---
OA_place: repository
OA_type: green
_id: '19771'
abstract:
- lang: eng
text: "This artifact allows to review and reproduce the Isabelle proofs and practical
experiments from the paper *Fixed Point Certificates for Reachability and Expected
Rewards in MDPs*.\r\nThe contents are two-fold:\r\nFirst, the artifact contains
a formally verified certificate checker for the certificates presented in the
paper.\r\nThe formal Isabelle/HOL proofs of the background theory can be inspected,
checked by Isabelle and the code extraction can be retraced.\r\n\r\nSecond, the
artifact contains a modified version of the model checking tool `Storm` with support
for certificate generation. Together with the provided scripts and benchmark files,
this allows to reproduce the experiments from the paper.\r\nAn appropriate subset
of the experiments is given to allow a review in a timely manner. In addition,
original logfiles from our experiments are provided, allowing a detailed inspection.\r\n\r\nThe
package includes convenient installation scripts for [the TACAS 2023 VM](https://doi.org/10.5281/zenodo.7113223)
(based on Ubuntu 22.04).\r\nA native installation on Linux or macOS systems (including
the newer ARM-based machines) is also possible."
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Tim
full_name: Quatmann, Tim
last_name: Quatmann
- first_name: Maximilian
full_name: Schäffeler, Maximilian
last_name: Schäffeler
- first_name: Maximilian
full_name: Weininger, Maximilian
id: 02ab0197-cc70-11ed-ab61-918e71f56881
last_name: Weininger
- first_name: Tobias
full_name: Winkler, Tobias
last_name: Winkler
- first_name: Daniel
full_name: Zilken, Daniel
id: d8ebc24a-3f98-11f0-9044-8296d4f39ab3
last_name: Zilken
citation:
ama: 'Chatterjee K, Quatmann T, Schäffeler M, Weininger M, Winkler T, Zilken D.
Artifact: Fixed point certificates for reachability and expected rewards in MDPs.
2025. doi:10.5281/ZENODO.14626585'
apa: 'Chatterjee, K., Quatmann, T., Schäffeler, M., Weininger, M., Winkler, T.,
& Zilken, D. (2025). Artifact: Fixed point certificates for reachability and
expected rewards in MDPs. Zenodo. https://doi.org/10.5281/ZENODO.14626585'
chicago: 'Chatterjee, Krishnendu, Tim Quatmann, Maximilian Schäffeler, Maximilian
Weininger, Tobias Winkler, and Daniel Zilken. “Artifact: Fixed Point Certificates
for Reachability and Expected Rewards in MDPs.” Zenodo, 2025. https://doi.org/10.5281/ZENODO.14626585.'
ieee: 'K. Chatterjee, T. Quatmann, M. Schäffeler, M. Weininger, T. Winkler, and
D. Zilken, “Artifact: Fixed point certificates for reachability and expected rewards
in MDPs.” Zenodo, 2025.'
ista: 'Chatterjee K, Quatmann T, Schäffeler M, Weininger M, Winkler T, Zilken D.
2025. Artifact: Fixed point certificates for reachability and expected rewards
in MDPs, Zenodo, 10.5281/ZENODO.14626585.'
mla: 'Chatterjee, Krishnendu, et al. Artifact: Fixed Point Certificates for Reachability
and Expected Rewards in MDPs. Zenodo, 2025, doi:10.5281/ZENODO.14626585.'
short: K. Chatterjee, T. Quatmann, M. Schäffeler, M. Weininger, T. Winkler, D. Zilken,
(2025).
date_created: 2025-06-02T10:13:24Z
date_published: 2025-01-09T00:00:00Z
date_updated: 2025-06-02T10:55:35Z
day: '09'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.5281/ZENODO.14626585
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/ZENODO.14626585
month: '01'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '19743'
relation: used_in_publication
status: public
status: public
title: 'Artifact: Fixed point certificates for reachability and expected rewards in
MDPs'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '19776'
abstract:
- lang: eng
text: We use the circle method to prove that a density 1 of elements in Fq[t] are
representable as a sum of three cubes of essentially minimal degree from Fq[t],
assuming the Ratios Conjecture and that char(Fq)>3. Roughly speaking, to do so,
we upgrade an order of magnitude result to a full asymptotic formula that was
conjectured by Hooley in the number field setting.
acknowledgement: We thank Alexandra Florea for discussions on cubic Gauss sums over
function fields, in addition to the anonymous referee for helpful comments. While
working on this paper the first two authors were supported by a FWF grant (DOI 10.55776/P36278)
and the third author was supported by the European Union’s Horizon 2020 research
and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.
Open access funding provided by Institute of Science and Technology (IST Austria).
article_number: '65'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Jakob
full_name: Glas, Jakob
id: d6423cba-dc74-11ea-a0a7-ee61689ff5fb
last_name: Glas
- first_name: Victor
full_name: Wang, Victor
id: 76096395-aea4-11ed-a680-ab8ebbd3f1b9
last_name: Wang
orcid: 0000-0002-0704-7026
citation:
ama: Browning TD, Glas J, Wang V. Optimal sums of three cubes in Fq[t]. Mathematische
Zeitschrift. 2025;310(4). doi:10.1007/s00209-025-03765-z
apa: Browning, T. D., Glas, J., & Wang, V. (2025). Optimal sums of three cubes
in Fq[t]. Mathematische Zeitschrift. Springer Nature. https://doi.org/10.1007/s00209-025-03765-z
chicago: Browning, Timothy D, Jakob Glas, and Victor Wang. “Optimal Sums of Three
Cubes in Fq[T].” Mathematische Zeitschrift. Springer Nature, 2025. https://doi.org/10.1007/s00209-025-03765-z.
ieee: T. D. Browning, J. Glas, and V. Wang, “Optimal sums of three cubes in Fq[t],”
Mathematische Zeitschrift, vol. 310, no. 4. Springer Nature, 2025.
ista: Browning TD, Glas J, Wang V. 2025. Optimal sums of three cubes in Fq[t]. Mathematische
Zeitschrift. 310(4), 65.
mla: Browning, Timothy D., et al. “Optimal Sums of Three Cubes in Fq[T].” Mathematische
Zeitschrift, vol. 310, no. 4, 65, Springer Nature, 2025, doi:10.1007/s00209-025-03765-z.
short: T.D. Browning, J. Glas, V. Wang, Mathematische Zeitschrift 310 (2025).
corr_author: '1'
date_created: 2025-06-03T07:30:21Z
date_published: 2025-05-23T00:00:00Z
date_updated: 2025-09-30T12:43:41Z
day: '23'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.1007/s00209-025-03765-z
ec_funded: 1
external_id:
arxiv:
- '2408.03668 '
isi:
- '001494367000001'
file:
- access_level: open_access
checksum: 6f71e25740c28257bf89b8bf116c2b4d
content_type: application/pdf
creator: dernst
date_created: 2025-06-03T08:28:14Z
date_updated: 2025-06-03T08:28:14Z
file_id: '19782'
file_name: 2025_MathZeitschrift_Browning.pdf
file_size: 461622
relation: main_file
success: 1
file_date_updated: 2025-06-03T08:28:14Z
has_accepted_license: '1'
intvolume: ' 310'
isi: 1
issue: '4'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: bd8a4fdc-d553-11ed-ba76-80a0167441a3
grant_number: P36278
name: Rational curves via function field analytic number theory
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Mathematische Zeitschrift
publication_identifier:
eissn:
- 1432-1823
issn:
- 0025-5874
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal sums of three cubes in Fq[t]
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 310
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '15016'
abstract:
- lang: eng
text: Amphibians, by virtue of their phylogenetic position, provide invaluable insights
on nervous system evolution, development, and remodeling. The genetic toolkit
for amphibians, however, remains limited. Recombinant adeno-associated viral vectors
(AAVs) are a powerful alternative to transgenesis for labeling and manipulating
neurons. Although successful in mammals, AAVs have never been shown to transduce
amphibian cells efficiently. We screened AAVs in three amphibian species—the frogs
Xenopus laevis and Pelophylax bedriagae and the salamander Pleurodeles waltl—and
identified at least two AAV serotypes per species that transduce neurons. In developing
amphibians, AAVs labeled groups of neurons generated at the same time during development.
In the mature brain, AAVrg retrogradely traced long-range projections. Our study
introduces AAVs as a tool for amphibian research, establishes a generalizable
workflow for AAV screening in new species, and expands opportunities for cross-species
comparisons of nervous system development, function, and evolution.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
acknowledgement: 'We thank members of the Sweeney, Tosches, Shein-Idelson, Yamaguchi,
Kelley, and Cline Labs for their contributions to this project, discussion, and
support. We additionally thank the Beckman Institute CLOVER Center and Viviana Gradinaru
(Caltech), Kimberly Ritola (UNC NeuroTools), and Flavia Gomez-Leite (ISTA Viral
Core) for AAV production and consultation; Andras Simon and Alberto Joven (Karolinska
Institute) for feedback; Elizabeth Bagnato-Cohen (Columbia) for project coordination;
our animal care and imaging facilities; the amphibian stock centers (NXR, EXRC,
and XenopusExpress); and our funding sources: NSF IOS 2110086 (D.B.K., L.B.S., M.A.T.,
A.Y., and H.T.C.); US-Israel Binational Science Foundation (BSF) 2020702 (M.S.-I.);
FTI Strategy Lower Austria Dissertation FT121-D-046 (D.V.); Horizon Europe ERC Starting
Grant 101041551 and Special Research Programme (SFB) of the Austrian Science Fund
(FWF) project F7814-B (L.B.S.); NIH grant R35GM146973, Rita Allen Foundation Award
GA_032522_FE, and CZI Ben Barres Early Career Acceleration Award 2023-331758 (M.A.T.);
EMBO Long-Term Fellowship ALTF 874-2021 (A.D.); and NSF GRFP DGE 2036197 (E.C.B.J.).'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Eliza C.B.
full_name: Jaeger, Eliza C.B.
last_name: Jaeger
- first_name: David
full_name: Vijatovic, David
id: cf391e77-ec3c-11ea-a124-d69323410b58
last_name: Vijatovic
- first_name: Astrid
full_name: Deryckere, Astrid
last_name: Deryckere
- first_name: Nikol
full_name: Zorin, Nikol
last_name: Zorin
- first_name: Akemi L.
full_name: Nguyen, Akemi L.
last_name: Nguyen
- first_name: Georgiy
full_name: Ivanian, Georgiy
id: eaf2b366-cfd1-11ee-bbdf-c8790f800a05
last_name: Ivanian
- first_name: Jamie
full_name: Woych, Jamie
last_name: Woych
- first_name: Rebecca C
full_name: Arnold, Rebecca C
id: d6cce458-14c9-11ed-a755-c1c8fc6fde6f
last_name: Arnold
- first_name: Alonso
full_name: Ortega Gurrola, Alonso
last_name: Ortega Gurrola
- first_name: Arik
full_name: Shvartsman, Arik
last_name: Shvartsman
- first_name: Francesca
full_name: Barbieri, Francesca
id: a9492887-8972-11ed-ae7b-bfae10998254
last_name: Barbieri
- first_name: Florina-Alexandra
full_name: Toma, Florina-Alexandra
id: 85dd99f2-15b2-11ec-abd3-d1ae4d57f3b5
last_name: Toma
- first_name: Gary J.
full_name: Gorbsky, Gary J.
last_name: Gorbsky
- first_name: Marko E.
full_name: Horb, Marko E.
last_name: Horb
- first_name: Hollis T.
full_name: Cline, Hollis T.
last_name: Cline
- first_name: Timothy F.
full_name: Shay, Timothy F.
last_name: Shay
- first_name: Darcy B.
full_name: Kelley, Darcy B.
last_name: Kelley
- first_name: Ayako
full_name: Yamaguchi, Ayako
last_name: Yamaguchi
- first_name: Mark
full_name: Shein-Idelson, Mark
last_name: Shein-Idelson
- first_name: Maria Antonietta
full_name: Tosches, Maria Antonietta
last_name: Tosches
- first_name: Lora Beatrice Jaeger
full_name: Sweeney, Lora Beatrice Jaeger
id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
last_name: Sweeney
orcid: 0000-0001-9242-5601
citation:
ama: Jaeger ECB, Vijatovic D, Deryckere A, et al. Adeno-associated viral tools to
trace neural development and connectivity across amphibians. Developmental
Cell. 2025;60(5):794-812.e6. doi:10.1016/j.devcel.2024.10.025
apa: Jaeger, E. C. B., Vijatovic, D., Deryckere, A., Zorin, N., Nguyen, A. L., Ivanian,
G., … Sweeney, L. B. (2025). Adeno-associated viral tools to trace neural development
and connectivity across amphibians. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2024.10.025
chicago: Jaeger, Eliza C.B., David Vijatovic, Astrid Deryckere, Nikol Zorin, Akemi
L. Nguyen, Georgiy Ivanian, Jamie Woych, et al. “Adeno-Associated Viral Tools
to Trace Neural Development and Connectivity across Amphibians.” Developmental
Cell. Elsevier, 2025. https://doi.org/10.1016/j.devcel.2024.10.025.
ieee: E. C. B. Jaeger et al., “Adeno-associated viral tools to trace neural
development and connectivity across amphibians,” Developmental Cell, vol.
