---
OA_place: publisher
OA_type: gold
_id: '19370'
abstract:
- lang: eng
text: Sex-linked and autosomal loci experience different selective pressures and
evolutionary dynamics. X (or Z) chromosomes are often hemizygous in males (or
females), as Y (or W) chromosomes often degenerate. Such hemizygous regions can
be under greater efficacy of selection, as recessive mutations are immediately
exposed to selection in the heterogametic sex leading to faster adaptation and
faster divergence on the X chromosome (the so-called Faster-X or Faster-Z effect).
However, in young nonrecombining regions, Y/W chromosomes often have many functional
genes, and many X/Z-linked loci are therefore diploid. The sheltering of recessive
mutations on the X/Z by the Y/W homolog is expected to drive slower adaptation
for diploid X/Z loci, i.e. a reduction in the efficacy of selection. While the
Faster-X effect has been studied extensively, much less is known empirically about
the evolutionary dynamics of diploid X or Z chromosomes. Here, we took advantage
of published population genomic data in the female-heterogametic human parasite
Schistosoma japonicum to characterize the gene content and diversity levels of
the diploid and hemizygous regions of the Z chromosome. We used different metrics
of selective pressures acting on genes to test for differences in the efficacy
of selection in hemizygous and diploid Z regions, relative to autosomes. We found
consistent patterns suggesting reduced Ne, and reduced efficacy of purifying selection,
on both hemizygous and diploid Z regions. Moreover, relaxed selection was particularly
pronounced for female-biased genes on the diploid Z, as predicted by recent theoretical
work.
acknowledgement: The authors would like to thank three anonymous reviewers for comments
and suggestions. We are also grateful to Christelle Fraïsse, Marwan Elkrewi, and
Filip Ruzicka for the help in this project.
article_number: evaf021
article_processing_charge: Yes
article_type: original
author:
- first_name: Andrea
full_name: Mrnjavac, Andrea
id: 353FAC84-AE61-11E9-8BFC-00D3E5697425
last_name: Mrnjavac
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: Mrnjavac A, Vicoso B. Reduced efficacy of selection on a young Z chromosome
region of schistosoma japonicum. Genome Biology and Evolution. 2025;17(2).
doi:10.1093/gbe/evaf021
apa: Mrnjavac, A., & Vicoso, B. (2025). Reduced efficacy of selection on a young
Z chromosome region of schistosoma japonicum. Genome Biology and Evolution.
Oxford University Press. https://doi.org/10.1093/gbe/evaf021
chicago: Mrnjavac, Andrea, and Beatriz Vicoso. “Reduced Efficacy of Selection on
a Young Z Chromosome Region of Schistosoma Japonicum.” Genome Biology and Evolution.
Oxford University Press, 2025. https://doi.org/10.1093/gbe/evaf021.
ieee: A. Mrnjavac and B. Vicoso, “Reduced efficacy of selection on a young Z chromosome
region of schistosoma japonicum,” Genome Biology and Evolution, vol. 17,
no. 2. Oxford University Press, 2025.
ista: Mrnjavac A, Vicoso B. 2025. Reduced efficacy of selection on a young Z chromosome
region of schistosoma japonicum. Genome Biology and Evolution. 17(2), evaf021.
mla: Mrnjavac, Andrea, and Beatriz Vicoso. “Reduced Efficacy of Selection on a Young
Z Chromosome Region of Schistosoma Japonicum.” Genome Biology and Evolution,
vol. 17, no. 2, evaf021, Oxford University Press, 2025, doi:10.1093/gbe/evaf021.
short: A. Mrnjavac, B. Vicoso, Genome Biology and Evolution 17 (2025).
corr_author: '1'
date_created: 2025-03-09T23:01:27Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2025-09-30T10:49:17Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evaf021
external_id:
isi:
- '001423671400001'
pmid:
- '39913672'
file:
- access_level: open_access
checksum: e3aa993e3d6dad10cb806c243fa57408
content_type: application/pdf
creator: dernst
date_created: 2025-03-10T08:25:59Z
date_updated: 2025-03-10T08:25:59Z
file_id: '19378'
file_name: 2025_GBE_Mrnjavac.pdf
file_size: 768371
relation: main_file
success: 1
file_date_updated: 2025-03-10T08:25:59Z
has_accepted_license: '1'
intvolume: ' 17'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology and Evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://git.ista.ac.at/amrnjava/schistosomes_slower_z
record:
- id: '18549'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Reduced efficacy of selection on a young Z chromosome region of schistosoma
japonicum
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 17
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18761'
abstract:
- lang: eng
text: Termites, together with cockroaches, belong to the Blattodea. They possess
an XX/XY sex determination system which has evolved from an XX/X0 system present
in other Blattodean species, such as cockroaches and wood roaches. Little is currently
known about the sex chromosomes of termites, their gene content, or their evolution.
