---
_id: '7002'
abstract:
- lang: eng
  text: Multiple Importance Sampling (MIS) is a key technique for achieving robustness
    of Monte Carlo estimators in computer graphics and other fields. We derive optimal
    weighting functions for MIS that provably minimize the variance of an MIS estimator,
    given a set of sampling techniques. We show that the resulting variance reduction
    over the balance heuristic can be higher than predicted by the variance bounds
    derived by Veach and Guibas, who assumed only non-negative weights in their proof.
    We theoretically analyze the variance of the optimal MIS weights and show the
    relation to the variance of the balance heuristic. Furthermore, we establish a
    connection between the new weighting functions and control variates as previously
    applied to mixture sampling. We apply the new optimal weights to integration problems
    in light transport and show that they allow for new design considerations when
    choosing the appropriate sampling techniques for a given integration problem.
article_number: '37'
article_processing_charge: No
article_type: original
author:
- first_name: Ivo
  full_name: Kondapaneni, Ivo
  last_name: Kondapaneni
- first_name: Petr
  full_name: Vevoda, Petr
  last_name: Vevoda
- first_name: Pascal
  full_name: Grittmann, Pascal
  last_name: Grittmann
- first_name: Tomas
  full_name: Skrivan, Tomas
  id: 486A5A46-F248-11E8-B48F-1D18A9856A87
  last_name: Skrivan
- first_name: Philipp
  full_name: Slusallek, Philipp
  last_name: Slusallek
- first_name: Jaroslav
  full_name: Křivánek, Jaroslav
  last_name: Křivánek
citation:
  ama: Kondapaneni I, Vevoda P, Grittmann P, Skrivan T, Slusallek P, Křivánek J. Optimal
    multiple importance sampling. <i>ACM Transactions on Graphics</i>. 2019;38(4).
    doi:<a href="https://doi.org/10.1145/3306346.3323009">10.1145/3306346.3323009</a>
  apa: Kondapaneni, I., Vevoda, P., Grittmann, P., Skrivan, T., Slusallek, P., &#38;
    Křivánek, J. (2019). Optimal multiple importance sampling. <i>ACM Transactions
    on Graphics</i>. ACM. <a href="https://doi.org/10.1145/3306346.3323009">https://doi.org/10.1145/3306346.3323009</a>
  chicago: Kondapaneni, Ivo, Petr Vevoda, Pascal Grittmann, Tomas Skrivan, Philipp
    Slusallek, and Jaroslav Křivánek. “Optimal Multiple Importance Sampling.” <i>ACM
    Transactions on Graphics</i>. ACM, 2019. <a href="https://doi.org/10.1145/3306346.3323009">https://doi.org/10.1145/3306346.3323009</a>.
  ieee: I. Kondapaneni, P. Vevoda, P. Grittmann, T. Skrivan, P. Slusallek, and J.
    Křivánek, “Optimal multiple importance sampling,” <i>ACM Transactions on Graphics</i>,
    vol. 38, no. 4. ACM, 2019.
  ista: Kondapaneni I, Vevoda P, Grittmann P, Skrivan T, Slusallek P, Křivánek J.
    2019. Optimal multiple importance sampling. ACM Transactions on Graphics. 38(4),
    37.
  mla: Kondapaneni, Ivo, et al. “Optimal Multiple Importance Sampling.” <i>ACM Transactions
    on Graphics</i>, vol. 38, no. 4, 37, ACM, 2019, doi:<a href="https://doi.org/10.1145/3306346.3323009">10.1145/3306346.3323009</a>.
  short: I. Kondapaneni, P. Vevoda, P. Grittmann, T. Skrivan, P. Slusallek, J. Křivánek,
    ACM Transactions on Graphics 38 (2019).
date_created: 2019-11-12T13:05:40Z
date_published: 2019-07-01T00:00:00Z
date_updated: 2025-03-31T15:58:17Z
day: '01'
department:
- _id: ChWo
doi: 10.1145/3306346.3323009
ec_funded: 1
external_id:
  isi:
  - '000475740600011'
intvolume: '        38'
isi: 1
issue: '4'
language:
- iso: eng
month: '07'
oa_version: None
project:
- _id: 2508E324-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '642841'
  name: Distributed 3D Object Design
publication: ACM Transactions on Graphics
publication_identifier:
  issn:
  - 0730-0301
publication_status: published
publisher: ACM
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal multiple importance sampling
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 38
year: '2019'
...
---
_id: '7005'
abstract:
- lang: eng
  text: Activity-dependent bulk endocytosis generates synaptic vesicles (SVs) during
    intense neuronal activity via a two-step process. First, bulk endosomes are formed
    direct from the plasma membrane from which SVs are then generated. SV generation
    from bulk endosomes requires the efflux of previously accumulated calcium and
    activation of the protein phosphatase calcineurin. However, it is still unknown
    how calcineurin mediates SV generation. We addressed this question using a series
    of acute interventions that decoupled the generation of SVs from bulk endosomes
    in rat primary neuronal culture. This was achieved by either disruption of protein–protein
    interactions via delivery of competitive peptides, or inhibition of enzyme activity
    by known inhibitors. SV generation was monitored using either a morphological
    horseradish peroxidase assay or an optical assay that monitors the replenishment
    of the reserve SV pool. We found that SV generation was inhibited by, (i) peptides
    that disrupt calcineurin interactions, (ii) an inhibitor of dynamin I GTPase activity
    and (iii) peptides that disrupt the phosphorylation-dependent dynamin I–syndapin
    I interaction. Peptides that disrupted syndapin I interactions with eps15 homology
    domain-containing proteins had no effect. This revealed that (i) calcineurin must
    be localized at bulk endosomes to mediate its effect, (ii) dynamin I GTPase activity
    is essential for SV fission and (iii) the calcineurin-dependent interaction between
    dynamin I and syndapin I is essential for SV generation. We therefore propose
    that a calcineurin-dependent dephosphorylation cascade that requires both dynamin
    I GTPase and syndapin I lipid-deforming activity is essential for SV generation
    from bulk endosomes.
article_processing_charge: No
article_type: original
author:
- first_name: Giselle T
  full_name: Cheung, Giselle T
  id: 471195F6-F248-11E8-B48F-1D18A9856A87
  last_name: Cheung
  orcid: 0000-0001-8457-2572
- first_name: Michael A.
  full_name: Cousin, Michael A.
  last_name: Cousin
citation:
  ama: Cheung GT, Cousin MA. Synaptic vesicle generation from activity‐dependent bulk
    endosomes requires a dephosphorylation‐dependent dynamin–syndapin interaction.
    <i>Journal of Neurochemistry</i>. 2019;151(5):570-583. doi:<a href="https://doi.org/10.1111/jnc.14862">10.1111/jnc.14862</a>
  apa: Cheung, G. T., &#38; Cousin, M. A. (2019). Synaptic vesicle generation from
    activity‐dependent bulk endosomes requires a dephosphorylation‐dependent dynamin–syndapin
    interaction. <i>Journal of Neurochemistry</i>. Wiley. <a href="https://doi.org/10.1111/jnc.14862">https://doi.org/10.1111/jnc.14862</a>
  chicago: Cheung, Giselle T, and Michael A. Cousin. “Synaptic Vesicle Generation
    from Activity‐dependent Bulk Endosomes Requires a Dephosphorylation‐dependent
    Dynamin–Syndapin Interaction.” <i>Journal of Neurochemistry</i>. Wiley, 2019.
    <a href="https://doi.org/10.1111/jnc.14862">https://doi.org/10.1111/jnc.14862</a>.
  ieee: G. T. Cheung and M. A. Cousin, “Synaptic vesicle generation from activity‐dependent
    bulk endosomes requires a dephosphorylation‐dependent dynamin–syndapin interaction,”
    <i>Journal of Neurochemistry</i>, vol. 151, no. 5. Wiley, pp. 570–583, 2019.
  ista: Cheung GT, Cousin MA. 2019. Synaptic vesicle generation from activity‐dependent
    bulk endosomes requires a dephosphorylation‐dependent dynamin–syndapin interaction.
    Journal of Neurochemistry. 151(5), 570–583.
  mla: Cheung, Giselle T., and Michael A. Cousin. “Synaptic Vesicle Generation from
    Activity‐dependent Bulk Endosomes Requires a Dephosphorylation‐dependent Dynamin–Syndapin
    Interaction.” <i>Journal of Neurochemistry</i>, vol. 151, no. 5, Wiley, 2019,
    pp. 570–83, doi:<a href="https://doi.org/10.1111/jnc.14862">10.1111/jnc.14862</a>.
  short: G.T. Cheung, M.A. Cousin, Journal of Neurochemistry 151 (2019) 570–583.
date_created: 2019-11-12T14:37:08Z
date_published: 2019-12-01T00:00:00Z
date_updated: 2023-08-30T07:21:50Z
day: '01'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1111/jnc.14862
external_id:
  isi:
  - '000490703100001'
  pmid:
  - '31479508'
file:
- access_level: open_access
  checksum: ec1fb2aebb874009bc309adaada6e1d7
  content_type: application/pdf
  creator: dernst
  date_created: 2020-02-05T10:30:02Z
  date_updated: 2020-07-14T12:47:47Z
  file_id: '7452'
  file_name: 2019_JournNeurochemistry_Cheung.pdf
  file_size: 4334962
  relation: main_file
file_date_updated: 2020-07-14T12:47:47Z
has_accepted_license: '1'
intvolume: '       151'
isi: 1
issue: '5'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: 570-583
pmid: 1
publication: Journal of Neurochemistry
publication_identifier:
  eissn:
  - 1471-4159
  issn:
  - 0022-3042
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synaptic vesicle generation from activity‐dependent bulk endosomes requires
  a dephosphorylation‐dependent dynamin–syndapin interaction
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 151
year: '2019'
...
---
_id: '7007'
abstract:
- lang: eng
  text: 'We consider the primitive relay channel, where the source sends a message
    to the relay and to the destination, and the relay helps the communication by
    transmitting an additional message to the destination via a separate channel.
    Two well-known coding techniques have been introduced for this setting: decode-and-forward
    and compress-and-forward. In decode-and-forward, the relay completely decodes
    the message and sends some information to the destination; in compress-and-forward,
    the relay does not decode, and it sends a compressed version of the received signal
    to the destination using Wyner–Ziv coding. In this paper, we present a novel coding
    paradigm that provides an improved achievable rate for the primitive relay channel.
    The idea is to combine compress-and-forward and decode-and-forward via a chaining
    construction. We transmit over pairs of blocks: in the first block, we use compress-and-forward;
    and, in the second block, we use decode-and-forward. More specifically, in the
    first block, the relay does not decode, it compresses the received signal via
    Wyner–Ziv, and it sends only part of the compression to the destination. In the
    second block, the relay completely decodes the message, it sends some information
    to the destination, and it also sends the remaining part of the compression coming
    from the first block. By doing so, we are able to strictly outperform both compress-and-forward
    and decode-and-forward. Note that the proposed coding scheme can be implemented
    with polar codes. As such, it has the typical attractive properties of polar coding
    schemes, namely, quasi-linear encoding and decoding complexity, and error probability
    that decays at super-polynomial speed. As a running example, we take into account
    the special case of the erasure relay channel, and we provide a comparison between
    the rates achievable by our proposed scheme and the existing upper and lower bounds.'
article_number: '218'
article_type: original
arxiv: 1
author:
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: S. Hamed
  full_name: Hassani, S. Hamed
  last_name: Hassani
- first_name: Rüdiger
  full_name: Urbanke, Rüdiger
  last_name: Urbanke
citation:
  ama: Mondelli M, Hassani SH, Urbanke R. A new coding paradigm for the primitive
    relay channel. <i>Algorithms</i>. 2019;12(10). doi:<a href="https://doi.org/10.3390/a12100218">10.3390/a12100218</a>
  apa: Mondelli, M., Hassani, S. H., &#38; Urbanke, R. (2019). A new coding paradigm
    for the primitive relay channel. <i>Algorithms</i>. MDPI. <a href="https://doi.org/10.3390/a12100218">https://doi.org/10.3390/a12100218</a>
  chicago: Mondelli, Marco, S. Hamed Hassani, and Rüdiger Urbanke. “A New Coding Paradigm
    for the Primitive Relay Channel.” <i>Algorithms</i>. MDPI, 2019. <a href="https://doi.org/10.3390/a12100218">https://doi.org/10.3390/a12100218</a>.
  ieee: M. Mondelli, S. H. Hassani, and R. Urbanke, “A new coding paradigm for the
    primitive relay channel,” <i>Algorithms</i>, vol. 12, no. 10. MDPI, 2019.
  ista: Mondelli M, Hassani SH, Urbanke R. 2019. A new coding paradigm for the primitive
    relay channel. Algorithms. 12(10), 218.
  mla: Mondelli, Marco, et al. “A New Coding Paradigm for the Primitive Relay Channel.”
