---
OA_place: publisher
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acknowledged_ssus:
- _id: Bio
- _id: LifeSc
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: David
full_name: Babic, David
id: db566d23-f6e0-11ea-865d-e6f270e968e7
last_name: Babic
citation:
ama: Babic D. Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana.
2025. doi:10.15479/AT-ISTA-20362
apa: Babic, D. (2025). Mechanisms of auxin-mediated early embryogenesis in Arabidopsis
thaliana. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20362
chicago: Babic, David. “Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis
Thaliana.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20362.
ieee: D. Babic, “Mechanisms of auxin-mediated early embryogenesis in Arabidopsis
thaliana,” Institute of Science and Technology Austria, 2025.
ista: Babic D. 2025. Mechanisms of auxin-mediated early embryogenesis in Arabidopsis
thaliana. Institute of Science and Technology Austria.
mla: Babic, David. Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis
Thaliana. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20362.
short: D. Babic, Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis
Thaliana, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-09-17T13:28:01Z
date_published: 2025-09-18T00:00:00Z
date_updated: 2026-04-07T11:52:02Z
day: '18'
ddc:
- '580'
degree_awarded: PhD
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doi: 10.15479/AT-ISTA-20362
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issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
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relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
title: Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20393'
acknowledged_ssus:
- _id: Bio
- _id: PreCl
- _id: LifeSc
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Kasumi
full_name: Kishi, Kasumi
id: 3065DFC4-F248-11E8-B48F-1D18A9856A87
last_name: Kishi
orcid: 0000-0001-6060-4795
citation:
ama: Kishi K. Regulation of notochord and floor plate size during mouse development.
2025. doi:10.15479/AT-ISTA-20393
apa: Kishi, K. (2025). Regulation of notochord and floor plate size during mouse
development. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20393
chicago: Kishi, Kasumi. “Regulation of Notochord and Floor Plate Size during Mouse
Development.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20393.
ieee: K. Kishi, “Regulation of notochord and floor plate size during mouse development,”
Institute of Science and Technology Austria, 2025.
ista: Kishi K. 2025. Regulation of notochord and floor plate size during mouse development.
Institute of Science and Technology Austria.
mla: Kishi, Kasumi. Regulation of Notochord and Floor Plate Size during Mouse
Development. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20393.
short: K. Kishi, Regulation of Notochord and Floor Plate Size during Mouse Development,
Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-09-25T10:08:10Z
date_published: 2025-09-24T00:00:00Z
date_updated: 2026-04-14T09:50:52Z
day: '24'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: AnKi
- _id: EdHa
doi: 10.15479/AT-ISTA-20393
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language:
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month: '09'
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publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '18481'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Anna
full_name: Kicheva, Anna
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
title: Regulation of notochord and floor plate size during mouse development
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20415'
acknowledged_ssus:
- _id: LifeSc
- _id: EM-Fac
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Seungho
full_name: Lee, Seungho
id: BB243B88-D767-11E9-B658-BC13E6697425
last_name: Lee
orcid: 0000-0002-6962-8598
citation:
ama: Lee S. Nanoparticle-based precursors toward advanced crystalline inorganic
solids. 2025. doi:10.15479/AT-ISTA-20415
apa: Lee, S. (2025). Nanoparticle-based precursors toward advanced crystalline
inorganic solids. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20415
chicago: Lee, Seungho. “Nanoparticle-Based Precursors toward Advanced Crystalline
Inorganic Solids.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20415.
ieee: S. Lee, “Nanoparticle-based precursors toward advanced crystalline inorganic
solids,” Institute of Science and Technology Austria, 2025.
ista: Lee S. 2025. Nanoparticle-based precursors toward advanced crystalline inorganic
solids. Institute of Science and Technology Austria.
mla: Lee, Seungho. Nanoparticle-Based Precursors toward Advanced Crystalline
Inorganic Solids. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20415.
short: S. Lee, Nanoparticle-Based Precursors toward Advanced Crystalline Inorganic
Solids, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-10-01T09:04:00Z
date_published: 2025-10-01T00:00:00Z
date_updated: 2026-04-07T11:52:32Z
day: '01'
ddc:
- '540'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaIb
doi: 10.15479/AT-ISTA-20415
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file_date_updated: 2025-10-07T08:57:14Z
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language:
- iso: eng
month: '10'
oa_version: Published Version
page: '144'
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
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relation: part_of_dissertation
status: public
- id: '12237'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Loredana
full_name: Protesescu, Loredana
last_name: Protesescu
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
title: Nanoparticle-based precursors toward advanced crystalline inorganic solids
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20425'
abstract:
- lang: eng
text: Ultraviolet (UV) radiation from accreting black holes ionizes the intergalactic
gas around early quasars, carving out highly ionized bubbles in their surroundings.
Any changes in a quasar’s luminosity are therefore predicted to produce outward-propagating
ionization gradients, affecting the Lyα absorption opacity near the quasar’s systemic
redshift. This “proximity effect” is well-documented in rest-UV quasar spectra
but only provides a one-dimensional probe along our line of sight. Here we present
deep spectroscopic observations with the James Webb Space Telescope (JWST) of
galaxies in the background of a superluminous quasar at zQSO ≈ 6.3, which reveal
the quasar’s “light echo” with Lyα tomography in the transverse direction. This
transverse proximity effect is detected for the first time toward multiple galaxy
sightlines, allowing us to map the extent and geometry of the quasar’s ionization
cone. We obtain constraints on the orientation and inclination of the cone, as
well as an upper limit on the obscured solid angle fraction of fobsc < 91%. Additionally,
we find a timescale of the quasar’s UV radiation of tqso = 10^5.6+0.1-0.3 yr,
which is significantly shorter than would be required to build up the central
supermassive black hole (SMBH) with conventional growth models, but is consistent
with independent measurements of the quasars’ duty cycle. Our inferred obscured
fraction disfavors a scenario where short quasar lifetimes can be explained exclusively
by geometric obscuration, and instead supports the idea that radiatively inefficient
accretion or growth in initially heavily enshrouded cocoons plays a pivotal role
in early SMBH growth. Our results pave the way for novel studies of quasars’ ionizing
geometries and radiative histories at early cosmic times.
acknowledgement: "This work is based on observations made with the NASA/ESA/CSA James
Webb Space Telescope. The data were obtained from the Mikulski Archive for Space
Telescopes at the Space Telescope Science Institute, which is operated by the Association
of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127
for JWST. These observations are associated with programs #1243 and #4713.\r\n\r\nAll
of the data presented in this Letter were obtained from the Mikulski Archive for
Space Telescopes (MAST) at the Space Telescope Science Institute. The specific observations
analyzed can be accessed via doi:10.17909/w7hm-qb39.\r\nJ.M. is supported by the
European Union (ERC, AGENTS, 101076224)."
article_number: L40
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Anna Christina
full_name: Eilers, Anna Christina
last_name: Eilers
- first_name: Minghao
full_name: Yue, Minghao
last_name: Yue
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Joseph F.
full_name: Hennawi, Joseph F.
last_name: Hennawi
- first_name: Frederick B.
full_name: Davies, Frederick B.
last_name: Davies
- first_name: Robert A.
full_name: Simcoe, Robert A.
last_name: Simcoe
- first_name: Richard
full_name: Teague, Richard
last_name: Teague
- first_name: Rongmon
full_name: Bordoloi, Rongmon
last_name: Bordoloi
- first_name: Gabriel
full_name: Brammer, Gabriel
last_name: Brammer
- first_name: Yi
full_name: Kang, Yi
last_name: Kang
- first_name: Daichi
full_name: Kashino, Daichi
last_name: Kashino
- first_name: Ruari
full_name: Mackenzie, Ruari
last_name: Mackenzie
- first_name: Rohan P.
full_name: Naidu, Rohan P.
last_name: Naidu
- first_name: Benjamín
full_name: Navarrete, Benjamín
id: aa14a535-50c9-11ef-b52e-e0c373d10148
last_name: Navarrete
citation:
ama: Eilers AC, Yue M, Matthee JJ, et al. The light echo of a high-redshift quasar
mapped with Lyα tomography. The Astrophysical Journal Letters. 2025;991(2).
doi:10.3847/2041-8213/ae057a
apa: Eilers, A. C., Yue, M., Matthee, J. J., Hennawi, J. F., Davies, F. B., Simcoe,
R. A., … Navarrete, B. (2025). The light echo of a high-redshift quasar mapped
with Lyα tomography. The Astrophysical Journal Letters. IOP Publishing.
https://doi.org/10.3847/2041-8213/ae057a
chicago: Eilers, Anna Christina, Minghao Yue, Jorryt J Matthee, Joseph F. Hennawi,
Frederick B. Davies, Robert A. Simcoe, Richard Teague, et al. “The Light Echo
of a High-Redshift Quasar Mapped with Lyα Tomography.” The Astrophysical Journal
Letters. IOP Publishing, 2025. https://doi.org/10.3847/2041-8213/ae057a.
ieee: A. C. Eilers et al., “The light echo of a high-redshift quasar mapped
with Lyα tomography,” The Astrophysical Journal Letters, vol. 991, no.
