista: Balmer TS, Borges Merjane C, Trussell LO. 2021. Incomplete removal of extracellular
    glutamate controls synaptic transmission and integration at a cerebellar synapse.
    eLife. 10, e63819.
  mla: Balmer, Timothy S., et al. “Incomplete Removal of Extracellular Glutamate Controls
    Synaptic Transmission and Integration at a Cerebellar Synapse.” <i>ELife</i>,
    vol. 10, e63819, eLife Sciences Publications, 2021, doi:<a href="https://doi.org/10.7554/elife.63819">10.7554/elife.63819</a>.
  short: T.S. Balmer, C. Borges Merjane, L.O. Trussell, ELife 10 (2021).
date_created: 2024-04-03T07:58:11Z
date_published: 2021-02-22T00:00:00Z
date_updated: 2024-04-09T11:15:01Z
day: '22'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.7554/elife.63819
external_id:
  pmid:
  - '33616036'
file:
- access_level: open_access
  checksum: bbd4de2e54b7fbc11fba14f59e87fe3f
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-09T11:13:07Z
  date_updated: 2024-04-09T11:13:07Z
  file_id: '15307'
  file_name: 2021_eLife_Balmer.pdf
  file_size: 6997954
  relation: main_file
  success: 1
file_date_updated: 2024-04-09T11:13:07Z
has_accepted_license: '1'
intvolume: '        10'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
  issn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
status: public
title: Incomplete removal of extracellular glutamate controls synaptic transmission
  and integration at a cerebellar synapse
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2021'
...
---
_id: '15274'
abstract:
- lang: eng
  text: Copper (Cu) is a redox-active micronutrient that is both essential and toxic.
    Its cellular homeostasis is critical for supporting cuproprotein maturation while
    avoiding excessive oxidative stress. The Cu importer CcoA is the prototype of
    the widespread CalT subfamily of the MFS-type transporters. Hence, understanding
    its molecular mechanism of function is significant. Here, we show that CcoA undergoes
    a thiol:disulfide oxidoreduction cycle, which is important for its Cu import activity.
article_number: e01567
article_processing_charge: No
article_type: original
author:
- first_name: Bahia
  full_name: Khalfaoui-Hassani, Bahia
  last_name: Khalfaoui-Hassani
- first_name: Petru Iulian
  full_name: Trasnea, Petru Iulian
  id: D560034C-10C4-11EA-ABF4-A4B43DDC885E
  last_name: Trasnea
- first_name: Stefan
  full_name: Steimle, Stefan
  last_name: Steimle
- first_name: Hans-Georg
  full_name: Koch, Hans-Georg
  last_name: Koch
- first_name: Fevzi
  full_name: Daldal, Fevzi
  last_name: Daldal
citation:
  ama: Khalfaoui-Hassani B, Trasnea PI, Steimle S, Koch H-G, Daldal F. Cysteine mutants
    of the major facilitator superfamily-type transporter CcoA provide insight into
    copper import. <i>mBio</i>. 2021;12(4). doi:<a href="https://doi.org/10.1128/mbio.01567-21">10.1128/mbio.01567-21</a>
  apa: Khalfaoui-Hassani, B., Trasnea, P. I., Steimle, S., Koch, H.-G., &#38; Daldal,
    F. (2021). Cysteine mutants of the major facilitator superfamily-type transporter
    CcoA provide insight into copper import. <i>MBio</i>. American Society for Microbiology.
    <a href="https://doi.org/10.1128/mbio.01567-21">https://doi.org/10.1128/mbio.01567-21</a>
  chicago: Khalfaoui-Hassani, Bahia, Petru Iulian Trasnea, Stefan Steimle, Hans-Georg
    Koch, and Fevzi Daldal. “Cysteine Mutants of the Major Facilitator Superfamily-Type
    Transporter CcoA Provide Insight into Copper Import.” <i>MBio</i>. American Society
    for Microbiology, 2021. <a href="https://doi.org/10.1128/mbio.01567-21">https://doi.org/10.1128/mbio.01567-21</a>.
  ieee: B. Khalfaoui-Hassani, P. I. Trasnea, S. Steimle, H.-G. Koch, and F. Daldal,
    “Cysteine mutants of the major facilitator superfamily-type transporter CcoA provide
    insight into copper import,” <i>mBio</i>, vol. 12, no. 4. American Society for
    Microbiology, 2021.
  ista: Khalfaoui-Hassani B, Trasnea PI, Steimle S, Koch H-G, Daldal F. 2021. Cysteine
    mutants of the major facilitator superfamily-type transporter CcoA provide insight
    into copper import. mBio. 12(4), e01567.
  mla: Khalfaoui-Hassani, Bahia, et al. “Cysteine Mutants of the Major Facilitator
    Superfamily-Type Transporter CcoA Provide Insight into Copper Import.” <i>MBio</i>,
    vol. 12, no. 4, e01567, American Society for Microbiology, 2021, doi:<a href="https://doi.org/10.1128/mbio.01567-21">10.1128/mbio.01567-21</a>.
  short: B. Khalfaoui-Hassani, P.I. Trasnea, S. Steimle, H.-G. Koch, F. Daldal, MBio
    12 (2021).
date_created: 2024-04-03T07:59:04Z
date_published: 2021-08-31T00:00:00Z
date_updated: 2024-04-09T10:47:16Z
day: '31'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.1128/mbio.01567-21
external_id:
  pmid:
  - '34281385'
file:
- access_level: open_access
  checksum: 2f6a57637cb3162eaeeb155a5b031e76
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-09T10:45:11Z
  date_updated: 2024-04-09T10:45:11Z
  file_id: '15306'
  file_name: 2021_mBio_KhalfaouiHassani.pdf
  file_size: 3383398
  relation: main_file
  success: 1
file_date_updated: 2024-04-09T10:45:11Z
has_accepted_license: '1'
intvolume: '        12'
issue: '4'
keyword:
- Virology
- Microbiology
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: mBio
publication_identifier:
  issn:
  - 2150-7511
publication_status: published
publisher: American Society for Microbiology
quality_controlled: '1'
status: public
title: Cysteine mutants of the major facilitator superfamily-type transporter CcoA
  provide insight into copper import
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2021'
...
---
_id: '15275'
abstract:
- lang: eng
  text: In 1916, Schur introduced the Ramsey number r(3; m), which is the minimum
    integer n > 1 such that for any m-coloring of the edges of the complete graph
    Kn, there is a monochromatic copy of K3. He showed that r(3; m) ≤ O(m!), and a
    simple construction demonstrates that r(3; m) ≥ 2Ω(m). An old conjecture of Erdős
    states that r(3; m) = 2Θ(m). In this note, we prove the conjecture for m-colorings
    with bounded VC-dimension, that is, for m-colorings with the property that the
    set system induced by the neighborhoods of the vertices with respect to each color
    class has bounded VC-dimension.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jacob
  full_name: Fox, Jacob
  last_name: Fox
- first_name: János
  full_name: Pach, János
  id: E62E3130-B088-11EA-B919-BF823C25FEA4
  last_name: Pach
- first_name: Andrew
  full_name: Suk, Andrew
  last_name: Suk
citation:
  ama: Fox J, Pach J, Suk A. Bounded VC-dimension implies the Schur-Erdős conjecture.
    <i>Combinatorica</i>. 2021;41(6):803-813. doi:<a href="https://doi.org/10.1007/s00493-021-4530-9">10.1007/s00493-021-4530-9</a>
  apa: Fox, J., Pach, J., &#38; Suk, A. (2021). Bounded VC-dimension implies the Schur-Erdős
    conjecture. <i>Combinatorica</i>. Springer Nature. <a href="https://doi.org/10.1007/s00493-021-4530-9">https://doi.org/10.1007/s00493-021-4530-9</a>
  chicago: Fox, Jacob, János Pach, and Andrew Suk. “Bounded VC-Dimension Implies the
    Schur-Erdős Conjecture.” <i>Combinatorica</i>. Springer Nature, 2021. <a href="https://doi.org/10.1007/s00493-021-4530-9">https://doi.org/10.1007/s00493-021-4530-9</a>.
  ieee: J. Fox, J. Pach, and A. Suk, “Bounded VC-dimension implies the Schur-Erdős
    conjecture,” <i>Combinatorica</i>, vol. 41, no. 6. Springer Nature, pp. 803–813,
    2021.
  ista: Fox J, Pach J, Suk A. 2021. Bounded VC-dimension implies the Schur-Erdős conjecture.
    Combinatorica. 41(6), 803–813.
  mla: Fox, Jacob, et al. “Bounded VC-Dimension Implies the Schur-Erdős Conjecture.”
    <i>Combinatorica</i>, vol. 41, no. 6, Springer Nature, 2021, pp. 803–13, doi:<a
    href="https://doi.org/10.1007/s00493-021-4530-9">10.1007/s00493-021-4530-9</a>.
  short: J. Fox, J. Pach, A. Suk, Combinatorica 41 (2021) 803–813.
date_created: 2024-04-03T07:59:57Z
date_published: 2021-11-20T00:00:00Z
date_updated: 2024-04-09T10:40:08Z
day: '20'
department:
- _id: HeEd
doi: 10.1007/s00493-021-4530-9
external_id:
  arxiv:
  - '1912.02342'
intvolume: '        41'
issue: '6'
keyword:
- Computational Mathematics
- Discrete Mathematics and Combinatorics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1912.02342
month: '11'
oa: 1
oa_version: Preprint
page: 803-813
publication: Combinatorica
publication_identifier:
  eissn:
  - 1439-6912
  issn:
  - 0209-9683
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Bounded VC-dimension implies the Schur-Erdős conjecture
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 41
year: '2021'
...
