[{"date_published":"2023-10-20T00:00:00Z","intvolume":" 26","day":"20","quality_controlled":"1","publication_identifier":{"eissn":["2589-0042"]},"article_processing_charge":"Yes","department":[{"_id":"SaSi"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Maes, Margaret E., et al. “Mitochondrial Network Adaptations of Microglia Reveal Sex-Specific Stress Response after Injury and UCP2 Knockout.” IScience, vol. 26, no. 10, 107780, Elsevier, 2023, doi:10.1016/j.isci.2023.107780.","ista":"Maes ME, Colombo G, Schoot Uiterkamp FE, Sternberg F, Venturino A, Pohl EE, Siegert S. 2023. Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout. iScience. 26(10), 107780.","apa":"Maes, M. E., Colombo, G., Schoot Uiterkamp, F. E., Sternberg, F., Venturino, A., Pohl, E. E., & Siegert, S. (2023). Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout. IScience. Elsevier. https://doi.org/10.1016/j.isci.2023.107780","chicago":"Maes, Margaret E, Gloria Colombo, Florianne E Schoot Uiterkamp, Felix Sternberg, Alessandro Venturino, Elena E. Pohl, and Sandra Siegert. “Mitochondrial Network Adaptations of Microglia Reveal Sex-Specific Stress Response after Injury and UCP2 Knockout.” IScience. Elsevier, 2023. https://doi.org/10.1016/j.isci.2023.107780.","ieee":"M. E. Maes et al., “Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout,” iScience, vol. 26, no. 10. Elsevier, 2023.","ama":"Maes ME, Colombo G, Schoot Uiterkamp FE, et al. Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout. iScience. 2023;26(10). doi:10.1016/j.isci.2023.107780","short":"M.E. Maes, G. Colombo, F.E. Schoot Uiterkamp, F. Sternberg, A. Venturino, E.E. Pohl, S. Siegert, IScience 26 (2023)."},"issue":"10","publisher":"Elsevier","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"corr_author":"1","has_accepted_license":"1","acknowledgement":"We thank the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging and Optics Facility (IOF), the Lab Support Facility (LSF), and the Pre-Clinical Facility (PCF) team, specifically Sonja Haslinger and Michael Schunn for excellent mouse colony management and support. This research was supported by the FWF Sonderforschungsbereich F83 (to E.E.P). We thank Bálint Nagy, Ryan John A. Cubero, Marco Benevento and all members of the Siegert group for constant feedback on the project and article.","article_number":"107780","license":"https://creativecommons.org/licenses/by/4.0/","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"oa":1,"doi":"10.1016/j.isci.2023.107780","file_date_updated":"2023-11-07T08:53:21Z","pmid":1,"type":"journal_article","month":"10","author":[{"first_name":"Margaret E","orcid":"0000-0001-9642-1085","full_name":"Maes, Margaret E","id":"3838F452-F248-11E8-B48F-1D18A9856A87","last_name":"Maes"},{"full_name":"Colombo, Gloria","orcid":"0000-0001-9434-8902","first_name":"Gloria","last_name":"Colombo","id":"3483CF6C-F248-11E8-B48F-1D18A9856A87"},{"id":"3526230C-F248-11E8-B48F-1D18A9856A87","last_name":"Schoot Uiterkamp","first_name":"Florianne E","full_name":"Schoot Uiterkamp, Florianne E"},{"last_name":"Sternberg","full_name":"Sternberg, Felix","first_name":"Felix"},{"last_name":"Venturino","id":"41CB84B2-F248-11E8-B48F-1D18A9856A87","full_name":"Venturino, Alessandro","orcid":"0000-0003-2356-9403","first_name":"Alessandro"},{"full_name":"Pohl, Elena E.","first_name":"Elena E.","last_name":"Pohl"},{"full_name":"Siegert, Sandra","first_name":"Sandra","orcid":"0000-0001-8635-0877","id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","last_name":"Siegert"}],"ddc":["570"],"date_updated":"2024-10-09T21:07:01Z","publication_status":"published","article_type":"original","title":"Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout","status":"public","scopus_import":"1","file":[{"creator":"dernst","file_id":"14497","file_name":"2023_iScience_Maes.pdf","content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"be1a560efdd96d20712311f4fc54aac2","file_size":8197935,"date_updated":"2023-11-07T08:53:21Z","success":1,"date_created":"2023-11-07T08:53:21Z"}],"_id":"14363","language":[{"iso":"eng"}],"publication":"iScience","oa_version":"Published Version","external_id":{"pmid":["37731609"],"isi":["001080403500001"]},"date_created":"2023-09-24T22:01:11Z","isi":1,"volume":26,"year":"2023","abstract":[{"lang":"eng","text":"Mitochondrial networks remodel their connectivity, content, and subcellular localization to support optimized energy production in conditions of increased environmental or cellular stress. Microglia rely on mitochondria to respond to these stressors, however our knowledge about mitochondrial networks and their adaptations in microglia in vivo is limited. Here, we generate a mouse model that selectively labels mitochondria in microglia. We identify that mitochondrial networks are more fragmented with increased content and perinuclear localization in vitro vs. in vivo. Mitochondrial networks adapt similarly in microglia closest to the injury site after optic nerve crush. Preventing microglial UCP2 increase after injury by selective knockout induces cellular stress. This results in mitochondrial hyperfusion in male microglia, a phenotype absent in females due to circulating estrogens. Our results establish the foundation for mitochondrial network analysis of microglia in vivo, emphasizing the importance of mitochondrial-based sex effects of microglia in other pathologies."}]},{"external_id":{"isi":["001082972300004"],"arxiv":["1811.01421"]},"date_created":"2023-09-24T22:01:11Z","related_material":{"record":[{"id":"6676","relation":"earlier_version","status":"public"}]},"oa_version":"Preprint","abstract":[{"text":"We introduce extension-based proofs, a class of impossibility proofs that includes valency arguments. They are modelled as an interaction between a prover and a protocol. Using proofs based on combinatorial topology, it has been shown that it is impossible to deterministically solve -set agreement among processes or approximate agreement on a cycle of length 4 among processes in a wait-free manner in asynchronous models where processes communicate using objects that can be constructed from shared registers. However, it was unknown whether proofs based on simpler techniques were possible. We show that these impossibility results cannot be obtained by extension-based proofs in the iterated snapshot model and, hence, extension-based proofs are limited in power.","lang":"eng"}],"ec_funded":1,"page":"913-944","year":"2023","project":[{"grant_number":"805223","call_identifier":"H2020","name":"Elastic Coordination for Scalable Machine Learning","_id":"268A44D6-B435-11E9-9278-68D0E5697425"}],"volume":52,"isi":1,"publication_status":"published","date_updated":"2025-05-14T11:26:06Z","month":"07","author":[{"full_name":"Alistarh, Dan-Adrian","orcid":"0000-0003-3650-940X","first_name":"Dan-Adrian","last_name":"Alistarh","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Aspnes","full_name":"Aspnes, James","first_name":"James"},{"first_name":"Faith","full_name":"Ellen, Faith","last_name":"Ellen"},{"last_name":"Gelashvili","first_name":"Rati","full_name":"Gelashvili, Rati"},{"full_name":"Zhu, Leqi","first_name":"Leqi","id":"a2117c59-cee4-11ed-b9d0-874ecf0f8ac5","last_name":"Zhu"}],"_id":"14364","language":[{"iso":"eng"}],"publication":"SIAM Journal on Computing","article_type":"original","status":"public","scopus_import":"1","title":"Why extension-based proofs fail","acknowledgement":"We would like to thank Valerie King, Toniann Pitassi, and Michael Saks for helpful discussions and Shi Hao Liu for his useful feedback.\r\nThis research was supported by the Natural Science and Engineering Research Council of Canada under grants RGPIN-2015-05080 and RGPIN-2020-04178, a postgraduate scholarship, and a postdoctoral fellowship; a University of Toronto postdoctoral fellowship; the National Science Foundation under grants CCF-1217921, CCF-1301926, CCF-1637385, CCF-1650596, and IIS-1447786; the U.S. Department of Energy under grant ER26116/DE-SC0008923; the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme grant agreement 805223 ScaleML; and the Oracle and Intel corporations. Some of the work on this paper was done while Faith Ellen was visiting IST Austria.","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1811.01421"}],"type":"journal_article","oa":1,"doi":"10.1137/20M1375851","arxiv":1,"day":"25","quality_controlled":"1","date_published":"2023-07-25T00:00:00Z","intvolume":" 52","issue":"4","publisher":"Society for Industrial and Applied Mathematics","department":[{"_id":"DaAl"}],"citation":{"mla":"Alistarh, Dan-Adrian, et al. “Why Extension-Based Proofs Fail.” SIAM Journal on Computing, vol. 52, no. 4, Society for Industrial and Applied Mathematics, 2023, pp. 913–44, doi:10.1137/20M1375851.","ista":"Alistarh D-A, Aspnes J, Ellen F, Gelashvili R, Zhu L. 2023. Why extension-based proofs fail. SIAM Journal on Computing. 52(4), 913–944.","ieee":"D.-A. Alistarh, J. Aspnes, F. Ellen, R. Gelashvili, and L. Zhu, “Why extension-based proofs fail,” SIAM Journal on Computing, vol. 52, no. 4. Society for Industrial and Applied Mathematics, pp. 913–944, 2023.","apa":"Alistarh, D.-A., Aspnes, J., Ellen, F., Gelashvili, R., & Zhu, L. (2023). Why extension-based proofs fail. SIAM Journal on Computing. Society for Industrial and Applied Mathematics. https://doi.org/10.1137/20M1375851","chicago":"Alistarh, Dan-Adrian, James Aspnes, Faith Ellen, Rati Gelashvili, and Leqi Zhu. “Why Extension-Based Proofs Fail.” SIAM Journal on Computing. Society for Industrial and Applied Mathematics, 2023. https://doi.org/10.1137/20M1375851.","ama":"Alistarh D-A, Aspnes J, Ellen F, Gelashvili R, Zhu L. Why extension-based proofs fail. SIAM Journal on Computing. 2023;52(4):913-944. doi:10.1137/20M1375851","short":"D.-A. Alistarh, J. Aspnes, F. Ellen, R. Gelashvili, L. Zhu, SIAM Journal on Computing 52 (2023) 913–944."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1095-7111"],"issn":["0097-5397"]},"article_processing_charge":"No"},{"corr_author":"1","has_accepted_license":"1","acknowledgement":"We thank Dr. Kari Alitalo (University of Helsinki and Wihuri Research Institute) for critical reading of the manuscript, providing Vegfc+/− and Clp24ΔEC mouse strains and for hosting K.V.’s Academy of Finland postdoctoral researcher period (2015–2018). We thank Dr. Sara Wickström (University of Helsinki and Wihuri Research Institute) for providing Sox9:Egfp mouse\r\nstrain and the discussions. We thank Maija Atuegwu and Tapio Tainola for technical assistance. This work received funding from the Academy of Finland (K.V., 315710), Sigrid Juselius Foundation (K.V.), University of Helsinki (K.V.), Wihuri Research Institute (K.V.), the ERC under the European Union’s Horizon 2020 research and innovation program (grant agreement\r\nNo. 851288 to E.H.) and under the Marie Skłodowska-Curie grant agreement No. 754411 (to M.C.U.). Part of the work was carried out with the support of HiLIFE Laboratory Animal Centre Core Facility, University of Helsinki, Finland. Imaging was performed at the Biomedicum Imaging Unit, Helsinki University, Helsinki, Finland, with the support of Biocenter Finland. The AAVpreparations were produced at the Helsinki Virus (HelVi) Core.","article_number":"5878","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"oa":1,"doi":"10.1038/s41467-023-41456-7","file_date_updated":"2023-10-03T07:46:36Z","type":"journal_article","pmid":1,"date_published":"2023-09-21T00:00:00Z","intvolume":" 14","day":"21","quality_controlled":"1","publication_identifier":{"eissn":["2041-1723"]},"article_processing_charge":"Yes","citation":{"mla":"Ucar, Mehmet C., et al. “Self-Organized and Directed Branching Results in Optimal Coverage in Developing Dermal Lymphatic Networks.” Nature Communications, vol. 14, 5878, Springer Nature, 2023, doi:10.1038/s41467-023-41456-7.","chicago":"Ucar, Mehmet C, Edouard B Hannezo, Emmi Tiilikainen, Inam Liaqat, Emma Jakobsson, Harri Nurmi, and Kari Vaahtomeri. “Self-Organized and Directed Branching Results in Optimal Coverage in Developing Dermal Lymphatic Networks.” Nature Communications. Springer Nature, 2023. https://doi.org/10.1038/s41467-023-41456-7.","ieee":"M. C. Ucar et al., “Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks,” Nature Communications, vol. 14. Springer Nature, 2023.","apa":"Ucar, M. C., Hannezo, E. B., Tiilikainen, E., Liaqat, I., Jakobsson, E., Nurmi, H., & Vaahtomeri, K. (2023). Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-023-41456-7","ista":"Ucar MC, Hannezo EB, Tiilikainen E, Liaqat I, Jakobsson E, Nurmi H, Vaahtomeri K. 2023. Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks. Nature Communications. 