2. IOP Publishing, 2025.
ista: Eilers AC, Yue M, Matthee JJ, Hennawi JF, Davies FB, Simcoe RA, Teague R,
Bordoloi R, Brammer G, Kang Y, Kashino D, Mackenzie R, Naidu RP, Navarrete B.
2025. The light echo of a high-redshift quasar mapped with Lyα tomography. The
Astrophysical Journal Letters. 991(2), L40.
mla: Eilers, Anna Christina, et al. “The Light Echo of a High-Redshift Quasar Mapped
with Lyα Tomography.” The Astrophysical Journal Letters, vol. 991, no.
2, L40, IOP Publishing, 2025, doi:10.3847/2041-8213/ae057a.
short: A.C. Eilers, M. Yue, J.J. Matthee, J.F. Hennawi, F.B. Davies, R.A. Simcoe,
R. Teague, R. Bordoloi, G. Brammer, Y. Kang, D. Kashino, R. Mackenzie, R.P. Naidu,
B. Navarrete, The Astrophysical Journal Letters 991 (2025).
date_created: 2025-10-05T22:01:35Z
date_published: 2025-09-25T00:00:00Z
date_updated: 2026-02-16T12:44:42Z
day: '25'
ddc:
- '520'
department:
- _id: JoMa
- _id: GradSch
doi: 10.3847/2041-8213/ae057a
external_id:
arxiv:
- '2509.05417'
isi:
- '001581023000001'
file:
- access_level: open_access
checksum: 3cb8099b9a915755164e5675b33f8a03
content_type: application/pdf
creator: dernst
date_created: 2025-10-13T09:25:12Z
date_updated: 2025-10-13T09:25:12Z
file_id: '20461'
file_name: 2025_AstrophysicalJour_Eilers.pdf
file_size: 23585591
relation: main_file
success: 1
file_date_updated: 2025-10-13T09:25:12Z
has_accepted_license: '1'
intvolume: ' 991'
isi: 1
issue: '2'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
grant_number: '101076224'
name: Young galaxies as tracers and agents of cosmic reionization
publication: The Astrophysical Journal Letters
publication_identifier:
eissn:
- 2041-8213
issn:
- 2041-8205
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: The light echo of a high-redshift quasar mapped with Lyα tomography
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 991
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '20454'
abstract:
- lang: eng
text: "Context. γ Dor stars are ideal targets for studies of the innermost dynamical
properties of stars, due to their rich asteroseismic spectrum of gravity modes.
Integrating internal magnetism to the picture appears as the next milestone of
detailed asteroseismic studies, for its prime importance on stellar evolution.
The inertial dip in prograde dipole modes period-spacing pattern of γ Dors stands
out as a unique window on the convective core structure and dynamics. Recent studies
have highlighted the dependence of the dip structure on core density stratification,
the contrast of the near-core Brunt-Väisälä frequency and rotation rate, as well
as the core-to-near-core differential rotation. In addition, the effect of envelope
magnetism has been derived on low-frequency magneto-gravito-inertial waves.\r\n\r\nAims.
We revisited the inertial dip formation including core and envelope magnetism,
and explored the probing power of this feature on dynamo-generated core fields.\r\n\r\nMethods.
We considered as a first step a toroidal magnetic field with a bi-layer (core
and envelope) Alfvén frequency. This configuration allowed us to revisit the coupling
problem using our knowledge on both core magneto-inertial modes and envelope magneto-gravito-inertial
modes. Using this configuration, we were able to stay in an analytical framework
to exhibit the magnetic effects on the inertial dip shape and location. This configuration
allowed a laboratory to be set up that moves us towards the comprehension of magnetic
effects on the dip structure.\r\n\r\nResults. We show a shift of the inertial
dip towards lower spin parameter values and a thinner dip with increasing core
magnetic field’s strength, quite similar to the signature of differential rotation.
The magnetic effects become sizeable when the ratio of the magnetic to the Coriolis
effects is high enough. We explored the potential degeneracy of the magnetic effects
with differential rotation. We studied the detectability of core magnetism, considering
both observational constraints on the periods of the modes and potential gravito-inertial
mode suppression."
acknowledgement: 'We thank the referee for their comments and suggestions which allowed
us to improve the quality of this manuscript. L. Barrault and L. Bugnet gratefully
acknowledge support from the European Research Council (ERC) under the Horizon Europe
programme (Calcifer; Starting Grant agreement N°101165631). S. Mathis acknowledges
support from the PLATO CNES grant at CEA/DAp. S. Mathis and J.S.G. Mombarg acknowledge
support from the European Research Council through HORIZON ERC SyG Grant 4D-STAR
101071505. While partially funded by the European Union, views and opinions expressed
are however those of the authors only and do not necessarily reflect those of the
European Union or the European Research Council. Neither the European Union nor
the granting authority can be held responsible for them. L. Barrault thanks T. Van
Reeth and C. Aerts for their invaluable teachings. The authors thank also the members
of the Asteroseismology and Stellar Dynamics group of the Institute of Science and
Technology Austria (ISTA) for very useful discussion: A. Cristea, L. Einramhof,
K. M. Smith, S. Torres.'
article_number: A253
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Lucas
full_name: Barrault, Lucas
id: 4471a8fd-32c1-11ee-a9a4-fb670d398f64
last_name: Barrault
- first_name: Lisa Annabelle
full_name: Bugnet, Lisa Annabelle
id: d9edb345-f866-11ec-9b37-d119b5234501
last_name: Bugnet
orcid: 0000-0003-0142-4000
- first_name: S.
full_name: Mathis, S.
last_name: Mathis
- first_name: J. S.G.
full_name: Mombarg, J. S.G.
last_name: Mombarg
citation:
ama: 'Barrault L, Bugnet LA, Mathis S, Mombarg JSG. Exploring the probing power
of γ Dor’s inertial dip for core magnetism: The case of a toroidal field. Astronomy
& Astrophysics. 2025;701. doi:10.1051/0004-6361/202555213'
apa: 'Barrault, L., Bugnet, L. A., Mathis, S., & Mombarg, J. S. G. (2025). Exploring
the probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal
field. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202555213'
chicago: 'Barrault, Lucas, Lisa Annabelle Bugnet, S. Mathis, and J. S.G. Mombarg.
“Exploring the Probing Power of γ Dor’s Inertial Dip for Core Magnetism: The Case
of a Toroidal Field.” Astronomy & Astrophysics. EDP Sciences, 2025.
https://doi.org/10.1051/0004-6361/202555213.'
ieee: 'L. Barrault, L. A. Bugnet, S. Mathis, and J. S. G. Mombarg, “Exploring the
probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal
field,” Astronomy & Astrophysics, vol. 701. EDP Sciences, 2025.'
ista: 'Barrault L, Bugnet LA, Mathis S, Mombarg JSG. 2025. Exploring the probing
power of γ Dor’s inertial dip for core magnetism: The case of a toroidal field.
Astronomy & Astrophysics. 701, A253.'
mla: 'Barrault, Lucas, et al. “Exploring the Probing Power of γ Dor’s Inertial Dip
for Core Magnetism: The Case of a Toroidal Field.” Astronomy & Astrophysics,
vol. 701, A253, EDP Sciences, 2025, doi:10.1051/0004-6361/202555213.'
short: L. Barrault, L.A. Bugnet, S. Mathis, J.S.G. Mombarg, Astronomy & Astrophysics
701 (2025).
corr_author: '1'
date_created: 2025-10-12T22:01:26Z
date_published: 2025-09-01T00:00:00Z
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day: '01'
ddc:
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department:
- _id: LiBu
- _id: GradSch
doi: 10.1051/0004-6361/202555213
external_id:
arxiv:
- '2507.00308'
isi:
- '001585834500002'
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- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
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grant_number: '101165631'
name: 'Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology'
publication: Astronomy & Astrophysics
publication_identifier:
eissn:
- 1432-0746
issn:
- 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Exploring the probing power of γ Dor''s inertial dip for core magnetism: The
case of a toroidal field'
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acknowledgement: "The work presented in this Thesis was carried out at the Institute
of Science and Technology\r\nAustria (ISTA), and was supported by the Austrian Science
Fund (FWF) [10.55776/P37131].\r\nI would like to thank the Scientific Service Units
(SSU) of ISTA for the provided resources,\r\nspecifically the Imaging and Optics
Facility (IOF), the Lab Support Facility (LSF), and the\r\nPre-Clinical Facility
(PCF) team, specifically Sonja Haslinger, Claudia Gold, and Michael\r\nSchunn, for
mouse colony management and support. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Florianne E
full_name: Miteva, Florianne E
id: 3526230C-F248-11E8-B48F-1D18A9856A87
last_name: Miteva
citation:
ama: Miteva FE. The role of cyclooxygenase 1 on microglial response to inflammatory
stressors. 2025. doi:10.15479/AT-ISTA-20467
apa: Miteva, F. E. (2025). The role of cyclooxygenase 1 on microglial response
to inflammatory stressors. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20467
chicago: Miteva, Florianne E. “The Role of Cyclooxygenase 1 on Microglial Response
to Inflammatory Stressors.” Institute of Science and Technology Austria, 2025.
