---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20670'
abstract:
- lang: eng
text: 'β-Barrel nanopores are involved in crucial biological processes, from ATP
export in mitochondria to bacterial resistance, and represent a promising platform
for emerging sequencing technologies. However, in contrast to ion channels, the
understanding of the fundamental principles governing ion transport through these
nanopores remains largely unexplored. Here we integrate experimental, numerical
and theoretical approaches to elucidate ion transport mechanisms in β-barrel nanopores.
We identify and characterize two distinct nonlinear phenomena: open-pore rectification
and gating. Through extensive mutation analysis of aerolysin nanopores, we demonstrate
that open-pore rectification is caused by ionic accumulation driven by the distribution
of lumen charges. In addition, we provide converging evidence suggesting that
gating is controlled by electric fields dissociating counterions from lumen charges,
promoting local structural deformations. Our findings establish a rigorous framework
for characterizing and understanding ion transport processes in protein-based
nanopores, enabling the design of adaptable nanofluidic biotechnologies. We illustrate
this by optimizing an aerolysin mutant for computing applications.'
acknowledgement: We are grateful to M. Mayer and G. van der Goot for their insightful
discussions and thoughtful feedback. We acknowledge funding from the European Research
Council (grants 101020445—2D-LIQUID N.R. and A.R., MSCA number 101034413 P.R.),
the Swiss National Science Foundation (grants 205321_192371 and 200021L_212128 to
M.D.P., TMPFP2-217134 to T.E., and IZSEZ0_183779 to J.H.G. and A.R.) and the Swiss
National Supercomputing Centre (CSCS) for access to the HPC resources used to run
MD simulations. We thank the staff members of the Dubochet Center for Imaging in
Lausanne, in particular E. Uchikawa and S. Nazarov, for their assistance with cryo-EM
sample preparation and data collection. We thank A. Antanasijevic and Y. Duhoo from
EPFL Protein Production and Structure Core Facility for their support in cryo-EM
data processing.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Simon
full_name: Mayer, Simon
last_name: Mayer
- first_name: Marianna Fanouria
full_name: Mitsioni, Marianna Fanouria
last_name: Mitsioni
- first_name: Paul
full_name: Robin, Paul
id: 48c58128-57b0-11ee-9095-dc28fd97fc1d
last_name: Robin
orcid: 0000-0002-5728-9189
- first_name: Lukas
full_name: Van Den Heuvel, Lukas
last_name: Van Den Heuvel
- first_name: Nathan
full_name: Ronceray, Nathan
last_name: Ronceray
- first_name: Maria Jose
full_name: Marcaida, Maria Jose
last_name: Marcaida
- first_name: Luciano A.
full_name: Abriata, Luciano A.
last_name: Abriata
- first_name: Lucien F.
full_name: Krapp, Lucien F.
last_name: Krapp
- first_name: Jana S.
full_name: Anton, Jana S.
last_name: Anton
- first_name: Sarah
full_name: Soussou, Sarah
last_name: Soussou
- first_name: Justin
full_name: Jeanneret-Grosjean, Justin
last_name: Jeanneret-Grosjean
- first_name: Alessandro
full_name: Fulciniti, Alessandro
last_name: Fulciniti
- first_name: Alexia
full_name: Möller, Alexia
last_name: Möller
- first_name: Sarah
full_name: Vacle, Sarah
last_name: Vacle
- first_name: Lely
full_name: Feletti, Lely
last_name: Feletti
- first_name: Henry
full_name: Brinkerhoff, Henry
last_name: Brinkerhoff
- first_name: Andrew H.
full_name: Laszlo, Andrew H.
last_name: Laszlo
- first_name: Jens H.
full_name: Gundlach, Jens H.
last_name: Gundlach
- first_name: Theo
full_name: Emmerich, Theo
last_name: Emmerich
- first_name: Matteo
full_name: Dal Peraro, Matteo
last_name: Dal Peraro
- first_name: Aleksandra
full_name: Radenovic, Aleksandra
last_name: Radenovic
citation:
ama: Mayer S, Mitsioni MF, Robin P, et al. Lumen charge governs gated ion transport
in β-barrel nanopores. Nature Nanotechnology. 2026;21:116-124. doi:10.1038/s41565-025-02052-6
apa: Mayer, S., Mitsioni, M. F., Robin, P., Van Den Heuvel, L., Ronceray, N., Marcaida,
M. J., … Radenovic, A. (2026). Lumen charge governs gated ion transport in β-barrel
nanopores. Nature Nanotechnology. Springer Nature. https://doi.org/10.1038/s41565-025-02052-6
chicago: Mayer, Simon, Marianna Fanouria Mitsioni, Paul Robin, Lukas Van Den Heuvel,
Nathan Ronceray, Maria Jose Marcaida, Luciano A. Abriata, et al. “Lumen Charge
Governs Gated Ion Transport in β-Barrel Nanopores.” Nature Nanotechnology.
Springer Nature, 2026. https://doi.org/10.1038/s41565-025-02052-6.
ieee: S. Mayer et al., “Lumen charge governs gated ion transport in β-barrel
nanopores,” Nature Nanotechnology, vol. 21. Springer Nature, pp. 116–124,
2026.
ista: Mayer S, Mitsioni MF, Robin P, Van Den Heuvel L, Ronceray N, Marcaida MJ,
Abriata LA, Krapp LF, Anton JS, Soussou S, Jeanneret-Grosjean J, Fulciniti A,
Möller A, Vacle S, Feletti L, Brinkerhoff H, Laszlo AH, Gundlach JH, Emmerich
T, Dal Peraro M, Radenovic A. 2026. Lumen charge governs gated ion transport in
β-barrel nanopores. Nature Nanotechnology. 21, 116–124.
mla: Mayer, Simon, et al. “Lumen Charge Governs Gated Ion Transport in β-Barrel
Nanopores.” Nature Nanotechnology, vol. 21, Springer Nature, 2026, pp.
116–24, doi:10.1038/s41565-025-02052-6.
short: S. Mayer, M.F. Mitsioni, P. Robin, L. Van Den Heuvel, N. Ronceray, M.J. Marcaida,
L.A. Abriata, L.F. Krapp, J.S. Anton, S. Soussou, J. Jeanneret-Grosjean, A. Fulciniti,
A. Möller, S. Vacle, L. Feletti, H. Brinkerhoff, A.H. Laszlo, J.H. Gundlach, T.
Emmerich, M. Dal Peraro, A. Radenovic, Nature Nanotechnology 21 (2026) 116–124.
das_tickbox: '1'
dataavailabilitystatement: All data that support the findings of this study are available
within the article and its Supplementary Information. Source data are available
via Zenodo at https://doi.org/10.5281/zenodo.17200775 (ref. 64). Cryo-EM data for
aerolysin can be accessed through the EMDB with the code EMD-51664 for E254A–E258A
and EMD-52853 for post-prepore and quasipore. All data processing codes, simulation
and modelling codes are available at https://github.com/lukasvandenheuvel/Biomemristors.
date_created: 2025-11-23T23:01:40Z
date_published: 2026-01-01T00:00:00Z
date_updated: 2026-07-27T08:24:20Z
day: '01'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1038/s41565-025-02052-6
external_id:
isi:
- '001611698900001'
pmid:
- '41219410'
file:
- access_level: open_access
checksum: ff9a5eafe60af1d97da545453bd53eca
content_type: application/pdf
creator: dernst
date_created: 2026-07-27T08:22:57Z
date_updated: 2026-07-27T08:22:57Z
file_id: '22412'
file_name: 2026_NatureNanotech_Mayer.pdf
file_size: 10091503
relation: main_file
success: 1
file_date_updated: 2026-07-27T08:22:57Z
has_accepted_license: '1'
intvolume: ' 21'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 116-124
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://github.com/lukasvandenheuvel/Biomemristors
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Lumen charge governs gated ion transport in β-barrel nanopores
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '17480'
abstract:
- lang: eng
text: One of the most promising approaches towards large-scale quantum computation
uses devices based on many Josephson junctions. Yet, even today, open questions
regarding the single junction remain unsolved, such as the detailed understanding
of the quantum phase transitions, the coupling of the Josephson junction to the
environment or how to improve the coherence of a superconducting qubit. Here we
design and build an engineered on-chip reservoir connected to a Josephson junction
that acts as an efficient bolometer for detecting the Josephson radiation under
non-equilibrium, that is, biased conditions. The bolometer converts the a.c. Josephson
current at microwave frequencies up to about 100 GHz into a temperature rise measured
by d.c. thermometry. A circuit model based on realistic parameter values captures
both the current–voltage characteristics and the measured power quantitatively.