We here investigate the X chromosome of multiple termite species and compare them
with the X chromosome of cockroaches using genomic and transcriptomic data. We
find that the X chromosome of the termite Macrotermes natalensis is large and
differentiated showing hall marks of sex chromosome evolution such as dosage compensation,
while this does not seem to be the case in the other two termite species investigated
here where sex chromosomes may be evolutionary younger. Furthermore, the X chromosome
in M. natalensis is different from the X chromosome found in the cockroach Blattella
germanica indicating that sex chromosome turn-over events may have happened during
termite evolution.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "urthermore, we thank all lab members and collaborators for feedback
on the project. Specifically, Dino McMahon provided R. flavipes males and females,
Judith Korb provided C. secundus males and females, gave feedback on the project
and discussed questions on termite reproduction, Mireille Vasseur-Cognet provided
M. natalensis males and females, Ariana Macon performed the lab work for sequencing
and the Vicoso group gave critical feedback on the project. We furthermore thank
the HPC group at IST Austria and Christian Meesters at JGU Mainz for their technical
support.\r\nThis work was supported by a Österreichischer Wissenschaftsfonds (FWF)
grant of the Meitner Programme to A.K.H. (project number M 2484), funding by the
Deutsche Forschungsgemeinschaft (DFG) of the Research Training Group GenEvo (project
number 407023052) to A.K.H., R.F., and A.D., and funding of the DFG within the Schwerpunktprogramm
Gevol to A.K.H. and R.M. (project number 503256468)."
article_number: evae265
article_processing_charge: Yes
article_type: original
author:
- first_name: Roxanne
full_name: Fraser, Roxanne
last_name: Fraser
- first_name: Ruth
full_name: Moraa, Ruth
last_name: Moraa
- first_name: Annika
full_name: Djolai, Annika
last_name: Djolai
- first_name: Nils
full_name: Meisenheimer, Nils
last_name: Meisenheimer
- first_name: Sophie
full_name: Laube, Sophie
last_name: Laube
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Ann K
full_name: Huylmans, Ann K
id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
last_name: Huylmans
orcid: 0000-0001-8871-4961
citation:
ama: Fraser R, Moraa R, Djolai A, et al. Evidence for a novel X chromosome in termites.
Genome Biology and Evolution. 2024;16(12). doi:10.1093/gbe/evae265
apa: Fraser, R., Moraa, R., Djolai, A., Meisenheimer, N., Laube, S., Vicoso, B.,
& Huylmans, A. K. (2024). Evidence for a novel X chromosome in termites. Genome
Biology and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evae265
chicago: Fraser, Roxanne, Ruth Moraa, Annika Djolai, Nils Meisenheimer, Sophie Laube,
Beatriz Vicoso, and Ann K Huylmans. “Evidence for a Novel X Chromosome in Termites.”
Genome Biology and Evolution. Oxford University Press, 2024. https://doi.org/10.1093/gbe/evae265.
ieee: R. Fraser et al., “Evidence for a novel X chromosome in termites,”
Genome Biology and Evolution, vol. 16, no. 12. Oxford University Press,
2024.
ista: Fraser R, Moraa R, Djolai A, Meisenheimer N, Laube S, Vicoso B, Huylmans AK.
2024. Evidence for a novel X chromosome in termites. Genome Biology and Evolution.
16(12), evae265.
mla: Fraser, Roxanne, et al. “Evidence for a Novel X Chromosome in Termites.” Genome
Biology and Evolution, vol. 16, no. 12, evae265, Oxford University Press,
2024, doi:10.1093/gbe/evae265.
short: R. Fraser, R. Moraa, A. Djolai, N. Meisenheimer, S. Laube, B. Vicoso, A.K.