https://doi.org/10.15479/AT-ISTA-20467.
ieee: F. E. Miteva, “The role of cyclooxygenase 1 on microglial response to inflammatory
stressors,” Institute of Science and Technology Austria, 2025.
ista: Miteva FE. 2025. The role of cyclooxygenase 1 on microglial response to inflammatory
stressors. Institute of Science and Technology Austria.
mla: Miteva, Florianne E. The Role of Cyclooxygenase 1 on Microglial Response
to Inflammatory Stressors. Institute of Science and Technology Austria, 2025,
doi:10.15479/AT-ISTA-20467.
short: F.E. Miteva, The Role of Cyclooxygenase 1 on Microglial Response to Inflammatory
Stressors, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-10-14T10:24:41Z
date_published: 2025-10-14T00:00:00Z
date_updated: 2026-05-20T06:37:12Z
day: '14'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: SaSi
doi: 10.15479/AT-ISTA-20467
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file_date_updated: 2025-10-23T11:33:06Z
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language:
- iso: eng
month: '10'
oa_version: Published Version
page: '99'
project:
- _id: 7be82147-9f16-11ee-852c-f44682d73140
grant_number: P37131
name: Dissecting the morpho-functional relationship of microglia
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '19566'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Sandra
full_name: Siegert, Sandra
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
title: The role of cyclooxygenase 1 on microglial response to inflammatory stressors
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20485'
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: "I would also like to acknowledge the funding that I received from
the European Union’s\r\nHorizon 2020 research and Innovation programme under the
Marie Sklodowska-Curie\r\nGrant Agreement No. 665385. This work would not have been
possible without the contribution and support of people\r\nbehind the scientific
service units at ISTA: the Life Science Facility (LSF), Imaging and\r\nOptics Facility
(IOF), the Bioinformatics Unit, Protein Services Unit and\r\nElectrophysiology Unit.
I would also like to recognize the work of people at the Vienna\r\nBiocenter (VBC)
Mass Spectrometry Facility, particularly Markus Hartl and WeiQiang\r\nChen. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Michaela
full_name: Misova, Michaela
id: 495A3C32-F248-11E8-B48F-1D18A9856A87
last_name: Misova
orcid: 0000-0003-2427-6856
citation:
ama: Misova M. Dissecting gap junction biology using the C. elegans nervous system.
2025. doi:10.15479/AT-ISTA-20485
apa: Misova, M. (2025). Dissecting gap junction biology using the C. elegans
nervous system. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20485
chicago: Misova, Michaela. “Dissecting Gap Junction Biology Using the C. Elegans
Nervous System.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20485.
ieee: M. Misova, “Dissecting gap junction biology using the C. elegans nervous system,”
Institute of Science and Technology Austria, 2025.
ista: Misova M. 2025. Dissecting gap junction biology using the C. elegans nervous
system. Institute of Science and Technology Austria.
mla: Misova, Michaela. Dissecting Gap Junction Biology Using the C. Elegans Nervous
System. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20485.
short: M. Misova, Dissecting Gap Junction Biology Using the C. Elegans Nervous System,
Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-10-17T16:15:09Z
date_published: 2025-10-23T00:00:00Z
date_updated: 2026-04-07T11:54:00Z
day: '23'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaDe
doi: 10.15479/AT-ISTA-20485
ec_funded: 1
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file_date_updated: 2025-11-06T11:08:06Z
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language:
- iso: eng
month: '10'
oa_version: Published Version
page: '155'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication_identifier:
isbn:
- 978-3-99078-068-8
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
title: Dissecting gap junction biology using the C. elegans nervous system
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type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20551'
abstract:
- lang: eng
text: "The space of codimension-2 shapes, such as curves in 3D and surfaces in 4D,
is an infinite-dimensional manifold. This thesis explores geometric structures
and dynamics on this space, with emphasis on their implications for physics, particularly
hydrodynamics.\r\n\r\nOur investigation ranges from theoretical studies of infinite-dimensional
symplectic and prequantum geometry to numerical computation of the time evolution
of shapes. The thesis presents four main contributions.\r\n\r\nIn the first part,
we introduce implicit representations of codimension-2 shapes using a class of
complex-valued functions, and prove that the space of these implicit representations
forms a prequantum bundle over the codimension-2 shape space. This reveals a new
geometric interpretation of the canonical symplectic structure on the codimension-2
shape space.\r\n\r\nIn the second part, we use implicit representations to develop
a simulation method for the dynamics of space curves. To handle chaotic systems
such as vortex filaments in hydrodynamics, we exploit the infinite degrees of
freedom, hidden in both the configuration and dynamics of implicit representations.\r\n\r\nIn
the third part, we introduce new symplectic structures on the space of space curves,
which generalize the only previously known symplectic structure on this space,
allowing for new Hamiltonian dynamics of space curves.\r\n\r\nIn the fourth part,
we apply a symplectic viewpoint to a differential geometric problem with practical
applications. We derive a new area formula for spherical polygons via prequantization. "
acknowledged_ssus:
- _id: CampIT
acknowledgement: "Projects contained in this thesis were financially supported in
part by the\r\nEuropean Research Council with grants 1. ERC Consolidator Grant 101045083
CoDiNA,\r\nand 2. the European Union’s Horizon 2020 research and innovation programme
under grant\r\nagreement No. 638176."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Sadashige
full_name: Ishida, Sadashige
id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
last_name: Ishida
orcid: 0000-0002-3121-3100
citation:
ama: Ishida S. Symplectic-prequantum structures and dynamics on the codimension-2
shape space. 2025. doi:10.15479/AT-ISTA-20551
apa: Ishida, S. (2025). Symplectic-prequantum structures and dynamics on the
codimension-2 shape space. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20551
chicago: Ishida, Sadashige. “Symplectic-Prequantum Structures and Dynamics on the
Codimension-2 Shape Space.” Institute of Science and Technology Austria, 2025.
https://doi.org/10.15479/AT-ISTA-20551.
ieee: S. Ishida, “Symplectic-prequantum structures and dynamics on the codimension-2
shape space,” Institute of Science and Technology Austria, 2025.
ista: Ishida S. 2025. Symplectic-prequantum structures and dynamics on the codimension-2
shape space. Institute of Science and Technology Austria.
mla: Ishida, Sadashige. Symplectic-Prequantum Structures and Dynamics on the
Codimension-2 Shape Space. Institute of Science and Technology Austria, 2025,
doi:10.15479/AT-ISTA-20551.
short: S. Ishida, Symplectic-Prequantum Structures and Dynamics on the Codimension-2
Shape Space, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-10-27T10:28:52Z
date_published: 2025-10-31T00:00:00Z
date_updated: 2026-04-07T12:02:23Z
day: '31'
ddc:
- '516'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ChWo
doi: 10.15479/AT-ISTA-20551
ec_funded: 1
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month: '10'
oa: 1
oa_version: Published Version
page: '141'
project:
- _id: 2533E772-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '638176'
name: 'Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large
Scales'
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
grant_number: '101045083'
name: Computational Discovery of Numerical Algorithms for Animation and Simulation
of Natural Phenomena
publication_identifier:
isbn:
- 978-3-99078-070-1
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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relation: part_of_dissertation
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status: public
- id: '20580'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
- first_name: Albert
full_name: Chern, Albert
last_name: Chern
title: Symplectic-prequantum structures and dynamics on the codimension-2 shape space
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type: dissertation
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...