60, no. 5. Elsevier, p. 794–812.e6, 2025.
ista: Jaeger ECB, Vijatovic D, Deryckere A, Zorin N, Nguyen AL, Ivanian G, Woych
J, Arnold RC, Ortega Gurrola A, Shvartsman A, Barbieri F, Toma F-A, Gorbsky GJ,
Horb ME, Cline HT, Shay TF, Kelley DB, Yamaguchi A, Shein-Idelson M, Tosches MA,
Sweeney LB. 2025. Adeno-associated viral tools to trace neural development and
connectivity across amphibians. Developmental Cell. 60(5), 794–812.e6.
mla: Jaeger, Eliza C. B., et al. “Adeno-Associated Viral Tools to Trace Neural Development
and Connectivity across Amphibians.” Developmental Cell, vol. 60, no. 5,
Elsevier, 2025, p. 794–812.e6, doi:10.1016/j.devcel.2024.10.025.
short: E.C.B. Jaeger, D. Vijatovic, A. Deryckere, N. Zorin, A.L. Nguyen, G. Ivanian,
J. Woych, R.C. Arnold, A. Ortega Gurrola, A. Shvartsman, F. Barbieri, F.-A. Toma,
G.J. Gorbsky, M.E. Horb, H.T. Cline, T.F. Shay, D.B. Kelley, A. Yamaguchi, M.
Shein-Idelson, M.A. Tosches, L.B. Sweeney, Developmental Cell 60 (2025) 794–812.e6.
corr_author: '1'
date_created: 2024-02-20T09:20:32Z
date_published: 2025-03-10T00:00:00Z
date_updated: 2025-09-30T10:00:55Z
day: '10'
ddc:
- '570'
department:
- _id: LoSw
- _id: MaDe
- _id: GaNo
doi: 10.1016/j.devcel.2024.10.025
external_id:
isi:
- '001444798600001'
pmid:
- '39603234'
file:
- access_level: open_access
checksum: a83a4cb58f5941096d3ad91ca0172594
content_type: application/pdf
creator: dernst
date_created: 2025-06-04T05:43:27Z
date_updated: 2025-06-04T05:43:27Z
file_id: '19790'
file_name: 2025_DevelopmentalCell_Jaeger.pdf
file_size: 11936258
relation: main_file
success: 1
file_date_updated: 2025-06-04T05:43:27Z
has_accepted_license: '1'
intvolume: ' 60'
isi: 1
issue: '5'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 794-812.e6
pmid: 1
project:
- _id: bd73af52-d553-11ed-ba76-912049f0ac7a
grant_number: FTI21-D-046
name: Development of V1 interneuron diversity during swim-to-walk transition of
Xenopus metamorphosis
- _id: ebb66355-77a9-11ec-83b8-b8ac210a4dae
grant_number: '101041551'
name: Development and Evolution of Tetrapod Motor Circuits
- _id: 8da85f50-16d5-11f0-9cad-eab8b0ff6c9e
grant_number: F7814
name: 'Stem Cell Modulation in Neural Development and Regeneration/ P14-Swim-to-limb
transition: cell type to connection diversity'
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adeno-associated viral tools to trace neural development and connectivity across
amphibians
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 60
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '15121'
abstract:
- lang: eng
text: We present an auction algorithm using multiplicative instead of constant weight
updates to compute a (1-E)-approximate maximum weight matching (MWM) in a bipartite
graph with n vertices and m edges in time 0(mE-1), beating the running time of
the fastest known approximation algorithm of Duan and Pettie [JACM ’14] that runs
in 0(mE-1 log E-1). Our algorithm is very simple and it can be extended to give
a dynamic data structure that maintains a (1-E)-approximate maximum weight matching
under (1) one-sided vertex deletions (with incident edges) and (2) one-sided vertex
insertions (with incident edges sorted by weight) to the other side. The total
time time used is 0(mE-1), where m is the sum of the number of initially existing
and inserted edges.
acknowledgement: The first author thanks Chandra Chekuri for useful discussions about
this paper. This work was done in part at the University of Vienna. This project
has received funding from the European Research Council (ERC) under the European
Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101019564
“The Design of Modern Fully Dynamic Data Structures (MoDynStruct)” and from the
Austrian Science Fund (FWF) project “Fast Algorithms for a Reactive Network Layer
(ReactNet)”, P 33775-N, with additional funding from the netidee SCIENCE Stiftung,
2020–2024.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Da Wei
full_name: Zheng, Da Wei
last_name: Zheng
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: Zheng DW, Henzinger M. Multiplicative auction algorithm for approximate maximum
weight bipartite matching. Mathematical Programming. 2025;210:881-894.
doi:10.1007/s10107-024-02066-3
apa: Zheng, D. W., & Henzinger, M. (2025). Multiplicative auction algorithm
for approximate maximum weight bipartite matching. Mathematical Programming.
Springer Nature. https://doi.org/10.1007/s10107-024-02066-3
chicago: Zheng, Da Wei, and Monika Henzinger. “Multiplicative Auction Algorithm
for Approximate Maximum Weight Bipartite Matching.” Mathematical Programming.
Springer Nature, 2025. https://doi.org/10.1007/s10107-024-02066-3.
ieee: D. W. Zheng and M. Henzinger, “Multiplicative auction algorithm for approximate
maximum weight bipartite matching,” Mathematical Programming, vol. 210.
Springer Nature, pp. 881–894, 2025.
ista: Zheng DW, Henzinger M. 2025. Multiplicative auction algorithm for approximate
maximum weight bipartite matching. Mathematical Programming. 210, 881–894.
mla: Zheng, Da Wei, and Monika Henzinger. “Multiplicative Auction Algorithm for
Approximate Maximum Weight Bipartite Matching.” Mathematical Programming,
vol. 210, Springer Nature, 2025, pp. 881–94, doi:10.1007/s10107-024-02066-3.
short: D.W. Zheng, M. Henzinger, Mathematical Programming 210 (2025) 881–894.
corr_author: '1'
date_created: 2024-03-17T23:00:58Z
date_published: 2025-03-01T00:00:00Z
date_updated: 2025-09-09T12:39:58Z
day: '01'
department:
- _id: MoHe
doi: 10.1007/s10107-024-02066-3
ec_funded: 1
external_id:
arxiv:
- '2301.09217'
isi:
- '001176048100003'
intvolume: ' 210'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2301.09217
month: '03'
oa: 1
oa_version: Preprint
page: 881-894
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
call_identifier: H2020
grant_number: '101019564'
name: The design and evaluation of modern fully dynamic data structures
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
grant_number: P33775
name: Fast Algorithms for a Reactive Network Layer
publication: Mathematical Programming
publication_identifier:
eissn:
- 1436-4646
issn:
- 0025-5610
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '13236'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Multiplicative auction algorithm for approximate maximum weight bipartite matching
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 210
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '15128'
abstract:
- lang: eng
text: We prove a universal mesoscopic central limit theorem for linear eigenvalue
statistics of a Wigner-type matrix inside the bulk of the spectrum with compactly
supported twice continuously differentiable test functions. The main novel ingredient
is an optimal local law for the two-point function $T(z,\zeta)$ and a general
class of related quantities involving two resolvents at nearby spectral parameters.
- lang: fre
text: "On établit un théorème limite central universel pour les statistiques linéaires
mésoscopiques des valeurs propres d’une matrice de type Wigner au milieu du spectre,
avec des fonctions de classe \r\n et à support compact. La principale nouveauté
de cette approche est qu’elle repose sur une loi locale optimale pour la fonction
à deux points $T(z,\\zeta)$ , ainsi que pour une classe plus générale d’observables
impliquant deux résolvantes évaluées en des paramètres proches."
acknowledgement: "I would like to express my gratitude to László Erdős for suggesting
the project and supervising my work. I am also thankful to Yuanyuan Xu and Oleksii
Kolupaiev for many helpful discussions. Furthermore, I am grateful to Guillaume
Dubach for translating the abstract into French.\r\nThe author was supported by
the ERC Advanced Grant “RMTBeyond” No. 101020331."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Volodymyr
full_name: Riabov, Volodymyr
id: 1949f904-edfb-11eb-afb5-e2dfddabb93b
last_name: Riabov
citation:
ama: Riabov V. Mesoscopic eigenvalue statistics for Wigner-type matrices. Annales
de l’institut Henri Poincare (B) Probability and Statistics. 2025;61(1):129-154.
doi:10.1214/23-AIHP1438
apa: Riabov, V. (2025). Mesoscopic eigenvalue statistics for Wigner-type matrices.
Annales de l’institut Henri Poincare (B) Probability and Statistics. Institute
of Mathematical Statistics. https://doi.org/10.1214/23-AIHP1438
chicago: Riabov, Volodymyr. “Mesoscopic Eigenvalue Statistics for Wigner-Type Matrices.”
Annales de l’institut Henri Poincare (B) Probability and Statistics. Institute
of Mathematical Statistics, 2025. https://doi.org/10.1214/23-AIHP1438.
ieee: V. Riabov, “Mesoscopic eigenvalue statistics for Wigner-type matrices,” Annales
de l’institut Henri Poincare (B) Probability and Statistics, vol. 61, no.
1. Institute of Mathematical Statistics, pp. 129–154, 2025.
ista: Riabov V. 2025. Mesoscopic eigenvalue statistics for Wigner-type matrices.
Annales de l’institut Henri Poincare (B) Probability and Statistics. 61(1), 129–154.
mla: Riabov, Volodymyr. “Mesoscopic Eigenvalue Statistics for Wigner-Type Matrices.”
Annales de l’institut Henri Poincare (B) Probability and Statistics, vol.