The present experiment demonstrates an efficient, wide-band, thermal detection
scheme of microwave photons and provides a sensitive detector of Josephson dynamics
beyond the standard conductance measurements.
acknowledgement: We thank M. Möttönen, D. Subero, V. Vadimov, A. Alizadeh, C. Strunk,
N. Roch, S. Kafanov, S. Kubatkin, A. Kerman and J. Peltonen for scientific discussions
and Z.-Y. Chen for technical assistance. B.K. and J.P.P. acknowledge funding from
the Research Council of Finland Centre of Excellence programme grant 336810 and
grant 349601 (THEPOW), G.O.S. and A.L.Y. financial support from the Spanish Ministry
of Science through grant TED2021-130292B-C43 funded by MCIN/AEI/10.13039/501100011033,
‘ERDF A way of making Europe’ and the EU through FET-Open project AndQC, A.P.H.
support from the NOMIS Foundation, and C.M.M. support from the Danish National Research
Foundation and a research grant (Project 43951) from VILLUM FONDEN. We thank the
facilities and technical support of Otaniemi Research Infrastructure for Micro and
Nanotechnologies (OtaNano). The funders had no role in study design, data collection
and analysis, decision to publish or preparation of the paper.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Bayan
full_name: Karimi, Bayan
last_name: Karimi
- first_name: Gorm Ole
full_name: Steffensen, Gorm Ole
last_name: Steffensen
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: Charles M.
full_name: Marcus, Charles M.
last_name: Marcus
- first_name: Alfredo
full_name: Levy Yeyati, Alfredo
last_name: Levy Yeyati
- first_name: Jukka P.
full_name: Pekola, Jukka P.
last_name: Pekola
citation:
ama: Karimi B, Steffensen GO, Higginbotham AP, Marcus CM, Levy Yeyati A, Pekola
JP. Bolometric detection of Josephson radiation. Nature Nanotechnology.
2024;19:1613-1618. doi:10.1038/s41565-024-01770-7
apa: Karimi, B., Steffensen, G. O., Higginbotham, A. P., Marcus, C. M., Levy Yeyati,
A., & Pekola, J. P. (2024). Bolometric detection of Josephson radiation. Nature
Nanotechnology. Springer Nature. https://doi.org/10.1038/s41565-024-01770-7
chicago: Karimi, Bayan, Gorm Ole Steffensen, Andrew P Higginbotham, Charles M. Marcus,
Alfredo Levy Yeyati, and Jukka P. Pekola. “Bolometric Detection of Josephson Radiation.”
Nature Nanotechnology. Springer Nature, 2024. https://doi.org/10.1038/s41565-024-01770-7.
ieee: B. Karimi, G. O. Steffensen, A. P. Higginbotham, C. M. Marcus, A. Levy Yeyati,
and J. P. Pekola, “Bolometric detection of Josephson radiation,” Nature Nanotechnology,
vol. 19. Springer Nature, pp. 1613–1618, 2024.
ista: Karimi B, Steffensen GO, Higginbotham AP, Marcus CM, Levy Yeyati A, Pekola
JP. 2024. Bolometric detection of Josephson radiation. Nature Nanotechnology.
19, 1613–1618.
mla: Karimi, Bayan, et al. “Bolometric Detection of Josephson Radiation.” Nature
Nanotechnology, vol. 19, Springer Nature, 2024, pp. 1613–18, doi:10.1038/s41565-024-01770-7.
short: B. Karimi, G.O. Steffensen, A.P. Higginbotham, C.M. Marcus, A. Levy Yeyati,
J.P. Pekola, Nature Nanotechnology 19 (2024) 1613–1618.
date_created: 2024-09-01T22:01:09Z
date_published: 2024-11-01T00:00:00Z
date_updated: 2026-06-03T07:16:01Z
day: '01'
ddc:
- '530'
department:
- _id: AnHi
doi: 10.1038/s41565-024-01770-7
external_id:
arxiv:
- '2402.09314'
isi:
- '001296522000002'
file:
- access_level: open_access
checksum: 8b067ef217ddef63c539ecdfe705ab95
content_type: application/pdf
creator: dernst
date_created: 2025-01-09T13:51:12Z
date_updated: 2025-01-09T13:51:12Z
file_id: '18818'
file_name: 2024_NatureNanotechnology_Karimi.pdf
file_size: 3047567
relation: main_file
success: 1
file_date_updated: 2025-01-09T13:51:12Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 1613-1618
project:
- _id: eb9b30ac-77a9-11ec-83b8-871f581d53d2
name: Protected states of quantum matter
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bolometric detection of Josephson radiation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 19
year: '2024'
...
---
_id: '13352'
abstract:
- lang: eng
text: Optoelectronic effects differentiating absorption of right and left circularly
polarized photons in thin films of chiral materials are typically prohibitively
small for their direct photocurrent observation. Chiral metasurfaces increase
the electronic sensitivity to circular polarization, but their out-of-plane architecture
entails manufacturing and performance trade-offs. Here, we show that nanoporous
thin films of chiral nanoparticles enable high sensitivity to circular polarization
due to light-induced polarization-dependent ion accumulation at nanoparticle interfaces.
Self-assembled multilayers of gold nanoparticles modified with L-phenylalanine
generate a photocurrent under right-handed circularly polarized light as high
as 2.41 times higher than under left-handed circularly polarized light. The strong
plasmonic coupling between the multiple nanoparticles producing planar chiroplasmonic
modes facilitates the ejection of electrons, whose entrapment at the membrane–electrolyte
interface is promoted by a thick layer of enantiopure phenylalanine. Demonstrated
detection of light ellipticity with equal sensitivity at all incident angles mimics
phenomenological aspects of polarization vision in marine animals. The simplicity
of self-assembly and sensitivity of polarization detection found in optoionic
membranes opens the door to a family of miniaturized fluidic devices for chiral
photonics.
article_processing_charge: No
article_type: original
author:
- first_name: Jiarong
full_name: Cai, Jiarong
last_name: Cai
- first_name: Wei
full_name: Zhang, Wei
last_name: Zhang
- first_name: Liguang
full_name: Xu, Liguang
last_name: Xu
- first_name: Changlong
full_name: Hao, Changlong
last_name: Hao
- first_name: Wei
full_name: Ma, Wei
last_name: Ma
- first_name: Maozhong
full_name: Sun, Maozhong
last_name: Sun
- first_name: Xiaoling
full_name: Wu, Xiaoling
last_name: Wu
- first_name: Xian
full_name: Qin, Xian
last_name: Qin
- first_name: Felippe Mariano
full_name: Colombari, Felippe Mariano
last_name: Colombari
- first_name: André Farias
full_name: de Moura, André Farias
last_name: de Moura
- first_name: Jiahui
full_name: Xu, Jiahui
last_name: Xu
- first_name: Mariana Cristina
full_name: Silva, Mariana Cristina
last_name: Silva
- first_name: Evaldo Batista
full_name: Carneiro-Neto, Evaldo Batista
last_name: Carneiro-Neto
- first_name: Weverson Rodrigues
full_name: Gomes, Weverson Rodrigues
last_name: Gomes
- first_name: Renaud A. L.