14, 5878.","ama":"Ucar MC, Hannezo EB, Tiilikainen E, et al. Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks. Nature Communications. 2023;14. doi:10.1038/s41467-023-41456-7","short":"M.C. Ucar, E.B. Hannezo, E. Tiilikainen, I. Liaqat, E. Jakobsson, H. Nurmi, K. Vaahtomeri, Nature Communications 14 (2023)."},"department":[{"_id":"EdHa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Springer Nature","oa_version":"Published Version","date_created":"2023-10-01T22:01:13Z","external_id":{"pmid":["37735168"],"isi":["001075884500007"]},"project":[{"_id":"05943252-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020","name":"Design Principles of Branching Morphogenesis","grant_number":"851288"},{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships"}],"volume":14,"isi":1,"year":"2023","abstract":[{"lang":"eng","text":"Branching morphogenesis is a ubiquitous process that gives rise to high exchange surfaces in the vasculature and epithelial organs. Lymphatic capillaries form branched networks, which play a key role in the circulation of tissue fluid and immune cells. Although mouse models and correlative patient data indicate that the lymphatic capillary density directly correlates with functional output, i.e., tissue fluid drainage and trafficking efficiency of dendritic cells, the mechanisms ensuring efficient tissue coverage remain poorly understood. Here, we use the mouse ear pinna lymphatic vessel network as a model system and combine lineage-tracing, genetic perturbations, whole-organ reconstructions and theoretical modeling to show that the dermal lymphatic capillaries tile space in an optimal, space-filling manner. This coverage is achieved by two complementary mechanisms: initial tissue invasion provides a non-optimal global scaffold via self-organized branching morphogenesis, while VEGF-C dependent side-branching from existing capillaries rapidly optimizes local coverage by directionally targeting low-density regions. With these two ingredients, we show that a minimal biophysical model can reproduce quantitatively whole-network reconstructions, across development and perturbations. Our results show that lymphatic capillary networks can exploit local self-organizing mechanisms to achieve tissue-scale optimization."}],"ec_funded":1,"month":"09","author":[{"full_name":"Ucar, Mehmet C","orcid":"0000-0003-0506-4217","first_name":"Mehmet C","last_name":"Ucar","id":"50B2A802-6007-11E9-A42B-EB23E6697425"},{"full_name":"Hannezo, Edouard B","first_name":"Edouard B","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo"},{"last_name":"Tiilikainen","first_name":"Emmi","full_name":"Tiilikainen, Emmi"},{"last_name":"Liaqat","first_name":"Inam","full_name":"Liaqat, Inam"},{"last_name":"Jakobsson","first_name":"Emma","full_name":"Jakobsson, Emma"},{"first_name":"Harri","full_name":"Nurmi, Harri","last_name":"Nurmi"},{"id":"368EE576-F248-11E8-B48F-1D18A9856A87","last_name":"Vaahtomeri","full_name":"Vaahtomeri, Kari","first_name":"Kari","orcid":"0000-0001-7829-3518"}],"ddc":["570"],"date_updated":"2025-04-14T07:43:56Z","publication_status":"published","article_type":"original","title":"Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks","status":"public","file":[{"file_name":"2023_NatureComm_Ucar.pdf","access_level":"open_access","content_type":"application/pdf","relation":"main_file","creator":"dernst","file_id":"14384","date_updated":"2023-10-03T07:46:36Z","success":1,"date_created":"2023-10-03T07:46:36Z","checksum":"4fe5423403f2531753bcd9e0fea48e05","file_size":8143264}],"scopus_import":"1","_id":"14378","publication":"Nature Communications","language":[{"iso":"eng"}]},{"year":"2023","volume":299,"isi":1,"abstract":[{"text":"We report on a simple surfactant/template free chemical route for the synthesis of semi-polycrystalline polyaniline-graphite (SPani-graphite) composite and its application as an electroactive material in electrochemical charge storage. The synthesized material exhibits well-defined poly-crystallographic lattices in high resolution transmission electron micrographs and sharp peaks in x-ray diffraction spectra suggesting crystalline nature of the material. The specific capacitance computed from the galvanostatic charge-discharge (GCD) data obtained from 3-electrode cell configuration using 1 M aq. Na2SO4 as an electrolyte was 111.4 F g−1 at a current density of 0.1 A g−1 which rises to 269 F g−1 at an elevated current density of 1.0 A g−1. A similar pattern of increase in the specific capacitance values with an increase in the current density was observed in the results obtained from 2-electrode symmetric device configuration using polymer gel electrolyte (xanthan gum in 1 M aq. Na2SO4). The specific capacitance computed from the GCD data obtained from the device configuration was 20 F g−1 at the current density of 1.0 A g−1. The device delivers an energy density of 1.7 Wh kg−1 and a power density of 2.48 kWh kg−1 at an applied current density of 0.5 A g−1 suggesting an excellent rate capability and power management. In addition, the device exhibits ⁓92 % specific capacitance retention up to 8000 continuous GCD cycles and ⁓80 % coulombic efficiency up to 10,000 continuous GCD cycles indicating excellent cycling stability. The unique feature of increasing specific capacitance with respect to applied current density is attributed to the presence of semi-polycrystalline phases in the SPani-graphite matrix. The material behaves as a surface redox supercapacitor and its unique mechanism of charge storage is discussed in detail in the article.","lang":"eng"}],"oa_version":"None","date_created":"2023-10-01T22:01:13Z","external_id":{"isi":["001083568900001"]},"article_type":"original","scopus_import":"1","status":"public","title":"Polycrystalline phases grown in-situ engendering unique mechanism of charge storage in polyaniline-graphite composite","_id":"14379","language":[{"iso":"eng"}],"publication":"Synthetic Metals","month":"11","author":[{"first_name":"Neelima","full_name":"Mahato, Neelima","last_name":"Mahato"},{"first_name":"Saurabh","orcid":"0000-0003-2209-5269","full_name":"Singh, Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","last_name":"Singh"},{"last_name":"Faisal","first_name":"Mohammad","full_name":"Faisal, Mohammad"},{"full_name":"Sreekanth, T. V.M.","first_name":"T. V.M.","last_name":"Sreekanth"},{"last_name":"Majumder","first_name":"Sutripto","full_name":"Majumder, Sutripto"},{"full_name":"Yoo, Kisoo","first_name":"Kisoo","last_name":"Yoo"},{"full_name":"Kim, Jonghoon","first_name":"Jonghoon","last_name":"Kim"}],"publication_status":"published","date_updated":"2024-01-30T13:55:50Z","doi":"10.1016/j.synthmet.2023.117463","type":"journal_article","acknowledgement":"This work was supported by 2023 Yeungnam University Research Grant.","article_number":"117463","publication_identifier":{"issn":["0379-6779"]},"article_processing_charge":"No","publisher":"Elsevier","citation":{"ama":"Mahato N, Singh S, Faisal M, et al. Polycrystalline phases grown in-situ engendering unique mechanism of charge storage in polyaniline-graphite composite. Synthetic Metals. 2023;299. doi:10.1016/j.synthmet.2023.117463","short":"N. Mahato, S. Singh, M. Faisal, T.V.M. Sreekanth, S. Majumder, K. Yoo, J. Kim, Synthetic Metals 299 (2023).","mla":"Mahato, Neelima, et al. “Polycrystalline Phases Grown In-Situ Engendering Unique Mechanism of Charge Storage in Polyaniline-Graphite Composite.” Synthetic Metals, vol. 299, 117463, Elsevier, 2023, doi:10.1016/j.synthmet.2023.117463.","ieee":"N. Mahato et al., “Polycrystalline phases grown in-situ engendering unique mechanism of charge storage in polyaniline-graphite composite,” Synthetic Metals, vol. 299. Elsevier, 2023.","chicago":"Mahato, Neelima, Saurabh Singh, Mohammad Faisal, T. V.M. Sreekanth, Sutripto Majumder, Kisoo Yoo, and Jonghoon Kim. “Polycrystalline Phases Grown In-Situ Engendering Unique Mechanism of Charge Storage in Polyaniline-Graphite Composite.” Synthetic Metals. Elsevier, 2023. https://doi.org/10.1016/j.synthmet.2023.117463.","apa":"Mahato, N., Singh, S., Faisal, M., Sreekanth, T. V. M., Majumder, S., Yoo, K., & Kim, J. (2023). Polycrystalline phases grown in-situ engendering unique mechanism of charge storage in polyaniline-graphite composite. Synthetic Metals. Elsevier. https://doi.org/10.1016/j.synthmet.2023.117463","ista":"Mahato N, Singh S, Faisal M, Sreekanth TVM, Majumder S, Yoo K, Kim J. 2023. Polycrystalline phases grown in-situ engendering unique mechanism of charge storage in polyaniline-graphite composite. Synthetic Metals. 299, 117463."},"department":[{"_id":"MaIb"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2023-11-01T00:00:00Z","intvolume":" 299","day":"01","quality_controlled":"1"},{"has_accepted_license":"1","acknowledgement":"The authors would like to thank Mr. Joel Dietz for management of the mouse colony and helpful advice for conducting quantitative PCR studies and Mr. Santoshi Kinoshita at the Translational Research Initiative in Pathology laboratory at the University of Wisconsin-Madison for cutting sections analyzed in this study.\r\nThis work was supported by National Eye Institute grants R01 EY030123 (RWN), R01 EY018606 (RTL), P30 EY016665 (Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison), T32 EY027721 (RJD) and F31 EY030739 (OJM). Additional funding was provided by the BrightFocus Foundation (RWN) and unrestricted grants from Research to Prevent Blindness, Inc to the Department of Ophthalmology and Visual Sciences (University of Wisconsin-Madison) and to the Department of Ophthalmology (University of Rochester).","article_number":"67","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file_date_updated":"2024-01-30T14:33:31Z","type":"journal_article","pmid":1,"oa":1,"doi":"10.1186/s13024-023-00659-8","day":"26","quality_controlled":"1","date_published":"2023-09-26T00:00:00Z","intvolume":" 18","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"short":"M.E. Maes, R.J. Donahue, C.L. Schlamp, O.J. Marola, R.T. Libby, R.W. Nickells, Molecular Neurodegeneration 18 (2023).","ama":"Maes ME, Donahue RJ, Schlamp CL, Marola OJ, Libby RT, Nickells RW. BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps. Molecular Neurodegeneration. 2023;18. doi:10.1186/s13024-023-00659-8","ieee":"M. E. Maes, R. J. Donahue, C. L. Schlamp, O. J. Marola, R. T. Libby, and R. W. Nickells, “BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps,” Molecular Neurodegeneration, vol. 18. Springer Nature, 2023.","chicago":"Maes, Margaret E, Ryan J. Donahue, Cassandra L. Schlamp, Olivia J. Marola, Richard T. Libby, and Robert W. Nickells. “BAX Activation in Mouse Retinal Ganglion Cells Occurs in Two Temporally and Mechanistically Distinct Steps.” Molecular Neurodegeneration. Springer Nature, 2023. https://doi.org/10.1186/s13024-023-00659-8.","apa":"Maes, M. E., Donahue, R. J., Schlamp, C. L., Marola, O. J., Libby, R. T., & Nickells, R. W. (2023). BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps. Molecular Neurodegeneration. Springer Nature. https://doi.org/10.1186/s13024-023-00659-8","ista":"Maes ME, Donahue RJ, Schlamp CL, Marola OJ, Libby RT, Nickells RW. 2023. BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps. Molecular Neurodegeneration. 18, 67.","mla":"Maes, Margaret E., et al. “BAX Activation in Mouse Retinal Ganglion Cells Occurs in Two Temporally and Mechanistically Distinct Steps.” Molecular Neurodegeneration, vol. 18, 67, Springer Nature, 2023, doi:10.1186/s13024-023-00659-8."},"department":[{"_id":"SaSi"}],"publisher":"Springer Nature","publication_identifier":{"eissn":["1750-1326"]},"article_processing_charge":"Yes","date_created":"2023-10-08T22:01:15Z","external_id":{"isi":["001071403800001"],"pmid":["37752598"]},"oa_version":"Published Version","abstract":[{"text":"Background: \r\nPro-apoptotic BAX is a central mediator of retinal ganglion cell (RGC) death after optic nerve damage. BAX activation occurs in two stages including translocation of latent BAX to the mitochondrial outer membrane (MOM) and then permeabilization of the MOM to facilitate the release of apoptotic signaling molecules. As a critical component of RGC death, BAX is an attractive target for neuroprotective therapies and an understanding of the kinetics of BAX activation and the mechanisms controlling the two stages of this process in RGCs is potentially valuable in informing the development of a neuroprotective strategy.