---
OA_place: publisher
_id: '20575'
abstract:
- lang: eng
text: "This thesis deals with eigenvalue and eigenvector universality results for
random matrix ensembles equipped with non-trivial spatial structure. We consider
both mean-field models with a general variance profile (Wigner-type matrices)
and correlation structure (correlated matrices) among the entries, as well as
non-mean-field random band matrices with bandwidth W >> N^(1/2).\r\n\r\nTo extract
the universal properties of random matrix spectra and eigenvectors, we obtain
concentration estimates for their resolvent, the local laws, which generalize
the celebrated Wigner semicircle law for a broad class of random matrices to much
finer spectral scales. The local laws hold for both a single resolvent as well
as for products of multiple resolvents, known as resolvent chains, and express
the remarkable approximately-deterministic behavior of these objects down to the
microscopic scale.\r\n\r\nOur primary tool for establishing the local laws is
the dynamical Zigzag strategy, which we develop in the setting of spatially-inhomogeneous
random matrices. Our proof method systematically addresses the challenges arising
from non-trivial spatial structures and is robust to all types of singularities
in the spectrum, as we demonstrate in the correlated setting. Furthermore, we
incorporate the analysis of the deterministic resolvent chain approximations into
the dynamical framework of the Zigzag strategy, synthesizing a unified toolkit
for establishing multi-resolvent local laws.\r\n\r\nUsing these methods, we prove
complete eigenvector delocalization, the Eigenstate Thermalization Hypothesis,
and Wigner-Dyson universality in the bulk for random band matrices down to the
optimal bandwidth W >> N^(1/2). For mean-field ensembles, we establish universality
of local eigenvalue statistics at the cups for random matrices with correlated
entries, and the Eigenstate Thermalization Hypothesis for Wigner-type matrices
in the bulk of the spectrum.\r\n\r\nFinally, this thesis also contains other applications
of the multi-resolvent local laws to spatially-inhomogeneous random matrices,
obtained prior to the development of the Zigzag strategy. In particular, we provide
a complete analysis of mesoscopic linear-eigenvalue statistics of Wigner-type
matrices in all spectral regimes, including the novel cusps, and rigorously establish
the prethermalization phenomenon for deformed Wigner matrices.\r\n\r\nThe main
body of this thesis consists of seven research papers (listed on page xi), each
presented in a separate chapter with its own introduction and all relevant context,
suitable to be read independently. We ask the reader’s indulgence for the repetitions
in the historical overviews and other minor redundancies that remain among the
chapters as a result. The overall Introduction, preceding the chapters, provides
a condensed, informal summary of the main ideas and concepts at the core of these
works.\r\n"
acknowledgement: "The work comprising this thesis was supported by the ERC Advanced
Grant \"RMTBeyond\"\r\nNo.101020331 awarded to my advisor."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Volodymyr
full_name: Riabov, Volodymyr
id: 1949f904-edfb-11eb-afb5-e2dfddabb93b
last_name: Riabov
citation:
ama: Riabov V. Universality in random matrices with spatial structure. 2025. doi:10.15479/AT-ISTA-20575
apa: Riabov, V. (2025). Universality in random matrices with spatial structure.
Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20575
chicago: Riabov, Volodymyr. “Universality in Random Matrices with Spatial Structure.”
Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20575.
ieee: V. Riabov, “Universality in random matrices with spatial structure,” Institute
of Science and Technology Austria, 2025.
ista: Riabov V. 2025. Universality in random matrices with spatial structure. Institute
of Science and Technology Austria.
mla: Riabov, Volodymyr. Universality in Random Matrices with Spatial Structure.
Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20575.
short: V. Riabov, Universality in Random Matrices with Spatial Structure, Institute
of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-10-29T19:12:24Z
date_published: 2025-11-03T00:00:00Z
date_updated: 2026-04-07T12:32:20Z
day: '3'
ddc:
- '515'
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: LaEr
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ec_funded: 1
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month: '11'
oa: 1
oa_version: Published Version
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project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
call_identifier: H2020
grant_number: '101020331'
name: Random matrices beyond Wigner-Dyson-Mehta
publication_identifier:
isbn:
- 978-3-99078-064-0
issn:
- 2663-337X
publication_status: published
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status: public
supervisor:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
title: Universality in random matrices with spatial structure
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user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
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abstract:
- lang: eng
text: We prove that a very general class of $N\times N$ Hermitian random band matrices
is in the delocalized phase when the band width $W$ exceeds the critical threshold,
$W\gg \sqrt{N}$. In this regime, we show that, in the bulk spectrum, the eigenfunctions
are fully delocalized, the eigenvalues follow the universal Wigner-Dyson statistics,
and quantum unique ergodicity holds for general diagonal observables with an optimal
convergence rate. Our results are valid for general variance profiles, arbitrary
single entry distributions, in both real-symmetric and complex-Hermitian symmetry
classes. In particular, our work substantially generalizes the recent breakthrough
result of Yau and Yin [arXiv:2501.01718], obtained for a specific complex Hermitian
Gaussian block band matrix. The main technical input is the optimal multi-resolvent
local laws -- both in the averaged and fully isotropic form. We also generalize
the $\sqrtη$-rule from [arXiv:2012.13215] to exploit the additional effect of
traceless observables. Our analysis is based on the zigzag strategy, complemented
with a new global-scale estimate derived using the static version of the master
inequalities, while the zig-step and the a priori estimates on the deterministic
approximations are proven dynamically.
acknowledgement: " Supported by the ERC\r\nAdvanced Grant ”RMTBeyond” No. 101020331."
article_processing_charge: No
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Volodymyr
full_name: Riabov, Volodymyr
id: 1949f904-edfb-11eb-afb5-e2dfddabb93b
last_name: Riabov
citation:
ama: Erdös L, Riabov V. The zigzag strategy for random band matrices. arXiv.
doi:10.48550/ARXIV.2506.06441
apa: Erdös, L., & Riabov, V. (n.d.). The zigzag strategy for random band matrices.
arXiv. https://doi.org/10.48550/ARXIV.2506.06441
chicago: Erdös, László, and Volodymyr Riabov. “The Zigzag Strategy for Random Band
Matrices.” ArXiv, n.d. https://doi.org/10.48550/ARXIV.2506.06441.
ieee: L. Erdös and V. Riabov, “The zigzag strategy for random band matrices,” arXiv.
.
ista: Erdös L, Riabov V. The zigzag strategy for random band matrices. arXiv, 10.48550/ARXIV.2506.06441.
mla: Erdös, László, and Volodymyr Riabov. “The Zigzag Strategy for Random Band Matrices.”
ArXiv, doi:10.48550/ARXIV.2506.06441.
short: L. Erdös, V. Riabov, ArXiv (n.d.).
corr_author: '1'
date_created: 2025-10-29T19:09:03Z
date_published: 2025-06-06T00:00:00Z
date_updated: 2026-04-07T12:32:19Z
day: '06'
department:
- _id: GradSch
- _id: LaEr
doi: 10.48550/ARXIV.2506.06441
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2506.06441
month: '06'
oa: 1
oa_version: Preprint
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
call_identifier: H2020
grant_number: '101020331'
name: Random matrices beyond Wigner-Dyson-Mehta
publication: arXiv
publication_status: draft
related_material:
record:
- id: '20575'
relation: dissertation_contains
status: public
status: public
title: The zigzag strategy for random band matrices
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: repository
_id: '20580'
abstract:
- lang: eng
text: This paper explores the geometry of the space of codimension-2 submanifolds.
We implicitly represent these submanifolds by a class of complex-valued functions.
This reveals a prequantum bundle structure over the space of submanifolds, equipped
with the well-known Marsden-Weinstein symplectic structure. This bundle allows
a new physical interpretation of the Marsden-Weinstein structure as the curvature
of a connection form, which measures the average of volumes swept by the deformation
of the S^1-family of hypersurfaces, defined as the phases of a complex function
implicitly representing a submanifold.
article_processing_charge: No
arxiv: 1
author:
- first_name: Albert
full_name: Chern, Albert
last_name: Chern
- first_name: Sadashige
full_name: Ishida, Sadashige
id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
last_name: Ishida
orcid: 0000-0002-3121-3100
citation:
ama: Chern A, Ishida S. Implicit representations of codimension-2 submanifolds and
their prequantum structure. arXiv. doi:10.48550/ARXIV.2507.11727
apa: Chern, A., & Ishida, S. (n.d.). Implicit representations of codimension-2
submanifolds and their prequantum structure. arXiv. https://doi.org/10.48550/ARXIV.2507.11727
chicago: Chern, Albert, and Sadashige Ishida. “Implicit Representations of Codimension-2
Submanifolds and Their Prequantum Structure.” ArXiv, n.d. https://doi.org/10.48550/ARXIV.2507.11727.
ieee: A. Chern and S. Ishida, “Implicit representations of codimension-2 submanifolds
and their prequantum structure,” arXiv. .
ista: Chern A, Ishida S. Implicit representations of codimension-2 submanifolds
and their prequantum structure. arXiv, 10.48550/ARXIV.2507.11727.
mla: Chern, Albert, and Sadashige Ishida. “Implicit Representations of Codimension-2
Submanifolds and Their Prequantum Structure.” ArXiv, doi:10.48550/ARXIV.2507.11727.
short: A. Chern, S. Ishida, ArXiv (n.d.).
corr_author: '1'
date_created: 2025-10-30T18:36:56Z
date_published: 2025-07-15T00:00:00Z
date_updated: 2026-04-07T12:02:23Z
day: '15'
department:
- _id: GradSch
- _id: ChWo
doi: 10.48550/ARXIV.2507.11727
external_id:
arxiv:
- '2507.11727'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2507.11727
month: '07'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
record:
- id: '20551'
relation: dissertation_contains
status: public
status: public
title: Implicit representations of codimension-2 submanifolds and their prequantum
structure
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20628'
abstract:
- lang: eng
text: "The realistic simulation of sand, soil, powders, rubble piles, and large
collections of rigid bodies is a common and important problem in the fields of
computer graphics, computational physics, and engineering. Direct simulation of
these individual bodies quickly becomes expensive, so we often approximate the
entire group as a continuum material that can be more easily computed using tools
for solving partial differential equations, like the material point method (MPM).