---
_id: '15276'
abstract:
- lang: eng
  text: Biotrophic plant pathogens secrete effector proteins to manipulate the host
    physiology. Effectors suppress defenses and induce an environment favorable to
    disease development. Sequence-based prediction of effector function is impeded
    by their rapid evolution rate. In the maize pathogen <jats:italic>Ustilago maydis</jats:italic>,
    effector-coding genes frequently organize in clusters. Here we describe the functional
    characterization of the <jats:italic>pleiades</jats:italic>, a cluster of ten
    effector genes, by analyzing the micro- and macroscopic phenotype of the cluster
    deletion and expressing these proteins <jats:italic>in planta</jats:italic>. Deletion
    of the <jats:italic>pleiades</jats:italic> leads to strongly impaired virulence
    and accumulation of reactive oxygen species (ROS) in infected tissue. Eight of
    the Pleiades suppress the production of ROS upon perception of pathogen associated
    molecular patterns (PAMPs). Although functionally redundant, the Pleiades target
    different host components. The paralogs Taygeta1 and Merope1 suppress ROS production
    in either the cytoplasm or nucleus, respectively. Merope1 targets and promotes
    the auto-ubiquitination activity of RFI2, a conserved family of E3 ligases that
    regulates the production of PAMP-triggered ROS burst in plants.
article_number: e1009641
article_processing_charge: Yes
article_type: original
author:
- first_name: Fernando
  full_name: Navarrete, Fernando
  last_name: Navarrete
- first_name: Nenad
  full_name: Grujic, Nenad
  last_name: Grujic
- first_name: Alexandra
  full_name: Stirnberg, Alexandra
  last_name: Stirnberg
- first_name: Indira
  full_name: Saado, Indira
  last_name: Saado
- first_name: David
  full_name: Aleksza, David
  last_name: Aleksza
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
- first_name: Hazem
  full_name: Adi, Hazem
  last_name: Adi
- first_name: André
  full_name: Alcântara, André
  last_name: Alcântara
- first_name: Mamoona
  full_name: Khan, Mamoona
  last_name: Khan
- first_name: Janos
  full_name: Bindics, Janos
  last_name: Bindics
- first_name: Marco
  full_name: Trujillo, Marco
  last_name: Trujillo
- first_name: Armin
  full_name: Djamei, Armin
  last_name: Djamei
citation:
  ama: Navarrete F, Grujic N, Stirnberg A, et al. The Pleiades are a cluster of fungal
    effectors that inhibit host defenses. <i>PLOS Pathogens</i>. 2021;17(6). doi:<a
    href="https://doi.org/10.1371/journal.ppat.1009641">10.1371/journal.ppat.1009641</a>
  apa: Navarrete, F., Grujic, N., Stirnberg, A., Saado, I., Aleksza, D., Gallei, M.
    C., … Djamei, A. (2021). The Pleiades are a cluster of fungal effectors that inhibit
    host defenses. <i>PLOS Pathogens</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.ppat.1009641">https://doi.org/10.1371/journal.ppat.1009641</a>
  chicago: Navarrete, Fernando, Nenad Grujic, Alexandra Stirnberg, Indira Saado, David
    Aleksza, Michelle C Gallei, Hazem Adi, et al. “The Pleiades Are a Cluster of Fungal
    Effectors That Inhibit Host Defenses.” <i>PLOS Pathogens</i>. Public Library of
    Science, 2021. <a href="https://doi.org/10.1371/journal.ppat.1009641">https://doi.org/10.1371/journal.ppat.1009641</a>.
  ieee: F. Navarrete <i>et al.</i>, “The Pleiades are a cluster of fungal effectors
    that inhibit host defenses,” <i>PLOS Pathogens</i>, vol. 17, no. 6. Public Library
    of Science, 2021.
  ista: Navarrete F, Grujic N, Stirnberg A, Saado I, Aleksza D, Gallei MC, Adi H,
    Alcântara A, Khan M, Bindics J, Trujillo M, Djamei A. 2021. The Pleiades are a
    cluster of fungal effectors that inhibit host defenses. PLOS Pathogens. 17(6),
    e1009641.
  mla: Navarrete, Fernando, et al. “The Pleiades Are a Cluster of Fungal Effectors
    That Inhibit Host Defenses.” <i>PLOS Pathogens</i>, vol. 17, no. 6, e1009641,
    Public Library of Science, 2021, doi:<a href="https://doi.org/10.1371/journal.ppat.1009641">10.1371/journal.ppat.1009641</a>.
  short: F. Navarrete, N. Grujic, A. Stirnberg, I. Saado, D. Aleksza, M.C. Gallei,
    H. Adi, A. Alcântara, M. Khan, J. Bindics, M. Trujillo, A. Djamei, PLOS Pathogens
    17 (2021).
date_created: 2024-04-03T08:00:34Z
date_published: 2021-06-24T00:00:00Z
date_updated: 2024-04-09T10:26:12Z
day: '24'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1371/journal.ppat.1009641
external_id:
  pmid:
  - '34166468'
file:
- access_level: open_access
  checksum: ab8428291a0c14607c4ea5656c029cff
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-09T10:24:43Z
  date_updated: 2024-04-09T10:24:43Z
  file_id: '15305'
  file_name: 2021_PlosPathogens_Navarrete.pdf
  file_size: 2616563
  relation: main_file
  success: 1
file_date_updated: 2024-04-09T10:24:43Z
has_accepted_license: '1'
intvolume: '        17'
issue: '6'
keyword:
- Virology
- Genetics
- Molecular Biology
- Immunology
- Microbiology
- Parasitology
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLOS Pathogens
publication_identifier:
  issn:
  - 1553-7374
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
status: public
title: The Pleiades are a cluster of fungal effectors that inhibit host defenses
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2021'
...
---
_id: '15277'
abstract:
- lang: eng
  text: Alternative splicing generates multiple transcript and protein isoforms from
    a single gene and controls transcript intracellular localization and stability
    by coupling to mRNA export and nonsense-mediated mRNA decay (NMD). RNA interference
    (RNAi) is a potent mechanism to modulate gene expression. However, its interactions
    with alternative splicing are poorly understood. We used artificial microRNAs
    (amiRNAs, also termed shRNAmiR) to knockdown all splice variants of selected target
    genes in Arabidopsis thaliana. We found that splice variants, which vary by their
    protein-coding capacity, subcellular localization and sensitivity to NMD, are
    affected differentially by an amiRNA, although all of them contain the target
    site. Particular transcript isoforms escape amiRNA-mediated degradation due to
    their nuclear localization. The nuclear and NMD-sensitive isoforms mask RNAi action
    in alternatively spliced genes. Interestingly, Arabidopsis SPL genes, which undergo
    alternative splicing and are targets of miR156, are regulated in the same manner.
    Moreover, similar results were obtained in mammalian cells using siRNAs, indicating
    cross-kingdom conservation of these interactions among RNAi and splicing isoforms.
    Furthermore, we report that amiRNA can trigger artificial alternative splicing,
    thus expanding the RNAi functional repertoire. Our findings unveil novel interactions
    between different post-transcriptional processes in defining transcript fates
    and regulating gene expression.
article_processing_charge: No
article_type: original
author:
- first_name: Armin
  full_name: Fuchs, Armin
  last_name: Fuchs
- first_name: Stefan
  full_name: Riegler, Stefan
  last_name: Riegler
- first_name: Zahra
  full_name: Ayatollahi, Zahra
  last_name: Ayatollahi
- first_name: Nicola
  full_name: Cavallari, Nicola
  id: 457160E6-F248-11E8-B48F-1D18A9856A87
  last_name: Cavallari
- first_name: Luciana E
  full_name: Giono, Luciana E
  last_name: Giono
- first_name: Barbara A
  full_name: Nimeth, Barbara A
  last_name: Nimeth
- first_name: Krishna V
  full_name: Mutanwad, Krishna V
  last_name: Mutanwad
- first_name: Alois
  full_name: Schweighofer, Alois
  last_name: Schweighofer
- first_name: Doris
  full_name: Lucyshyn, Doris
  last_name: Lucyshyn
- first_name: Andrea
  full_name: Barta, Andrea
  last_name: Barta
- first_name: Ezequiel
  full_name: Petrillo, Ezequiel
  last_name: Petrillo
- first_name: Maria
  full_name: Kalyna, Maria
  last_name: Kalyna
citation:
  ama: 'Fuchs A, Riegler S, Ayatollahi Z, et al. Targeting alternative splicing by
    RNAi: From the differential impact on splice variants to triggering artificial
    pre-mRNA splicing. <i>Nucleic Acids Research</i>. 2021;49(2):1133-1151. doi:<a
    href="https://doi.org/10.1093/nar/gkaa1260">10.1093/nar/gkaa1260</a>'
  apa: 'Fuchs, A., Riegler, S., Ayatollahi, Z., Cavallari, N., Giono, L. E., Nimeth,
    B. A., … Kalyna, M. (2021). Targeting alternative splicing by RNAi: From the differential
    impact on splice variants to triggering artificial pre-mRNA splicing. <i>Nucleic
    Acids Research</i>. Oxford University Press. <a href="https://doi.org/10.1093/nar/gkaa1260">https://doi.org/10.1093/nar/gkaa1260</a>'
  chicago: 'Fuchs, Armin, Stefan Riegler, Zahra Ayatollahi, Nicola Cavallari, Luciana
    E Giono, Barbara A Nimeth, Krishna V Mutanwad, et al. “Targeting Alternative Splicing
    by RNAi: From the Differential Impact on Splice Variants to Triggering Artificial
    Pre-MRNA Splicing.” <i>Nucleic Acids Research</i>. Oxford University Press, 2021.
    <a href="https://doi.org/10.1093/nar/gkaa1260">https://doi.org/10.1093/nar/gkaa1260</a>.'
  ieee: 'A. Fuchs <i>et al.</i>, “Targeting alternative splicing by RNAi: From the
    differential impact on splice variants to triggering artificial pre-mRNA splicing,”
    <i>Nucleic Acids Research</i>, vol. 49, no. 2. Oxford University Press, pp. 1133–1151,
    2021.'
  ista: 'Fuchs A, Riegler S, Ayatollahi Z, Cavallari N, Giono LE, Nimeth BA, Mutanwad
    KV, Schweighofer A, Lucyshyn D, Barta A, Petrillo E, Kalyna M. 2021. Targeting
    alternative splicing by RNAi: From the differential impact on splice variants
    to triggering artificial pre-mRNA splicing. Nucleic Acids Research. 49(2), 1133–1151.'
  mla: 'Fuchs, Armin, et al. “Targeting Alternative Splicing by RNAi: From the Differential
    Impact on Splice Variants to Triggering Artificial Pre-MRNA Splicing.” <i>Nucleic
    Acids Research</i>, vol. 49, no. 2, Oxford University Press, 2021, pp. 1133–51,
    doi:<a href="https://doi.org/10.1093/nar/gkaa1260">10.1093/nar/gkaa1260</a>.'
  short: A. Fuchs, S. Riegler, Z. Ayatollahi, N. Cavallari, L.E. Giono, B.A. Nimeth,
    K.V. Mutanwad, A. Schweighofer, D. Lucyshyn, A. Barta, E. Petrillo, M. Kalyna,
    Nucleic Acids Research 49 (2021) 1133–1151.
date_created: 2024-04-03T08:02:09Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2024-04-09T10:16:40Z
day: '25'
ddc:
- '570'
department:
- _id: EvBe
doi: 10.1093/nar/gkaa1260
external_id:
  pmid:
  - '33406240'
file:
- access_level: open_access
  checksum: d3c90660759a5d34ad43ba1def130462
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-09T10:14:39Z
  date_updated: 2024-04-09T10:14:39Z
  file_id: '15304'
  file_name: 2021_NucleicAcidsRes_Fuchs.pdf
  file_size: 6539791
  relation: main_file
  success: 1
file_date_updated: 2024-04-09T10:14:39Z
has_accepted_license: '1'
intvolume: '        49'
issue: '2'
keyword:
- Genetics
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 1133-1151
pmid: 1
publication: Nucleic Acids Research
publication_identifier:
  eissn:
  - 1362-4962
  issn:
  - 0305-1048
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
status: public
title: 'Targeting alternative splicing by RNAi: From the differential impact on splice
  variants to triggering artificial pre-mRNA splicing'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 49
year: '2021'
...