\r\nMethods:\r\nThe kinetics of BAX translocation were assessed by both static and live-cell imaging of a GFP-BAX fusion protein introduced into RGCs using AAV2-mediated gene transfer in mice. Activation of BAX was achieved using an acute optic nerve crush (ONC) protocol. Live-cell imaging of GFP-BAX was achieved using explants of mouse retina harvested 7 days after ONC. Kinetics of translocation in RGCs were compared to GFP-BAX translocation in 661W tissue culture cells. Permeabilization of GFP-BAX was assessed by staining with the 6A7 monoclonal antibody, which recognizes a conformational change in this protein after MOM insertion. Assessment of individual kinases associated with both stages of activation was made using small molecule inhibitors injected into the vitreous either independently or in concert with ONC surgery. The contribution of the Dual Leucine Zipper-JUN-N-Terminal Kinase cascade was evaluated using mice with a double conditional knock-out of both Mkk4 and Mkk7.\r\nResults:\r\nONC induces the translocation of GFP-BAX in RGCs at a slower rate and with less intracellular synchronicity than 661W cells, but exhibits less variability among mitochondrial foci within a single cell. GFP-BAX was also found to translocate in all compartments of an RGC including the dendritic arbor and axon. Approximately 6% of translocating RGCs exhibited retrotranslocation of BAX immediately following translocation. Unlike tissue culture cells, which exhibit simultaneous translocation and permeabilization, RGCs exhibited a significant delay between these two stages, similar to detached cells undergoing anoikis. Translocation, with minimal permeabilization could be induced in a subset of RGCs using an inhibitor of Focal Adhesion Kinase (PF573228). Permeabilization after ONC, in a majority of RGCs, could be inhibited with a broad spectrum kinase inhibitor (sunitinib) or a selective inhibitor for p38/MAPK14 (SB203580). Intervention of DLK-JNK axis signaling abrogated GFP-BAX translocation after ONC.\r\nConclusions:\r\nA comparison between BAX activation kinetics in tissue culture cells and in cells of a complex tissue environment shows distinct differences indicating that caution should be used when translating findings from one condition to the other. RGCs exhibit both a delay between translocation and permeabilization and the ability for translocated BAX to be retrotranslocated, suggesting several stages at which intervention of the activation process could be exploited in the design of a therapeutic strategy.","lang":"eng"}],"isi":1,"volume":18,"year":"2023","ddc":["570"],"date_updated":"2025-04-23T13:09:05Z","publication_status":"published","author":[{"full_name":"Maes, Margaret E","orcid":"0000-0001-9642-1085","first_name":"Margaret E","last_name":"Maes","id":"3838F452-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Donahue, Ryan J.","first_name":"Ryan J.","last_name":"Donahue"},{"first_name":"Cassandra L.","full_name":"Schlamp, Cassandra L.","last_name":"Schlamp"},{"last_name":"Marola","full_name":"Marola, Olivia J.","first_name":"Olivia J."},{"last_name":"Libby","first_name":"Richard T.","full_name":"Libby, Richard T."},{"first_name":"Robert W.","full_name":"Nickells, Robert W.","last_name":"Nickells"}],"month":"09","_id":"14401","language":[{"iso":"eng"}],"publication":"Molecular Neurodegeneration","article_type":"original","title":"BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps","scopus_import":"1","status":"public","file":[{"success":1,"date_created":"2024-01-30T14:33:31Z","date_updated":"2024-01-30T14:33:31Z","file_size":11568350,"checksum":"3aa218ddea4a082d8fd5e196ae55ca06","content_type":"application/pdf","access_level":"open_access","relation":"main_file","file_name":"2023_MolecularNeurodegeneration_Maes.pdf","creator":"dernst","file_id":"14917"}]},{"related_material":{"record":[{"id":"10821","relation":"earlier_version","status":"public"}]},"external_id":{"isi":["001086695500001"],"pmid":["37777965"]},"date_created":"2023-10-08T22:01:15Z","oa_version":"Published Version","ec_funded":1,"abstract":[{"lang":"eng","text":"Alpha oscillations are a distinctive feature of the awake resting state of the human brain. However, their functional role in resting-state neuronal dynamics remains poorly understood. Here we show that, during resting wakefulness, alpha oscillations drive an alternation of attenuation and amplification bouts in neural activity. Our analysis indicates that inhibition is activated in pulses that last for a single alpha cycle and gradually suppress neural activity, while excitation is successively enhanced over a few alpha cycles to amplify neural activity. Furthermore, we show that long-term alpha amplitude fluctuations—the “waxing and waning” phenomenon—are an attenuation-amplification mechanism described by a power-law decay of the activity rate in the “waning” phase. Importantly, we do not observe such dynamics during non-rapid eye movement (NREM) sleep with marginal alpha oscillations. The results suggest that alpha oscillations modulate neural activity not only through pulses of inhibition (pulsed inhibition hypothesis) but also by timely enhancement of excitation (or disinhibition)."}],"volume":42,"project":[{"grant_number":"M03318","_id":"eb943429-77a9-11ec-83b8-9f471cdf5c67","name":"Functional Advantages of Critical Brain Dynamics"},{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"}],"isi":1,"year":"2023","ddc":["570"],"date_updated":"2025-04-15T06:55:02Z","publication_status":"published","month":"10","author":[{"id":"A057D288-3E88-11E9-986D-0CF4E5697425","last_name":"Lombardi","first_name":"Fabrizio","orcid":"0000-0003-2623-5249","full_name":"Lombardi, Fabrizio"},{"last_name":"Herrmann","full_name":"Herrmann, Hans J.","first_name":"Hans J."},{"last_name":"Parrino","full_name":"Parrino, Liborio","first_name":"Liborio"},{"first_name":"Dietmar","full_name":"Plenz, Dietmar","last_name":"Plenz"},{"last_name":"Scarpetta","first_name":"Silvia","full_name":"Scarpetta, Silvia"},{"last_name":"Vaudano","first_name":"Anna Elisabetta","full_name":"Vaudano, Anna Elisabetta"},{"full_name":"De Arcangelis, Lucilla","first_name":"Lucilla","last_name":"De Arcangelis"},{"last_name":"Shriki","full_name":"Shriki, Oren","first_name":"Oren"}],"_id":"14402","publication":"Cell Reports","language":[{"iso":"eng"}],"article_type":"original","title":"Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting state","file":[{"file_id":"14914","creator":"dernst","relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_name":"2023_CellReports_Lombardi.pdf","checksum":"9c71eb2a03aa160415f01ad95f49ceb5","file_size":5599007,"date_created":"2024-01-30T14:07:08Z","success":1,"date_updated":"2024-01-30T14:07:08Z"}],"status":"public","scopus_import":"1","has_accepted_license":"1","acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) (grant PT1013M03318 to F.L.). For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission. The study was supported by the European Union Horizon 2020 Research and Innovation Program under the Marie Sklodowska-Curie action (grant agreement 754411 to F.L.) and in part by the NextGenerationEU through the grant TAlent in ReSearch@University of Padua – STARS@UNIPD (to F.L.) (project BRAINCIP [brain criticality and information processing]). L.d.A. acknowledges support from the Italian MIUR project PRIN2017WZFTZP and partial support from NEXTGENERATIONEU (NGEU) funded by the Ministry of University and Research (MUR), National Recovery and Resilience Plan (NRRP), and project MNESYS (PE0000006)—a multiscale integrated approach to the study of the nervous system in health and disease (DN. 1553 11.10.2022). O.S. acknowledges support from the Israel Science Foundation, grant 504/17. The work was supported in part by DIRP ZIAMH02797 (to D.P.).","article_number":"113162","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"corr_author":"1","file_date_updated":"2024-01-30T14:07:08Z","type":"journal_article","pmid":1,"oa":1,"doi":"10.1016/j.celrep.2023.113162","day":"31","quality_controlled":"1","date_published":"2023-10-31T00:00:00Z","intvolume":" 42","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ama":"Lombardi F, Herrmann HJ, Parrino L, et al. Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting state. Cell Reports. 2023;42(10). doi:10.1016/j.celrep.2023.113162","short":"F. Lombardi, H.J. Herrmann, L. Parrino, D. Plenz, S. Scarpetta, A.E. Vaudano, L. De Arcangelis, O. Shriki, Cell Reports 42 (2023).","mla":"Lombardi, Fabrizio, et al. “Beyond Pulsed Inhibition: Alpha Oscillations Modulate Attenuation and Amplification of Neural Activity in the Awake Resting State.” Cell Reports, vol. 42, no. 10, 113162, Elsevier, 2023, doi:10.1016/j.celrep.2023.113162.","ista":"Lombardi F, Herrmann HJ, Parrino L, Plenz D, Scarpetta S, Vaudano AE, De Arcangelis L, Shriki O. 2023. Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting state. Cell Reports. 42(10), 113162.","ieee":"F. Lombardi et al., “Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting state,” Cell Reports, vol. 42, no. 10. Elsevier, 2023.","chicago":"Lombardi, Fabrizio, Hans J. Herrmann, Liborio Parrino, Dietmar Plenz, Silvia Scarpetta, Anna Elisabetta Vaudano, Lucilla De Arcangelis, and Oren Shriki. “Beyond Pulsed Inhibition: Alpha Oscillations Modulate Attenuation and Amplification of Neural Activity in the Awake Resting State.” Cell Reports. Elsevier, 2023. https://doi.org/10.1016/j.celrep.2023.113162.","apa":"Lombardi, F., Herrmann, H. J., Parrino, L., Plenz, D., Scarpetta, S., Vaudano, A. E., … Shriki, O. (2023). Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting state. Cell Reports. Elsevier. https://doi.org/10.1016/j.celrep.2023.113162"},"department":[{"_id":"GaTk"}],"issue":"10","publisher":"Elsevier","publication_identifier":{"eissn":["2211-1247"]},"article_processing_charge":"Yes"},{"publication":"Science","language":[{"iso":"eng"}],"_id":"14404","status":"public","scopus_import":"1","title":"Widening the use of 3D printing","article_type":"letter_note","publication_status":"published","date_updated":"2025-09-09T13:04:47Z","month":"09","author":[{"first_name":"Daniel","orcid":"0000-0001-7597-043X","full_name":"Balazs, Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","last_name":"Balazs"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria"}],"page":"1413-1414","abstract":[{"text":"A light-triggered fabrication method extends the functionality of printable nanomaterials","lang":"eng"}],"year":"2023","volume":381,"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"isi":1,"external_id":{"isi":["001100656800023"],"pmid":["37769110"]},"date_created":"2023-10-08T22:01:16Z","oa_version":"None","issue":"6665","publisher":"AAAS","citation":{"ista":"Balazs D, Ibáñez M. 2023. Widening the use of 3D printing. Science. 381(6665), 1413–1414.","ieee":"D. Balazs and M. Ibáñez, “Widening the use of 3D printing,” Science, vol. 381, no. 6665. AAAS, pp. 1413–1414, 2023.","chicago":"Balazs, Daniel, and Maria Ibáñez. “Widening the Use of 3D Printing.” Science. AAAS, 2023. https://doi.org/10.1126/science.adk3070.","apa":"Balazs, D., & Ibáñez, M. (2023). Widening the use of 3D printing. Science. AAAS. https://doi.org/10.1126/science.adk3070","mla":"Balazs, Daniel, and Maria Ibáñez. “Widening the Use of 3D Printing.” Science, vol. 381, no. 6665, AAAS, 2023, pp. 1413–14, doi:10.1126/science.adk3070.","short":"D. Balazs, M. Ibáñez, Science 381 (2023) 1413–1414.","ama":"Balazs D, Ibáñez M. Widening the use of 3D printing. Science. 2023;381(6665):1413-1414. doi:10.1126/science.adk3070"},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"MaIb"},{"_id":"LifeSc"}],"article_processing_charge":"No","publication_identifier":{"eissn":["1095-9203"]},"quality_controlled":"1","day":"29","intvolume":" 381","date_published":"2023-09-29T00:00:00Z","type":"journal_article","pmid":1,"doi":"10.1126/science.adk3070","acknowledgement":"The authors thank the Werner-Siemens-Stiftung and the Institute of Science and Technology Austria for financial support.","corr_author":"1"},{"related_material":{"record":[{"status":"public","id":"20866","relation":"later_version"}]},"external_id":{"arxiv":["2305.02836"]},"date_created":"2023-10-08T22:01:16Z","oa_version":"Published Version","abstract":[{"lang":"eng","text":"We introduce hypernode automata as a new specification formalism for hyperproperties of concurrent systems. They are finite automata with nodes labeled with hypernode logic formulas and transitions labeled with actions. A hypernode logic formula specifies relations between sequences of variable values in different system executions. Unlike HyperLTL, hypernode logic takes an asynchronous view on execution traces by constraining the values and the order of value changes of each variable without correlating the timing of the changes. Different execution traces are synchronized solely through the transitions of hypernode automata. Hypernode automata naturally combine asynchronicity at the node level with synchronicity at the transition level. We show that the model-checking problem for hypernode automata is decidable over action-labeled Kripke structures, whose actions induce transitions of the specification automata. For this reason, hypernode automaton is a suitable formalism for specifying and verifying asynchronous hyperproperties, such as declassifying observational determinism in multi-threaded programs."