    <i>Algorithms</i>, vol. 12, no. 10, 218, MDPI, 2019, doi:<a href="https://doi.org/10.3390/a12100218">10.3390/a12100218</a>.
  short: M. Mondelli, S.H. Hassani, R. Urbanke, Algorithms 12 (2019).
corr_author: '1'
date_created: 2019-11-12T14:46:19Z
date_published: 2019-10-18T00:00:00Z
date_updated: 2024-10-09T20:59:05Z
day: '18'
ddc:
- '510'
department:
- _id: MaMo
doi: 10.3390/a12100218
external_id:
  arxiv:
  - '1801.03153'
file:
- access_level: open_access
  checksum: 267756d8f9db572f496cd1663c89d59a
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-12T14:48:45Z
  date_updated: 2020-07-14T12:47:47Z
  file_id: '7008'
  file_name: 2019_Algorithms_Mondelli.pdf
  file_size: 696791
  relation: main_file
file_date_updated: 2020-07-14T12:47:47Z
has_accepted_license: '1'
intvolume: '        12'
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: Algorithms
publication_identifier:
  issn:
  - 1999-4893
publication_status: published
publisher: MDPI
quality_controlled: '1'
related_material:
  record:
  - id: '6675'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: A new coding paradigm for the primitive relay channel
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2019'
...
---
_id: '7009'
abstract:
- lang: eng
  text: Cell migration is essential for physiological processes as diverse as development,
    immune defence and wound healing. It is also a hallmark of cancer malignancy.
    Thousands of publications have elucidated detailed molecular and biophysical mechanisms
    of cultured cells migrating on flat, 2D substrates of glass and plastic. However,
    much less is known about how cells successfully navigate the complex 3D environments
    of living tissues. In these more complex, native environments, cells use multiple
    modes of migration, including mesenchymal, amoeboid, lobopodial and collective,
    and these are governed by the local extracellular microenvironment, specific modalities
    of Rho GTPase signalling and non- muscle myosin contractility. Migration through
    3D environments is challenging because it requires the cell to squeeze through
    complex or dense extracellular structures. Doing so requires specific cellular
    adaptations to mechanical features of the extracellular matrix (ECM) or its remodelling.
    In addition, besides navigating through diverse ECM environments and overcoming
    extracellular barriers, cells often interact with neighbouring cells and tissues
    through physical and signalling interactions. Accordingly, cells need to call
    on an impressively wide diversity of mechanisms to meet these challenges. This
    Review examines how cells use both classical and novel mechanisms of locomotion
    as they traverse challenging 3D matrices and cellular environments. It focuses
    on principles rather than details of migratory mechanisms and draws comparisons
    between 1D, 2D and 3D migration.
article_processing_charge: No
article_type: review
author:
- first_name: KM
  full_name: Yamada, KM
  last_name: Yamada
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Yamada K, Sixt MK. Mechanisms of 3D cell migration. <i>Nature Reviews Molecular
    Cell Biology</i>. 2019;20(12):738–752. doi:<a href="https://doi.org/10.1038/s41580-019-0172-9">10.1038/s41580-019-0172-9</a>
  apa: Yamada, K., &#38; Sixt, M. K. (2019). Mechanisms of 3D cell migration. <i>Nature
    Reviews Molecular Cell Biology</i>. Springer Nature. <a href="https://doi.org/10.1038/s41580-019-0172-9">https://doi.org/10.1038/s41580-019-0172-9</a>
  chicago: Yamada, KM, and Michael K Sixt. “Mechanisms of 3D Cell Migration.” <i>Nature
    Reviews Molecular Cell Biology</i>. Springer Nature, 2019. <a href="https://doi.org/10.1038/s41580-019-0172-9">https://doi.org/10.1038/s41580-019-0172-9</a>.
  ieee: K. Yamada and M. K. Sixt, “Mechanisms of 3D cell migration,” <i>Nature Reviews
    Molecular Cell Biology</i>, vol. 20, no. 12. Springer Nature, pp. 738–752, 2019.
  ista: Yamada K, Sixt MK. 2019. Mechanisms of 3D cell migration. Nature Reviews Molecular
    Cell Biology. 20(12), 738–752.
  mla: Yamada, KM, and Michael K. Sixt. “Mechanisms of 3D Cell Migration.” <i>Nature
    Reviews Molecular Cell Biology</i>, vol. 20, no. 12, Springer Nature, 2019, pp.
    738–752, doi:<a href="https://doi.org/10.1038/s41580-019-0172-9">10.1038/s41580-019-0172-9</a>.
  short: K. Yamada, M.K. Sixt, Nature Reviews Molecular Cell Biology 20 (2019) 738–752.
date_created: 2019-11-12T14:54:42Z
date_published: 2019-12-01T00:00:00Z
date_updated: 2023-08-30T07:22:20Z
day: '01'
department:
- _id: MiSi
doi: 10.1038/s41580-019-0172-9
external_id:
  isi:
  - '000497966900007'
  pmid:
  - '31582855'
intvolume: '        20'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 738–752
pmid: 1
publication: Nature Reviews Molecular Cell Biology
publication_identifier:
  eissn:
  - 1471-0080
  issn:
  - 1471-0072
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanisms of 3D cell migration
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 20
year: '2019'
...
---
_id: '7010'
abstract:
- lang: eng
  text: Numerous biophysical questions require the quantification of short-range interactions
    between (functionalized) surfaces and synthetic or biological objects such as
    cells. Here, we present an original, custom built setup for reflection interference
    contrast microscopy that can assess distances between a substrate and a flowing
    object at high speed with nanometric accuracy. We demonstrate its use to decipher
    the complex biochemical and mechanical interplay regulating blood cell homing
    at the vessel wall in the microcirculation using an in vitro approach. We show
    that in the absence of specific biochemical interactions, flowing cells are repelled
    from the soft layer lining the vessel wall, contributing to red blood cell repulsion
    in vivo. In contrast, this so-called glycocalyx stabilizes rolling of cells under
    flow in the presence of a specific receptor naturally present on activated leucocytes
    and a number of cancer cell lines.
article_number: 110760V
article_processing_charge: No
author:
- first_name: Heather S.
  full_name: Davies, Heather S.
  last_name: Davies
- first_name: Natalia S.
  full_name: Baranova, Natalia S.
  id: 38661662-F248-11E8-B48F-1D18A9856A87
  last_name: Baranova
  orcid: 0000-0002-3086-9124
- first_name: Nouha
  full_name: El Amri, Nouha
  last_name: El Amri
- first_name: Liliane
  full_name: Coche-Guérente, Liliane
  last_name: Coche-Guérente
- first_name: Claude
  full_name: Verdier, Claude
  last_name: Verdier
- first_name: Lionel
  full_name: Bureau, Lionel
  last_name: Bureau
- first_name: Ralf P.
  full_name: Richter, Ralf P.
  last_name: Richter
- first_name: Delphine
  full_name: Débarre, Delphine
  last_name: Débarre
citation:
  ama: 'Davies HS, Baranova NS, El Amri N, et al. Blood cell-vessel wall interactions
    probed by reflection interference contrast microscopy. In: <i>Advances in Microscopic
    Imaging II</i>. Vol 11076. SPIE; 2019. doi:<a href="https://doi.org/10.1117/12.2527058">10.1117/12.2527058</a>'
  apa: 'Davies, H. S., Baranova, N. S., El Amri, N., Coche-Guérente, L., Verdier,
    C., Bureau, L., … Débarre, D. (2019). Blood cell-vessel wall interactions probed
    by reflection interference contrast microscopy. In <i>Advances in Microscopic
    Imaging II</i> (Vol. 11076). Munich, Germany: SPIE. <a href="https://doi.org/10.1117/12.2527058">https://doi.org/10.1117/12.2527058</a>'
  chicago: Davies, Heather S., Natalia S. Baranova, Nouha El Amri, Liliane Coche-Guérente,
    Claude Verdier, Lionel Bureau, Ralf P. Richter, and Delphine Débarre. “Blood Cell-Vessel
    Wall Interactions Probed by Reflection Interference Contrast Microscopy.” In <i>Advances
    in Microscopic Imaging II</i>, Vol. 11076. SPIE, 2019. <a href="https://doi.org/10.1117/12.2527058">https://doi.org/10.1117/12.2527058</a>.
  ieee: H. S. Davies <i>et al.</i>, “Blood cell-vessel wall interactions probed by
    reflection interference contrast microscopy,” in <i>Advances in Microscopic Imaging
    II</i>, Munich, Germany, 2019, vol. 11076.
  ista: Davies HS, Baranova NS, El Amri N, Coche-Guérente L, Verdier C, Bureau L,
    Richter RP, Débarre D. 2019. Blood cell-vessel wall interactions probed by reflection
    interference contrast microscopy. Advances in Microscopic Imaging II. European
    Conferences on Biomedical Optics vol. 11076, 110760V.
  mla: Davies, Heather S., et al. “Blood Cell-Vessel Wall Interactions Probed by Reflection
    Interference Contrast Microscopy.” <i>Advances in Microscopic Imaging II</i>,
    vol. 11076, 110760V, SPIE, 2019, doi:<a href="https://doi.org/10.1117/12.2527058">10.1117/12.2527058</a>.
  short: H.S. Davies, N.S. Baranova, N. El Amri, L. Coche-Guérente, C. Verdier, L.
    Bureau, R.P. Richter, D. Débarre, in:, Advances in Microscopic Imaging II, SPIE,
    2019.
conference:
  end_date: 2019-06-27
  location: Munich, Germany
  name: European Conferences on Biomedical Optics
  start_date: 2019-06-26
date_created: 2019-11-12T15:10:18Z
date_published: 2019-07-22T00:00:00Z
date_updated: 2023-08-29T06:54:38Z
day: '22'
department:
- _id: MaLo
doi: 10.1117/12.2527058
external_id:
  isi:
  - '000535353000023'
intvolume: '     11076'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://hal.archives-ouvertes.fr/hal-02368135/file/110760V.pdf
month: '07'
oa: 1
oa_version: Published Version
publication: Advances in Microscopic Imaging II
publication_identifier:
  isbn:
  - '9781510628458'
  issn:
  - 1605-7422
publication_status: published
publisher: SPIE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Blood cell-vessel wall interactions probed by reflection interference contrast
  microscopy
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11076
year: '2019'
...
