@article{12312, abstract = {Let $\ell$ be a prime number. We classify the subgroups $G$ of $\operatorname{Sp}_4(\mathbb{F}_\ell)$ and $\operatorname{GSp}_4(\mathbb{F}_\ell)$ that act irreducibly on $\mathbb{F}_\ell^4$, but such that every element of $G$ fixes an $\mathbb{F}_\ell$-vector subspace of dimension 1. We use this classification to prove that the local-global principle for isogenies of degree $\ell$ between abelian surfaces over number fields holds in many cases -- in particular, whenever the abelian surface has non-trivial endomorphisms and $\ell$ is large enough with respect to the field of definition. Finally, we prove that there exist arbitrarily large primes $\ell$ for which some abelian surface $A/\mathbb{Q}$ fails the local-global principle for isogenies of degree $\ell$.}, author = {Lombardo, Davide and Verzobio, Matteo}, issn = {1420-9020}, journal = {Selecta Mathematica}, number = {2}, publisher = {Springer Nature}, title = {{On the local-global principle for isogenies of abelian surfaces}}, doi = {10.1007/s00029-023-00908-0}, volume = {30}, year = {2024}, } @article{12485, abstract = {In this paper we introduce the critical variational setting for parabolic stochastic evolution equations of quasi- or semi-linear type. Our results improve many of the abstract results in the classical variational setting. In particular, we are able to replace the usual weak or local monotonicity condition by a more flexible local Lipschitz condition. Moreover, the usual growth conditions on the multiplicative noise are weakened considerably. Our new setting provides general conditions under which local and global existence and uniqueness hold. Moreover, we prove continuous dependence on the initial data. We show that many classical SPDEs, which could not be covered by the classical variational setting, do fit in the critical variational setting. In particular, this is the case for the Cahn-Hilliard equations, tamed Navier-Stokes equations, and Allen-Cahn equation.}, author = {Agresti, Antonio and Veraar, Mark}, issn = {1432-2064}, journal = {Probability Theory and Related Fields}, pages = {957--1015}, publisher = {Springer Nature}, title = {{The critical variational setting for stochastic evolution equations}}, doi = {10.1007/s00440-023-01249-x}, volume = {188}, year = {2024}, } @article{12486, abstract = {This paper is concerned with the problem of regularization by noise of systems of reaction–diffusion equations with mass control. It is known that strong solutions to such systems of PDEs may blow-up in finite time. Moreover, for many systems of practical interest, establishing whether the blow-up occurs or not is an open question. Here we prove that a suitable multiplicative noise of transport type has a regularizing effect. More precisely, for both a sufficiently noise intensity and a high spectrum, the blow-up of strong solutions is delayed up to an arbitrary large time. Global existence is shown for the case of exponentially decreasing mass. The proofs combine and extend recent developments in regularization by noise and in the Lp(Lq)-approach to stochastic PDEs, highlighting new connections between the two areas.}, author = {Agresti, Antonio}, issn = {2194-041X}, journal = {Stochastics and Partial Differential Equations: Analysis and Computations}, pages = {1907--1981}, publisher = {Springer Nature}, title = {{Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion equations}}, doi = {10.1007/s40072-023-00319-4}, volume = {12}, year = {2024}, } @article{13093, abstract = {The direct, solid state, and reversible conversion between heat and electricity using thermoelectric devices finds numerous potential uses, especially around room temperature. However, the relatively high material processing cost limits their real applications. Silver selenide (Ag2Se) is one of the very few n-type thermoelectric (TE) materials for room-temperature applications. Herein, we report a room temperature, fast, and aqueous-phase synthesis