Huylmans, Genome Biology and Evolution 16 (2024).
corr_author: '1'
date_created: 2025-01-05T23:01:58Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-09-09T11:58:41Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evae265
external_id:
isi:
- '001380841100001'
pmid:
- '39658246'
file:
- access_level: open_access
checksum: 9cf8fd14580dd694dd810ccca808ad0e
content_type: application/pdf
creator: dernst
date_created: 2025-01-08T08:28:07Z
date_updated: 2025-01-08T08:28:07Z
file_id: '18772'
file_name: 2024_GBE_Fraser.pdf
file_size: 795106
relation: main_file
success: 1
file_date_updated: 2025-01-08T08:28:07Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26641CAC-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02484
name: Sex Determination in Termites
publication: Genome Biology and Evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evidence for a novel X chromosome in termites
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 16
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '15009'
abstract:
- lang: eng
text: Since the commercialization of brine shrimp (genus Artemia) in the 1950s,
this lineage, and in particular the model species Artemia franciscana, has been
the subject of extensive research. However, our understanding of the genetic mechanisms
underlying various aspects of their reproductive biology, including sex determination,
is still lacking. This is partly due to the scarcity of genomic resources for
Artemia species and crustaceans in general. Here, we present a chromosome-level
genome assembly of A. franciscana (Kellogg 1906), from the Great Salt Lake, United
States. The genome is 1 GB, and the majority of the genome (81%) is scaffolded
into 21 linkage groups using a previously published high-density linkage map.
We performed coverage and FST analyses using male and female genomic and transcriptomic
reads to quantify the extent of differentiation between the Z and W chromosomes.
Additionally, we quantified the expression levels in male and female heads and
gonads and found further evidence for dosage compensation in this species.
article_number: evae006
article_processing_charge: Yes
article_type: original
author:
- first_name: Vincent K
full_name: Bett, Vincent K
id: 57854184-AAE0-11E9-8D04-98D6E5697425
last_name: Bett
- first_name: Ariana
full_name: Macon, Ariana
id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
last_name: Macon
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Marwan N
full_name: Elkrewi, Marwan N
id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
last_name: Elkrewi
orcid: 0000-0002-5328-7231
citation:
ama: Bett VK, Macon A, Vicoso B, Elkrewi MN. Chromosome-level assembly of Artemia
franciscana sheds light on sex chromosome differentiation. Genome Biology and
Evolution. 2024;16(1). doi:10.1093/gbe/evae006
apa: Bett, V. K., Macon, A., Vicoso, B., & Elkrewi, M. N. (2024). Chromosome-level
assembly of Artemia franciscana sheds light on sex chromosome differentiation.
Genome Biology and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evae006
chicago: Bett, Vincent K, Ariana Macon, Beatriz Vicoso, and Marwan N Elkrewi. “Chromosome-Level
Assembly of Artemia Franciscana Sheds Light on Sex Chromosome Differentiation.”
Genome Biology and Evolution. Oxford University Press, 2024. https://doi.org/10.1093/gbe/evae006.
ieee: V. K. Bett, A. Macon, B. Vicoso, and M. N. Elkrewi, “Chromosome-level assembly
of Artemia franciscana sheds light on sex chromosome differentiation,” Genome
Biology and Evolution, vol. 16, no. 1. Oxford University Press, 2024.
ista: Bett VK, Macon A, Vicoso B, Elkrewi MN. 2024. Chromosome-level assembly of
Artemia franciscana sheds light on sex chromosome differentiation. Genome Biology
and Evolution. 16(1), evae006.
mla: Bett, Vincent K., et al. “Chromosome-Level Assembly of Artemia Franciscana
Sheds Light on Sex Chromosome Differentiation.” Genome Biology and Evolution,
vol. 16, no. 1, evae006, Oxford University Press, 2024, doi:10.1093/gbe/evae006.
short: V.K. Bett, A. Macon, B. Vicoso, M.N. Elkrewi, Genome Biology and Evolution
16 (2024).