61, no. 1, Institute of Mathematical Statistics, 2025, pp. 129–54, doi:10.1214/23-AIHP1438.
short: V. Riabov, Annales de l’institut Henri Poincare (B) Probability and Statistics
61 (2025) 129–154.
corr_author: '1'
date_created: 2024-03-20T09:41:04Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2025-05-19T13:54:31Z
day: '01'
department:
- _id: GradSch
- _id: LaEr
doi: 10.1214/23-AIHP1438
ec_funded: 1
external_id:
arxiv:
- '2301.01712'
isi:
- '001427953600004'
intvolume: ' 61'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2301.01712
month: '02'
oa: 1
oa_version: Preprint
page: 129-154
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
call_identifier: H2020
grant_number: '101020331'
name: Random matrices beyond Wigner-Dyson-Mehta
publication: Annales de l'institut Henri Poincare (B) Probability and Statistics
publication_identifier:
issn:
- 0246-0203
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mesoscopic eigenvalue statistics for Wigner-type matrices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 61
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '10011'
abstract:
- lang: eng
text: We propose a new weak solution concept for (two-phase) mean curvature flow
which enjoys both (unconditional) existence and (weak-strong) uniqueness properties.
These solutions are evolving varifolds, just as in Brakke's formulation, but are
coupled to the phase volumes by a simple transport equation. First, we show that,
in the exact same setup as in Ilmanen's proof [J. Differential Geom. 38, 417-461,
(1993)], any limit point of solutions to the Allen-Cahn equation is a varifold
solution in our sense. Second, we prove that any calibrated flow in the sense
of Fischer et al. [arXiv:2003.05478] - and hence any classical solution to mean
curvature flow-is unique in the class of our new varifold solutions. This is in
sharp contrast to the case of Brakke flows, which a priori may disappear at any
given time and are therefore fatally non-unique. Finally, we propose an extension
of the solution concept to the multi-phase case which is at least guaranteed to
satisfy a weak-strong uniqueness principle.
acknowledgement: This project has received funding from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme
(grant agreement No 948819), and from the Deutsche Forschungsgemeinschaft (DFG,
German Research Foundation) under Germany’s Excellence Strategy – EXC-2047/1 – 390685813.
The content of this paper was developed and parts of it were written during a visit
of the first author to the Hausdorff Center of Mathematics (HCM), University of
Bonn. The hospitality and the support of HCM are gratefully acknowledged.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sebastian
full_name: Hensel, Sebastian
id: 4D23B7DA-F248-11E8-B48F-1D18A9856A87
last_name: Hensel
orcid: 0000-0001-7252-8072
- first_name: Tim
full_name: Laux, Tim
last_name: Laux
citation:
ama: 'Hensel S, Laux T. A new varifold solution concept for mean curvature flow:
Convergence of the Allen-Cahn equation and weak-strong uniqueness. Journal
of Differential Geometry. 2025;130:209-268. doi:10.4310/jdg/1747065796'
apa: 'Hensel, S., & Laux, T. (2025). A new varifold solution concept for mean
curvature flow: Convergence of the Allen-Cahn equation and weak-strong uniqueness.
Journal of Differential Geometry. International Press. https://doi.org/10.4310/jdg/1747065796'
chicago: 'Hensel, Sebastian, and Tim Laux. “A New Varifold Solution Concept for
Mean Curvature Flow: Convergence of the Allen-Cahn Equation and Weak-Strong Uniqueness.”
Journal of Differential Geometry. International Press, 2025. https://doi.org/10.4310/jdg/1747065796.'
ieee: 'S. Hensel and T. Laux, “A new varifold solution concept for mean curvature
flow: Convergence of the Allen-Cahn equation and weak-strong uniqueness,” Journal
of Differential Geometry, vol. 130. International Press, pp. 209–268, 2025.'
ista: 'Hensel S, Laux T. 2025. A new varifold solution concept for mean curvature
flow: Convergence of the Allen-Cahn equation and weak-strong uniqueness. Journal
of Differential Geometry. 130, 209–268.'
mla: 'Hensel, Sebastian, and Tim Laux. “A New Varifold Solution Concept for Mean
Curvature Flow: Convergence of the Allen-Cahn Equation and Weak-Strong Uniqueness.”
Journal of Differential Geometry, vol. 130, International Press, 2025,
pp. 209–68, doi:10.4310/jdg/1747065796.'
short: S. Hensel, T. Laux, Journal of Differential Geometry 130 (2025) 209–268.
corr_author: '1'
date_created: 2021-09-13T12:17:10Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-05-28T09:27:05Z
day: '01'
department:
- _id: JuFi
doi: 10.4310/jdg/1747065796
ec_funded: 1
external_id:
arxiv:
- '2109.04233'
intvolume: ' 130'
keyword:
- Mean curvature flow
- gradient flows
- varifolds
- weak solutions
- weak-strong uniqueness
- calibrated geometry
- gradient-flow calibrations
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2109.04233
month: '05'
oa: 1
oa_version: Preprint
page: 209-268
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
call_identifier: H2020
grant_number: '948819'
name: Bridging Scales in Random Materials
publication: Journal of Differential Geometry
publication_identifier:
eissn:
- 1945-743X
issn:
- 0022-040X
publication_status: published
publisher: International Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A new varifold solution concept for mean curvature flow: Convergence of the
Allen-Cahn equation and weak-strong uniqueness'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 130
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '10045'
abstract:
- lang: eng
text: "Given a fixed finite metric space (V,μ), the {\\em minimum 0-extension problem},
denoted as 0-Ext[μ], is equivalent to the following optimization problem: minimize
function of the form minx∈Vn∑ifi(xi)+∑ijcijμ(xi,xj) where cij,cvi are given nonnegative
costs and fi:V→R are functions given by fi(xi)=∑v∈Vcviμ(xi,v). The computational
complexity of 0-Ext[μ] has been recently established by Karzanov and by Hirai:
if metric μ is {\\em orientable modular} then 0-Ext[μ] can be solved in polynomial
time, otherwise 0-Ext[μ] is NP-hard. To prove the tractability part, Hirai developed
a theory of discrete convex functions on orientable modular graphs generalizing
several known classes of functions in discrete convex analysis, such as L♮-convex
functions. We consider a more general version of the problem in which unary functions
fi(xi) can additionally have terms of the form cuv;iμ(xi,{u,v}) for {u,v}∈F, where
set F⊆(V2) is fixed. We extend the complexity classification above by providing
an explicit condition on (μ,F) for the problem to be tractable. In order to prove
the tractability part, we generalize Hirai's theory and define a larger class
of discrete convex functions. It covers, in particular, another well-known class
of functions, namely submodular functions on an integer lattice. Finally, we improve
the complexity of Hirai's algorithm for solving 0-Ext on orientable modular graphs.\r\n"
acknowledgement: We thank the anonymous reviewers for their careful reading of our
manuscript and their many insightful comments and suggestions. Open access funding
provided by Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Martin
full_name: Dvorak, Martin
id: 40ED02A8-C8B4-11E9-A9C0-453BE6697425
last_name: Dvorak
orcid: 0000-0001-5293-214X
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Dvorak M, Kolmogorov V. Generalized minimum 0-extension problem and discrete
convexity. Mathematical Programming. 2025;209:279-322. doi:10.1007/s10107-024-02064-5
apa: Dvorak, M., & Kolmogorov, V. (2025). Generalized minimum 0-extension problem
and discrete convexity. Mathematical Programming. Springer Nature. https://doi.org/10.1007/s10107-024-02064-5
chicago: Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension
Problem and Discrete Convexity.” Mathematical Programming. Springer Nature,
2025. https://doi.org/10.1007/s10107-024-02064-5.
ieee: M. Dvorak and V. Kolmogorov, “Generalized minimum 0-extension problem and
discrete convexity,” Mathematical Programming, vol. 209. Springer Nature,
pp. 279–322, 2025.
ista: Dvorak M, Kolmogorov V. 2025. Generalized minimum 0-extension problem and
discrete convexity. Mathematical Programming. 209, 279–322.
mla: Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem
and Discrete Convexity.” Mathematical Programming, vol. 209, Springer Nature,
2025, pp. 279–322, doi:10.1007/s10107-024-02064-5.
short: M. Dvorak, V. Kolmogorov, Mathematical Programming 209 (2025) 279–322.
corr_author: '1'
date_created: 2021-09-27T10:48:23Z
date_published: 2025-01-01T00:00:00Z
date_updated: 2025-05-19T13:52:10Z
day: '01'
ddc:
- '004'
department:
- _id: GradSch
- _id: VlKo
doi: 10.1007/s10107-024-02064-5
external_id:
arxiv:
- '2109.10203'
isi:
- '001176563300001'
file:
- access_level: open_access
checksum: 25d9bd490719b45eca84f4d93a06c69f
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creator: dernst
date_created: 2025-04-16T09:36:08Z
date_updated: 2025-04-16T09:36:08Z
file_id: '19578'
file_name: 2025_MathProgramming_Dvorak.pdf
file_size: 839510
relation: main_file
success: 1
file_date_updated: 2025-04-16T09:36:08Z
has_accepted_license: '1'
intvolume: ' 209'
isi: 1
keyword:
- minimum 0-extension problem
- metric labeling problem
- discrete metric spaces
- metric extensions
- computational complexity
- valued constraint satisfaction problems
- discrete convex analysis
- L-convex functions
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 279-322
publication: Mathematical Programming
publication_identifier:
eissn:
- 1436-4646
issn:
- 0025-5610
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Generalized minimum 0-extension problem and discrete convexity
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 209
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '20820'
abstract:
- lang: eng
text: 'The high computational costs of large language models (LLMs) have led to
a flurry of research on LLM compression, via methods such as quantization, sparsification,
or structured pruning. A new frontier in this area is given by dynamic, non-uniform
compression methods, which adjust the compression levels (e.g., sparsity) per-block
or even per-layer in order to minimize accuracy loss, while guaranteeing a global
compression threshold. Yet, current methods rely on estimating the "importance"
of a given layer, implicitly assuming that layers contribute independently to
the overall compression error. We begin from the motivating observation that this
independence assumption does not generally hold for LLM compression: pruning a
model further may even significantly recover performance. To address this, we
propose EvoPress, a novel evolutionary framework for dynamic LLM compression.
By formulating dynamic compression as a general optimization problem, EvoPress
identifies optimal compression profiles in a highly efficient manner, and generalizes
across diverse models and compression techniques. Via EvoPress, we achieve state-of-the-art
performance for dynamic compression of Llama, Mistral, and Phi models, setting
new benchmarks for structural pruning (block/layer dropping), unstructured sparsity,
and quantization with dynamic bitwidths.'
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Oliver
full_name: Sieberling, Oliver
last_name: Sieberling
- first_name: Denis
full_name: Kuznedelev, Denis
last_name: Kuznedelev
- first_name: Eldar
full_name: Kurtic, Eldar
id: 47beb3a5-07b5-11eb-9b87-b108ec578218
last_name: Kurtic
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
citation:
ama: 'Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. EvoPress: Accurate dynamic
model compression via evolutionary search. In: 42nd International Conference
on Machine Learning. Vol 267. ML Research Press; 2025:55556-55590.'
apa: 'Sieberling, O., Kuznedelev, D., Kurtic, E., & Alistarh, D.-A. (2025).
EvoPress: Accurate dynamic model compression via evolutionary search. In 42nd
International Conference on Machine Learning (Vol. 267, pp. 55556–55590).
Vancouver, Canada: ML Research Press.'
chicago: 'Sieberling, Oliver, Denis Kuznedelev, Eldar Kurtic, and Dan-Adrian Alistarh.
“EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” In 42nd
International Conference on Machine Learning, 267:55556–90. ML Research Press,
2025.'
ieee: 'O. Sieberling, D. Kuznedelev, E. Kurtic, and D.-A. Alistarh, “EvoPress: Accurate
dynamic model compression via evolutionary search,” in 42nd International Conference
on Machine Learning, Vancouver, Canada, 2025, vol. 267, pp. 55556–55590.'
ista: 'Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. 2025. EvoPress: Accurate
dynamic model compression via evolutionary search. 42nd International Conference
on Machine Learning. ICML: International Conference on Machine Learning, PMLR,
vol. 267, 55556–55590.'
mla: 'Sieberling, Oliver, et al. “EvoPress: Accurate Dynamic Model Compression via
Evolutionary Search.” 42nd International Conference on Machine Learning,
vol. 267, ML Research Press, 2025, pp. 55556–90.'
short: O. Sieberling, D. Kuznedelev, E. Kurtic, D.-A. Alistarh, in:, 42nd International
Conference on Machine Learning, ML Research Press, 2025, pp. 55556–55590.
conference:
end_date: 2025-07-19
location: Vancouver, Canada
name: 'ICML: International Conference on Machine Learning'
start_date: 2025-07-13
corr_author: '1'
date_created: 2025-12-14T23:02:05Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-12-16T12:34:32Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
arxiv:
- '2410.14649'
file:
- access_level: open_access
checksum: 1d744fbaeb199b08e8b6f48bc0dd047e
content_type: application/pdf
creator: dernst
date_created: 2025-12-16T12:32:40Z
date_updated: 2025-12-16T12:32:40Z
file_id: '20828'
file_name: 2025_ICML_Sieberling.pdf
file_size: 908379
relation: main_file
success: 1
file_date_updated: 2025-12-16T12:32:40Z
has_accepted_license: '1'
intvolume: ' 267'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 55556-55590
publication: 42nd International Conference on Machine Learning
publication_identifier:
eissn:
- 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'EvoPress: Accurate dynamic model compression via evolutionary search'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '20821'
abstract:
- lang: eng
text: Modern deep neural networks exhibit heterogeneity across numerous layers of
various types such as residuals, multi-head attention, etc., due to varying structures
(dimensions, activation functions, etc.), distinct representation characteristics,
which impact predictions. We develop a general layer-wise quantization framework
with tight variance and code-length bounds, adapting to the heterogeneities over
the course of training. We then apply a new layer-wise quantization technique
within distributed variational inequalities (VIs), proposing a novel Quantized
Optimistic Dual Averaging (QODA) algorithm with adaptive learning rates, which
achieves competitive convergence rates for monotone VIs. We empirically show that
QODA achieves up to a 150% speedup over the baselines in end-to-end training time
for training Wasserstein GAN on 12+GPUs.
acknowledgement: "This work was supported by Hasler Foundation Program: Hasler Responsible
AI (project number 21043). The research was also sponsored by the Army Research
Office and was accomplished under Grant Number W911NF-24-1-0048. This work was further
funded by the Swiss National Science Foundation (SNSF) under grant number 200021_205011.
We also acknowledge project A11 of the Swiss National Supercomputing Centre (CSCS)
for providing computing resources. Dan Alistarh and Ilia Markov were supported in
part through the ERC Proofof-Concept grant FastML (Grant Agreement 101158077). Ali
Ramezani-Kebrya was supported by the Research Council of Norway through FRIPRO Grant
under project number 356103, its Centres of Excellence scheme, Integreat - Norwegian
Centre for knowledge-driven machine learning under\r\nproject number 332645 - and
its Centre for Research-based Innovation funding scheme (Visual Intelligence under
grant no. 309439)."
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Anh Duc
full_name: Nguyen, Anh Duc
last_name: Nguyen
- first_name: Ilia
full_name: Markov, Ilia
id: D0CF4148-C985-11E9-8066-0BDEE5697425
last_name: Markov
- first_name: Frank Zhengqing
full_name: Wu, Frank Zhengqing
last_name: Wu
- first_name: Ali
full_name: Ramezani-Kebrya, Ali
last_name: Ramezani-Kebrya
- first_name: Kimon
full_name: Antonakopoulos, Kimon
last_name: Antonakopoulos
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Volkan
full_name: Cevher, Volkan
last_name: Cevher
citation:
ama: 'Nguyen AD, Markov I, Wu FZ, et al. Layer-wise quantization for quantized optimistic
dual averaging. In: 42nd International Conference on Machine Learning.
Vol 267. ML Research Press; 2025:46026-46072.'
apa: 'Nguyen, A. D., Markov, I., Wu, F. Z., Ramezani-Kebrya, A., Antonakopoulos,
K., Alistarh, D.-A., & Cevher, V. (2025). Layer-wise quantization for quantized
optimistic dual averaging. In 42nd International Conference on Machine Learning
(Vol. 267, pp. 46026–46072). Vancouver, Canada: ML Research Press.'
chicago: Nguyen, Anh Duc, Ilia Markov, Frank Zhengqing Wu, Ali Ramezani-Kebrya,
Kimon Antonakopoulos, Dan-Adrian Alistarh, and Volkan Cevher. “Layer-Wise Quantization
for Quantized Optimistic Dual Averaging.” In 42nd International Conference
on Machine Learning, 267:46026–72. ML Research Press, 2025.
ieee: A. D. Nguyen et al., “Layer-wise quantization for quantized optimistic
dual averaging,” in 42nd International Conference on Machine Learning,
Vancouver, Canada, 2025, vol. 267, pp. 46026–46072.
ista: 'Nguyen AD, Markov I, Wu FZ, Ramezani-Kebrya A, Antonakopoulos K, Alistarh
D-A, Cevher V. 2025. Layer-wise quantization for quantized optimistic dual averaging.
42nd International Conference on Machine Learning. ICML: International Conference
on Machine Learning, PMLR, vol. 267, 46026–46072.'
mla: Nguyen, Anh Duc, et al. “Layer-Wise Quantization for Quantized Optimistic Dual
Averaging.” 42nd International Conference on Machine Learning, vol. 267,
ML Research Press, 2025, pp. 46026–72.
short: A.D. Nguyen, I. Markov, F.Z. Wu, A. Ramezani-Kebrya, K. Antonakopoulos, D.-A.
Alistarh, V. Cevher, in:, 42nd International Conference on Machine Learning, ML
Research Press, 2025, pp. 46026–46072.
conference:
end_date: 2025-07-19
location: Vancouver, Canada
name: 'ICML: International Conference on Machine Learning'
start_date: 2025-07-13
date_created: 2025-12-14T23:02:06Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-12-16T12:46:54Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
arxiv:
- '2505.14371'
file:
- access_level: open_access
checksum: a7edf0e4304171a3e035842b3aab1704
content_type: application/pdf
creator: dernst
date_created: 2025-12-16T12:45:41Z
date_updated: 2025-12-16T12:45:41Z
file_id: '20830'
file_name: 2025_ICML_Nguyen.pdf
file_size: 756213
relation: main_file
success: 1
file_date_updated: 2025-12-16T12:45:41Z
has_accepted_license: '1'
intvolume: ' 267'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 46026-46072
project:
- _id: 8e35c14b-16d5-11f0-9cad-a3fc35339161
grant_number: '101158077'
name: 'FastML: Efficient and Cost-Effective Distributed Machine Learning'
publication: 42nd International Conference on Machine Learning
publication_identifier:
eissn:
- 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Layer-wise quantization for quantized optimistic dual averaging
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '20839'
abstract:
- lang: eng
text: For every couple of Hausdorff functions ψ and φ verifying some mild assumptions,
there exists a compact subset K of the Baire space such that the φ-Hausdorff measure
and the ψ-packing measure on K are both finite and positive. Such examples are
then embedded in any infinite dimensional Banach space to answer positively a
question of Fan on the existence of metric spaces with arbitrary scales.
article_processing_charge: Yes
article_type: original
author:
- first_name: Mathieu
full_name: Helfter, Mathieu
id: 7d296fbe-e2c6-11ee-84d3-d5c2945f9a57
last_name: Helfter
citation:
ama: Helfter M. Sets with arbitrary Hausdorff and packing scales in infinite dimensional
Banach spaces. Journal of Fractal Geometry. 2025. doi:10.4171/jfg/177
apa: Helfter, M. (2025). Sets with arbitrary Hausdorff and packing scales in infinite
dimensional Banach spaces. Journal of Fractal Geometry. EMS Press. https://doi.org/10.4171/jfg/177
chicago: Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in
Infinite Dimensional Banach Spaces.” Journal of Fractal Geometry. EMS Press,
2025. https://doi.org/10.4171/jfg/177.
ieee: M. Helfter, “Sets with arbitrary Hausdorff and packing scales in infinite
dimensional Banach spaces,” Journal of Fractal Geometry. EMS Press, 2025.
ista: Helfter M. 2025. Sets with arbitrary Hausdorff and packing scales in infinite
dimensional Banach spaces. Journal of Fractal Geometry.
mla: Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite
Dimensional Banach Spaces.” Journal of Fractal Geometry, EMS Press, 2025,
doi:10.4171/jfg/177.
short: M. Helfter, Journal of Fractal Geometry (2025).
corr_author: '1'
date_created: 2025-12-19T10:15:37Z
date_published: 2025-11-07T00:00:00Z
date_updated: 2026-02-16T11:44:20Z
day: '07'
department:
- _id: VaKa
doi: 10.4171/jfg/177
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.4171/jfg/177
month: '11'
oa: 1
oa_version: Published Version
publication: Journal of Fractal Geometry
publication_identifier:
eissn:
- 2308-1317
issn:
- 2308-1309
publication_status: epub_ahead
publisher: EMS Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach
spaces
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20844'
abstract:
- lang: eng
text: "We introduce and construct a new proof system called Non-interactive Arguments
of Knowledge or Space (NArKoS), where a space-bounded prover can convince a verifier
they know a secret, while having access to sufficient space allows one to forge
indistinguishable proofs without the secret.\r\nAn application of NArKoS are space-deniable
proofs, which are proofs of knowledge (say for authentication in access control)
that are sound when executed by a lightweight device like a smart-card or an RFID
chip that cannot have much storage, but are deniable (in the strong sense of online
deniability) as the verifier, like a card reader, can efficiently forge such proofs.\r\nWe
construct NArKoS in the random oracle model using an OR-proof combining a sigma
protocol (for the proof of knowledge of the secret) with a new proof system called
simulatable Proof of Transient Space (simPoTS). We give two different constructions
of simPoTS, one based on labelling graphs with high pebbling complexity, a technique
used in the construction of memory-hard functions and proofs of space, and a more
practical construction based on the verifiable space-hard functions from TCC’24
where a prover must compute a root of a sparse polynomial. In both cases, the
main challenge is making the proofs efficiently simulatable."
acknowledgement: "Jesko Dujmovic: Funded by the European Union (ERC, LACONIC, 101041207).
Views and opinions expressed are however those of the author(s) only and do not
necessarily reflect those of the European Union or the European Research Council.
Neither the European Union nor the granting authority can be held responsible for
them.\r\nChristoph U. Günther and Krzysztof Pietrzak: This research was funded in
whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access
purposes, the author has applied a CC BY public copyright license to any author-accepted
manuscript version arising from this submission."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Jesko
full_name: Dujmovic, Jesko
last_name: Dujmovic
- first_name: Christoph Ullrich
full_name: Günther, Christoph Ullrich
id: ec98511c-eb8e-11eb-b029-edd25d7271a1
last_name: Günther
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Dujmovic J, Günther CU, Pietrzak KZ. Space-deniable proofs. In: 23rd International
Conference on Theory of Cryptography. Vol 16271. Springer Nature; 2025:171-202.
doi:10.1007/978-3-032-12290-2_6'
apa: 'Dujmovic, J., Günther, C. U., & Pietrzak, K. Z. (2025). Space-deniable
proofs. In 23rd International Conference on Theory of Cryptography (Vol.