approach to produce Ag2Se, which can be extended to other metal chalcogenides. These materials reach TE figures of merit (zT) of up to 0.76 at 380 K. To improve these values, bismuth sulfide (Bi2S3) particles also prepared in an aqueous solution are incorporated into the Ag2Se matrix. In this way, a series of Ag2Se/Bi2S3 composites with Bi2S3 wt % of 0.5, 1.0, and 1.5 are prepared by solution blending and hot-press sintering. The presence of Bi2S3 significantly improves the Seebeck coefficient and power factor while at the same time decreasing the thermal conductivity with no apparent drop in electrical conductivity. Thus, a maximum zT value of 0.96 is achieved in the composites with 1.0 wt % Bi2S3 at 370 K. Furthermore, a high average zT value (zTave) of 0.93 in the 300–390 K range is demonstrated.}, author = {Nan, Bingfei and Li, Mengyao and Zhang, Yu and Xiao, Ke and Lim, Khak Ho and Chang, Cheng and Han, Xu and Zuo, Yong and Li, Junshan and Arbiol, Jordi and Llorca, Jordi and Ibáñez, Maria and Cabot, Andreu}, issn = {2637-6113}, journal = {ACS Applied Electronic Materials}, number = {5}, pages = {2807--215}, publisher = {American Chemical Society}, title = {{Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature}}, doi = {10.1021/acsaelm.3c00055}, volume = {6}, year = {2024}, } @article{13129, abstract = {We study the representative volume element (RVE) method, which is a method to approximately infer the effective behavior ahom of a stationary random medium. The latter is described by a coefficient field a(x) generated from a given ensemble ⟨⋅⟩ and the corresponding linear elliptic operator −∇⋅a∇. In line with the theory of homogenization, the method proceeds by computing d=3 correctors (d denoting the space dimension). To be numerically tractable, this computation has to be done on a finite domain: the so-called representative volume element, i.e., a large box with, say, periodic boundary conditions. The main message of this article is: Periodize the ensemble instead of its realizations. By this, we mean that it is better to sample from a suitably periodized ensemble than to periodically extend the restriction of a realization a(x) from the whole-space ensemble ⟨⋅⟩. We make this point by investigating the bias (or systematic error), i.e., the difference between ahom and the expected value of the RVE method, in terms of its scaling w.r.t. the lateral size L of the box. In case of periodizing a(x), we heuristically argue that this error is generically O(L−1). In case of a suitable periodization of ⟨⋅⟩ , we rigorously show that it is O(L−d). In fact, we give a characterization of the leading-order error term for both strategies and argue that even in the isotropic case it is generically non-degenerate. We carry out the rigorous analysis in the convenient setting of ensembles ⟨⋅⟩ of Gaussian type, which allow for a straightforward periodization, passing via the (integrable) covariance function. This setting has also the advantage of making the Price theorem and the Malliavin calculus available for optimal stochastic estimates of correctors. We actually need control of second-order correctors to capture the leading-order error term. This is due to inversion symmetry when applying the two-scale expansion to the Green function. As a bonus, we present a stream-lined strategy to estimate the error in a higher-order two-scale expansion of the Green function.