full_name: Vallée, Renaud A. L.
last_name: Vallée
- first_name: Ernesto Chaves
full_name: Pereira, Ernesto Chaves
last_name: Pereira
- first_name: Xiaogang
full_name: Liu, Xiaogang
last_name: Liu
- first_name: Chuanlai
full_name: Xu, Chuanlai
last_name: Xu
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Nicholas A.
full_name: Kotov, Nicholas A.
last_name: Kotov
- first_name: Hua
full_name: Kuang, Hua
last_name: Kuang
citation:
ama: Cai J, Zhang W, Xu L, et al. Polarization-sensitive optoionic membranes from
chiral plasmonic nanoparticles. Nature Nanotechnology. 2022;17(4):408-416.
doi:10.1038/s41565-022-01079-3
apa: Cai, J., Zhang, W., Xu, L., Hao, C., Ma, W., Sun, M., … Kuang, H. (2022). Polarization-sensitive
optoionic membranes from chiral plasmonic nanoparticles. Nature Nanotechnology.
Springer Nature. https://doi.org/10.1038/s41565-022-01079-3
chicago: Cai, Jiarong, Wei Zhang, Liguang Xu, Changlong Hao, Wei Ma, Maozhong Sun,
Xiaoling Wu, et al. “Polarization-Sensitive Optoionic Membranes from Chiral Plasmonic
Nanoparticles.” Nature Nanotechnology. Springer Nature, 2022. https://doi.org/10.1038/s41565-022-01079-3.
ieee: J. Cai et al., “Polarization-sensitive optoionic membranes from chiral
plasmonic nanoparticles,” Nature Nanotechnology, vol. 17, no. 4. Springer
Nature, pp. 408–416, 2022.
ista: Cai J, Zhang W, Xu L, Hao C, Ma W, Sun M, Wu X, Qin X, Colombari FM, de Moura
AF, Xu J, Silva MC, Carneiro-Neto EB, Gomes WR, Vallée RAL, Pereira EC, Liu X,
Xu C, Klajn R, Kotov NA, Kuang H. 2022. Polarization-sensitive optoionic membranes
from chiral plasmonic nanoparticles. Nature Nanotechnology. 17(4), 408–416.
mla: Cai, Jiarong, et al. “Polarization-Sensitive Optoionic Membranes from Chiral
Plasmonic Nanoparticles.” Nature Nanotechnology, vol. 17, no. 4, Springer
Nature, 2022, pp. 408–16, doi:10.1038/s41565-022-01079-3.
short: J. Cai, W. Zhang, L. Xu, C. Hao, W. Ma, M. Sun, X. Wu, X. Qin, F.M. Colombari,
A.F. de Moura, J. Xu, M.C. Silva, E.B. Carneiro-Neto, W.R. Gomes, R.A.L. Vallée,
E.C. Pereira, X. Liu, C. Xu, R. Klajn, N.A. Kotov, H. Kuang, Nature Nanotechnology
17 (2022) 408–416.
date_created: 2023-08-01T09:32:40Z
date_published: 2022-03-14T00:00:00Z
date_updated: 2024-10-14T12:10:13Z
day: '14'
doi: 10.1038/s41565-022-01079-3
extern: '1'
external_id:
pmid:
- '35288671'
intvolume: ' 17'
issue: '4'
keyword:
- Electrical and Electronic Engineering
- Condensed Matter Physics
- General Materials Science
- Biomedical Engineering
- Atomic and Molecular Physics
- and Optics
- Bioengineering
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://hal.science/hal-03623036/
month: '03'
oa: 1
oa_version: Published Version
page: 408-416
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polarization-sensitive optoionic membranes from chiral plasmonic nanoparticles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2022'
...
---
OA_type: closed access
_id: '17900'
abstract:
- lang: eng
text: To rival the performance of modern integrated circuits, single-molecule devices
must be designed to exhibit extremely nonlinear current–voltage (I–V) characteristics1,2,3,4.
A common approach is to design molecular backbones where destructive quantum interference
(QI) between the highest occupied molecular orbital (HOMO) and the lowest unoccupied
molecular orbital (LUMO) produces a nonlinear energy-dependent tunnelling probability
near the electrode Fermi energy (EF)5,6,7,8. However, tuning such systems is not
straightforward, as aligning the frontier orbitals to EF is hard to control9.
Here, we instead create a molecular system where constructive QI between the HOMO
and LUMO is suppressed and destructive QI between the HOMO and strongly coupled
occupied orbitals of opposite phase is enhanced. We use a series of fluorene oligomers
containing a central benzothiadiazole10 unit to demonstrate that this strategy
can be used to create highly nonlinear single-molecule circuits. Notably, we are
able to reproducibly modulate the conductance of a 6-nm molecule by a factor of
more than 10^4.
article_processing_charge: No
author:
- first_name: Julia E.
full_name: Greenwald, Julia E.
last_name: Greenwald
- first_name: Joseph
full_name: Cameron, Joseph
last_name: Cameron
- first_name: Neil J.
full_name: Findlay, Neil J.
last_name: Findlay
- first_name: Tianren
full_name: Fu, Tianren
last_name: Fu
- first_name: Suman
full_name: Gunasekaran, Suman
last_name: Gunasekaran
- first_name: Peter J.
full_name: Skabara, Peter J.
last_name: Skabara
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
citation:
ama: Greenwald JE, Cameron J, Findlay NJ, et al. Highly nonlinear transport across
single-molecule junctions via destructive quantum interference. Nature Nanotechnology.
2021;16(3):313-317. doi:10.1038/s41565-020-00807-x
apa: Greenwald, J. E., Cameron, J., Findlay, N. J., Fu, T., Gunasekaran, S., Skabara,
P. J., & Venkataraman, L. (2021). Highly nonlinear transport across single-molecule
junctions via destructive quantum interference. Nature Nanotechnology.
Springer Nature. https://doi.org/10.1038/s41565-020-00807-x
chicago: Greenwald, Julia E., Joseph Cameron, Neil J. Findlay, Tianren Fu, Suman
Gunasekaran, Peter J. Skabara, and Latha Venkataraman. “Highly Nonlinear Transport
across Single-Molecule Junctions via Destructive Quantum Interference.” Nature
Nanotechnology. Springer Nature, 2021. https://doi.org/10.1038/s41565-020-00807-x.
ieee: J. E. Greenwald et al., “Highly nonlinear transport across single-molecule
junctions via destructive quantum interference,” Nature Nanotechnology,
vol. 16, no. 3. Springer Nature, pp. 313–317, 2021.
ista: Greenwald JE, Cameron J, Findlay NJ, Fu T, Gunasekaran S, Skabara PJ, Venkataraman
L. 2021. Highly nonlinear transport across single-molecule junctions via destructive
quantum interference. Nature Nanotechnology. 16(3), 313–317.
mla: Greenwald, Julia E., et al. “Highly Nonlinear Transport across Single-Molecule
Junctions via Destructive Quantum Interference.” Nature Nanotechnology,
vol. 16, no. 3, Springer Nature, 2021, pp. 313–17, doi:10.1038/s41565-020-00807-x.
short: J.E. Greenwald, J. Cameron, N.J. Findlay, T. Fu, S. Gunasekaran, P.J. Skabara,
L. Venkataraman, Nature Nanotechnology 16 (2021) 313–317.
date_created: 2024-09-09T06:43:51Z
date_published: 2021-03-01T00:00:00Z
date_updated: 2024-12-10T10:20:32Z
day: '01'
doi: 10.1038/s41565-020-00807-x
extern: '1'
external_id:
pmid:
- '33288949'
intvolume: ' 16'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 313-317
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Highly nonlinear transport across single-molecule junctions via destructive
quantum interference
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2021'
...