In this paper, we present a method for automatically extracting continuum material
properties from a collection of rigid\r\nbodies. We use numerical homogenization
with periodic boundary conditions to simulate an effectively infinite number of
rigid bodies in contact. We then record the effective stress-strain relationships
from these simulations and convert them into elastic properties and yield criteria
for the continuum simulations. Our experiments validate existing theoretical models
like the Mohr-Coulomb yield surface by extracting material behaviors from a collection
of spheres in contact. We further generalize these existing models to more exotic
materials derived from diverse and non-convex shapes. We\r\nobserve complicated
jamming behaviors from non-convex grains, and we introduce a new material model
for materials with extremely high levels of internal friction and cohesion. We
simulate these new continuum models using MPM with an improved return mapping
technique. The end result is a complete system for turning an input rigid body
simulation into an efficient continuum simulation with the same effective mechanical
properties."
acknowledgement: 'We thank the anonymous reviewers for their helpful comments, the
members of the Visual Computing Group at ISTA for their feedback and Gauthier Rousseau
for the insightful discussions. This research was supported by the Scientific Service
Units (SSU) of ISTA through resources provided by Scientific Computing and was funded
in part by the European Union (ERC-2021-COG 101045083 CoDiNA). '
article_number: '220'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Yi-Lu
full_name: Chen, Yi-Lu
id: 0b467602-dbcd-11ea-9d1d-ed480aa46b70
last_name: Chen
orcid: 0009-0005-0723-0655
- first_name: Mickaël
full_name: Ly, Mickaël
id: 6340d7f0-b48d-11eb-b10d-b7487e71d9f1
last_name: Ly
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
citation:
ama: Chen Y-L, Ly M, Wojtan C. Numerical homogenization of sand from grain-level
simulations. ACM Transactions on Graphics. 2025;44(6). doi:10.1145/3763344
apa: 'Chen, Y.-L., Ly, M., & Wojtan, C. (2025). Numerical homogenization of
sand from grain-level simulations. ACM Transactions on Graphics. Hong Kong,
China: Association for Computing Machinery. https://doi.org/10.1145/3763344'
chicago: Chen, Yi-Lu, Mickaël Ly, and Chris Wojtan. “Numerical Homogenization of
Sand from Grain-Level Simulations.” ACM Transactions on Graphics. Association
for Computing Machinery, 2025. https://doi.org/10.1145/3763344.
ieee: Y.-L. Chen, M. Ly, and C. Wojtan, “Numerical homogenization of sand from grain-level
simulations,” ACM Transactions on Graphics, vol. 44, no. 6. Association
for Computing Machinery, 2025.
ista: Chen Y-L, Ly M, Wojtan C. 2025. Numerical homogenization of sand from grain-level
simulations. ACM Transactions on Graphics. 44(6), 220.
mla: Chen, Yi-Lu, et al. “Numerical Homogenization of Sand from Grain-Level Simulations.”
ACM Transactions on Graphics, vol. 44, no. 6, 220, Association for Computing
Machinery, 2025, doi:10.1145/3763344.
short: Y.-L. Chen, M. Ly, C. Wojtan, ACM Transactions on Graphics 44 (2025).
conference:
end_date: 2025-12-18
location: Hong Kong, China
name: 'SIGGRAPH Asia: Conference and Exhibition on Computer Graphics and Interactive
Techniques in Asia'
start_date: 2025-12-15
corr_author: '1'
date_created: 2025-11-10T14:12:06Z
date_published: 2025-12-04T00:00:00Z
date_updated: 2025-12-09T14:53:32Z
day: '04'
ddc:
- '531'
- '006'
- '621'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1145/3763344
file:
- access_level: open_access
checksum: 4d30ff82314e76fe411c8f8195bb6040
content_type: application/pdf
creator: yichen
date_created: 2025-11-10T14:10:12Z
date_updated: 2025-11-10T14:10:12Z
file_id: '20629'
file_name: main_paper.pdf
file_size: 61708650
relation: main_file
success: 1
- access_level: open_access
checksum: f1b6df39487866044ca7ca899d044be7
content_type: application/pdf
creator: yichen
date_created: 2025-11-10T14:10:27Z
date_updated: 2025-11-10T14:10:27Z
file_id: '20630'
file_name: paper_supplemental.pdf
file_size: 6862285
relation: supplementary_material
- access_level: open_access
checksum: 04ec2a4866774673479cafe5b93d26bd
content_type: video/mp4
creator: yichen
date_created: 2025-11-10T14:10:44Z
date_updated: 2025-11-10T14:10:44Z
file_id: '20631'
file_name: main_video.mp4
file_size: 164079303
relation: supplementary_material
- access_level: open_access
checksum: 7495e8cbcf94eb49276b4730c5886914
content_type: video/mp4
creator: yichen
date_created: 2025-11-10T14:10:53Z
date_updated: 2025-11-10T14:10:53Z
file_id: '20632'
file_name: extra_video.mp4
file_size: 72234678
relation: supplementary_material
file_date_updated: 2025-11-10T14:10:53Z
has_accepted_license: '1'
intvolume: ' 44'
issue: '6'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nd/4.0/
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
grant_number: '101045083'
name: Computational Discovery of Numerical Algorithms for Animation and Simulation
of Natural Phenomena
publication: ACM Transactions on Graphics
publication_identifier:
eissn:
- 1557-7368
issn:
- 0730-0301
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: Numerical homogenization of sand from grain-level simulations
tmp:
image: /image/cc_by_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
short: CC BY-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 44
year: '2025'
...
---
APC_amount: 3599,50 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20646'
abstract:
- lang: eng
text: Describing general quantum many-body dynamics is a challenging task due to
the exponential growth of the Hilbert space with system size. The time-dependent
variational principle (TDVP) provides a powerful tool to tackle this task by projecting
quantum evolution onto a classical dynamical system within a variational manifold.
In classical systems, periodic orbits play a crucial role in understanding the
structure of the phase space and the long-term behavior of the system. However,
finding periodic orbits is generally difficult, and their existence and properties
in generic TDVP dynamics over matrix product states have remained largely unexplored.
In this work, we develop an algorithm to systematically identify and characterize
periodic orbits in TDVP dynamics. Applying our method to the periodically kicked
Ising model, we uncover both stable and unstable periodic orbits. We characterize
the Kolmogorov-Arnold-Moser tori in the vicinity of stable periodic orbits and
track the change of the periodic orbits as we modify the Hamiltonian parameters.
We observe that periodic orbits exist at any value of the coupling constant of
the kicked Ising model between prethermal and fully thermalizing regimes, but
their relevance to quantum dynamics and imprint on quantum eigenstates diminishes
as the system leaves the prethermal regime. Our results demonstrate that periodic
orbits provide valuable insights into the TDVP approximation of quantum many-body
evolution and establish a closer connection between quantum and classical chaos.
acknowledgement: We acknowledge useful discussions with C. Kollath, A. Green, and
D. Huse. E.P., M.L., and M.S. acknowledge support by the European Research Council
under the European Union’s Horizon 2020 research and innovation program (Grant Agreement
No. 850899). This research was funded in whole or in part by the Austrian Science
Fund (FWF) (Grant No. 10.55776/COE1). For open access purposes, the author has applied
a CC BY public copyright license to any author accepted manuscript version arising
from this submission. M.L. acknowledges support by the Deutsche Forschungsgemeinschaft
(DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC-2111—390814868.
This research was supported in part by National Science Foundation (NSF) Grant No.
PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP) and by the Erwin
Schrödinger International Institute for Mathematics and Physics (ESI).
article_number: '040333'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Elena
full_name: Petrova, Elena
id: 0ac84990-897b-11ed-a09c-f5abb56a4ede
last_name: Petrova
- first_name: Marko
full_name: Ljubotina, Marko
id: F75EE9BE-5C90-11EA-905D-16643DDC885E
last_name: Ljubotina
orcid: 0000-0003-0038-7068
- first_name: Gökhan
full_name: Yalniz, Gökhan
id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425
last_name: Yalniz
orcid: 0000-0002-8490-9312
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Petrova E, Ljubotina M, Yalniz G, Serbyn M. Finding periodic orbits in projected
quantum many-body dynamics. PRX Quantum. 2025;6(4). doi:10.1103/tldp-kvkd
apa: Petrova, E., Ljubotina, M., Yalniz, G., & Serbyn, M. (2025). Finding periodic
orbits in projected quantum many-body dynamics. PRX Quantum. American Physical
Society. https://doi.org/10.1103/tldp-kvkd
chicago: Petrova, Elena, Marko Ljubotina, Gökhan Yalniz, and Maksym Serbyn. “Finding
Periodic Orbits in Projected Quantum Many-Body Dynamics.” PRX Quantum.