corr_author: '1'
date_created: 2024-02-18T23:01:02Z
date_published: 2024-01-20T00:00:00Z
date_updated: 2026-05-03T22:31:09Z
day: '20'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evae006
external_id:
isi:
- '001153952800001'
pmid:
- '38245839'
file:
- access_level: open_access
checksum: 106a40f10443b2e7ba66749844ebbdf1
content_type: application/pdf
creator: dernst
date_created: 2024-02-26T09:54:59Z
date_updated: 2024-02-26T09:54:59Z
file_id: '15029'
file_name: 2024_GBE_Bett.pdf
file_size: 5213306
relation: main_file
success: 1
file_date_updated: 2024-02-26T09:54:59Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology and Evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
record:
- id: '14705'
relation: research_data
status: public
- id: '20444'
relation: dissertation_contains
status: private
- id: '20449'
relation: dissertation_contains
status: public
- id: '19386'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Chromosome-level assembly of Artemia franciscana sheds light on sex chromosome
differentiation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 16
year: '2024'
...
---
_id: '13260'
abstract:
- lang: eng
text: Experimental evolution studies are powerful approaches to examine the evolutionary
history of lab populations. Such studies have shed light on how selection changes
phenotypes and genotypes. Most of these studies have not examined the time course
of adaptation under sexual selection manipulation, by resequencing the populations’
genomes at multiple time points. Here, we analyze allele frequency trajectories
in Drosophila pseudoobscura where we altered their sexual selection regime for
200 generations and sequenced pooled populations at 5 time points. The intensity
of sexual selection was either relaxed in monogamous populations (M) or elevated
in polyandrous lines (E). We present a comprehensive study of how selection alters
population genetics parameters at the chromosome and gene level. We investigate
differences in the effective population size—Ne—between the treatments, and perform
a genome-wide scan to identify signatures of selection from the time-series data.
We found genomic signatures of adaptation to both regimes in D. pseudoobscura.
There are more significant variants in E lines as expected from stronger sexual
selection. However, we found that the response on the X chromosome was substantial
in both treatments, more pronounced in E and restricted to the more recently sex-linked
chromosome arm XR in M. In the first generations of experimental evolution, we
estimate Ne to be lower on the X in E lines, which might indicate a swift adaptive
response at the onset of selection. Additionally, the third chromosome was affected
by elevated polyandry whereby its distal end harbors a region showing a strong
signal of adaptive evolution especially in E lines.
acknowledgement: This work was supported by the Vienna Science and Technology Fund
(WWTF)(10.47379/MA16061). C.K. received funding from the Royal Society (RG170315)
and the Carnegie Trust (RIG007474). M.G.R. and R.R.S. have been supported by NERC
(UK) grants NE/I014632/1 and NE/V001566/1. Bioinformatics analyses were performed
on the computer cluster at the University of St Andrews Bioinformatics Unit, which
is funded by Wellcome Trust ISSF awards 105621/Z/14/Z. Complementary data parsing
was carried out with the computational resources provided by the Research/Scientific
Computing teams at The James Hutton Institute and the National Institute of Agricultural
Botany (NIAB)—UK’s Crop Diversity Bioinformatics HPC, BBSRC grant BB/S019669/1.
We are thankful to Paris Veltsos and R. Axel W. Wiberg for useful discussions about
the project as well as providing us with the resequencing data they had produced
as a result of previous work on this experiment. We are especially grateful to Tanya
Sneddon for her help with the DNA extraction process and shipping.
article_number: evad113
article_processing_charge: Yes
article_type: original
author:
- first_name: Carolina
full_name: De Castro Barbosa Rodrigues Barata, Carolina
id: 20565186-803f-11ed-ab7e-96a4ff7694ef
last_name: De Castro Barbosa Rodrigues Barata
orcid: 0000-0003-1945-2245
- first_name: Rhonda R.
full_name: Snook, Rhonda R.
last_name: Snook
- first_name: Michael G.
full_name: Ritchie, Michael G.
last_name: Ritchie
- first_name: Carolin
full_name: Kosiol, Carolin
last_name: Kosiol
citation:
ama: 'de Castro Barbosa Rodrigues Barata C, Snook RR, Ritchie MG, Kosiol C. Selection
on the fly: Short-term adaptation to an altered sexual selection regime in Drosophila
pseudoobscura. Genome biology and evolution. 2023;15(7). doi:10.1093/gbe/evad113'
apa: 'de Castro Barbosa Rodrigues Barata, C., Snook, R. R., Ritchie, M. G., &
Kosiol, C. (2023). Selection on the fly: Short-term adaptation to an altered sexual
selection regime in Drosophila pseudoobscura. Genome Biology and Evolution.