---
_id: '7013'
abstract:
- lang: eng
  text: Chains of superconducting circuit devices provide a natural platform for studies
    of synthetic bosonic quantum matter. Motivated by the recent experimental progress
    in realizing disordered and interacting chains of superconducting transmon devices,
    we study the bosonic many-body localization phase transition using the methods
    of exact diagonalization as well as matrix product state dynamics. We estimate
    the location of transition separating the ergodic and the many-body localized
    phases as a function of the disorder strength and the many-body on-site interaction
    strength. The main difference between the bosonic model realized by superconducting
    circuits and similar fermionic model is that the effect of the on-site interaction
    is stronger due to the possibility of multiple excitations occupying the same
    site. The phase transition is found to be robust upon including longer-range hopping
    and interaction terms present in the experiments. Furthermore, we calculate experimentally
    relevant local observables and show that their temporal fluctuations can be used
    to distinguish between the dynamics of Anderson insulator, many-body localization,
    and delocalized phases. While we consider unitary dynamics, neglecting the effects
    of dissipation, decoherence, and measurement back action, the timescales on which
    the dynamics is unitary are sufficient for observation of characteristic dynamics
    in the many-body localized phase. Moreover, the experimentally available disorder
    strength and interactions allow for tuning the many-body localization phase transition,
    thus making the arrays of superconducting circuit devices a promising platform
    for exploring localization physics and phase transition.
article_number: '134504'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Tuure
  full_name: Orell, Tuure
  last_name: Orell
- first_name: Alexios
  full_name: Michailidis, Alexios
  id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
  last_name: Michailidis
  orcid: 0000-0002-8443-1064
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
- first_name: Matti
  full_name: Silveri, Matti
  last_name: Silveri
citation:
  ama: Orell T, Michailidis A, Serbyn M, Silveri M. Probing the many-body localization
    phase transition with superconducting circuits. <i>Physical Review B</i>. 2019;100(13).
    doi:<a href="https://doi.org/10.1103/physrevb.100.134504">10.1103/physrevb.100.134504</a>
  apa: Orell, T., Michailidis, A., Serbyn, M., &#38; Silveri, M. (2019). Probing the
    many-body localization phase transition with superconducting circuits. <i>Physical
    Review B</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevb.100.134504">https://doi.org/10.1103/physrevb.100.134504</a>
  chicago: Orell, Tuure, Alexios Michailidis, Maksym Serbyn, and Matti Silveri. “Probing
    the Many-Body Localization Phase Transition with Superconducting Circuits.” <i>Physical
    Review B</i>. American Physical Society, 2019. <a href="https://doi.org/10.1103/physrevb.100.134504">https://doi.org/10.1103/physrevb.100.134504</a>.
  ieee: T. Orell, A. Michailidis, M. Serbyn, and M. Silveri, “Probing the many-body
    localization phase transition with superconducting circuits,” <i>Physical Review
    B</i>, vol. 100, no. 13. American Physical Society, 2019.
  ista: Orell T, Michailidis A, Serbyn M, Silveri M. 2019. Probing the many-body localization
    phase transition with superconducting circuits. Physical Review B. 100(13), 134504.
  mla: Orell, Tuure, et al. “Probing the Many-Body Localization Phase Transition with
    Superconducting Circuits.” <i>Physical Review B</i>, vol. 100, no. 13, 134504,
    American Physical Society, 2019, doi:<a href="https://doi.org/10.1103/physrevb.100.134504">10.1103/physrevb.100.134504</a>.
  short: T. Orell, A. Michailidis, M. Serbyn, M. Silveri, Physical Review B 100 (2019).
date_created: 2019-11-13T08:25:48Z
date_published: 2019-10-01T00:00:00Z
date_updated: 2024-02-28T13:13:13Z
day: '01'
department:
- _id: MaSe
doi: 10.1103/physrevb.100.134504
external_id:
  arxiv:
  - '1907.04043'
  isi:
  - '000489036500004'
intvolume: '       100'
isi: 1
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1907.04043
month: '10'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Probing the many-body localization phase transition with superconducting circuits
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 100
year: '2019'
...
---
_id: '7015'
abstract:
- lang: eng
  text: We modify the "floating crystal" trial state for the classical homogeneous
    electron gas (also known as jellium), in order to suppress the boundary charge
    fluctuations that are known to lead to a macroscopic increase of the energy. The
    argument is to melt a thin layer of the crystal close to the boundary and consequently
    replace it by an incompressible fluid. With the aid of this trial state we show
    that three different definitions of the ground-state energy of jellium coincide.
    In the first point of view the electrons are placed in a neutralizing uniform
    background. In the second definition there is no background but the electrons
    are submitted to the constraint that their density is constant, as is appropriate
    in density functional theory. Finally, in the third system each electron interacts
    with a periodic image of itself; that is, periodic boundary conditions are imposed
    on the interaction potential.
article_number: '035127'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Mathieu
  full_name: Lewin, Mathieu
  last_name: Lewin
- first_name: Elliott H.
  full_name: Lieb, Elliott H.
  last_name: Lieb
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Lewin M, Lieb EH, Seiringer R. Floating Wigner crystal with no boundary charge
    fluctuations. <i>Physical Review B</i>. 2019;100(3). doi:<a href="https://doi.org/10.1103/physrevb.100.035127">10.1103/physrevb.100.035127</a>
  apa: Lewin, M., Lieb, E. H., &#38; Seiringer, R. (2019). Floating Wigner crystal
    with no boundary charge fluctuations. <i>Physical Review B</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevb.100.035127">https://doi.org/10.1103/physrevb.100.035127</a>
  chicago: Lewin, Mathieu, Elliott H. Lieb, and Robert Seiringer. “Floating Wigner
    Crystal with No Boundary Charge Fluctuations.” <i>Physical Review B</i>. American
    Physical Society, 2019. <a href="https://doi.org/10.1103/physrevb.100.035127">https://doi.org/10.1103/physrevb.100.035127</a>.
  ieee: M. Lewin, E. H. Lieb, and R. Seiringer, “Floating Wigner crystal with no boundary
    charge fluctuations,” <i>Physical Review B</i>, vol. 100, no. 3. American Physical
    Society, 2019.
  ista: Lewin M, Lieb EH, Seiringer R. 2019. Floating Wigner crystal with no boundary
    charge fluctuations. Physical Review B. 100(3), 035127.
  mla: Lewin, Mathieu, et al. “Floating Wigner Crystal with No Boundary Charge Fluctuations.”
    <i>Physical Review B</i>, vol. 100, no. 3, 035127, American Physical Society,
    2019, doi:<a href="https://doi.org/10.1103/physrevb.100.035127">10.1103/physrevb.100.035127</a>.
  short: M. Lewin, E.H. Lieb, R. Seiringer, Physical Review B 100 (2019).
date_created: 2019-11-13T08:41:48Z
date_published: 2019-07-25T00:00:00Z
date_updated: 2025-04-14T07:27:00Z
day: '25'
department:
- _id: RoSe
doi: 10.1103/physrevb.100.035127
ec_funded: 1
external_id:
  arxiv:
  - '1905.09138'
  isi:
  - '000477888200001'
intvolume: '       100'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1905.09138
month: '07'
oa: 1
oa_version: Preprint
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Floating Wigner crystal with no boundary charge fluctuations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 100
year: '2019'
...
---
_id: '7016'
abstract:
- lang: eng
  text: Organisms cope with change by employing transcriptional regulators. However,
    when faced with rare environments, the evolution of transcriptional regulators
    and their promoters may be too slow. We ask whether the intrinsic instability
    of gene duplication and amplification provides a generic alternative to canonical
    gene regulation. By real-time monitoring of gene copy number mutations in E. coli,
    we show that gene duplications and amplifications enable adaptation to fluctuating
    environments by rapidly generating copy number, and hence expression level, polymorphism.
    This ‘amplification-mediated gene expression tuning’ occurs on timescales similar
    to canonical gene regulation and can deal with rapid environmental changes. Mathematical
    modeling shows that amplifications also tune gene expression in stochastic environments
    where transcription factor-based schemes are hard to evolve or maintain. The fleeting
    nature of gene amplifications gives rise to a generic population-level mechanism
    that relies on genetic heterogeneity to rapidly tune expression of any gene, without
    leaving any genomic signature.
article_processing_charge: No
author:
- first_name: Isabella
  full_name: Tomanek, Isabella
  id: 3981F020-F248-11E8-B48F-1D18A9856A87
  last_name: Tomanek
  orcid: 0000-0001-6197-363X
citation:
  ama: Tomanek I. Data for the paper “Gene amplification as a form of population-level
    gene expression regulation.” 2019. doi:<a href="https://doi.org/10.15479/AT:ISTA:7016">10.15479/AT:ISTA:7016</a>
  apa: Tomanek, I. (2019). Data for the paper “Gene amplification as a form of population-level
    gene expression regulation.” Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:7016">https://doi.org/10.15479/AT:ISTA:7016</a>
  chicago: Tomanek, Isabella. “Data for the Paper ‘Gene Amplification as a Form of
    Population-Level Gene Expression Regulation.’” Institute of Science and Technology
    Austria, 2019. <a href="https://doi.org/10.15479/AT:ISTA:7016">https://doi.org/10.15479/AT:ISTA:7016</a>.
  ieee: I. Tomanek, “Data for the paper ‘Gene amplification as a form of population-level
    gene expression regulation.’” Institute of Science and Technology Austria, 2019.
  ista: Tomanek I. 2019. Data for the paper ‘Gene amplification as a form of population-level
    gene expression regulation’, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:7016">10.15479/AT:ISTA:7016</a>.
  mla: Tomanek, Isabella. <i>Data for the Paper “Gene Amplification as a Form of Population-Level
    Gene Expression Regulation.”</i> Institute of Science and Technology Austria,
    2019, doi:<a href="https://doi.org/10.15479/AT:ISTA:7016">10.15479/AT:ISTA:7016</a>.
  short: I. Tomanek, (2019).
contributor:
- contributor_type: project_leader
  first_name: Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
date_created: 2019-11-13T09:07:31Z
date_published: 2019-11-13T00:00:00Z
date_updated: 2025-06-12T07:34:12Z
day: '13'
ddc:
- '576'
department:
- _id: CaGu
doi: 10.15479/AT:ISTA:7016
file:
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  checksum: 72441055043eda4cbf1398a422e2c118
  content_type: application/octet-stream
  creator: itomanek
  date_created: 2019-11-13T08:52:21Z
  date_updated: 2020-07-14T12:47:47Z
  description: Illumina whole genome sequence data for Locus 1 - amplified.
  file_id: '7017'
  file_name: D8_S35_R2_001.fastq
  file_size: 2456192500
  relation: main_file
  title: Locus1_amplified
- access_level: open_access
  checksum: a4ac50bf655d9c751f0305ade5c2ee16
  content_type: application/octet-stream
  creator: itomanek
  date_created: 2019-11-13T08:52:59Z
  date_updated: 2020-07-14T12:47:47Z
  description: Illumina whole genome sequence data for Locus 1 - ancestral.
  file_id: '7018'
  file_name: IT028_S11_R2_001.fastq
  file_size: 2833452234
  relation: main_file
  title: Locus1_ancestral
- access_level: open_access
  checksum: 5b227708ff478ca06e3f0448a4efdc2f
  content_type: application/octet-stream
  creator: itomanek
  date_created: 2019-11-13T08:54:10Z
  date_updated: 2020-07-14T12:47:47Z
  description: Illumina whole genome sequence data for Locus 1 - amplified, after
    DOG-selection.
  file_id: '7019'
  file_name: D8-DOG1_S47_R2_001.fastq
  file_size: 2878017264
  relation: main_file
  title: Locus1_amplified_DOG
- access_level: open_access
  checksum: d9550a4c044116075fa83f8f2ea31d6f
  content_type: application/octet-stream
  creator: itomanek
  date_created: 2019-11-13T08:54:27Z
  date_updated: 2020-07-14T12:47:47Z
  description: Illumina whole genome sequence data for Locus 2 - amplified.
  file_id: '7020'
  file_name: D4_S71_R2_001.fastq
  file_size: 2180826995
  relation: main_file
  title: Locus2_amplified
- access_level: open_access
  checksum: 466ceb302c020ac013007a879fcde69d
  content_type: application/octet-stream
  creator: itomanek
  date_created: 2019-11-13T08:55:58Z
  date_updated: 2020-07-14T12:47:47Z
  description: Illumina whole genome sequence data for Locus 2 - ancestral.