American Physical Society, 2025. https://doi.org/10.1103/tldp-kvkd.
ieee: E. Petrova, M. Ljubotina, G. Yalniz, and M. Serbyn, “Finding periodic orbits
in projected quantum many-body dynamics,” PRX Quantum, vol. 6, no. 4. American
Physical Society, 2025.
ista: Petrova E, Ljubotina M, Yalniz G, Serbyn M. 2025. Finding periodic orbits
in projected quantum many-body dynamics. PRX Quantum. 6(4), 040333.
mla: Petrova, Elena, et al. “Finding Periodic Orbits in Projected Quantum Many-Body
Dynamics.” PRX Quantum, vol. 6, no. 4, 040333, American Physical Society,
2025, doi:10.1103/tldp-kvkd.
short: E. Petrova, M. Ljubotina, G. Yalniz, M. Serbyn, PRX Quantum 6 (2025).
corr_author: '1'
date_created: 2025-11-14T09:40:52Z
date_published: 2025-11-12T00:00:00Z
date_updated: 2026-05-20T07:59:04Z
day: '12'
ddc:
- '539'
department:
- _id: GradSch
- _id: BjHo
- _id: MaSe
doi: 10.1103/tldp-kvkd
ec_funded: 1
external_id:
arxiv:
- '2504.12472'
isi:
- '001616473700003'
file:
- access_level: open_access
checksum: 5d6d04ac518b4118405334e1ddc7a56d
content_type: application/pdf
creator: gyalniz
date_created: 2025-11-14T09:44:10Z
date_updated: 2025-11-14T09:44:10Z
file_id: '20647'
file_name: tldp-kvkd.pdf
file_size: 2504713
relation: main_file
success: 1
file_date_updated: 2025-11-14T09:44:10Z
has_accepted_license: '1'
intvolume: ' 6'
isi: 1
issue: '4'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '850899'
name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
call_identifier: FWF
name: FWF Open Access Fund
publication: PRX Quantum
publication_identifier:
eissn:
- 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: press_release
url: https://ista.ac.at/en/news/reaching-for-the-quantum-scars/
scopus_import: '1'
status: public
title: Finding periodic orbits in projected quantum many-body dynamics
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2025'
...
---
APC_amount: 1260 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20664'
abstract:
- lang: eng
text: Conference travel contributes to the climate footprint of academic research.
Here, we provide a quantitative estimate of the carbon emissions associated with
conference attendance by analyzing travel data from participants of 10 international
conferences in the field of magnetic resonance, namely EUROMAR, ENC and ICMRBS.
We find that attending a EUROMAR conference produces, on average, more than 1 t CO2 eq..
For the analyzed conferences outside Europe, the corresponding value is about
2–3 times higher, on average, with intercontinental trips amounting to up to 5 t.
We compare these conference-related emissions to other activities associated with
research and show that conference travel is a substantial portion of the total
climate footprint of a researcher in magnetic resonance. We explore several strategies
to reduce these emissions, including the impact of selecting conference venues
more strategically and the possibility of decentralized conferences. Through a
detailed comparison of train versus air travel – accounting for both direct and
infrastructure-related emissions – we demonstrate that train travel offers considerable
carbon savings. These data may provide a basis for strategic choices of future
conferences in the field and for individuals deciding on their conference attendance.
acknowledgement: 'First and foremost, we are grateful to the conference organizers
who have provided data, either in the form of tables or by pointing us to abstract
books. We thank the reviewers and the handling editor (Gottfried Otting) for the
careful reading and suggestions. This project emerged from an interactive course
about energy and climate, held at IST Austria by Jeroen Dobbelaere, Georgios Katsaros
and Paul Schanda. We are grateful to ISTA''s Graduate School for enabling this interdisciplinary
course and to all participating students. We thank the following persons for discussions
and/or comments about the manuscript: Helene Van Melckebeke, Mei Hong, Jeff Hoch,
Gottfried Otting and Matthias Ernst. For the preparation of the manuscript, AI tools
have been used, namely for finding relevant literature (ChatGPT) and for correcting
the text (Writefull, within Overleaf LaTeX).'
article_processing_charge: Yes
article_type: original
author:
- first_name: Lucky
full_name: Kapoor, Lucky
id: 84b9700b-15b2-11ec-abd3-831089e67615
last_name: Kapoor
orcid: 0000-0001-8319-2148
- first_name: Natalia
full_name: Ruzickova, Natalia
id: D2761128-D73D-11E9-A1BF-BA0DE6697425
last_name: Ruzickova
- first_name: Predrag
full_name: Zivadinovic, Predrag
id: 68AA0E5A-AFDA-11E9-9994-141DE6697425
last_name: Zivadinovic
- first_name: Valentin
full_name: Leitner, Valentin
id: 4c665ce3-0016-11ec-bea0-e44de7a4fa3d
last_name: Leitner
- first_name: Maria A
full_name: Sisak, Maria A
id: 44A03D04-AEA4-11E9-B225-EA2DE6697425
last_name: Sisak
- first_name: Cecelia N
full_name: Mweka, Cecelia N
id: 2a69ab4b-896a-11ed-bdf8-cb8641cf2b21
last_name: Mweka
- first_name: Jeroen A
full_name: Dobbelaere, Jeroen A
id: c15a5412-de82-11ed-b809-8dc1aa996e40
last_name: Dobbelaere
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: 'Kapoor L, Ruzickova N, Zivadinovic P, et al. Quantifying the carbon footprint
of conference travel: The case of NMR meetings. Magnetic Resonance. 2025;6(2):243-256.
doi:10.5194/mr-6-243-2025'
apa: 'Kapoor, L., Ruzickova, N., Zivadinovic, P., Leitner, V., Sisak, M. A., Mweka,
C. N., … Schanda, P. (2025). Quantifying the carbon footprint of conference travel:
The case of NMR meetings. Magnetic Resonance. Copernicus Publications.
https://doi.org/10.5194/mr-6-243-2025'
chicago: 'Kapoor, Lucky, Natalia Ruzickova, Predrag Zivadinovic, Valentin Leitner,
Maria A Sisak, Cecelia N Mweka, Jeroen A Dobbelaere, Georgios Katsaros, and Paul
Schanda. “Quantifying the Carbon Footprint of Conference Travel: The Case of NMR
Meetings.” Magnetic Resonance. Copernicus Publications, 2025. https://doi.org/10.5194/mr-6-243-2025.'
ieee: 'L. Kapoor et al., “Quantifying the carbon footprint of conference
travel: The case of NMR meetings,” Magnetic Resonance, vol. 6, no. 2. Copernicus
Publications, pp. 243–256, 2025.'
ista: 'Kapoor L, Ruzickova N, Zivadinovic P, Leitner V, Sisak MA, Mweka CN, Dobbelaere
JA, Katsaros G, Schanda P. 2025. Quantifying the carbon footprint of conference
travel: The case of NMR meetings. Magnetic Resonance. 6(2), 243–256.'
mla: 'Kapoor, Lucky, et al. “Quantifying the Carbon Footprint of Conference Travel:
The Case of NMR Meetings.” Magnetic Resonance, vol. 6, no. 2, Copernicus
Publications, 2025, pp. 243–56, doi:10.5194/mr-6-243-2025.'
short: L. Kapoor, N. Ruzickova, P. Zivadinovic, V. Leitner, M.A. Sisak, C.N. Mweka,
J.A. Dobbelaere, G. Katsaros, P. Schanda, Magnetic Resonance 6 (2025) 243–256.
corr_author: '1'
date_created: 2025-11-23T23:01:39Z
date_published: 2025-11-10T00:00:00Z
date_updated: 2026-06-10T08:45:11Z
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oa: 1
oa_version: Published Version
page: 243-256
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- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
publication: Magnetic Resonance
publication_identifier:
eissn:
- 2699-0016
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: research_data
url: https://ista.ac.at/en/news/carbon-footprint-of-conference-travel/
record:
- id: '20242'
relation: research_data
status: public
scopus_import: '1'
status: public
title: 'Quantifying the carbon footprint of conference travel: The case of NMR meetings'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2025'
...