---
_id: '15278'
abstract:
- lang: eng
  text: ‘Dysbiosis’ of the adult gut microbiota, in response to challenges such as
    infection, altered diet, stress, and antibiotics treatment has been recently linked
    to pathological alteration of brain function and behavior. Moreover, gut microbiota
    composition constantly controls microglia maturation, as revealed by morphological
    observations and gene expression analysis. However, it is unclear whether microglia
    functional properties and crosstalk with neurons, known to shape and modulate
    synaptic development and function, are influenced by the gut microbiota. Here,
    we investigated how antibiotic-mediated alteration of the gut microbiota influences
    microglial and neuronal functions in adult mice hippocampus. Hippocampal microglia
    from adult mice treated with oral antibiotics exhibited increased microglia density,
    altered basal patrolling activity, and impaired process rearrangement in response
    to damage. Patch clamp recordings at CA3-CA1 synapses revealed that antibiotics
    treatment alters neuronal functions, reducing spontaneous postsynaptic glutamatergic
    currents and decreasing synaptic connectivity, without reducing dendritic spines
    density. Antibiotics treatment was unable to modulate synaptic function in CX3CR1-deficient
    mice, pointing to an involvement of microglia–neuron crosstalk through the CX3CL1/CX3CR1
    axis in the effect of dysbiosis on neuronal functions. Together, our findings
    show that antibiotic alteration of gut microbiota impairs synaptic efficacy, suggesting
    that CX3CL1/CX3CR1 signaling supporting microglia is a major player in in the
    gut–brain axis, and in particular in the gut microbiota-to-neuron communication
    pathway.
article_number: '2648'
article_processing_charge: Yes
article_type: original
author:
- first_name: Federica
  full_name: Cordella, Federica
  last_name: Cordella
- first_name: Caterina
  full_name: Sanchini, Caterina
  last_name: Sanchini
- first_name: Maria
  full_name: Rosito, Maria
  last_name: Rosito
- first_name: Laura
  full_name: Ferrucci, Laura
  last_name: Ferrucci
- first_name: Natalia
  full_name: Pediconi, Natalia
  last_name: Pediconi
- first_name: Barbara
  full_name: Cortese, Barbara
  last_name: Cortese
- first_name: Francesca
  full_name: Guerrieri, Francesca
  last_name: Guerrieri
- first_name: Giuseppe Rubens
  full_name: Pascucci, Giuseppe Rubens
  last_name: Pascucci
- first_name: Fabrizio
  full_name: Antonangeli, Fabrizio
  last_name: Antonangeli
- first_name: Giovanna
  full_name: Peruzzi, Giovanna
  last_name: Peruzzi
- first_name: Maria
  full_name: Giubettini, Maria
  last_name: Giubettini
- first_name: Bernadette
  full_name: Basilico, Bernadette
  id: 36035796-5ACA-11E9-A75E-7AF2E5697425
  last_name: Basilico
  orcid: 0000-0003-1843-3173
- first_name: Francesca
  full_name: Pagani, Francesca
  last_name: Pagani
- first_name: Alfonso
  full_name: Grimaldi, Alfonso
  last_name: Grimaldi
- first_name: Giuseppina
  full_name: D’Alessandro, Giuseppina
  last_name: D’Alessandro
- first_name: Cristina
  full_name: Limatola, Cristina
  last_name: Limatola
- first_name: Davide
  full_name: Ragozzino, Davide
  last_name: Ragozzino
- first_name: Silvia
  full_name: Di Angelantonio, Silvia
  last_name: Di Angelantonio
citation:
  ama: Cordella F, Sanchini C, Rosito M, et al. Antibiotics treatment modulates microglia–synapses
    interaction. <i>Cells</i>. 2021;10(10). doi:<a href="https://doi.org/10.3390/cells10102648">10.3390/cells10102648</a>
  apa: Cordella, F., Sanchini, C., Rosito, M., Ferrucci, L., Pediconi, N., Cortese,
    B., … Di Angelantonio, S. (2021). Antibiotics treatment modulates microglia–synapses
    interaction. <i>Cells</i>. MDPI. <a href="https://doi.org/10.3390/cells10102648">https://doi.org/10.3390/cells10102648</a>
  chicago: Cordella, Federica, Caterina Sanchini, Maria Rosito, Laura Ferrucci, Natalia
    Pediconi, Barbara Cortese, Francesca Guerrieri, et al. “Antibiotics Treatment
    Modulates Microglia–Synapses Interaction.” <i>Cells</i>. MDPI, 2021. <a href="https://doi.org/10.3390/cells10102648">https://doi.org/10.3390/cells10102648</a>.
  ieee: F. Cordella <i>et al.</i>, “Antibiotics treatment modulates microglia–synapses
    interaction,” <i>Cells</i>, vol. 10, no. 10. MDPI, 2021.
  ista: Cordella F, Sanchini C, Rosito M, Ferrucci L, Pediconi N, Cortese B, Guerrieri
    F, Pascucci GR, Antonangeli F, Peruzzi G, Giubettini M, Basilico B, Pagani F,
    Grimaldi A, D’Alessandro G, Limatola C, Ragozzino D, Di Angelantonio S. 2021.
    Antibiotics treatment modulates microglia–synapses interaction. Cells. 10(10),
    2648.
  mla: Cordella, Federica, et al. “Antibiotics Treatment Modulates Microglia–Synapses
    Interaction.” <i>Cells</i>, vol. 10, no. 10, 2648, MDPI, 2021, doi:<a href="https://doi.org/10.3390/cells10102648">10.3390/cells10102648</a>.
  short: F. Cordella, C. Sanchini, M. Rosito, L. Ferrucci, N. Pediconi, B. Cortese,
    F. Guerrieri, G.R. Pascucci, F. Antonangeli, G. Peruzzi, M. Giubettini, B. Basilico,
    F. Pagani, A. Grimaldi, G. D’Alessandro, C. Limatola, D. Ragozzino, S. Di Angelantonio,
    Cells 10 (2021).
date_created: 2024-04-03T08:02:52Z
date_published: 2021-10-04T00:00:00Z
date_updated: 2024-04-09T08:53:23Z
day: '04'
ddc:
- '610'
department:
- _id: GaNo
doi: 10.3390/cells10102648
external_id:
  pmid:
  - '34685628'
file:
- access_level: open_access
  checksum: 1a3b251ce82e2b9474b852d2abe5bb03
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-09T08:51:22Z
  date_updated: 2024-04-09T08:51:22Z
  file_id: '15303'
  file_name: 2021_Cells_Cordella.pdf
  file_size: 2196672
  relation: main_file
  success: 1
file_date_updated: 2024-04-09T08:51:22Z
has_accepted_license: '1'
intvolume: '        10'
issue: '10'
keyword:
- General Medicine
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cells
publication_identifier:
  issn:
  - 2073-4409
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Antibiotics treatment modulates microglia–synapses interaction
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2021'
...
---
_id: '15279'
abstract:
- lang: eng
  text: We formulate and prove an analog of Poonen’s finite-field Bertini theorem
    with Taylor conditions that holds in the Grothendieck ring of varieties. This
    gives a broad generalization of the work of Vakil and Wood, who treated the case
    of smooth hypersurface sections, and is made possible by the use of motivic Euler
    products to write down candidate motivic probabilities. As applications, we give
    motivic analogs of many results in arithmetic statistics that have been proven
    using Poonen’s sieve, including work of Bucur and Kedlaya on complete intersections
    and Erman and Wood on semiample Bertini theorems.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Margaret
  full_name: Bilu, Margaret
  id: 98C47862-10D5-11EA-BEDD-0F6F3DDC885E
  last_name: Bilu
- first_name: Sean
  full_name: Howe, Sean
  last_name: Howe
citation:
  ama: Bilu M, Howe S. Motivic Euler products in motivic statistics. <i>Algebra &#38;
    Number Theory</i>. 2021;15(9):2195-2259. doi:<a href="https://doi.org/10.2140/ant.2021.15.2195">10.2140/ant.2021.15.2195</a>
  apa: Bilu, M., &#38; Howe, S. (2021). Motivic Euler products in motivic statistics.
    <i>Algebra &#38; Number Theory</i>. Mathematical Sciences Publishers. <a href="https://doi.org/10.2140/ant.2021.15.2195">https://doi.org/10.2140/ant.2021.15.2195</a>
  chicago: Bilu, Margaret, and Sean Howe. “Motivic Euler Products in Motivic Statistics.”
    <i>Algebra &#38; Number Theory</i>. Mathematical Sciences Publishers, 2021. <a
    href="https://doi.org/10.2140/ant.2021.15.2195">https://doi.org/10.2140/ant.2021.15.2195</a>.
  ieee: M. Bilu and S. Howe, “Motivic Euler products in motivic statistics,” <i>Algebra
    &#38; Number Theory</i>, vol. 15, no. 9. Mathematical Sciences Publishers, pp.
    2195–2259, 2021.
  ista: Bilu M, Howe S. 2021. Motivic Euler products in motivic statistics. Algebra
    &#38; Number Theory. 15(9), 2195–2259.
  mla: Bilu, Margaret, and Sean Howe. “Motivic Euler Products in Motivic Statistics.”
    <i>Algebra &#38; Number Theory</i>, vol. 15, no. 9, Mathematical Sciences Publishers,
    2021, pp. 2195–259, doi:<a href="https://doi.org/10.2140/ant.2021.15.2195">10.2140/ant.2021.15.2195</a>.
  short: M. Bilu, S. Howe, Algebra &#38; Number Theory 15 (2021) 2195–2259.
corr_author: '1'
date_created: 2024-04-03T08:12:59Z
date_published: 2021-12-23T00:00:00Z
date_updated: 2024-10-21T06:02:15Z
day: '23'
department:
- _id: TiBr
doi: 10.2140/ant.2021.15.2195
external_id:
  arxiv:
  - '1910.05207'
intvolume: '        15'
issue: '9'
keyword:
- Algebra and Number Theory
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1910.05207
month: '12'
oa: 1
oa_version: Preprint
page: 2195-2259
publication: Algebra & Number Theory
publication_identifier:
  eissn:
  - 1944-7833
  issn:
  - 1937-0652
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Motivic Euler products in motivic statistics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2021'
...
---
_id: '15280'
article_number: '050'
article_processing_charge: No
author:
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Jessica
  full_name: Cimada da Silva, Jessica
  last_name: Cimada da Silva
- first_name: Tyler
  full_name: Dunbar, Tyler
  last_name: Dunbar
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Tobias
  full_name: Hanrath, Tobias
  last_name: Hanrath
citation:
  ama: 'Balazs D, Cimada da Silva J, Dunbar T, Ibáñez M, Hanrath T. Controlled reactive
    assembly of colloidal nanocrystal superlattices: Mechanism and kinetics. In: <i>Proceedings
    of the Internet NanoGe Conference on Nanocrystals</i>. Fundació Scito; 2021. doi:<a
    href="https://doi.org/10.29363/nanoge.incnc.2021.050">10.29363/nanoge.incnc.2021.050</a>'
  apa: 'Balazs, D., Cimada da Silva, J., Dunbar, T., Ibáñez, M., &#38; Hanrath, T.