}, author = {Clozeau, Nicolas and Josien, Marc and Otto, Felix and Xu, Qiang}, issn = {1615-3383}, journal = {Foundations of Computational Mathematics}, pages = {1305--1387}, publisher = {Springer Nature}, title = {{Bias in the representative volume element method: Periodize the ensemble instead of its realizations}}, doi = {10.1007/s10208-023-09613-y}, volume = {24}, year = {2024}, } @article{13271, abstract = {In this paper, we prove the convexity of trace functionals (A,B,C)↦Tr|BpACq|s, for parameters (p, q, s) that are best possible, where B and C are any n-by-n positive-definite matrices, and A is any n-by-n matrix. We also obtain the monotonicity versions of trace functionals of this type. As applications, we extend some results in Carlen et al. (Linear Algebra Appl 490:174–185, 2016), Hiai and Petz (Publ Res Inst Math Sci 48(3):525-542, 2012) and resolve a conjecture in Al-Rashed and Zegarliński (Infin Dimens Anal Quantum Probab Relat Top 17(4):1450029, 2014) in the matrix setting. Other conjectures in Al-Rashed and Zegarliński (Infin Dimens Anal Quantum Probab Relat Top 17(4):1450029, 2014) will also be discussed. We also show that some related trace functionals are not concave in general. Such concavity results were expected to hold in different problems.}, author = {Zhang, Haonan}, issn = {1424-0637}, journal = {Annales Henri Poincare}, pages = {2087--2106}, publisher = {Springer Nature}, title = {{Some convexity and monotonicity results of trace functionals}}, doi = {10.1007/s00023-023-01345-7}, volume = {25}, year = {2024}, } @article{13318, abstract = {Bohnenblust–Hille inequalities for Boolean cubes have been proven with dimension-free constants that grow subexponentially in the degree (Defant et al. in Math Ann 374(1):653–680, 2019). Such inequalities have found great applications in learning low-degree Boolean functions (Eskenazis and Ivanisvili in Proceedings of the 54th annual ACM SIGACT symposium on theory of computing, pp 203–207, 2022). Motivated by learning quantum observables, a qubit analogue of Bohnenblust–Hille inequality for Boolean cubes was recently conjectured in Rouzé et al. (Quantum Talagrand, KKL and Friedgut’s theorems and the learnability of quantum Boolean functions, 2022. arXiv preprint arXiv:2209.07279). The conjecture was resolved in Huang et al. (Learning to predict arbitrary quantum processes, 2022. arXiv preprint arXiv:2210.14894). In this paper, we give a new proof of these Bohnenblust–Hille inequalities for qubit system with constants that are dimension-free and of exponential growth in the degree. As a consequence, we obtain a junta theorem for low-degree polynomials. Using similar ideas, we also study learning problems of low degree quantum observables and Bohr’s radius phenomenon on quantum Boolean cubes.}, author = {Volberg, Alexander and Zhang, Haonan}, issn = {1432-1807}, journal = {Mathematische Annalen}, pages = {1657--1676}, publisher = {Springer Nature}, title = {{Noncommutative Bohnenblust–Hille inequalities}}, doi = {10.1007/s00208-023-02680-0}, volume = {389}, year = {2024}, } @misc{19800, abstract = {This archive contains all the code and data necessary to reproduce the results presented in the "Mapping the attractor landscape of Boolean networks" paper.}, author = {trinh, Van Giang and Park, Kyu Hyong and Pastva, Samuel and Rozum, Jordan}, publisher = {Zenodo}, title = {{Mapping the attractor landscape of Boolean networks}}, doi = {10.5281/ZENODO.13854759}, year = {2024}, } @misc{19884, abstract = {This is Marlin, a Mixed Auto-Regressive Linear kernel (and the name of one of the planet's fastest fish), an extremely optimized FP16xINT4 matmul kernel aimed at LLM inference that can deliver close to ideal (4x) speedups up to batchsizes of 16-32 tokens (in contrast to the 1-2 tokens of prior work with comparable speedup). Additionally, it includes Sparse-Marlin, an extension of the MARLIN kernels adding support to 2:4 weight sparsity, achieving 5.3x speedups on NVIDIA GPUs (Ampere/Ada).}, author = {Frantar, Elias and Castro, Roberto and Chen, Jiale and Hoefler, Torsten and Alistarh, Dan-Adrian}, publisher = {Zenodo}, title = {{MARLIN: Mixed-precision auto-regressive parallel inference on Large Language Models}}, doi = {10.5281/ZENODO.14213091}, year = {2024}, } @article{20039, abstract = {This Comment presents a high-level protocol for data harmonization within large cohorts, in which it postulates four main steps including (1) expert review, (2) pre-statistical harmonization, (3) statistical harmonization, and (4) validation.