  file_id: '7021'
  file_name: IT030_S23_R2_001.fastq
  file_size: 2108826444
  relation: main_file
  title: Locus2_ancestral
- access_level: open_access
  checksum: 8aeb1da771713c7baa5a847eff889604
  content_type: application/octet-stream
  creator: itomanek
  date_created: 2019-11-21T12:31:01Z
  date_updated: 2020-07-14T12:47:47Z
  description: Illumina whole genome sequence data for Locus 2 - amplified, after
    DOG-selection.
  file_id: '7092'
  file_name: D4-DOG1_S83_R2_001.fastq
  file_size: 3144330494
  relation: main_file
  title: Locus2_amplified_DOG
- access_level: open_access
  checksum: bf7d4b053f14af4655fb5574209fdb2d
  content_type: application/zip
  creator: itomanek
  date_created: 2020-01-14T11:22:27Z
  date_updated: 2020-07-14T12:47:47Z
  description: Compressed genbank file format containing the sequence of the chromosomal
    reporter gene cassette.
  file_id: '7273'
  file_name: galK_dual_reporter_cassette.gb.zip
  file_size: 4179
  relation: main_file
  title: DNA sequence of the chromosomal reporter gene cassette
- access_level: open_access
  checksum: 5e91cee2eff6f4a7cde456c6fb07c2ff
  content_type: text/plain
  creator: dernst
  date_created: 2020-01-15T14:15:55Z
  date_updated: 2020-07-14T12:47:47Z
  file_id: '7335'
  file_name: Readme_7016.txt
  file_size: 435
  relation: main_file
  title: Read_me_sequence_data
- access_level: open_access
  checksum: 5e6745dcfb9c1b11dd935ac3ee45fe33
  content_type: application/zip
  creator: itomanek
  date_created: 2020-01-22T15:44:16Z
  date_updated: 2020-07-14T12:47:47Z
  description: FACS data associated with Fig. 2c - see read_me_FACS
  file_id: '7351'
  file_name: FACS_data.xlsx.zip
  file_size: 3765861
  relation: main_file
  title: FACS data
- access_level: open_access
  checksum: a85caf092ae4b17668f70af2d93fad00
  content_type: text/rtf
  creator: itomanek
  date_created: 2020-01-22T15:44:16Z
  date_updated: 2020-07-14T12:47:47Z
  file_id: '7352'
  file_name: read_me_FACS.rtf
  file_size: 4996
  relation: main_file
- access_level: open_access
  checksum: fd8ba5d75d24e47ddf7e70bfdadb40d4
  content_type: text/rtf
  creator: itomanek
  date_created: 2020-01-22T15:44:16Z
  date_updated: 2020-07-14T12:47:47Z
  file_id: '7353'
  file_name: read_me_microfluidics.rtf
  file_size: 868
  relation: main_file
- access_level: open_access
  checksum: 69c5dc5ca5c069a138183c934acc1778
  content_type: application/zip
  creator: itomanek
  date_created: 2020-01-22T15:44:17Z
  date_updated: 2020-07-14T12:47:47Z
  description: microfluidics time trace data - see read_me_microfluidics
  file_id: '7354'
  file_name: microfuidics_data.zip
  file_size: 8141727
  relation: main_file
  title: microfluidics data
file_date_updated: 2020-07-14T12:47:47Z
has_accepted_license: '1'
keyword:
- Escherichia coli
- gene amplification
- galactose
- DOG
- experimental evolution
- Illumina sequence data
- FACS data
- microfluidics data
month: '11'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '7652'
    relation: used_in_publication
    status: public
status: public
title: Data for the paper "Gene amplification as a form of population-level gene expression
  regulation"
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '7026'
abstract:
- lang: eng
  text: Effective design of combination therapies requires understanding the changes
    in cell physiology that result from drug interactions. Here, we show that the
    genome-wide transcriptional response to combinations of two drugs, measured at
    a rigorously controlled growth rate, can predict higher-order antagonism with
    a third drug in Saccharomyces cerevisiae. Using isogrowth profiling, over 90%
    of the variation in cellular response can be decomposed into three principal components
    (PCs) that have clear biological interpretations. We demonstrate that the third
    PC captures emergent transcriptional programs that are dependent on both drugs
    and can predict antagonism with a third drug targeting the emergent pathway. We
    further show that emergent gene expression patterns are most pronounced at a drug
    ratio where the drug interaction is strongest, providing a guideline for future
    measurements. Our results provide a readily applicable recipe for uncovering emergent
    responses in other systems and for higher-order drug combinations. A record of
    this paper’s transparent peer review process is included in the Supplemental Information.
acknowledged_ssus:
- _id: LifeSc
article_processing_charge: No
article_type: original
author:
- first_name: Martin
  full_name: Lukacisin, Martin
  id: 298FFE8C-F248-11E8-B48F-1D18A9856A87
  last_name: Lukacisin
  orcid: 0000-0001-6549-4177
- first_name: Tobias
  full_name: Bollenbach, Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
citation:
  ama: Lukacisin M, Bollenbach MT. Emergent gene expression responses to drug combinations
    predict higher-order drug interactions. <i>Cell Systems</i>. 2019;9(5):423-433.e1-e3.
    doi:<a href="https://doi.org/10.1016/j.cels.2019.10.004">10.1016/j.cels.2019.10.004</a>
  apa: Lukacisin, M., &#38; Bollenbach, M. T. (2019). Emergent gene expression responses
    to drug combinations predict higher-order drug interactions. <i>Cell Systems</i>.
    Cell Press. <a href="https://doi.org/10.1016/j.cels.2019.10.004">https://doi.org/10.1016/j.cels.2019.10.004</a>
  chicago: Lukacisin, Martin, and Mark Tobias Bollenbach. “Emergent Gene Expression
    Responses to Drug Combinations Predict Higher-Order Drug Interactions.” <i>Cell
    Systems</i>. Cell Press, 2019. <a href="https://doi.org/10.1016/j.cels.2019.10.004">https://doi.org/10.1016/j.cels.2019.10.004</a>.
  ieee: M. Lukacisin and M. T. Bollenbach, “Emergent gene expression responses to
    drug combinations predict higher-order drug interactions,” <i>Cell Systems</i>,
    vol. 9, no. 5. Cell Press, pp. 423-433.e1-e3, 2019.
  ista: Lukacisin M, Bollenbach MT. 2019. Emergent gene expression responses to drug
    combinations predict higher-order drug interactions. Cell Systems. 9(5), 423-433.e1-e3.
  mla: Lukacisin, Martin, and Mark Tobias Bollenbach. “Emergent Gene Expression Responses
    to Drug Combinations Predict Higher-Order Drug Interactions.” <i>Cell Systems</i>,
    vol. 9, no. 5, Cell Press, 2019, pp. 423-433.e1-e3, doi:<a href="https://doi.org/10.1016/j.cels.2019.10.004">10.1016/j.cels.2019.10.004</a>.
  short: M. Lukacisin, M.T. Bollenbach, Cell Systems 9 (2019) 423-433.e1-e3.
date_created: 2019-11-15T10:51:42Z
date_published: 2019-11-27T00:00:00Z
date_updated: 2025-04-15T08:09:37Z
day: '27'
ddc:
- '570'
department:
- _id: ToBo
doi: 10.1016/j.cels.2019.10.004
external_id:
  isi:
  - '000499495400003'
file:
- access_level: open_access
  checksum: 7a11d6c2f9523d65b049512d61733178
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-15T10:57:42Z
  date_updated: 2020-07-14T12:47:48Z
  file_id: '7027'
  file_name: 2019_CellSystems_Lukacisin.pdf
  file_size: 4238460
  relation: main_file
file_date_updated: 2020-07-14T12:47:48Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
issue: '5'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 423-433.e1-e3
project:
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27201-B22
  name: Revealing the mechanisms underlying drug interactions
- _id: 25EB3A80-B435-11E9-9278-68D0E5697425
  grant_number: RGP0042/2013
  name: Revealing the fundamental limits of cell growth
publication: Cell Systems
publication_identifier:
  issn:
  - 2405-4712
publication_status: published
publisher: Cell Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Emergent gene expression responses to drug combinations predict higher-order
  drug interactions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2019'
...
---
_id: '7032'
abstract:
- lang: eng
  text: Optical frequency combs (OFCs) are light sources whose spectra consists of
    equally spaced frequency lines in the optical domain [1]. They have great potential
    for improving high-capacity data transfer, all-optical atomic clocks, spectroscopy,
    and high-precision measurements [2].
article_number: '8873300'
article_processing_charge: No
author:
- first_name: Alfredo R
  full_name: Rueda Sanchez, Alfredo R
  id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
  last_name: Rueda Sanchez
  orcid: 0000-0001-6249-5860
- first_name: Florian
  full_name: Sedlmeir, Florian
  last_name: Sedlmeir
- first_name: Gerd
  full_name: Leuchs, Gerd
  last_name: Leuchs
- first_name: Madhuri
  full_name: Kuamri, Madhuri
  last_name: Kuamri
- first_name: Harald G. L.
  full_name: Schwefel, Harald G. L.
  last_name: Schwefel
citation:
  ama: 'Rueda Sanchez AR, Sedlmeir F, Leuchs G, Kuamri M, Schwefel HGL. Electro-optic
    frequency comb generation in lithium niobate whispering gallery mode resonators.
    In: <i>2019 Conference on Lasers and Electro-Optics Europe &#38; European Quantum
    Electronics Conference</i>. IEEE; 2019. doi:<a href="https://doi.org/10.1109/cleoe-eqec.2019.8873300">10.1109/cleoe-eqec.2019.8873300</a>'
  apa: 'Rueda Sanchez, A. R., Sedlmeir, F., Leuchs, G., Kuamri, M., &#38; Schwefel,
    H. G. L. (2019). Electro-optic frequency comb generation in lithium niobate whispering
    gallery mode resonators. In <i>2019 Conference on Lasers and Electro-Optics Europe
    &#38; European Quantum Electronics Conference</i>. Munich, Germany: IEEE. <a href="https://doi.org/10.1109/cleoe-eqec.2019.8873300">https://doi.org/10.1109/cleoe-eqec.2019.8873300</a>'
  chicago: Rueda Sanchez, Alfredo R, Florian Sedlmeir, Gerd Leuchs, Madhuri Kuamri,
    and Harald G. L. Schwefel. “Electro-Optic Frequency Comb Generation in Lithium
    Niobate Whispering Gallery Mode Resonators.” In <i>2019 Conference on Lasers and
    Electro-Optics Europe &#38; European Quantum Electronics Conference</i>. IEEE,
    2019. <a href="https://doi.org/10.1109/cleoe-eqec.2019.8873300">https://doi.org/10.1109/cleoe-eqec.2019.8873300</a>.
  ieee: A. R. Rueda Sanchez, F. Sedlmeir, G. Leuchs, M. Kuamri, and H. G. L. Schwefel,
    “Electro-optic frequency comb generation in lithium niobate whispering gallery
    mode resonators,” in <i>2019 Conference on Lasers and Electro-Optics Europe &#38;
    European Quantum Electronics Conference</i>, Munich, Germany, 2019.
  ista: 'Rueda Sanchez AR, Sedlmeir F, Leuchs G, Kuamri M, Schwefel HGL. 2019. Electro-optic
    frequency comb generation in lithium niobate whispering gallery mode resonators.
    2019 Conference on Lasers and Electro-Optics Europe &#38; European Quantum Electronics
    Conference. CLEO: Conference on Lasers and Electro-Optics Europe, 8873300.'
  mla: Rueda Sanchez, Alfredo R., et al. “Electro-Optic Frequency Comb Generation
    in Lithium Niobate Whispering Gallery Mode Resonators.” <i>2019 Conference on
    Lasers and Electro-Optics Europe &#38; European Quantum Electronics Conference</i>,
    8873300, IEEE, 2019, doi:<a href="https://doi.org/10.1109/cleoe-eqec.2019.8873300">10.1109/cleoe-eqec.2019.8873300</a>.
  short: A.R. Rueda Sanchez, F. Sedlmeir, G. Leuchs, M. Kuamri, H.G.L. Schwefel, in:,
    2019 Conference on Lasers and Electro-Optics Europe &#38; European Quantum Electronics
    Conference, IEEE, 2019.
conference:
  end_date: 2019-06-27
  location: Munich, Germany
  name: 'CLEO: Conference on Lasers and Electro-Optics Europe'
  start_date: 2019-06-23
date_created: 2019-11-18T13:58:22Z
date_published: 2019-10-17T00:00:00Z
date_updated: 2023-08-30T07:26:01Z
day: '17'
department:
- _id: JoFi
doi: 10.1109/cleoe-eqec.2019.8873300
external_id:
  isi:
  - '000630002701617'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
publication: 2019 Conference on Lasers and Electro-Optics Europe & European Quantum
  Electronics Conference
publication_identifier:
  isbn:
  - '9781728104690'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electro-optic frequency comb generation in lithium niobate whispering gallery
  mode resonators
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2019'
...