---
_id: '13367'
abstract:
- lang: eng
text: Confining molecules can fundamentally change their chemical and physical properties.
Confinement effects are considered instrumental at various stages of the origins
of life, and life continues to rely on layers of compartmentalization to maintain
an out-of-equilibrium state and efficiently synthesize complex biomolecules under
mild conditions. As interest in synthetic confined systems grows, we are realizing
that the principles governing reactivity under confinement are the same in abiological
systems as they are in nature. In this Review, we categorize the ways in which
nanoconfinement effects impact chemical reactivity in synthetic systems. Under
nanoconfinement, chemical properties can be modulated to increase reaction rates,
enhance selectivity and stabilize reactive species. Confinement effects also lead
to changes in physical properties. The fluorescence of light emitters, the colours
of dyes and electronic communication between electroactive species can all be
tuned under confinement. Within each of these categories, we elucidate design
principles and strategies that are widely applicable across a range of confined
systems, specifically highlighting examples of different nanocompartments that
influence reactivity in similar ways.
article_processing_charge: No
article_type: original
author:
- first_name: Angela B.
full_name: Grommet, Angela B.
last_name: Grommet
- first_name: Moran
full_name: Feller, Moran
last_name: Feller
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Grommet AB, Feller M, Klajn R. Chemical reactivity under nanoconfinement. Nature
Nanotechnology. 2020;15:256-271. doi:10.1038/s41565-020-0652-2
apa: Grommet, A. B., Feller, M., & Klajn, R. (2020). Chemical reactivity under
nanoconfinement. Nature Nanotechnology. Springer Nature. https://doi.org/10.1038/s41565-020-0652-2
chicago: Grommet, Angela B., Moran Feller, and Rafal Klajn. “Chemical Reactivity
under Nanoconfinement.” Nature Nanotechnology. Springer Nature, 2020. https://doi.org/10.1038/s41565-020-0652-2.
ieee: A. B. Grommet, M. Feller, and R. Klajn, “Chemical reactivity under nanoconfinement,”
Nature Nanotechnology, vol. 15. Springer Nature, pp. 256–271, 2020.
ista: Grommet AB, Feller M, Klajn R. 2020. Chemical reactivity under nanoconfinement.
Nature Nanotechnology. 15, 256–271.
mla: Grommet, Angela B., et al. “Chemical Reactivity under Nanoconfinement.” Nature
Nanotechnology, vol. 15, Springer Nature, 2020, pp. 256–71, doi:10.1038/s41565-020-0652-2.
short: A.B. Grommet, M. Feller, R. Klajn, Nature Nanotechnology 15 (2020) 256–271.
date_created: 2023-08-01T09:37:39Z
date_published: 2020-04-17T00:00:00Z
date_updated: 2024-10-14T12:13:35Z
day: '17'
doi: 10.1038/s41565-020-0652-2
extern: '1'
external_id:
pmid:
- '32303705'
intvolume: ' 15'
keyword:
- Electrical and Electronic Engineering
- Condensed Matter Physics
- General Materials Science
- Biomedical Engineering
- Atomic and Molecular Physics
- and Optics
- Bioengineering
language:
- iso: eng
month: '04'
oa_version: None
page: 256-271
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chemical reactivity under nanoconfinement
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2020'
...
---
_id: '6053'
abstract:
- lang: eng
text: Recent technical developments in the fields of quantum electromechanics and
optomechanics have spawned nanoscale mechanical transducers with the sensitivity
to measure mechanical displacements at the femtometre scale and the ability to
convert electromagnetic signals at the single photon level. A key challenge in
this field is obtaining strong coupling between motion and electromagnetic fields
without adding additional decoherence. Here we present an electromechanical transducer
that integrates a high-frequency (0.42 GHz) hypersonic phononic crystal with a
superconducting microwave circuit. The use of a phononic bandgap crystal enables
quantum-level transduction of hypersonic mechanical motion and concurrently eliminates
decoherence caused by acoustic radiation. Devices with hypersonic mechanical frequencies
provide a natural pathway for integration with Josephson junction quantum circuits,
a leading quantum computing technology, and nanophotonic systems capable of optical
networking and distributing quantum information.
article_processing_charge: No
article_type: original
author:
- first_name: Mahmoud
full_name: Kalaee, Mahmoud
last_name: Kalaee
- first_name: Mohammad
full_name: Mirhosseini, Mohammad
last_name: Mirhosseini
- first_name: Paul B.
full_name: Dieterle, Paul B.
last_name: Dieterle
- first_name: Matilda
full_name: Peruzzo, Matilda
id: 3F920B30-F248-11E8-B48F-1D18A9856A87
last_name: Peruzzo
orcid: 0000-0002-3415-4628
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Oskar
full_name: Painter, Oskar
last_name: Painter
citation:
ama: Kalaee M, Mirhosseini M, Dieterle PB, Peruzzo M, Fink JM, Painter O. Quantum
electromechanics of a hypersonic crystal. Nature Nanotechnology. 2019;14(4):334–339.
doi:10.1038/s41565-019-0377-2
apa: Kalaee, M., Mirhosseini, M., Dieterle, P. B., Peruzzo, M., Fink, J. M., &
Painter, O. (2019). Quantum electromechanics of a hypersonic crystal. Nature
Nanotechnology. Springer Nature. https://doi.org/10.1038/s41565-019-0377-2
chicago: Kalaee, Mahmoud, Mohammad Mirhosseini, Paul B. Dieterle, Matilda Peruzzo,
Johannes M Fink, and Oskar Painter. “Quantum Electromechanics of a Hypersonic
Crystal.” Nature Nanotechnology. Springer Nature, 2019. https://doi.org/10.1038/s41565-019-0377-2.
ieee: M. Kalaee, M. Mirhosseini, P. B. Dieterle, M. Peruzzo, J. M. Fink, and O.
Painter, “Quantum electromechanics of a hypersonic crystal,” Nature Nanotechnology,
vol. 14, no. 4. Springer Nature, pp. 334–339, 2019.
ista: Kalaee M, Mirhosseini M, Dieterle PB, Peruzzo M, Fink JM, Painter O. 2019.
Quantum electromechanics of a hypersonic crystal. Nature Nanotechnology. 14(4),
334–339.
mla: Kalaee, Mahmoud, et al. “Quantum Electromechanics of a Hypersonic Crystal.”
Nature Nanotechnology, vol. 14, no. 4, Springer Nature, 2019, pp. 334–339,
doi:10.1038/s41565-019-0377-2.
short: M. Kalaee, M. Mirhosseini, P.B. Dieterle, M. Peruzzo, J.M. Fink, O. Painter,
Nature Nanotechnology 14 (2019) 334–339.
date_created: 2019-02-24T22:59:21Z
date_published: 2019-04-01T00:00:00Z
date_updated: 2023-08-24T14:48:08Z
day: '01'
department:
- _id: JoFi
doi: 10.1038/s41565-019-0377-2
external_id:
isi:
- '000463195700014'
intvolume: ' 14'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://authors.library.caltech.edu/92123/
month: '04'
oa: 1
oa_version: Submitted Version
page: 334–339
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantum electromechanics of a hypersonic crystal
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2019'
...