}, author = {Neidhart, Maja and Kjelkenes, Rikka and Jansone, Karina and Rehák Bučková, Barbora and Holz, Nathalie and Nees, Frauke and Walter, Henrik and Schumann, Gunter and Rapp, Michael A. and Banaschewski, Tobias and Schwarz, Emanuel and Marquand, Andre and Ogoh, George and Stahl, Bernd and Young, Allan H. and Desrivières, Sylvane and Clinton, Nicholas and Thompson, Paul and Schwalber, Ameli and Liu, Jingyu and Calhoun, Vince and Chang, Xiao and Xia, Yunman and Gong, Yanting and Jia, Tianye and Renner, Paul and Hese, Sören and Giner, Arantxa and Sanchez, Mavi and Alvarez, Elena and Spanlang, Bernhard and Pearmund, Charlie and Athanasiadis, Anastasios Polykarpos and Otten, Lisa and Pitel, Séverine and Petkoski, Spase and Jirsa, Viktor and Schmitt, Karen and Wilbertz, Johannes and Patraskaki, Myrto and Sommer, Peter and Heilmann-Heimbach, Stefanie and Mathey, Carina M. and Miller, Abigail and Claus, Isabelle and Nöthen, Markus M. and Hoffmann, Per and Forstner, Andreas J. and Pastor, Alvaro and Gallego, Jaime and Orosa, Francisco Eiroa and Viapiana, Guillem Feixas and Slater, Mel and Marr, Lena and Novarino, Gaia and Böttger, Sarah Jane and Tschorn, Mira and Rapp, Michael and Ask, Helga and Fernandez, Sara and Van Der Meer, Dennis and Westlye, Lars T. and Andreassen, Ole A. and Aden, Rieke and Seefried, Beke and Siehl, Sebastian and Nees, Frauke and Stringaris, Argyris and Tost, Heike and Meyer-Lindenberg, Andreas and Christmann, Nina and Banks, Jamie and Schepanski, Kerstin and Schütz, Tatjana and Taron, Ulrike Helene and Eils, Roland and Roy, Jean Charles and Lett, Tristram A. and Kebir, Hedi and Polemiti, Elli and Hitchen, Esther and Jentsch, Marcel and Serin, Emin and Bernas, Antoine and Vaidya, Nilakshi and Twardziok, Sven and Ralser, Markus and Heinz, Andreas}, issn = {2731-6076}, journal = {Nature Mental Health}, number = {10}, pages = {1134--1137}, publisher = {Springer Nature}, title = {{A protocol for data harmonization in large cohorts}}, doi = {10.1038/s44220-024-00315-0}, volume = {2}, year = {2024}, } @misc{20057, abstract = {In article number 2305128, Qing Sun, Shang Wang, Yanhong Tian, Andreu Cabot, and co-workers report an investigation of the energy-storage mechanism of a layered Bi2Te3-based cathode for aqueous zinc-ion batteries (ZIBs). They demonstrate that the zinc ion is not inserted into the cathode as previously assumed; in contrast, proton charge-storage dominates the process. They also demonstrate the great application prospects of aqueous ZIBs in flexible electronics via jet printing technology.}, author = {Zeng, Guifang and Sun, Qing and Horta, Sharona and Wang, Shang and Lu, Xuan and Zhang, Chao Yue and Li, Jing and Li, Junshan and Ci, Lijie and Tian, Yanhong and Ibáñez, Maria and Cabot, Andreu}, booktitle = {Advanced Materials}, issn = {1521-4095}, number = {1}, publisher = {Wiley}, title = {{A layered Bi2Te3@PPy cathode for aqueous Zinc‐Ion batteries: Mechanism and application in printed flexible batteries}}, doi = {10.1002/adma.202470004}, volume = {36}, year = {2024}, } @misc{20121, abstract = {PyDaddy is an open source package which is a key contribution of the manuscript Nabeel et al, arXiv:2205.02645. The basic scientific premise for this package is to discover the nature of stochasticity in ecological time series datasets. It is well known that the stochasticity can affect the dynamics of ecological systems in counter-intuitive ways. Without understanding the equations (typically, in the form of stochastic differential equations or SDEs, in short) that govern the dynamics of populations or ecosystems, it's challenging to determine the impact of randomness on real datasets. In this manuscript and accompanying package, we introduce a methodology for discovering equations (SDEs) that transforms time series data of state variables into stochastic differential equations. This approach merges traditional stochastic calculus with modern equation-discovery techniques. We showcase the generality of our method through various applications and discuss its limitations and potential pitfalls, offering diagnostic measures to address these challenges.