---
_id: '7034'
abstract:
- lang: eng
  text: We find a graph of genus 5 and its drawing on the orientable surface of genus
    4 with every pair of independent edges crossing an even number of times. This
    shows that the strong Hanani–Tutte theorem cannot be extended to the orientable
    surface of genus 4. As a base step in the construction we use a counterexample
    to an extension of the unified Hanani–Tutte theorem on the torus.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Radoslav
  full_name: Fulek, Radoslav
  id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
  last_name: Fulek
  orcid: 0000-0001-8485-1774
- first_name: Jan
  full_name: Kynčl, Jan
  last_name: Kynčl
citation:
  ama: Fulek R, Kynčl J. Counterexample to an extension of the Hanani-Tutte theorem
    on the surface of genus 4. <i>Combinatorica</i>. 2019;39(6):1267-1279. doi:<a
    href="https://doi.org/10.1007/s00493-019-3905-7">10.1007/s00493-019-3905-7</a>
  apa: Fulek, R., &#38; Kynčl, J. (2019). Counterexample to an extension of the Hanani-Tutte
    theorem on the surface of genus 4. <i>Combinatorica</i>. Springer Nature. <a href="https://doi.org/10.1007/s00493-019-3905-7">https://doi.org/10.1007/s00493-019-3905-7</a>
  chicago: Fulek, Radoslav, and Jan Kynčl. “Counterexample to an Extension of the
    Hanani-Tutte Theorem on the Surface of Genus 4.” <i>Combinatorica</i>. Springer
    Nature, 2019. <a href="https://doi.org/10.1007/s00493-019-3905-7">https://doi.org/10.1007/s00493-019-3905-7</a>.
  ieee: R. Fulek and J. Kynčl, “Counterexample to an extension of the Hanani-Tutte
    theorem on the surface of genus 4,” <i>Combinatorica</i>, vol. 39, no. 6. Springer
    Nature, pp. 1267–1279, 2019.
  ista: Fulek R, Kynčl J. 2019. Counterexample to an extension of the Hanani-Tutte
    theorem on the surface of genus 4. Combinatorica. 39(6), 1267–1279.
  mla: Fulek, Radoslav, and Jan Kynčl. “Counterexample to an Extension of the Hanani-Tutte
    Theorem on the Surface of Genus 4.” <i>Combinatorica</i>, vol. 39, no. 6, Springer
    Nature, 2019, pp. 1267–79, doi:<a href="https://doi.org/10.1007/s00493-019-3905-7">10.1007/s00493-019-3905-7</a>.
  short: R. Fulek, J. Kynčl, Combinatorica 39 (2019) 1267–1279.
date_created: 2019-11-18T14:29:50Z
date_published: 2019-10-29T00:00:00Z
date_updated: 2025-04-14T13:52:37Z
day: '29'
department:
- _id: UlWa
doi: 10.1007/s00493-019-3905-7
ec_funded: 1
external_id:
  arxiv:
  - '1709.00508'
  isi:
  - '000493267200003'
intvolume: '        39'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1709.00508
month: '10'
oa: 1
oa_version: Preprint
page: 1267-1279
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 261FA626-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: M02281
  name: Eliminating intersections in drawings of graphs
publication: Combinatorica
publication_identifier:
  eissn:
  - 1439-6912
  issn:
  - 0209-9683
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Counterexample to an extension of the Hanani-Tutte theorem on the surface of
  genus 4
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 39
year: '2019'
...
---
OA_place: repository
OA_type: green
_id: '7035'
abstract:
- lang: eng
  text: 'The aim of this short note is to expound one particular issue that was discussed
    during the talk [10] given at the symposium ”Researches on isometries as preserver
    problems and related topics” at Kyoto RIMS. That is,  the role of Dirac masses
    by  describing  the  isometry group of various metric spaces  of probability  measures.   This  article  is  of  survey  character,  and  it  does  not  contain  any  essentially  new
    results.From an isometric point of view, in some cases, metric spaces of measures
    are similar to C(K)-type function  spaces.   Similarity  means  here  that  their  isometries  are  driven  by  some  nice  transformations
    of  the  underlying  space.   Of  course,  it  depends  on  the  particular  choice  of  the  metric  how  nice  these
    transformations should be.  Sometimes, as we will see, being a homeomorphism is
    enough to generate an isometry.  But sometimes we need more:  the transformation
    must preserve the underlying distance as well.  Statements claiming that isometries
    in questions are necessarily induced by homeomorphisms are called Banach-Stone-type
    results, while results asserting that the underlying transformation is necessarily
    an isometry are termed as isometric rigidity results.As  Dirac  masses  can  be  considered  as  building  bricks  of  the  set  of  all  Borel  measures,  a  natural
    question arises:Is it enough to understand how an isometry acts on the set of
    Dirac masses?  Does this action extend uniquely to all measures?In what follows,
    we will thoroughly investigate this question.'
acknowledgement: "This paper is part of a long term collaboration investigating the
  isometric structure of Wasserstein\r\nspaces. The authors would like to thank the
  warm hospitality and generosity of László Erdós and his\r\ngroup at Institute of
  Science and Technology Austria.\r\nT. Titkos wants to thank Oriental Business and
  Innovation Center ‐ OBIC for providing financial\r\nsupport to participate in the
  symposium at the Kyoto RIMS.\r\nGy. P. Gehér was supported by the Leverhulme Trust
  Early Career Fellowship (ECF‐2018‐125),\r\nand also by the Hungarian National Research,
  Development and Innovation Office (K115383). T.\r\nTitkos was supported by the Hungarian
  National Research, Development and Innovation Office‐ NKFIH\r\n(PD128374), by the
  János Bolyai Research Scholarship of the Hungarian Academy of Sciences, and by the\r\nUNKP‐18‐4‐BGE‐3
  New National Excellence Program of the Ministry of Human Capacities. D. Virosztek\r\nwas
  supported by the ISTFELLOW program of the Institute of Science and Technology Austria
  (project\r\ncode IC1027FELL01 ) and partially supported by the Hungarian National
  Research, Development and\r\nInnovation Office NKFIH (grant no. K124152 and grant
  no. KH129601)"
article_processing_charge: No
author:
- first_name: Gyorgy Pal
  full_name: Geher, Gyorgy Pal
  last_name: Geher
- first_name: Tamas
  full_name: Titkos, Tamas
  last_name: Titkos
- first_name: Daniel
  full_name: Virosztek, Daniel
  id: 48DB45DA-F248-11E8-B48F-1D18A9856A87
  last_name: Virosztek
  orcid: 0000-0003-1109-5511
citation:
  ama: 'Geher GP, Titkos T, Virosztek D. Dirac masses and isometric rigidity. In:
    <i>Kyoto RIMS Kôkyûroku</i>. Vol 2125. Research Institute for Mathematical Sciences,
    Kyoto University; 2019:34-41.'
  apa: 'Geher, G. P., Titkos, T., &#38; Virosztek, D. (2019). Dirac masses and isometric
    rigidity. In <i>Kyoto RIMS Kôkyûroku</i> (Vol. 2125, pp. 34–41). Kyoto, Japan:
    Research Institute for Mathematical Sciences, Kyoto University.'
  chicago: Geher, Gyorgy Pal, Tamas Titkos, and Daniel Virosztek. “Dirac Masses and
    Isometric Rigidity.” In <i>Kyoto RIMS Kôkyûroku</i>, 2125:34–41. Research Institute
    for Mathematical Sciences, Kyoto University, 2019.
  ieee: G. P. Geher, T. Titkos, and D. Virosztek, “Dirac masses and isometric rigidity,”
    in <i>Kyoto RIMS Kôkyûroku</i>, Kyoto, Japan, 2019, vol. 2125, pp. 34–41.
  ista: Geher GP, Titkos T, Virosztek D. 2019. Dirac masses and isometric rigidity.
    Kyoto RIMS Kôkyûroku. Research on isometries as preserver problems and related
    topics vol. 2125, 34–41.
  mla: Geher, Gyorgy Pal, et al. “Dirac Masses and Isometric Rigidity.” <i>Kyoto RIMS
    Kôkyûroku</i>, vol. 2125, Research Institute for Mathematical Sciences, Kyoto
    University, 2019, pp. 34–41.
  short: G.P. Geher, T. Titkos, D. Virosztek, in:, Kyoto RIMS Kôkyûroku, Research
    Institute for Mathematical Sciences, Kyoto University, 2019, pp. 34–41.
conference:
  end_date: 2019-01-30
  location: Kyoto, Japan
  name: Research on isometries as preserver problems and related topics
  start_date: 2019-01-28
corr_author: '1'
date_created: 2019-11-18T15:39:53Z
date_published: 2019-01-30T00:00:00Z
date_updated: 2025-06-30T09:55:30Z
day: '30'
department:
- _id: LaEr
ec_funded: 1
intvolume: '      2125'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.kurims.kyoto-u.ac.jp/~kyodo/kokyuroku/contents/2125.html
month: '01'
oa: 1
oa_version: Submitted Version
page: 34-41
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Kyoto RIMS Kôkyûroku
publication_status: published
publisher: Research Institute for Mathematical Sciences, Kyoto University
quality_controlled: '1'
status: public
title: Dirac masses and isometric rigidity
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2125
year: '2019'
...
---
_id: '7095'
abstract:
- lang: eng
  text: BAX, a member of the BCL2 gene family, controls the committed step of the
    intrinsic apoptotic program. Mitochondrial fragmentation is a commonly observed
    feature of apoptosis, which occurs through the process of mitochondrial fission.
    BAX has consistently been associated with mitochondrial fission, yet how BAX participates
    in the process of mitochondrial fragmentation during apoptosis remains to be tested.
    Time-lapse imaging of BAX recruitment and mitochondrial fragmentation demonstrates
    that rapid mitochondrial fragmentation during apoptosis occurs after the complete
    recruitment of BAX to the mitochondrial outer membrane (MOM). The requirement
    of a fully functioning BAX protein for the fission process was demonstrated further
    in BAX/BAK-deficient HCT116 cells expressing a P168A mutant of BAX. The mutant
    performed fusion to restore the mitochondrial network. but was not demonstrably
    recruited to the MOM after apoptosis induction. Under these conditions, mitochondrial
    fragmentation was blocked. Additionally, we show that loss of the fission protein,
    dynamin-like protein 1 (DRP1), does not temporally affect the initiation time
    or rate of BAX recruitment, but does reduce the final level of BAX recruited to
    the MOM during the late phase of BAX recruitment. These correlative observations
    suggest a model where late-stage BAX oligomers play a functional part of the mitochondrial
    fragmentation machinery in apoptotic cells.
article_number: '16565'
article_processing_charge: No
article_type: original
author:
- first_name: Margaret E
  full_name: Maes, Margaret E
  id: 3838F452-F248-11E8-B48F-1D18A9856A87
  last_name: Maes
  orcid: 0000-0001-9642-1085
- first_name: J. A.
  full_name: Grosser, J. A.
  last_name: Grosser
- first_name: R. L.
  full_name: Fehrman, R. L.
  last_name: Fehrman
- first_name: C. L.
  full_name: Schlamp, C. L.
  last_name: Schlamp
- first_name: R. W.
  full_name: Nickells, R. W.
  last_name: Nickells
citation:
  ama: Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. Completion of BAX
    recruitment correlates with mitochondrial fission during apoptosis. <i>Scientific
    Reports</i>. 2019;9. doi:<a href="https://doi.org/10.1038/s41598-019-53049-w">10.1038/s41598-019-53049-w</a>
  apa: Maes, M. E., Grosser, J. A., Fehrman, R. L., Schlamp, C. L., &#38; Nickells,
    R. W. (2019). Completion of BAX recruitment correlates with mitochondrial fission
    during apoptosis. <i>Scientific Reports</i>. Springer Nature. <a href="https://doi.org/10.1038/s41598-019-53049-w">https://doi.org/10.1038/s41598-019-53049-w</a>
  chicago: Maes, Margaret E, J. A. Grosser, R. L. Fehrman, C. L. Schlamp, and R. W.
