---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21716'
abstract:
- lang: eng
  text: Male germline development in plants is highly sensitive to heat stress, with
    elevated temperatures frequently impairing male fertility and consequently reducing
    seed production. Indeed, recent global warming has decreased major crop yields,
    emphasizing the urgent need to elucidate the molecular and cellular mechanisms
    underlying heat-induced male sterility. This review synthesizes current knowledge
    on how heat stress disrupts microsporogenesis and microgametogenesis, and how
    plants counteract these stresses through diverse thermotolerance mechanisms. We
    emphasize temperature-sensitive processes, including meiotic progression in male
    germ cells, programmed cell death of somatic tapetal nurse cells, and post-meiotic
    pollen tube development. We further discuss how epigenetic regulators enhance
    thermotolerance by reprogramming DNA methylation landscapes and modulating histone
    variant distribution. Finally, we propose future directions aimed at understanding
    the mechanisms of reproductive thermotolerance from the epigenetic perspective.
acknowledgement: This work was supported by JSPS KAKENHI (grant number JP22J01430)
  and the Osamu Hayaishi Memorial Scholarship for Study Abroad for H.N.
article_number: '102881'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Hiroki
  full_name: Nagai, Hiroki
  id: 608df3e6-e2ab-11ed-8890-c9318cec7da4
  last_name: Nagai
  orcid: 0000-0003-1671-9434
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
citation:
  ama: NAGAI H, Feng X. Genetic and epigenetic mechanisms underlying male reproductive
    thermotolerance. <i>Current Opinion in Plant Biology</i>. 2026;91(6). doi:<a href="https://doi.org/10.1016/j.pbi.2026.102881">10.1016/j.pbi.2026.102881</a>
  apa: NAGAI, H., &#38; Feng, X. (2026). Genetic and epigenetic mechanisms underlying
    male reproductive thermotolerance. <i>Current Opinion in Plant Biology</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.pbi.2026.102881">https://doi.org/10.1016/j.pbi.2026.102881</a>
  chicago: NAGAI, HIROKI, and Xiaoqi Feng. “Genetic and Epigenetic Mechanisms Underlying
    Male Reproductive Thermotolerance.” <i>Current Opinion in Plant Biology</i>. Elsevier,
    2026. <a href="https://doi.org/10.1016/j.pbi.2026.102881">https://doi.org/10.1016/j.pbi.2026.102881</a>.
  ieee: H. NAGAI and X. Feng, “Genetic and epigenetic mechanisms underlying male reproductive
    thermotolerance,” <i>Current Opinion in Plant Biology</i>, vol. 91, no. 6. Elsevier,
    2026.
  ista: NAGAI H, Feng X. 2026. Genetic and epigenetic mechanisms underlying male reproductive
    thermotolerance. Current Opinion in Plant Biology. 91(6), 102881.
  mla: NAGAI, HIROKI, and Xiaoqi Feng. “Genetic and Epigenetic Mechanisms Underlying
    Male Reproductive Thermotolerance.” <i>Current Opinion in Plant Biology</i>, vol.
    91, no. 6, 102881, Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.pbi.2026.102881">10.1016/j.pbi.2026.102881</a>.
  short: H. NAGAI, X. Feng, Current Opinion in Plant Biology 91 (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: No data was used for the research described in the article.
date_created: 2026-04-12T22:01:50Z
date_published: 2026-06-01T00:00:00Z
date_updated: 2026-07-27T12:26:03Z
day: '01'
ddc:
- '580'
department:
- _id: XiFe
doi: 10.1016/j.pbi.2026.102881
external_id:
  pmid:
  - '41955759'
file:
- access_level: open_access
  checksum: 929e801eb8f2aef08cf9d9f97be2b2af
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  creator: dernst
  date_created: 2026-07-27T12:20:55Z
  date_updated: 2026-07-27T12:20:55Z
  file_id: '22428'
  file_name: 2026_CurrentOpinionPlantBiology_Nagai.pdf
  file_size: 2255022
  relation: main_file
  success: 1
file_date_updated: 2026-07-27T12:20:55Z
has_accepted_license: '1'
intvolume: '        91'
issue: '6'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: Current Opinion in Plant Biology
publication_identifier:
  eissn:
  - 1879-0356
  issn:
  - 1369-5266
publication_status: published
publisher: Elsevier
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Genetic and epigenetic mechanisms underlying male reproductive thermotolerance
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2026'
...
