@article{2656,
  abstract     = {Previous studies have shown that neurons in the sacral dorsal commissural nucleus (SDCN) express neurokinin-1 receptor (NK1R) and can be modulated by the co-release of GABA and glycine (Gly) from single presynaptic terminal. These results raise the possibility that GABA/Gly-cocontaining terminals might make synaptic contacts with NK1R-expressing neurons in the SDCN. In order to provide morphological evidence for this hypothesis, the triple-immunohistochemical studies were performed in the SDCN. Triple-immunofluorescence histochemical study showed that some axon terminals in close association with NK1R-immunopositive (NK1R-ip) neurons in the SDCN were immunopositive for both glutamic acid decarboxylase (GAD) and glycine transporter 2 (GlyT2). In electron microscopic dual- and triple-immunohistochemistry for GAD/GlyT2, GAD/NK1R, GlyT2/NK1R, or GAD/GlyT2/NK1R also revealed dually labeled (GAD/GlyT2-ip) synaptic terminals upon SDCN neurons, as well as GAD- and/or GlyT2-ip axon terminals in synaptic contact with NK1R-ip SDCN neurons. These results suggested that some synaptic terminals upon NK1R-expressing SDCN neurons co-released both GABA and Gly.},
  author       = {Feng, Yu and Li, Yun and Wang, Wen and Wu, Sheng and Chen, Tao and Shigemoto, Ryuichi and Mizuno, Noboru},
  issn         = {1872-7972},
  journal      = {Neuroscience Letters},
  number       = {3},
  pages        = {144 -- 148},
  publisher    = {Elsevier},
  title        = {{Morphological evidence for GABA/glycine-cocontaining terminals in synaptic contact with neurokinin-1 receptor-expressing neurons in the sacral dorsal commissural nucleus of the rat}},
  doi          = {10.1016/j.neulet.2005.06.068},
  volume       = {388},
  year         = {2005},
}

@article{2637,
  abstract     = {While the cholinergic depletion in Alzheimer's disease (AD) has been known for some time, a definitive involvement of other neurotransmitter systems has been somewhat more elusive. Our study demonstrates a clear involvement of both glutamatergic and, to a lesser extent, GABAergic neurons in an early onset transgenic mouse model of AD-like amyloid pathology. Immunohistochemical staining and subsequent quantification has revealed a statistically significant increased density of glutamatergic and GABAergic presynaptic boutons in both the plaque free and plaque adjacent cortical neuropile areas of transgenic mice as compared to non-transgenic controls. Furthermore, amyloid plaque size was shown to have a statistically significant effect on the relative area occupied by dystrophic glutamatergic neurites in the peri-plaque neuropile. These findings support our hypothesis that the amyloid pathology progresses in a time and neurotransmitter specific manner, first in the cholinergic system which appears to be most vulnerable, followed by the glutamatergic presynaptic boutons and finally the somewhat more resilient GABAergic terminals.},
  author       = {Bell, Karen and De Kort, G J and Steggerda, S and Shigemoto, Ryuichi and Ribeiro Da Silva, Alfredo and Cuello, Augusto},
  issn         = {1872-7972},
  journal      = {Neuroscience Letters},
  number       = {2},
  pages        = {143 -- 147},
  publisher    = {Elsevier},
  title        = {{Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology}},
  doi          = {10.1016/j.neulet.2003.09.027},
  volume       = {353},
  year         = {2003},
}

@article{2523,
  abstract     = {Injection of large amounts of a mixture of horseradish peroxidase and wheat germ agglutinin-horseradish peroxidase conjugate into the upper cervical segments of the spinal cord in the Japanese monkey (Macaca fuscata) led to the retrograde labeling of a small number of neuronal cell bodies within the rostral part of the subthalamic nucleus of Luys. Direct projection from the subthalamic nucleus to the spinal cord appeared to be much less prominent in the Japanese monkey than in the cat and rat.},
  author       = {Mizuno, Noboru and Ueyama, Teizo and Itoh, Kazuo and Satoda, Takahiro and Tashiro, Takashi and Shigemoto, Ryuichi},
  issn         = {1872-7972},
  journal      = {Neuroscience Letters},
  number       = {1},
  pages        = {13 -- 18},
  publisher    = {Elsevier},
  title        = {{Direct projections from the subthalamic nucleus of Luys to the spinal cord in the Japanese monkey}},
  doi          = {10.1016/0304-3940(88)90473-9},
  volume       = {89},
  year         = {1988},
}