}],"ec_funded":1,"volume":279,"project":[{"grant_number":"101020093","name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"}],"year":"2023","ddc":["000"],"date_updated":"2026-01-05T12:27:40Z","publication_status":"published","month":"09","author":[{"full_name":"Bartocci, Ezio","first_name":"Ezio","last_name":"Bartocci"},{"full_name":"Henzinger, Thomas A","first_name":"Thomas A","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger"},{"first_name":"Dejan","full_name":"Nickovic, Dejan","id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87","last_name":"Nickovic"},{"last_name":"Oliveira da Costa","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4","full_name":"Oliveira da Costa, Ana","orcid":"0000-0002-8741-5799","first_name":"Ana"}],"_id":"14405","publication":"34th International Conference on Concurrency Theory","language":[{"iso":"eng"}],"title":"Hypernode automata","scopus_import":"1","file":[{"file_name":"2023_LIPcs_Bartocci.pdf","content_type":"application/pdf","access_level":"open_access","relation":"main_file","creator":"dernst","file_id":"14413","date_updated":"2023-10-09T07:42:45Z","success":1,"date_created":"2023-10-09T07:42:45Z","checksum":"215765e40454d806174ac0a223e8d6fa","file_size":795790}],"status":"public","has_accepted_license":"1","acknowledgement":"This work was supported in part by the Austrian Science Fund (FWF) SFB project\r\nSpyCoDe F8502, by the FWF projects ZK-35 and W1255-N23, and by the ERC Advanced Grant\r\nVAMOS 101020093.","article_number":"21","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"corr_author":"1","conference":{"end_date":"2023-09-22","location":"Antwerp, Belgium","start_date":"2023-09-19","name":"CONCUR: Conference on Concurrency Theory"},"file_date_updated":"2023-10-09T07:42:45Z","type":"conference","oa":1,"doi":"10.4230/LIPIcs.CONCUR.2023.21","day":"01","arxiv":1,"quality_controlled":"1","date_published":"2023-09-01T00:00:00Z","intvolume":" 279","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","alternative_title":["LIPIcs"],"citation":{"ama":"Bartocci E, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata. In: 34th International Conference on Concurrency Theory. Vol 279. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2023. doi:10.4230/LIPIcs.CONCUR.2023.21","short":"E. Bartocci, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, in:, 34th International Conference on Concurrency Theory, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023.","mla":"Bartocci, Ezio, et al. “Hypernode Automata.” 34th International Conference on Concurrency Theory, vol. 279, 21, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023, doi:10.4230/LIPIcs.CONCUR.2023.21.","ista":"Bartocci E, Henzinger TA, Nickovic D, Oliveira da Costa A. 2023. Hypernode automata. 34th International Conference on Concurrency Theory. CONCUR: Conference on Concurrency Theory, LIPIcs, vol. 279, 21.","apa":"Bartocci, E., Henzinger, T. A., Nickovic, D., & Oliveira da Costa, A. (2023). Hypernode automata. In 34th International Conference on Concurrency Theory (Vol. 279). Antwerp, Belgium: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.CONCUR.2023.21","ieee":"E. Bartocci, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode automata,” in 34th International Conference on Concurrency Theory, Antwerp, Belgium, 2023, vol. 279.","chicago":"Bartocci, Ezio, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Hypernode Automata.” In 34th International Conference on Concurrency Theory, Vol. 279. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023. https://doi.org/10.4230/LIPIcs.CONCUR.2023.21."},"department":[{"_id":"ToHe"}],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","publication_identifier":{"issn":["1868-8969"],"isbn":["9783959772990"]},"article_processing_charge":"Yes"},{"intvolume":" 108","date_published":"2023-09-01T00:00:00Z","quality_controlled":"1","day":"01","arxiv":1,"article_processing_charge":"No","publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","citation":{"short":"S. Babkin, J.F. Karcher, I.S. Burmistrov, A.D. Mirlin, Physical Review B 108 (2023).","ama":"Babkin S, Karcher JF, Burmistrov IS, Mirlin AD. Generalized surface multifractality in two-dimensional disordered systems. Physical Review B. 2023;108(10). doi:10.1103/PhysRevB.108.104205","ista":"Babkin S, Karcher JF, Burmistrov IS, Mirlin AD. 2023. Generalized surface multifractality in two-dimensional disordered systems. Physical Review B. 108(10), 104205.","apa":"Babkin, S., Karcher, J. F., Burmistrov, I. S., & Mirlin, A. D. (2023). Generalized surface multifractality in two-dimensional disordered systems. Physical Review B. American Physical Society. https://doi.org/10.1103/PhysRevB.108.104205","ieee":"S. Babkin, J. F. Karcher, I. S. Burmistrov, and A. D. Mirlin, “Generalized surface multifractality in two-dimensional disordered systems,” Physical Review B, vol. 108, no. 10. American Physical Society, 2023.","chicago":"Babkin, Serafim, Jonas F. Karcher, Igor S. Burmistrov, and Alexander D. Mirlin. “Generalized Surface Multifractality in Two-Dimensional Disordered Systems.” Physical Review B. American Physical Society, 2023. https://doi.org/10.1103/PhysRevB.108.104205.","mla":"Babkin, Serafim, et al. “Generalized Surface Multifractality in Two-Dimensional Disordered Systems.” Physical Review B, vol. 108, no. 10, 104205, American Physical Society, 2023, doi:10.1103/PhysRevB.108.104205."},"department":[{"_id":"MaSe"}],"issue":"10","publisher":"American Physical Society","article_number":"104205","acknowledgement":"We thank Ilya Gruzberg for many illuminating discussions. S.S.B., J.F.K., and A.D.M. acknowledge support by the Deutsche Forschungsgemeinschaft (DFG) via the Grant\r\nNo. MI 658/14-1. I.S.B. acknowledges support from Russian Science Foundation (Grant No. 22-42-04416).","doi":"10.1103/PhysRevB.108.104205","oa":1,"type":"journal_article","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2306.09455","open_access":"1"}],"month":"09","author":[{"full_name":"Babkin, Serafim","first_name":"Serafim","orcid":"0009-0003-7382-8036","id":"41e64307-6672-11ee-b9ad-cc7a0075a479","last_name":"Babkin"},{"first_name":"Jonas F.","full_name":"Karcher, Jonas F.","last_name":"Karcher"},{"last_name":"Burmistrov","first_name":"Igor S.","full_name":"Burmistrov, Igor S."},{"full_name":"Mirlin, Alexander D.","first_name":"Alexander D.","last_name":"Mirlin"}],"date_updated":"2025-09-09T13:03:44Z","publication_status":"published","title":"Generalized surface multifractality in two-dimensional disordered systems","scopus_import":"1","status":"public","article_type":"original","language":[{"iso":"eng"}],"publication":"Physical Review B","_id":"14406","oa_version":"Preprint","external_id":{"arxiv":["2306.09455"],"isi":["001186160100001"]},"date_created":"2023-10-08T22:01:17Z","isi":1,"volume":108,"year":"2023","abstract":[{"lang":"eng","text":"Recently, a concept of generalized multifractality, which characterizes fluctuations and correlations of critical eigenstates, was introduced and explored for all 10 symmetry classes of disordered systems. Here, by using the nonlinear sigma-model (\r\nNL\r\nσ\r\nM\r\n) field theory, we extend the theory of generalized multifractality to boundaries of systems at criticality. Our numerical simulations on two-dimensional systems of symmetry classes A, C, and AII fully confirm the analytical predictions of pure-scaling observables and Weyl symmetry relations between critical exponents of surface generalized multifractality. This demonstrates the validity of the \r\nNL\r\nσ\r\nM\r\n for the description of Anderson-localization critical phenomena, not only in the bulk but also on the boundary. The critical exponents strongly violate generalized parabolicity, in analogy with earlier results for the bulk, corroborating the conclusion that the considered Anderson-localization critical points are not described by conformal field theories. We further derive relations between generalized surface multifractal spectra and linear combinations of Lyapunov exponents of a strip in quasi-one-dimensional geometry, which hold under the assumption of invariance with respect to a logarithmic conformal map. Our numerics demonstrate that these relations hold with an excellent accuracy. Taken together, our results indicate an intriguing situation: the conformal invariance is broken but holds partially at critical points of Anderson localization."}]},{"oa_version":"Published Version","external_id":{"isi":["001072666500001"]},"date_created":"2023-10-08T22:01:18Z","year":"2023","volume":26,"isi":1,"abstract":[{"text":"We present a photon- and metal-free approach for the radical fluorination of aliphatic oxalate-activated alcohols. The method relies on the spontaneous generation of the N-(chloromethyl)triethylenediamine radical dication, a potent single electron oxidant, from Selectfluor and 4-(dimethylamino)pyridine. The protocol is easily scalable and provides the desired fluorinated products within only a few minutes reaction time.","lang":"eng"}],"month":"11","author":[{"first_name":"Haralds","full_name":"Baunis, Haralds","last_name":"Baunis","id":"2eea55ec-e8ec-11ed-86cb-d9c76787acfe"},{"orcid":"0000-0001-8689-388X","first_name":"Bartholomäus","full_name":"Pieber, Bartholomäus","last_name":"Pieber","id":"93e5e5b2-0da6-11ed-8a41-af589a024726"}],"ddc":["540"],"publication_status":"published","date_updated":"2024-10-09T21:07:03Z","article_type":"original","file":[{"success":1,"date_created":"2024-01-30T14:04:44Z","date_updated":"2024-01-30T14:04:44Z","checksum":"e8ad7865acd94672e476f273ccf3d542","file_size":3277622,"relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_name":"2023_EurJOrgChem_Baunis.pdf","file_id":"14913","creator":"dernst"}],"status":"public","scopus_import":"1","title":"Formal radical deoxyfluorination of oxalate-activated alcohols triggered by the selectfluor-DMAP charge-transfer complex","_id":"14409","publication":"European Journal of Organic Chemistry","language":[{"iso":"eng"}],"corr_author":"1","acknowledgement":"We gratefully acknowledge the Max-Planck Society and the Institute of Science and Technology Austria (ISTA) for generous financial support. We also thank the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy – EXC 2008 – 390540038 – UniSysCat for funding. B.P. thanks the Boehringer Ingelheim Foundation for funding through the Plus 3 Perspectives Programme.","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"license":"https://creativecommons.org/licenses/by-nc/4.0/","article_number":"e202300769","oa":1,"doi":"10.1002/ejoc.202300769","type":"journal_article","file_date_updated":"2024-01-30T14:04:44Z","date_published":"2023-11-07T00:00:00Z","intvolume":" 26","day":"07","quality_controlled":"1","publication_identifier":{"issn":["1434-193X"],"eissn":["1099-0690"]},"article_processing_charge":"Yes (via OA deal)","issue":"42","publisher":"Wiley","department":[{"_id":"BaPi"}],"citation":{"ista":"Baunis H, Pieber B. 2023. Formal radical deoxyfluorination of oxalate-activated alcohols triggered by the selectfluor-DMAP charge-transfer complex. European Journal of Organic Chemistry. 26(42), e202300769.","chicago":"Baunis, Haralds, and Bartholomäus Pieber. “Formal Radical Deoxyfluorination of Oxalate-Activated Alcohols Triggered by the Selectfluor-DMAP Charge-Transfer Complex.” European Journal of Organic Chemistry. Wiley, 2023. https://doi.org/10.1002/ejoc.202300769.","ieee":"H. Baunis and B. Pieber, “Formal radical deoxyfluorination of oxalate-activated alcohols triggered by the selectfluor-DMAP charge-transfer complex,” European Journal of Organic Chemistry, vol. 26, no. 42. Wiley, 2023.","apa":"Baunis, H., & Pieber, B. (2023). Formal radical deoxyfluorination of oxalate-activated alcohols triggered by the selectfluor-DMAP charge-transfer complex. European Journal of Organic Chemistry. Wiley. https://doi.org/10.1002/ejoc.202300769","mla":"Baunis, Haralds, and Bartholomäus Pieber. “Formal Radical Deoxyfluorination of Oxalate-Activated Alcohols Triggered by the Selectfluor-DMAP Charge-Transfer Complex.” European Journal of Organic Chemistry, vol. 26, no. 42, e202300769, Wiley, 2023, doi:10.1002/ejoc.202300769.","short":"H. Baunis, B. Pieber, European Journal of Organic Chemistry 26 (2023).","ama":"Baunis H, Pieber B. Formal radical deoxyfluorination of oxalate-activated alcohols triggered by the selectfluor-DMAP charge-transfer complex. European Journal of Organic Chemistry. 