Oxford University Press. https://doi.org/10.1093/gbe/evad113'
chicago: 'Castro Barbosa Rodrigues Barata, Carolina de, Rhonda R. Snook, Michael
G. Ritchie, and Carolin Kosiol. “Selection on the Fly: Short-Term Adaptation to
an Altered Sexual Selection Regime in Drosophila Pseudoobscura.” Genome Biology
and Evolution. Oxford University Press, 2023. https://doi.org/10.1093/gbe/evad113.'
ieee: 'C. de Castro Barbosa Rodrigues Barata, R. R. Snook, M. G. Ritchie, and C.
Kosiol, “Selection on the fly: Short-term adaptation to an altered sexual selection
regime in Drosophila pseudoobscura,” Genome biology and evolution, vol.
15, no. 7. Oxford University Press, 2023.'
ista: 'de Castro Barbosa Rodrigues Barata C, Snook RR, Ritchie MG, Kosiol C. 2023.
Selection on the fly: Short-term adaptation to an altered sexual selection regime
in Drosophila pseudoobscura. Genome biology and evolution. 15(7), evad113.'
mla: 'de Castro Barbosa Rodrigues Barata, Carolina, et al. “Selection on the Fly:
Short-Term Adaptation to an Altered Sexual Selection Regime in Drosophila Pseudoobscura.”
Genome Biology and Evolution, vol. 15, no. 7, evad113, Oxford University
Press, 2023, doi:10.1093/gbe/evad113.'
short: C. de Castro Barbosa Rodrigues Barata, R.R. Snook, M.G. Ritchie, C. Kosiol,
Genome Biology and Evolution 15 (2023).
corr_author: '1'
date_created: 2023-07-23T22:01:11Z
date_published: 2023-07-01T00:00:00Z
date_updated: 2025-05-14T11:08:37Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evad113
external_id:
isi:
- '001023444700003'
pmid:
- '37341535'
file:
- access_level: open_access
checksum: 70de3c4878de6efe00dc56de2df8812f
content_type: application/pdf
creator: dernst
date_created: 2023-08-01T06:58:34Z
date_updated: 2023-08-01T06:58:34Z
file_id: '13339'
file_name: 2023_GBE_Barata.pdf
file_size: 2382587
relation: main_file
success: 1
file_date_updated: 2023-08-01T06:58:34Z
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome biology and evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://github.com/carolbarata/dpseudo-n-beyond
scopus_import: '1'
status: public
title: 'Selection on the fly: Short-term adaptation to an altered sexual selection
regime in Drosophila pseudoobscura'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2023'
...
---
_id: '6418'
abstract:
- lang: eng
text: Males and females of Artemia franciscana, a crustacean commonly used in the
aquarium trade, are highly dimorphic. Sex is determined by a pair of ZW chromosomes,
but the nature and extent of differentiation of these chromosomes is unknown.
Here, we characterize the Z chromosome by detecting genomic regions that show
lower genomic coverage in female than in male samples, and regions that harbor
an excess of female-specific SNPs. We detect many Z-specific genes, which no longer
have homologs on the W, but also Z-linked genes that appear to have diverged very
recently from their existing W-linked homolog. We assess patterns of male and
female expression in two tissues with extensive morphological dimorphism, gonads,
and heads. In agreement with their morphology, sex-biased expression is common
in both tissues. Interestingly, the Z chromosome is not enriched for sex-biased
genes, and seems to in fact have a mechanism of dosage compensation that leads
to equal expression in males and in females. Both of these patterns are contrary
to most ZW systems studied so far, making A. franciscana an excellent model for
investigating the interplay between the evolution of sexual dimorphism and dosage
compensation, as well as Z chromosome evolution in general.