16271, pp. 171–202). Aarhus, Denmark: Springer Nature. https://doi.org/10.1007/978-3-032-12290-2_6'
chicago: Dujmovic, Jesko, Christoph Ullrich Günther, and Krzysztof Z Pietrzak. “Space-Deniable
Proofs.” In 23rd International Conference on Theory of Cryptography, 16271:171–202.
Springer Nature, 2025. https://doi.org/10.1007/978-3-032-12290-2_6.
ieee: J. Dujmovic, C. U. Günther, and K. Z. Pietrzak, “Space-deniable proofs,” in
23rd International Conference on Theory of Cryptography, Aarhus, Denmark,
2025, vol. 16271, pp. 171–202.
ista: 'Dujmovic J, Günther CU, Pietrzak KZ. 2025. Space-deniable proofs. 23rd International
Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol.
16271, 171–202.'
mla: Dujmovic, Jesko, et al. “Space-Deniable Proofs.” 23rd International Conference
on Theory of Cryptography, vol. 16271, Springer Nature, 2025, pp. 171–202,
doi:10.1007/978-3-032-12290-2_6.
short: J. Dujmovic, C.U. Günther, K.Z. Pietrzak, in:, 23rd International Conference
on Theory of Cryptography, Springer Nature, 2025, pp. 171–202.
conference:
end_date: 2025-12-05
location: Aarhus, Denmark
name: 'TCC: Theory of Cryptography'
start_date: 2025-12-01
corr_author: '1'
date_created: 2025-12-21T23:01:33Z
date_published: 2025-12-05T00:00:00Z
date_updated: 2025-12-29T11:44:16Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-032-12290-2_6
intvolume: ' 16271'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2025/1723
month: '12'
oa: 1
oa_version: Preprint
page: 171-202
project:
- _id: 34a34d57-11ca-11ed-8bc3-a2688a8724e1
grant_number: F8509
name: Security and Privacy by Design for Complex Systems
publication: 23rd International Conference on Theory of Cryptography
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783032122896'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Space-deniable proofs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16271
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20845'
abstract:
- lang: eng
text: "We develop new attacks against the Evasive LWE family of assumptions, in
both the public and private-coin regime. To the best of our knowledge, ours are
the first attacks against Evasive LWE in the public-coin regime, for any instantiation
from the family. Our attacks are summarized below.\r\n\r\nPublic-Coin Attacks.\r\n1.The
recent work by Hseih, Lin and Luo [17] constructed the first Attribute Based Encryption
(ABE) for unbounded depth circuits by relying on the “circular” evasive LWE assumption.
This assumption has been popularly considered as a safe, public-coin instance
of Evasive LWE in contrast to its “private-coin” cousins (for instance, see [10,
11]).\r\nWe provide the first attack against this assumption, challenging the
widely held belief that this is a public-coin assumption.\r\n2. We demonstrate
a counter-example against vanilla public-coin evasive LWE by Wee [26] in an unnatural
parameter regime. Our attack crucially relies on the error in the pre-condition
being larger than the error in the post-condition, necessitating a refinement
of the assumption.\r\n\r\nPrivate-Coin Attacks.\r\n1. The recent work by Agrawal,
Kumari and Yamada [2] constructed the first functional encryption scheme for pseudorandom
functionalities (PRFE) and extended this to obfuscation for pseudorandom functionalities
(PRIO) [4] by relying on private-coin evasive LWE. We provide a new attack against
the assumption stated in the first posting of their work (subsequently refined
to avoid these attacks).\r\n2. The recent work by Branco et al. [8] (concurrently
to [4]) provides a construction of obfuscation for pseudorandom functionalities
by relying on private-coin evasive LWE. We provide a new attack against their
stated assumption.\r\n3. Branco et al. [8] showed that there exist contrived,
“self-referential” classes of pseudorandom functionalities for which pseudorandom
obfuscation cannot exist. We extend their techniques to develop an analogous result
for pseudorandom functional encryption.\r\n\r\nWhile Evasive LWE was developed
to specifically avoid “zeroizing attacks”, our work shows that in certain settings,
such attacks can still apply."
acknowledgement: "We thank Rachel Lin for expressing concern about the applicability
of “HJL-style” attacks [15] on the construction in [2] during a talk by the first
author about [2]. This was the starting point of the investigation that led us to
develop the attack in [5, Sec 4.1]. The first author also thanks Hoeteck Wee for
sharing his rationale for introducing evasive LWE.\r\nThe first author is supported
by the CyStar center of excellence, the VHAR faculty chair, and the C3iHub fellowship.
The third author thanks Cystar, IIT Madras, for supporting a visit to IIT Madras
during which the collaboration was initiated. The 4th author is partly supported
by JST CREST Grant Number JPMJCR22M1."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Shweta
full_name: Agrawal, Shweta
last_name: Agrawal
- first_name: Anuja
full_name: Modi, Anuja
last_name: Modi
- first_name: Anshu
full_name: Yadav, Anshu
id: dc8f1524-403e-11ee-bf07-9649ad996e21
last_name: Yadav
- first_name: Shota
full_name: Yamada, Shota
last_name: Yamada
citation:
ama: 'Agrawal S, Modi A, Yadav A, Yamada S. Zeroizing attacks against evasive and circular
evasive LWE. In: 23rd International Conference on Theory of Cryptography.
Vol 16269. Springer Nature; 2025:259-290. doi:10.1007/978-3-032-12293-3_9'
apa: 'Agrawal, S., Modi, A., Yadav, A., & Yamada, S. (2025). Zeroizing attacks
against evasive and circular evasive LWE. In 23rd International Conference
on Theory of Cryptography (Vol. 16269, pp. 259–290). Aarhus, Denmark: Springer
Nature. https://doi.org/10.1007/978-3-032-12293-3_9'
chicago: Agrawal, Shweta, Anuja Modi, Anshu Yadav, and Shota Yamada. “Zeroizing
Attacks against Evasive and Circular Evasive LWE.” In 23rd International Conference
on Theory of Cryptography, 16269:259–90. Springer Nature, 2025. https://doi.org/10.1007/978-3-032-12293-3_9.
ieee: S. Agrawal, A. Modi, A. Yadav, and S. Yamada, “Zeroizing attacks against evasive
and circular evasive LWE,” in 23rd International Conference on Theory of Cryptography,
Aarhus, Denmark, 2025, vol. 16269, pp. 259–290.
ista: 'Agrawal S, Modi A, Yadav A, Yamada S. 2025. Zeroizing attacks against evasive
and circular evasive LWE. 23rd International Conference on Theory of Cryptography.
TCC: Theory of Cryptography, LNCS, vol. 16269, 259–290.'
mla: Agrawal, Shweta, et al. “Zeroizing Attacks against Evasive and Circular Evasive
LWE.” 23rd International Conference on Theory of Cryptography, vol. 16269,
Springer Nature, 2025, pp. 259–90, doi:10.1007/978-3-032-12293-3_9.
short: S. Agrawal, A. Modi, A. Yadav, S. Yamada, in:, 23rd International Conference
on Theory of Cryptography, Springer Nature, 2025, pp. 259–290.
conference:
end_date: 2025-12-05
location: Aarhus, Denmark
name: 'TCC: Theory of Cryptography'
start_date: 2025-12-01
date_created: 2025-12-21T23:01:33Z
date_published: 2025-12-05T00:00:00Z
date_updated: 2025-12-29T11:51:13Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-032-12293-3_9
intvolume: ' 16269'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2025/375
month: '12'
oa: 1
oa_version: Preprint
page: 259-290
publication: 23rd International Conference on Theory of Cryptography
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783032122926'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Zeroizing attacks against evasive and circular evasive LWE
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16269
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20846'
abstract:
- lang: eng
text: "CVRFs are PRFs that unify the properties of verifiable and constrained PRFs.
Since they were introduced concurrently by Fuchsbauer and Chandran-Raghuraman-Vinayagamurthy
in 2014, it has been an open problem to construct CVRFs without using heavy machinery
such as multilinear maps, obfuscation or functional encryption.\r\nWe solve this
problem by constructing a prefix-constrained verifiable PRF that does not rely
on the aforementioned assumptions. Essentially, our construction is a verifiable
version of the Goldreich-Goldwasser-Micali PRF. To achieve verifiability we leverage
degree-2 algebraic PRGs and bilinear groups. In short, proofs consist of intermediate
values of the Goldreich-Goldwasser-Micali PRF raised to the exponents of group
elements. These outputs can be verified using pairings since the underlying PRG
is of degree 2.\r\nWe prove the selective security of our construction under the
Decisional Square Diffie-Hellman (DSDH) assumption and a new assumption, which
we dub recursive Decisional Diffie-Hellman (recursive DDH).\r\nWe prove the soundness
of recursive DDH in the generic group model assuming the hardness of the Multivariate
Quadratic (MQ) problem and a new variant thereof, which we call MQ+.\r\nLast,
in terms of applications, we observe that our CVRF is also an exponent (C)VRF
in the plain model. Exponent VRFs were recently introduced by Boneh et al. (Eurocrypt’25)
with various applications to threshold cryptography in mind. In addition to that,
we give further applications for prefix-CVRFs in the blockchain setting, namely,
stake-pooling and compressible randomness beacons."
acknowledgement: "We thank Jonas Steinbach and Gertjan De Mulder for helpful discussions
on BIP 32, Dennis Hofheinz and Julia Kastner for helpful discussions on early prototypes
of our CVRF, and Klaus Kraßnitzer for running pairing benchmarks on his MacBook
Pro.\r\nChristoph U. Günther: This research was funded in whole or in part by the
Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has
applied a CC BY public copyright license to any author-accepted manuscript version
arising from this submission."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Nicholas
full_name: Brandt, Nicholas
last_name: Brandt
- first_name: Miguel
full_name: Cueto Noval, Miguel
id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc
last_name: Cueto Noval
orcid: 0000-0002-2505-4246
- first_name: Christoph Ullrich
full_name: Günther, Christoph Ullrich
id: ec98511c-eb8e-11eb-b029-edd25d7271a1
last_name: Günther
- first_name: Akin
full_name: Ünal, Akin
id: f6b56fb6-dc63-11ee-9dbf-f6780863a85a
last_name: Ünal
orcid: 0000-0002-8929-0221
- first_name: Stella
full_name: Wohnig, Stella
last_name: Wohnig
citation:
ama: 'Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. Constrained verifiable
random functions without obfuscation and friends. In: 23rd International Conference
on Theory of Cryptography. Vol 16271. Springer Nature; 2025:478-511. doi:10.1007/978-3-032-12290-2_16'
apa: 'Brandt, N., Cueto Noval, M., Günther, C. U., Ünal, A., & Wohnig, S. (2025).
Constrained verifiable random functions without obfuscation and friends. In 23rd
International Conference on Theory of Cryptography (Vol. 16271, pp. 478–511).
Aarhus, Denmark: Springer Nature. https://doi.org/10.1007/978-3-032-12290-2_16'
chicago: Brandt, Nicholas, Miguel Cueto Noval, Christoph Ullrich Günther, Akin Ünal,
and Stella Wohnig. “Constrained Verifiable Random Functions without Obfuscation
and Friends.” In 23rd International Conference on Theory of Cryptography,
16271:478–511. Springer Nature, 2025. https://doi.org/10.1007/978-3-032-12290-2_16.
ieee: N. Brandt, M. Cueto Noval, C. U. Günther, A. Ünal, and S. Wohnig, “Constrained
verifiable random functions without obfuscation and friends,” in 23rd International
Conference on Theory of Cryptography, Aarhus, Denmark, 2025, vol. 16271, pp.