    (2021). Controlled reactive assembly of colloidal nanocrystal superlattices: Mechanism
    and kinetics. In <i>Proceedings of the Internet NanoGe Conference on Nanocrystals</i>.
    Virtual: Fundació Scito. <a href="https://doi.org/10.29363/nanoge.incnc.2021.050">https://doi.org/10.29363/nanoge.incnc.2021.050</a>'
  chicago: 'Balazs, Daniel, Jessica Cimada da Silva, Tyler Dunbar, Maria Ibáñez, and
    Tobias Hanrath. “Controlled Reactive Assembly of Colloidal Nanocrystal Superlattices:
    Mechanism and Kinetics.” In <i>Proceedings of the Internet NanoGe Conference on
    Nanocrystals</i>. Fundació Scito, 2021. <a href="https://doi.org/10.29363/nanoge.incnc.2021.050">https://doi.org/10.29363/nanoge.incnc.2021.050</a>.'
  ieee: 'D. Balazs, J. Cimada da Silva, T. Dunbar, M. Ibáñez, and T. Hanrath, “Controlled
    reactive assembly of colloidal nanocrystal superlattices: Mechanism and kinetics,”
    in <i>Proceedings of the Internet NanoGe Conference on Nanocrystals</i>, Virtual,
    2021.'
  ista: 'Balazs D, Cimada da Silva J, Dunbar T, Ibáñez M, Hanrath T. 2021. Controlled
    reactive assembly of colloidal nanocrystal superlattices: Mechanism and kinetics.
    Proceedings of the Internet NanoGe Conference on Nanocrystals. iNCNC: Internet
    nanoGe Conference on Nanocrystals, 050.'
  mla: 'Balazs, Daniel, et al. “Controlled Reactive Assembly of Colloidal Nanocrystal
    Superlattices: Mechanism and Kinetics.” <i>Proceedings of the Internet NanoGe
    Conference on Nanocrystals</i>, 050, Fundació Scito, 2021, doi:<a href="https://doi.org/10.29363/nanoge.incnc.2021.050">10.29363/nanoge.incnc.2021.050</a>.'
  short: D. Balazs, J. Cimada da Silva, T. Dunbar, M. Ibáñez, T. Hanrath, in:, Proceedings
    of the Internet NanoGe Conference on Nanocrystals, Fundació Scito, 2021.
conference:
  end_date: 2021-07-02
  location: Virtual
  name: 'iNCNC: Internet nanoGe Conference on Nanocrystals'
  start_date: 2021-06-28
corr_author: '1'
date_created: 2024-04-03T08:28:26Z
date_published: 2021-06-08T00:00:00Z
date_updated: 2024-10-09T21:08:49Z
day: '08'
department:
- _id: MaIb
- _id: LifeSc
doi: 10.29363/nanoge.incnc.2021.050
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.29363/nanoge.incnc.2021.050
month: '06'
oa: 1
oa_version: Published Version
publication: Proceedings of the Internet NanoGe Conference on Nanocrystals
publication_status: published
publisher: Fundació Scito
quality_controlled: '1'
status: public
title: 'Controlled reactive assembly of colloidal nanocrystal superlattices: Mechanism
  and kinetics'
type: conference_abstract
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '15283'
article_processing_charge: No
article_type: original
author:
- first_name: William
  full_name: Nicolas, William
  last_name: Nicolas
- first_name: Florian
  full_name: Fäßler, Florian
  id: 404F5528-F248-11E8-B48F-1D18A9856A87
  last_name: Fäßler
  orcid: 0000-0001-7149-769X
- first_name: Elliot
  full_name: Meyerowitz, Elliot
  last_name: Meyerowitz
- first_name: Grant
  full_name: Jensen, Grant
  last_name: Jensen
citation:
  ama: Nicolas W, Fäßler F, Meyerowitz E, Jensen G. Peaking into the plant cell wall
    using cryo-FIB milling and electron cryo-tomography. <i>Microscopy and Microanalysis</i>.
    2021;27(S1):3024-3026. doi:<a href="https://doi.org/10.1017/s1431927621010503">10.1017/s1431927621010503</a>
  apa: Nicolas, W., Fäßler, F., Meyerowitz, E., &#38; Jensen, G. (2021). Peaking into
    the plant cell wall using cryo-FIB milling and electron cryo-tomography. <i>Microscopy
    and Microanalysis</i>. Oxford University Press. <a href="https://doi.org/10.1017/s1431927621010503">https://doi.org/10.1017/s1431927621010503</a>
  chicago: Nicolas, William, Florian Fäßler, Elliot Meyerowitz, and Grant Jensen.
    “Peaking into the Plant Cell Wall Using Cryo-FIB Milling and Electron Cryo-Tomography.”
    <i>Microscopy and Microanalysis</i>. Oxford University Press, 2021. <a href="https://doi.org/10.1017/s1431927621010503">https://doi.org/10.1017/s1431927621010503</a>.
  ieee: W. Nicolas, F. Fäßler, E. Meyerowitz, and G. Jensen, “Peaking into the plant
    cell wall using cryo-FIB milling and electron cryo-tomography,” <i>Microscopy
    and Microanalysis</i>, vol. 27, no. S1. Oxford University Press, pp. 3024–3026,
    2021.
  ista: Nicolas W, Fäßler F, Meyerowitz E, Jensen G. 2021. Peaking into the plant
    cell wall using cryo-FIB milling and electron cryo-tomography. Microscopy and
    Microanalysis. 27(S1), 3024–3026.
  mla: Nicolas, William, et al. “Peaking into the Plant Cell Wall Using Cryo-FIB Milling
    and Electron Cryo-Tomography.” <i>Microscopy and Microanalysis</i>, vol. 27, no.
    S1, Oxford University Press, 2021, pp. 3024–26, doi:<a href="https://doi.org/10.1017/s1431927621010503">10.1017/s1431927621010503</a>.
  short: W. Nicolas, F. Fäßler, E. Meyerowitz, G. Jensen, Microscopy and Microanalysis
    27 (2021) 3024–3026.
date_created: 2024-04-03T08:57:23Z
date_published: 2021-08-01T00:00:00Z
date_updated: 2024-04-09T07:55:56Z
day: '01'
department:
- _id: FlSc
doi: 10.1017/s1431927621010503
intvolume: '        27'
issue: S1
keyword:
- Instrumentation
language:
- iso: eng
month: '08'
oa_version: None
page: 3024-3026
publication: Microscopy and Microanalysis
publication_identifier:
  eissn:
  - 1435-8115
  issn:
  - 1431-9276
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
status: public
title: Peaking into the plant cell wall using cryo-FIB milling and electron cryo-tomography
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2021'
...
---
_id: '15284'
abstract:
- lang: eng
  text: "RevTerm is a static analysis tool for proving non-termination of integer
    C programs (possibly with non-determinism). RevTerm is an implementation of our
    method for non-termination proving presented in the paper “Proving Non-termination
    by Program Reversal”.\r\n\r\n"
article_processing_charge: No
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Ehsan Kafshdar
  full_name: Goharshady, Ehsan Kafshdar
  last_name: Goharshady
- first_name: Petr
  full_name: Novotný, Petr
  id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
  last_name: Novotný
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
citation:
  ama: Chatterjee K, Goharshady EK, Novotný P, Zikelic D. RevTerm. 2021. doi:<a href="https://doi.org/10.1145/3410304">10.1145/3410304</a>
  apa: Chatterjee, K., Goharshady, E. K., Novotný, P., &#38; Zikelic, D. (2021). RevTerm.
    Association for Computing Machinery. <a href="https://doi.org/10.1145/3410304">https://doi.org/10.1145/3410304</a>
  chicago: Chatterjee, Krishnendu, Ehsan Kafshdar Goharshady, Petr Novotný, and Dorde
    Zikelic. “RevTerm.” Association for Computing Machinery, 2021. <a href="https://doi.org/10.1145/3410304">https://doi.org/10.1145/3410304</a>.
  ieee: K. Chatterjee, E. K. Goharshady, P. Novotný, and D. Zikelic, “RevTerm.” Association
    for Computing Machinery, 2021.
  ista: Chatterjee K, Goharshady EK, Novotný P, Zikelic D. 2021. RevTerm, Association
    for Computing Machinery, <a href="https://doi.org/10.1145/3410304">10.1145/3410304</a>.
  mla: Chatterjee, Krishnendu, et al. <i>RevTerm</i>. Association for Computing Machinery,
    2021, doi:<a href="https://doi.org/10.1145/3410304">10.1145/3410304</a>.
  short: K. Chatterjee, E.K. Goharshady, P. Novotný, D. Zikelic, (2021).
corr_author: '1'
date_created: 2024-04-03T09:00:42Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2025-04-15T06:25:30Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1145/3410304
has_accepted_license: '1'
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1145/3410304
month: '06'
oa: 1
oa_version: Published Version
publisher: Association for Computing Machinery
related_material:
  record:
  - id: '9644'
    relation: used_in_publication
    status: public
status: public
title: RevTerm
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '15285'
abstract:
- lang: eng
  text: Ever since the first publication of the standard communication protocol for
    computer-assisted electrocardiography (SCP-ECG), prENV 1064, in 1993, by the European
    Committee for Standardization (CEN), SCP-ECG has become a leading example in health
    informatics, enabling open, secure, and well-documented digital data exchange
    at a low cost, for quick and efficient cardiovascular disease detection and management.
    Based on the experiences gained, since the 1970s, in computerized electrocardiology,
    and on the results achieved by the pioneering, international cooperative research
    on common standards for quantitative electrocardiography (CSE), SCP-ECG was designed,
    from the beginning, to empower personalized medicine, thanks to serial ECG analysis.
