@article{20755, abstract = {We report the development of a continuous flow approach to nitrogen atom insertion. The setup is modular, enabling the rapid optimization of reaction conditions for a wide range of substrates. The milder reaction conditions led to an improved substrate scope and functional group tolerance compared to batch conditions. The reactions can also be safely scaled up to preparative scale.}, author = {Moon, Sooyeon and Reisenbauer, Julia and Paschke, Ann-Sophie K. and Scotto, Alessandro and Terraneo, Luca and Brenner, Niklas and Lefebvre, Quentin and Fessard, Thomas C. and Morandi, Bill}, issn = {1364-548X}, journal = {Chemical Communications}, number = {87}, pages = {16993--16996}, publisher = {Royal Society of Chemistry}, title = {{Efficient optimization and synthesis of diverse azaarenes via nitrogen atom insertion under continuous flow conditions}}, doi = {10.1039/d5cc03194j}, volume = {61}, year = {2025}, } @article{20757, abstract = {We report the utilisation of an iodine(III) reagent to access α,β-unsaturated carbonyls from the corresponding silyl enol ethers and enol phosphates. The transformation can also be carried out in one pot, directly dehydrogenating carbonyls.}, author = {Botlik, Bence B. and Finkelstein, Patrick and Paschke, Ann-Sophie K. and Reisenbauer, Julia and Morandi, Bill}, issn = {1364-548X}, journal = {Chemical Communications}, number = {69}, pages = {9254--9257}, publisher = {Royal Society of Chemistry}, title = {{Versatile dehydrogenation of carbonyls enabled by an iodine(III) reagent}}, doi = {10.1039/d4cc02609h}, volume = {60}, year = {2024}, } @article{17869, abstract = {The formation of carbon–carbon bonds with transition metal reagents serves as a cornerstone of organic synthesis. Here, we show that the reactivity of an otherwise kinetically inert transition metal complex can be induced by an external electric field to affect a coupling reaction. These results highlight the importance of electric field effects in reaction chemistry and offers a new strategy to modulate organometallic reactivity.}, author = {Orchanian, Nicholas M. and Guizzo, Sophia and Steigerwald, Michael L. and Nuckolls, Colin and Venkataraman, Latha}, issn = {1364-548X}, journal = {Chemical Communications}, number = {90}, pages = {12556--12559}, publisher = {Royal Society of Chemistry}, title = {{Electric-field-induced coupling of aryl iodides with a nickel(0) complex}}, doi = {10.1039/d2cc03671a}, volume = {58}, year = {2022}, } @article{13353, abstract = {We show that the optical properties of indigo carmine can be modulated by encapsulation within a coordination cage. Depending on the host/guest molar ratio, the cage can predominantly encapsulate either one or two dye molecules. The 1 : 1 complex is fluorescent, unique for an indigo dye in an aqueous solution. We have also found that binding two dye molecules stabilizes a previously unknown conformation of the cage.}, author = {Yanshyna, Oksana and Avram, Liat and Shimon, Linda J. W. and Klajn, Rafal}, issn = {1364-548X}, journal = {Chemical Communications}, keywords = {Materials Chemistry, Metals and Alloys, Surfaces, Coatings and Films, General Chemistry, Ceramics and Composites, Electronic, Optical and Magnetic Materials, Catalysis}, number = {21}, pages = {3461--3464}, publisher = {Royal Society of Chemistry}, title = {{Coexistence of 1:1 and 2:1 inclusion complexes of indigo carmine}}, doi = {10.1039/d1cc07081a}, volume = {58}, year = {2022}, } @article{21823, abstract = {DFT calculations were used to find an optimal substitution site on the triene backbone of a donor–acceptor Stenhouse adduct photoswitch to tune the equillibrium and switching kinetics of DASA without modifying the donor and acceptor groups. Using this approach we demonstrate a new means to tuning DASA based photoswitches by increasing the energy of the closed form relative to the open form. To highlight the potential of this approach a new DASA derivative bearing a methyl substituent on the 5-position of the triene was synthesized and the effect of this substitution was studied using 1H NMR spectroscopy, time-dependent UV-Vis and solvatochromic analysis. The new DASA derivative shows a higher dark equillibrium, favoring the open form, and drastically faster thermal recovery than the unsubstituted derivative with the same donor and acceptor.