    Nickells. “Completion of BAX Recruitment Correlates with Mitochondrial Fission
    during Apoptosis.” <i>Scientific Reports</i>. Springer Nature, 2019. <a href="https://doi.org/10.1038/s41598-019-53049-w">https://doi.org/10.1038/s41598-019-53049-w</a>.
  ieee: M. E. Maes, J. A. Grosser, R. L. Fehrman, C. L. Schlamp, and R. W. Nickells,
    “Completion of BAX recruitment correlates with mitochondrial fission during apoptosis,”
    <i>Scientific Reports</i>, vol. 9. Springer Nature, 2019.
  ista: Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. 2019. Completion
    of BAX recruitment correlates with mitochondrial fission during apoptosis. Scientific
    Reports. 9, 16565.
  mla: Maes, Margaret E., et al. “Completion of BAX Recruitment Correlates with Mitochondrial
    Fission during Apoptosis.” <i>Scientific Reports</i>, vol. 9, 16565, Springer
    Nature, 2019, doi:<a href="https://doi.org/10.1038/s41598-019-53049-w">10.1038/s41598-019-53049-w</a>.
  short: M.E. Maes, J.A. Grosser, R.L. Fehrman, C.L. Schlamp, R.W. Nickells, Scientific
    Reports 9 (2019).
date_created: 2019-11-25T07:45:17Z
date_published: 2019-11-12T00:00:00Z
date_updated: 2023-08-30T07:26:54Z
day: '12'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1038/s41598-019-53049-w
external_id:
  isi:
  - '000495857600019'
  pmid:
  - '31719602'
file:
- access_level: open_access
  checksum: 9ab397ed9c1c454b34bffb8cc863d734
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-25T07:49:52Z
  date_updated: 2020-07-14T12:47:49Z
  file_id: '7096'
  file_name: 2019_ScientificReports_Maes.pdf
  file_size: 6467393
  relation: main_file
file_date_updated: 2020-07-14T12:47:49Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Scientific Reports
publication_identifier:
  eissn:
  - 2045-2322
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Completion of BAX recruitment correlates with mitochondrial fission during
  apoptosis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2019'
...
---
_id: '7097'
abstract:
- lang: eng
  text: Early endosomes, also called sorting endosomes, are known to mature into late
    endosomesvia the Rab5-mediated endolysosomal trafficking pathway. Thus, early
    endosome existence isthought to be maintained by the continual fusion of transport
    vesicles from the plasmamembrane and thetrans-Golgi network (TGN). Here we show
    instead that endocytosis isdispensable and post-Golgi vesicle transport is crucial
    for the formation of endosomes andthe subsequent endolysosomal traffic regulated
    by yeast Rab5 Vps21p. Fittingly, all threeproteins required for endosomal nucleotide
    exchange on Vps21p arefirst recruited to theTGN  before  transport  to  the  endosome,  namely  the  GEF  Vps9p
    and  the  epsin-relatedadaptors Ent3/5p. The TGN recruitment of these components
    is distinctly controlled, withVps9p appearing to require the Arf1p GTPase, and
    the Rab11s, Ypt31p/32p. These resultsprovide a different view of endosome formation
    and identify the TGN as a critical location forregulating progress through the
    endolysosomal trafficking pathway.
article_number: '419'
article_processing_charge: No
article_type: original
author:
- first_name: Makoto
  full_name: Nagano, Makoto
  last_name: Nagano
- first_name: Junko Y.
  full_name: Toshima, Junko Y.
  last_name: Toshima
- first_name: Daria E
  full_name: Siekhaus, Daria E
  id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
  last_name: Siekhaus
  orcid: 0000-0001-8323-8353
- first_name: Jiro
  full_name: Toshima, Jiro
  last_name: Toshima
citation:
  ama: Nagano M, Toshima JY, Siekhaus DE, Toshima J. Rab5-mediated endosome formation
    is regulated at the trans-Golgi network. <i>Communications Biology</i>. 2019;2(1).
    doi:<a href="https://doi.org/10.1038/s42003-019-0670-5">10.1038/s42003-019-0670-5</a>
  apa: Nagano, M., Toshima, J. Y., Siekhaus, D. E., &#38; Toshima, J. (2019). Rab5-mediated
    endosome formation is regulated at the trans-Golgi network. <i>Communications
    Biology</i>. Springer Nature. <a href="https://doi.org/10.1038/s42003-019-0670-5">https://doi.org/10.1038/s42003-019-0670-5</a>
  chicago: Nagano, Makoto, Junko Y. Toshima, Daria E Siekhaus, and Jiro Toshima. “Rab5-Mediated
    Endosome Formation Is Regulated at the Trans-Golgi Network.” <i>Communications
    Biology</i>. Springer Nature, 2019. <a href="https://doi.org/10.1038/s42003-019-0670-5">https://doi.org/10.1038/s42003-019-0670-5</a>.
  ieee: M. Nagano, J. Y. Toshima, D. E. Siekhaus, and J. Toshima, “Rab5-mediated endosome
    formation is regulated at the trans-Golgi network,” <i>Communications Biology</i>,
    vol. 2, no. 1. Springer Nature, 2019.
  ista: Nagano M, Toshima JY, Siekhaus DE, Toshima J. 2019. Rab5-mediated endosome
    formation is regulated at the trans-Golgi network. Communications Biology. 2(1),
    419.
  mla: Nagano, Makoto, et al. “Rab5-Mediated Endosome Formation Is Regulated at the
    Trans-Golgi Network.” <i>Communications Biology</i>, vol. 2, no. 1, 419, Springer
    Nature, 2019, doi:<a href="https://doi.org/10.1038/s42003-019-0670-5">10.1038/s42003-019-0670-5</a>.
  short: M. Nagano, J.Y. Toshima, D.E. Siekhaus, J. Toshima, Communications Biology
    2 (2019).
date_created: 2019-11-25T07:55:01Z
date_published: 2019-11-15T00:00:00Z
date_updated: 2023-08-30T07:27:55Z
day: '15'
ddc:
- '570'
department:
- _id: DaSi
doi: 10.1038/s42003-019-0670-5
external_id:
  isi:
  - '000496767800005'
file:
- access_level: open_access
  checksum: c63c69a264fc8a0e52f2b0d482f3bdae
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-25T07:58:05Z
  date_updated: 2020-07-14T12:47:49Z
  file_id: '7098'
  file_name: 2019_CommunicBiology_Nagano.pdf
  file_size: 2626069
  relation: main_file
file_date_updated: 2020-07-14T12:47:49Z
has_accepted_license: '1'
intvolume: '         2'
isi: 1
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Communications Biology
publication_identifier:
  issn:
  - 2399-3642
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rab5-mediated endosome formation is regulated at the trans-Golgi network
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2
year: '2019'
...
---
_id: '7099'
acknowledgement: "The authors thank Gabi Schmid for excellent technical support. We
  also thank\r\nDr. H. Harada, Dr. W. Kaufmann, and Dr. B. Kapelari for testing the
  specificity\r\nof some of the antibodies used in this study on replicas. Funding
  was provided\r\nby the Austrian Science Fund (Fonds zur Fo¨ rderung der Wissenschaftlichen\r\nForschung)
  Sonderforschungsbereich grants F44-17 (to F.jF.), F44-10 and\r\nP25375-B24 (to N.S.),
  and P26680 (to G.S.) and by the Novartis Research\r\nFoundation and the Swiss National
  Science Foundation (to A.L). We also thank\r\nProf. M. Capogna for reading a previous
  version of the manuscript."
article_processing_charge: No
article_type: original
author:
- first_name: Yu
  full_name: Kasugai, Yu
  last_name: Kasugai
- first_name: Elisabeth
  full_name: Vogel, Elisabeth
  last_name: Vogel
- first_name: Heide
  full_name: Hörtnagl, Heide
  last_name: Hörtnagl
- first_name: Sabine
  full_name: Schönherr, Sabine
  last_name: Schönherr
- first_name: Enrica
  full_name: Paradiso, Enrica
  last_name: Paradiso
- first_name: Markus
  full_name: Hauschild, Markus
  last_name: Hauschild
- first_name: Georg
  full_name: Göbel, Georg
  last_name: Göbel
- first_name: Ivan
  full_name: Milenkovic, Ivan
  last_name: Milenkovic
- first_name: Yvan
  full_name: Peterschmitt, Yvan
  last_name: Peterschmitt
- first_name: Ramon
  full_name: Tasan, Ramon
  last_name: Tasan
- first_name: Günther
  full_name: Sperk, Günther
  last_name: Sperk
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Werner
  full_name: Sieghart, Werner
  last_name: Sieghart
- first_name: Nicolas
  full_name: Singewald, Nicolas
  last_name: Singewald
- first_name: Andreas
  full_name: Lüthi, Andreas
  last_name: Lüthi
- first_name: Francesco
  full_name: Ferraguti, Francesco
  last_name: Ferraguti
citation:
  ama: Kasugai Y, Vogel E, Hörtnagl H, et al. Structural and functional remodeling
    of amygdala GABAergic synapses in associative fear learning. <i>Neuron</i>. 2019;104(4):781-794.e4.
    doi:<a href="https://doi.org/10.1016/j.neuron.2019.08.013">10.1016/j.neuron.2019.08.013</a>
  apa: Kasugai, Y., Vogel, E., Hörtnagl, H., Schönherr, S., Paradiso, E., Hauschild,
    M., … Ferraguti, F. (2019). Structural and functional remodeling of amygdala GABAergic
    synapses in associative fear learning. <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2019.08.013">https://doi.org/10.1016/j.neuron.2019.08.013</a>
  chicago: Kasugai, Yu, Elisabeth Vogel, Heide Hörtnagl, Sabine Schönherr, Enrica
    Paradiso, Markus Hauschild, Georg Göbel, et al. “Structural and Functional Remodeling
    of Amygdala GABAergic Synapses in Associative Fear Learning.” <i>Neuron</i>. Elsevier,
    2019. <a href="https://doi.org/10.1016/j.neuron.2019.08.013">https://doi.org/10.1016/j.neuron.2019.08.013</a>.
  ieee: Y. Kasugai <i>et al.</i>, “Structural and functional remodeling of amygdala
    GABAergic synapses in associative fear learning,” <i>Neuron</i>, vol. 104, no.
