[{"day":"01","department":[{"_id":"PreCl"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa":1,"title":"Critical loss of primary implant stability in osteosynthesis locking screws under cyclic overloading","article_processing_charge":"Yes (in subscription journal)","publication_identifier":{"eissn":["1873-4030"],"issn":["1350-4533"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"isi":1,"file":[{"access_level":"open_access","relation":"main_file","creator":"dernst","content_type":"application/pdf","date_created":"2024-03-25T08:29:52Z","file_size":10039402,"date_updated":"2024-03-25T08:29:52Z","file_id":"15177","file_name":"2024_MedEngineeringPhysics_SilvaHenao.pdf","success":1,"checksum":"974acbf2731e7382dcf5920ac762e551"}],"doi":"10.1016/j.medengphy.2024.104143","acknowledgement":"The authors declare no conflict of interest related to this study. This project was funded by the Gesellschaft fuer Forschungsfoerderung Niederoesterreich m.b.H. Life Science Call 2017 Grant No. LS17004 and Science call 2019 Dissertationen Grant No. SC19014. No ethical approval was required for this study.","publisher":"Elsevier","date_published":"2024-04-01T00:00:00Z","_id":"15164","quality_controlled":"1","article_number":"104143","volume":126,"month":"04","year":"2024","publication_status":"published","file_date_updated":"2024-03-25T08:29:52Z","pmid":1,"author":[{"last_name":"Silva-Henao","first_name":"Juan D.","full_name":"Silva-Henao, Juan D."},{"id":"80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8","full_name":"Schober, Sophie","last_name":"Schober","first_name":"Sophie"},{"full_name":"Pahr, Dieter H.","last_name":"Pahr","first_name":"Dieter H."},{"full_name":"Reisinger, Andreas G.","first_name":"Andreas G.","last_name":"Reisinger"}],"intvolume":"       126","date_updated":"2025-09-04T13:11:03Z","ddc":["610"],"citation":{"short":"J.D. Silva-Henao, S. Schober, D.H. Pahr, A.G. Reisinger, Medical Engineering and Physics 126 (2024).","mla":"Silva-Henao, Juan D., et al. “Critical Loss of Primary Implant Stability in Osteosynthesis Locking Screws under Cyclic Overloading.” <i>Medical Engineering and Physics</i>, vol. 126, 104143, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.medengphy.2024.104143\">10.1016/j.medengphy.2024.104143</a>.","ieee":"J. D. Silva-Henao, S. Schober, D. H. Pahr, and A. G. Reisinger, “Critical loss of primary implant stability in osteosynthesis locking screws under cyclic overloading,” <i>Medical Engineering and Physics</i>, vol. 126. Elsevier, 2024.","ama":"Silva-Henao JD, Schober S, Pahr DH, Reisinger AG. Critical loss of primary implant stability in osteosynthesis locking screws under cyclic overloading. <i>Medical Engineering and Physics</i>. 2024;126. doi:<a href=\"https://doi.org/10.1016/j.medengphy.2024.104143\">10.1016/j.medengphy.2024.104143</a>","ista":"Silva-Henao JD, Schober S, Pahr DH, Reisinger AG. 2024. Critical loss of primary implant stability in osteosynthesis locking screws under cyclic overloading. Medical Engineering and Physics. 126, 104143.","apa":"Silva-Henao, J. D., Schober, S., Pahr, D. H., &#38; Reisinger, A. G. (2024). Critical loss of primary implant stability in osteosynthesis locking screws under cyclic overloading. <i>Medical Engineering and Physics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.medengphy.2024.104143\">https://doi.org/10.1016/j.medengphy.2024.104143</a>","chicago":"Silva-Henao, Juan D., Sophie Schober, Dieter H. Pahr, and Andreas G. Reisinger. “Critical Loss of Primary Implant Stability in Osteosynthesis Locking Screws under Cyclic Overloading.” <i>Medical Engineering and Physics</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.medengphy.2024.104143\">https://doi.org/10.1016/j.medengphy.2024.104143</a>."},"article_type":"original","language":[{"iso":"eng"}],"date_created":"2024-03-24T23:00:58Z","scopus_import":"1","publication":"Medical Engineering and Physics","oa_version":"Published Version","type":"journal_article","abstract":[{"text":"Primary implant stability, which refers to the stability of the implant during the initial healing period is a crucial factor in determining the long-term success of the implant and lays the foundation for secondary implant stability achieved through osseointegration. Factors affecting primary stability include implant design, surgical technique, and patient-specific factors like bone quality and morphology. In vivo, the cyclic nature of anatomical loading puts osteosynthesis locking screws under dynamic loads, which can lead to the formation of micro cracks and defects that slowly degrade the mechanical connection between the bone and screw, thus compromising the initial stability and secondary stability of the implant. Monotonic quasi-static loading used for testing the holding capacity of implanted screws is not well suited to capture this behavior since it cannot capture the progressive deterioration of peri‑implant bone at small displacements. In order to address this issue, this study aims to determine a critical point of loss of primary implant stability in osteosynthesis locking screws under cyclic overloading by investigating the evolution of damage, dissipated energy, and permanent deformation. A custom-made test setup was used to test implanted 2.5 mm locking screws under cyclic overloading test. For each loading cycle, maximum forces and displacement were recorded as well as initial and final cycle displacements and used to calculate damage and energy dissipation evolution. The results of this study demonstrate that for axial, shear, and mixed loading significant damage and energy dissipation can be observed at approximately 20 % of the failure force. Additionally, at this load level, permanent deformations on the screw-bone interface were found to be in the range of 50 to 150 mm which promotes osseointegration and secondary implant stability. This research can assist surgeons in making informed preoperative decisions by providing a better understanding of the critical point of loss of primary implant stability, thus improving the long-term success of the implant and overall patient satisfaction.","lang":"eng"}],"external_id":{"pmid":["38621845"],"isi":["001219145400001"]},"has_accepted_license":"1","status":"public"},{"publication_identifier":{"eissn":["1944-8007"],"issn":["0094-8276"]},"tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"article_processing_charge":"Yes","APC_amount":"1470 EUR","department":[{"_id":"CaMu"}],"day":"16","oa":1,"title":"A pre-monsoon signal of false alarms of Indian monsoon droughts","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_number":"e2023GL106569","quality_controlled":"1","_id":"15165","date_published":"2024-03-16T00:00:00Z","publisher":"Wiley","acknowledgement":"The author gratefully acknowledges ISTA for supporting this research through funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Project CLUSTER, grant agreement No. 805041).","isi":1,"doi":"10.1029/2023GL106569","file":[{"file_size":2887134,"success":1,"checksum":"243bd966aca968ec7d9e474af8639f8d","file_name":"2024_GeophysResLetters_Goswami.pdf","file_id":"15178","date_updated":"2024-03-25T08:36:00Z","creator":"dernst","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2024-03-25T08:36:00Z"}],"author":[{"full_name":"Goswami, Bidyut B","id":"3a4ac09c-6d61-11ec-bf66-884cde66b64b","last_name":"Goswami","orcid":"0000-0001-8602-3083","first_name":"Bidyut B"}],"month":"03","issue":"5","volume":51,"file_date_updated":"2024-03-25T08:36:00Z","publication_status":"published","year":"2024","citation":{"chicago":"GOSWAMI, BIDYUT B. “A Pre-Monsoon Signal of False Alarms of Indian Monsoon Droughts.” <i>Geophysical Research Letters</i>. Wiley, 2024. <a href=\"https://doi.org/10.1029/2023GL106569\">https://doi.org/10.1029/2023GL106569</a>.","mla":"GOSWAMI, BIDYUT B. “A Pre-Monsoon Signal of False Alarms of Indian Monsoon Droughts.” <i>Geophysical Research Letters</i>, vol. 51, no. 5, e2023GL106569, Wiley, 2024, doi:<a href=\"https://doi.org/10.1029/2023GL106569\">10.1029/2023GL106569</a>.","short":"B.B. GOSWAMI, Geophysical Research Letters 51 (2024).","apa":"GOSWAMI, B. B. (2024). A pre-monsoon signal of false alarms of Indian monsoon droughts. <i>Geophysical Research Letters</i>. Wiley. <a href=\"https://doi.org/10.1029/2023GL106569\">https://doi.org/10.1029/2023GL106569</a>","ama":"GOSWAMI BB. A pre-monsoon signal of false alarms of Indian monsoon droughts. <i>Geophysical Research Letters</i>. 2024;51(5). doi:<a href=\"https://doi.org/10.1029/2023GL106569\">10.1029/2023GL106569</a>","ista":"GOSWAMI BB. 2024. A pre-monsoon signal of false alarms of Indian monsoon droughts. Geophysical Research Letters. 51(5), e2023GL106569.","ieee":"B. B. GOSWAMI, “A pre-monsoon signal of false alarms of Indian monsoon droughts,” <i>Geophysical Research Letters</i>, vol. 51, no. 5. Wiley, 2024."},"article_type":"original","DOAJ_listed":"1","ec_funded":1,"language":[{"iso":"eng"}],"abstract":[{"text":"Current knowledge suggests a drought Indian monsoon (perhaps a severe one) when the El Nino Southern Oscillation and Pacific Decadal Oscillation each exhibit positive phases (a joint positive phase). For the monsoons, which are exceptions in this regard, we found northeast India often gets excess pre-monsoon rainfall. Further investigation reveals that this excess pre-monsoon rainfall is produced by the interaction of the large-scale circulation associated with the joint phase with the mountains in northeast India. We posit that a warmer troposphere, a consequence of excess rainfall over northeast India, drives a stronger monsoon circulation and enhances monsoon rainfall over central India. Hence, we argue that pre-monsoon rainfall over northeast India can be used for seasonal monsoon rainfall prediction over central India. Most importantly, its predictive value is at its peak when the Pacific Ocean exhibits a joint positive phase and the threat of extreme drought monsoon looms over India.","lang":"eng"}],"status":"public","has_accepted_license":"1","external_id":{"isi":["001181635700001"]},"scopus_import":"1","oa_version":"Published Version","publication":"Geophysical Research Letters","date_created":"2024-03-24T23:00:58Z","corr_author":"1","type":"journal_article","OA_type":"gold","project":[{"grant_number":"805041","call_identifier":"H2020","_id":"629205d8-2b32-11ec-9570-e1356ff73576","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate"}],"date_updated":"2025-09-04T13:11:41Z","ddc":["550"],"intvolume":"        51","OA_place":"publisher"},{"project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"intvolume":"       383","date_updated":"2025-09-04T13:12:19Z","language":[{"iso":"eng"}],"citation":{"short":"N. Jakhar, M. Ibáñez, Science 383 (2024) 1184.","mla":"Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” <i>Science</i>, vol. 383, no. 6688, American Association for the Advancement of Science, 2024, p. 1184, doi:<a href=\"https://doi.org/10.1126/science.ado4077\">10.1126/science.ado4077</a>.","ama":"Jakhar N, Ibáñez M. Electron highways are cooler. <i>Science</i>. 2024;383(6688):1184. doi:<a href=\"https://doi.org/10.1126/science.ado4077\">10.1126/science.ado4077</a>","ista":"Jakhar N, Ibáñez M. 2024. Electron highways are cooler. Science. 383(6688), 1184.","ieee":"N. Jakhar and M. Ibáñez, “Electron highways are cooler,” <i>Science</i>, vol. 383, no. 6688. American Association for the Advancement of Science, p. 1184, 2024.","apa":"Jakhar, N., &#38; Ibáñez, M. (2024). Electron highways are cooler. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.ado4077\">https://doi.org/10.1126/science.ado4077</a>","chicago":"Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” <i>Science</i>. American Association for the Advancement of Science, 2024. <a href=\"https://doi.org/10.1126/science.ado4077\">https://doi.org/10.1126/science.ado4077</a>."},"article_type":"letter_note","type":"journal_article","corr_author":"1","publication":"Science","date_created":"2024-03-24T23:00:58Z","oa_version":"None","scopus_import":"1","status":"public","external_id":{"isi":["001273082800019"],"pmid":["38484066"]},"abstract":[{"text":"Reducing defects boosts room-temperature performance of a thermoelectric device","lang":"eng"}],"volume":383,"issue":"6688","month":"03","year":"2024","publication_status":"published","pmid":1,"page":"1184","author":[{"last_name":"Navita","first_name":"Navita","orcid":"0000-0001-7408-8197","id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4","full_name":"Navita, Navita"},{"last_name":"Ibáñez","first_name":"Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria"}],"acknowledgement":"The authors thank the Werner-Siemens-Stiftung and the Institute of Science and Technology Austria for financial support.","isi":1,"doi":"10.1126/science.ado4077","publisher":"American Association for the Advancement of Science","_id":"15166","date_published":"2024-03-14T00:00:00Z","quality_controlled":"1","day":"14","department":[{"_id":"MaIb"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Electron highways are cooler","article_processing_charge":"No","publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]}},{"publication_status":"published","year":"2024","month":"03","issue":"3","volume":109,"author":[{"last_name":"Al Hyder","first_name":"Ragheed","full_name":"Al Hyder, Ragheed","id":"d1c405be-ae15-11ed-8510-ccf53278162e"},{"full_name":"Chevy, F.","first_name":"F.","last_name":"Chevy"},{"full_name":"Leyronas, X.","last_name":"Leyronas","first_name":"X."