2023;26(42). doi:10.1002/ejoc.202300769"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"abstract":[{"lang":"eng","text":"This paper focuses on the implementation details of the baseline methods and a recent lightweight conditional model extrapolation algorithm LIMES [5] for streaming data under class-prior shift. LIMES achieves superior performance over the baseline methods, especially concerning the minimum-across-day accuracy, which is important for the users of the system. In this work, the key measures to facilitate reproducibility and enhance the credibility of the results are described."}],"conference":{"name":"RRPR: Reproducible Research in Pattern Recognition","start_date":"2022-08-21","location":"Montreal, Canada","end_date":"2022-08-21"},"type":"conference","page":"67-73","volume":14068,"year":"2023","doi":"10.1007/978-3-031-40773-4_6","date_created":"2023-10-08T22:01:18Z","oa_version":"None","department":[{"_id":"ChLa"}],"_id":"14410","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","alternative_title":["LNCS"],"citation":{"ama":"Tomaszewska P, Lampert C. On the implementation of baselines and lightweight conditional model extrapolation (LIMES) under class-prior shift. In: International Workshop on Reproducible Research in Pattern Recognition. Vol 14068. Springer Nature; 2023:67-73. doi:10.1007/978-3-031-40773-4_6","short":"P. Tomaszewska, C. Lampert, in:, International Workshop on Reproducible Research in Pattern Recognition, Springer Nature, 2023, pp. 67–73.","mla":"Tomaszewska, Paulina, and Christoph Lampert. “On the Implementation of Baselines and Lightweight Conditional Model Extrapolation (LIMES) under Class-Prior Shift.” International Workshop on Reproducible Research in Pattern Recognition, vol. 14068, Springer Nature, 2023, pp. 67–73, doi:10.1007/978-3-031-40773-4_6.","ista":"Tomaszewska P, Lampert C. 2023. On the implementation of baselines and lightweight conditional model extrapolation (LIMES) under class-prior shift. International Workshop on Reproducible Research in Pattern Recognition. RRPR: Reproducible Research in Pattern Recognition, LNCS, vol. 14068, 67–73.","ieee":"P. Tomaszewska and C. Lampert, “On the implementation of baselines and lightweight conditional model extrapolation (LIMES) under class-prior shift,” in International Workshop on Reproducible Research in Pattern Recognition, Montreal, Canada, 2023, vol. 14068, pp. 67–73.","apa":"Tomaszewska, P., & Lampert, C. (2023). On the implementation of baselines and lightweight conditional model extrapolation (LIMES) under class-prior shift. In International Workshop on Reproducible Research in Pattern Recognition (Vol. 14068, pp. 67–73). Montreal, Canada: Springer Nature. https://doi.org/10.1007/978-3-031-40773-4_6","chicago":"Tomaszewska, Paulina, and Christoph Lampert. “On the Implementation of Baselines and Lightweight Conditional Model Extrapolation (LIMES) under Class-Prior Shift.” In International Workshop on Reproducible Research in Pattern Recognition, 14068:67–73. Springer Nature, 2023. https://doi.org/10.1007/978-3-031-40773-4_6."},"publisher":"Springer Nature","language":[{"iso":"eng"}],"publication":"International Workshop on Reproducible Research in Pattern Recognition","publication_identifier":{"issn":["0302-9743"],"isbn":["9783031407727"],"eissn":["1611-3349"]},"title":"On the implementation of baselines and lightweight conditional model extrapolation (LIMES) under class-prior shift","scopus_import":"1","article_processing_charge":"No","status":"public","day":"20","date_updated":"2023-10-09T06:48:02Z","quality_controlled":"1","publication_status":"published","date_published":"2023-08-20T00:00:00Z","intvolume":" 14068","author":[{"full_name":"Tomaszewska, Paulina","first_name":"Paulina","last_name":"Tomaszewska"},{"full_name":"Lampert, Christoph","first_name":"Christoph","orcid":"0000-0001-8622-7887","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","last_name":"Lampert"}],"month":"08"},{"file_date_updated":"2024-02-16T08:26:32Z","type":"conference","conference":{"location":"Luxembourg City, Luxembourg","end_date":"2023-09-15","name":"CMSB: Computational Methods in Systems Biology","start_date":"2023-09-13"},"doi":"10.1007/978-3-031-42697-1_2","oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"has_accepted_license":"1","acknowledgement":"This work was supported by the Czech Foundation grant No. GA22-10845S, Grant Agency of Masaryk University grant No. MUNI/G/1771/2020, and the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.","citation":{"ista":"Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. 2023. Phenotype control of partially specified boolean networks. 21st International Conference on Computational Methods in Systems Biology. CMSB: Computational Methods in Systems Biology, LNBI, vol. 14137, 18–35.","ieee":"N. Beneš, L. Brim, S. Pastva, D. Šafránek, and E. Šmijáková, “Phenotype control of partially specified boolean networks,” in 21st International Conference on Computational Methods in Systems Biology, Luxembourg City, Luxembourg, 2023, vol. 14137, pp. 18–35.","chicago":"Beneš, Nikola, Luboš Brim, Samuel Pastva, David Šafránek, and Eva Šmijáková. “Phenotype Control of Partially Specified Boolean Networks.” In 21st International Conference on Computational Methods in Systems Biology, 14137:18–35. Springer Nature, 2023. https://doi.org/10.1007/978-3-031-42697-1_2.","apa":"Beneš, N., Brim, L., Pastva, S., Šafránek, D., & Šmijáková, E. (2023). Phenotype control of partially specified boolean networks. In 21st International Conference on Computational Methods in Systems Biology (Vol. 14137, pp. 18–35). Luxembourg City, Luxembourg: Springer Nature. https://doi.org/10.1007/978-3-031-42697-1_2","mla":"Beneš, Nikola, et al. “Phenotype Control of Partially Specified Boolean Networks.” 21st International Conference on Computational Methods in Systems Biology, vol. 14137, Springer Nature, 2023, pp. 18–35, doi:10.1007/978-3-031-42697-1_2.","short":"N. Beneš, L. Brim, S. Pastva, D. Šafránek, E. Šmijáková, in:, 21st International Conference on Computational Methods in Systems Biology, Springer Nature, 2023, pp. 18–35.","ama":"Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. Phenotype control of partially specified boolean networks. In: 21st International Conference on Computational Methods in Systems Biology. Vol 14137. Springer Nature; 2023:18-35. doi:10.1007/978-3-031-42697-1_2"},"alternative_title":["LNBI"],"department":[{"_id":"ToHe"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publisher":"Springer Nature","article_processing_charge":"No","publication_identifier":{"issn":["0302-9743"],"isbn":["9783031426964"],"eissn":["1611-3349"]},"quality_controlled":"1","day":"09","intvolume":" 14137","date_published":"2023-09-09T00:00:00Z","page":"18-35","ec_funded":1,"abstract":[{"lang":"eng","text":"Partially specified Boolean networks (PSBNs) represent a promising framework for the qualitative modelling of biological systems in which the logic of interactions is not completely known. Phenotype control aims to stabilise the network in states exhibiting specific traits.\r\nIn this paper, we define the phenotype control problem in the context of asynchronous PSBNs and propose a novel semi-symbolic algorithm for solving this problem with permanent variable perturbations."}],"project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"isi":1,"volume":14137,"year":"2023","external_id":{"isi":["001156280600002"]},"date_created":"2023-10-08T22:01:18Z","oa_version":"Submitted Version","publication":"21st International Conference on Computational Methods in Systems Biology","language":[{"iso":"eng"}],"_id":"14411","title":"Phenotype control of partially specified boolean networks","scopus_import":"1","status":"public","file":[{"file_name":"cmsb2023.pdf","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_id":"14997","creator":"spastva","date_updated":"2024-02-16T08:26:32Z","date_created":"2024-02-16T08:26:32Z","success":1,"checksum":"6f71bdaedb770b52380222fd9f4d7937","file_size":691582}],"date_updated":"2025-09-09T14:25:46Z","publication_status":"published","ddc":["000"],"month":"09","author":[{"last_name":"Beneš","first_name":"Nikola","full_name":"Beneš, Nikola"},{"full_name":"Brim, Luboš","first_name":"Luboš","last_name":"Brim"},{"id":"07c5ea74-f61c-11ec-a664-aa7c5d957b2b","last_name":"Pastva","first_name":"Samuel","orcid":"0000-0003-1993-0331","full_name":"Pastva, Samuel"},{"last_name":"Šafránek","first_name":"David","full_name":"Šafránek, David"},{"full_name":"Šmijáková, Eva","first_name":"Eva","last_name":"Šmijáková"}]},{"article_number":"15","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"has_accepted_license":"1","acknowledgement":"This work was partly funded by the ERC CoG 863818 (ForM-SMArt), the DFG Grant\r\n389792660 as part of TRR 248 (Foundations of Perspicuous Software Systems), the Cluster of\r\nExcellence EXC 2050/1 (CeTI, project ID 390696704, as part of Germany’s Excellence Strategy), and the DFG projects BA-1679/11-1 and BA-1679/12-1.","corr_author":"1","file_date_updated":"2023-10-09T09:19:11Z","type":"conference","conference":{"name":"MFCS: Mathematical Foundations of Computer Science","start_date":"2023-08-28","location":"Bordeaux, France","end_date":"2023-09-01"},"doi":"10.4230/LIPIcs.MFCS.2023.15","oa":1,"quality_controlled":"1","arxiv":1,"day":"21","intvolume":" 272","date_published":"2023-08-21T00:00:00Z","department":[{"_id":"KrCh"}],"alternative_title":["LIPIcs"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Baier C, Chatterjee K, Meggendorfer T, Piribauer J. 2023. Entropic risk for turn-based stochastic games. 48th International Symposium on Mathematical Foundations of Computer Science. MFCS: Mathematical Foundations of Computer Science, LIPIcs, vol. 272, 15.","ieee":"C. Baier, K. Chatterjee, T. Meggendorfer, and J. Piribauer, “Entropic risk for turn-based stochastic games,” in 48th International Symposium on Mathematical Foundations of Computer Science, Bordeaux, France, 2023, vol. 272.","apa":"Baier, C., Chatterjee, K., Meggendorfer, T., & Piribauer, J. (2023). Entropic risk for turn-based stochastic games. In 48th International Symposium on Mathematical Foundations of Computer Science (Vol. 272). Bordeaux, France: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.MFCS.2023.15","chicago":"Baier, Christel, Krishnendu Chatterjee, Tobias Meggendorfer, and Jakob Piribauer. “Entropic Risk for Turn-Based Stochastic Games.” In 48th International Symposium on Mathematical Foundations of Computer Science, Vol. 272. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023. https://doi.org/10.4230/LIPIcs.MFCS.2023.15.","mla":"Baier, Christel, et al. “Entropic Risk for Turn-Based Stochastic Games.” 48th International Symposium on Mathematical Foundations of Computer Science, vol. 272, 15, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023, doi:10.4230/LIPIcs.MFCS.2023.15.","short":"C. Baier, K. Chatterjee, T. Meggendorfer, J. Piribauer, in:, 48th International Symposium on Mathematical Foundations of Computer Science, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023.","ama":"Baier C, Chatterjee K, Meggendorfer T, Piribauer J. Entropic risk for turn-based stochastic games. In: 48th International Symposium on Mathematical Foundations of Computer Science. Vol 272. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2023. doi:10.4230/LIPIcs.MFCS.2023.15"},"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","article_processing_charge":"Yes","publication_identifier":{"isbn":["9783959772921"],"eissn":["1868-8969"]},"related_material":{"record":[{"relation":"later_version","id":"17474","status":"public"}]},"date_created":"2023-10-09T09:21:05Z","external_id":{"arxiv":["2307.06611"]},"oa_version":"Published Version","ec_funded":1,"abstract":[{"lang":"eng","text":"Entropic risk (ERisk) is an established risk measure in finance, quantifying risk by an exponential re-weighting of rewards. We study ERisk for the first time in the context of turn-based stochastic games with the total reward objective. This gives rise to an objective function that demands the control of systems in a risk-averse manner. We show that the resulting games are determined and, in particular, admit optimal memoryless deterministic strategies. This contrasts risk measures that previously have been considered in the special case of Markov decision processes and that require randomization and/or memory. We provide several results on the decidability and the computational complexity of the threshold problem, i.e. whether the optimal value of ERisk exceeds a given threshold. In the most general case, the problem is decidable subject to Shanuel’s conjecture. If all inputs are rational, the resulting threshold problem can be solved using algebraic numbers, leading to decidability via a polynomial-time reduction to the existential theory of the reals. Further restrictions on the encoding of the input allow the solution of the threshold problem in NP∩coNP. Finally, an approximation algorithm for the optimal value of ERisk is provided."