---
OA_type: closed access
_id: '17937'
abstract:
- lang: eng
text: Fabricating nanoscopic devices capable of manipulating and processing single
units of charge is an essential step towards creating functional devices where
quantum effects dominate transport characteristics. The archetypal single-electron
transistor comprises a small conducting or semiconducting island separated from
two metallic reservoirs by insulating barriers1,2,3,4,5. By enabling the transfer
of a well-defined number of charge carriers between the island and the reservoirs,
such a device may enable discrete single-electron operations6,7,8,9. Here, we
describe a single-molecule junction comprising a redox-active, atomically precise
cobalt chalcogenide cluster wired between two nanoscopic electrodes10,11. We observe
current blockade at room temperature in thousands of single-cluster junctions.
Below a threshold voltage, charge transfer across the junction is suppressed.
The device is turned on when the temporary occupation of the core states by a
transiting carrier is energetically enabled, resulting in a sequential tunnelling
process and an increase in current by a factor of ∼600. We perform in situ and
ex situ cyclic voltammetry as well as density functional theory calculations to
unveil a two-step process mediated by an orbital localized on the core of the
cluster in which charge carriers reside before tunnelling to the collector reservoir.
As the bias window of the junction is opened wide enough to include one of the
cluster frontier orbitals, the current blockade is lifted and charge carriers
can tunnel sequentially across the junction.
article_processing_charge: No
article_type: original
author:
- first_name: Giacomo
full_name: Lovat, Giacomo
last_name: Lovat
- first_name: Bonnie
full_name: Choi, Bonnie
last_name: Choi
- first_name: Daniel W.
full_name: Paley, Daniel W.
last_name: Paley
- first_name: Michael L.
full_name: Steigerwald, Michael L.
last_name: Steigerwald
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
- first_name: Xavier
full_name: Roy, Xavier
last_name: Roy
citation:
ama: Lovat G, Choi B, Paley DW, Steigerwald ML, Venkataraman L, Roy X. Room-temperature
current blockade in atomically defined single-cluster junctions. Nature Nanotechnology.
2017;12:1050-1054. doi:10.1038/nnano.2017.156
apa: Lovat, G., Choi, B., Paley, D. W., Steigerwald, M. L., Venkataraman, L., &
Roy, X. (2017). Room-temperature current blockade in atomically defined single-cluster
junctions. Nature Nanotechnology. Springer Nature. https://doi.org/10.1038/nnano.2017.156
chicago: Lovat, Giacomo, Bonnie Choi, Daniel W. Paley, Michael L. Steigerwald, Latha
Venkataraman, and Xavier Roy. “Room-Temperature Current Blockade in Atomically
Defined Single-Cluster Junctions.” Nature Nanotechnology. Springer Nature,
2017. https://doi.org/10.1038/nnano.2017.156.
ieee: G. Lovat, B. Choi, D. W. Paley, M. L. Steigerwald, L. Venkataraman, and X.
Roy, “Room-temperature current blockade in atomically defined single-cluster junctions,”
Nature Nanotechnology, vol. 12. Springer Nature, pp. 1050–1054, 2017.
ista: Lovat G, Choi B, Paley DW, Steigerwald ML, Venkataraman L, Roy X. 2017. Room-temperature
current blockade in atomically defined single-cluster junctions. Nature Nanotechnology.
12, 1050–1054.
mla: Lovat, Giacomo, et al. “Room-Temperature Current Blockade in Atomically Defined
Single-Cluster Junctions.” Nature Nanotechnology, vol. 12, Springer Nature,
2017, pp. 1050–54, doi:10.1038/nnano.2017.156.
short: G. Lovat, B. Choi, D.W. Paley, M.L. Steigerwald, L. Venkataraman, X. Roy,
Nature Nanotechnology 12 (2017) 1050–1054.
date_created: 2024-09-09T08:46:15Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2024-12-17T10:09:35Z
day: '01'
doi: 10.1038/nnano.2017.156
extern: '1'
external_id:
pmid:
- '28805817'
intvolume: ' 12'
language:
- iso: eng
month: '11'
oa_version: None
page: 1050-1054
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Room-temperature current blockade in atomically defined single-cluster junctions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2017'
...
---
_id: '13392'
abstract:
- lang: eng
text: The chemical behaviour of molecules can be significantly modified by confinement
to volumes comparable to the dimensions of the molecules. Although such confined
spaces can be found in various nanostructured materials, such as zeolites, nanoporous
organic frameworks and colloidal nanocrystal assemblies, the slow diffusion of
molecules in and out of these materials has greatly hampered studying the effect
of confinement on their physicochemical properties. Here, we show that this diffusion
limitation can be overcome by reversibly creating and destroying confined environments
by means of ultraviolet and visible light irradiation. We use colloidal nanocrystals
functionalized with light-responsive ligands that readily self-assemble and trap
various molecules from the surrounding bulk solution. Once trapped, these molecules
can undergo chemical reactions with increased rates and with stereoselectivities
significantly different from those in bulk solution. Illumination with visible
light disassembles these nanoflasks, releasing the product in solution and thereby
establishes a catalytic cycle. These dynamic nanoflasks can be useful for studying
chemical reactivities in confined environments and for synthesizing molecules
that are otherwise hard to achieve in bulk solution.
article_processing_charge: No
article_type: original
author:
- first_name: Hui
full_name: Zhao, Hui
last_name: Zhao
- first_name: Soumyo
full_name: Sen, Soumyo
last_name: Sen
- first_name: T.
full_name: Udayabhaskararao, T.
last_name: Udayabhaskararao
- first_name: Michał
full_name: Sawczyk, Michał
last_name: Sawczyk
- first_name: Kristina
full_name: Kučanda, Kristina
last_name: Kučanda
- first_name: Debasish
full_name: Manna, Debasish
last_name: Manna
- first_name: Pintu K.
full_name: Kundu, Pintu K.
last_name: Kundu
- first_name: Ji-Woong
full_name: Lee, Ji-Woong
last_name: Lee
- first_name: Petr
full_name: Král, Petr
last_name: Král
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Zhao H, Sen S, Udayabhaskararao T, et al. Reversible trapping and reaction
acceleration within dynamically self-assembling nanoflasks. Nature Nanotechnology.
2015;11:82-88. doi:10.1038/nnano.2015.256
apa: Zhao, H., Sen, S., Udayabhaskararao, T., Sawczyk, M., Kučanda, K., Manna, D.,
… Klajn, R. (2015). Reversible trapping and reaction acceleration within dynamically
self-assembling nanoflasks. Nature Nanotechnology. Springer Nature. https://doi.org/10.1038/nnano.2015.256
chicago: Zhao, Hui, Soumyo Sen, T. Udayabhaskararao, Michał Sawczyk, Kristina Kučanda,
Debasish Manna, Pintu K. Kundu, Ji-Woong Lee, Petr Král, and Rafal Klajn. “Reversible
Trapping and Reaction Acceleration within Dynamically Self-Assembling Nanoflasks.”
Nature Nanotechnology. Springer Nature, 2015. https://doi.org/10.1038/nnano.2015.256.
ieee: H. Zhao et al., “Reversible trapping and reaction acceleration within
dynamically self-assembling nanoflasks,” Nature Nanotechnology, vol. 11.
Springer Nature, pp. 82–88, 2015.
ista: Zhao H, Sen S, Udayabhaskararao T, Sawczyk M, Kučanda K, Manna D, Kundu PK,
Lee J-W, Král P, Klajn R. 2015. Reversible trapping and reaction acceleration
within dynamically self-assembling nanoflasks. Nature Nanotechnology. 11, 82–88.
mla: Zhao, Hui, et al. “Reversible Trapping and Reaction Acceleration within Dynamically
Self-Assembling Nanoflasks.” Nature Nanotechnology, vol. 11, Springer Nature,
2015, pp. 82–88, doi:10.1038/nnano.2015.256.
short: H. Zhao, S. Sen, T. Udayabhaskararao, M. Sawczyk, K. Kučanda, D. Manna, P.K.