}],"date_updated":"2025-09-04T13:07:33Z","arxiv":1,"intvolume":"       109","abstract":[{"lang":"eng","text":"We perform a diagrammatic analysis of the energy of a mobile impurity immersed in a strongly interacting two-component Fermi gas to second order in the impurity-bath interaction. These corrections demonstrate divergent behavior in the limit of large impurity momentum. We show the fundamental processes responsible for these logarithmically divergent terms. We study the problem in the general case without any assumptions regarding the fermion-fermion interactions in the bath. We show that the divergent term can be summed up to all orders in the Fermi-Fermi interaction and that the resulting expression is equivalent to the one obtained in the few-body calculation. Finally, we provide a perturbative calculation to the second order in the Fermi-Fermi interaction, and we show the diagrams responsible for these terms."}],"status":"public","external_id":{"isi":["001198511300017"],"arxiv":["2311.14536"]},"oa_version":"Preprint","scopus_import":"1","date_created":"2024-03-24T23:00:59Z","publication":"Physical Review A","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2311.14536"}],"type":"journal_article","corr_author":"1","article_type":"original","citation":{"chicago":"Al Hyder, Ragheed, F. Chevy, and X. Leyronas. “Exploring Beyond-Mean-Field Logarithmic Divergences in Fermi-Polaron Energy.” <i>Physical Review A</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">https://doi.org/10.1103/PhysRevA.109.033315</a>.","mla":"Al Hyder, Ragheed, et al. “Exploring Beyond-Mean-Field Logarithmic Divergences in Fermi-Polaron Energy.” <i>Physical Review A</i>, vol. 109, no. 3, 033315, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">10.1103/PhysRevA.109.033315</a>.","short":"R. Al Hyder, F. Chevy, X. Leyronas, Physical Review A 109 (2024).","apa":"Al Hyder, R., Chevy, F., &#38; Leyronas, X. (2024). Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy. <i>Physical Review A</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">https://doi.org/10.1103/PhysRevA.109.033315</a>","ieee":"R. Al Hyder, F. Chevy, and X. Leyronas, “Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy,” <i>Physical Review A</i>, vol. 109, no. 3. American Physical Society, 2024.","ista":"Al Hyder R, Chevy F, Leyronas X. 2024. Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy. Physical Review A. 109(3), 033315.","ama":"Al Hyder R, Chevy F, Leyronas X. Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy. <i>Physical Review A</i>. 2024;109(3). doi:<a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">10.1103/PhysRevA.109.033315</a>"},"language":[{"iso":"eng"}],"oa":1,"title":"Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"MiLe"}],"day":"19","publication_identifier":{"issn":["2469-9926"],"eissn":["2469-9934"]},"article_processing_charge":"No","publisher":"American Physical Society","acknowledgement":"We thank Félix Werner and Kris Van Houcke for interesting discussions.","doi":"10.1103/PhysRevA.109.033315","isi":1,"article_number":"033315","_id":"15167","quality_controlled":"1","date_published":"2024-03-19T00:00:00Z"},{"intvolume":"       964","date_updated":"2025-09-04T13:09:41Z","arxiv":1,"ddc":["550"],"publication":"Astrophysical Journal","date_created":"2024-03-24T23:00:59Z","oa_version":"Published Version","scopus_import":"1","type":"journal_article","abstract":[{"text":"The James Webb Space Telescope is revealing a new population of dust-reddened broad-line active galactic nuclei (AGN) at redshifts z ≳ 5. Here we present deep NIRSpec/Prism spectroscopy from the Cycle 1 Treasury program Ultradeep NIRSpec and NIRCam ObserVations before the Epoch of Reionization (UNCOVER) of 15 AGN candidates selected to be compact, with red continua in the rest-frame optical but with blue slopes in the UV. From NIRCam photometry alone, they could have been dominated by dusty star formation or an AGN. Here we show that the majority of the compact red sources in UNCOVER are dust-reddened AGN: 60% show definitive evidence for broad-line Hα with a FWHM > 2000 km s −1, 20% of the current data are inconclusive, and 20% are brown dwarf stars. We propose an updated photometric criterion to select red z > 5 AGN that excludes brown dwarfs and is expected to yield >80% AGN. Remarkably, among all zphot > 5 galaxies with F277W – F444W > 1 in UNCOVER at least 33% are AGN regardless of compactness, climbing to at least 80% AGN for sources with F277W – F444W > 1.6. The confirmed AGN have black hole masses of 107–109M⊙. While their UV luminosities (−16 > MUV > −20 AB mag) are low compared to UV-selected AGN at these epochs, consistent with percent-level scattered AGN light or low levels of unobscured star formation, the inferred bolometric luminosities are typical of 107–109M⊙ black holes radiating at ∼10%–40% the Eddington limit. The number densities are surprisingly high at ∼10−5 Mpc−3 mag−1, 100 times more common than the faintest UV-selected quasars, while accounting for ∼1% of the UV-selected galaxies. While their UV faintness suggests they may not contribute strongly to reionization, their ubiquity poses challenges to models of black hole growth.","lang":"eng"}],"status":"public","external_id":{"arxiv":["2309.05714"],"isi":["001184746500001"]},"has_accepted_license":"1","citation":{"chicago":"Greene, Jenny E., Ivo Labbe, Andy D. Goulding, Lukas J. Furtak, Iryna Chemerynska, Vasily Kokorev, Pratika Dayal, et al. “UNCOVER Spectroscopy Confirms the Surprising Ubiquity of Active Galactic Nuclei in Red Sources at z &#62; 5.” <i>Astrophysical Journal</i>. IOP Publishing, 2024. <a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">https://doi.org/10.3847/1538-4357/ad1e5f</a>.","ista":"Greene JE, Labbe I, Goulding AD, Furtak LJ, Chemerynska I, Kokorev V, Dayal P, Volonteri M, Williams CC, Wang B, Setton DJ, Burgasser AJ, Bezanson R, Atek H, Brammer G, Cutler SE, Feldmann R, Fujimoto S, Glazebrook K, De Graaff A, Khullar G, Leja J, Marchesini D, Maseda MV, Matthee JJ, Miller TB, Naidu RP, Nanayakkara T, Oesch PA, Pan R, Papovich C, Price SH, Van Dokkum P, Weaver JR, Whitaker KE, Zitrin A. 2024. UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5. Astrophysical Journal. 964, 39.","ama":"Greene JE, Labbe I, Goulding AD, et al. UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5. <i>Astrophysical Journal</i>. 2024;964. doi:<a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">10.3847/1538-4357/ad1e5f</a>","ieee":"J. E. Greene <i>et al.</i>, “UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5,” <i>Astrophysical Journal</i>, vol. 964. IOP Publishing, 2024.","apa":"Greene, J. E., Labbe, I., Goulding, A. D., Furtak, L. J., Chemerynska, I., Kokorev, V., … Zitrin, A. (2024). UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5. <i>Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">https://doi.org/10.3847/1538-4357/ad1e5f</a>","short":"J.E. Greene, I. Labbe, A.D. Goulding, L.J. Furtak, I. Chemerynska, V. Kokorev, P. Dayal, M. Volonteri, C.C. Williams, B. Wang, D.J. Setton, A.J. Burgasser, R. Bezanson, H. Atek, G. Brammer, S.E. Cutler, R. Feldmann, S. Fujimoto, K. Glazebrook, A. De Graaff, G. Khullar, J. Leja, D. Marchesini, M.V. Maseda, J.J. Matthee, T.B. Miller, R.P. Naidu, T. Nanayakkara, P.A. Oesch, R. Pan, C. Papovich, S.H. Price, P. Van Dokkum, J.R. Weaver, K.E. Whitaker, A. Zitrin, Astrophysical Journal 964 (2024).","mla":"Greene, Jenny E., et al. “UNCOVER Spectroscopy Confirms the Surprising Ubiquity of Active Galactic Nuclei in Red Sources at z &#62; 5.” <i>Astrophysical Journal</i>, vol. 964, 39, IOP Publishing, 2024, doi:<a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">10.3847/1538-4357/ad1e5f</a>."},"article_type":"original","DOAJ_listed":"1","language":[{"iso":"eng"}],"year":"2024","file_date_updated":"2024-03-25T08:02:43Z","publication_status":"published","volume":964,"month":"03","author":[{"last_name":"Greene","first_name":"Jenny E.","full_name":"Greene, Jenny E."},{"last_name":"Labbe","first_name":"Ivo","full_name":"Labbe, Ivo"},{"full_name":"Goulding, Andy D.","last_name":"Goulding","first_name":"Andy D."},{"last_name":"Furtak","first_name":"Lukas J.","full_name":"Furtak, Lukas J."},{"full_name":"Chemerynska, Iryna","first_name":"Iryna","last_name":"Chemerynska"},{"full_name":"Kokorev, Vasily","first_name":"Vasily","last_name":"Kokorev"},{"full_name":"Dayal, Pratika","first_name":"Pratika","last_name":"Dayal"},{"first_name":"Marta","last_name":"Volonteri","full_name":"Volonteri, Marta"},{"full_name":"Williams, Christina C.","last_name":"Williams","first_name":"Christina C."},{"full_name":"Wang, Bingjie","last_name":"Wang","first_name":"Bingjie"},{"first_name":"David J.","last_name":"Setton","full_name":"Setton, David J."},{"first_name":"Adam J.","last_name":"Burgasser","full_name":"Burgasser, Adam J."},{"full_name":"Bezanson, Rachel","last_name":"Bezanson","first_name":"Rachel"},{"full_name":"Atek, Hakim","first_name":"Hakim","last_name":"Atek"},{"full_name":"Brammer, Gabriel","last_name":"Brammer","first_name":"Gabriel"},{"full_name":"Cutler, Sam E.","last_name":"Cutler","first_name":"Sam E."},{"last_name":"Feldmann","first_name":"Robert","full_name":"Feldmann, Robert"},{"first_name":"Seiji","last_name":"Fujimoto","full_name":"Fujimoto, Seiji"},{"full_name":"Glazebrook, Karl","last_name":"Glazebrook","first_name":"Karl"},{"full_name":"De Graaff, Anna","last_name":"De Graaff","first_name":"Anna"},{"full_name":"Khullar, Gourav","first_name":"Gourav","last_name":"Khullar"},{"full_name":"Leja, Joel","first_name":"Joel","last_name":"Leja"},{"full_name":"Marchesini, Danilo","last_name":"Marchesini","first_name":"Danilo"},{"full_name":"Maseda, Michael V.","last_name":"Maseda","first_name":"Michael V."},{"id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","first_name":"Jorryt J","orcid":"0000-0003-2871-127X","last_name":"Matthee"},{"full_name":"Miller, Tim B.","first_name":"Tim B.","last_name":"Miller"},{"last_name":"Naidu","first_name":"Rohan P.","full_name":"Naidu, Rohan P."},{"last_name":"Nanayakkara","first_name":"Themiya","full_name":"Nanayakkara, Themiya"},{"full_name":"Oesch, Pascal A.","last_name":"Oesch","first_name":"Pascal A."},{"last_name":"Pan","first_name":"Richard","full_name":"Pan, Richard"},{"first_name":"Casey","last_name":"Papovich","full_name":"Papovich, Casey"},{"last_name":"Price","first_name":"Sedona H.","full_name":"Price, Sedona H."},{"full_name":"Van Dokkum, Pieter","first_name":"Pieter","last_name":"Van Dokkum"},{"last_name":"Weaver","first_name":"John R.","full_name":"Weaver, John R."},{"full_name":"Whitaker, Katherine E.","first_name":"Katherine E.","last_name":"Whitaker"},{"full_name":"Zitrin, Adi","last_name":"Zitrin","first_name":"Adi"}],"isi":1,"doi":"10.3847/1538-4357/ad1e5f","acknowledgement":"J.E.G. and A.D.G acknowledge support from NSF/AAG grant No. 1007094, and J.E.G. also acknowledges support from NSF/AAG grant No. 1007052. A.Z. acknowledges support by grant No. 2020750 from the United States-Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Ministry of Science & Technology of Israel. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant No. 140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. P.D. acknowledges support from the NWO grant 016.VIDI.189.162 (\"ODIN\") and from the European Commission's and University of Groningen's CO-FUND Rosalind Franklin program. K.G. and T.N. acknowledge support from Australian Research Council Laureate Fellowship FL180100060. H.A. and I.C. acknowledge support from CNES, focused on the JWST mission, and the Programme National Cosmology and Galaxies (PNCG) of CNRS/INSU with INP and IN2P3, cofunded by CEA and CNES. R.P.N. acknowledges funding from JWST programs GO-1933 and GO-2279. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. The research of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation. B.W. acknowledges support from JWST-GO-02561.022-A. A.J.B. acknowledges funding support from NASA/ADAP grant 21-ADAP21-0187. Support for this work was provided by The Brinson Foundation through a Brinson Prize Fellowship grant. R.P.N. acknowledges support for this work provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. C.P. thanks Marsha and Ralph Schilling for the generous support of this research.","file":[{"file_size":2700137,"date_updated":"2024-03-25T08:02:43Z","file_name":"2024_AstrophysicalJourn_Greene.pdf","file_id":"15176","checksum":"389a880e176799d5c062ea7cb82d08c9","success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","content_type":"application/pdf","date_created":"2024-03-25T08:02:43Z"}],"publisher":"IOP Publishing","date_published":"2024-03-01T00:00:00Z","_id":"15170","quality_controlled":"1","article_number":"39","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa":1,"title":"UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z > 5","day":"01","department":[{"_id":"JoMa"}],"article_processing_charge":"Yes","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"article_type":"original","citation":{"chicago":"Agnes, Everton J., and Tim P Vogels. “Co-Dependent Excitatory and Inhibitory Plasticity Accounts for Quick, Stable and Long-Lasting Memories in Biological Networks.” <i>Nature Neuroscience</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41593-024-01597-4\">https://doi.org/10.1038/s41593-024-01597-4</a>.","mla":"Agnes, Everton J., and Tim P. Vogels. “Co-Dependent Excitatory and Inhibitory Plasticity Accounts for Quick, Stable and Long-Lasting Memories in Biological Networks.” <i>Nature Neuroscience</i>, vol. 27, Springer Nature, 2024, pp. 964–74, doi:<a href=\"https://doi.org/10.1038/s41593-024-01597-4\">10.1038/s41593-024-01597-4</a>.","short":"E.J. Agnes, T.P. Vogels, Nature Neuroscience 27 (2024) 964–974.","apa":"Agnes, E. J., &#38; Vogels, T. P. (2024). Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks. <i>Nature Neuroscience</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41593-024-01597-4\">https://doi.org/10.1038/s41593-024-01597-4</a>","ista":"Agnes EJ, Vogels TP. 2024. Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks. Nature Neuroscience. 27, 964–974.","ama":"Agnes EJ, Vogels TP. Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks. <i>Nature Neuroscience</i>. 2024;27:964-974. doi:<a href=\"https://doi.org/10.1038/s41593-024-01597-4\">10.1038/s41593-024-01597-4</a>","ieee":"E. J. Agnes and T. P. Vogels, “Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks,” <i>Nature Neuroscience</i>, vol. 27. Springer Nature, pp. 964–974, 2024."},"ec_funded":1,"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"The brain’s functionality is developed and maintained through synaptic plasticity. As synapses undergo plasticity, they also affect each other. The nature of such ‘co-dependency’ is difficult to disentangle experimentally, because multiple synapses must be monitored simultaneously. To help understand the experimentally observed phenomena, we introduce a framework that formalizes synaptic co-dependency between different connection types. The resulting model explains how inhibition can gate excitatory plasticity while neighboring excitatory–excitatory interactions determine the strength of long-term potentiation. Furthermore, we show how the interplay between excitatory and inhibitory synapses can account for the quick rise and long-term stability of a variety of synaptic weight profiles, such as orientation tuning and dendritic clustering of co-active synapses. In recurrent neuronal networks, co-dependent plasticity produces rich and stable motor cortex-like dynamics with high input sensitivity. Our results suggest an essential role for the neighborly synaptic interaction during learning, connecting micro-level physiology with network-wide phenomena."}],"status":"public","external_id":{"isi":["001190081400001"],"pmid":["38509348 "]},"has_accepted_license":"1","scopus_import":"1","oa_version":"Published Version","date_created":"2024-03-24T23:01:00Z","publication":"Nature Neuroscience","type":"journal_article","project":[{"grant_number":"819603","call_identifier":"H2020","_id":"0aacfa84-070f-11eb-9043-d7eb2c709234","name":"Learning the shape of synaptic plasticity rules for neuronal architectures and function through machine learning."}],"OA_type":"hybrid","date_updated":"2025-09-04T13:06:06Z","ddc":["570"],"OA_place":"publisher","intvolume":"        27","page":"964-974","pmid":1,"author":[{"full_name":"Agnes, Everton J.","first_name":"Everton J.","last_name":"Agnes"},{"id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","full_name":"Vogels, Tim P","first_name":"Tim P","orcid":"0000-0003-3295-6181","last_name":"Vogels"}],"month":"05","volume":27,"file_date_updated":"2025-06-25T08:45:32Z","publication_status":"published","year":"2024","_id":"15171","quality_controlled":"1","date_published":"2024-05-01T00:00:00Z","publisher":"Springer Nature","acknowledgement":"We thank C. Currin, B. Podlaski and the members of the Vogels group for fruitful discussions. E.J.A. and T.P.V. were supported by a Research Project Grant from the Leverhulme Trust (RPG-2016-446; TPV), a Sir Henry Dale Fellowship from the Wellcome Trust and the Royal Society (WT100000; T.P.V.), a Wellcome Trust Senior Research Fellowship (214316/Z/18/Z; T.P.V.) and a European Research Council Consolidator Grant (SYNAPSEEK, 819603; T.P.V.). For the purpose of open access, the authors have applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. Open access funding provided by University of Basel.","file":[{"date_updated":"2025-06-25T08:45:32Z","file_id":"19902","file_name":"2025_NatureNeuroscience_Agnes.pdf","checksum":"dfca68a24749575b912b3a78a7de4516","success":1,"file_size":10508018,"content_type":"application/pdf","date_created":"2025-06-25T08:45:32Z","access_level":"open_access","relation":"main_file","creator":"dernst"}],"doi":"10.1038/s41593-024-01597-4","isi":1,"publication_identifier":{"eissn":["1546-1726"],"issn":["1097-6256"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","department":[{"_id":"TiVo"}],"day":"01","oa":1,"title":"Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"publication_identifier":{"eissn":["1557-9654"],"issn":["0018-9448"]},"article_processing_charge":"No","oa":1,"title":"Concentration without independence via information measures","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"MaMo"}],"day":"01","quality_controlled":"1","_id":"15172","date_published":"2024-06-01T00:00:00Z","publisher":"IEEE","isi":1,"doi":"10.1109/TIT.2024.3367767","author":[{"id":"9583e921-e1ad-11ec-9862-cef099626dc9","full_name":"Esposito, Amedeo Roberto","first_name":"Amedeo Roberto","last_name":"Esposito"},{"full_name":"Mondelli, Marco","id":"27EB676C-8706-11E9-9510-7717E6697425","last_name":"Mondelli","orcid":"0000-0002-3242-7020","first_name":"Marco"}],"page":"3823-3839","publication_status":"published","year":"2024","month":"06","related_material":{"record":[{"id":"14922","status":"public","relation":"earlier_version"}]},"issue":"6","volume":70,"abstract":[{"text":"We propose a novel approach to concentration for non-independent random variables. The main idea is to “pretend” that the random variables are independent and pay a multiplicative price measuring how far they are from actually being independent. This price is encapsulated in the Hellinger integral between the joint and the product of the marginals, which is then upper bounded leveraging tensorisation properties. Our bounds represent a natural generalisation of concentration inequalities in the presence of dependence: we recover exactly the classical bounds (McDiarmid’s inequality) when the random variables are independent. Furthermore, in a “large deviations” regime, we obtain the same decay in the probability as for the independent case, even when the random variables display non-trivial dependencies. To show this, we consider a number of applications of interest. First, we provide a bound for Markov chains with finite state space. Then, we consider the Simple Symmetric Random Walk, which is a non-contracting Markov chain, and a non-Markovian setting in which the stochastic process depends on its entire past. To conclude, we propose an application to Markov Chain Monte Carlo methods, where our approach leads to an improved lower bound on the minimum burn-in period required to reach a certain accuracy. In all of these settings, we provide a regime of parameters in which our bound fares better than what the state of the art can provide.","lang":"eng"}],"status":"public","external_id":{"arxiv":["2303.07245"],"isi":["001230181100001"]},"publication":"IEEE Transactions on Information Theory","scopus_import":"1","date_created":"2024-03-24T23:01:00Z","oa_version":"Preprint","corr_author":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2303.07245"}],"type":"journal_article","citation":{"chicago":"Esposito, Amedeo Roberto, and Marco Mondelli. “Concentration without Independence via Information Measures.” <i>IEEE Transactions on Information Theory</i>. IEEE, 2024. <a href=\"https://doi.org/10.1109/TIT.2024.3367767\">https://doi.org/10.1109/TIT.2024.3367767</a>.","short":"A.R. Esposito, M. Mondelli, IEEE Transactions on Information Theory 70 (2024) 3823–3839.","mla":"Esposito, Amedeo Roberto, and Marco Mondelli. “Concentration without Independence via Information Measures.” <i>IEEE Transactions on Information Theory</i>, vol. 70, no. 6, IEEE, 2024, pp. 3823–39, doi:<a href=\"https://doi.org/10.1109/TIT.2024.3367767\">10.1109/TIT.2024.3367767</a>.","ista":"Esposito AR, Mondelli M. 2024. Concentration without independence via information measures. IEEE Transactions on Information Theory. 70(6), 3823–3839.","ama":"Esposito AR, Mondelli M. Concentration without independence via information measures. <i>IEEE Transactions on Information Theory</i>. 2024;70(6):3823-3839. doi:<a href=\"https://doi.org/10.1109/TIT.2024.3367767\">10.1109/TIT.2024.3367767</a>","ieee":"A. R. Esposito and M. Mondelli, “Concentration without independence via information measures,” <i>IEEE Transactions on Information Theory</i>, vol. 70, no. 6. IEEE, pp. 3823–3839, 2024.","apa":"Esposito, A. R., &#38; Mondelli, M. (2024). Concentration without independence via information measures. <i>IEEE Transactions on Information Theory</i>. IEEE. <a href=\"https://doi.org/10.1109/TIT.2024.3367767\">https://doi.org/10.1109/TIT.2024.3367767</a>"},"article_type":"original","language":[{"iso":"eng"}],"date_updated":"2025-09-04T13:06:53Z","arxiv":1,"intvolume":"        70","project":[{"_id":"059876FA-7A3F-11EA-A408-12923DDC885E","name":"Prix Lopez-Loretta 2019 - Marco Mondelli"}]},{"pmid":1,"author":[{"full_name":"Palkina, Kseniia A.","first_name":"Kseniia A.","last_name":"Palkina"},{"full_name":"Karataeva, Tatiana A.","first_name":"Tatiana A.","last_name":"Karataeva"},{"last_name":"Perfilov","first_name":"Maxim M.","full_name":"Perfilov, Maxim M."},{"last_name":"Fakhranurova","first_name":"Liliia I.","full_name":"Fakhranurova, Liliia I."},{"last_name":"Markina","first_name":"Nadezhda M.","full_name":"Markina, Nadezhda M."},{"orcid":"0000-0001-9139-5383","first_name":"Louisa","last_name":"Gonzalez Somermeyer","full_name":"Gonzalez Somermeyer, Louisa","id":"4720D23C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Garcia-Perez","first_name":"Elena","full_name":"Garcia-Perez, Elena"},{"full_name":"Vazquez-Vilar, Marta","first_name":"Marta","last_name":"Vazquez-Vilar"},{"first_name":"Marta","last_name":"Rodriguez-Rodriguez","full_name":"Rodriguez-Rodriguez, Marta"},{"full_name":"Vazquez-Vilriales, Victor","last_name":"Vazquez-Vilriales","first_name":"Victor"},{"full_name":"Shakhova, Ekaterina S.","first_name":"Ekaterina S.","last_name":"Shakhova"},{"full_name":"Mitiouchkina, Tatiana","first_name":"Tatiana","last_name":"Mitiouchkina"},{"full_name":"Belozerova, Olga A.","last_name":"Belozerova","first_name":"Olga A."},{"full_name":"Kovalchuk, Sergey I.","first_name":"Sergey I.","last_name":"Kovalchuk"},{"full_name":"Alekberova, Anna","first_name":"Anna","last_name":"Alekberova"},{"full_name":"Malyshevskaia, Alena K.","last_name":"Malyshevskaia","first_name":"Alena K."},{"full_name":"Bugaeva, Evgenia N.","last_name":"Bugaeva","first_name":"Evgenia N."},{"last_name":"Guglya","first_name":"Elena B.","full_name":"Guglya, Elena B."},{"full_name":"Balakireva, Anastasia","first_name":"Anastasia","last_name":"Balakireva"},{"full_name":"Sytov, Nikita","last_name":"Sytov","first_name":"Nikita"},{"full_name":"Bezlikhotnova, Anastasia","last_name":"Bezlikhotnova","first_name":"Anastasia"},{"last_name":"Boldyreva","first_name":"Daria I.","full_name":"Boldyreva, Daria I."},{"last_name":"Babenko","first_name":"Vladislav V.","full_name":"Babenko, Vladislav V."},{"last_name":"Kondrashov","first_name":"Fyodor","orcid":"0000-0001-8243-4694","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87","full_name":"Kondrashov, Fyodor"},{"full_name":"Choob, Vladimir V.","first_name":"Vladimir V.","last_name":"Choob"},{"full_name":"Orzaez, Diego","last_name":"Orzaez","first_name":"Diego"},{"full_name":"Yampolsky, Ilia V.","last_name":"Yampolsky","first_name":"Ilia V."},{"first_name":"Alexander S.","last_name":"Mishin","full_name":"Mishin, Alexander S."},{"full_name":"Sarkisyan, Karen S.","last_name":"Sarkisyan","first_name":"Karen S."}],"month":"03","volume":10,"issue":"10","publication_status":"published","file_date_updated":"2024-03-25T09:42:10Z","year":"2024","language":[{"iso":"eng"}],"DOAJ_listed":"1","article_type":"original","citation":{"short":"K.A. Palkina, T.A. Karataeva, M.M. Perfilov, L.I. Fakhranurova, N.M. Markina, L. Gonzalez Somermeyer, E. Garcia-Perez, M. Vazquez-Vilar, M. Rodriguez-Rodriguez, V. Vazquez-Vilriales, E.S. Shakhova, T. Mitiouchkina, O.A. Belozerova, S.I. Kovalchuk, A. Alekberova, A.K. Malyshevskaia, E.N. Bugaeva, E.B. Guglya, A. Balakireva, N. Sytov, A. Bezlikhotnova, D.I. Boldyreva, V.V. Babenko, F. Kondrashov, V.V. Choob, D. Orzaez, I.V. Yampolsky, A.S. Mishin, K.S. Sarkisyan, Science Advances 10 (2024).","mla":"Palkina, Kseniia A., et al. “A Hybrid Pathway for Self-Sustained Luminescence.” <i>Science Advances</i>, vol. 10, no. 10, adk1992, American Association for the Advancement of Science, 2024, doi:<a href=\"https://doi.org/10.1126/sciadv.adk1992\">10.1126/sciadv.adk1992</a>.","ieee":"K. A. Palkina <i>et al.</i>, “A hybrid pathway for self-sustained luminescence,” <i>Science Advances</i>, vol. 10, no. 10. American Association for the Advancement of Science, 2024.","ista":"Palkina KA, Karataeva TA, Perfilov MM, Fakhranurova LI, Markina NM, Gonzalez Somermeyer L, Garcia-Perez E, Vazquez-Vilar M, Rodriguez-Rodriguez M, Vazquez-Vilriales V, Shakhova ES, Mitiouchkina T, Belozerova OA, Kovalchuk SI, Alekberova A, Malyshevskaia AK, Bugaeva EN, Guglya EB, Balakireva A, Sytov N, Bezlikhotnova A, Boldyreva DI, Babenko VV, Kondrashov F, Choob VV, Orzaez D, Yampolsky IV, Mishin AS, Sarkisyan KS. 2024. A hybrid pathway for self-sustained luminescence. Science Advances. 10(10), adk1992.","ama":"Palkina KA, Karataeva TA, Perfilov MM, et al. A hybrid pathway for self-sustained luminescence. <i>Science Advances</i>. 