    The fundamental concept behind SCP-ECG is to convey the necessary information
    for ECG re-analysis, serial comparison, and interpretation, and to structure the
    ECG data and metadata in sections that are mostly optional in order to fit all
    use cases. SCP-ECG is open to the storage of the ECG signal and ECG measurement
    data, whatever the ECG recording modality or computation method, and can store
    the over-reading trails and ECG annotations, as well as any computerized or medical
    interpretation reports. Only the encoding syntax and the semantics of the ECG
    descriptors and of the diagnosis codes are standardized. We present all of the
    landmarks in the development and publication of SCP-ECG, from the early 1990s
    to the 2009 International Organization for Standardization (ISO) SCP-ECG standards,
    including the latest version published by CEN in 2020, which now encompasses rest
    and stress ECGs, Holter recordings, and protocol-based trials.
acknowledgement: This research received no external funding. The authors thank the
  large number of researchers, engineers, cardiologists, and clinicians from academia,
  industry, and normalization organizations who contributed to the development and
  testing of the SCP-ECG standards.
article_processing_charge: Yes
article_type: review
author:
- first_name: Paul
  full_name: Rubel, Paul
  last_name: Rubel
- first_name: Jocelyne
  full_name: Fayn, Jocelyne
  last_name: Fayn
- first_name: Peter W.
  full_name: Macfarlane, Peter W.
  last_name: Macfarlane
- first_name: Danilo
  full_name: Pani, Danilo
  last_name: Pani
- first_name: Alois
  full_name: Schlögl, Alois
  id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
  last_name: Schlögl
  orcid: 0000-0002-5621-8100
- first_name: Alpo
  full_name: Värri, Alpo
  last_name: Värri
citation:
  ama: 'Rubel P, Fayn J, Macfarlane PW, Pani D, Schlögl A, Värri A. The history and
    challenges of SCP-ECG: The standard communication protocol for computer-assisted
    electrocardiography. <i>Hearts</i>. 2021;2(3):384-409. doi:<a href="https://doi.org/10.3390/hearts2030031">10.3390/hearts2030031</a>'
  apa: 'Rubel, P., Fayn, J., Macfarlane, P. W., Pani, D., Schlögl, A., &#38; Värri,
    A. (2021). The history and challenges of SCP-ECG: The standard communication protocol
    for computer-assisted electrocardiography. <i>Hearts</i>. MDPI. <a href="https://doi.org/10.3390/hearts2030031">https://doi.org/10.3390/hearts2030031</a>'
  chicago: 'Rubel, Paul, Jocelyne Fayn, Peter W. Macfarlane, Danilo Pani, Alois Schlögl,
    and Alpo Värri. “The History and Challenges of SCP-ECG: The Standard Communication
    Protocol for Computer-Assisted Electrocardiography.” <i>Hearts</i>. MDPI, 2021.
    <a href="https://doi.org/10.3390/hearts2030031">https://doi.org/10.3390/hearts2030031</a>.'
  ieee: 'P. Rubel, J. Fayn, P. W. Macfarlane, D. Pani, A. Schlögl, and A. Värri, “The
    history and challenges of SCP-ECG: The standard communication protocol for computer-assisted
    electrocardiography,” <i>Hearts</i>, vol. 2, no. 3. MDPI, pp. 384–409, 2021.'
  ista: 'Rubel P, Fayn J, Macfarlane PW, Pani D, Schlögl A, Värri A. 2021. The history
    and challenges of SCP-ECG: The standard communication protocol for computer-assisted
    electrocardiography. Hearts. 2(3), 384–409.'
  mla: 'Rubel, Paul, et al. “The History and Challenges of SCP-ECG: The Standard Communication
    Protocol for Computer-Assisted Electrocardiography.” <i>Hearts</i>, vol. 2, no.
    3, MDPI, 2021, pp. 384–409, doi:<a href="https://doi.org/10.3390/hearts2030031">10.3390/hearts2030031</a>.'
  short: P. Rubel, J. Fayn, P.W. Macfarlane, D. Pani, A. Schlögl, A. Värri, Hearts
    2 (2021) 384–409.
date_created: 2024-04-03T09:03:31Z
date_published: 2021-08-24T00:00:00Z
date_updated: 2024-04-09T06:51:50Z
day: '24'
ddc:
- '610'
department:
- _id: ScienComp
doi: 10.3390/hearts2030031
file:
- access_level: open_access
  checksum: f67142b1e1e8ca5cd7a6a6798f46375e
  content_type: application/pdf
  creator: dernst
  date_created: 2024-04-09T06:49:47Z
  date_updated: 2024-04-09T06:49:47Z
  file_id: '15302'
  file_name: 2021_Hearts_Rubel.pdf
  file_size: 3539897
  relation: main_file
  success: 1
file_date_updated: 2024-04-09T06:49:47Z
has_accepted_license: '1'
intvolume: '         2'
issue: '3'
keyword:
- General Medicine
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 384-409
publication: Hearts
publication_identifier:
  issn:
  - 2673-3846
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: 'The history and challenges of SCP-ECG: The standard communication protocol
  for computer-assisted electrocardiography'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2021'
...
---
_id: '10552'
abstract:
- lang: eng
  text: We study a class of convex-concave saddle-point problems of the form minxmaxy⟨Kx,y⟩+fP(x)−h∗(y)
    where K is a linear operator, fP is the sum of a convex function f with a Lipschitz-continuous
    gradient and the indicator function of a bounded convex polytope P, and h∗ is
    a convex (possibly nonsmooth) function. Such problem arises, for example, as a
    Lagrangian relaxation of various discrete optimization problems. Our main assumptions
    are the existence of an efficient linear minimization oracle (lmo) for fP and
    an efficient proximal map for h∗ which motivate the solution via a blend of proximal
    primal-dual algorithms and Frank-Wolfe algorithms. In case h∗ is the indicator
    function of a linear constraint and function f is quadratic, we show a O(1/n2)
    convergence rate on the dual objective, requiring O(nlogn) calls of lmo. If the
    problem comes from the constrained optimization problem minx∈Rd{fP(x)|Ax−b=0}
    then we additionally get bound O(1/n2) both on the primal gap and on the infeasibility
    gap. In the most general case, we show a O(1/n) convergence rate of the primal-dual
    gap again requiring O(nlogn) calls of lmo. To the best of our knowledge, this
    improves on the known convergence rates for the considered class of saddle-point
    problems. We show applications to labeling problems frequently appearing in machine
    learning and computer vision.
acknowledgement: Vladimir Kolmogorov was supported by the European Research Council
  under the European Unions Seventh Framework Programme (FP7/2007-2013)/ERC grant
  agreement no 616160. Thomas Pock acknowledges support by an ERC grant HOMOVIS, no
  640156.
article_processing_charge: No
arxiv: 1
author:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Thomas
  full_name: Pock, Thomas
  last_name: Pock
citation:
  ama: 'Kolmogorov V, Pock T. One-sided Frank-Wolfe algorithms for saddle problems.
    In: <i>38th International Conference on Machine Learning</i>. ; 2021.'
  apa: Kolmogorov, V., &#38; Pock, T. (2021). One-sided Frank-Wolfe algorithms for
    saddle problems. In <i>38th International Conference on Machine Learning</i>.
    Virtual.
  chicago: Kolmogorov, Vladimir, and Thomas Pock. “One-Sided Frank-Wolfe Algorithms
    for Saddle Problems.” In <i>38th International Conference on Machine Learning</i>,
    2021.
  ieee: V. Kolmogorov and T. Pock, “One-sided Frank-Wolfe algorithms for saddle problems,”
    in <i>38th International Conference on Machine Learning</i>, Virtual, 2021.
  ista: 'Kolmogorov V, Pock T. 2021. One-sided Frank-Wolfe algorithms for saddle problems.
    38th International Conference on Machine Learning. ICML: International Conference
    on Machine Learning.'
  mla: Kolmogorov, Vladimir, and Thomas Pock. “One-Sided Frank-Wolfe Algorithms for
    Saddle Problems.” <i>38th International Conference on Machine Learning</i>, 2021.
  short: V. Kolmogorov, T. Pock, in:, 38th International Conference on Machine Learning,
    2021.
conference:
  end_date: 2021-07-24
  location: Virtual
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2021-07-18
corr_author: '1'
date_created: 2021-12-16T12:41:20Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2025-07-16T08:04:23Z
day: '01'
department:
- _id: VlKo
ec_funded: 1
external_id:
  arxiv:
  - '2101.12617'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2101.12617
month: '07'
oa: 1
oa_version: Preprint
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '616160'
  name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: 38th International Conference on Machine Learning
publication_status: published
quality_controlled: '1'
scopus_import: '1'
status: public
title: One-sided Frank-Wolfe algorithms for saddle problems
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10553'
abstract:
- lang: eng
  text: The popularity of permissioned blockchain systems demands BFT SMR protocols
    that are efficient under good network conditions (synchrony) and robust under
    bad network conditions (asynchrony). The state-of-the-art partially synchronous
    BFT SMR protocols provide optimal linear communication cost per decision under
    synchrony and good leaders, but lose liveness under asynchrony. On the other hand,
    the state-of-the-art asynchronous BFT SMR protocols are live even under asynchrony,
    but always pay quadratic cost even under synchrony. In this paper, we propose
    a BFT SMR protocol that achieves the best of both worlds -- optimal linear cost
    per decision under good networks and leaders, optimal quadratic cost per decision
    under bad networks, and remains always live.
article_processing_charge: No
arxiv: 1
author:
- first_name: Rati
  full_name: Gelashvili, Rati
  last_name: Gelashvili
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
- first_name: Alexander
  full_name: Spiegelman, Alexander
  last_name: Spiegelman
- first_name: Zhuolun
  full_name: Xiang, Zhuolun
  last_name: Xiang
citation:
  ama: 'Gelashvili R, Kokoris Kogias E, Spiegelman A, Xiang Z. Brief announcement:
    Be prepared when network goes bad: An asynchronous view-change protocol. In: <i>Proceedings
    of the 2021 ACM Symposium on Principles of Distributed Computing</i>. Association
    for Computing Machinery; 2021:187-190. doi:<a href="https://doi.org/10.1145/3465084.3467941">10.1145/3465084.3467941</a>'
  apa: 'Gelashvili, R., Kokoris Kogias, E., Spiegelman, A., &#38; Xiang, Z. (2021).
    Brief announcement: Be prepared when network goes bad: An asynchronous view-change
    protocol. In <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing</i> (pp. 187–190). Virtual, Italy: Association for Computing Machinery.
    <a href="https://doi.org/10.1145/3465084.3467941">https://doi.org/10.1145/3465084.3467941</a>'
  chicago: 'Gelashvili, Rati, Eleftherios Kokoris Kogias, Alexander Spiegelman, and
    Zhuolun Xiang. “Brief Announcement: Be Prepared When Network Goes Bad: An Asynchronous
    View-Change Protocol.” In <i>Proceedings of the 2021 ACM Symposium on Principles
    of Distributed Computing</i>, 187–90. Association for Computing Machinery, 2021.