    4. Elsevier, p. 781–794.e4, 2019.
  ista: Kasugai Y, Vogel E, Hörtnagl H, Schönherr S, Paradiso E, Hauschild M, Göbel
    G, Milenkovic I, Peterschmitt Y, Tasan R, Sperk G, Shigemoto R, Sieghart W, Singewald
    N, Lüthi A, Ferraguti F. 2019. Structural and functional remodeling of amygdala
    GABAergic synapses in associative fear learning. Neuron. 104(4), 781–794.e4.
  mla: Kasugai, Yu, et al. “Structural and Functional Remodeling of Amygdala GABAergic
    Synapses in Associative Fear Learning.” <i>Neuron</i>, vol. 104, no. 4, Elsevier,
    2019, p. 781–794.e4, doi:<a href="https://doi.org/10.1016/j.neuron.2019.08.013">10.1016/j.neuron.2019.08.013</a>.
  short: Y. Kasugai, E. Vogel, H. Hörtnagl, S. Schönherr, E. Paradiso, M. Hauschild,
    G. Göbel, I. Milenkovic, Y. Peterschmitt, R. Tasan, G. Sperk, R. Shigemoto, W.
    Sieghart, N. Singewald, A. Lüthi, F. Ferraguti, Neuron 104 (2019) 781–794.e4.
date_created: 2019-11-25T08:02:39Z
date_published: 2019-11-20T00:00:00Z
date_updated: 2023-08-30T07:28:22Z
day: '20'
ddc:
- '571'
- '599'
department:
- _id: RySh
doi: 10.1016/j.neuron.2019.08.013
external_id:
  isi:
  - '000497963500017'
  pmid:
  - '31543297'
has_accepted_license: '1'
intvolume: '       104'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.neuron.2019.08.013
month: '11'
oa: 1
oa_version: Published Version
page: 781-794.e4
pmid: 1
publication: Neuron
publication_identifier:
  issn:
  - 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural and functional remodeling of amygdala GABAergic synapses in associative
  fear learning
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 104
year: '2019'
...
---
_id: '7100'
abstract:
- lang: eng
  text: We present microscopic derivations of the defocusing two-dimensional cubic
    nonlinear Schrödinger equation and the Gross–Pitaevskii equation starting froman
    interacting N-particle system of bosons. We consider the interaction potential
    to be given either by Wβ(x)=N−1+2βW(Nβx), for any β>0, or to be given by VN(x)=e2NV(eNx),
    for some spherical symmetric, nonnegative and compactly supported W,V∈L∞(R2,R).
    In both cases we prove the convergence of the reduced density corresponding to
    the exact time evolution to the projector onto the solution of the corresponding
    nonlinear Schrödinger equation in trace norm. For the latter potential VN we show
    that it is crucial to take the microscopic structure of the condensate into account
    in order to obtain the correct dynamics.
acknowledgement: OA fund by IST Austria
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Maximilian
  full_name: Jeblick, Maximilian
  last_name: Jeblick
- first_name: Nikolai K
  full_name: Leopold, Nikolai K
  id: 4BC40BEC-F248-11E8-B48F-1D18A9856A87
  last_name: Leopold
  orcid: 0000-0002-0495-6822
- first_name: Peter
  full_name: Pickl, Peter
  last_name: Pickl
citation:
  ama: Jeblick M, Leopold NK, Pickl P. Derivation of the time dependent Gross–Pitaevskii
    equation in two dimensions. <i>Communications in Mathematical Physics</i>. 2019;372(1):1-69.
    doi:<a href="https://doi.org/10.1007/s00220-019-03599-x">10.1007/s00220-019-03599-x</a>
  apa: Jeblick, M., Leopold, N. K., &#38; Pickl, P. (2019). Derivation of the time
    dependent Gross–Pitaevskii equation in two dimensions. <i>Communications in Mathematical
    Physics</i>. Springer Nature. <a href="https://doi.org/10.1007/s00220-019-03599-x">https://doi.org/10.1007/s00220-019-03599-x</a>
  chicago: Jeblick, Maximilian, Nikolai K Leopold, and Peter Pickl. “Derivation of
    the Time Dependent Gross–Pitaevskii Equation in Two Dimensions.” <i>Communications
    in Mathematical Physics</i>. Springer Nature, 2019. <a href="https://doi.org/10.1007/s00220-019-03599-x">https://doi.org/10.1007/s00220-019-03599-x</a>.
  ieee: M. Jeblick, N. K. Leopold, and P. Pickl, “Derivation of the time dependent
    Gross–Pitaevskii equation in two dimensions,” <i>Communications in Mathematical
    Physics</i>, vol. 372, no. 1. Springer Nature, pp. 1–69, 2019.
  ista: Jeblick M, Leopold NK, Pickl P. 2019. Derivation of the time dependent Gross–Pitaevskii
    equation in two dimensions. Communications in Mathematical Physics. 372(1), 1–69.
  mla: Jeblick, Maximilian, et al. “Derivation of the Time Dependent Gross–Pitaevskii
    Equation in Two Dimensions.” <i>Communications in Mathematical Physics</i>, vol.
    372, no. 1, Springer Nature, 2019, pp. 1–69, doi:<a href="https://doi.org/10.1007/s00220-019-03599-x">10.1007/s00220-019-03599-x</a>.
  short: M. Jeblick, N.K. Leopold, P. Pickl, Communications in Mathematical Physics
    372 (2019) 1–69.
corr_author: '1'
date_created: 2019-11-25T08:08:02Z
date_published: 2019-11-08T00:00:00Z
date_updated: 2025-04-14T07:27:01Z
day: '08'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1007/s00220-019-03599-x
ec_funded: 1
external_id:
  isi:
  - '000495193700002'
file:
- access_level: open_access
  checksum: cd283b475dd739e04655315abd46f528
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-25T08:11:11Z
  date_updated: 2020-07-14T12:47:49Z
  file_id: '7101'
  file_name: 2019_CommMathPhys_Jeblick.pdf
  file_size: 884469
  relation: main_file
file_date_updated: 2020-07-14T12:47:49Z
has_accepted_license: '1'
intvolume: '       372'
isi: 1
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 1-69
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Communications in Mathematical Physics
publication_identifier:
  eissn:
  - 1432-0916
  issn:
  - 0010-3616
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Derivation of the time dependent Gross–Pitaevskii equation in two dimensions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 372
year: '2019'
...
---
_id: '7103'
abstract:
- lang: eng
  text: Origin and functions of intermittent transitions among sleep stages, including
    short awakenings and arousals, constitute a challenge to the current homeostatic
    framework for sleep regulation, focusing on factors modulating sleep over large
    time scales. Here we propose that the complex micro-architecture characterizing
    the sleep-wake cycle results from an underlying non-equilibrium critical dynamics,
    bridging collective behaviors across spatio-temporal scales. We investigate θ
    and δ wave dynamics in control rats and in rats with lesions of sleep-promoting
    neurons in the parafacial zone. We demonstrate that intermittent bursts in θ and
    δ rhythms exhibit a complex temporal organization, with long-range power-law correlations
    and a robust duality of power law (θ-bursts, active phase) and exponential-like
    (δ-bursts, quiescent phase) duration distributions, typical features of non-equilibrium
    systems self-organizing at criticality. Crucially, such temporal organization
    relates to anti-correlated coupling between θ- and δ-bursts, and is independent
    of the dominant physiologic state and lesions, a solid indication of a basic principle
    in sleep dynamics.
article_number: e1007268
article_processing_charge: No
article_type: original
author:
- first_name: Jilin W. J. L.
  full_name: Wang, Jilin W. J. L.
  last_name: Wang
- first_name: Fabrizio
  full_name: Lombardi, Fabrizio
  id: A057D288-3E88-11E9-986D-0CF4E5697425
  last_name: Lombardi
  orcid: 0000-0003-2623-5249
- first_name: Xiyun
  full_name: Zhang, Xiyun
  last_name: Zhang
- first_name: Christelle
  full_name: Anaclet, Christelle
  last_name: Anaclet
- first_name: Plamen Ch.
  full_name: Ivanov, Plamen Ch.
  last_name: Ivanov
citation:
  ama: Wang JWJL, Lombardi F, Zhang X, Anaclet C, Ivanov PC. Non-equilibrium critical
    dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and
    wake micro-architecture. <i>PLoS Computational Biology</i>. 2019;15(11). doi:<a
    href="https://doi.org/10.1371/journal.pcbi.1007268">10.1371/journal.pcbi.1007268</a>
  apa: Wang, J. W. J. L., Lombardi, F., Zhang, X., Anaclet, C., &#38; Ivanov, P. C.
    (2019). Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental
    characteristic of sleep and wake micro-architecture. <i>PLoS Computational Biology</i>.
    Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1007268">https://doi.org/10.1371/journal.pcbi.1007268</a>
  chicago: Wang, Jilin W. J. L., Fabrizio Lombardi, Xiyun Zhang, Christelle Anaclet,
    and Plamen Ch. Ivanov. “Non-Equilibrium Critical Dynamics of Bursts in θ and δ
    Rhythms as Fundamental Characteristic of Sleep and Wake Micro-Architecture.” <i>PLoS
    Computational Biology</i>. Public Library of Science, 2019. <a href="https://doi.org/10.1371/journal.pcbi.1007268">https://doi.org/10.1371/journal.pcbi.1007268</a>.
  ieee: J. W. J. L. Wang, F. Lombardi, X. Zhang, C. Anaclet, and P. C. Ivanov, “Non-equilibrium
    critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of
    sleep and wake micro-architecture,” <i>PLoS Computational Biology</i>, vol. 15,
    no. 11. Public Library of Science, 2019.
  ista: Wang JWJL, Lombardi F, Zhang X, Anaclet C, Ivanov PC. 2019. Non-equilibrium
    critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of
    sleep and wake micro-architecture. PLoS Computational Biology. 15(11), e1007268.
  mla: Wang, Jilin W. J. L., et al. “Non-Equilibrium Critical Dynamics of Bursts in
    θ and δ Rhythms as Fundamental Characteristic of Sleep and Wake Micro-Architecture.”
    <i>PLoS Computational Biology</i>, vol. 15, no. 11, e1007268, Public Library of
    Science, 2019, doi:<a href="https://doi.org/10.1371/journal.pcbi.1007268">10.1371/journal.pcbi.1007268</a>.
  short: J.W.J.L. Wang, F. Lombardi, X. Zhang, C. Anaclet, P.C. Ivanov, PLoS Computational
    Biology 15 (2019).
date_created: 2019-11-25T08:20:47Z
date_published: 2019-11-01T00:00:00Z
date_updated: 2025-04-14T07:44:06Z
day: '01'
ddc:
- '570'
- '000'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1007268
ec_funded: 1
external_id:
  isi:
  - '000500976100014'
  pmid:
  - '31725712'
file:
- access_level: open_access
  checksum: 2a096a9c6dcc6eaa94077b2603bc6c12
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-25T08:24:01Z
  date_updated: 2020-07-14T12:47:49Z
  file_id: '7104'
  file_name: 2019_PLOSComBio_Wang.pdf
  file_size: 3982516
  relation: main_file
file_date_updated: 2020-07-14T12:47:49Z
has_accepted_license: '1'
intvolume: '        15'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: PLoS Computational Biology
publication_identifier:
  issn:
  - 1553-7358
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental
  characteristic of sleep and wake micro-architecture
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2019'
...
---
_id: '7105'
abstract:
- lang: eng
  text: Cell migration is hypothesized to involve a cycle of behaviours beginning
    with leading edge extension. However, recent evidence suggests that the leading
    edge may be dispensable for migration, raising the question of what actually controls
    cell directionality. Here, we exploit the embryonic migration of Drosophila macrophages
    to bridge the different temporal scales of the behaviours controlling motility.
    This approach reveals that edge fluctuations during random motility are not persistent
    and are weakly correlated with motion. In contrast, flow of the actin network
    behind the leading edge is highly persistent. Quantification of actin flow structure
    during migration reveals a stable organization and asymmetry in the cell-wide
    flowfield that strongly correlates with cell directionality. This organization
    is regulated by a gradient of actin network compression and destruction, which
    is controlled by myosin contraction and cofilin-mediated disassembly. It is this
    stable actin-flow polarity, which integrates rapid fluctuations of the leading
    edge, that controls inherent cellular persistence.
article_processing_charge: No
article_type: original
author:
- first_name: Lawrence
  full_name: Yolland, Lawrence
  last_name: Yolland
- first_name: Mubarik
  full_name: Burki, Mubarik
  last_name: Burki
- first_name: Stefania
  full_name: Marcotti, Stefania
  last_name: Marcotti
- first_name: Andrei
  full_name: Luchici, Andrei
  last_name: Luchici
- first_name: Fiona N.
  full_name: Kenny, Fiona N.
  last_name: Kenny
- first_name: John Robert
  full_name: Davis, John Robert
  last_name: Davis
- first_name: Eduardo
  full_name: Serna-Morales, Eduardo
  last_name: Serna-Morales
- first_name: Jan
  full_name: Müller, Jan
  id: AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
  last_name: Müller
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Andrew
  full_name: Davidson, Andrew
  last_name: Davidson
- first_name: Will
  full_name: Wood, Will
  last_name: Wood
- first_name: Linus J.
  full_name: Schumacher, Linus J.
  last_name: Schumacher
- first_name: Robert G.
  full_name: Endres, Robert G.
  last_name: Endres
- first_name: Mark
  full_name: Miodownik, Mark
  last_name: Miodownik
- first_name: Brian M.
  full_name: Stramer, Brian M.
  last_name: Stramer
citation:
  ama: Yolland L, Burki M, Marcotti S, et al. Persistent and polarized global actin
    flow is essential for directionality during cell migration. <i>Nature Cell Biology</i>.
