---
OA_type: closed access
_id: '3940'
abstract:
- lang: eng
  text: Until recently little information was available on the molecular details of
    the extracellular matrix (ECM) of secondary lymphoid tissues. There is now growing
    evidence that these ECMs are unique structures, combining characteristics of basement
    membranes and interstitial or fibrillar matrices, resulting in scaffolds that
    are strong and highly flexible and, in certain secondary lymphoid compartments,
    also forming conduit networks for rapid fluid transport. This review will address
    the structural characteristics of the ECM of the murine spleen and its potential
    role as an organizer of immune cell compartments, with reference to the lymph
    node where relevant.
article_processing_charge: No
article_type: review
author:
- first_name: Zerina
  full_name: Lokmic, Zerina
  last_name: Lokmic
- first_name: Tim
  full_name: Lämmermann, Tim
  last_name: Lämmermann
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Susanna
  full_name: Cardell, Susanna
  last_name: Cardell
- first_name: Rupert
  full_name: Hallmann, Rupert
  last_name: Hallmann
- first_name: Lydia
  full_name: Sorokin, Lydia
  last_name: Sorokin
citation:
  ama: Lokmic Z, Lämmermann T, Sixt MK, Cardell S, Hallmann R, Sorokin L. The extracellular
    matrix of the spleen as a potential organizer of immune cell compartments. <i>Seminars
    in Immunology</i>. 2008;20(1):4-13. doi:<a href="https://doi.org/10.1016/j.smim.2007.12.009">10.1016/j.smim.2007.12.009</a>
  apa: Lokmic, Z., Lämmermann, T., Sixt, M. K., Cardell, S., Hallmann, R., &#38; Sorokin,
    L. (2008). The extracellular matrix of the spleen as a potential organizer of
    immune cell compartments. <i>Seminars in Immunology</i>. Academic Press. <a href="https://doi.org/10.1016/j.smim.2007.12.009">https://doi.org/10.1016/j.smim.2007.12.009</a>
  chicago: Lokmic, Zerina, Tim Lämmermann, Michael K Sixt, Susanna Cardell, Rupert
    Hallmann, and Lydia Sorokin. “The Extracellular Matrix of the Spleen as a Potential
    Organizer of Immune Cell Compartments.” <i>Seminars in Immunology</i>. Academic
    Press, 2008. <a href="https://doi.org/10.1016/j.smim.2007.12.009">https://doi.org/10.1016/j.smim.2007.12.009</a>.
  ieee: Z. Lokmic, T. Lämmermann, M. K. Sixt, S. Cardell, R. Hallmann, and L. Sorokin,
    “The extracellular matrix of the spleen as a potential organizer of immune cell
    compartments,” <i>Seminars in Immunology</i>, vol. 20, no. 1. Academic Press,
    pp. 4–13, 2008.
  ista: Lokmic Z, Lämmermann T, Sixt MK, Cardell S, Hallmann R, Sorokin L. 2008. The
    extracellular matrix of the spleen as a potential organizer of immune cell compartments.
    Seminars in Immunology. 20(1), 4–13.
  mla: Lokmic, Zerina, et al. “The Extracellular Matrix of the Spleen as a Potential
    Organizer of Immune Cell Compartments.” <i>Seminars in Immunology</i>, vol. 20,
    no. 1, Academic Press, 2008, pp. 4–13, doi:<a href="https://doi.org/10.1016/j.smim.2007.12.009">10.1016/j.smim.2007.12.009</a>.
  short: Z. Lokmic, T. Lämmermann, M.K. Sixt, S. Cardell, R. Hallmann, L. Sorokin,
    Seminars in Immunology 20 (2008) 4–13.
date_created: 2018-12-11T12:06:00Z
date_published: 2008-02-01T00:00:00Z
date_updated: 2026-05-29T09:29:25Z
day: '01'
doi: 10.1016/j.smim.2007.12.009
extern: '1'
external_id:
  pmid:
  - '18243017'
intvolume: '        20'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 4 - 13
pmid: 1
publication: Seminars in Immunology
publication_identifier:
  eissn:
  - 1096-3618
  issn:
  - 1044-5323
publication_status: published
publisher: Academic Press
publist_id: '2188'
status: public
title: The extracellular matrix of the spleen as a potential organizer of immune cell
  compartments
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 20
year: '2008'
...