    <a href="https://doi.org/10.1145/3465084.3467941">https://doi.org/10.1145/3465084.3467941</a>.'
  ieee: 'R. Gelashvili, E. Kokoris Kogias, A. Spiegelman, and Z. Xiang, “Brief announcement:
    Be prepared when network goes bad: An asynchronous view-change protocol,” in <i>Proceedings
    of the 2021 ACM Symposium on Principles of Distributed Computing</i>, Virtual,
    Italy, 2021, pp. 187–190.'
  ista: 'Gelashvili R, Kokoris Kogias E, Spiegelman A, Xiang Z. 2021. Brief announcement:
    Be prepared when network goes bad: An asynchronous view-change protocol. Proceedings
    of the 2021 ACM Symposium on Principles of Distributed Computing. PODC: Principles
    of Distributed Computing, 187–190.'
  mla: 'Gelashvili, Rati, et al. “Brief Announcement: Be Prepared When Network Goes
    Bad: An Asynchronous View-Change Protocol.” <i>Proceedings of the 2021 ACM Symposium
    on Principles of Distributed Computing</i>, Association for Computing Machinery,
    2021, pp. 187–90, doi:<a href="https://doi.org/10.1145/3465084.3467941">10.1145/3465084.3467941</a>.'
  short: R. Gelashvili, E. Kokoris Kogias, A. Spiegelman, Z. Xiang, in:, Proceedings
    of the 2021 ACM Symposium on Principles of Distributed Computing, Association
    for Computing Machinery, 2021, pp. 187–190.
conference:
  end_date: 2021-07-30
  location: Virtual, Italy
  name: 'PODC: Principles of Distributed Computing'
  start_date: 2021-07-26
date_created: 2021-12-16T13:20:19Z
date_published: 2021-07-21T00:00:00Z
date_updated: 2023-09-04T11:42:10Z
day: '21'
department:
- _id: ElKo
doi: 10.1145/3465084.3467941
external_id:
  arxiv:
  - '2103.03181'
  isi:
  - '000744439800018'
isi: 1
keyword:
- optimal
- state machine replication
- fallback
- asynchrony
- byzantine faults
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2103.03181
month: '07'
oa: 1
oa_version: Preprint
page: 187-190
publication: Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing
publication_identifier:
  isbn:
  - 9-781-4503-8548-0
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Brief announcement: Be prepared when network goes bad: An asynchronous view-change
  protocol'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10554'
abstract:
- lang: eng
  text: 'We present DAG-Rider, the first asynchronous Byzantine Atomic Broadcast protocol
    that achieves optimal resilience, optimal amortized communication complexity,
    and optimal time complexity. DAG-Rider is post-quantum safe and ensures that all
    values proposed by correct processes eventually get delivered. We construct DAG-Rider
    in two layers: In the first layer, processes reliably broadcast their proposals
    and build a structured Directed Acyclic Graph (DAG) of the communication among
    them. In the second layer, processes locally observe their DAGs and totally order
    all proposals with no extra communication.'
acknowledgement: "Oded Naor is grateful to the Technion Hiroshi Fujiwara Cyber-Security
  Research Center for providing a research grant. Part of Oded’s work was done while
  at Novi Research. This work was funded by the Novi team at Facebook. We also wish
  to thank the Novi Research team for valuable feedback, and in particular George
  Danezis, Alberto Sonnino, and Dahlia Malkhi.\r\n"
article_processing_charge: No
arxiv: 1
author:
- first_name: Idit
  full_name: Keidar, Idit
  last_name: Keidar
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
- first_name: Oded
  full_name: Naor, Oded
  last_name: Naor
- first_name: Alexander
  full_name: Spiegelman, Alexander
  last_name: Spiegelman
citation:
  ama: 'Keidar I, Kokoris Kogias E, Naor O, Spiegelman A. All You Need is DAG. In:
    <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i>.
    Association for Computing Machinery; 2021:165-175. doi:<a href="https://doi.org/10.1145/3465084.3467905">10.1145/3465084.3467905</a>'
  apa: 'Keidar, I., Kokoris Kogias, E., Naor, O., &#38; Spiegelman, A. (2021). All
    You Need is DAG. In <i>Proceedings of the 2021 ACM Symposium on Principles of
    Distributed Computing</i> (pp. 165–175). Virtual, Italy: Association for Computing
    Machinery. <a href="https://doi.org/10.1145/3465084.3467905">https://doi.org/10.1145/3465084.3467905</a>'
  chicago: Keidar, Idit, Eleftherios Kokoris Kogias, Oded Naor, and Alexander Spiegelman.
    “All You Need Is DAG.” In <i>Proceedings of the 2021 ACM Symposium on Principles
    of Distributed Computing</i>, 165–75. Association for Computing Machinery, 2021.
    <a href="https://doi.org/10.1145/3465084.3467905">https://doi.org/10.1145/3465084.3467905</a>.
  ieee: I. Keidar, E. Kokoris Kogias, O. Naor, and A. Spiegelman, “All You Need is
    DAG,” in <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing</i>, Virtual, Italy, 2021, pp. 165–175.
  ista: 'Keidar I, Kokoris Kogias E, Naor O, Spiegelman A. 2021. All You Need is DAG.
    Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing.
    PODC: Principles of Distributed Computing, 165–175.'
  mla: Keidar, Idit, et al. “All You Need Is DAG.” <i>Proceedings of the 2021 ACM
    Symposium on Principles of Distributed Computing</i>, Association for Computing
    Machinery, 2021, pp. 165–75, doi:<a href="https://doi.org/10.1145/3465084.3467905">10.1145/3465084.3467905</a>.
  short: I. Keidar, E. Kokoris Kogias, O. Naor, A. Spiegelman, in:, Proceedings of
    the 2021 ACM Symposium on Principles of Distributed Computing, Association for
    Computing Machinery, 2021, pp. 165–175.
conference:
  end_date: 2021-07-30
  location: Virtual, Italy
  name: 'PODC: Principles of Distributed Computing'
  start_date: 2021-07-26
date_created: 2021-12-16T13:21:13Z
date_published: 2021-07-21T00:00:00Z
date_updated: 2023-08-17T06:24:44Z
day: '21'
department:
- _id: ElKo
doi: 10.1145/3465084.3467905
external_id:
  arxiv:
  - '2102.08325'
  isi:
  - '000744439800016'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2102.08325
month: '07'
oa: 1
oa_version: Preprint
page: 165-175
publication: Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing
publication_identifier:
  isbn:
  - 978-1-4503-8548-0
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: All You Need is DAG
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
---
_id: '10559'
abstract:
- lang: eng
  text: Hole gases in planar germanium can have high mobilities in combination with
    strong spin-orbit interaction and electrically tunable g factors, and are therefore
    emerging as a promising platform for creating hybrid superconductor-semiconductor
    devices. A key challenge towards hybrid Ge-based quantum technologies is the design
    of high-quality interfaces and superconducting contacts that are robust against
    magnetic fields. In this work, by combining the assets of aluminum, which provides
    good contact to the Ge, and niobium, which has a significant superconducting gap,
    we demonstrate highly transparent low-disordered JoFETs with relatively large
    ICRN products that are capable of withstanding high magnetic fields. We furthermore
    demonstrate the ability of phase-biasing individual JoFETs, opening up an avenue
    to explore topological superconductivity in planar Ge. The persistence of superconductivity
    in the reported hybrid devices beyond 1.8 T paves the way towards integrating
    spin qubits and proximity-induced superconductivity on the same chip.
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
acknowledgement: This research and related results were made possible with the support
  of the NOMIS Foundation. This research was supported by the Scientific Service Units
  of IST Austria through resources provided by the MIBA Machine Shop and the nanofabrication
  facility, the European Union's Horizon 2020 research and innovation program under
  the Marie Sklodowska-Curie Grant agreement No. 844511 Grant Agreement No. 862046.
  ICN2 acknowledge funding from Generalitat de Catalunya 2017 SGR 327. ICN2 is supported
  by the Severo Ochoa program from Spanish MINECO (Grant No. SEV-2017-0706) and is
  funded by the CERCA Programme/Generalitat de Catalunya. Part of the present work
  has been performed in the framework of Universitat Autnoma de Barcelona Materials
  Science PhD program. The HAADF-STEM microscopy was conducted in the Laboratorio
  de Microscopias Avanzadas at Instituto de Nanociencia de Aragon-Universidad de Zaragoza.
  Authors acknowledge the LMA-INA for offering access to their instruments and expertise.
  We acknowledge support from CSIC Research Platform on Quantum Technologies PTI-001.
  This project has received funding from the European Union's Horizon 2020 research
  and innovation programme under Grant Agreement No. 823717 ESTEEM3. M.B. acknowledges
  support from SUR Generalitat de Catalunya and the EU Social Fund; project ref. 2020
  FI 00103. G.S. and M.V. acknowledge support through a projectruimte grant associated
  with the Netherlands Organization of Scientific Research (NWO). J.D. acknowledges
  support through FRIPRO-project 274853, which is funded by the Research Council of
  Norway.
article_number: L022005
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Kushagra
  full_name: Aggarwal, Kushagra
  id: b22ab905-3539-11eb-84c3-fc159dcd79cb
  last_name: Aggarwal
  orcid: 0000-0001-9985-9293
- first_name: Andrea C
  full_name: Hofmann, Andrea C
  id: 340F461A-F248-11E8-B48F-1D18A9856A87
  last_name: Hofmann
- first_name: Daniel
  full_name: Jirovec, Daniel
  id: 4C473F58-F248-11E8-B48F-1D18A9856A87
  last_name: Jirovec
  orcid: 0000-0002-7197-4801
- first_name: Ivan
  full_name: Prieto Gonzalez, Ivan
  id: 2A307FE2-F248-11E8-B48F-1D18A9856A87
  last_name: Prieto Gonzalez
  orcid: 0000-0002-7370-5357
- first_name: Amir
  full_name: Sammak, Amir
  last_name: Sammak
- first_name: Marc
  full_name: Botifoll, Marc
  last_name: Botifoll
- first_name: Sara
  full_name: Martí-Sánchez, Sara
  last_name: Martí-Sánchez
- first_name: Menno
  full_name: Veldhorst, Menno
  last_name: Veldhorst
- first_name: Jordi
  full_name: Arbiol, Jordi
  last_name: Arbiol
- first_name: Giordano
  full_name: Scappucci, Giordano
  last_name: Scappucci
- first_name: Jeroen
  full_name: Danon, Jeroen
  last_name: Danon
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
citation:
  ama: Aggarwal K, Hofmann AC, Jirovec D, et al. Enhancement of proximity-induced
    superconductivity in a planar Ge hole gas. <i>Physical Review Research</i>. 2021;3(2).
    doi:<a href="https://doi.org/10.1103/physrevresearch.3.l022005">10.1103/physrevresearch.3.l022005</a>
  apa: Aggarwal, K., Hofmann, A. C., Jirovec, D., Prieto Gonzalez, I., Sammak, A.,
    Botifoll, M., … Katsaros, G. (2021). Enhancement of proximity-induced superconductivity
    in a planar Ge hole gas. <i>Physical Review Research</i>. American Physical Society.