    2019;21(11):1370-1381. doi:<a href="https://doi.org/10.1038/s41556-019-0411-5">10.1038/s41556-019-0411-5</a>
  apa: Yolland, L., Burki, M., Marcotti, S., Luchici, A., Kenny, F. N., Davis, J.
    R., … Stramer, B. M. (2019). Persistent and polarized global actin flow is essential
    for directionality during cell migration. <i>Nature Cell Biology</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41556-019-0411-5">https://doi.org/10.1038/s41556-019-0411-5</a>
  chicago: Yolland, Lawrence, Mubarik Burki, Stefania Marcotti, Andrei Luchici, Fiona
    N. Kenny, John Robert Davis, Eduardo Serna-Morales, et al. “Persistent and Polarized
    Global Actin Flow Is Essential for Directionality during Cell Migration.” <i>Nature
    Cell Biology</i>. Springer Nature, 2019. <a href="https://doi.org/10.1038/s41556-019-0411-5">https://doi.org/10.1038/s41556-019-0411-5</a>.
  ieee: L. Yolland <i>et al.</i>, “Persistent and polarized global actin flow is essential
    for directionality during cell migration,” <i>Nature Cell Biology</i>, vol. 21,
    no. 11. Springer Nature, pp. 1370–1381, 2019.
  ista: Yolland L, Burki M, Marcotti S, Luchici A, Kenny FN, Davis JR, Serna-Morales
    E, Müller J, Sixt MK, Davidson A, Wood W, Schumacher LJ, Endres RG, Miodownik
    M, Stramer BM. 2019. Persistent and polarized global actin flow is essential for
    directionality during cell migration. Nature Cell Biology. 21(11), 1370–1381.
  mla: Yolland, Lawrence, et al. “Persistent and Polarized Global Actin Flow Is Essential
    for Directionality during Cell Migration.” <i>Nature Cell Biology</i>, vol. 21,
    no. 11, Springer Nature, 2019, pp. 1370–81, doi:<a href="https://doi.org/10.1038/s41556-019-0411-5">10.1038/s41556-019-0411-5</a>.
  short: L. Yolland, M. Burki, S. Marcotti, A. Luchici, F.N. Kenny, J.R. Davis, E.
    Serna-Morales, J. Müller, M.K. Sixt, A. Davidson, W. Wood, L.J. Schumacher, R.G.
    Endres, M. Miodownik, B.M. Stramer, Nature Cell Biology 21 (2019) 1370–1381.
date_created: 2019-11-25T08:55:00Z
date_published: 2019-11-01T00:00:00Z
date_updated: 2023-09-06T11:08:52Z
day: '01'
department:
- _id: MiSi
doi: 10.1038/s41556-019-0411-5
external_id:
  isi:
  - '000495888300009'
  pmid:
  - '31685997'
intvolume: '        21'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025891
month: '11'
oa: 1
oa_version: Submitted Version
page: 1370-1381
pmid: 1
publication: Nature Cell Biology
publication_identifier:
  eissn:
  - 1476-4679
  issn:
  - 1465-7392
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Persistent and polarized global actin flow is essential for directionality
  during cell migration
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 21
year: '2019'
...
---
_id: '7106'
abstract:
- lang: eng
  text: PIN-FORMED (PIN) transporters mediate directional, intercellular movement
    of the phytohormone auxin in land plants. To elucidate the evolutionary origins
    of this developmentally crucial mechanism, we analysed the single PIN homologue
    of a simple green alga Klebsormidium flaccidum. KfPIN functions as a plasma membrane-localized
    auxin exporter in land plants and heterologous models. While its role in algae
    remains unclear, PIN-driven auxin export is probably an ancient and conserved
    trait within streptophytes.
article_processing_charge: No
article_type: original
author:
- first_name: Roman
  full_name: Skokan, Roman
  last_name: Skokan
- first_name: Eva
  full_name: Medvecká, Eva
  last_name: Medvecká
- first_name: Tom
  full_name: Viaene, Tom
  last_name: Viaene
- first_name: Stanislav
  full_name: Vosolsobě, Stanislav
  last_name: Vosolsobě
- first_name: Marta
  full_name: Zwiewka, Marta
  last_name: Zwiewka
- first_name: Karel
  full_name: Müller, Karel
  last_name: Müller
- first_name: Petr
  full_name: Skůpa, Petr
  last_name: Skůpa
- first_name: Michal
  full_name: Karady, Michal
  last_name: Karady
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  last_name: Zhang
- first_name: Dorina P.
  full_name: Janacek, Dorina P.
  last_name: Janacek
- first_name: Ulrich Z.
  full_name: Hammes, Ulrich Z.
  last_name: Hammes
- first_name: Karin
  full_name: Ljung, Karin
  last_name: Ljung
- first_name: Tomasz
  full_name: Nodzyński, Tomasz
  last_name: Nodzyński
- first_name: Jan
  full_name: Petrášek, Jan
  last_name: Petrášek
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Skokan R, Medvecká E, Viaene T, et al. PIN-driven auxin transport emerged early
    in streptophyte evolution. <i>Nature Plants</i>. 2019;5(11):1114-1119. doi:<a
    href="https://doi.org/10.1038/s41477-019-0542-5">10.1038/s41477-019-0542-5</a>
  apa: Skokan, R., Medvecká, E., Viaene, T., Vosolsobě, S., Zwiewka, M., Müller, K.,
    … Friml, J. (2019). PIN-driven auxin transport emerged early in streptophyte evolution.
    <i>Nature Plants</i>. Springer Nature. <a href="https://doi.org/10.1038/s41477-019-0542-5">https://doi.org/10.1038/s41477-019-0542-5</a>
  chicago: Skokan, Roman, Eva Medvecká, Tom Viaene, Stanislav Vosolsobě, Marta Zwiewka,
    Karel Müller, Petr Skůpa, et al. “PIN-Driven Auxin Transport Emerged Early in
    Streptophyte Evolution.” <i>Nature Plants</i>. Springer Nature, 2019. <a href="https://doi.org/10.1038/s41477-019-0542-5">https://doi.org/10.1038/s41477-019-0542-5</a>.
  ieee: R. Skokan <i>et al.</i>, “PIN-driven auxin transport emerged early in streptophyte
    evolution,” <i>Nature Plants</i>, vol. 5, no. 11. Springer Nature, pp. 1114–1119,
    2019.
  ista: Skokan R, Medvecká E, Viaene T, Vosolsobě S, Zwiewka M, Müller K, Skůpa P,
    Karady M, Zhang Y, Janacek DP, Hammes UZ, Ljung K, Nodzyński T, Petrášek J, Friml
    J. 2019. PIN-driven auxin transport emerged early in streptophyte evolution. Nature
    Plants. 5(11), 1114–1119.
  mla: Skokan, Roman, et al. “PIN-Driven Auxin Transport Emerged Early in Streptophyte
    Evolution.” <i>Nature Plants</i>, vol. 5, no. 11, Springer Nature, 2019, pp. 1114–19,
    doi:<a href="https://doi.org/10.1038/s41477-019-0542-5">10.1038/s41477-019-0542-5</a>.
  short: R. Skokan, E. Medvecká, T. Viaene, S. Vosolsobě, M. Zwiewka, K. Müller, P.
    Skůpa, M. Karady, Y. Zhang, D.P. Janacek, U.Z. Hammes, K. Ljung, T. Nodzyński,
    J. Petrášek, J. Friml, Nature Plants 5 (2019) 1114–1119.
date_created: 2019-11-25T09:08:04Z
date_published: 2019-11-01T00:00:00Z
date_updated: 2025-04-14T07:45:04Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41477-019-0542-5
ec_funded: 1
external_id:
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language:
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oa_version: Submitted Version
page: 1114-1119
pmid: 1
project:
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  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Nature Plants
publication_identifier:
  issn:
  - 2055-0278
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: PIN-driven auxin transport emerged early in streptophyte evolution
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 5
year: '2019'
...
---
_id: '7108'
abstract:
- lang: eng
  text: We prove that for every d ≥ 2, deciding if a pure, d-dimensional, simplicial
    complex is shellable is NP-hard, hence NP-complete. This resolves a question raised,
    e.g., by Danaraj and Klee in 1978. Our reduction also yields that for every d
    ≥ 2 and k ≥ 0, deciding if a pure, d-dimensional, simplicial complex is k-decomposable
    is NP-hard. For d ≥ 3, both problems remain NP-hard when restricted to contractible
    pure d-dimensional complexes. Another simple corollary of our result is that it
    is NP-hard to decide whether a given poset is CL-shellable.
article_number: '21'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Pavel
  full_name: Patak, Pavel
  id: B593B804-1035-11EA-B4F1-947645A5BB83
  last_name: Patak
- first_name: Zuzana
  full_name: Patakova, Zuzana
  id: 48B57058-F248-11E8-B48F-1D18A9856A87
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  last_name: Tancer
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: Goaoc X, Patak P, Patakova Z, Tancer M, Wagner U. Shellability is NP-complete.
    <i>Journal of the ACM</i>. 2019;66(3). doi:<a href="https://doi.org/10.1145/3314024">10.1145/3314024</a>
  apa: Goaoc, X., Patak, P., Patakova, Z., Tancer, M., &#38; Wagner, U. (2019). Shellability
    is NP-complete. <i>Journal of the ACM</i>. ACM. <a href="https://doi.org/10.1145/3314024">https://doi.org/10.1145/3314024</a>
  chicago: Goaoc, Xavier, Pavel Patak, Zuzana Patakova, Martin Tancer, and Uli Wagner.
    “Shellability Is NP-Complete.” <i>Journal of the ACM</i>. ACM, 2019. <a href="https://doi.org/10.1145/3314024">https://doi.org/10.1145/3314024</a>.
  ieee: X. Goaoc, P. Patak, Z. Patakova, M. Tancer, and U. Wagner, “Shellability is
    NP-complete,” <i>Journal of the ACM</i>, vol. 66, no. 3. ACM, 2019.
  ista: Goaoc X, Patak P, Patakova Z, Tancer M, Wagner U. 2019. Shellability is NP-complete.
    Journal of the ACM. 66(3), 21.
  mla: Goaoc, Xavier, et al. “Shellability Is NP-Complete.” <i>Journal of the ACM</i>,
    vol. 66, no. 3, 21, ACM, 2019, doi:<a href="https://doi.org/10.1145/3314024">10.1145/3314024</a>.
  short: X. Goaoc, P. Patak, Z. Patakova, M. Tancer, U. Wagner, Journal of the ACM
    66 (2019).
date_created: 2019-11-26T10:13:59Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2025-06-04T07:49:03Z
day: '01'
department:
- _id: UlWa
doi: 10.1145/3314024
external_id:
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  url: https://arxiv.org/abs/1711.08436
month: '06'
oa: 1
oa_version: Preprint
publication: Journal of the ACM
publication_identifier:
  issn:
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publication_status: published
publisher: ACM
quality_controlled: '1'
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title: Shellability is NP-complete
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 66
year: '2019'
...