}, author = {Nabeel, Arshed and Karichannavar, Ashwin and Palathingal, Shuaib and Jhawar, Jitesh and Brückner, David and Danny Raj, Masila and Guttal, Vishwesha}, publisher = {Zenodo}, title = {{PyDaddy: A Python Package for Discovering SDEs from Time Series Data}}, doi = {10.5281/ZENODO.7137151}, year = {2024}, } @article{20156, abstract = {Integrative analyses that incorporate different levels of ‘-omics’ data represent a powerful tool for deciphering the biological mechanisms that underlie environmental influences on mental health and disease. This Comment highlights various aspects of such multi-omics approaches, using the example of the EU-funded environMENTAL project.}, author = {Desrivières, Sylvane and Miller, Abigail and Mathey, Carina M. and Yu, Xinyang and Chen, Di and Agunbiade, Kofoworola and Heilmann-Heimbach, Stefanie and Forstner, Andreas J. and Schumann, Gunter and Hoffmann, Per and Nöthen, Markus M. and Ogoh, George and Stahl, Bernd and Young, Allan H. and Clinton, Nicholas and Thompson, Paul and Schwalber, Ameli and Liu, Jingyu and Calhoun, Vince and Chang, Xiao and Xia, Yunman and Gong, Yanting and Jia, Tianye and Renner, Paul and Hese, Sören and Giner, Arantxa and Sanchez, Mavi and Alvarez, Elena and Spanlang, Bernhard and Pearmund, Charlie and Athanasiadis, Anastasios Polykarpos and Otten, Lisa and Pitel, Séverine and Petkoski, Spase and Jirsa, Viktor and Schmitt, Karen and Wilbertz, Johannes and Patraskaki, Myrto and Sommer, Peter and Claus, Isabelle and Pastor, Alvaro and Gallego, Jaime and Orosa, Francisco Eiroa and Viapiana, Guillem Feixas and Slater, Mel and Marr, Lena and Novarino, Gaia and Marquand, Andre and Böttger, Sarah Jane and Tschorn, Mira and Rapp, Michael and Ask, Helga and Kjelkenes, Rikka and Fernandez, Sara and Van Der Meer, Dennis and Westlye, Lars T. and Andreassen, Ole A. and Aden, Rieke and Seefried, Beke and Siehl, Sebastian and Nees, Frauke and Neidhart, Maja and Stringaris, Argyris and Schwarz, Emanuel and Holz, Nathalie and Tost, Heike and Meyer-Lindenberg, Andreas and Christmann, Nina and Jansone, Karina and Banaschewski, Tobias and Banks, Jamie and Schepanski, Kerstin and Schütz, Tatjana and Taron, Ulrike Helene and Eils, Roland and Roy, Jean Charles and Lett, Tristram A. and Kebir, Hedi and Polemiti, Elli and Hitchen, Esther and Jentsch, Marcel and Serin, Emin and Bernas, Antoine and Vaidya, Nilakshi and Twardziok, Sven and Ralser, Markus and Heinz, Andreas and Walter, Henrik}, issn = {2731-6076}, journal = {Nature Mental Health}, number = {10}, pages = {1131--1133}, publisher = {Springer Nature}, title = {{Multi-omics analyses of the environMENTAL project provide insights into mental health and disease}}, doi = {10.1038/s44220-024-00317-y}, volume = {2}, year = {2024}, } @article{20157, abstract = {The focus of much of contemporary research ethics is on compliance with established protocols. However, large data-driven neuroscience research raises new ethical concerns that have no agreed-upon solution. Here we reflect on these challenges and propose better integration of public and patient involvement in this evolving landscape.}, author = {Stahl, Bernd and Ogoh, George and Schumann, Gunter and Walter, Henrik and Stahl, Bernd and Young, Allan H. and Desrivières, Sylvane and Clinton, Nicholas and Thompson, Paul and Schwalber, Ameli and Liu, Jingyu and Calhoun, Vince and Chang, Xiao and Xia, Yunman and Gong, Yanting and Jia, Tianye and Renner, Paul and Hese, Sören and Giner, Arantxa and Sanchez, Mavi and Alvarez, Elena and Spanlang, Bernhard and Pearmund, Charlie and Athanasiadis, Anastasios Polykarpos and Otten, Lisa and Pitel, Séverine and Petkoski, Spase and Jirsa, Viktor and Schmitt, Karen and Wilbertz, Johannes and Patraskaki, Myrto and Sommer, Peter and Heilmann-Heimbach, Stefanie and Mathey, Carina M. and Miller, Abigail and Claus, Isabelle and