478–511.
ista: 'Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. 2025. Constrained
verifiable random functions without obfuscation and friends. 23rd International
Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol.
16271, 478–511.'
mla: Brandt, Nicholas, et al. “Constrained Verifiable Random Functions without Obfuscation
and Friends.” 23rd International Conference on Theory of Cryptography,
vol. 16271, Springer Nature, 2025, pp. 478–511, doi:10.1007/978-3-032-12290-2_16.
short: N. Brandt, M. Cueto Noval, C.U. Günther, A. Ünal, S. Wohnig, in:, 23rd International
Conference on Theory of Cryptography, Springer Nature, 2025, pp. 478–511.
conference:
end_date: 2025-12-05
location: Aarhus, Denmark
name: 'TCC: Theory of Cryptography'
start_date: 2025-12-01
corr_author: '1'
date_created: 2025-12-21T23:01:34Z
date_published: 2025-12-05T00:00:00Z
date_updated: 2025-12-29T11:11:29Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-032-12290-2_16
intvolume: ' 16271'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2025/1045
month: '12'
oa: 1
oa_version: Preprint
page: 478-511
project:
- _id: 34a34d57-11ca-11ed-8bc3-a2688a8724e1
grant_number: F8509
name: Security and Privacy by Design for Complex Systems
publication: 23rd International Conference on Theory of Cryptography
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783032122896'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Constrained verifiable random functions without obfuscation and friends
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16271
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20847'
abstract:
- lang: eng
text: "We report on an experimental active matter system with motion restricted
to four cardinal directions. Our particles are magnetite-doped colloidal spheres
driven by the Quincke electrorotational instability. The absence of a magnetic
field (|\U0001D469|=0) leads to circular trajectories interspersed with short
spontaneous runs. Intermediate fields (|\U0001D469|≲20mT) linearize the motion
along the axis perpendicular to \U0001D469. At high magnetic fields, we observe
the surprising emergence of a second, distinct linearization along the axis parallel
to \U0001D469. With numerical simulations, we show that this behavior can be explained
by anisotropic magnetic susceptibility."
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: ScienComp
- _id: LifeSc
acknowledgement: "This research was funded in whole or in part by the Austrian Science
Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from
the European Research Council (ERC) under the European Union’s Horizon 2020 research
and innovation programme (Grant\r\nAgreement No. 949120). This research was supported
by the Scientific Service Units of The Institute of Science and Technology Austria
(ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility,
Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge
the crucial contributions of Alexandre Morin in getting the project off the ground,
and Jack Merrin for creating the SU-8 deposition protocol used in the construction
of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their
work on single-particle characterization. "
article_number: '065418'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Eavan
full_name: Fitzgerald, Eavan
id: 2df8ab8f-080d-11ed-979a-bfe651ca3afa
last_name: Fitzgerald
- first_name: Cécile
full_name: Clavaud, Cécile
id: 5f654c5d-04a1-11eb-ab36-ba9ffec58bd8
last_name: Clavaud
orcid: 0000-0002-1843-3803
- first_name: Debasish
full_name: Das, Debasish
last_name: Das
- first_name: Isaac C
full_name: Lenton, Isaac C
id: a550210f-223c-11ec-8182-e2d45e817efb
last_name: Lenton
orcid: 0000-0002-5010-6984
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
citation:
ama: 'Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right
angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical
Review E. 2025;112(6). doi:10.1103/1ss8-31rb'
apa: 'Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., & Waitukaitis, S.
R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic
active matter. Physical Review E. American Physical Society. https://doi.org/10.1103/1ss8-31rb'
chicago: 'Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott
R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic
Active Matter.” Physical Review E. American Physical Society, 2025. https://doi.org/10.1103/1ss8-31rb.'
ieee: 'E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling
at right angles: Magnetic anisotropy enables dual-anisotropic active matter,”
Physical Review E, vol. 112, no. 6. American Physical Society, 2025.'
ista: 'Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling
at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical
Review E. 112(6), 065418.'
mla: 'Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables
Dual-Anisotropic Active Matter.” Physical Review E, vol. 112, no. 6, 065418,
American Physical Society, 2025, doi:10.1103/1ss8-31rb.'
short: E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical
Review E 112 (2025).
corr_author: '1'
date_created: 2025-12-21T23:01:34Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2025-12-29T11:19:34Z
day: '01'
ddc:
- '530'
department:
- _id: ScWa
doi: 10.1103/1ss8-31rb
ec_funded: 1
external_id:
arxiv:
- '2508.05643'
file:
- access_level: open_access
checksum: d593e933f976c3f3cde37ad66539d57d
content_type: application/pdf
creator: dernst
date_created: 2025-12-29T11:15:42Z
date_updated: 2025-12-29T11:15:42Z
file_id: '20862'
file_name: 2025_PhysReviewE_Fitzgerald.pdf
file_size: 2131491
relation: main_file
success: 1
file_date_updated: 2025-12-29T11:15:42Z
has_accepted_license: '1'
intvolume: ' 112'
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: bd8eede5-d553-11ed-ba76-eaded0d13485
grant_number: E 298
name: 'MixQUIckR: Mixing with QUIncke Rollers'
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
call_identifier: H2020
grant_number: '949120'
name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
publication: Physical Review E
publication_identifier:
eissn:
- 2470-0053
issn:
- 2470-0045
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active
matter'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20848'
abstract:
- lang: eng
text: 'Genetic variation that influences complex disease susceptibility is introduced
into the population by mutation and removed by natural selection and genetic drift.
This mutation–selection–drift balance (MSDB) shapes the prevalence of a disease
and its genetic architecture. To date, however, MSDB has been modeled only for
monogenic (Mendelian) diseases. Here, we develop an MSDB model for complex disease
susceptibility: we assume that genotype relates to disease risk according to the
canonical liability threshold model and that the selection on variants affecting
risk stems from the fitness cost of the disease. We focus on diseases that are
highly polygenic, entail a substantial fitness cost, and are neither extremely
common in the population nor exceedingly rare. The comparison of model predictions
with genome-wide association studies and other observations in humans indicates
that common genetic variation affecting complex disease susceptibility is little
affected by directional selection and instead shaped by pleiotropic stabilizing
selection on other traits. In turn, directional selection may exert a more substantial
effect on rare, large-effect variants. Our results also suggest that current estimates
of disease heritability are likely biased. The model thus provides a better understanding
of the evolutionary processes that shape the architecture and prevalence of complex
diseases.'
acknowledgement: We thank Nick Barton, Magnus Nordborg, John Novembre, Molly Przeworski,
and Himani Sachdeva for many helpful discussions and for comments on the manuscript,
and we thank Joshua Schraiber and 2 anonymous reviewers for comments on the manuscript.
We also thank members of the Sella, Przeworski and Andolfatto labs at Columbia University,
and the Berg, Novembre and Steinrücken labs at the University of Chicago, for feedback
on the work at various stages. This work was completed in part with resources provided
by the University of Chicago's Research Computing Center. This work was supported
by National Institutes of Health F32 grant GM126787 and R35 grant GM151257 to J.J.B.
and National Institutes of Health R01 grant GM115889 to G.S.
article_number: iyaf220
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jeremy J.
full_name: Berg, Jeremy J.
last_name: Berg
- first_name: Xinyi
full_name: Li, Xinyi
last_name: Li
- first_name: Kellen
full_name: Riall, Kellen
last_name: Riall
- first_name: Laura
full_name: Hayward, Laura
id: fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b
last_name: Hayward
- first_name: Guy
full_name: Sella, Guy
last_name: Sella
citation:
ama: Berg JJ, Li X, Riall K, Hayward L, Sella G. Mutation–selection–drift balance
models of complex diseases. Genetics. 2025;231(4). doi:10.1093/genetics/iyaf220
apa: Berg, J. J., Li, X., Riall, K., Hayward, L., & Sella, G. (2025). Mutation–selection–drift
balance models of complex diseases. Genetics. Oxford University Press.
https://doi.org/10.1093/genetics/iyaf220
chicago: Berg, Jeremy J., Xinyi Li, Kellen Riall, Laura Hayward, and Guy Sella.
“Mutation–Selection–Drift Balance Models of Complex Diseases.” Genetics.
Oxford University Press, 2025. https://doi.org/10.1093/genetics/iyaf220.
ieee: J. J. Berg, X. Li, K. Riall, L. Hayward, and G. Sella, “Mutation–selection–drift
balance models of complex diseases,” Genetics, vol. 231, no. 4. Oxford
University Press, 2025.
ista: Berg JJ, Li X, Riall K, Hayward L, Sella G. 2025. Mutation–selection–drift
balance models of complex diseases. Genetics. 231(4), iyaf220.
mla: Berg, Jeremy J., et al. “Mutation–Selection–Drift Balance Models of Complex
Diseases.” Genetics, vol. 231, no. 4, iyaf220, Oxford University Press,
2025, doi:10.1093/genetics/iyaf220.
short: J.J. Berg, X. Li, K. Riall, L. Hayward, G. Sella, Genetics 231 (2025).
date_created: 2025-12-21T23:01:34Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2025-12-29T11:29:16Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1093/genetics/iyaf220
external_id:
pmid:
- '41073879'
file:
- access_level: open_access
checksum: b02eb6b78028b8bef435edc8435a8468
content_type: application/pdf
creator: dernst
date_created: 2025-12-29T11:27:51Z
date_updated: 2025-12-29T11:27:51Z
file_id: '20863'
file_name: 2025_Genetics_Berg.pdf
file_size: 1182339
relation: main_file
success: 1
file_date_updated: 2025-12-29T11:27:51Z
has_accepted_license: '1'
intvolume: ' 231'
issue: '4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genetics
publication_identifier:
eissn:
- 1943-2631
issn:
- 0016-6731
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mutation–selection–drift balance models of complex diseases
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 231
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20850'
abstract:
- lang: eng
text: We provide an estimate for the number of nontrivial integer points on the
Pellian surface t^2 - du^2 = 1 in a bounded region. We give a lower bound on the
size of fundamental solutions for almost all d in a certain class, based on a
recent conjecture of Browning and Wilsch about integer points on log K3 surfaces.
We also obtain an upper bound on the average of class number in this class, assuming
the same conjecture.
- lang: fre
text: "Nous donnons une estimation du nombre de points entiers non triviaux sur
la surface pellienne \r\nt^2 - du^2 = 1 dans une région bornée. Nous établissons
une borne inférieure pour la taille des solutions fondamentales pour presque tout
d appartenant à une certaine classe, en nous fondant sur une conjecture récente
de Browning et Wilsch concernant les points entiers sur les surfaces log K3. Nous
obtenons également une borne supérieure pour la moyenne du nombre de classes dans
cette classe, sous la même hypothèse conjecturale."
acknowledgement: The author would like to thank his supervisor Tim Browning for suggesting
this project and many helpful conversations and useful comments. Moreover, he is
grateful to Jakob Glas, Damaris Schindler, Igor Shparlinski, Matteo Verzobio, Victor
Wang, Florian Wilsch and Shuntaro Yamagishi for taking their time to answer his
questions and their valuable suggestions.
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Yijie
full_name: Diao, Yijie
id: 7b7eb4ca-eb2c-11ec-b98b-accec0b20c3b
last_name: Diao
orcid: 0000-0002-4989-5330
citation:
ama: Diao Y. Class numbers and integer points on some Pellian surfaces. Journal
de theorie des nombres de Bordeaux. 2025;37(3):973-988. doi:10.5802/jtnb.1348
apa: Diao, Y. (2025). Class numbers and integer points on some Pellian surfaces.