Kundu, J.-W. Lee, P. Král, R. Klajn, Nature Nanotechnology 11 (2015) 82–88.
date_created: 2023-08-01T09:44:04Z
date_published: 2015-11-23T00:00:00Z
date_updated: 2024-10-14T12:17:26Z
day: '23'
doi: 10.1038/nnano.2015.256
extern: '1'
external_id:
pmid:
- '26595335'
intvolume: ' 11'
keyword:
- Electrical and Electronic Engineering
- Condensed Matter Physics
- General Materials Science
- Biomedical Engineering
- Atomic and Molecular Physics
- and Optics
- Bioengineering
language:
- iso: eng
month: '11'
oa_version: None
page: 82-88
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Reversible trapping and reaction acceleration within dynamically self-assembling
nanoflasks
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2015'
...
---
OA_type: closed access
_id: '17972'
abstract:
- lang: eng
text: Molecular electronics aims to miniaturize electronic devices by using subnanometre-scale
active components1,2,3. A single-molecule diode, a circuit element that directs
current flow4, was first proposed more than 40 years ago5 and consisted of an
asymmetric molecule comprising a donor–bridge–acceptor architecture to mimic a
semiconductor p–n junction. Several single-molecule diodes have since been realized
in junctions featuring asymmetric molecular backbones6,7,8, molecule–electrode
linkers9 or electrode materials10. Despite these advances, molecular diodes have
had limited potential for applications due to their low conductance, low rectification
ratios, extreme sensitivity to the junction structure and high operating voltages7,8,9,11,12.
Here, we demonstrate a powerful approach to induce current rectification in symmetric
single-molecule junctions using two electrodes of the same metal, but breaking
symmetry by exposing considerably different electrode areas to an ionic solution.
This allows us to control the junction's electrostatic environment in an asymmetric
fashion by simply changing the bias polarity. With this method, we reliably and
reproducibly achieve rectification ratios in excess of 200 at voltages as low
as 370 mV using a symmetric oligomer of thiophene-1,1-dioxide13,14. By taking
advantage of the changes in the junction environment induced by the presence of
an ionic solution, this method provides a general route for tuning nonlinear nanoscale
device phenomena, which could potentially be applied in systems beyond single-molecule
junctions.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Brian
full_name: Capozzi, Brian
last_name: Capozzi
- first_name: Jianlong
full_name: Xia, Jianlong
last_name: Xia
- first_name: Olgun
full_name: Adak, Olgun
last_name: Adak
- first_name: Emma J.
full_name: Dell, Emma J.
last_name: Dell
- first_name: Zhen-Fei
full_name: Liu, Zhen-Fei
last_name: Liu
- first_name: Jeffrey C.
full_name: Taylor, Jeffrey C.
last_name: Taylor
- first_name: Jeffrey B.
full_name: Neaton, Jeffrey B.
last_name: Neaton
- first_name: Luis M.
full_name: Campos, Luis M.
last_name: Campos
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
citation:
ama: Capozzi B, Xia J, Adak O, et al. Single-molecule diodes with high rectification
ratios through environmental control. Nature Nanotechnology. 2015;10(6):522-527.
doi:10.1038/nnano.2015.97
apa: Capozzi, B., Xia, J., Adak, O., Dell, E. J., Liu, Z.-F., Taylor, J. C., … Venkataraman,
L. (2015). Single-molecule diodes with high rectification ratios through environmental
control. Nature Nanotechnology. Springer Nature. https://doi.org/10.1038/nnano.2015.97
chicago: Capozzi, Brian, Jianlong Xia, Olgun Adak, Emma J. Dell, Zhen-Fei Liu, Jeffrey
C. Taylor, Jeffrey B. Neaton, Luis M. Campos, and Latha Venkataraman. “Single-Molecule
Diodes with High Rectification Ratios through Environmental Control.” Nature
Nanotechnology. Springer Nature, 2015. https://doi.org/10.1038/nnano.2015.97.
ieee: B. Capozzi et al., “Single-molecule diodes with high rectification
ratios through environmental control,” Nature Nanotechnology, vol. 10,
no. 6. Springer Nature, pp. 522–527, 2015.
ista: Capozzi B, Xia J, Adak O, Dell EJ, Liu Z-F, Taylor JC, Neaton JB, Campos LM,
Venkataraman L. 2015. Single-molecule diodes with high rectification ratios through
environmental control. Nature Nanotechnology. 10(6), 522–527.
mla: Capozzi, Brian, et al. “Single-Molecule Diodes with High Rectification Ratios
through Environmental Control.” Nature Nanotechnology, vol. 10, no. 6,
Springer Nature, 2015, pp. 522–27, doi:10.1038/nnano.2015.97.
short: B. Capozzi, J. Xia, O. Adak, E.J. Dell, Z.-F. Liu, J.C. Taylor, J.B. Neaton,
L.M. Campos, L. Venkataraman, Nature Nanotechnology 10 (2015) 522–527.
date_created: 2024-09-09T10:03:23Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2024-12-18T12:03:16Z
day: '01'
doi: 10.1038/nnano.2015.97
extern: '1'
external_id:
pmid:
- '26005998'
intvolume: ' 10'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 522-527
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-molecule diodes with high rectification ratios through environmental
control
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2015'
...
---
OA_type: closed access
_id: '17999'
abstract:
- lang: eng
text: The idea of using individual molecules as active electronic components provided
the impetus to develop a variety of experimental platforms to probe their electronic
transport properties. Among these, single-molecule junctions in a metal–molecule–metal
motif have contributed significantly to our fundamental understanding of the principles
required to realize molecular-scale electronic components from resistive wires
to reversible switches. The success of these techniques and the growing interest
of other disciplines in single-molecule-level characterization are prompting new
approaches to investigate metal–molecule–metal junctions with multiple probes.
Going beyond electronic transport characterization, these new studies are highlighting
both the fundamental and applied aspects of mechanical, optical and thermoelectric
properties at the atomic and molecular scales. Furthermore, experimental demonstrations
of quantum interference and manipulation of electronic and nuclear spins in single-molecule
circuits are heralding new device concepts with no classical analogues. In this
Review, we present the emerging methods being used to interrogate multiple properties
in single molecule-based devices, detail how these measurements have advanced
our understanding of the structure–function relationships in molecular junctions,
and discuss the potential for future research and applications.
article_processing_charge: No
article_type: original
author:
- first_name: Sriharsha V.
full_name: Aradhya, Sriharsha V.
last_name: Aradhya
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
citation:
ama: Aradhya SV, Venkataraman L. Single-molecule junctions beyond electronic transport.
Nature Nanotechnology. 2013;8(6):399-410. doi:10.1038/nnano.2013.91
apa: Aradhya, S. V., & Venkataraman, L. (2013). Single-molecule junctions beyond
electronic transport. Nature Nanotechnology. Springer Nature. https://doi.org/10.1038/nnano.2013.91
chicago: Aradhya, Sriharsha V., and Latha Venkataraman. “Single-Molecule Junctions
beyond Electronic Transport.” Nature Nanotechnology. Springer Nature, 2013.
https://doi.org/10.1038/nnano.2013.91.
ieee: S. V. Aradhya and L. Venkataraman, “Single-molecule junctions beyond electronic
transport,” Nature Nanotechnology, vol. 8, no. 6. Springer Nature, pp.