2024;10(10). doi:<a href=\"https://doi.org/10.1126/sciadv.adk1992\">10.1126/sciadv.adk1992</a>","apa":"Palkina, K. A., Karataeva, T. A., Perfilov, M. M., Fakhranurova, L. I., Markina, N. M., Gonzalez Somermeyer, L., … Sarkisyan, K. S. (2024). A hybrid pathway for self-sustained luminescence. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.adk1992\">https://doi.org/10.1126/sciadv.adk1992</a>","chicago":"Palkina, Kseniia A., Tatiana A. Karataeva, Maxim M. Perfilov, Liliia I. Fakhranurova, Nadezhda M. Markina, Louisa Gonzalez Somermeyer, Elena Garcia-Perez, et al. “A Hybrid Pathway for Self-Sustained Luminescence.” <i>Science Advances</i>. American Association for the Advancement of Science, 2024. <a href=\"https://doi.org/10.1126/sciadv.adk1992\">https://doi.org/10.1126/sciadv.adk1992</a>."},"has_accepted_license":"1","external_id":{"pmid":["38457503"],"isi":["001187580500013"]},"status":"public","abstract":[{"text":"The fungal bioluminescence pathway can be reconstituted in other organisms allowing luminescence imaging without exogenously supplied substrate. The pathway starts from hispidin biosynthesis—a step catalyzed by a large fungal polyketide synthase that requires a posttranslational modification for activity. Here, we report identification of alternative compact hispidin synthases encoded by a phylogenetically diverse group of plants. A hybrid bioluminescence pathway that combines plant and fungal genes is more compact, not dependent on availability of machinery for posttranslational modifications, and confers autonomous bioluminescence in yeast, mammalian, and plant hosts. The compact size of plant hispidin synthases enables additional modes of delivery of autoluminescence, such as delivery with viral vectors.","lang":"eng"}],"type":"journal_article","scopus_import":"1","date_created":"2024-03-25T08:54:33Z","oa_version":"Published Version","publication":"Science Advances","OA_type":"gold","ddc":["580"],"date_updated":"2025-09-04T13:16:05Z","intvolume":"        10","OA_place":"publisher","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["2375-2548"]},"article_processing_charge":"Yes","department":[{"_id":"FyKo"}],"day":"01","title":"A hybrid pathway for self-sustained luminescence","oa":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_number":"adk1992","_id":"15179","date_published":"2024-03-01T00:00:00Z","quality_controlled":"1","publisher":"American Association for the Advancement of Science","file":[{"file_name":"2024_ScienceAdv_Palkina.pdf","file_id":"15185","date_updated":"2024-03-25T09:42:10Z","checksum":"a19c43b260ea0bbaf895a29712e3153c","success":1,"file_size":1499302,"date_created":"2024-03-25T09:42:10Z","content_type":"application/pdf","access_level":"open_access","creator":"dernst","relation":"main_file"}],"doi":"10.1126/sciadv.adk1992","acknowledgement":"We thank Milaboratory (milaboratory.com) for the access to computing and storage infrastructure. We thank J. Petrasek for providing the BY-2 cell culture line. We thank Konstantin Lukyanov laboratory and Sergey Deyev laboratory for assistance with experiments.\r\nThis study was partially funded by Light Bio and Planta. The Synthetic biology Group is funded by the MRC London Institute of Medical Sciences (UKRI MC-A658-5QEA0). Cloning and luminescent assays performed in BY-2 were partially supported by RSF, project number 22-14-00400, https://rscf.ru/project/22-14-00400/. Plant transformations were funded by RFBR and MOST, project number 21-54-52004. Plant imaging experiments were funded by RSF, project number 22-74-00124, https://rscf.ru/project/22-74-00124/. Viral delivery experiments were funded by the grant PID2019-108203RB-I00 Plan Nacional I + D from the Ministerio de Ciencia e Innovación (Spain) through the Agencia Estatal de Investigación (cofinanced by the European Regional Development Fund).","isi":1},{"title":"Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"MiLe"}],"day":"01","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["2643-1564"]},"article_processing_charge":"Yes","publisher":"American Physical Society","acknowledgement":"This work has been funded by the Cluster of Excellence “Advanced Imaging of Matter” of the Deutsche Forschungsgemeinschaft (DFG) - EXC 2056 - Project ID 390715994.\r\nG.M.K. gratefully acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.","file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","date_created":"2024-03-25T09:24:55Z","content_type":"application/pdf","file_size":2207067,"success":1,"checksum":"4e0e58d1f58386fb016284c84db2a300","date_updated":"2024-03-25T09:24:55Z","file_id":"15183","file_name":"2024_PhysicalReviewResearch_Becker.pdf"}],"doi":"10.1103/physrevresearch.6.013257","article_number":"013257","_id":"15181","date_published":"2024-03-01T00:00:00Z","quality_controlled":"1","publication_status":"published","file_date_updated":"2024-03-25T09:24:55Z","year":"2024","month":"03","volume":6,"issue":"1","author":[{"first_name":"A.","last_name":"Becker","full_name":"Becker, A."},{"last_name":"Koutentakis","first_name":"Georgios","id":"d7b23d3a-9e21-11ec-b482-f76739596b95","full_name":"Koutentakis, Georgios"},{"first_name":"P.","last_name":"Schmelcher","full_name":"Schmelcher, P."}],"ddc":["530"],"arxiv":1,"date_updated":"2025-05-14T09:32:03Z","intvolume":"         6","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413"}],"external_id":{"arxiv":["2310.17995"]},"status":"public","has_accepted_license":"1","abstract":[{"lang":"eng","text":"We demonstrate the failure of the adiabatic Born-Oppenheimer approximation to describe the ground state of a quantum impurity within an ultracold Fermi gas despite substantial mass differences between the bath and impurity species. Increasing repulsion leads to the appearance of nonadiabatic couplings between the fast bath and slow impurity degrees of freedom, which reduce the parity symmetry of the latter according to the pseudo Jahn-Teller effect. The presence of this mechanism is associated to a conical intersection involving the impurity position and the inverse of the interaction strength, which acts as a synthetic dimension. We elucidate the presence of these effects via a detailed ground-state analysis involving the comparison of ab initio fully correlated simulations with effective models. Our study suggests ultracold atomic ensembles as potent emulators of complex molecular phenomena."}],"type":"journal_article","publication":"Physical Review Research","date_created":"2024-03-25T08:57:07Z","scopus_import":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"ec_funded":1,"article_type":"original","citation":{"chicago":"Becker, A., Georgios Koutentakis, and P. Schmelcher. “Synthetic Dimension-Induced Pseudo Jahn-Teller Effect in One-Dimensional Confined Fermions.” <i>Physical Review Research</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">https://doi.org/10.1103/physrevresearch.6.013257</a>.","ieee":"A. Becker, G. Koutentakis, and P. Schmelcher, “Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions,” <i>Physical Review Research</i>, vol. 6, no. 1. American Physical Society, 2024.","ista":"Becker A, Koutentakis G, Schmelcher P. 2024. Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions. Physical Review Research. 6(1), 013257.","ama":"Becker A, Koutentakis G, Schmelcher P. Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions. <i>Physical Review Research</i>. 2024;6(1). doi:<a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">10.1103/physrevresearch.6.013257</a>","apa":"Becker, A., Koutentakis, G., &#38; Schmelcher, P. (2024). Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">https://doi.org/10.1103/physrevresearch.6.013257</a>","short":"A. Becker, G. Koutentakis, P. Schmelcher, Physical Review Research 6 (2024).","mla":"Becker, A., et al. “Synthetic Dimension-Induced Pseudo Jahn-Teller Effect in One-Dimensional Confined Fermions.” <i>Physical Review Research</i>, vol. 6, no. 1, 013257, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">10.1103/physrevresearch.6.013257</a>."},"DOAJ_listed":"1"},{"quality_controlled":"1","_id":"15186","date_published":"2024-03-19T00:00:00Z","article_number":" e2023GL106523","file":[{"file_size":1280108,"checksum":"eacb011091a503b9e7b748fef639ba4c","success":1,"date_updated":"2024-03-25T11:28:25Z","file_id":"15187","file_name":"2024_GeophysResLetters_Hwong.pdf","relation":"main_file","creator":"dernst","access_level":"open_access","date_created":"2024-03-25T11:28:25Z","content_type":"application/pdf"}],"isi":1,"acknowledgement":"YLH is supported by funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant 101034413. CM gratefully acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant 805041). The authors warmly thank Steven Sherwood, Jiawei Bao, Bidyut Goswami, and Martin Janssens for stimulating and helpful discussions. They also thank Christopher Holloway and an anonymous reviewer for providing helpful feedback that greatly improved this manuscript.\r\n","doi":"10.1029/2023gl106523","publisher":"Wiley","APC_amount":"2940 EUR","article_processing_charge":"Yes","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"publication_identifier":{"issn":["0094-8276"],"eissn":["1944-8007"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation","oa":1,"day":"19","keyword":["General Earth and Planetary Sciences","Geophysics"],"department":[{"_id":"CaMu"}],"type":"journal_article","corr_author":"1","publication":"Geophysical Research Letters","oa_version":"Published Version","scopus_import":"1","date_created":"2024-03-25T10:27:30Z","status":"public","has_accepted_license":"1","external_id":{"isi":["001187002300001"]},"abstract":[{"text":"The elimination of rain evaporation in the planetary boundary layer (PBL) has been found to lead to convective self‐aggregation (CSA) even without radiative feedback, but the precise mechanisms underlying this phenomenon remain unclear. We conducted cloud‐resolving simulations with two domain sizes and progressively reduced rain evaporation in the PBL. Surprisingly, CSA only occurred when rain evaporation was almost completely removed. The additional convective heating resulting from the reduction of evaporative cooling in the moist patch was found to be the trigger, thereafter a dry subsidence intrusion into the PBL in the dry patch takes over and sets CSA in motion. Temperature and moisture anomalies oppose each other in their buoyancy effects, hence explaining the need for almost total rain evaporation removal. We also found radiative cooling and not cold pools to be the leading cause for the comparative ease of CSA to take place in the larger domain.","lang":"eng"}],"language":[{"iso":"eng"}],"article_type":"original","ec_funded":1,"DOAJ_listed":"1","citation":{"apa":"Hwong, Y.-L., &#38; Muller, C. J. (2024). The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation. <i>Geophysical Research Letters</i>. Wiley. <a href=\"https://doi.org/10.1029/2023gl106523\">https://doi.org/10.1029/2023gl106523</a>","ieee":"Y.-L. Hwong and C. J. Muller, “The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation,” <i>Geophysical Research Letters</i>, vol. 51, no. 6. Wiley, 2024.","ista":"Hwong Y-L, Muller CJ. 2024. The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation. Geophysical Research Letters. 51(6), e2023GL106523.","ama":"Hwong Y-L, Muller CJ. The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation. <i>Geophysical Research Letters</i>. 2024;51(6). doi:<a href=\"https://doi.org/10.1029/2023gl106523\">10.1029/2023gl106523</a>","mla":"Hwong, Yi-Ling, and Caroline J. Muller. “The Unreasonable Efficiency of Total Rain Evaporation Removal in Triggering Convective Self‐aggregation.” <i>Geophysical Research Letters</i>, vol. 51, no. 6, e2023GL106523, Wiley, 2024, doi:<a href=\"https://doi.org/10.1029/2023gl106523\">10.1029/2023gl106523</a>.","short":"Y.-L. Hwong, C.J. Muller, Geophysical Research Letters 51 (2024).","chicago":"Hwong, Yi-Ling, and Caroline J Muller. “The Unreasonable Efficiency of Total Rain Evaporation Removal in Triggering Convective Self‐aggregation.” <i>Geophysical Research Letters</i>. Wiley, 2024. <a href=\"https://doi.org/10.1029/2023gl106523\">https://doi.org/10.1029/2023gl106523</a>."},"intvolume":"        51","OA_place":"publisher","ddc":["550"],"date_updated":"2025-09-04T13:16:39Z","OA_type":"gold","project":[{"grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"},{"grant_number":"805041","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","call_identifier":"H2020","_id":"629205d8-2b32-11ec-9570-e1356ff73576"}],"author":[{"first_name":"Yi-Ling","orcid":"0000-0001-9281-3479","last_name":"Hwong","id":"1217aa61-4dd1-11ec-9ac3-f2ba3f17ee22","full_name":"Hwong, Yi-Ling"},{"last_name":"Muller","orcid":"0000-0001-5836-5350","first_name":"Caroline J","full_name":"Muller, Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b"}],"year":"2024","file_date_updated":"2024-03-25T11:28:25Z","publication_status":"published","volume":51,"related_material":{"record":[{"relation":"research_data","id":"19307","status":"public"}]},"issue":"6","month":"03"},{"_id":"15247","date_published":"2024-08-01T00:00:00Z","quality_controlled":"1","article_number":"105889","acknowledgement":"We are grateful to Balázs Keszegh, and to the members of the Miklós Schweitzer Competition committee of 2022 for valuable discussions, and Shira Zerbib for pointing out several important mathematical typos.","doi":"10.1016/j.jcta.2024.105889","file":[{"creator":"dernst","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2025-01-09T08:37:20Z","file_size":366029,"success":1,"checksum":"ffc29d65e712849f0d31009271e06a63","file_id":"18791","file_name":"2024_JourCombiTheoryA_Frankl.pdf","date_updated":"2025-01-09T08:37:20Z"}],"isi":1,"publisher":"Elsevier","article_processing_charge":"No","publication_identifier":{"issn":["0097-3165"],"eissn":["1096-0899"]},"tmp":{"image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode"},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa":1,"title":"Odd-sunflowers","day":"01","department":[{"_id":"HeEd"}],"publication":"Journal of Combinatorial Theory, Series A","date_created":"2024-03-31T22:01:11Z","oa_version":"Published Version","scopus_import":"1","type":"journal_article","corr_author":"1","abstract":[{"lang":"eng","text":"Extending the notion of sunflowers, we call a family of at least two sets an odd-sunflower if every element of the underlying set is contained in an odd number of sets or in none of them. It follows from the Erdős–Szemerédi conjecture, recently proved by Naslund and Sawin, that there is a constant <2 such that every family of subsets of an n-element set that contains no odd-sunflower consists of at most n sets. We construct such families of size at least 1.5021n. We also characterize minimal odd-sunflowers of triples."