    <a href="https://doi.org/10.1103/physrevresearch.3.l022005">https://doi.org/10.1103/physrevresearch.3.l022005</a>
  chicago: Aggarwal, Kushagra, Andrea C Hofmann, Daniel Jirovec, Ivan Prieto Gonzalez,
    Amir Sammak, Marc Botifoll, Sara Martí-Sánchez, et al. “Enhancement of Proximity-Induced
    Superconductivity in a Planar Ge Hole Gas.” <i>Physical Review Research</i>. American
    Physical Society, 2021. <a href="https://doi.org/10.1103/physrevresearch.3.l022005">https://doi.org/10.1103/physrevresearch.3.l022005</a>.
  ieee: K. Aggarwal <i>et al.</i>, “Enhancement of proximity-induced superconductivity
    in a planar Ge hole gas,” <i>Physical Review Research</i>, vol. 3, no. 2. American
    Physical Society, 2021.
  ista: Aggarwal K, Hofmann AC, Jirovec D, Prieto Gonzalez I, Sammak A, Botifoll M,
    Martí-Sánchez S, Veldhorst M, Arbiol J, Scappucci G, Danon J, Katsaros G. 2021.
    Enhancement of proximity-induced superconductivity in a planar Ge hole gas. Physical
    Review Research. 3(2), L022005.
  mla: Aggarwal, Kushagra, et al. “Enhancement of Proximity-Induced Superconductivity
    in a Planar Ge Hole Gas.” <i>Physical Review Research</i>, vol. 3, no. 2, L022005,
    American Physical Society, 2021, doi:<a href="https://doi.org/10.1103/physrevresearch.3.l022005">10.1103/physrevresearch.3.l022005</a>.
  short: K. Aggarwal, A.C. Hofmann, D. Jirovec, I. Prieto Gonzalez, A. Sammak, M.
    Botifoll, S. Martí-Sánchez, M. Veldhorst, J. Arbiol, G. Scappucci, J. Danon, G.
    Katsaros, Physical Review Research 3 (2021).
corr_author: '1'
date_created: 2021-12-16T18:50:57Z
date_published: 2021-04-15T00:00:00Z
date_updated: 2025-04-15T08:38:16Z
day: '15'
ddc:
- '620'
department:
- _id: GeKa
doi: 10.1103/physrevresearch.3.l022005
ec_funded: 1
external_id:
  arxiv:
  - '2012.00322'
file:
- access_level: open_access
  checksum: 60a1bc9c9b616b1b155044bb8cfc6484
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-12-17T08:12:37Z
  date_updated: 2021-12-17T08:12:37Z
  file_id: '10561'
  file_name: 2021_PhysRevResearch_Aggarwal.pdf
  file_size: 1917512
  relation: main_file
  success: 1
file_date_updated: 2021-12-17T08:12:37Z
has_accepted_license: '1'
intvolume: '         3'
issue: '2'
keyword:
- general engineering
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 26A151DA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '844511'
  name: Majorana bound states in Ge/SiGe heterostructures
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862046'
  name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
publication: Physical Review Research
publication_identifier:
  issn:
  - 2643-1564
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '8834'
    relation: research_data
    status: public
  - id: '8831'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Enhancement of proximity-induced superconductivity in a planar Ge hole gas
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 3
year: '2021'
...
---
_id: '10565'
abstract:
- lang: eng
  text: 'Enzymatic digestion of the extracellular matrix with chondroitinase-ABC reinstates
    juvenile-like plasticity in the adult cortex as it also disassembles the perineuronal
    nets (PNNs). The disadvantage of the enzyme is that it must be applied intracerebrally
    and it degrades the ECM for several weeks. Here, we provide two minimally invasive
    and transient protocols for microglia-enabled PNN disassembly in mouse cortex:
    repeated treatment with ketamine-xylazine-acepromazine (KXA) anesthesia and 60-Hz
    light entrainment. We also discuss how to analyze PNNs within microglial endosomes-lysosomes.
    For complete details on the use and execution of this protocol, please refer to
    Venturino et al. (2021).'
acknowledged_ssus:
- _id: Bio
acknowledgement: This research was supported by the European Research Council (grant
  715571 to S.S.). We thank Rouven Schulz, Michael Schunn, Claudia Gold, Gabriel Krens,
  Sarah Gorkiewicz, Margaret Maes, Jürgen Siegert, Marco Benevento, and Sara Oakeley
  for comments on the manuscript and the IST Austria Bioimaging Facility for the technical
  support.
article_number: '101012'
article_processing_charge: Yes
article_type: original
author:
- first_name: Alessandro
  full_name: Venturino, Alessandro
  id: 41CB84B2-F248-11E8-B48F-1D18A9856A87
  last_name: Venturino
  orcid: 0000-0003-2356-9403
- first_name: Sandra
  full_name: Siegert, Sandra
  id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
  last_name: Siegert
  orcid: 0000-0001-8635-0877
citation:
  ama: Venturino A, Siegert S. Minimally invasive protocols and quantification for
    microglia-mediated perineuronal net disassembly in mouse brain. <i>STAR Protocols</i>.
    2021;2(4). doi:<a href="https://doi.org/10.1016/j.xpro.2021.101012">10.1016/j.xpro.2021.101012</a>
  apa: Venturino, A., &#38; Siegert, S. (2021). Minimally invasive protocols and quantification
    for microglia-mediated perineuronal net disassembly in mouse brain. <i>STAR Protocols</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.xpro.2021.101012">https://doi.org/10.1016/j.xpro.2021.101012</a>
  chicago: Venturino, Alessandro, and Sandra Siegert. “Minimally Invasive Protocols
    and Quantification for Microglia-Mediated Perineuronal Net Disassembly in Mouse
    Brain.” <i>STAR Protocols</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.xpro.2021.101012">https://doi.org/10.1016/j.xpro.2021.101012</a>.
  ieee: A. Venturino and S. Siegert, “Minimally invasive protocols and quantification
    for microglia-mediated perineuronal net disassembly in mouse brain,” <i>STAR Protocols</i>,
    vol. 2, no. 4. Elsevier, 2021.
  ista: Venturino A, Siegert S. 2021. Minimally invasive protocols and quantification
    for microglia-mediated perineuronal net disassembly in mouse brain. STAR Protocols.
    2(4), 101012.
  mla: Venturino, Alessandro, and Sandra Siegert. “Minimally Invasive Protocols and
    Quantification for Microglia-Mediated Perineuronal Net Disassembly in Mouse Brain.”
    <i>STAR Protocols</i>, vol. 2, no. 4, 101012, Elsevier, 2021, doi:<a href="https://doi.org/10.1016/j.xpro.2021.101012">10.1016/j.xpro.2021.101012</a>.
  short: A. Venturino, S. Siegert, STAR Protocols 2 (2021).
date_created: 2021-12-19T23:01:32Z
date_published: 2021-12-17T00:00:00Z
date_updated: 2025-05-14T11:26:30Z
day: '17'
ddc:
- '573'
department:
- _id: SaSi
doi: 10.1016/j.xpro.2021.101012
ec_funded: 1
file:
- access_level: open_access
  checksum: 9ea2501056c5df99e84726b845e9b976
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-12-20T08:58:40Z
  date_updated: 2021-12-20T08:58:40Z
  file_id: '10570'
  file_name: 2021_STARProt_Venturino.pdf
  file_size: 6207060
  relation: main_file
  success: 1
file_date_updated: 2021-12-20T08:58:40Z
has_accepted_license: '1'
intvolume: '         2'
issue: '4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25D4A630-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '715571'
  name: Microglia action towards neuronal circuit formation and function in health
    and disease
publication: STAR Protocols
publication_identifier:
  eissn:
  - 2666-1667
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Minimally invasive protocols and quantification for microglia-mediated perineuronal
  net disassembly in mouse brain
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2021'
...
---
_id: '10568'
abstract:
- lang: eng
  text: Genetic adaptation and phenotypic plasticity facilitate the migration into
    new habitats and enable organisms to cope with a rapidly changing environment.
    In contrast to genetic adaptation that spans multiple generations as an evolutionary
    process, phenotypic plasticity allows acclimation within the life-time of an organism.
    Genetic adaptation and phenotypic plasticity are usually studied in isolation,
    however, only by including their interactive impact, we can understand acclimation
    and adaptation in nature. We aimed to explore the contribution of adaptation and
    plasticity in coping with an abiotic (salinity) and a biotic (Vibrio bacteria)
    stressor using six different populations of the broad-nosed pipefish Syngnathus
    typhle that originated from either high [14–17 Practical Salinity Unit (PSU)]
    or low (7–11 PSU) saline environments along the German coastline of the Baltic
    Sea. We exposed wild caught animals, to either high (15 PSU) or low (7 PSU) salinity,
    representing native and novel salinity conditions and allowed animals to mate.
    After male pregnancy, offspring was split and each half was exposed to one of
    the two salinities and infected with Vibrio alginolyticus bacteria that were evolved
    at either of the two salinities in a fully reciprocal design. We investigated
    life-history traits of fathers and expression of 47 target genes in mothers and
    offspring. Pregnant males originating from high salinity exposed to low salinity
    were highly susceptible to opportunistic fungi infections resulting in decreased
    offspring size and number. In contrast, no signs of fungal infection were identified
    in fathers originating from low saline conditions suggesting that genetic adaptation
    has the potential to overcome the challenges encountered at low salinity. Offspring
    from parents with low saline origin survived better at low salinity suggesting
    genetic adaptation to low salinity. In addition, gene expression analyses of juveniles
    indicated patterns of local adaptation, trans-generational plasticity and developmental
    plasticity. In conclusion, our study suggests that pipefish are locally adapted
    to the low salinity in their environment, however, they are retaining phenotypic
    plasticity, which allows them to also cope with ancestral salinity levels and
    prevailing pathogens.
acknowledgement: We are grateful for the help of Kristina Dauven, Andreas Ebner, Janina
  Röckner, and Paulina Urban for fish collection in the field and fish maintenance.
  Furthermore, we thank Fabian Wendt for setting up the aquaria system and Tatjana
  Liese, Paulina Urban, Jakob Gismann, and Thorsten Reusch for support with DNA extraction
  and analysis of pipefish population structure. The authors acknowledge support of
  Isabel Tanger, Agnes Piecyk, Jonas Müller, Grace Walls, Sebastian Albrecht, Julia
  Böge, and Julia Stefanschitz for their support in preparing cDNA and running of
  Fluidigm chips. A special thank goes to Diana Gill for general lab support, ordering
  materials and just being the good spirit of our molecular lab, to Till Bayer for
  bioinformatics support and to Melanie Heckwolf for fruitful discussion and feedback
  on the manuscript. HG is very grateful for inspirational office space with ocean
  view provided by Lisa Hentschel and family. This manuscript has been released as
  a pre-print at BIORXIV.
article_number: '626442'
article_processing_charge: No
article_type: original
author:
- first_name: Henry
  full_name: Goehlich, Henry
  last_name: Goehlich
- first_name: Linda
  full_name: Sartoris, Linda
  id: 2B9284CA-F248-11E8-B48F-1D18A9856A87
  last_name: Sartoris
- first_name: Kim-Sara
  full_name: Wagner, Kim-Sara
  last_name: Wagner
- first_name: Carolin C.
  full_name: Wendling, Carolin C.
  last_name: Wendling
- first_name: Olivia
  full_name: Roth, Olivia
  last_name: Roth
citation:
  ama: Goehlich H, Sartoris L, Wagner K-S, Wendling CC, Roth O. Pipefish locally adapted
    to low salinity in the Baltic Sea retain phenotypic plasticity to cope with ancestral
    salinity levels. <i>Frontiers in Ecology and Evolution</i>. 2021;9. doi:<a href="https://doi.org/10.3389/fevo.2021.626442">10.3389/fevo.2021.626442</a>
  apa: Goehlich, H., Sartoris, L., Wagner, K.-S., Wendling, C. C., &#38; Roth, O.