}],"volume":272,"project":[{"_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","name":"Formal Methods for Stochastic Models: Algorithms and Applications","call_identifier":"H2020","grant_number":"863818"}],"year":"2023","date_updated":"2025-09-08T09:10:05Z","publication_status":"published","ddc":["000"],"month":"08","author":[{"last_name":"Baier","first_name":"Christel","full_name":"Baier, Christel"},{"last_name":"Chatterjee","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","full_name":"Chatterjee, Krishnendu","orcid":"0000-0002-4561-241X","first_name":"Krishnendu"},{"id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1","last_name":"Meggendorfer","first_name":"Tobias","orcid":"0000-0002-1712-2165","full_name":"Meggendorfer, Tobias"},{"last_name":"Piribauer","first_name":"Jakob","full_name":"Piribauer, Jakob"}],"language":[{"iso":"eng"}],"publication":"48th International Symposium on Mathematical Foundations of Computer Science","_id":"14417","title":"Entropic risk for turn-based stochastic games","file":[{"checksum":"402281b17ed669bbf149d0fdf68ac201","file_size":826843,"date_updated":"2023-10-09T09:19:11Z","date_created":"2023-10-09T09:19:11Z","success":1,"file_id":"14418","creator":"dernst","file_name":"2023_LIPIcsMFCS_Baier.pdf","relation":"main_file","access_level":"open_access","content_type":"application/pdf"}],"scopus_import":"1","status":"public"},{"year":"2023","volume":14,"isi":1,"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413"}],"ec_funded":1,"abstract":[{"lang":"eng","text":"Water adsorption and dissociation processes on pristine low-index TiO2 interfaces are important but poorly understood outside the well-studied anatase (101) and rutile (110). To understand these, we construct three sets of machine learning potentials that are simultaneously applicable to various TiO2 surfaces, based on three density-functional-theory approximations. Here we show the water dissociation free energies on seven pristine TiO2 surfaces, and predict that anatase (100), anatase (110), rutile (001), and rutile (011) favor water dissociation, anatase (101) and rutile (100) have mostly molecular adsorption, while the simulations of rutile (110) sensitively depend on the slab thickness and molecular adsorption is preferred with thick slabs. Moreover, using an automated algorithm, we reveal that these surfaces follow different types of atomistic mechanisms for proton transfer and water dissociation: one-step, two-step, or both. These mechanisms can be rationalized based on the arrangements of water molecules on the different surfaces. Our finding thus demonstrates that the different pristine TiO2 surfaces react with water in distinct ways, and cannot be represented using just the low-energy anatase (101) and rutile (110) surfaces."}],"oa_version":"Published Version","related_material":{"link":[{"relation":"software","url":"https://github.com/BingqingCheng/TiO2-water"}]},"external_id":{"isi":["001084354900008"],"arxiv":["2303.07433"],"pmid":["37783698"]},"date_created":"2023-10-15T22:01:10Z","scopus_import":"1","status":"public","file":[{"date_updated":"2023-10-16T07:34:49Z","date_created":"2023-10-16T07:34:49Z","success":1,"checksum":"7d1dffd36b672ec679f08f70ce79da87","file_size":3194116,"file_name":"2023_NatureComm_Zeng.pdf","access_level":"open_access","content_type":"application/pdf","relation":"main_file","creator":"dernst","file_id":"14432"}],"title":"Mechanistic insight on water dissociation on pristine low-index TiO2 surfaces from machine learning molecular dynamics simulations","article_type":"original","publication":"Nature Communications","language":[{"iso":"eng"}],"_id":"14425","month":"10","author":[{"first_name":"Zezhu","full_name":"Zeng, Zezhu","id":"54a2c730-803f-11ed-ab7e-95b29d2680e7","last_name":"Zeng"},{"full_name":"Wodaczek, Felix","orcid":"0009-0000-1457-795X","first_name":"Felix","last_name":"Wodaczek","id":"8b4b6a9f-32b0-11ee-9fa8-bbe85e26258e"},{"first_name":"Keyang","full_name":"Liu, Keyang","last_name":"Liu"},{"last_name":"Stein","full_name":"Stein, Frederick","first_name":"Frederick"},{"last_name":"Hutter","full_name":"Hutter, Jürg","first_name":"Jürg"},{"first_name":"Ji","full_name":"Chen, Ji","last_name":"Chen"},{"id":"cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9","last_name":"Cheng","full_name":"Cheng, Bingqing","first_name":"Bingqing","orcid":"0000-0002-3584-9632"}],"publication_status":"published","date_updated":"2025-04-14T07:54:53Z","ddc":["540","000"],"doi":"10.1038/s41467-023-41865-8","oa":1,"pmid":1,"type":"journal_article","file_date_updated":"2023-10-16T07:34:49Z","corr_author":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_number":"6131","acknowledgement":"F.S., J.H., and B.C. thank the Swiss National Supercomputing Centre (CSCS) for the generous allocation of CPU hours via production project s1108 at the Piz Daint supercomputer. B.C. acknowledges resources provided by the Cambridge Tier-2 system operated by the University of Cambridge Research Computing Service funded by EPSRC Tier-2 capital grant EP/P020259/1. J.C. acknowledges the Beijing Natural Science Foundation for support under grant No. JQ22001. F.S., and J.H. thank the Swiss Platform for Advanced Scientific Computing (PASC) via the 2021-2024 “Ab Initio Molecular Dynamics at the Exa-Scale” project. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413.","has_accepted_license":"1","article_processing_charge":"Yes","publication_identifier":{"eissn":["2041-1723"]},"publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"short":"Z. Zeng, F. Wodaczek, K. Liu, F. Stein, J. Hutter, J. Chen, B. Cheng, Nature Communications 14 (2023).","ama":"Zeng Z, Wodaczek F, Liu K, et al. Mechanistic insight on water dissociation on pristine low-index TiO2 surfaces from machine learning molecular dynamics simulations. Nature Communications. 2023;14. doi:10.1038/s41467-023-41865-8","chicago":"Zeng, Zezhu, Felix Wodaczek, Keyang Liu, Frederick Stein, Jürg Hutter, Ji Chen, and Bingqing Cheng. “Mechanistic Insight on Water Dissociation on Pristine Low-Index TiO2 Surfaces from Machine Learning Molecular Dynamics Simulations.” Nature Communications. Springer Nature, 2023. https://doi.org/10.1038/s41467-023-41865-8.","ieee":"Z. Zeng et al., “Mechanistic insight on water dissociation on pristine low-index TiO2 surfaces from machine learning molecular dynamics simulations,” Nature Communications, vol. 14. Springer Nature, 2023.","apa":"Zeng, Z., Wodaczek, F., Liu, K., Stein, F., Hutter, J., Chen, J., & Cheng, B. (2023). Mechanistic insight on water dissociation on pristine low-index TiO2 surfaces from machine learning molecular dynamics simulations. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-023-41865-8","ista":"Zeng Z, Wodaczek F, Liu K, Stein F, Hutter J, Chen J, Cheng B. 2023. Mechanistic insight on water dissociation on pristine low-index TiO2 surfaces from machine learning molecular dynamics simulations. Nature Communications. 14, 6131.","mla":"Zeng, Zezhu, et al. “Mechanistic Insight on Water Dissociation on Pristine Low-Index TiO2 Surfaces from Machine Learning Molecular Dynamics Simulations.” Nature Communications, vol. 14, 6131, Springer Nature, 2023, doi:10.1038/s41467-023-41865-8."},"department":[{"_id":"BiCh"},{"_id":"GradSch"}],"intvolume":" 14","date_published":"2023-10-02T00:00:00Z","quality_controlled":"1","arxiv":1,"day":"02"},{"abstract":[{"lang":"eng","text":"To meet the physiological demands of the body, organs need to establish a functional tissue architecture and adequate size as the embryo develops to adulthood. In the liver, uni- and bipotent progenitor differentiation into hepatocytes and biliary epithelial cells (BECs), and their relative proportions, comprise the functional architecture. Yet, the contribution of individual liver progenitors at the organ level to both fates, and their specific proportion, is unresolved. Combining mathematical modelling with organ-wide, multispectral FRaeppli-NLS lineage tracing in zebrafish, we demonstrate that a precise BEC-to-hepatocyte ratio is established (i) fast, (ii) solely by heterogeneous lineage decisions from uni- and bipotent progenitors, and (iii) independent of subsequent cell type–specific proliferation. Extending lineage tracing to adulthood determined that embryonic cells undergo spatially heterogeneous three-dimensional growth associated with distinct environments. Strikingly, giant clusters comprising almost half a ventral lobe suggest lobe-specific dominant-like growth behaviours. We show substantial hepatocyte polyploidy in juveniles representing another hallmark of postembryonic liver growth. Our findings uncover heterogeneous progenitor contributions to tissue architecture-defining cell type proportions and postembryonic organ growth as key mechanisms forming the adult liver."}],"ec_funded":1,"volume":21,"project":[{"grant_number":"851288","call_identifier":"H2020","name":"Design Principles of Branching Morphogenesis","_id":"05943252-7A3F-11EA-A408-12923DDC885E"}],"year":"2023","related_material":{"link":[{"relation":"software","url":"https://github.com/JulieKlepstad/LiverDevelopment"}]},"date_created":"2023-10-15T22:01:10Z","oa_version":"Published Version","language":[{"iso":"eng"}],"publication":"PLoS Biology","_id":"14426","title":"Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics","scopus_import":"1","status":"public","file":[{"file_id":"14431","creator":"dernst","file_name":"2023_PloSBiology_Unterweger.pdf","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_size":6193110,"checksum":"40a2b11b41d70a0e5939f8a52b66e389","date_updated":"2023-10-16T07:20:49Z","success":1,"date_created":"2023-10-16T07:20:49Z"}],"article_type":"original","date_updated":"2025-04-14T07:52:27Z","publication_status":"published","ddc":["570"],"author":[{"last_name":"Unterweger","first_name":"Iris A.","full_name":"Unterweger, Iris A."},{"last_name":"Klepstad","first_name":"Julie","full_name":"Klepstad, Julie"},{"full_name":"Hannezo, Edouard B","first_name":"Edouard B","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo"},{"full_name":"Lundegaard, Pia R.","first_name":"Pia R.","last_name":"Lundegaard"},{"last_name":"Trusina","first_name":"Ala","full_name":"Trusina, Ala"},{"first_name":"Elke A.","full_name":"Ober, Elke A.","last_name":"Ober"}],"month":"10","file_date_updated":"2023-10-16T07:20:49Z","type":"journal_article","doi":"10.1371/journal.pbio.3002315","oa":1,"article_number":"e3002315","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"has_accepted_license":"1","acknowledgement":"We thank the Ober group for discussion and comments on the manuscript. We are grateful to\r\nDr. F. Lemaigre for feedback on the manuscript and Dr. T. Piotrowski for invaluable support.\r\nWe thank the department of experimental medicine (AEM) in Copenhagen for expert fish\r\ncare. We gratefully acknowledge the DanStem Imaging Platform (University of Copenhagen)\r\nfor support and assistance in this work.\r\nThis work is supported by Novo Nordisk Foundation grant NNF17CC0027852 (EAO);\r\nNordisk Foundation grant NNF19OC0058327 (EAO); Novo Nordisk Foundation grant\r\nNNF17OC0031204 (PRL); https://novonordiskfonden.dk/en/; Danish National\r\nResearch Foundation grant DNRF116 (EAO and AT); https://dg.dk/en/; John and Birthe Meyer\r\nFoundation (PRL) and European Research Council (ERC) under the EU Horizon 2020 research and Innovation Programme Grant Agreement No. 851288 (EH).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"EdHa"}],"citation":{"ama":"Unterweger IA, Klepstad J, Hannezo EB, Lundegaard PR, Trusina A, Ober EA. Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics. PLoS Biology. 2023;21(10). doi:10.1371/journal.pbio.3002315","short":"I.A. Unterweger, J. Klepstad, E.B. Hannezo, P.R. Lundegaard, A. Trusina, E.A. Ober, PLoS Biology 21 (2023).","mla":"Unterweger, Iris A., et al. “Lineage Tracing Identifies Heterogeneous Hepatoblast Contribution to Cell Lineages and Postembryonic Organ Growth Dynamics.” PLoS Biology, vol. 21, no. 10, e3002315, Public Library of Science, 2023, doi:10.1371/journal.pbio.3002315.","ista":"Unterweger IA, Klepstad J, Hannezo EB, Lundegaard PR, Trusina A, Ober EA. 2023. Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics. PLoS Biology. 21(10), e3002315.","apa":"Unterweger, I. A., Klepstad, J., Hannezo, E. B., Lundegaard, P. R., Trusina, A., & Ober, E. A. (2023). Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics. PLoS Biology. Public Library of Science. https://doi.org/10.1371/journal.pbio.3002315","chicago":"Unterweger, Iris A., Julie Klepstad, Edouard B Hannezo, Pia R. Lundegaard, Ala Trusina, and Elke A. Ober. “Lineage Tracing Identifies Heterogeneous Hepatoblast Contribution to Cell Lineages and Postembryonic Organ Growth Dynamics.” PLoS Biology. Public Library of Science, 2023. https://doi.org/10.1371/journal.pbio.3002315.","ieee":"I. A. Unterweger, J. Klepstad, E. B. Hannezo, P. R. Lundegaard, A. Trusina, and E. A. Ober, “Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics,” PLoS Biology, vol. 21, no. 10. Public Library of Science, 2023."},"issue":"10","publisher":"Public Library of Science","article_processing_charge":"No","publication_identifier":{"eissn":["1545-7885"]},"quality_controlled":"1","day":"04","intvolume":" 21","date_published":"2023-10-04T00:00:00Z"},{"publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Chen J, Kaloshin V, Zhang HK. 2023. Length spectrum rigidity for piecewise analytic Bunimovich billiards. Communications in Mathematical Physics. 404, 1–50.","ieee":"J. Chen, V. Kaloshin, and H. K. Zhang, “Length spectrum rigidity for piecewise analytic Bunimovich billiards,” Communications in Mathematical Physics, vol. 404. Springer Nature, pp. 1–50, 2023.","chicago":"Chen, Jianyu, Vadim Kaloshin, and Hong Kun Zhang. “Length Spectrum Rigidity for Piecewise Analytic Bunimovich Billiards.” Communications in Mathematical Physics. Springer Nature, 2023. https://doi.org/10.1007/s00220-023-04837-z.","apa":"Chen, J., Kaloshin, V., & Zhang, H. K. (2023). Length spectrum rigidity for piecewise analytic Bunimovich billiards. Communications in Mathematical Physics. Springer Nature. https://doi.org/10.1007/s00220-023-04837-z","mla":"Chen, Jianyu, et al. “Length Spectrum Rigidity for Piecewise Analytic Bunimovich Billiards.” Communications in Mathematical Physics, vol. 404, Springer Nature, 2023, pp. 1–50, doi:10.1007/s00220-023-04837-z.","short":"J. Chen, V. Kaloshin, H.K. Zhang, Communications in Mathematical Physics 404 (2023) 1–50.","ama":"Chen J, Kaloshin V, Zhang HK. Length spectrum rigidity for piecewise analytic Bunimovich billiards. Communications in Mathematical Physics. 2023;404:1-50. doi:10.1007/s00220-023-04837-z"},"department":[{"_id":"VaKa"}],"publication_identifier":{"eissn":["1432-0916"],"issn":["0010-3616"]},"article_processing_charge":"No","arxiv":1,"day":"01","quality_controlled":"1","date_published":"2023-11-01T00:00:00Z","intvolume":" 404","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1902.07330"}],"type":"journal_article","oa":1,"doi":"10.1007/s00220-023-04837-z","acknowledgement":"VK acknowledges a partial support by the NSF grant DMS-1402164 and ERC Grant #885707. Discussions with Martin Leguil and Jacopo De Simoi were very useful. JC visited the University of Maryland and thanks for the hospitality. Also, JC was partially supported by the National Key Research and Development Program of China (No.2022YFA1005802), the NSFC Grant 12001392 and NSF of Jiangsu BK20200850. H.-K. Zhang is partially supported by the National Science Foundation (DMS-2220211), as well as Simons Foundation Collaboration Grants for Mathematicians (706383).","corr_author":"1","_id":"14427","publication":"Communications in Mathematical Physics","language":[{"iso":"eng"}],"article_type":"original","scopus_import":"1","status":"public","title":"Length spectrum rigidity for piecewise analytic Bunimovich billiards","publication_status":"published","date_updated":"2025-04-14T07:53:45Z","month":"11","author":[{"first_name":"Jianyu","full_name":"Chen, Jianyu","last_name":"Chen"},{"full_name":"Kaloshin, Vadim","first_name":"Vadim","orcid":"0000-0002-6051-2628","id":"FE553552-CDE8-11E9-B324-C0EBE5697425","last_name":"Kaloshin"},{"last_name":"Zhang","full_name":"Zhang, Hong Kun","first_name":"Hong Kun"}],"abstract":[{"lang":"eng","text":"In the paper, we establish Squash Rigidity Theorem—the dynamical spectral rigidity for piecewise analytic Bunimovich squash-type stadia whose convex arcs are homothetic. We also establish Stadium Rigidity Theorem—the dynamical spectral rigidity for piecewise analytic Bunimovich stadia whose flat boundaries are a priori fixed. In addition, for smooth Bunimovich squash-type stadia we compute the Lyapunov exponents along the maximal period two orbit, as well as the value of the Peierls’ Barrier function from the maximal marked length spectrum associated to the rotation number 2n/4n+1."}],"ec_funded":1,"page":"1-50","year":"2023","volume":404,"project":[{"name":"Spectral rigidity and integrability for billiards and geodesic flows","call_identifier":"H2020","_id":"9B8B92DE-BA93-11EA-9121-9846C619BF3A","grant_number":"885707"}],"isi":1,"date_created":"2023-10-15T22:01:11Z","external_id":{"isi":["001073177200001"],"arxiv":["1902.07330"]},"oa_version":"Preprint"},{"corr_author":"1","oa":1,"doi":"10.1007/978-3-031-38545-2_17","conference":{"name":"CRYPTO: Advances in Cryptology","start_date":"2023-08-20","location":"Santa Barbara, CA, United States","end_date":"2023-08-24"},"main_file_link":[{"url":"https://eprint.iacr.org/2023/1041","open_access":"1"}],"type":"conference","date_published":"2023-08-09T00:00:00Z","intvolume":" 14082","day":"09","quality_controlled":"1","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783031385445"],"issn":["0302-9743"]},"article_processing_charge":"No","publisher":"Springer Nature","department":[{"_id":"KrPi"}],"citation":{"ieee":"Y. Dodis, N. Ferguson, E. Goldin, P. Hall, and K. Z. Pietrzak, “Random oracle combiners: Breaking the concatenation barrier for collision-resistance,” in 43rd Annual International Cryptology Conference, Santa Barbara, CA, United States, 2023, vol. 14082, pp. 514–546.","apa":"Dodis, Y., Ferguson, N., Goldin, E., Hall, P., & Pietrzak, K. Z. (2023). Random oracle combiners: Breaking the concatenation barrier for collision-resistance. In 43rd Annual International Cryptology Conference (Vol. 14082, pp. 514–546). Santa Barbara, CA, United States: Springer Nature. https://doi.org/10.1007/978-3-031-38545-2_17","chicago":"Dodis, Yevgeniy, Niels Ferguson, Eli Goldin, Peter Hall, and Krzysztof Z Pietrzak. “Random Oracle Combiners: Breaking the Concatenation Barrier for Collision-Resistance.” In 43rd Annual International Cryptology Conference, 14082:514–46. Springer Nature, 2023. https://doi.org/10.1007/978-3-031-38545-2_17.","ista":"Dodis Y, Ferguson N, Goldin E, Hall P, Pietrzak KZ. 2023. Random oracle combiners: Breaking the concatenation barrier for collision-resistance. 43rd Annual International Cryptology Conference. CRYPTO: Advances in Cryptology, LNCS, vol. 14082, 514–546.","mla":"Dodis, Yevgeniy, et al. “Random Oracle Combiners: Breaking the Concatenation Barrier for Collision-Resistance.” 43rd Annual International Cryptology Conference, vol. 14082, Springer Nature, 2023, pp. 514–46, doi:10.1007/978-3-031-38545-2_17.","short":"Y. Dodis, N. Ferguson, E. Goldin, P. Hall, K.Z. Pietrzak, in:, 43rd Annual International Cryptology Conference, Springer Nature, 2023, pp. 514–546.","ama":"Dodis Y, Ferguson N, Goldin E, Hall P, Pietrzak KZ. Random oracle combiners: Breaking the concatenation barrier for collision-resistance. In: 43rd Annual International Cryptology Conference. Vol 14082. Springer Nature; 2023:514-546. doi:10.1007/978-3-031-38545-2_17"},"alternative_title":["LNCS"],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa_version":"Preprint","date_created":"2023-10-15T22:01:11Z","external_id":{"isi":["001314616100017"]},"year":"2023","isi":1,"volume":14082,"abstract":[{"text":"Suppose we have two hash functions h1 and h2, but we trust the security of only one of them. To mitigate this worry, we wish to build a hash combiner Ch1,h2 which is secure so long as one of the underlying hash functions is. This question has been well-studied in the regime of collision resistance. In this case, concatenating the two hash function outputs clearly works. Unfortunately, a long series of works (Boneh and Boyen, CRYPTO’06; Pietrzak, Eurocrypt’07; Pietrzak, CRYPTO’08) showed no (noticeably) shorter combiner for collision resistance is possible.\r\nIn this work, we revisit this pessimistic state of affairs, motivated by the observation that collision-resistance is insufficient for many interesting applications of cryptographic hash functions anyway. We argue the right formulation of the “hash combiner” is to build what we call random oracle (RO) combiners, utilizing stronger assumptions for stronger constructions.\r\nIndeed, we circumvent the previous lower bounds for collision resistance by constructing a simple length-preserving RO combiner C˜h1,h2Z1,Z2(M)=h1(M,Z1)⊕h2(M,Z2),where Z1,Z2\r\n are random salts of appropriate length. We show that this extra randomness is necessary for RO combiners, and indeed our construction is somewhat tight with this lower bound.\r\nOn the negative side, we show that one cannot generically apply the composition theorem to further replace “monolithic” hash functions h1 and h2 by some simpler indifferentiable construction (such as the Merkle-Damgård transformation) from smaller components, such as fixed-length compression functions. Finally, despite this issue, we directly prove collision resistance of the Merkle-Damgård variant of our combiner, where h1 and h2 are replaced by iterative Merkle-Damgård hashes applied to a fixed-length compression function. Thus, we can still subvert the concatenation barrier for collision-resistance combiners while utilizing practically small fixed-length components underneath.","lang":"eng"}],"page":"514-546","month":"08","author":[{"first_name":"Yevgeniy","full_name":"Dodis, Yevgeniy","last_name":"Dodis"},{"first_name":"Niels","full_name":"Ferguson, Niels","last_name":"Ferguson"},{"last_name":"Goldin","first_name":"Eli","full_name":"Goldin, Eli"},{"last_name":"Hall","full_name":"Hall, Peter","first_name":"Peter"},{"full_name":"Pietrzak, Krzysztof Z","orcid":"0000-0002-9139-1654","first_name":"Krzysztof Z","last_name":"Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87"}],"publication_status":"published","date_updated":"2025-09-09T13:06:18Z","scopus_import":"1","status":"public","title":"Random oracle combiners: Breaking the concatenation barrier for collision-resistance","_id":"14428","publication":"43rd Annual International Cryptology Conference","language":[{"iso":"eng"}]},{"date_updated":"2025-04-15T06:36:40Z","publication_status":"published","author":[{"last_name":"He","full_name":"He, Ren","first_name":"Ren"},{"full_name":"Yang, Linlin","first_name":"Linlin","last_name":"Yang"},{"full_name":"Zhang, Yu","first_name":"Yu","last_name":"Zhang"},{"full_name":"Jiang, Daochuan","first_name":"Daochuan","last_name":"Jiang"},{"full_name":"Lee, Seungho","orcid":"0000-0002-6962-8598","first_name":"Seungho","last_name":"Lee","id":"BB243B88-D767-11E9-B658-BC13E6697425"},{"last_name":"Horta","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona","full_name":"Horta, Sharona"},{"last_name":"Liang","first_name":"Zhifu","full_name":"Liang, Zhifu"},{"full_name":"Lu, Xuan","first_name":"Xuan","last_name":"Lu"},{"last_name":"Ostovari Moghaddam","full_name":"Ostovari Moghaddam, Ahmad","first_name":"Ahmad"},{"last_name":"Li","first_name":"Junshan","full_name":"Li, Junshan"},{"last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","first_name":"Maria","full_name":"Ibáñez, Maria"},{"first_name":"Ying","full_name":"Xu, Ying","last_name":"Xu"},{"full_name":"Zhou, Yingtang","first_name":"Yingtang","last_name":"Zhou"},{"last_name":"Cabot","first_name":"Andreu","full_name":"Cabot, Andreu"}],"month":"11","language":[{"iso":"eng"}],"publication":"Advanced Materials","_id":"14434","title":"A 3d‐4d‐5d high entropy alloy as a bifunctional oxygen catalyst for robust aqueous zinc–air batteries","status":"public","scopus_import":"1","article_type":"original","external_id":{"isi":["001083876900001"],"pmid":["37487245"]},"date_created":"2023-10-17T10:52:23Z","oa_version":"None","abstract":[{"lang":"eng","text":"High entropy alloys (HEAs) are highly suitable candidate catalysts for oxygen evolution and reduction reactions (OER/ORR) as they offer numerous parameters for optimizing the electronic structure and catalytic sites. Herein, FeCoNiMoW HEA nanoparticles are synthesized using a solution‐based low‐temperature approach. Such FeCoNiMoW nanoparticles show high entropy properties, subtle lattice distortions, and modulated electronic structure, leading to superior OER performance with an overpotential of 233 mV at 10 mA cm−2 and 276 mV at 100 mA cm−2. Density functional theory calculations reveal the electronic structures of the FeCoNiMoW active sites with an optimized d‐band center position that enables suitable adsorption of OOH* intermediates and reduces the Gibbs free energy barrier in the OER process. Aqueous zinc–air batteries (ZABs) based on this HEA demonstrate a high open circuit potential of 1.59 V, a peak power density of 116.9 mW cm−2, a specific capacity of 857 mAh gZn−1, and excellent stability for over 660 h of continuous charge–discharge cycles. Flexible and solid ZABs are also assembled and tested, displaying excellent charge–discharge performance at different bending angles. This work shows the significance of 4d/5d metal‐modulated electronic structure and optimized adsorption ability to improve the performance of OER/ORR, ZABs, and beyond."