}],"has_accepted_license":"1","external_id":{"isi":["001217739200001"],"arxiv":["2310.16701"]},"status":"public","citation":{"chicago":"Frankl, Peter, János Pach, and Dömötör Pálvölgyi. “Odd-Sunflowers.” <i>Journal of Combinatorial Theory, Series A</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">https://doi.org/10.1016/j.jcta.2024.105889</a>.","short":"P. Frankl, J. Pach, D. Pálvölgyi, Journal of Combinatorial Theory, Series A 206 (2024).","mla":"Frankl, Peter, et al. “Odd-Sunflowers.” <i>Journal of Combinatorial Theory, Series A</i>, vol. 206, no. 8, 105889, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">10.1016/j.jcta.2024.105889</a>.","ama":"Frankl P, Pach J, Pálvölgyi D. Odd-sunflowers. <i>Journal of Combinatorial Theory, Series A</i>. 2024;206(8). doi:<a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">10.1016/j.jcta.2024.105889</a>","ieee":"P. Frankl, J. Pach, and D. Pálvölgyi, “Odd-sunflowers,” <i>Journal of Combinatorial Theory, Series A</i>, vol. 206, no. 8. Elsevier, 2024.","ista":"Frankl P, Pach J, Pálvölgyi D. 2024. Odd-sunflowers. Journal of Combinatorial Theory, Series A. 206(8), 105889.","apa":"Frankl, P., Pach, J., &#38; Pálvölgyi, D. (2024). Odd-sunflowers. <i>Journal of Combinatorial Theory, Series A</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">https://doi.org/10.1016/j.jcta.2024.105889</a>"},"article_type":"original","language":[{"iso":"eng"}],"intvolume":"       206","OA_place":"publisher","date_updated":"2025-09-04T13:20:39Z","ddc":["510"],"arxiv":1,"OA_type":"hybrid","author":[{"full_name":"Frankl, Peter","first_name":"Peter","last_name":"Frankl"},{"first_name":"János","last_name":"Pach","full_name":"Pach, János","id":"E62E3130-B088-11EA-B919-BF823C25FEA4"},{"full_name":"Pálvölgyi, Dömötör","first_name":"Dömötör","last_name":"Pálvölgyi"}],"year":"2024","publication_status":"published","file_date_updated":"2025-01-09T08:37:20Z","issue":"8","volume":206,"month":"08"},{"department":[{"_id":"TaHa"}],"day":"01","title":"Mirror symmetry for parabolic Higgs bundles via p-adic integration","oa":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"issn":["0001-8708"],"eissn":["1090-2082"]},"article_processing_charge":"Yes (via OA deal)","publisher":"Elsevier","doi":"10.1016/j.aim.2024.109616","isi":1,"acknowledgement":"Shiyu Shen has received funding from the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413.","file":[{"content_type":"application/pdf","date_created":"2024-07-22T12:10:03Z","creator":"dernst","relation":"main_file","access_level":"open_access","success":1,"checksum":"68f2f08136ccf547891a16a2c0621e97","file_id":"17315","file_name":"2024_AdvancesMath_Shen.pdf","date_updated":"2024-07-22T12:10:03Z","file_size":702889}],"article_number":"109616","_id":"15248","date_published":"2024-05-01T00:00:00Z","quality_controlled":"1","month":"05","volume":443,"issue":"5","file_date_updated":"2024-07-22T12:10:03Z","publication_status":"published","year":"2024","author":[{"last_name":"Shen","orcid":"0000-0002-4444-8718","first_name":"Shiyu","full_name":"Shen, Shiyu","id":"544cccd3-9005-11ec-87bc-94aef1c5b814"}],"OA_type":"hybrid","project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"ddc":["510"],"arxiv":1,"date_updated":"2025-09-04T13:21:18Z","OA_place":"publisher","intvolume":"       443","language":[{"iso":"eng"}],"article_type":"original","citation":{"short":"S. Shen, Advances in Mathematics 443 (2024).","mla":"Shen, Shiyu. “Mirror Symmetry for Parabolic Higgs Bundles via P-Adic Integration.” <i>Advances in Mathematics</i>, vol. 443, no. 5, 109616, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.aim.2024.109616\">10.1016/j.aim.2024.109616</a>.","ista":"Shen S. 2024. Mirror symmetry for parabolic Higgs bundles via p-adic integration. Advances in Mathematics. 443(5), 109616.","ieee":"S. Shen, “Mirror symmetry for parabolic Higgs bundles via p-adic integration,” <i>Advances in Mathematics</i>, vol. 443, no. 5. Elsevier, 2024.","ama":"Shen S. Mirror symmetry for parabolic Higgs bundles via p-adic integration. <i>Advances in Mathematics</i>. 2024;443(5). doi:<a href=\"https://doi.org/10.1016/j.aim.2024.109616\">10.1016/j.aim.2024.109616</a>","apa":"Shen, S. (2024). Mirror symmetry for parabolic Higgs bundles via p-adic integration. <i>Advances in Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.aim.2024.109616\">https://doi.org/10.1016/j.aim.2024.109616</a>","chicago":"Shen, Shiyu. “Mirror Symmetry for Parabolic Higgs Bundles via P-Adic Integration.” <i>Advances in Mathematics</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.aim.2024.109616\">https://doi.org/10.1016/j.aim.2024.109616</a>."},"ec_funded":1,"external_id":{"arxiv":["2302.02817"],"isi":["001216128200001"]},"status":"public","has_accepted_license":"1","abstract":[{"text":"Applying the technique of p-adic integration, we prove the topological mirror symmetry conjecture of Hausel-Thaddeus for the moduli spaces of (strongly) parabolic Higgs bundles for the structure groups SLn and PGLn, building on previous work of Groechenig-Wyss-Ziegler on the non-parabolic case. We also prove the E-polynomial of the smooth moduli space of parabolic GLn-Higgs bundles is independent of the degree of the underlying vector bundles.","lang":"eng"}],"type":"journal_article","corr_author":"1","scopus_import":"1","publication":"Advances in Mathematics","oa_version":"Published Version","date_created":"2024-03-31T22:01:11Z"},{"_id":"15249","date_published":"2024-04-01T00:00:00Z","quality_controlled":"1","isi":1,"doi":"10.1093/mnras/stae673","acknowledgement":"We thank the referee for constructive comments that helped improving the paper. Based on observations collected at the European Southern Observatory under ESO programme 1101.A-0127. Funded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. GP acknowledges support from the Netherlands Research School for Astronomy (Nederlandse Onderzoekschool Voor Astronomie, NOVA). JB acknowledges financial support from the Fundação para a Ciência e a Tecnologia (FCT) through national funds PTDC/FIS-AST/4862/2020, work contract 2020.03379.CEECIND, and research grants UIDB/04434/2020 and UIDP/04434/2020. TU and LW acknowledge funding by the European Research Council through ERC-AdG SPECMAP-CGM, GA 101020943. TG is supported by the ERC Starting grant 757258 ‘TRIPLE’.","file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","content_type":"application/pdf","date_created":"2024-04-02T08:42:17Z","file_size":2626735,"success":1,"checksum":"1e65c40a71e565eebdc4c5ff11822ba2","date_updated":"2024-04-02T08:42:17Z","file_id":"15255","file_name":"2024_MonthlyNRoyalAstronSoc_Matthee.pdf"}],"publisher":"Oxford University Press","article_processing_charge":"Yes","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"day":"01","department":[{"_id":"JoMa"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field","oa":1,"language":[{"iso":"eng"}],"DOAJ_listed":"1","citation":{"short":"J.J. Matthee, C. Golling, R. Mackenzie, G. Pezzulli, S. Lilly, J. Schaye, R. Bacon, H. Kusakabe, T. Urrutia, L. Boogaard, J. Brinchmann, M.V. Maseda, T. Garel, N.F. Bouché, L. Wisotzki, Monthly Notices of the Royal Astronomical Society 529 (2024) 2794–2806.","mla":"Matthee, Jorryt J., et al. “Large-Scale Excess H I Absorption around z ≈ 4 Galaxies Detected in a Background Galaxy Spectrum in the MUSE EXtremely Deep Field.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 529, no. 3, Oxford University Press, 2024, pp. 2794–806, doi:<a href=\"https://doi.org/10.1093/mnras/stae673\">10.1093/mnras/stae673</a>.","ista":"Matthee JJ, Golling C, Mackenzie R, Pezzulli G, Lilly S, Schaye J, Bacon R, Kusakabe H, Urrutia T, Boogaard L, Brinchmann J, Maseda MV, Garel T, Bouché NF, Wisotzki L. 2024. Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field. Monthly Notices of the Royal Astronomical Society. 529(3), 2794–2806.","ama":"Matthee JJ, Golling C, Mackenzie R, et al. Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field. <i>Monthly Notices of the Royal Astronomical Society</i>. 2024;529(3):2794-2806. doi:<a href=\"https://doi.org/10.1093/mnras/stae673\">10.1093/mnras/stae673</a>","ieee":"J. J. Matthee <i>et al.</i>, “Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 529, no. 3. Oxford University Press, pp. 2794–2806, 2024.","apa":"Matthee, J. J., Golling, C., Mackenzie, R., Pezzulli, G., Lilly, S., Schaye, J., … Wisotzki, L. (2024). Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stae673\">https://doi.org/10.1093/mnras/stae673</a>","chicago":"Matthee, Jorryt J, Christopher Golling, Ruari Mackenzie, Gabriele Pezzulli, Simon Lilly, Joop Schaye, Roland Bacon, et al. “Large-Scale Excess H I Absorption around z ≈ 4 Galaxies Detected in a Background Galaxy Spectrum in the MUSE EXtremely Deep Field.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/mnras/stae673\">https://doi.org/10.1093/mnras/stae673</a>."},"article_type":"original","corr_author":"1","type":"journal_article","scopus_import":"1","publication":"Monthly Notices of the Royal Astronomical Society","oa_version":"Published Version","date_created":"2024-03-31T22:01:12Z","external_id":{"arxiv":["2305.15346"],"isi":["001188770300019"]},"status":"public","has_accepted_license":"1","abstract":[{"lang":"eng","text":"Observationally mapping the relation between galaxies and the intergalactic medium (IGM) is of key interest for studies of cosmic reionization. Diffuse hydrogen gas has typically been observed in H I Lyman-α (Lyα) absorption in the spectra of bright background quasars. However, it is important to extend these measurements to background galaxies as quasars become increasingly rare at high redshift and rarely probe closely separated sight lines. Here, we use deep integral field spectroscopy in the MUSE eXtremely Deep Field to demonstrate the measurement of the Lyα transmission at z ≈ 4 in absorption to a background galaxy at z = 4.77. The H I transmission is consistent with independent quasar sight lines at similar redshifts. Exploiting the high number of spectroscopic redshifts of faint galaxies (500 between z = 4.0–4.7 within a radius of 8 arcmin) that are tracers of the density field, we show that Lyα transmission is inversely correlated with galaxy density, i.e. transparent regions in the Lyα forest mark underdense regions at z ≈ 4. Due to large-scale clustering, galaxies are surrounded by excess H I absorption over the cosmic mean out to 4 cMpc/h70. We also find that redshifts from the peak of the Lyα line are typically offset from the systemic redshift by +170 km s−1. This work extends results from z ≈ 2–3 to higher redshifts and demonstrates the power of deep integral field spectroscopy to simultaneously measure the ionization structure of the IGM and the large-scale density field in the early Universe."}],"project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","name":"Young galaxies as tracers and agents of cosmic reionization","grant_number":"101076224"}],"OA_type":"gold","OA_place":"publisher","intvolume":"       529","ddc":["520"],"arxiv":1,"date_updated":"2025-09-04T13:18:02Z","page":"2794-2806","author":[{"full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","last_name":"Matthee","orcid":"0000-0003-2871-127X","first_name":"Jorryt J"},{"full_name":"Golling, Christopher","last_name":"Golling","first_name":"Christopher"},{"first_name":"Ruari","last_name":"Mackenzie","full_name":"Mackenzie, Ruari"},{"full_name":"Pezzulli, Gabriele","first_name":"Gabriele","last_name":"Pezzulli"},{"last_name":"Lilly","first_name":"Simon","full_name":"Lilly, Simon"},{"last_name":"Schaye","first_name":"Joop","full_name":"Schaye, Joop"},{"full_name":"Bacon, Roland","last_name":"Bacon","first_name":"Roland"},{"first_name":"Haruka","last_name":"Kusakabe","full_name":"Kusakabe, Haruka"},{"full_name":"Urrutia, Tanya","first_name":"Tanya","last_name":"Urrutia"},{"first_name":"Leindert","last_name":"Boogaard","full_name":"Boogaard, Leindert"},{"last_name":"Brinchmann","first_name":"Jarle","full_name":"Brinchmann, Jarle"},{"full_name":"Maseda, Michael V.","first_name":"Michael V.","last_name":"Maseda"},{"full_name":"Garel, Thibault","last_name":"Garel","first_name":"Thibault"},{"last_name":"Bouché","first_name":"Nicolas F.","full_name":"Bouché, Nicolas F."