399–410, 2013.
ista: Aradhya SV, Venkataraman L. 2013. Single-molecule junctions beyond electronic
transport. Nature Nanotechnology. 8(6), 399–410.
mla: Aradhya, Sriharsha V., and Latha Venkataraman. “Single-Molecule Junctions beyond
Electronic Transport.” Nature Nanotechnology, vol. 8, no. 6, Springer Nature,
2013, pp. 399–410, doi:10.1038/nnano.2013.91.
short: S.V. Aradhya, L. Venkataraman, Nature Nanotechnology 8 (2013) 399–410.
date_created: 2024-09-09T11:35:13Z
date_published: 2013-06-01T00:00:00Z
date_updated: 2025-01-03T08:10:06Z
day: '01'
doi: 10.1038/nnano.2013.91
extern: '1'
external_id:
pmid:
- '23736215'
intvolume: ' 8'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 399-410
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-molecule junctions beyond electronic transport
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2013'
...
---
OA_type: closed access
_id: '18007'
abstract:
- lang: eng
text: According to Kirchhoff's circuit laws, the net conductance of two parallel
components in an electronic circuit is the sum of the individual conductances.
However, when the circuit dimensions are comparable to the electronic phase coherence
length, quantum interference effects play a critical role1, as exemplified by
the Aharonov–Bohm effect in metal rings2,3. At the molecular scale, interference
effects dramatically reduce the electron transfer rate through a meta-connected
benzene ring when compared with a para-connected benzene ring4,5. For longer conjugated
and cross-conjugated molecules, destructive interference effects have been observed
in the tunnelling conductance through molecular junctions6,7,8,9,10. Here, we
investigate the conductance superposition law for parallel components in single-molecule
circuits, particularly the role of interference. We synthesize a series of molecular
systems that contain either one backbone or two backbones in parallel, bonded
together cofacially by a common linker on each end. Single-molecule conductance
measurements and transport calculations based on density functional theory show
that the conductance of a double-backbone molecular junction can be more than
twice that of a single-backbone junction, providing clear evidence for constructive
interference.
article_processing_charge: No
article_type: original
author:
- first_name: H.
full_name: Vazquez, H.
last_name: Vazquez
- first_name: R.
full_name: Skouta, R.
last_name: Skouta
- first_name: S.
full_name: Schneebeli, S.
last_name: Schneebeli
- first_name: M.
full_name: Kamenetska, M.
last_name: Kamenetska
- first_name: R.
full_name: Breslow, R.
last_name: Breslow
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
- first_name: M.S.
full_name: Hybertsen, M.S.
last_name: Hybertsen
citation:
ama: Vazquez H, Skouta R, Schneebeli S, et al. Probing the conductance superposition
law in single-molecule circuits with parallel paths. Nature Nanotechnology.
2012;7(10):663-667. doi:10.1038/nnano.2012.147
apa: Vazquez, H., Skouta, R., Schneebeli, S., Kamenetska, M., Breslow, R., Venkataraman,
L., & Hybertsen, M. S. (2012). Probing the conductance superposition law in
single-molecule circuits with parallel paths. Nature Nanotechnology. Springer
Nature. https://doi.org/10.1038/nnano.2012.147
chicago: Vazquez, H., R. Skouta, S. Schneebeli, M. Kamenetska, R. Breslow, Latha
Venkataraman, and M.S. Hybertsen. “Probing the Conductance Superposition Law in
Single-Molecule Circuits with Parallel Paths.” Nature Nanotechnology. Springer
Nature, 2012. https://doi.org/10.1038/nnano.2012.147.
ieee: H. Vazquez et al., “Probing the conductance superposition law in single-molecule
circuits with parallel paths,” Nature Nanotechnology, vol. 7, no. 10. Springer
Nature, pp. 663–667, 2012.
ista: Vazquez H, Skouta R, Schneebeli S, Kamenetska M, Breslow R, Venkataraman L,
Hybertsen MS. 2012. Probing the conductance superposition law in single-molecule
circuits with parallel paths. Nature Nanotechnology. 7(10), 663–667.
mla: Vazquez, H., et al. “Probing the Conductance Superposition Law in Single-Molecule
Circuits with Parallel Paths.” Nature Nanotechnology, vol. 7, no. 10, Springer
Nature, 2012, pp. 663–67, doi:10.1038/nnano.2012.147.
short: H. Vazquez, R. Skouta, S. Schneebeli, M. Kamenetska, R. Breslow, L. Venkataraman,
M.S. Hybertsen, Nature Nanotechnology 7 (2012) 663–667.
date_created: 2024-09-09T12:28:28Z
date_published: 2012-09-02T00:00:00Z
date_updated: 2025-01-03T09:07:44Z
day: '02'
doi: 10.1038/nnano.2012.147
extern: '1'
external_id:
pmid:
- '22941403'
intvolume: ' 7'
issue: '10'
language:
- iso: eng
month: '09'
oa_version: None
page: 663-667
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Probing the conductance superposition law in single-molecule circuits with
parallel paths
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2012'
...
---
OA_type: closed access
_id: '18021'
abstract:
- lang: eng
text: Charge transport across metal–molecule interfaces has an important role in
organic electronics1. Typically, chemical link groups such as thiols2 or amines3
are used to bind organic molecules to metal electrodes in single-molecule circuits,
with these groups controlling both the physical structure and the electronic coupling
at the interface. Direct metal–carbon coupling has been shown through C60, benzene
and π-stacked benzene4,5,6,7, but ideally the carbon backbone of the molecule
should be covalently bonded to the electrode without intervening link groups.
Here, we demonstrate a method to create junctions with such contacts. Trimethyl
tin (SnMe3)-terminated polymethylene chains are used to form single-molecule junctions
with a break-junction technique2,3. Gold atoms at the electrode displace the SnMe3
linkers, leading to the formation of direct Au–C bonded single-molecule junctions
with a conductance that is ∼100 times larger than analogous alkanes with most
other terminations. The conductance of these Au–C bonded alkanes decreases exponentially
with molecular length, with a decay constant of 0.97 per methylene, consistent
with a non-resonant transport mechanism. Control experiments and ab initio calculations
show that high conductances are achieved because a covalent Au–C sigma (σ) bond
is formed. This offers a new method for making reproducible and highly conducting
metal–organic contacts.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Z.-L.
full_name: Cheng, Z.-L.
last_name: Cheng
- first_name: R.
full_name: Skouta, R.
last_name: Skouta
- first_name: H.
full_name: Vazquez, H.
last_name: Vazquez
- first_name: J. R.
full_name: Widawsky, J. R.
last_name: Widawsky
- first_name: S.
full_name: Schneebeli, S.
last_name: Schneebeli
- first_name: W.
full_name: Chen, W.
last_name: Chen
- first_name: M. S.
full_name: Hybertsen, M. S.
last_name: Hybertsen
- first_name: R.
full_name: Breslow, R.
last_name: Breslow
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
citation:
ama: Cheng Z-L, Skouta R, Vazquez H, et al. In situ formation of highly conducting
covalent Au–C contacts for single-molecule junctions. Nature Nanotechnology.
2011;6(6):353-357. doi:10.1038/nnano.2011.66
apa: Cheng, Z.-L., Skouta, R., Vazquez, H., Widawsky, J. R., Schneebeli, S., Chen,
W., … Venkataraman, L. (2011). In situ formation of highly conducting covalent
Au–C contacts for single-molecule junctions. Nature Nanotechnology. Springer
Nature. https://doi.org/10.1038/nnano.2011.66
chicago: Cheng, Z.-L., R. Skouta, H. Vazquez, J. R. Widawsky, S. Schneebeli, W.
Chen, M. S. Hybertsen, R. Breslow, and Latha Venkataraman. “In Situ Formation
of Highly Conducting Covalent Au–C Contacts for Single-Molecule Junctions.” Nature
Nanotechnology. Springer Nature, 2011. https://doi.org/10.1038/nnano.2011.66.
ieee: Z.-L. Cheng et al., “In situ formation of highly conducting covalent
Au–C contacts for single-molecule junctions,” Nature Nanotechnology, vol.