acknowledged_ssus:
- _id: ScienComp
article_processing_charge: No
author:
- first_name: Ann K
full_name: Huylmans, Ann K
id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
last_name: Huylmans
orcid: 0000-0001-8871-4961
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Ariana
full_name: Macon, Ariana
id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
last_name: Macon
- first_name: William J
full_name: Gammerdinger, William J
id: 3A7E01BC-F248-11E8-B48F-1D18A9856A87
last_name: Gammerdinger
orcid: 0000-0001-9638-1220
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: Huylmans AK, Toups MA, Macon A, Gammerdinger WJ, Vicoso B. Sex-biased gene
expression and dosage compensation on the Artemia franciscana Z-chromosome. Genome
biology and evolution. 2019;11(4):1033-1044. doi:10.1093/gbe/evz053
apa: Huylmans, A. K., Toups, M. A., Macon, A., Gammerdinger, W. J., & Vicoso,
B. (2019). Sex-biased gene expression and dosage compensation on the Artemia franciscana
Z-chromosome. Genome Biology and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evz053
chicago: Huylmans, Ann K, Melissa A Toups, Ariana Macon, William J Gammerdinger,
and Beatriz Vicoso. “Sex-Biased Gene Expression and Dosage Compensation on the
Artemia Franciscana Z-Chromosome.” Genome Biology and Evolution. Oxford
University Press, 2019. https://doi.org/10.1093/gbe/evz053.
ieee: A. K. Huylmans, M. A. Toups, A. Macon, W. J. Gammerdinger, and B. Vicoso,
“Sex-biased gene expression and dosage compensation on the Artemia franciscana
Z-chromosome,” Genome biology and evolution, vol. 11, no. 4. Oxford University
Press, pp. 1033–1044, 2019.
ista: Huylmans AK, Toups MA, Macon A, Gammerdinger WJ, Vicoso B. 2019. Sex-biased
gene expression and dosage compensation on the Artemia franciscana Z-chromosome.
Genome biology and evolution. 11(4), 1033–1044.
mla: Huylmans, Ann K., et al. “Sex-Biased Gene Expression and Dosage Compensation
on the Artemia Franciscana Z-Chromosome.” Genome Biology and Evolution,
vol. 11, no. 4, Oxford University Press, 2019, pp. 1033–44, doi:10.1093/gbe/evz053.
short: A.K. Huylmans, M.A. Toups, A. Macon, W.J. Gammerdinger, B. Vicoso, Genome
Biology and Evolution 11 (2019) 1033–1044.
date_created: 2019-05-13T07:58:38Z
date_published: 2019-04-01T00:00:00Z
date_updated: 2025-04-14T07:41:21Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evz053
ec_funded: 1
external_id:
isi:
- '000476569800003'
file:
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checksum: 7d0ede297b6741f3dc89cd59017c7642
content_type: application/pdf
creator: dernst
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date_updated: 2020-07-14T12:47:29Z
file_id: '6446'
file_name: 2019_GBE_Huylmans.pdf
file_size: 1256303
relation: main_file
file_date_updated: 2020-07-14T12:47:29Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1033-1044
project:
- _id: 250BDE62-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715257'
name: Prevalence and Influence of Sexual Antagonism on Genome Evolution
publication: Genome biology and evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
record:
- id: '6060'
relation: popular_science
status: public
scopus_import: '1'
status: public
title: Sex-biased gene expression and dosage compensation on the Artemia franciscana
Z-chromosome
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2019'
...
---
_id: '6755'
abstract:
- lang: eng
text: 'Differentiated sex chromosomes are accompanied by a difference in gene dose
between X/Z-specific and autosomal genes. At the transcriptomic level, these sex-linked
genes can lead to expression imbalance, or gene dosage can be compensated by epigenetic
mechanisms and results into expression level equalization. Schistosoma mansoni
has been previously described as a ZW species (i.e., female heterogamety, in opposition
to XY male heterogametic species) with a partial dosage compensation, but underlying
mechanisms are still unexplored. Here, we combine transcriptomic (RNA-Seq) and
epigenetic data (ChIP-Seq against H3K4me3, H3K27me3,andH4K20me1histonemarks) in
free larval cercariae and intravertebrate parasitic stages. For the first time,
we describe differences in dosage compensation status in ZW females, depending
on the parasitic status: free cercariae display global dosage compensation, whereas
intravertebrate stages show a partial dosage compensation. We also highlight regional
differences of gene expression along the Z chromosome in cercariae, but not in
the intravertebrate stages. Finally, we feature a consistent permissive chromatin
landscape of the Z chromosome in both sexes and stages. We argue that dosage compensation
in schistosomes is characterized by chromatin remodeling mechanisms in the Z-specific
region.'