},{"last_name":"Wisotzki","first_name":"Lutz","full_name":"Wisotzki, Lutz"}],"volume":529,"issue":"3","month":"04","year":"2024","publication_status":"published","file_date_updated":"2024-04-02T08:42:17Z"},{"article_number":"e2319686121","_id":"15250","date_published":"2024-03-26T00:00:00Z","quality_controlled":"1","publisher":"National Academy of Sciences","file":[{"creator":"dernst","relation":"main_file","access_level":"open_access","date_created":"2024-04-02T08:54:28Z","content_type":"application/pdf","file_size":2483787,"success":1,"checksum":"06f9e60b1146a685d58bf33999422fa8","file_name":"2024_PNAS_Boytsov.pdf","file_id":"15256","date_updated":"2024-04-02T08:54:28Z"}],"doi":"10.1073/pnas.2319686121","isi":1,"acknowledgement":"We thank the Metabolomics Facility at Vienna BioCenter Core Facilities, which is a member of the Vienna BioCenter and funded by the City of Vienna through the Vienna Business Agency (shared research facility), for the LC–MS/MS analysis; and the BioImaging Facility at IST Austria for technical support and assistance. The authors want to thank N. Kastner for help with the live  cell  imaging  and  A.  Korošec  for  help  with  flow  cytometry.  This  work  was  supported by the Austrian Science Fund (FWF), grant P 36621- B (to M.R.), grant P 36667 (to W.S.), and core funding from IST Austria (to D.S.).","publication_identifier":{"eissn":["1091-6490"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (in subscription journal)","department":[{"_id":"DaSi"}],"day":"26","oa":1,"title":"Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_type":"original","citation":{"mla":"Boytsov, Danila, et al. “Orphan Lysosomal Solute Carrier MFSD1 Facilitates Highly Selective Dipeptide Transport.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 13, e2319686121, National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2319686121\">10.1073/pnas.2319686121</a>.","short":"D. Boytsov, G.M. Madej, G. Horn, N. Blaha, T. Köcher, H.H. Sitte, D.E. Siekhaus, C. Ziegler, W. Sandtner, M. Roblek, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","apa":"Boytsov, D., Madej, G. M., Horn, G., Blaha, N., Köcher, T., Sitte, H. H., … Roblek, M. (2024). Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2319686121\">https://doi.org/10.1073/pnas.2319686121</a>","ama":"Boytsov D, Madej GM, Horn G, et al. Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(13). doi:<a href=\"https://doi.org/10.1073/pnas.2319686121\">10.1073/pnas.2319686121</a>","ista":"Boytsov D, Madej GM, Horn G, Blaha N, Köcher T, Sitte HH, Siekhaus DE, Ziegler C, Sandtner W, Roblek M. 2024. Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport. Proceedings of the National Academy of Sciences of the United States of America. 121(13), e2319686121.","ieee":"D. Boytsov <i>et al.</i>, “Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 13. National Academy of Sciences, 2024.","chicago":"Boytsov, Danila, Gregor M. Madej, Georg Horn, Nadine Blaha, Thomas Köcher, Harald H. Sitte, Daria E Siekhaus, Christine Ziegler, Walter Sandtner, and Marko Roblek. “Orphan Lysosomal Solute Carrier MFSD1 Facilitates Highly Selective Dipeptide Transport.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2319686121\">https://doi.org/10.1073/pnas.2319686121</a>."},"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Orphan solute carrier (SLC) represents a group of membrane transporters whose exact functions and substrate specificities are not known. Elucidating the function and regulation of orphan SLC transporters is not only crucial for advancing our knowledge of cellular and molecular biology but can potentially lead to the development of new therapeutic strategies. Here, we provide evidence for the biological function of a ubiquitous orphan lysosomal SLC, the Major Facilitator Superfamily Domain-containing Protein 1 (MFSD1), which has remained phylogenetically unassigned. Targeted metabolomics revealed that dipeptides containing either lysine or arginine residues accumulate in lysosomes of cells lacking MFSD1. Whole-cell patch-clamp electrophysiological recordings of HEK293-cells expressing MFSD1 on the cell surface displayed transport affinities for positively charged dipeptides in the lower mM range, while dipeptides that carry a negative net charge were not transported. This was also true for single amino acids and tripeptides, which MFSD1 failed to transport. Our results identify MFSD1 as a highly selective lysosomal lysine/arginine/histidine-containing dipeptide exporter, which functions as a uniporter."}],"status":"public","external_id":{"isi":["001206419000003"],"pmid":["38507452"]},"has_accepted_license":"1","scopus_import":"1","oa_version":"Published Version","publication":"Proceedings of the National Academy of Sciences of the United States of America","date_created":"2024-03-31T22:01:12Z","corr_author":"1","type":"journal_article","date_updated":"2025-09-04T13:19:02Z","ddc":["570"],"intvolume":"       121","pmid":1,"acknowledged_ssus":[{"_id":"Bio"}],"author":[{"full_name":"Boytsov, Danila","last_name":"Boytsov","first_name":"Danila"},{"full_name":"Madej, Gregor M.","last_name":"Madej","first_name":"Gregor M."},{"first_name":"Georg","last_name":"Horn","full_name":"Horn, Georg"},{"full_name":"Blaha, Nadine","last_name":"Blaha","first_name":"Nadine"},{"last_name":"Köcher","first_name":"Thomas","full_name":"Köcher, Thomas"},{"full_name":"Sitte, Harald H.","first_name":"Harald H.","last_name":"Sitte"},{"last_name":"Siekhaus","first_name":"Daria E","orcid":"0000-0001-8323-8353","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","full_name":"Siekhaus, Daria E"},{"first_name":"Christine","last_name":"Ziegler","full_name":"Ziegler, Christine"},{"first_name":"Walter","last_name":"Sandtner","full_name":"Sandtner, Walter"},{"id":"3047D808-F248-11E8-B48F-1D18A9856A87","full_name":"Roblek, Marko","first_name":"Marko","orcid":"0000-0001-9588-1389","last_name":"Roblek"}],"month":"03","issue":"13","volume":121,"file_date_updated":"2024-04-02T08:54:28Z","publication_status":"published","year":"2024"},{"volume":383,"issue":"6689","month":"03","year":"2024","publication_status":"published","pmid":1,"page":"eadj4591","author":[{"full_name":"Ying, Wei","first_name":"Wei","last_name":"Ying"},{"last_name":"Wang","first_name":"Yaowei","full_name":"Wang, Yaowei"},{"first_name":"Hong","last_name":"Wei","full_name":"Wei, Hong"},{"full_name":"Luo, Yongming","first_name":"Yongming","last_name":"Luo"},{"last_name":"Ma","first_name":"Qian","full_name":"Ma, Qian"},{"first_name":"Heyuan","last_name":"Zhu","full_name":"Zhu, Heyuan"},{"full_name":"Janssens, Hilde","last_name":"Janssens","first_name":"Hilde"},{"last_name":"Vukašinović","first_name":"Nemanja","full_name":"Vukašinović, Nemanja"},{"last_name":"Kvasnica","first_name":"Miroslav","full_name":"Kvasnica, Miroslav"},{"full_name":"Winne, Johan M.","last_name":"Winne","first_name":"Johan M."},{"last_name":"Gao","first_name":"Yongxiang","full_name":"Gao, Yongxiang"},{"orcid":"0000-0002-0471-8285","first_name":"Shutang","last_name":"Tan","full_name":"Tan, Shutang","id":"2DE75584-F248-11E8-B48F-1D18A9856A87"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří","orcid":"0000-0002-8302-7596"},{"full_name":"Liu, Xin","first_name":"Xin","last_name":"Liu"},{"full_name":"Russinova, Eugenia","first_name":"Eugenia","last_name":"Russinova"},{"full_name":"Sun, Linfeng","last_name":"Sun","first_name":"Linfeng"}],"OA_type":"green","OA_place":"repository","intvolume":"       383","date_updated":"2025-09-04T13:19:48Z","language":[{"iso":"eng"}],"article_type":"original","citation":{"chicago":"Ying, Wei, Yaowei Wang, Hong Wei, Yongming Luo, Qian Ma, Heyuan Zhu, Hilde Janssens, et al. “Structure and Function of the Arabidopsis ABC Transporter ABCB19 in Brassinosteroid Export.” <i>Science</i>. American Association for the Advancement of Science, 2024. <a href=\"https://doi.org/10.1126/science.adj4591\">https://doi.org/10.1126/science.adj4591</a>.","apa":"Ying, W., Wang, Y., Wei, H., Luo, Y., Ma, Q., Zhu, H., … Sun, L. (2024). Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.adj4591\">https://doi.org/10.1126/science.adj4591</a>","ieee":"W. Ying <i>et al.</i>, “Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export,” <i>Science</i>, vol. 383, no. 6689. American Association for the Advancement of Science, p. eadj4591, 2024.","ista":"Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukašinović N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L. 2024. Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. Science. 383(6689), eadj4591.","ama":"Ying W, Wang Y, Wei H, et al. Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. <i>Science</i>. 2024;383(6689):eadj4591. doi:<a href=\"https://doi.org/10.1126/science.adj4591\">10.1126/science.adj4591</a>","mla":"Ying, Wei, et al. “Structure and Function of the Arabidopsis ABC Transporter ABCB19 in Brassinosteroid Export.” <i>Science</i>, vol. 383, no. 6689, American Association for the Advancement of Science, 2024, p. eadj4591, doi:<a href=\"https://doi.org/10.1126/science.adj4591\">10.1126/science.adj4591</a>.","short":"W. Ying, Y. Wang, H. Wei, Y. Luo, Q. Ma, H. Zhu, H. Janssens, N. Vukašinović, M. Kvasnica, J.M. Winne, Y. Gao, S. Tan, J. Friml, X. Liu, E. Russinova, L. Sun, Science 383 (2024) eadj4591."},"type":"journal_article","main_file_link":[{"url":"http://hdl.handle.net/1854/LU-01HTMBK3P3PPNB73YFCMFXP3ZZ","open_access":"1"}],"publication":"Science","oa_version":"Submitted Version","date_created":"2024-03-31T22:01:12Z","scopus_import":"1","external_id":{"pmid":["38513023"],"isi":["001252955200028"]},"status":"public","abstract":[{"text":"Brassinosteroids are steroidal phytohormones that regulate plant development and physiology, including adaptation to environmental stresses. Brassinosteroids are synthesized in the cell interior but bind receptors at the cell surface, necessitating a yet to be identified export mechanism. Here, we show that a member of the ATP-binding cassette (ABC) transporter superfamily, ABCB19, functions as a brassinosteroid exporter. We present its structure in both the substrate-unbound and the brassinosteroid-bound states. Bioactive brassinosteroids are potent activators of ABCB19 ATP hydrolysis activity, and transport assays showed that ABCB19 transports brassinosteroids. In Arabidopsis thaliana, ABCB19 and its close homolog, ABCB1, positively regulate brassinosteroid responses. Our results uncover an elusive export mechanism for bioactive brassinosteroids that is tightly coordinated with brassinosteroid signaling.","lang":"eng"}],"day":"22","department":[{"_id":"JiFr"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export","oa":1,"article_processing_charge":"No","publication_identifier":{"eissn":["1095-9203"]},"isi":1,"acknowledgement":"We thank the Cryo-EM Center of the University of Science and Technology of China for the EM facility support, Y. Yin (Iowa State University, Ames, IA, USA) for providing the anti-BES1 antibody, Y. Gao and all other staff members for their technical support on cryo-EM data collection, S. Vanneste (VIB, Ghent University, Ghent, Belgium) for useful discussions, and M. De Cock for help in preparing the manuscript.\r\nThis work was supported by the National Natural Science Foundation of China (grants 31870732 and 32322041 to L.S., grant 31900885 to X.L., and grant 32321001 to L.S.); the Strategic Priority Research Program of the Chinese Academy of Sciences (grant XDB37020103 to L.S.); the Natural Science Foundation of Anhui Province (grant 2008085MC90 to X.L. and grant 2008085J15 to L.S.); Fundamental Research Funds for the Central Universities (grant WK9100000031 to L.S.); USTC Research Funds of the Double First-Class Initiative (grant YD9100002004 to L.S. and grant YD9100002020 to X.L.); Research Foundation-Flanders (grant G002121N to E.R. and postdoctoral fellowships 12R7822N and 12R7819N to N.V.); and Chinese Scholarship Council predoctoral fellowships (Y.W. and H.Z.). L.S. is supported by an Outstanding Young Scholar Award from the Qiu Shi Science and Technologies Foundation and a Young Scholar Award from the Cyrus Tang Foundation.","doi":"10.1126/science.adj4591","publisher":"American Association for the Advancement of Science","_id":"15251","quality_controlled":"1","date_published":"2024-03-22T00:00:00Z"},{"external_id":{"arxiv":["2304.11348"]},"status":"public","abstract":[{"lang":"eng","text":"A measurable map between measure spaces is shown to have bounded compression if and only if its image via the measure-algebra functor is Lipschitz-continuous w.r.t. the measure-algebra distances. This provides a natural interpretation of maps of bounded compression/deformation by means of the measure-algebra functor and corrobo-rates the assertion that maps of bounded deformation are a natural class of morphisms for the category of complete and separable metric measure spaces."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2304.11348"}],"type":"journal_article","corr_author":"1","date_created":"2024-03-31T22:01:12Z","publication":"Mathematical Communications","scopus_import":"1","oa_version":"Preprint","language":[{"iso":"eng"}],"citation":{"short":"L. Dello Schiavo, Mathematical Communications 29 (2024) 137–142.","mla":"Dello Schiavo, Lorenzo. “A Characterization of Maps of Bounded Compression.” <i>Mathematical Communications</i>, vol. 29, no. 1, Udruga Matematicara Osijek, 2024, pp. 137–42.","ista":"Dello Schiavo L. 2024. A characterization of maps of bounded compression. Mathematical Communications. 