Nöthen, Markus M. and Hoffmann, Per and Forstner, Andreas J. and Pastor, Alvaro and Gallego, Jaime and Orosa, Francisco Eiroa and Viapiana, Guillem Feixas and Slater, Mel and Marr, Lena and Novarino, Gaia and Marquand, Andre and Böttger, Sarah Jane and Tschorn, Mira and Rapp, Michael and Ask, Helga and Kjelkenes, Rikka and Fernandez, Sara and Van Der Meer, Dennis and Westlye, Lars T. and Andreassen, Ole A. and Aden, Rieke and Seefried, Beke and Siehl, Sebastian and Nees, Frauke and Neidhart, Maja and Stringaris, Argyris and Schwarz, Emanuel and Holz, Nathalie and Tost, Heike and Meyer-Lindenberg, Andreas and Christmann, Nina and Jansone, Karina and Banaschewski, Tobias and Banks, Jamie and Schepanski, Kerstin and Schütz, Tatjana and Taron, Ulrike Helene and Eils, Roland and Roy, Jean Charles and Lett, Tristram A. and Kebir, Hedi and Polemiti, Elli and Hitchen, Esther and Jentsch, Marcel and Serin, Emin and Bernas, Antoine and Vaidya, Nilakshi and Twardziok, Sven and Ralser, Markus and Heinz, Andreas and Walter, Henrik}, issn = {2731-6076}, journal = {Nature Mental Health}, number = {10}, publisher = {Springer Nature}, title = {{Rethinking ethics in interdisciplinary and big data-driven neuroscience projects}}, doi = {10.1038/s44220-024-00320-3}, volume = {2}, year = {2024}, } @inproceedings{18755, abstract = {A universalthresholdizer (UT), constructed from a threshold fully homomorphic encryption by Boneh et. al , Crypto 2018, is a general framework for universally thresholdizing many cryptographic schemes. However, their framework is insufficient to construct strongly secure threshold schemes, such as threshold signatures and threshold public-key encryption, etc. In this paper, we strengthen the security definition for a universal thresholdizer and propose a scheme which satisfies our stronger security notion. Our UT scheme is an improvement of Boneh et. al ’s construction at the level of threshold fully homomorphic encryption using a key homomorphic pseudorandom function. We apply our strongly secure UT scheme to construct strongly secure threshold signatures and threshold public-key encryption.}, author = {Ebrahimi, Ehsan and Yadav, Anshu}, booktitle = {30th International Conference on the Theory and Application of Cryptology and Information Security}, isbn = {9789819608904}, issn = {1611-3349}, location = {Kolkata, India}, pages = {207--239}, publisher = {Springer Nature}, title = {{Strongly secure universal thresholdizer}}, doi = {10.1007/978-981-96-0891-1_7}, volume = {15486}, year = {2024}, } @inproceedings{18756, abstract = {The evasive LWE assumption, proposed by Wee [Eurocrypt’22 Wee] for constructing a lattice-based optimal broadcast encryption, has shown to be a powerful assumption, adopted by subsequent works to construct advanced primitives ranging from ABE variants to obfuscation for null circuits. However, a closer look reveals significant differences among the precise assumption statements involved in different works, leading to the fundamental question of how these assumptions compare to each other. In this work, we initiate a more systematic study on evasive LWE assumptions: (i) Based on the standard LWE assumption, we construct simple counterexamples against three private-coin evasive LWE variants, used in [Crypto’22 Tsabary, Asiacrypt’22 VWW, Crypto’23 ARYY] respectively, showing that these assumptions are unlikely to hold. (ii) Based on existing evasive LWE variants and our counterexamples, we propose and define three classes of plausible evasive LWE assumptions, suitably capturing all existing variants for which we are not aware of non-obfuscation-based counterexamples. (iii) We show that under our assumption formulations, the security proofs of [Asiacrypt’22 VWW] and [Crypto’23 ARYY] can be recovered, and we reason why the security proof of [Crypto’22 Tsabary] is also plausibly repairable using an appropriate evasive LWE assumption.}, author = {Brzuska, Chris and Ünal, Akin and Woo, Ivy K.Y.