acknowledged_ssus:
- _id: CampIT
article_processing_charge: No
article_type: original
author:
- first_name: Marion A L
full_name: Picard, Marion A L
id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
last_name: Picard
orcid: 0000-0002-8101-2518
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: David
full_name: Roquis, David
last_name: Roquis
- first_name: Ingo
full_name: Bulla, Ingo
last_name: Bulla
- first_name: Ronaldo C.
full_name: Augusto, Ronaldo C.
last_name: Augusto
- first_name: Nathalie
full_name: Arancibia, Nathalie
last_name: Arancibia
- first_name: Christoph
full_name: Grunau, Christoph
last_name: Grunau
- first_name: Jérôme
full_name: Boissier, Jérôme
last_name: Boissier
- first_name: Céline
full_name: Cosseau, Céline
last_name: Cosseau
citation:
ama: 'Picard MAL, Vicoso B, Roquis D, et al. Dosage compensation throughout the
Schistosoma mansoni lifecycle: Specific chromatin landscape of the Z chromosome.
Genome biology and evolution. 2019;11(7):1909-1922. doi:10.1093/gbe/evz133'
apa: 'Picard, M. A. L., Vicoso, B., Roquis, D., Bulla, I., Augusto, R. C., Arancibia,
N., … Cosseau, C. (2019). Dosage compensation throughout the Schistosoma mansoni
lifecycle: Specific chromatin landscape of the Z chromosome. Genome Biology
and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evz133'
chicago: 'Picard, Marion A L, Beatriz Vicoso, David Roquis, Ingo Bulla, Ronaldo
C. Augusto, Nathalie Arancibia, Christoph Grunau, Jérôme Boissier, and Céline
Cosseau. “Dosage Compensation throughout the Schistosoma Mansoni Lifecycle: Specific
Chromatin Landscape of the Z Chromosome.” Genome Biology and Evolution.
Oxford University Press, 2019. https://doi.org/10.1093/gbe/evz133.'
ieee: 'M. A. L. Picard et al., “Dosage compensation throughout the Schistosoma
mansoni lifecycle: Specific chromatin landscape of the Z chromosome,” Genome
biology and evolution, vol. 11, no. 7. Oxford University Press, pp. 1909–1922,
2019.'
ista: 'Picard MAL, Vicoso B, Roquis D, Bulla I, Augusto RC, Arancibia N, Grunau
C, Boissier J, Cosseau C. 2019. Dosage compensation throughout the Schistosoma
mansoni lifecycle: Specific chromatin landscape of the Z chromosome. Genome biology
and evolution. 11(7), 1909–1922.'
mla: 'Picard, Marion A. L., et al. “Dosage Compensation throughout the Schistosoma
Mansoni Lifecycle: Specific Chromatin Landscape of the Z Chromosome.” Genome
Biology and Evolution, vol. 11, no. 7, Oxford University Press, 2019, pp.
1909–22, doi:10.1093/gbe/evz133.'
short: M.A.L. Picard, B. Vicoso, D. Roquis, I. Bulla, R.C. Augusto, N. Arancibia,
C. Grunau, J. Boissier, C. Cosseau, Genome Biology and Evolution 11 (2019) 1909–1922.
date_created: 2019-08-04T21:59:18Z
date_published: 2019-07-01T00:00:00Z
date_updated: 2025-05-14T11:08:50Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evz133
external_id:
isi:
- '000484039500018'
pmid:
- '31273378'
file:
- access_level: open_access
checksum: f9e8f6863a406dcc5a36b2be001c138c
content_type: application/pdf
creator: dernst
date_created: 2019-08-05T07:55:02Z
date_updated: 2020-07-14T12:47:39Z
file_id: '6765'
file_name: 2019_GenomeBiology_Picard.pdf
file_size: 580205
relation: main_file
file_date_updated: 2020-07-14T12:47:39Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1909-1922
pmid: 1
publication: Genome biology and evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Dosage compensation throughout the Schistosoma mansoni lifecycle: Specific
chromatin landscape of the Z chromosome'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2019'
...