Journal de Theorie Des Nombres de Bordeaux. Université de Bordeaux. https://doi.org/10.5802/jtnb.1348
chicago: Diao, Yijie. “Class Numbers and Integer Points on Some Pellian Surfaces.”
Journal de Theorie Des Nombres de Bordeaux. Université de Bordeaux, 2025.
https://doi.org/10.5802/jtnb.1348.
ieee: Y. Diao, “Class numbers and integer points on some Pellian surfaces,” Journal
de theorie des nombres de Bordeaux, vol. 37, no. 3. Université de Bordeaux,
pp. 973–988, 2025.
ista: Diao Y. 2025. Class numbers and integer points on some Pellian surfaces. Journal
de theorie des nombres de Bordeaux. 37(3), 973–988.
mla: Diao, Yijie. “Class Numbers and Integer Points on Some Pellian Surfaces.” Journal
de Theorie Des Nombres de Bordeaux, vol. 37, no. 3, Université de Bordeaux,
2025, pp. 973–88, doi:10.5802/jtnb.1348.
short: Y. Diao, Journal de Theorie Des Nombres de Bordeaux 37 (2025) 973–988.
corr_author: '1'
date_created: 2025-12-21T23:01:35Z
date_published: 2025-11-27T00:00:00Z
date_updated: 2025-12-29T10:08:46Z
day: '27'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.5802/jtnb.1348
external_id:
arxiv:
- '2408.03774'
file:
- access_level: open_access
checksum: 67aa0afbc0b5bcbff5341f4d25e6ba20
content_type: application/pdf
creator: dernst
date_created: 2025-12-29T10:05:22Z
date_updated: 2025-12-29T10:05:22Z
file_id: '20861'
file_name: 2025_JTNB_Diao.pdf
file_size: 766196
relation: main_file
success: 1
file_date_updated: 2025-12-29T10:05:22Z
has_accepted_license: '1'
intvolume: ' 37'
issue: '3'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 973-988
publication: Journal de theorie des nombres de Bordeaux
publication_identifier:
eissn:
- 2118-8572
issn:
- 1246-7405
publication_status: published
publisher: Université de Bordeaux
quality_controlled: '1'
scopus_import: '1'
status: public
title: Class numbers and integer points on some Pellian surfaces
tmp:
image: /image/cc_by_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
short: CC BY-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20851'
abstract:
- lang: eng
text: High-voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material
for high power density in lithium-ion batteries. However, it suffers from poor
cycle life associated with the rock-salt phase transformation. This study presents
a straightforward synthesis approach to enhance the electrochemical performance
of LiNi0.5Mn1.5O4 through a synergistic solid-state modification with LiF and
AlF3. This dual modification promotes rapid Li⁺ diffusion, enables near-complete
delithiation/lithiation, approaching the theoretical capacity of disordered LiNi0.5Mn1.5O4,
and, more importantly, effectively mitigates the formation of the rock-salt phase,
thereby enhancing structural stability, as confirmed by operando X-ray absorption
spectroscopy (XAS) and synchrotron X-ray diffraction (SXRD). As a result, the
optimized LiNi0.5Mn1.5O4 (10 mg AlF3 + 30 mg LiF) delivers high reversible capacities
of 142.1, 139.1, 129.2, 121.6, 110.3, 93.5, and 76.1 mAh∙g−1 at 0.2C, 0.5C, 1.0C,
2.0C, 3.0C, 4.0C, and 5.0C, respectively. Full cells using graphite as the anode
and a high-loading cathode exhibit excellent cycling performance. They retain
80% of their capacity after 200 cycles at 0.5C within a voltage window of 3.5–4.9
V with cathode loading of 11 mg∙cm−2. The findings of this study will significantly
advance high-power LiNi0.5Mn1.5O4 materials, offering improved battery life and
thereby enhancing their potential for practical applications.
acknowledged_ssus:
- _id: EM-Fac
- _id: NanoFab
acknowledgement: 'This work was supported by the European Commission-financed project
IntelLigent (HORIZON-CL5-2021-D2-01-02) with project ID number 101069765. In collaboration
with ALBA staff, the operando SXRD and XAS experiments were performed at BL-16-NOTOS
beamline at ALBA Synchrotron Light Source (experiment number: 2023097765). This
research was supported by the Scientific Service Units (SSU) of the Institute of
Science and Technology Austria (ISTA) through resources provided by the Electron
Microscopy Facility (EMF) and the Nanofabrication Facility (NFF), and M.I. and S.H.
acknowledge financial support from ISTA and the Werner Siemens Foundation. Jordi
Jacas Biendicho acknowledges the fellowship RYC2021-034994-I, funded by MICIU/AEI/10.13039/501100011033
and the European Union «NextGenerationEU»/PRTR». Jordi Llorca is a Serra Húnter
Fellow and is grateful to projects MICIN/AEI/FEDER PID2021-124572OB-C31 and Maria
de Maeztu Units of Excellence Programme CEX2023-001300-M, and GC 2021 SGR 01061.'
article_number: e15962
article_processing_charge: Yes
article_type: original
author:
- first_name: Xingqi
full_name: Chang, Xingqi
last_name: Chang
- first_name: Carlos
full_name: Escudero, Carlos
last_name: Escudero
- first_name: Ashley P.
full_name: Black, Ashley P.
last_name: Black
- first_name: Sharona
full_name: Horta, Sharona
id: 03a7e858-01b1-11ec-8b71-99ae6c4a05bc
last_name: Horta
- first_name: Elías
full_name: Martínez, Elías
last_name: Martínez
- first_name: Xuan
full_name: Lu, Xuan
last_name: Lu
- first_name: Jordi
full_name: Llorca, Jordi
last_name: Llorca
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Jordi Jacas
full_name: Biendicho, Jordi Jacas
last_name: Biendicho
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: Chang X, Escudero C, Black AP, et al. Mitigating the rock-salt phase transformation
in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced
Science. 2025. doi:10.1002/advs.202515962
apa: Chang, X., Escudero, C., Black, A. P., Horta, S., Martínez, E., Lu, X., … Cabot,
A. (2025). Mitigating the rock-salt phase transformation in disordered LNMO through
synergetic solid-state AlF3/LiF modifications. Advanced Science. Wiley.
https://doi.org/10.1002/advs.202515962
chicago: Chang, Xingqi, Carlos Escudero, Ashley P. Black, Sharona Horta, Elías Martínez,
Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, and Andreu Cabot.
“Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic
Solid-State AlF3/LiF Modifications.” Advanced Science. Wiley, 2025. https://doi.org/10.1002/advs.202515962.
ieee: X. Chang et al., “Mitigating the rock-salt phase transformation in
disordered LNMO through synergetic solid-state AlF3/LiF modifications,” Advanced
Science. Wiley, 2025.
ista: Chang X, Escudero C, Black AP, Horta S, Martínez E, Lu X, Llorca J, Ibáñez
M, Biendicho JJ, Cabot A. 2025. Mitigating the rock-salt phase transformation
in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced
Science., e15962.
mla: Chang, Xingqi, et al. “Mitigating the Rock-Salt Phase Transformation in Disordered
LNMO through Synergetic Solid-State AlF3/LiF Modifications.” Advanced Science,
e15962, Wiley, 2025, doi:10.1002/advs.202515962.
short: X. Chang, C. Escudero, A.P. Black, S. Horta, E. Martínez, X. Lu, J. Llorca,
M. Ibáñez, J.J. Biendicho, A. Cabot, Advanced Science (2025).
date_created: 2025-12-21T23:01:35Z
date_published: 2025-12-12T00:00:00Z
date_updated: 2025-12-29T10:15:43Z
day: '12'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1002/advs.202515962
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa_version: Published Version
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication: Advanced Science
publication_identifier:
eissn:
- 2198-3844
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mitigating the rock-salt phase transformation in disordered LNMO through synergetic
solid-state AlF3/LiF modifications
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20857'
abstract:
- lang: eng
text: 'Evolutionary games provide a flexible mathematical framework for many problems
in biology and social evolution. Prisoners’ dilemma, and in particular, the important
special case of donation games, represents social dilemmas where cooperation is
mutually beneficial, yet defection is preferred by selfish agents. In evolutionary
games on networks, the agents interact over a population structure. The existence
of population structures that promote cooperative behavior is a fascinating and
active research topic. Previous research establishes structures promoting cooperation
in the limit of weak selection where the benefit-to-cost ratio β exceeds 1.5.
The existence of such structures for medium and strong selection for 1 < ß < 2
and for weak selection for 1 < ß < 1.5 has been a long-standing open question.
First, we answer the open questions in the affirmative: For every selection strength
and every ß > 1, we construct networks promoting cooperation. Second, we present
a robustness result with respect to β and selection strength: Our structures promote
cooperation for a range of these parameter values rather than specific parameter
values. Finally, we supplement our theoretical results with simulation results
on small population structures that show the effectiveness of our construction
over well-studied population structures.'
acknowledgement: J.S. and K.C. were supported by the European Research Council CoG
863818 (ForM-SMArt) and Austrian Science Fund (FWF) 10.55776/COE12.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jakub
full_name: Svoboda, Jakub
id: 130759D2-D7DD-11E9-87D2-DE0DE6697425
last_name: Svoboda
orcid: 0000-0002-1419-3267
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Svoboda J, Chatterjee K. Promoters of cooperation in evolutionary games. Proceedings
of the National Academy of Sciences. 2025;122(51):e2524109122. doi:10.1073/pnas.2524109122
apa: Svoboda, J., & Chatterjee, K. (2025). Promoters of cooperation in evolutionary
games. Proceedings of the National Academy of Sciences. National Academy
of Sciences. https://doi.org/10.1073/pnas.2524109122
chicago: Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in
Evolutionary Games.” Proceedings of the National Academy of Sciences. National
Academy of Sciences, 2025. https://doi.org/10.1073/pnas.2524109122.
ieee: J. Svoboda and K. Chatterjee, “Promoters of cooperation in evolutionary games,”
Proceedings of the National Academy of Sciences, vol. 122, no. 51. National
Academy of Sciences, p. e2524109122, 2025.
ista: Svoboda J, Chatterjee K. 2025. Promoters of cooperation in evolutionary games.
Proceedings of the National Academy of Sciences. 122(51), e2524109122.
mla: Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary
Games.” Proceedings of the National Academy of Sciences, vol. 122, no.
51, National Academy of Sciences, 2025, p. e2524109122, doi:10.1073/pnas.2524109122.
short: J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences
122 (2025) e2524109122.
corr_author: '1'
date_created: 2025-12-28T23:01:26Z
date_published: 2025-12-15T00:00:00Z
date_updated: 2026-02-16T12:34:04Z
day: '15'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1073/pnas.2524109122
ec_funded: 1
external_id:
pmid:
- '41397136'
file:
- access_level: open_access
checksum: dd50b62a1efc28c0133fe9c11dbee53c
content_type: application/pdf
creator: dernst
date_created: 2025-12-29T09:36:50Z
date_updated: 2025-12-29T09:36:50Z
file_id: '20860'
file_name: 2025_PNAS_Svoboda.pdf
file_size: 2308124
relation: main_file
success: 1
file_date_updated: 2025-12-29T09:36:50Z
has_accepted_license: '1'
intvolume: ' 122'
issue: '51'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: e2524109122
pmid: 1
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Promoters of cooperation in evolutionary games
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 122
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20858'
abstract:
- lang: eng
text: Targeted antigen delivery to immune cells, particularly dendritic cells, has
emerged as a promising strategy to enhance therapeutic efficacy of vaccines, while
minimizing adverse effects associated with conventional immunization. In this
study, we use our previously described small glycomimetic molecule that is selectively
recognized by the Langerhans cell (LC)-specific surface receptor Langerin and
demonstrate specific delivery of protein antigens to these specialized dendritic
cells. Our results show that Langerin-mediated antigen delivery significantly
enhances the immune response in vivo, resulting in increased expansion and activation
of antigen-specific T cells, compared to immunization with unmodified antigen.