    (2021). Pipefish locally adapted to low salinity in the Baltic Sea retain phenotypic
    plasticity to cope with ancestral salinity levels. <i>Frontiers in Ecology and
    Evolution</i>. Frontiers Media. <a href="https://doi.org/10.3389/fevo.2021.626442">https://doi.org/10.3389/fevo.2021.626442</a>
  chicago: Goehlich, Henry, Linda Sartoris, Kim-Sara Wagner, Carolin C. Wendling,
    and Olivia Roth. “Pipefish Locally Adapted to Low Salinity in the Baltic Sea Retain
    Phenotypic Plasticity to Cope with Ancestral Salinity Levels.” <i>Frontiers in
    Ecology and Evolution</i>. Frontiers Media, 2021. <a href="https://doi.org/10.3389/fevo.2021.626442">https://doi.org/10.3389/fevo.2021.626442</a>.
  ieee: H. Goehlich, L. Sartoris, K.-S. Wagner, C. C. Wendling, and O. Roth, “Pipefish
    locally adapted to low salinity in the Baltic Sea retain phenotypic plasticity
    to cope with ancestral salinity levels,” <i>Frontiers in Ecology and Evolution</i>,
    vol. 9. Frontiers Media, 2021.
  ista: Goehlich H, Sartoris L, Wagner K-S, Wendling CC, Roth O. 2021. Pipefish locally
    adapted to low salinity in the Baltic Sea retain phenotypic plasticity to cope
    with ancestral salinity levels. Frontiers in Ecology and Evolution. 9, 626442.
  mla: Goehlich, Henry, et al. “Pipefish Locally Adapted to Low Salinity in the Baltic
    Sea Retain Phenotypic Plasticity to Cope with Ancestral Salinity Levels.” <i>Frontiers
    in Ecology and Evolution</i>, vol. 9, 626442, Frontiers Media, 2021, doi:<a href="https://doi.org/10.3389/fevo.2021.626442">10.3389/fevo.2021.626442</a>.
  short: H. Goehlich, L. Sartoris, K.-S. Wagner, C.C. Wendling, O. Roth, Frontiers
    in Ecology and Evolution 9 (2021).
date_created: 2021-12-20T07:53:19Z
date_published: 2021-03-25T00:00:00Z
date_updated: 2023-08-17T06:27:22Z
day: '25'
ddc:
- '597'
department:
- _id: SyCr
doi: 10.3389/fevo.2021.626442
external_id:
  isi:
  - '000637736300001'
file:
- access_level: open_access
  checksum: 8d6e2b767bb0240a9b5a3a3555be51fd
  content_type: application/pdf
  creator: alisjak
  date_created: 2021-12-20T10:44:20Z
  date_updated: 2021-12-20T10:44:20Z
  file_id: '10572'
  file_name: 2021_Frontiers_Goehlich.pdf
  file_size: 3175085
  relation: main_file
  success: 1
file_date_updated: 2021-12-20T10:44:20Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
keyword:
- ecology
- evolution
- behavior and systematics
- trans-generational plasticity
- genetic adaptation
- local adaptation
- phenotypic plasticity
- Baltic Sea
- climate change
- salinity
- syngnathids
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Frontiers in Ecology and Evolution
publication_identifier:
  issn:
  - 2296-701X
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: Pipefish locally adapted to low salinity in the Baltic Sea retain phenotypic
  plasticity to cope with ancestral salinity levels
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2021'
...
---
_id: '10569'
abstract:
- lang: eng
  text: 'For animals to survive until reproduction, it is crucial that juveniles successfully
    detect potential predators and respond with appropriate behavior. The recognition
    of cues originating from predators can be innate or learned. Cues of various modalities
    might be used alone or in multi-modal combinations to detect and distinguish predators
    but studies investigating multi-modal integration in predator avoidance are scarce.
    Here, we used wild, naive tadpoles of the Neotropical poison frog Allobates femoralis
    ( Boulenger, 1884) to test their reaction to cues with two modalities from two
    different sympatrically occurring potential predators: heterospecific predatory
    Dendrobates tinctorius tadpoles and dragonfly larvae. We presented A. femoralis
    tadpoles with olfactory or visual cues, or a combination of the two, and compared
    their reaction to a water control in a between-individual design. In our trials,
    A. femoralis tadpoles reacted to multi-modal stimuli (a combination of visual
    and chemical information) originating from dragonfly larvae with avoidance but
    showed no reaction to uni-modal cues or cues from heterospecific tadpoles. In
    addition, visual cues from conspecifics increased swimming activity while cues
    from predators had no effect on tadpole activity. Our results show that A. femoralis
    tadpoles can innately recognize some predators and probably need both visual and
    chemical information to effectively avoid them. This is the first study looking
    at anti-predator behavior in poison frog tadpoles. We discuss how parental care
    might influence the expression of predator avoidance responses in tadpoles.'
acknowledgement: We are grateful to Véronique Helfer, Walter Hödl, Lisa Schretzmeyer
  and Julia Wotke, who assisted with fieldwork in French Guiana. This work was supported
  by the Austrian Science Fund (FWF) [P24788, T699 and P31518 to E.R.; P33728 to M.R.;
  J3827 to Thomas Bugnyar, Tecumseh Fitch and Ludwig Huber]; and by the Austrian Bundesministerium
  für Wissenschaft, Forschung und Wirtschaft [IS761001 to J.O. (Tecumseh Fitch, Thomas
  Bugnyar and Ludwig Huber)]. A.P. was supported by the European Union's Horizon 2020
  research and innovation programme under the Marie Sklodowska-Curie grant agreement
  no. 835530. S.A.R. was supported by the HT faculty, Lund University. We thank the
  CNRS Nouragues Ecological Research Station, which benefited from the ‘Investissement
  d'Avenir’ grants managed by the Agence Nationale de la Recherche (AnaEE France ANR-11-INBS-0001;
  Labex CEBA ANR-10-LABX-25-01). Open access funding provided by University of Vienna.
  Deposited in PMC for immediate release.
article_number: jeb243647
article_processing_charge: No
article_type: original
author:
- first_name: B
  full_name: Szabo, B
  last_name: Szabo
- first_name: R
  full_name: Mangione, R
  last_name: Mangione
- first_name: M
  full_name: Rath, M
  last_name: Rath
- first_name: A
  full_name: Pašukonis, A
  last_name: Pašukonis
- first_name: SA
  full_name: Reber, SA
  last_name: Reber
- first_name: Jinook
  full_name: Oh, Jinook
  id: 403169A4-080F-11EA-9993-BF3F3DDC885E
  last_name: Oh
  orcid: 0000-0001-7425-2372
- first_name: M
  full_name: Ringler, M
  last_name: Ringler
- first_name: E
  full_name: Ringler, E
  last_name: Ringler
citation:
  ama: Szabo B, Mangione R, Rath M, et al. Naïve poison frog tadpoles use bi-modal
    cues to avoid insect predators but not heterospecific predatory tadpoles. <i>Journal
    of Experimental Biology</i>. 2021;224(24). doi:<a href="https://doi.org/10.1242/jeb.243647">10.1242/jeb.243647</a>
  apa: Szabo, B., Mangione, R., Rath, M., Pašukonis, A., Reber, S., Oh, J., … Ringler,
    E. (2021). Naïve poison frog tadpoles use bi-modal cues to avoid insect predators
    but not heterospecific predatory tadpoles. <i>Journal of Experimental Biology</i>.
    The Company of Biologists. <a href="https://doi.org/10.1242/jeb.243647">https://doi.org/10.1242/jeb.243647</a>
  chicago: Szabo, B, R Mangione, M Rath, A Pašukonis, SA Reber, Jinook Oh, M Ringler,
    and E Ringler. “Naïve Poison Frog Tadpoles Use Bi-Modal Cues to Avoid Insect Predators
    but Not Heterospecific Predatory Tadpoles.” <i>Journal of Experimental Biology</i>.
    The Company of Biologists, 2021. <a href="https://doi.org/10.1242/jeb.243647">https://doi.org/10.1242/jeb.243647</a>.
  ieee: B. Szabo <i>et al.</i>, “Naïve poison frog tadpoles use bi-modal cues to avoid
    insect predators but not heterospecific predatory tadpoles,” <i>Journal of Experimental
    Biology</i>, vol. 224, no. 24. The Company of Biologists, 2021.
  ista: Szabo B, Mangione R, Rath M, Pašukonis A, Reber S, Oh J, Ringler M, Ringler
    E. 2021. Naïve poison frog tadpoles use bi-modal cues to avoid insect predators
    but not heterospecific predatory tadpoles. Journal of Experimental Biology. 224(24),
    jeb243647.
  mla: Szabo, B., et al. “Naïve Poison Frog Tadpoles Use Bi-Modal Cues to Avoid Insect
    Predators but Not Heterospecific Predatory Tadpoles.” <i>Journal of Experimental
    Biology</i>, vol. 224, no. 24, jeb243647, The Company of Biologists, 2021, doi:<a
    href="https://doi.org/10.1242/jeb.243647">10.1242/jeb.243647</a>.
  short: B. Szabo, R. Mangione, M. Rath, A. Pašukonis, S. Reber, J. Oh, M. Ringler,
    E. Ringler, Journal of Experimental Biology 224 (2021).
date_created: 2021-12-20T07:54:22Z
date_published: 2021-12-16T00:00:00Z
date_updated: 2024-10-21T06:02:05Z
day: '16'
ddc:
- '573'
department:
- _id: SyCr
doi: 10.1242/jeb.243647
external_id:
  isi:
  - '000738259300013'
  pmid:
  - '34845497'
file:
- access_level: open_access
  checksum: 75d13a5ec8e3b90e3bc02bd8a9c17eef
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-12-20T10:14:14Z
  date_updated: 2021-12-20T10:14:14Z
  file_id: '10571'
  file_name: 2021_JExpBio_Szabo.pdf
  file_size: 607096
  relation: main_file
  success: 1
file_date_updated: 2021-12-20T10:14:14Z
has_accepted_license: '1'
intvolume: '       224'
isi: 1
issue: '24'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Experimental Biology
publication_identifier:
  eissn:
  - 1477-9145
  issn:
  - 0022-0949
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Naïve poison frog tadpoles use bi-modal cues to avoid insect predators but
  not heterospecific predatory tadpoles
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 224
year: '2021'
...