}],"volume":35,"isi":1,"project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"year":"2023","quality_controlled":"1","day":"16","intvolume":" 35","date_published":"2023-11-16T00:00:00Z","citation":{"ista":"He R, Yang L, Zhang Y, Jiang D, Lee S, Horta S, Liang Z, Lu X, Ostovari Moghaddam A, Li J, Ibáñez M, Xu Y, Zhou Y, Cabot A. 2023. A 3d‐4d‐5d high entropy alloy as a bifunctional oxygen catalyst for robust aqueous zinc–air batteries. Advanced Materials. 35(46), 2303719.","ieee":"R. He et al., “A 3d‐4d‐5d high entropy alloy as a bifunctional oxygen catalyst for robust aqueous zinc–air batteries,” Advanced Materials, vol. 35, no. 46. Wiley, 2023.","chicago":"He, Ren, Linlin Yang, Yu Zhang, Daochuan Jiang, Seungho Lee, Sharona Horta, Zhifu Liang, et al. “A 3d‐4d‐5d High Entropy Alloy as a Bifunctional Oxygen Catalyst for Robust Aqueous Zinc–Air Batteries.” Advanced Materials. Wiley, 2023. https://doi.org/10.1002/adma.202303719.","apa":"He, R., Yang, L., Zhang, Y., Jiang, D., Lee, S., Horta, S., … Cabot, A. (2023). A 3d‐4d‐5d high entropy alloy as a bifunctional oxygen catalyst for robust aqueous zinc–air batteries. Advanced Materials. Wiley. https://doi.org/10.1002/adma.202303719","mla":"He, Ren, et al. “A 3d‐4d‐5d High Entropy Alloy as a Bifunctional Oxygen Catalyst for Robust Aqueous Zinc–Air Batteries.” Advanced Materials, vol. 35, no. 46, 2303719, Wiley, 2023, doi:10.1002/adma.202303719.","short":"R. He, L. Yang, Y. Zhang, D. Jiang, S. Lee, S. Horta, Z. Liang, X. Lu, A. Ostovari Moghaddam, J. Li, M. Ibáñez, Y. Xu, Y. Zhou, A. Cabot, Advanced Materials 35 (2023).","ama":"He R, Yang L, Zhang Y, et al. A 3d‐4d‐5d high entropy alloy as a bifunctional oxygen catalyst for robust aqueous zinc–air batteries. Advanced Materials. 2023;35(46). doi:10.1002/adma.202303719"},"department":[{"_id":"MaIb"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"46","publisher":"Wiley","article_processing_charge":"No","publication_identifier":{"issn":["0935-9648"],"eissn":["1521-4095"]},"keyword":["Mechanical Engineering","Mechanics of Materials","General Materials Science"],"article_number":"2303719","acknowledgement":"The authors acknowledge funding from Generalitat de Catalunya 2021 SGR 01581; the project COMBENERGY, PID2019-105490RB-C32, from the Spanish Ministerio de Ciencia e Innovación; the National Natural Science Foundation of China (22102002); the Anhui Provincial Natural Science Foundation (2108085QE192); Zhejiang Province key research and development project (2023C01191); the Foundation of State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering (GrantNo.2022-K31); and The Key Research and Development Program of Hebei Province (20314305D). IREC is funded by the CERCA Programme from the Generalitat de Catalunya. L.L.Y. thanks the China Scholarship Council (CSC) for the scholarship support (202008130132). This research was supported by the Scientific Service Units (SSU) of ISTA (Institute of Science and Technology Austria) through resources provided by the Electron Microscopy Facility (EMF). S.L., S.H., and M.I. acknowledge funding by ISTA and the Werner Siemens.","acknowledged_ssus":[{"_id":"EM-Fac"}],"pmid":1,"type":"journal_article","doi":"10.1002/adma.202303719"},{"type":"journal_article","file_date_updated":"2023-10-31T12:21:39Z","oa":1,"doi":"10.1007/s00220-023-04841-3","acknowledgement":"Funding from the European Union’s Horizon 2020 research and innovation programme under the ERC grant agreement No 694227 is acknowledged. Open access funding provided by Institute of Science and Technology (IST Austria).","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"corr_author":"1","publisher":"Springer Nature","department":[{"_id":"RoSe"}],"citation":{"short":"M. Brooks, R. Seiringer, Communications in Mathematical Physics 404 (2023) 287–337.","ama":"Brooks M, Seiringer R. The Fröhlich Polaron at strong coupling: Part I - The quantum correction to the classical energy. Communications in Mathematical Physics. 2023;404:287-337. doi:10.1007/s00220-023-04841-3","ista":"Brooks M, Seiringer R. 2023. The Fröhlich Polaron at strong coupling: Part I - The quantum correction to the classical energy. Communications in Mathematical Physics. 404, 287–337.","ieee":"M. Brooks and R. Seiringer, “The Fröhlich Polaron at strong coupling: Part I - The quantum correction to the classical energy,” Communications in Mathematical Physics, vol. 404. Springer Nature, pp. 287–337, 2023.","apa":"Brooks, M., & Seiringer, R. (2023). The Fröhlich Polaron at strong coupling: Part I - The quantum correction to the classical energy. Communications in Mathematical Physics. Springer Nature. https://doi.org/10.1007/s00220-023-04841-3","chicago":"Brooks, Morris, and Robert Seiringer. “The Fröhlich Polaron at Strong Coupling: Part I - The Quantum Correction to the Classical Energy.” Communications in Mathematical Physics. Springer Nature, 2023. https://doi.org/10.1007/s00220-023-04841-3.","mla":"Brooks, Morris, and Robert Seiringer. “The Fröhlich Polaron at Strong Coupling: Part I - The Quantum Correction to the Classical Energy.” Communications in Mathematical Physics, vol. 404, Springer Nature, 2023, pp. 287–337, doi:10.1007/s00220-023-04841-3."},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"issn":["0010-3616"],"eissn":["1432-0916"]},"article_processing_charge":"Yes (via OA deal)","arxiv":1,"day":"01","quality_controlled":"1","date_published":"2023-11-01T00:00:00Z","intvolume":" 404","ec_funded":1,"abstract":[{"lang":"eng","text":"We study the Fröhlich polaron model in R3, and establish the subleading term in the strong coupling asymptotics of its ground state energy, corresponding to the quantum corrections to the classical energy determined by the Pekar approximation."}],"page":"287-337","year":"2023","isi":1,"project":[{"grant_number":"694227","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","name":"Analysis of quantum many-body systems","call_identifier":"H2020"}],"volume":404,"date_created":"2023-10-22T22:01:13Z","external_id":{"arxiv":["2207.03156"],"isi":["001096217400007"]},"oa_version":"Published Version","_id":"14441","publication":"Communications in Mathematical Physics","language":[{"iso":"eng"}],"article_type":"original","status":"public","scopus_import":"1","file":[{"date_updated":"2023-10-31T12:21:39Z","success":1,"date_created":"2023-10-31T12:21:39Z","file_size":832375,"checksum":"1ae49b39247cb6b40ff75997381581b8","file_name":"2023_CommMathPhysics_Brooks.pdf","access_level":"open_access","content_type":"application/pdf","relation":"main_file","creator":"dernst","file_id":"14477"}],"title":"The Fröhlich Polaron at strong coupling: Part I - The quantum correction to the classical energy","ddc":["510"],"publication_status":"published","date_updated":"2025-09-09T13:12:02Z","month":"11","author":[{"last_name":"Brooks","id":"B7ECF9FC-AA38-11E9-AC9A-0930E6697425","full_name":"Brooks, Morris","orcid":"0000-0002-6249-0928","first_name":"Morris"},{"full_name":"Seiringer, Robert","orcid":"0000-0002-6781-0521","first_name":"Robert","last_name":"Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"}]},{"article_number":"95","acknowledgement":"MR-V and RS are supported by Fondecyt Grant No. 1220536 and Millennium Science Initiative Program NCN19_170D of ANID, Chile. P.d.C. was supported by Scholarships Nos. 2021/10139-2 and 2022/13872-5 and ICTP-SAIFR Grant No. 2021/14335-0, all granted by São Paulo Research Foundation (FAPESP), Brazil.","corr_author":"1","pmid":1,"type":"journal_article","main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2111.05952"}],"doi":"10.1140/epje/s10189-023-00354-y","oa":1,"quality_controlled":"1","arxiv":1,"day":"01","intvolume":" 46","OA_place":"repository","date_published":"2023-10-01T00:00:00Z","citation":{"short":"M.N. Rojas Vega, P. De Castro, R. Soto, The European Physical Journal E 46 (2023).","ama":"Rojas Vega MN, De Castro P, Soto R. Mixtures of self-propelled particles interacting with asymmetric obstacles. The European Physical Journal E. 2023;46(10). doi:10.1140/epje/s10189-023-00354-y","ieee":"M. N. Rojas Vega, P. De Castro, and R. Soto, “Mixtures of self-propelled particles interacting with asymmetric obstacles,” The European Physical Journal E, vol. 46, no. 10. Springer Nature, 2023.","chicago":"Rojas Vega, Mauricio Nicolas, Pablo De Castro, and Rodrigo Soto. “Mixtures of Self-Propelled Particles Interacting with Asymmetric Obstacles.” The European Physical Journal E. Springer Nature, 2023. https://doi.org/10.1140/epje/s10189-023-00354-y.","apa":"Rojas Vega, M. N., De Castro, P., & Soto, R. (2023). Mixtures of self-propelled particles interacting with asymmetric obstacles. The European Physical Journal E. Springer Nature. https://doi.org/10.1140/epje/s10189-023-00354-y","ista":"Rojas Vega MN, De Castro P, Soto R. 2023. Mixtures of self-propelled particles interacting with asymmetric obstacles. The European Physical Journal E. 46(10), 95.","mla":"Rojas Vega, Mauricio Nicolas, et al. “Mixtures of Self-Propelled Particles Interacting with Asymmetric Obstacles.” The European Physical Journal E, vol. 46, no. 10, 95, Springer Nature, 2023, doi:10.1140/epje/s10189-023-00354-y."},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"AnSa"}],"publisher":"Springer Nature","issue":"10","article_processing_charge":"No","publication_identifier":{"issn":["1292-8941"],"eissn":["1292-895X"]},"date_created":"2023-10-22T22:01:13Z","external_id":{"isi":["001187541900001"],"arxiv":["2111.05952"],"pmid":["37819444"]},"oa_version":"Preprint","abstract":[{"text":"In the presence of an obstacle, active particles condensate into a surface “wetting” layer due to persistent motion. If the obstacle is asymmetric, a rectification current arises in addition to wetting. Asymmetric geometries are therefore commonly used to concentrate microorganisms like bacteria and sperms. However, most studies neglect the fact that biological active matter is diverse, composed of individuals with distinct self-propulsions. Using simulations, we study a mixture of “fast” and “slow” active Brownian disks in two dimensions interacting with large half-disk obstacles. With this prototypical obstacle geometry, we analyze how the stationary collective behavior depends on the degree of self-propulsion “diversity,” defined as proportional to the difference between the self-propulsion speeds, while keeping the average self-propulsion speed fixed. A wetting layer rich in fast particles arises. The rectification current is amplified by speed diversity due to a superlinear dependence of rectification on self-propulsion speed, which arises from cooperative effects. Thus, the total rectification current cannot be obtained from an effective one-component active fluid with the same average self-propulsion speed, highlighting the importance of considering diversity in active matter.","lang":"eng"}],"isi":1,"volume":46,"year":"2023","date_updated":"2025-09-09T13:08:14Z","publication_status":"published","OA_type":"green","author":[{"first_name":"Mauricio Nicolas","full_name":"Rojas Vega, Mauricio Nicolas","id":"441e7207-f91f-11ec-b67c-9e6fe3d8fd6d","last_name":"Rojas Vega"},{"last_name":"De Castro","first_name":"Pablo","full_name":"De Castro, Pablo"},{"first_name":"Rodrigo","full_name":"Soto, Rodrigo","last_name":"Soto"}],"month":"10","publication":"The European Physical Journal E","language":[{"iso":"eng"}],"_id":"14442","title":"Mixtures of self-propelled particles interacting with asymmetric obstacles","scopus_import":"1","status":"public","article_type":"original"}]