29(1), 137–142.","ama":"Dello Schiavo L. A characterization of maps of bounded compression. <i>Mathematical Communications</i>. 2024;29(1):137-142.","ieee":"L. Dello Schiavo, “A characterization of maps of bounded compression,” <i>Mathematical Communications</i>, vol. 29, no. 1. Udruga Matematicara Osijek, pp. 137–142, 2024.","apa":"Dello Schiavo, L. (2024). A characterization of maps of bounded compression. <i>Mathematical Communications</i>. Udruga Matematicara Osijek.","chicago":"Dello Schiavo, Lorenzo. “A Characterization of Maps of Bounded Compression.” <i>Mathematical Communications</i>. Udruga Matematicara Osijek, 2024."},"article_type":"original","arxiv":1,"date_updated":"2025-04-14T12:59:08Z","intvolume":"        29","project":[{"name":"Configuration Spaces over Non-Smooth Spaces","_id":"34dbf174-11ca-11ed-8bc3-afe9d43d4b9c","grant_number":"E208"}],"author":[{"full_name":"Dello Schiavo, Lorenzo","id":"ECEBF480-9E4F-11EA-B557-B0823DDC885E","last_name":"Dello Schiavo","orcid":"0000-0002-9881-6870","first_name":"Lorenzo"}],"page":"137-142","publication_status":"published","year":"2024","month":"01","volume":29,"issue":"1","date_published":"2024-01-01T00:00:00Z","_id":"15252","quality_controlled":"1","publisher":"Udruga Matematicara Osijek","acknowledgement":"The author gratefully acknowledges funding of his current position by the Austrian Science\r\nFund (FWF), grant ESPRIT208. He is grateful to Enrico Pasqualetto for pointing out some\r\nreferences on maps of bounded compression.","publication_identifier":{"eissn":["1848-8013"],"issn":["1331-0623"]},"article_processing_charge":"No","title":"A characterization of maps of bounded compression","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"JaMa"}],"day":"01"},{"_id":"15253","date_published":"2024-01-04T00:00:00Z","quality_controlled":"1","publisher":"Society for Industrial and Applied Mathematics","doi":"10.1137/1.9781611977912.38","acknowledgement":"This  project  has  received  funding  from  the  European  Research  Council  (ERC)under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No.101019564 “The Design of Modern Fully Dynamic Data Structures (MoDynStruct)” and the AustrianScience Fund (FWF) project Z 422-N, project “Static and Dynamic Hierarchical Graph Decompositions”, I 5982-N, andproject “Fast Algorithms for a Reactive Network Layer (ReactNet)”, P 33775-N, with additional funding from the netideeSCIENCE  Stiftung,  2020–2024.   JU’s  research  was  funded  by  the  Decanal  Research  Grant.   We  thank  the  anonymousreviewers for their useful feedback and pointing us to the results in Matousek et al","conference":{"name":"SODA: Symposium on Discrete Algorithms","location":"Alexandria, VA, United States","start_date":"2024-01-07","end_date":"2024-01-10"},"publication_identifier":{"eisbn":["9781611977912"]},"article_processing_charge":"No","department":[{"_id":"MoHe"}],"day":"04","title":"A unifying framework for differentially private sums under continual observation","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"citation":{"chicago":"Henzinger, Monika, Jalaj Upadhyay, and Sarvagya Upadhyay. “A Unifying Framework for Differentially Private Sums under Continual Observation.” In <i>Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 2024:995–1018. Society for Industrial and Applied Mathematics, 2024. <a href=\"https://doi.org/10.1137/1.9781611977912.38\">https://doi.org/10.1137/1.9781611977912.38</a>.","mla":"Henzinger, Monika, et al. “A Unifying Framework for Differentially Private Sums under Continual Observation.” <i>Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, vol. 2024, Society for Industrial and Applied Mathematics, 2024, pp. 995–1018, doi:<a href=\"https://doi.org/10.1137/1.9781611977912.38\">10.1137/1.9781611977912.38</a>.","short":"M. Henzinger, J. Upadhyay, S. Upadhyay, in:, Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024, pp. 995–1018.","apa":"Henzinger, M., Upadhyay, J., &#38; Upadhyay, S. (2024). A unifying framework for differentially private sums under continual observation. In <i>Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms</i> (Vol. 2024, pp. 995–1018). Alexandria, VA, United States: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611977912.38\">https://doi.org/10.1137/1.9781611977912.38</a>","ama":"Henzinger M, Upadhyay J, Upadhyay S. A unifying framework for differentially private sums under continual observation. In: <i>Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Vol 2024. Society for Industrial and Applied Mathematics; 2024:995-1018. doi:<a href=\"https://doi.org/10.1137/1.9781611977912.38\">10.1137/1.9781611977912.38</a>","ieee":"M. Henzinger, J. Upadhyay, and S. Upadhyay, “A unifying framework for differentially private sums under continual observation,” in <i>Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Alexandria, VA, United States, 2024, vol. 2024, pp. 995–1018.","ista":"Henzinger M, Upadhyay J, Upadhyay S. 2024. A unifying framework for differentially private sums under continual observation. Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms vol. 2024, 995–1018."},"ec_funded":1,"status":"public","external_id":{"arxiv":["2307.08970"]},"abstract":[{"text":"We study the problem of maintaining a differentially private decaying sum under continual observation. We give a unifying framework and an efficient algorithm for this problem for any sufficiently smooth function. Our algorithm is the first differentially private algorithm that does not have a multiplicative error for polynomially decaying weights. Our algorithm improves on all prior works on differentially private decaying sums under continual observation and recovers exactly the additive error for the special case of continual counting from Henzinger et al. (SODA 2023) as a corollary.\r\nOur algorithm is a variant of the matrix mechanism whose error depends on the γ2 and γF norm of the underlying matrix. We give a constructive proof for an almost exact upper bound on the γ2 and γF norm and an almost tight lower bound on the γ2 norm for a large class of lower-triangular matrices. This is the first non-trivial lower bound for lower-triangular matrices whose non-zero entries are not all the same. It includes matrices for all continual decaying sums problems, resulting in an upper bound on the additive error of any differentially private decaying sums algorithm under continual observation.\r\nWe also explore some implications of our result in discrepancy theory and operator algebra. Given the importance of the γ2 norm in computer science and the extensive work in mathematics, we believe our result will have further applications.","lang":"eng"}],"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2307.08970","open_access":"1"}],"type":"conference","corr_author":"1","oa_version":"Preprint","date_created":"2024-03-31T22:01:13Z","scopus_import":"1","publication":"Proceedings of the 2024 Annual ACM-SIAM Symposium on Discrete Algorithms","project":[{"grant_number":"101019564","name":"The design and evaluation of modern fully dynamic data structures","call_identifier":"H2020","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62"},{"grant_number":"Z00422","_id":"34def286-11ca-11ed-8bc3-da5948e1613c","name":"Efficient algorithms"},{"grant_number":"I05982","_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103","name":"Static and Dynamic Hierarchical Graph Decompositions"},{"grant_number":"P33775","name":"Fast Algorithms for a Reactive Network Layer","_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe"}],"arxiv":1,"date_updated":"2025-04-14T13:50:49Z","intvolume":"      2024","page":"995-1018","author":[{"id":"540c9bbd-f2de-11ec-812d-d04a5be85630","full_name":"Henzinger, Monika H","last_name":"Henzinger","first_name":"Monika H","orcid":"0000-0002-5008-6530"},{"full_name":"Upadhyay, Jalaj","first_name":"Jalaj","last_name":"Upadhyay"},{"last_name":"Upadhyay","first_name":"Sarvagya","full_name":"Upadhyay, Sarvagya"}],"month":"01","volume":2024,"publication_status":"published","year":"2024"},{"article_type":"original","ec_funded":1,"citation":{"apa":"Kulich, I., Schmid, J., Teplova, A., Qi, L., &#38; Friml, J. (2024). Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/elife.91523\">https://doi.org/10.7554/elife.91523</a>","ista":"Kulich I, Schmid J, Teplova A, Qi L, Friml J. 2024. Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism. eLife. 12, 91523.","ama":"Kulich I, Schmid J, Teplova A, Qi L, Friml J. Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism. <i>eLife</i>. 2024;12. doi:<a href=\"https://doi.org/10.7554/elife.91523\">10.7554/elife.91523</a>","ieee":"I. Kulich, J. Schmid, A. Teplova, L. Qi, and J. Friml, “Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism,” <i>eLife</i>, vol. 12. eLife Sciences Publications, 2024.","mla":"Kulich, Ivan, et al. “Rapid Translocation of NGR Proteins Driving Polarization of PIN-Activating D6 Protein Kinase during Root Gravitropism.” <i>ELife</i>, vol. 12, 91523, eLife Sciences Publications, 2024, doi:<a href=\"https://doi.org/10.7554/elife.91523\">10.7554/elife.91523</a>.","short":"I. Kulich, J. Schmid, A. Teplova, L. Qi, J. Friml, ELife 12 (2024).","chicago":"Kulich, Ivan, Julia Schmid, Anastasiia Teplova, Linlin Qi, and Jiří Friml. “Rapid Translocation of NGR Proteins Driving Polarization of PIN-Activating D6 Protein Kinase during Root Gravitropism.” <i>ELife</i>. eLife Sciences Publications, 2024. <a href=\"https://doi.org/10.7554/elife.91523\">https://doi.org/10.7554/elife.91523</a>."},"DOAJ_listed":"1","language":[{"iso":"eng"}],"oa_version":"Published Version","publication":"eLife","date_created":"2024-04-02T11:35:58Z","scopus_import":"1","corr_author":"1","type":"journal_article","abstract":[{"text":"Root gravitropic bending represents a fundamental aspect of terrestrial plant physiology. Gravity is perceived by sedimentation of starch-rich plastids (statoliths) to the bottom of the central root cap cells. Following gravity perception, intercellular auxin transport is redirected downwards leading to an asymmetric auxin accumulation at the lower root side causing inhibition of cell expansion, ultimately resulting in downwards bending. How gravity-induced statoliths repositioning is translated into asymmetric auxin distribution remains unclear despite PIN auxin efflux carriers and the Negative Gravitropic Response of roots (NGR) proteins polarize along statolith sedimentation, thus providing a plausible mechanism for auxin flow redirection. In this study, using a functional NGR1-GFP construct, we visualized the NGR1 localization on the statolith surface and plasma membrane (PM) domains in close proximity to the statoliths, correlating with their movements. We determined that NGR1 binding to these PM domains is indispensable for NGR1 functionality and relies on cysteine acylation and adjacent polybasic regions as well as on lipid and sterol PM composition. Detailed timing of the early events following graviperception suggested that both NGR1 repolarization and initial auxin asymmetry precede the visible PIN3 polarization. This discrepancy motivated us to unveil a rapid, NGR-dependent translocation of PIN-activating AGCVIII kinase D6PK towards lower PMs of gravity-perceiving cells, thus providing an attractive model for rapid redirection of auxin fluxes following gravistimulation.","lang":"eng"}],"has_accepted_license":"1","status":"public","external_id":{"pmid":["38441122"]},"project":[{"grant_number":"742985","_id":"261099A6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants"},{"call_identifier":"FWF","_id":"26538374-B435-11E9-9278-68D0E5697425","name":"Molecular mechanisms of endocytic cargo recognition in plants","grant_number":"I03630"}],"intvolume":"        12","date_updated":"2025-04-23T07:45:02Z","ddc":["580"],"pmid":1,"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"author":[{"full_name":"Kulich, Ivan","id":"57a1567c-8314-11eb-9063-c9ddc3451a54","first_name":"Ivan","last_name":"Kulich"},{"last_name":"Schmid","first_name":"Julia","full_name":"Schmid, Julia","id":"07cf4637-baaf-11ee-9227-e1de57d1d69b"},{"id":"e3736151-106c-11ec-b916-c2558e2762c6","full_name":"Teplova, Anastasiia","last_name":"Teplova","first_name":"Anastasiia"},{"last_name":"Qi","first_name":"Linlin","orcid":"0000-0001-5187-8401","id":"44B04502-A9ED-11E9-B6FC-583AE6697425","full_name":"Qi, Linlin"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří","orcid":"0000-0002-8302-7596"}],"related_material":{"link":[{"description":"News on ISTA website","relation":"press_release","url":"https://ista.ac.at/en/news/beneath-the-surface/"}]},"volume":12,"month":"03","year":"2024","file_date_updated":"2024-04-03T13:18:00Z","publication_status":"published","date_published":"2024-03-05T00:00:00Z","_id":"15257","quality_controlled":"1","article_number":"91523","file":[{"creator":"dernst","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2024-04-03T13:18:00Z","file_size":11451904,"checksum":"a73a84d3bf97a6d09d24308ca6dd0a0c","success":1,"file_name":"2024_eLife_Kulich.pdf","file_id":"15288","date_updated":"2024-04-03T13:18:00Z"}],"doi":"10.7554/elife.91523","acknowledgement":"The research leading to these results has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme grant agreement No 742985 and Austrian Science Fund (FWF): I3630-775 B25 to J.F. This research was also supported by the Lab Support Facility (LSF) and the Imaging and Optics Facility (IOF) of IST Austria, namely Tereza Bělinová for her help with the imaging. JS was supported by FemTECH fellowship.","publisher":"eLife