}, booktitle = {30th International Conference on the Theory and Application of Cryptology and Information Security}, isbn = {9789819608935}, issn = {1611-3349}, location = {Kolkata, India}, pages = {418--449}, publisher = {Springer Nature}, title = {{Evasive LWE assumptions: Definitions, classes, and counterexamples}}, doi = {10.1007/978-981-96-0894-2_14}, volume = {15487}, year = {2024}, } @article{18757, abstract = {Segmentation is a critical data processing step in many applications of cryo-electron tomography. Downstream analyses, such as subtomogram averaging, are often based on segmentation results, and are thus critically dependent on the availability of open-source software for accurate as well as high-throughput tomogram segmentation. There is a need for more user-friendly, flexible, and comprehensive segmentation software that offers an insightful overview of all steps involved in preparing automated segmentations. Here, we present Ais: a dedicated tomogram segmentation package that is geared towards both high performance and accessibility, available on GitHub. In this report, we demonstrate two common processing steps that can be greatly accelerated with Ais: particle picking for subtomogram averaging, and generating many-feature segmentations of cellular architecture based on in situ tomography data. Featuring comprehensive annotation, segmentation, and rendering functionality, as well as an open repository for trained models at aiscryoet.org, we hope that Ais will help accelerate research and dissemination of data involving cryoET.}, author = {Last, Mart G.F. and Abendstein, Leoni and Voortman, Lenard M. and Sharp, Thomas H.}, issn = {2050-084X}, journal = {eLife}, publisher = {eLife Sciences Publications}, title = {{Streamlining segmentation of cryo-electron tomography datasets with Ais}}, doi = {10.7554/eLife.98552}, volume = {13}, year = {2024}, } @inproceedings{18758, abstract = {MaxCut is a classical NP-complete problem and a crucial building block in many combinatorial algorithms. The famous Edwards-Erdős bound states that any connected graph on n vertices with m edges contains a cut of size at least m/2+(n-1)/4. Crowston, Jones and Mnich [Algorithmica, 2015] showed that the MaxCut problem on simple connected graphs admits an FPT algorithm, where the parameter k is the difference between the desired cut size c and the lower bound given by the Edwards-Erdős bound. This was later improved by Etscheid and Mnich [Algorithmica, 2017] to run in parameterized linear time, i.e., f(k)⋅ O(m). We improve upon this result in two ways: Firstly, we extend the algorithm to work also for multigraphs (alternatively, graphs with positive integer weights). Secondly, we change the parameter; instead of the difference to the Edwards-Erdős bound, we use the difference to the Poljak-Turzík bound. The Poljak-Turzík bound states that any weighted graph G has a cut of size at least (w(G))/2+(w_MSF(G))/4, where w(G) denotes the total weight of G, and w_MSF(G) denotes the weight of its minimum spanning forest. In connected simple graphs the two bounds are equivalent, but for multigraphs the Poljak-Turzík bound can be larger and thus yield a smaller parameter k. Our algorithm also runs in parameterized linear time, i.e., f(k)⋅ O(m+n).}, author = {Lill, Jonas and Petrova, Kalina H and Weber, Simon}, booktitle = {19th International Symposium on Parameterized and Exact Computation}, isbn = {9783959773539}, issn = {1868-8969}, location = {Egham, United Kingdom}, publisher = {Schloss Dagstuhl - Leibniz-Zentrum für Informatik}, title = {{Linear-time MaxCut in multigraphs parameterized above the Poljak-Turzík bound}}, doi = {10.4230/LIPIcs.IPEC.2024.2}, volume = {321}, year = {2024}, } @article{18760, abstract = {With the remarkable sensitivity and resolution of JWST in the infrared, measuring rest-optical kinematics of galaxies at z > 5 has become possible for the first time. This study pilots a new method for measuring galaxy dynamics for highly multiplexed, unbiased