---
OA_place: publisher
_id: '20737'
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: "I also want to thank ISTA and the Austrian Science Fund FWF SFB
F78 (F7805) for financially\r\nsupporting my research."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Raquel
full_name: Casado Polanco, Raquel
id: 15240fc1-dbcd-11ea-9d1d-ac5a786425fd
last_name: Casado Polanco
orcid: 0000-0001-8293-4568
citation:
ama: Casado Polanco R. Role of NOTCH signaling in radial glial progenitor lineage
progression. 2025. doi:10.15479/AT-ISTA-20737
apa: Casado Polanco, R. (2025). Role of NOTCH signaling in radial glial progenitor
lineage progression. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20737
chicago: Casado Polanco, Raquel. “Role of NOTCH Signaling in Radial Glial Progenitor
Lineage Progression.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20737.
ieee: R. Casado Polanco, “Role of NOTCH signaling in radial glial progenitor lineage
progression,” Institute of Science and Technology Austria, 2025.
ista: Casado Polanco R. 2025. Role of NOTCH signaling in radial glial progenitor
lineage progression. Institute of Science and Technology Austria.
mla: Casado Polanco, Raquel. Role of NOTCH Signaling in Radial Glial Progenitor
Lineage Progression. Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20737.
short: R. Casado Polanco, Role of NOTCH Signaling in Radial Glial Progenitor Lineage
Progression, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-12-09T09:04:18Z
date_published: 2025-12-09T00:00:00Z
date_updated: 2026-04-14T08:16:58Z
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ddc:
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degree_awarded: PhD
department:
- _id: GradSch
- _id: SiHi
doi: 10.15479/AT-ISTA-20737
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keyword:
- NOTCH
- radial glial progenitor
- lineage progression
- cortical development
language:
- iso: eng
month: '12'
oa_version: Published Version
page: '133'
project:
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
grant_number: F7805
name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
Mechanisms of Neural Stem Cell Lineage Progression
publication_identifier:
isbn:
- 978-3-99078-072-5
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
title: Role of NOTCH signaling in radial glial progenitor lineage progression
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20741'
abstract:
- lang: eng
text: "Life on Earth emerged when biomacromolecules were membrane-enclosed in a
confined space where many essential chemical reactions were more likely to happen
and thereby accelerate evolution. These kinds of membranes separated internal
reactions from the outside chaos while staying flexible so that those primordial
cells can move, adopt their shape and, most importantly, propagate. Such membrane
plasticity still remains a defining feature of all modern cell types. This remarkable
ability to change their shape is most prominently observed during their propagation
(i.e., cell division). Throughout division, a cell undergoes drastic change in
its shape, usually at the middle of the cell, pulling the two opposite membrane
sides inward, closer to each other, and, finally, culminating in pinching off
to separate the cell into two daughter cells. To achieve this, a cell needs to
employ a protein machinery, usually termed divisome, that can coordinate all necessary
intracellular processes with membrane remodelling and synthesis of other extracellular
structures that decorate a cell. The focus of this dissertation is a membrane-remodelling
FtsZ system that is present across all domains of life. FtsZ forms filaments that
further self-organize into ring-like structures at the cell septum and together
with other division proteins perform cell envelope synthesis and constriction.
However, there are still knowledge gaps in our mechanistic understanding of division
in both archaea and bacteria. My work presented in this dissertation centres around
a simple yet not well understood question: How is the divisome positioned correctly
at the mid-cell? To achieve the proper positioning, the divisome needs to (i)
be recruited to the mid-cell and (ii) localized orthogonally to the long cell
axis. I tackle these processes in two different systems by applying an in vitro
biochemical bottom-up reconstitution approach. I use purified components of Haloferax
volcanii and Escherichia coli divisome to explore how divisome is recruited to
the mid-cell in archaea and how the Z-ring positions orthogonally to the long
cell axis in bacteria, respectively. \r\n\r\nFirstly, I collaborate with archaeal
cell and structural biologists to explore the assembly of early division proteins
in two FtsZ-containing archaeon H. volcanii, a standard model system for understudied
archaeal organisms. I particularly address the hierarchy of interactions that
allow a tripartite complex formation (SepF-CdpB1-CdpB2) and how the hierarchy
of interactions ultimately leads to the recruitment of FtsZ filaments to the septum.
This part of work has been published in (Nußbaum et al., 2024). In collaboration
with evolutionary biologists, I shed light on ancient features that archaeal divisome
has retained to this day and also speculate on a property that it might have lost
during the course of evolution. \r\n\r\nNext, I switch my attention to E. coli
divisome. Particularly, I address the FtsZ’s intrinsic biophysical property that
drives the Z-ring diameter, and thereby the perpendicular orientation of the Z-ring
to the long cell axis based on suggested membrane curvature sensing mechanism
(Vanhille-Campos et al., 2024). This property allows formation of different Z-ring
diameters that match the variety of cell diameters present in prokaryotes. The
results showcase that the distribution of charged amino acids in the intrinsically
disordered linker at the C-terminus (CTL) of FtsZ is the major determining factor
of Z-ring diameter with inter-CTL interactions as an underlying mechanism. \r\n\r\nFinally,
I thoroughly explain the methodology I used to address the abovementioned projects,
and I finish with a discussion on how early archaeal divisome assembly and curvature
sensing mechanism in bacteria, at first sight unrelated topics, are interconnected
and important groundwork for both fundamental and translational research. "
acknowledged_ssus:
- _id: Bio
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Marko
full_name: Kojic, Marko
id: 73e7ecd4-dc85-11ea-9058-88a16394b160
last_name: Kojic
orcid: 0000-0001-7244-8128
citation:
ama: Kojic M. Towards understanding the assembly mechanisms of the Z-ring in Archaea
and Bacteria. 2025. doi:10.15479/AT-ISTA-20741
apa: Kojic, M. (2025). Towards understanding the assembly mechanisms of the Z-ring
in Archaea and Bacteria. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20741
chicago: Kojic, Marko. “Towards Understanding the Assembly Mechanisms of the Z-Ring
in Archaea and Bacteria.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20741.
ieee: M. Kojic, “Towards understanding the assembly mechanisms of the Z-ring in
Archaea and Bacteria,” Institute of Science and Technology Austria, 2025.
ista: Kojic M. 2025. Towards understanding the assembly mechanisms of the Z-ring
in Archaea and Bacteria. Institute of Science and Technology Austria.
mla: Kojic, Marko. Towards Understanding the Assembly Mechanisms of the Z-Ring
in Archaea and Bacteria. Institute of Science and Technology Austria, 2025,
doi:10.15479/AT-ISTA-20741.
short: M. Kojic, Towards Understanding the Assembly Mechanisms of the Z-Ring in
Archaea and Bacteria, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-12-09T13:08:11Z
date_published: 2025-12-09T00:00:00Z
date_updated: 2026-04-07T12:27:58Z
day: '09'
ddc:
- '572'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaLo
doi: 10.15479/AT-ISTA-20741
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file_id: '20774'
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file_size: 142876975
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creator: mkojic
date_created: 2025-12-10T13:09:38Z
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has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication_identifier:
isbn:
- 978-3-99078-073-2
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '15118'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Martin
full_name: Loose, Martin
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
title: Towards understanding the assembly mechanisms of the Z-ring in Archaea and
Bacteria
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '10045'
abstract:
- lang: eng
text: "Given a fixed finite metric space (V,μ), the {\\em minimum 0-extension problem},
denoted as 0-Ext[μ], is equivalent to the following optimization problem: minimize
function of the form minx∈Vn∑ifi(xi)+∑ijcijμ(xi,xj) where cij,cvi are given nonnegative
costs and fi:V→R are functions given by fi(xi)=∑v∈Vcviμ(xi,v). The computational
complexity of 0-Ext[μ] has been recently established by Karzanov and by Hirai:
if metric μ is {\\em orientable modular} then 0-Ext[μ] can be solved in polynomial
time, otherwise 0-Ext[μ] is NP-hard. To prove the tractability part, Hirai developed
a theory of discrete convex functions on orientable modular graphs generalizing
several known classes of functions in discrete convex analysis, such as L♮-convex
functions. We consider a more general version of the problem in which unary functions
fi(xi) can additionally have terms of the form cuv;iμ(xi,{u,v}) for {u,v}∈F, where
set F⊆(V2) is fixed. We extend the complexity classification above by providing
an explicit condition on (μ,F) for the problem to be tractable. In order to prove
the tractability part, we generalize Hirai's theory and define a larger class
of discrete convex functions. It covers, in particular, another well-known class
of functions, namely submodular functions on an integer lattice. Finally, we improve
the complexity of Hirai's algorithm for solving 0-Ext on orientable modular graphs.\r\n"
acknowledgement: We thank the anonymous reviewers for their careful reading of our
manuscript and their many insightful comments and suggestions. Open access funding
provided by Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Martin
full_name: Dvorak, Martin
id: 40ED02A8-C8B4-11E9-A9C0-453BE6697425
last_name: Dvorak
orcid: 0000-0001-5293-214X
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Dvorak M, Kolmogorov V. Generalized minimum 0-extension problem and discrete
convexity. Mathematical Programming. 2025;209:279-322. doi:10.1007/s10107-024-02064-5
apa: Dvorak, M., & Kolmogorov, V. (2025). Generalized minimum 0-extension problem
and discrete convexity. Mathematical Programming. Springer Nature. https://doi.org/10.1007/s10107-024-02064-5
chicago: Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension
Problem and Discrete Convexity.” Mathematical Programming. Springer Nature,
2025. https://doi.org/10.1007/s10107-024-02064-5.
ieee: M. Dvorak and V. Kolmogorov, “Generalized minimum 0-extension problem and
discrete convexity,” Mathematical Programming, vol. 209. Springer Nature,
pp. 279–322, 2025.
ista: Dvorak M, Kolmogorov V. 2025. Generalized minimum 0-extension problem and
discrete convexity. Mathematical Programming. 209, 279–322.
mla: Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem
and Discrete Convexity.” Mathematical Programming, vol. 209, Springer Nature,
2025, pp. 279–322, doi:10.1007/s10107-024-02064-5.
short: M. Dvorak, V. Kolmogorov, Mathematical Programming 209 (2025) 279–322.