Sciences Publications","article_processing_charge":"Yes","publication_identifier":{"issn":["2050-084X"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"day":"05","keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","General Medicine","General Neuroscience"],"department":[{"_id":"JiFr"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"title":"Rapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism"},{"day":"01","department":[{"_id":"TiVo"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa":1,"title":"Ten simple rules for pushing boundaries of inclusion at academic events","article_processing_charge":"Yes","publication_identifier":{"issn":["1553-7358"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"acknowledgement":"We would like to recognise the feedback and ideas shared with us by all attendees during the\r\nfocus groups that contributed to the development of this paper. Acknowledgements are given\r\nto Elisee Jafsia, Umar Farouk Ahmad, Zohra Slim, Mizanur Rahman, Rev. Katie Tupling,\r\nChristopher Emmanuel, Abdalrhman Mostafa, Pradeep Eranti, Toby Hodges, Avishkar\r\nBhoopchand, and Carolyn Dickson. We would like to thank our community members and\r\nacknowledge their bravery for sharing their stories that shaped the narrative of these Ten Simple\r\nRules. The stories shared with us formed the case studies, and while they are anonymous\r\nfor privacy and protection reasons, it is these stories that were on our mind during the entire\r\nprocess and kept us going. We acknowledge the efforts of the organisers that contribute to the\r\nhighly successful events that are the inspiration for the ideas presented here: the Deep\r\nLearning Indaba, Neuromatch Academy, the IBRO Simons Computational Neuroscience\r\nImbizo, and OLS. OLS also supported this project through their mentorship programme,\r\nOpen Seeds.","isi":1,"file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","content_type":"application/pdf","date_created":"2024-04-03T13:29:36Z","file_size":858521,"success":1,"checksum":"1f0f837c5b4341f54f6347370ed8c1b7","date_updated":"2024-04-03T13:29:36Z","file_id":"15289","file_name":"2024_PloS_Hall.pdf"}],"doi":"10.1371/journal.pcbi.1011797","publisher":"Public Library of Science","date_published":"2024-03-01T00:00:00Z","_id":"15258","quality_controlled":"1","article_number":"e1011797","issue":"3","volume":20,"month":"03","year":"2024","publication_status":"published","file_date_updated":"2024-04-03T13:29:36Z","pmid":1,"author":[{"full_name":"Hall, Siobhan Mackenzie","first_name":"Siobhan Mackenzie","last_name":"Hall"},{"last_name":"Kochin","first_name":"Daniel","full_name":"Kochin, Daniel"},{"first_name":"Carmel","last_name":"Carne","full_name":"Carne, Carmel"},{"full_name":"Herterich, Patricia","last_name":"Herterich","first_name":"Patricia"},{"first_name":"Kristen Lenay","last_name":"Lewers","full_name":"Lewers, Kristen Lenay"},{"full_name":"Abdelhack, Mohamed","first_name":"Mohamed","last_name":"Abdelhack"},{"full_name":"Ramasubramanian, Arun","last_name":"Ramasubramanian","first_name":"Arun"},{"first_name":"Juno Felecia","last_name":"Michael Alphonse","full_name":"Michael Alphonse, Juno Felecia"},{"first_name":"Visotheary","last_name":"Ung","full_name":"Ung, Visotheary"},{"full_name":"El-Gebali, Sara","last_name":"El-Gebali","first_name":"Sara"},{"first_name":"Christopher","orcid":"0000-0002-4809-5059","last_name":"Currin","id":"e8321fc5-3091-11eb-8a53-83f309a11ac9","full_name":"Currin, Christopher"},{"full_name":"Plomp, Esther","last_name":"Plomp","first_name":"Esther"},{"last_name":"Thompson","first_name":"Rachel","full_name":"Thompson, Rachel"},{"first_name":"Malvika","last_name":"Sharan","full_name":"Sharan, Malvika"}],"OA_type":"gold","OA_place":"publisher","intvolume":"        20","date_updated":"2025-09-04T13:24:19Z","ddc":["000"],"DOAJ_listed":"1","citation":{"mla":"Hall, Siobhan Mackenzie, et al. “Ten Simple Rules for Pushing Boundaries of Inclusion at Academic Events.” <i>PLOS Computational Biology</i>, vol. 20, no. 3, e1011797, Public Library of Science, 2024, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1011797\">10.1371/journal.pcbi.1011797</a>.","short":"S.M. Hall, D. Kochin, C. Carne, P. Herterich, K.L. Lewers, M. Abdelhack, A. Ramasubramanian, J.F. Michael Alphonse, V. Ung, S. El-Gebali, C. Currin, E. Plomp, R. Thompson, M. Sharan, PLOS Computational Biology 20 (2024).","apa":"Hall, S. M., Kochin, D., Carne, C., Herterich, P., Lewers, K. L., Abdelhack, M., … Sharan, M. (2024). Ten simple rules for pushing boundaries of inclusion at academic events. <i>PLOS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1011797\">https://doi.org/10.1371/journal.pcbi.1011797</a>","ama":"Hall SM, Kochin D, Carne C, et al. Ten simple rules for pushing boundaries of inclusion at academic events. <i>PLOS Computational Biology</i>. 2024;20(3). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1011797\">10.1371/journal.pcbi.1011797</a>","ieee":"S. M. Hall <i>et al.</i>, “Ten simple rules for pushing boundaries of inclusion at academic events,” <i>PLOS Computational Biology</i>, vol. 20, no. 3. Public Library of Science, 2024.","ista":"Hall SM, Kochin D, Carne C, Herterich P, Lewers KL, Abdelhack M, Ramasubramanian A, Michael Alphonse JF, Ung V, El-Gebali S, Currin C, Plomp E, Thompson R, Sharan M. 2024. Ten simple rules for pushing boundaries of inclusion at academic events. PLOS Computational Biology. 20(3), e1011797.","chicago":"Hall, Siobhan Mackenzie, Daniel Kochin, Carmel Carne, Patricia Herterich, Kristen Lenay Lewers, Mohamed Abdelhack, Arun Ramasubramanian, et al. “Ten Simple Rules for Pushing Boundaries of Inclusion at Academic Events.” <i>PLOS Computational Biology</i>. Public Library of Science, 2024. <a href=\"https://doi.org/10.1371/journal.pcbi.1011797\">https://doi.org/10.1371/journal.pcbi.1011797</a>."},"article_type":"original","language":[{"iso":"eng"}],"scopus_import":"1","publication":"PLOS Computational Biology","oa_version":"Published Version","date_created":"2024-04-02T11:37:32Z","type":"journal_article","abstract":[{"lang":"eng","text":"Inclusion at academic events is facing increased scrutiny as the communities these events serve raise their expectations for who can practically attend. Active efforts in recent years to bring more diversity to academic events have brought progress and created momentum. However, we must reflect on these efforts and determine which underrepresented groups are being disadvantaged. Inclusion at academic events is important to ensure diversity of discourse and opinion, to help build networks, and to avoid academic siloing. All of these contribute to the development of a robust and resilient academic field. We have developed these Ten Simple Rules both to amplify the voices that have been speaking out and to celebrate the progress of many Equity, Diversity, and Inclusivity practices that continue to drive the organisation of academic events. The Rules aim to raise awareness as well as provide actionable suggestions and tools to support these initiatives further. This aims to support academic organisations such as the Deep Learning Indaba, Neuromatch Academy, the IBRO-Simons Computational Neuroscience Imbizo, Biodiversity Information Standards (TDWG), Arabs in Neuroscience, FAIRPoints, and OLS (formerly Open Life Science). This article is a call to action for organisers to reevaluate the impact and reach of their inclusive practices."}],"external_id":{"pmid":["38427633"],"isi":["001181690200005"]},"has_accepted_license":"1","status":"public"},{"article_processing_charge":"Yes","publication_identifier":{"issn":["0010-440X"],"eissn":["1532-8384"]},"tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"day":"01","department":[{"_id":"TiVo"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa":1,"title":"Meta-analysis of the comparative efficacy of benzodiazepines and antidepressants for psychic versus somatic symptoms of generalized anxiety disorder","date_published":"2024-07-01T00:00:00Z","_id":"15295","quality_controlled":"1","article_number":"152479","doi":"10.1016/j.comppsych.2024.152479","isi":1,"file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","date_created":"2025-01-13T10:47:20Z","content_type":"application/pdf","file_size":2874425,"checksum":"aadb57448b5f170761ed72cbcc31ba16","success":1,"date_updated":"2025-01-13T10:47:20Z","file_name":"2024_ComprehensivePsychiatry_Beyer.pdf","file_id":"18839"}],"publisher":"Elsevier","pmid":1,"author":[{"last_name":"Beyer","first_name":"Chad","full_name":"Beyer, Chad"},{"full_name":"Currin, Christopher","id":"e8321fc5-3091-11eb-8a53-83f309a11ac9","orcid":"0000-0002-4809-5059","first_name":"Christopher","last_name":"Currin"},{"full_name":"Williams, Taryn","first_name":"Taryn","last_name":"Williams"},{"full_name":"Stein, Dan J.","first_name":"Dan J.","last_name":"Stein"}],"volume":132,"month":"07","year":"2024","publication_status":"published","file_date_updated":"2025-01-13T10:47:20Z","citation":{"chicago":"Beyer, Chad, Christopher Currin, Taryn Williams, and Dan J. Stein. “Meta-Analysis of the Comparative Efficacy of Benzodiazepines and Antidepressants for Psychic versus Somatic Symptoms of Generalized Anxiety Disorder.” <i>Comprehensive Psychiatry</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.comppsych.2024.152479\">https://doi.org/10.1016/j.comppsych.2024.152479</a>.","apa":"Beyer, C., Currin, C., Williams, T., &#38; Stein, D. J. (2024). Meta-analysis of the comparative efficacy of benzodiazepines and antidepressants for psychic versus somatic symptoms of generalized anxiety disorder. <i>Comprehensive Psychiatry</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.comppsych.2024.152479\">https://doi.org/10.1016/j.comppsych.2024.152479</a>","ieee":"C. Beyer, C. Currin, T. Williams, and D. J. Stein, “Meta-analysis of the comparative efficacy of benzodiazepines and antidepressants for psychic versus somatic symptoms of generalized anxiety disorder,” <i>Comprehensive Psychiatry</i>, vol. 132. Elsevier, 2024.","ista":"Beyer C, Currin C, Williams T, Stein DJ. 2024. Meta-analysis of the comparative efficacy of benzodiazepines and antidepressants for psychic versus somatic symptoms of generalized anxiety disorder. Comprehensive Psychiatry. 132, 152479.","ama":"Beyer C, Currin C, Williams T, Stein DJ. Meta-analysis of the comparative efficacy of benzodiazepines and antidepressants for psychic versus somatic symptoms of generalized anxiety disorder. <i>Comprehensive Psychiatry</i>. 2024;132. doi:<a href=\"https://doi.org/10.1016/j.comppsych.2024.152479\">10.1016/j.comppsych.2024.152479</a>","mla":"Beyer, Chad, et al. “Meta-Analysis of the Comparative Efficacy of Benzodiazepines and Antidepressants for Psychic versus Somatic Symptoms of Generalized Anxiety Disorder.” <i>Comprehensive Psychiatry</i>, vol. 132, 152479, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.comppsych.2024.152479\">10.1016/j.comppsych.2024.152479</a>.","short":"C. Beyer, C. Currin, T. Williams, D.J. Stein, Comprehensive Psychiatry 132 (2024)."},"DOAJ_listed":"1","article_type":"original","language":[{"iso":"eng"}],"publication":"Comprehensive Psychiatry","scopus_import":"1","oa_version":"Published Version","date_created":"2024-04-07T22:00:55Z","type":"journal_article","abstract":[{"text":"Background: Benzodiazepines and antidepressants are effective agents for the treatment of generalized anxiety disorder (GAD), with the HAM-A frequently used as a primary outcome measure. The GAD literature is inconsistent regarding which medications are more effective for somatic versus psychic symptoms of GAD, and treatment guidelines do not advocate for prescribing based on subtype. This meta-analysis aimed to determine whether benzodiazepines and antidepressants have a differential impact on the somatic versus psychic subscales of the HAM-A in GAD.\r\n\r\nMethods: An electronic search was undertaken for randomized controlled trials of either benzodiazepines or antidepressants for GAD that reported treatment response using the HAM-A subscales. Data were extracted by independent reviewers. A random effects assessment of weighted mean difference with 95% confidence intervals and subgroup difference was applied. All analysis was done on SPSS 26. An assessment of bias, and of quality of evidence was performed.\r\n\r\nResults: 24 randomized controlled trials met the inclusion criteria: 18 antidepressant trials, 5 benzodiazepine trials and 1 of both. 14 studies were assessed as having between some and high risk of bias, while 10 were assessed as having low risk of bias. Benzodiazepines (WMD of 1.81 [CI 1.03, 2.58]) were significantly more effective than antidepressants (WMD of 0.83 [CI 0.64, 1.02]) for reducing somatic symptoms of GAD (Chi2 = 5.81, p = 0.02), and were also more effective (WMD of 2.46 [CI 1.83, 3.09]) in reducing psychic symptoms than antidepressants (WMD of 1.83 [CI 1.55, 2.10]), although this comparison did not reach statistical significance (Chi2 = 3.31, p = 0.07).\r\n\r\nConclusion: The finding that benzodiazepines were significantly more effective than antidepressants for somatic symptoms needs to be weighed up against potential benefits of antidepressants over benzodiazepines. It may be useful for future treatment guidelines for GAD to explicitly consider symptom subtype.","lang":"eng"}],"external_id":{"pmid":["38564872"],"isi":["001221136000001"]},"status":"public","has_accepted_license":"1","OA_type":"gold","intvolume":"       132","date_updated":"2025-09-04T13:30:08Z","ddc":["570"]}]