}, author = {Peterson, Julie A. and Stricker, Friedrich J and Read de Alaniz, Javier}, issn = {1364-548X}, journal = {Chemical Communications}, number = {14}, pages = {2303--2306}, publisher = {Royal Society of Chemistry}, title = {{Improving the kinetics and dark equilibrium of donor-acceptor Stenhouse adduct by triene backbone design}}, doi = {10.1039/d1cc06235b}, volume = {58}, year = {2022}, } @article{17901, abstract = {A 1,1,2,2-tetrakis(4-aminophenyl)ethene with three paths of π-conjugation, linear-cis, linear-trans and a cross-conjugation, has been prepared. The molecule is able to bind to gold electrodes forming molecular junctions for single-molecule conductance measurements. Only two regimes of conduction are found experimentally. The modelling of the conductance allows to assign them to through-bond transmission in the linear case, while the cross-conjugated channel is further assisted by through-space transmission, partially alleviating the destructive quantum interference.}, author = {Medina Rivero, Samara and García Arroyo, Paloma and Li, Liang and Gunasekaran, Suman and Stuyver, Thijs and Mancheño, María José and Alonso, Mercedes and Venkataraman, Latha and Segura, José L. and Casado, Juan}, issn = {1364-548X}, journal = {Chemical Communications}, number = {5}, pages = {591--594}, publisher = {Royal Society of Chemistry}, title = {{Single-molecule conductance in a unique cross-conjugated tetra(aminoaryl)ethene}}, doi = {10.1039/d0cc07124b}, volume = {57}, year = {2021}, } @article{20765, abstract = {

A cascade Suzuki–Miyaura cross-coupling between two non-symmetrical coupling partners gave rise to 9,10-dihydrophenanthrenes with full site-selectivity. The choice of base was critical to facilitate the challenging coupling of the secondary boronate group.

}, author = {Willems, Suzanne and Toupalas, Georgios and Reisenbauer, Julia and Morandi, Bill}, issn = {1364-548X}, journal = {Chemical Communications}, number = {32}, pages = {3909--3912}, publisher = {Royal Society of Chemistry}, title = {{A site-selective and stereospecific cascade Suzuki–Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2′-dihalo 1,1′-biaryls}}, doi = {10.1039/d1cc00648g}, volume = {57}, year = {2021}, } @article{21082, abstract = {A novel chiral aromatic δ-amino acid building block was shown to fully induce handedness in quinoline oligoamide foldamers with the possibility of further increasing the bias by combining multiples of these units in the same sequence. Through its incorporation within the helix, both N- and C-termini are still accessible for further functionalisation.}, author = {Bindl, Daniel and Heinemann, Elisabeth and Mandal, Pradeep K and Huc, Ivan}, issn = {1364-548X}, journal = {Chemical Communications}, number = {46}, pages = {5662--5665}, publisher = {Royal Society of Chemistry}, title = {{Quantitative helix handedness bias through a single H vs. CH3 stereochemical differentiation}}, doi = {10.1039/d1cc01452h}, volume = {57}, year = {2021}, } @article{21100, abstract = {Using commercial screens for crystallization of biomolecules and taking advantage of the use of racemic crystallography allowed the production of X-ray quality single crystals and the elucidation at 1.08 Å resolution of the solid state structure of a difficult target: the complex between glucopyranose and a water soluble macrocyclic receptor equipped with dendritic multianionic solubilizing chains.}, author = {Mandal, Pradeep K and Kauffmann, Brice and Destecroix, Harry and Ferrand, Yann and Davis, Anthony P. and Huc, Ivan}, issn = {1364-548X}, journal = {Chemical Communications}, number = {60}, pages = {9355--9358}, publisher = {Royal Society of Chemistry}, title = {{Crystal structure of a complex between β-glucopyranose and a macrocyclic receptor with dendritic multicharged water solubilizing chains}}, doi = {10.1039/c6cc04466b}, volume = {52}, year = {2016}, } @article{13395, abstract = {Metallic nanoparticles co-functionalised with monolayers of UV- and CO2-sensitive ligands were prepared and shown to respond to these two types of stimuli reversibly and in an orthogonal fashion. The composition of the coating could be tailored to yield nanoparticles capable of aggregating exclusively when both UV and CO2 were applied at the same time, analogously to the behaviour of an AND logic gate.}, author = {Lee, Ji-Woong and Klajn, Rafal}, issn = {1364-548X}, journal = {Chemical Communications}, keywords = {Materials Chemistry, Metals and Alloys, Surfaces, Coatings and Films, General Chemistry, Ceramics and Composites, Electronic, Optical and Magnetic Materials, Catalysis}, number = {11}, pages = {2036--2039}, publisher = {Royal Society of Chemistry}, title = {{Dual-responsive nanoparticles that aggregate under the simultaneous action of light and CO2}}, doi = {10.1039/c4cc08541h}, volume = {51}, year = {2015}, }