6, no. 6. Springer Nature, pp. 353–357, 2011.
ista: Cheng Z-L, Skouta R, Vazquez H, Widawsky JR, Schneebeli S, Chen W, Hybertsen
MS, Breslow R, Venkataraman L. 2011. In situ formation of highly conducting covalent
Au–C contacts for single-molecule junctions. Nature Nanotechnology. 6(6), 353–357.
mla: Cheng, Z. L., et al. “In Situ Formation of Highly Conducting Covalent Au–C
Contacts for Single-Molecule Junctions.” Nature Nanotechnology, vol. 6,
no. 6, Springer Nature, 2011, pp. 353–57, doi:10.1038/nnano.2011.66.
short: Z.-L. Cheng, R. Skouta, H. Vazquez, J.R. Widawsky, S. Schneebeli, W. Chen,
M.S. Hybertsen, R. Breslow, L. Venkataraman, Nature Nanotechnology 6 (2011) 353–357.
date_created: 2024-09-09T12:57:48Z
date_published: 2011-06-01T00:00:00Z
date_updated: 2025-01-03T09:51:33Z
day: '01'
doi: 10.1038/nnano.2011.66
extern: '1'
external_id:
pmid:
- '21552252'
intvolume: ' 6'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 353-357
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: In situ formation of highly conducting covalent Au–C contacts for single-molecule
junctions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2011'
...
---
OA_place: repository
OA_type: green
_id: '18031'
abstract:
- lang: eng
text: 'Molecular-scale components are expected to be central to the realization
of nanoscale electronic devices1,2,3. Although molecular-scale switching has been
reported in atomic quantum point contacts4,5,6, single-molecule junctions provide
the additional flexibility of tuning the on/off conductance states through molecular
design. To date, switching in single-molecule junctions has been attributed to
changes in the conformation or charge state of the molecule7,8,9,10,11,12. Here,
we demonstrate reversible binary switching in a single-molecule junction by mechanical
control of the metal–molecule contact geometry. We show that 4,4''-bipyridine–gold
single-molecule junctions can be reversibly switched between two conductance states
through repeated junction elongation and compression. Using first-principles calculations,
we attribute the different measured conductance states to distinct contact geometries
at the flexible but stable nitrogen–gold bond: conductance is low when the N–Au
bond is perpendicular to the conducting π-system, and high otherwise. This switching
mechanism, inherent to the pyridine–gold link, could form the basis of a new class
of mechanically activated single-molecule switches.'
article_processing_charge: No
article_type: letter_note
arxiv: 1
author:
- first_name: Su Ying
full_name: Quek, Su Ying
last_name: Quek
- first_name: Maria
full_name: Kamenetska, Maria
last_name: Kamenetska
- first_name: Michael L.
full_name: Steigerwald, Michael L.
last_name: Steigerwald
- first_name: Hyoung Joon
full_name: Choi, Hyoung Joon
last_name: Choi
- first_name: Steven G.
full_name: Louie, Steven G.
last_name: Louie
- first_name: Mark S.
full_name: Hybertsen, Mark S.
last_name: Hybertsen
- first_name: J. B.
full_name: Neaton, J. B.
last_name: Neaton
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
citation:
ama: Quek SY, Kamenetska M, Steigerwald ML, et al. Mechanically controlled binary
conductance switching of a single-molecule junction. Nature Nanotechnology.
2009;4(4):230-234. doi:10.1038/nnano.2009.10
apa: Quek, S. Y., Kamenetska, M., Steigerwald, M. L., Choi, H. J., Louie, S. G.,
Hybertsen, M. S., … Venkataraman, L. (2009). Mechanically controlled binary conductance
switching of a single-molecule junction. Nature Nanotechnology. Springer
Nature. https://doi.org/10.1038/nnano.2009.10
chicago: Quek, Su Ying, Maria Kamenetska, Michael L. Steigerwald, Hyoung Joon Choi,
Steven G. Louie, Mark S. Hybertsen, J. B. Neaton, and Latha Venkataraman. “Mechanically
Controlled Binary Conductance Switching of a Single-Molecule Junction.” Nature
Nanotechnology. Springer Nature, 2009. https://doi.org/10.1038/nnano.2009.10.
ieee: S. Y. Quek et al., “Mechanically controlled binary conductance switching
of a single-molecule junction,” Nature Nanotechnology, vol. 4, no. 4. Springer
Nature, pp. 230–234, 2009.
ista: Quek SY, Kamenetska M, Steigerwald ML, Choi HJ, Louie SG, Hybertsen MS, Neaton
JB, Venkataraman L. 2009. Mechanically controlled binary conductance switching
of a single-molecule junction. Nature Nanotechnology. 4(4), 230–234.
mla: Quek, Su Ying, et al. “Mechanically Controlled Binary Conductance Switching
of a Single-Molecule Junction.” Nature Nanotechnology, vol. 4, no. 4, Springer
Nature, 2009, pp. 230–34, doi:10.1038/nnano.2009.10.
short: S.Y. Quek, M. Kamenetska, M.L. Steigerwald, H.J. Choi, S.G. Louie, M.S. Hybertsen,
J.B. Neaton, L. Venkataraman, Nature Nanotechnology 4 (2009) 230–234.
date_created: 2024-09-09T13:53:36Z
date_published: 2009-04-01T00:00:00Z
date_updated: 2025-01-03T10:42:35Z
day: '01'
doi: 10.1038/nnano.2009.10
extern: '1'
external_id:
arxiv:
- '0901.1139'
pmid:
- '19350032'
intvolume: ' 4'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/0901.1139
month: '04'
oa: 1
oa_version: Preprint
page: 230-234
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanically controlled binary conductance switching of a single-molecule junction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2009'
...
---
OA_type: closed access
_id: '18034'
abstract:
- lang: eng
text: The ability to perform optical measurements on a single molecule placed between
two electrodes while also measuring the current flowing through it could herald
a new generation of experiments on molecular junctions.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Latha
full_name: Venkataraman, Latha
id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
last_name: Venkataraman
orcid: 0000-0002-6957-6089
citation:
ama: Venkataraman L. Seeing is believing. Nature Nanotechnology. 2008;3(4):187-188.
doi:10.1038/nnano.2008.81
apa: Venkataraman, L. (2008). Seeing is believing. Nature Nanotechnology.
Springer Nature. https://doi.org/10.1038/nnano.2008.81
chicago: Venkataraman, Latha. “Seeing Is Believing.” Nature Nanotechnology.
Springer Nature, 2008. https://doi.org/10.1038/nnano.2008.81.
ieee: L. Venkataraman, “Seeing is believing,” Nature Nanotechnology, vol.
3, no. 4. Springer Nature, pp. 187–188, 2008.
ista: Venkataraman L. 2008. Seeing is believing. Nature Nanotechnology. 3(4), 187–188.
mla: Venkataraman, Latha. “Seeing Is Believing.” Nature Nanotechnology, vol.
3, no. 4, Springer Nature, 2008, pp. 187–88, doi:10.1038/nnano.2008.81.
short: L. Venkataraman, Nature Nanotechnology 3 (2008) 187–188.
date_created: 2024-09-09T14:26:30Z
date_published: 2008-04-01T00:00:00Z
date_updated: 2025-01-03T10:57:41Z
day: '01'
doi: 10.1038/nnano.2008.81
extern: '1'
external_id:
pmid:
- '18654498'
intvolume: ' 3'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 187-188
pmid: 1
publication: Nature Nanotechnology
publication_identifier:
eissn:
- 1748-3395
issn:
- 1748-3387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Seeing is believing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2008'
...