samples by combining FRESCO NIRCam grism spectroscopy and JADES medium-band imaging. Here we present one of the first JWST kinematic measurements for a galaxy at z > 5. We find a significant velocity gradient, which, if interpreted as rotation, yields Vrot = 305 ± 70 km s−1, and we hence refer to this galaxy as Twister-z5. With a rest-frame optical effective radius of re = 2.25 kpc, the high rotation velocity in this galaxy is not due to a compact size, as may be expected in the early Universe, but rather to a high total mass, (math formula). This is a factor of roughly 10× higher than the stellar mass within re. We also observe that the radial Hα equivalent width profile and the specific star formation rate map from resolved stellar population modeling are centrally depressed by a factor of ∼1.5 from the center to re. Combined with the morphology of the line-emitting gas in comparison to the continuum, this centrally suppressed star formation is consistent with a star-forming disk surrounding a bulge growing inside out. While large, rapidly rotating disks are common to z ∼ 2, the existence of one after only 1 Gyr of cosmic time, shown for the first time in ionized gas, adds to the growing evidence that some galaxies matured earlier than expected in the history of the Universe.}, author = {Nelson, Erica and Brammer, Gabriel and Giménez-Arteaga, Clara and Oesch, Pascal A. and Naidu, Rohan P. and Übler, Hannah and Matharu, Jasleen and Shapley, Alice E. and Whitaker, Katherine E. and Wisnioski, Emily and Förster Schreiber, Natascha M. and Smit, Renske and Van Dokkum, Pieter and Chisholm, John and Endsley, Ryan and Hartley, Abigail I. and Gibson, Justus and Giovinazzo, Emma and Illingworth, Garth and Labbe, Ivo and Maseda, Michael V. and Matthee, Jorryt J and Covelo Paz, Alba and Price, Sedona H. and Reddy, Naveen A. and Shivaei, Irene and Weibel, Andrea and Wuyts, Stijn and Xiao, Mengyuan and Alberts, Stacey and Baker, William M. and Bunker, Andrew J. and Cameron, Alex J. and Charlot, Stephane and Eisenstein, Daniel J. and De Graaff, Anna and Ji, Zhiyuan and Johnson, Benjamin D. and Jones, Gareth C. and Maiolino, Roberto and Robertson, Brant and Sandles, Lester and Suess, Katherine A. and Tacchella, Sandro and Williams, Christina C. and Witstok, Joris}, issn = {2041-8213}, journal = {Astrophysical Journal Letters}, number = {2}, publisher = {IOP Publishing}, title = {{Ionized gas kinematics with FRESCO: An extended, massive, rapidly rotating galaxy at z = 5.4}}, doi = {10.3847/2041-8213/ad7b17}, volume = {976}, year = {2024}, } @article{18761, abstract = {Termites, together with cockroaches, belong to the Blattodea. They possess an XX/XY sex determination system which has evolved from an XX/X0 system present in other Blattodean species, such as cockroaches and wood roaches. Little is currently known about the sex chromosomes of termites, their gene content, or their evolution. We here investigate the X chromosome of multiple termite species and compare them with the X chromosome of cockroaches using genomic and transcriptomic data. We find that the X chromosome of the termite Macrotermes natalensis is large and differentiated showing hall marks of sex chromosome evolution such as dosage compensation, while this does not seem to be the case in the other two termite species investigated here where sex chromosomes may be evolutionary younger. Furthermore, the X chromosome in M. natalensis is different from the X chromosome found in the cockroach Blattella germanica indicating that sex chromosome turn-over events may have happened during termite evolution.}, author = {Fraser, Roxanne and Moraa, Ruth and Djolai, Annika and Meisenheimer, Nils and Laube, Sophie and Vicoso, Beatriz and Huylmans, Ann K}, issn = {1759-6653}, journal = {Genome Biology and Evolution}, number = {12}, publisher = {Oxford University Press}, title = {{Evidence for a novel X chromosome in termites}}, doi = {10.1093/gbe/evae265}, volume = {16}, year = {2024}, }