---
_id: '7142'
abstract:
- lang: eng
  text: The phytohormone auxin acts as an amazingly versatile coordinator of plant
    growth and development. With its morphogen-like properties, auxin controls sites
    and timing of differentiation and/or growth responses both, in quantitative and
    qualitative terms. Specificity in the auxin response depends largely on distinct
    modes of signal transmission, by which individual cells perceive and convert auxin
    signals into a remarkable diversity of responses. The best understood, or so-called
    canonical mechanism of auxin perception ultimately results in variable adjustments
    of the cellular transcriptome, via a short, nuclear signal transduction pathway.
    Additional findings that accumulated over decades implied that an additional,
    presumably, cell surface-based auxin perception mechanism mediates very rapid
    cellular responses and decisively contributes to the cell's overall hormonal response.
    Recent investigations into both, nuclear and cell surface auxin signalling challenged
    this assumed partition of roles for different auxin signalling pathways and revealed
    an unexpected complexity in transcriptional and non-transcriptional cellular responses
    mediated by auxin.
acknowledgement: Research in J.F. laboratory is funded by the European Union's Horizon
  2020 program (ERC grant agreement n° 742985); C.L. is supported by the Austrian
  Science Fund (FWF grant P 31493).
article_processing_charge: No
article_type: original
author:
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
- first_name: Christian
  full_name: Luschnig, Christian
  last_name: Luschnig
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: 'Gallei MC, Luschnig C, Friml J. Auxin signalling in growth: Schrödinger’s
    cat out of the bag. <i>Current Opinion in Plant Biology</i>. 2020;53(2):43-49.
    doi:<a href="https://doi.org/10.1016/j.pbi.2019.10.003">10.1016/j.pbi.2019.10.003</a>'
  apa: 'Gallei, M. C., Luschnig, C., &#38; Friml, J. (2020). Auxin signalling in growth:
    Schrödinger’s cat out of the bag. <i>Current Opinion in Plant Biology</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.pbi.2019.10.003">https://doi.org/10.1016/j.pbi.2019.10.003</a>'
  chicago: 'Gallei, Michelle C, Christian Luschnig, and Jiří Friml. “Auxin Signalling
    in Growth: Schrödinger’s Cat out of the Bag.” <i>Current Opinion in Plant Biology</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.pbi.2019.10.003">https://doi.org/10.1016/j.pbi.2019.10.003</a>.'
  ieee: 'M. C. Gallei, C. Luschnig, and J. Friml, “Auxin signalling in growth: Schrödinger’s
    cat out of the bag,” <i>Current Opinion in Plant Biology</i>, vol. 53, no. 2.
    Elsevier, pp. 43–49, 2020.'
  ista: 'Gallei MC, Luschnig C, Friml J. 2020. Auxin signalling in growth: Schrödinger’s
    cat out of the bag. Current Opinion in Plant Biology. 53(2), 43–49.'
  mla: 'Gallei, Michelle C., et al. “Auxin Signalling in Growth: Schrödinger’s Cat
    out of the Bag.” <i>Current Opinion in Plant Biology</i>, vol. 53, no. 2, Elsevier,
    2020, pp. 43–49, doi:<a href="https://doi.org/10.1016/j.pbi.2019.10.003">10.1016/j.pbi.2019.10.003</a>.'
  short: M.C. Gallei, C. Luschnig, J. Friml, Current Opinion in Plant Biology 53 (2020)
    43–49.
corr_author: '1'
date_created: 2019-12-02T12:05:26Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2026-04-07T14:18:57Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.pbi.2019.10.003
ec_funded: 1
external_id:
  isi:
  - '000521120600007'
  pmid:
  - '31760231'
intvolume: '        53'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 43-49
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Current Opinion in Plant Biology
publication_identifier:
  eissn:
  - 1879-0356
  issn:
  - 1369-5266
publication_status: published
publisher: Elsevier
quality_controlled: '1'
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scopus_import: '1'
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title: 'Auxin signalling in growth: Schrödinger''s cat out of the bag'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 53
year: '2020'
...