We demonstrate the feasibility of our LC-targeted platform for immune cell-specific
immunization with protein antigen and underscore the potential of LCs as an access
point for next-generation vaccines and immunotherapies.
acknowledgement: This project was generously supported by Seedfinancing (grant no.
P2282679) of the Austrian Bundesministerium für Digitalisierung und Wirtschaftsstandort
and the Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation,
und Technologie, handled by the Austrian Wirtschaftsservice (aws), as well as by
Life Science Call 2022 (grant no. FO999896442) of the Austrian Research Promotion
Agency (FFG). We thank Mag. Michael Schunn from the PCF of the Institute of Science
and Technology Austria for his continuous technical support.
article_processing_charge: No
article_type: original
author:
- first_name: Ramona
full_name: Rica, Ramona
last_name: Rica
- first_name: Klara
full_name: Klein, Klara
last_name: Klein
- first_name: Litty
full_name: Johnson, Litty
last_name: Johnson
- first_name: Gabriele
full_name: Carta, Gabriele
last_name: Carta
- first_name: Mirza
full_name: Sarcevic, Mirza
last_name: Sarcevic
- first_name: Freyja
full_name: Langer, Freyja
id: 3C1BE782-F248-11E8-B48F-1D18A9856A87
last_name: Langer
- first_name: Christoph
full_name: Rademacher, Christoph
last_name: Rademacher
- first_name: Robert
full_name: Wawrzinek, Robert
last_name: Wawrzinek
- first_name: Federica
full_name: Quattrone, Federica
last_name: Quattrone
- first_name: Florian
full_name: Sparber, Florian
last_name: Sparber
citation:
ama: Rica R, Klein K, Johnson L, et al. Langerhans cell-targeted protein delivery
enhances antigen-specific cellular immune response. Molecular Therapy.
doi:10.1016/j.ymthe.2025.10.008
apa: Rica, R., Klein, K., Johnson, L., Carta, G., Sarcevic, M., Langer, F., … Sparber,
F. (n.d.). Langerhans cell-targeted protein delivery enhances antigen-specific
cellular immune response. Molecular Therapy. Elsevier. https://doi.org/10.1016/j.ymthe.2025.10.008
chicago: Rica, Ramona, Klara Klein, Litty Johnson, Gabriele Carta, Mirza Sarcevic,
Freyja Langer, Christoph Rademacher, Robert Wawrzinek, Federica Quattrone, and
Florian Sparber. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific
Cellular Immune Response.” Molecular Therapy. Elsevier, n.d. https://doi.org/10.1016/j.ymthe.2025.10.008.
ieee: R. Rica et al., “Langerhans cell-targeted protein delivery enhances
antigen-specific cellular immune response,” Molecular Therapy. Elsevier.
ista: Rica R, Klein K, Johnson L, Carta G, Sarcevic M, Langer F, Rademacher C, Wawrzinek
R, Quattrone F, Sparber F. Langerhans cell-targeted protein delivery enhances
antigen-specific cellular immune response. Molecular Therapy.
mla: Rica, Ramona, et al. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific
Cellular Immune Response.” Molecular Therapy, Elsevier, doi:10.1016/j.ymthe.2025.10.008.
short: R. Rica, K. Klein, L. Johnson, G. Carta, M. Sarcevic, F. Langer, C. Rademacher,
R. Wawrzinek, F. Quattrone, F. Sparber, Molecular Therapy (n.d.).
date_created: 2025-12-28T23:01:26Z
date_published: 2025-10-04T00:00:00Z
date_updated: 2025-12-29T09:55:05Z
day: '04'
department:
- _id: PreCl
doi: 10.1016/j.ymthe.2025.10.008
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2025.05.05.652195
month: '10'
oa: 1
oa_version: Preprint
publication: Molecular Therapy
publication_identifier:
eissn:
- 1525-0024
issn:
- 1525-0016
publication_status: inpress
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Langerhans cell-targeted protein delivery enhances antigen-specific cellular
immune response
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20859'
abstract:
- lang: eng
text: Effective immune responses rely on the efficient migration of leukocytes.
Yet, how temperature regulates migration dynamics at the single-cell level has
remained poorly understood. Using zebrafish embryos and mouse tissue explants,
we found that temperature positively regulates leukocyte migration speed, exploration,
and arrival frequencies to wounds and lymph vessels. Complementary 2D and 3D cultures
revealed that this thermokinetic control of cell migration is conserved across
immune cell types, independently of the 3D tissue environment. By applying precise
(sub-)cellular temperature modulation, we identified a rapid and reversible thermo-response
that depends on myosin II activity. Small physiological increases in temperature
(1°C –2°C), as present during fever-like conditions, profoundly increased immune
responses by accelerating arrival times at lymphatic vessels and tissue wounds.
These findings identify myosin-II-dependent actomyosin contractility as a critical
mechanical structure regulating single-cell thermo-adaptability, with physiological
implications for tuning the speed of immune responses in vivo.
acknowledged_ssus:
- _id: NanoFab
acknowledgement: 'The authors would like to acknowledge the Super Resolution Light
Microcopy and Nanoscopy (SLN) Facility of ICFO for their support with imaging experiments,
Johann Osmond (Nanofabrication laboratory, ICFO) for the design and production of
molds for generating confinement coverslip, Merche Rivas for cell culture of immune
cells and further support from the CRG Core Facilities for Genomics and Advanced
Light Microscopy. We would like to thank Michael Sixt for discussions on this work
and the Quidant, Ruprecht, and Wieser lab members for critical reading of the manuscript.
This research was supported by the Scientific Service Units (SSU) of IST-Austria
through resources provided by the Nanofabrication Facility (NFF). C.A. acknowledges
the funding from the European Union’s Horizon 2020 research and innovation programme
under the Marie Skłodowska-Curie grant agreement no 847517 and V.V. from the ICFOstepstone
– PhD Programme funded by the European Union’s Horizon 2020 research and innovation
programme under the Marie Skłodowska-Curie grant agreement no 665884. S.W. acknowledges
support through the Spanish Ministry of Economy and Competitiveness via MINECO’s
Plan Nacional (BFU2017-86296-P). V.R. acknowledges funding from the European Union’s
HORIZON-EIC-2021-PATHFINDEROPEN program under grant agreement no. 101046620 and
European Union''s Horizon Europe program under the grant agreement no. 101072123.
E.K. acknowledges funding by a fellowship of the Ministry of Innovation, Science
and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069) and the Deutsche
Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence
Strategy – EXC 2151 – 390873048 and by the TRA Life and Health (University of Bonn)
as part of the Excellence Strategy of the federal and state governments.'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Iván
full_name: Company-Garrido, Iván
last_name: Company-Garrido
- first_name: Alberto
full_name: Zurita Carpio, Alberto
last_name: Zurita Carpio
- first_name: Mariona
full_name: Colomer-Rosell, Mariona
last_name: Colomer-Rosell
- first_name: Bernard
full_name: Ciraulo, Bernard
last_name: Ciraulo
- first_name: Ronja
full_name: Molkenbur, Ronja
last_name: Molkenbur
- first_name: Peter
full_name: Lanzerstorfer, Peter
last_name: Lanzerstorfer
- first_name: Fabio
full_name: Pezzano, Fabio
last_name: Pezzano
- first_name: Costanza
full_name: Agazzi, Costanza
last_name: Agazzi
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Saumey
full_name: Jain, Saumey
last_name: Jain
- first_name: Jeroen M.
full_name: Jacques, Jeroen M.
last_name: Jacques
- first_name: Valeria
full_name: Venturini, Valeria
last_name: Venturini
- first_name: Christian
full_name: Knapp, Christian
last_name: Knapp
- first_name: Yufei
full_name: Xie, Yufei
last_name: Xie
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Julian
full_name: Weghuber, Julian
last_name: Weghuber
- first_name: Marcel
full_name: Schaaf, Marcel
last_name: Schaaf
- first_name: Romain
full_name: Quidant, Romain
last_name: Quidant
- first_name: Eva
full_name: Kiermaier, Eva
id: 3EB04B78-F248-11E8-B48F-1D18A9856A87
last_name: Kiermaier
orcid: 0000-0001-6165-5738
- first_name: Jaime
full_name: Ortega Arroyo, Jaime
last_name: Ortega Arroyo
- first_name: Verena
full_name: Ruprecht, Verena
id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
last_name: Ruprecht
orcid: 0000-0003-4088-8633
- first_name: Stefan
full_name: Wieser, Stefan
id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
last_name: Wieser
orcid: 0000-0002-2670-2217
citation:
ama: Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, et al. Myosin II regulates
cellular thermo-adaptability and the efficiency of immune responses. Developmental
Cell. 2025. doi:10.1016/j.devcel.2025.10.006
apa: Company-Garrido, I., Zurita Carpio, A., Colomer-Rosell, M., Ciraulo, B., Molkenbur,
R., Lanzerstorfer, P., … Wieser, S. (2025). Myosin II regulates cellular thermo-adaptability
and the efficiency of immune responses. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2025.10.006
chicago: Company-Garrido, Iván, Alberto Zurita Carpio, Mariona Colomer-Rosell, Bernard
Ciraulo, Ronja Molkenbur, Peter Lanzerstorfer, Fabio Pezzano, et al. “Myosin II
Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.”
Developmental Cell. Elsevier, 2025. https://doi.org/10.1016/j.devcel.2025.10.006.
ieee: I. Company-Garrido et al., “Myosin II regulates cellular thermo-adaptability
and the efficiency of immune responses,” Developmental Cell. Elsevier,
2025.
ista: Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, Ciraulo B, Molkenbur
R, Lanzerstorfer P, Pezzano F, Agazzi C, Hauschild R, Jain S, Jacques JM, Venturini
V, Knapp C, Xie Y, Merrin J, Weghuber J, Schaaf M, Quidant R, Kiermaier E, Ortega
Arroyo J, Ruprecht V, Wieser S. 2025. Myosin II regulates cellular thermo-adaptability
and the efficiency of immune responses. Developmental Cell.
mla: Company-Garrido, Iván, et al. “Myosin II Regulates Cellular Thermo-Adaptability
and the Efficiency of Immune Responses.” Developmental Cell, Elsevier,
2025, doi:10.1016/j.devcel.2025.10.006.
short: I. Company-Garrido, A. Zurita Carpio, M. Colomer-Rosell, B. Ciraulo, R. Molkenbur,
P. Lanzerstorfer, F. Pezzano, C. Agazzi, R. Hauschild, S. Jain, J.M. Jacques,
V. Venturini, C. Knapp, Y. Xie, J. Merrin, J. Weghuber, M. Schaaf, R. Quidant,
E. Kiermaier, J. Ortega Arroyo, V. Ruprecht, S. Wieser, Developmental Cell (2025).
date_created: 2025-12-28T23:01:27Z
date_published: 2025-11-04T00:00:00Z
date_updated: 2025-12-29T09:23:58Z
day: '04'
ddc:
- '570'
department:
- _id: Bio
- _id: NanoFab
doi: 10.1016/j.devcel.2025.10.006
external_id:
pmid:
- '41192429'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2025.10.006
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Myosin II regulates cellular thermo-adaptability and the efficiency of immune
responses
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...