corr_author: '1'
date_created: 2021-09-27T10:48:23Z
date_published: 2025-01-01T00:00:00Z
date_updated: 2025-05-19T13:52:10Z
day: '01'
ddc:
- '004'
department:
- _id: GradSch
- _id: VlKo
doi: 10.1007/s10107-024-02064-5
external_id:
arxiv:
- '2109.10203'
isi:
- '001176563300001'
file:
- access_level: open_access
checksum: 25d9bd490719b45eca84f4d93a06c69f
content_type: application/pdf
creator: dernst
date_created: 2025-04-16T09:36:08Z
date_updated: 2025-04-16T09:36:08Z
file_id: '19578'
file_name: 2025_MathProgramming_Dvorak.pdf
file_size: 839510
relation: main_file
success: 1
file_date_updated: 2025-04-16T09:36:08Z
has_accepted_license: '1'
intvolume: ' 209'
isi: 1
keyword:
- minimum 0-extension problem
- metric labeling problem
- discrete metric spaces
- metric extensions
- computational complexity
- valued constraint satisfaction problems
- discrete convex analysis
- L-convex functions
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 279-322
publication: Mathematical Programming
publication_identifier:
eissn:
- 1436-4646
issn:
- 0025-5610
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Generalized minimum 0-extension problem and discrete convexity
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 209
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '22120'
article_number: EGU25-17446
article_processing_charge: No
author:
- first_name: José M
full_name: Muñoz Hermosilla, José M
id: e1037a6d-646e-11ef-b402-e0ed9ab0901e
last_name: Muñoz Hermosilla
orcid: 0000-0002-1990-8508
- first_name: Evan
full_name: Miles, Evan
last_name: Miles
- first_name: Michael
full_name: McCarthy, Michael
id: 22a2674a-61ce-11ee-94b5-d18813baf16f
last_name: McCarthy
- first_name: Florian
full_name: Hardmeier, Florian
last_name: Hardmeier
- first_name: Juan Vicente
full_name: Melo Velasco, Juan Vicente
id: 2611dec0-b9c6-11ed-9bea-a81c2b17a549
last_name: Melo Velasco
- first_name: Guillaume
full_name: Jouvet, Guillaume
last_name: Jouvet
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
orcid: 0000-0002-5554-8087
citation:
ama: 'Muñoz Hermosilla JM, Miles E, McCarthy M, et al. Towards reconstructing debris
supply to reproduce the historic changes in debris extent at a Swiss glacier.
In: EGU General Assembly 2025. European Geosciences Union; 2025. doi:10.5194/egusphere-egu25-17446'
apa: 'Muñoz Hermosilla, J. M., Miles, E., McCarthy, M., Hardmeier, F., Melo Velasco,
J. V., Jouvet, G., & Pellicciotti, F. (2025). Towards reconstructing debris
supply to reproduce the historic changes in debris extent at a Swiss glacier.
In EGU General Assembly 2025. Vienna, Austria & Virtual: European Geosciences
Union. https://doi.org/10.5194/egusphere-egu25-17446'
chicago: Muñoz Hermosilla, José M, Evan Miles, Michael McCarthy, Florian Hardmeier,
Juan Vicente Melo Velasco, Guillaume Jouvet, and Francesca Pellicciotti. “Towards
Reconstructing Debris Supply to Reproduce the Historic Changes in Debris Extent
at a Swiss Glacier.” In EGU General Assembly 2025. European Geosciences
Union, 2025. https://doi.org/10.5194/egusphere-egu25-17446.
ieee: J. M. Muñoz Hermosilla et al., “Towards reconstructing debris supply
to reproduce the historic changes in debris extent at a Swiss glacier,” in EGU
General Assembly 2025, Vienna, Austria & Virtual, 2025.
ista: Muñoz Hermosilla JM, Miles E, McCarthy M, Hardmeier F, Melo Velasco JV, Jouvet
G, Pellicciotti F. 2025. Towards reconstructing debris supply to reproduce the
historic changes in debris extent at a Swiss glacier. EGU General Assembly 2025.
EGU General Assembly, EGU25-17446.
mla: Muñoz Hermosilla, José M., et al. “Towards Reconstructing Debris Supply to
Reproduce the Historic Changes in Debris Extent at a Swiss Glacier.” EGU General
Assembly 2025, EGU25-17446, European Geosciences Union, 2025, doi:10.5194/egusphere-egu25-17446.
short: J.M. Muñoz Hermosilla, E. Miles, M. McCarthy, F. Hardmeier, J.V. Melo Velasco,
G. Jouvet, F. Pellicciotti, in:, EGU General Assembly 2025, European Geosciences
Union, 2025.
conference:
end_date: 2025-05-02
location: Vienna, Austria & Virtual
name: EGU General Assembly
start_date: 2025-04-27
date_created: 2026-06-22T12:17:47Z
date_published: 2025-05-14T00:00:00Z
date_updated: 2026-07-02T06:41:43Z
day: '14'
ddc:
- '550'
department:
- _id: FrPe
- _id: GradSch
doi: 10.5194/egusphere-egu25-17446
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5194/egusphere-egu25-17446
month: '05'
oa: 1
oa_version: Published Version
publication: EGU General Assembly 2025
publication_status: published
publisher: European Geosciences Union
status: public
title: Towards reconstructing debris supply to reproduce the historic changes in debris
extent at a Swiss glacier
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference_abstract
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
_id: '21427'
abstract:
- lang: eng
text: While tumor malignancy has been extensively studied under the prism of genetic
and epigenetic heterogeneity, tumor cell states also critically depend on reciprocal
interactions with the microenvironment. This raises the hitherto untested possibility
that heterogeneity of the untransformed tumor stroma can actively fuel malignant
progression. As biological heterogeneity is inherently difficult to control, we
adopted a reductionist approach and let tumor cells invade micro-engineered environments
harboring obstacles with precision-controlled geometry. We find that not only
the presence of obstacles, but more surprisingly their spatial disorder, causes
a drastic shift from a collective to a single-cell mode of invasion – comparable
in strength to cadherin loss. Combining live-imaging and perturbation experiments
with minimal biophysical modeling, we demonstrate that cell detachments result
both from local geometrical constraints and a global integration of spatial disorder
over time. We show that different types of microenvironments map onto different
universality classes of invasion dynamics - homogeneous substrates follow Kardar–Parisi–Zhang
(KPZ) scaling, while disordered ones exhibit exponents consistent with KPZ with
quenched disorder (KPZq). Our findings highlight generic physical principles for
how the mode of cancer cell invasion depends on environmental heterogeneity, with
potential implications to understand tumor evolution in vivo.
acknowledgement: "European Research Council, https://ror.org/0472cxd90, 101071793\r\nAustrian
Academy of Sciences, 26360"
article_processing_charge: No
author:
- first_name: Zuzana
full_name: Dunajova, Zuzana
id: 4B39F286-F248-11E8-B48F-1D18A9856A87
last_name: Dunajova
- first_name: Saren
full_name: Tasciyan, Saren
id: 4323B49C-F248-11E8-B48F-1D18A9856A87
last_name: Tasciyan
orcid: 0000-0003-1671-393X
- first_name: Juraj
full_name: Majek, Juraj
id: 3e6d9473-f38e-11ec-8ae0-c4e05a8aa9e1
last_name: Majek
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: Erik
full_name: Sahai, Erik
last_name: Sahai
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Edouard B
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ama: Dunajova Z, Tasciyan S, Majek J, et al. Substrate heterogeneity promotes cancer
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apa: Dunajova, Z., Tasciyan, S., Majek, J., Merrin, J., Sahai, E., Sixt, M. K.,
& Hannezo, E. B. (n.d.). Substrate heterogeneity promotes cancer cell dissemination
through interface roughening. bioRxiv. https://doi.org/10.1101/2025.05.20.655037
chicago: Dunajova, Zuzana, Saren Tasciyan, Juraj Majek, Jack Merrin, Erik Sahai,
Michael K Sixt, and Edouard B Hannezo. “Substrate Heterogeneity Promotes Cancer
Cell Dissemination through Interface Roughening.” BioRxiv, n.d. https://doi.org/10.1101/2025.05.20.655037.
ieee: Z. Dunajova et al., “Substrate heterogeneity promotes cancer cell dissemination
through interface roughening,” bioRxiv. .
ista: Dunajova Z, Tasciyan S, Majek J, Merrin J, Sahai E, Sixt MK, Hannezo EB. Substrate
heterogeneity promotes cancer cell dissemination through interface roughening.
bioRxiv, 10.1101/2025.05.20.655037.
mla: Dunajova, Zuzana, et al. “Substrate Heterogeneity Promotes Cancer Cell Dissemination
through Interface Roughening.” BioRxiv, doi:10.1101/2025.05.20.655037.
short: Z. Dunajova, S. Tasciyan, J. Majek, J. Merrin, E. Sahai, M.K. Sixt, E.B.
Hannezo, BioRxiv (n.d.).
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https://doi.org/10.15479/AT-ISTA-20364.
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