[{"_id":"21849","oa_version":"Published Version","quality_controlled":"1","department":[{"_id":"EdHa"}],"scopus_import":"1","volume":22,"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"doi":"10.1038/s41567-026-03263-x","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"apa":"Olmeda, F., Lohoff, T., Kafetzopoulos, I., Clark, S. J., Benson, L., Santos, F., … Rulands, S. (2026). Scaling and self-similarity in the formation of the embryonic epigenome. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-026-03263-x","ista":"Olmeda F, Lohoff T, Kafetzopoulos I, Clark SJ, Benson L, Santos F, Krueger F, Walker S, Reik W, Rulands S. 2026. Scaling and self-similarity in the formation of the embryonic epigenome. Nature Physics. 22, 931–940.","ama":"Olmeda F, Lohoff T, Kafetzopoulos I, et al. Scaling and self-similarity in the formation of the embryonic epigenome. Nature Physics. 2026;22:931-940. doi:10.1038/s41567-026-03263-x","mla":"Olmeda, Fabrizio, et al. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” Nature Physics, vol. 22, Springer Nature, 2026, pp. 931–40, doi:10.1038/s41567-026-03263-x.","ieee":"F. Olmeda et al., “Scaling and self-similarity in the formation of the embryonic epigenome,” Nature Physics, vol. 22. Springer Nature, pp. 931–940, 2026.","short":"F. Olmeda, T. Lohoff, I. Kafetzopoulos, S.J. Clark, L. Benson, F. Santos, F. Krueger, S. Walker, W. Reik, S. Rulands, Nature Physics 22 (2026) 931–940.","chicago":"Olmeda, Fabrizio, Tim Lohoff, Ioannis Kafetzopoulos, Stephen J. Clark, Laura Benson, Fatima Santos, Felix Krueger, Simon Walker, Wolf Reik, and Steffen Rulands. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” Nature Physics. Springer Nature, 2026. https://doi.org/10.1038/s41567-026-03263-x."},"dataavailabilitystatement":"All sequencing datasets reported in this paper are available on Gene Expression Omnibus (GEO) under accession GSE166226. STORM localization data are available on Zenodo (https://doi.org/10.5281/zenodo.18965309)57. Raw images are available upon request. Code for computing the correlation functions and STORM analysis are available via GitHub at https://github.com/srulands/inference_of_spatio-temporal_processes.","author":[{"last_name":"Olmeda","first_name":"Fabrizio","id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","full_name":"Olmeda, Fabrizio"},{"full_name":"Lohoff, Tim","last_name":"Lohoff","first_name":"Tim"},{"first_name":"Ioannis","last_name":"Kafetzopoulos","full_name":"Kafetzopoulos, Ioannis"},{"last_name":"Clark","first_name":"Stephen J.","full_name":"Clark, Stephen J."},{"full_name":"Benson, Laura","first_name":"Laura","last_name":"Benson"},{"full_name":"Santos, Fatima","first_name":"Fatima","last_name":"Santos"},{"full_name":"Krueger, Felix","first_name":"Felix","last_name":"Krueger"},{"full_name":"Walker, Simon","last_name":"Walker","first_name":"Simon"},{"full_name":"Reik, Wolf","last_name":"Reik","first_name":"Wolf"},{"last_name":"Rulands","first_name":"Steffen","full_name":"Rulands, Steffen"}],"date_updated":"2026-07-27T13:56:09Z","title":"Scaling and self-similarity in the formation of the embryonic epigenome","researchdata_availability":"yes","article_type":"original","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"file_date_updated":"2026-07-27T13:54:58Z","acknowledgement":"We thank all members of the W.R. and S.R. laboratories, F. Piazza, B. D. Simons, and F. Jülicher for helpful discussions. We thank M. Ciarchi for providing annotations for the chromatin compartments. S.R. is a member of the Center for Nano Science (CeNS). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement number 950349). Research in W.R.’s laboratory was supported by the Biotechnology and Biological Sciences Research Council (BB/K010867/1), Wellcome (095645/Z/11/Z) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (EpiCell lineage 882798). F.O. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413. Open access funding provided by Max Planck Society.","day":"01","license":"https://creativecommons.org/licenses/by/4.0/","OA_place":"publisher","external_id":{"pmid":["42318073"]},"das_tickbox":"1","publication":"Nature Physics","ddc":["570"],"status":"public","month":"06","date_created":"2026-05-10T22:02:16Z","has_accepted_license":"1","abstract":[{"text":"The development of complex tissues relies on the precise assignment of cell identity. At the molecular scale, this process depends on the deposition of epigenetic modifications—such as methylation—that are regulated by complex biochemical networks and occur at specific regions on the DNA and chromatin. Here we show that despite the complexity of epigenetic regulation, dynamical scaling and self-similarity of DNA methylation marks emerge in embryonic development. Drawing on single-cell multi-omics experiments, super-resolution microscopy and statistical physics, we demonstrate that these phenomena originate in dynamical feedback between DNA methylation and the formation of nanoscale dynamic chromatin aggregates. These nanoscale processes lead to genome-wide increase in DNA methylation marks following a power law and self-similar correlation functions. Using this framework, we identify methylation patterns that precede gene expression changes in embryonic symmetry breaking. Our work identifies linear sequencing measurements as a laboratory to study mesoscopic biophysical processes in vivo.","lang":"eng"}],"pmid":1,"publisher":"Springer Nature","supplementarymaterial":"yes","OA_type":"hybrid","language":[{"iso":"eng"}],"PlanS_conform":"1","intvolume":" 22","year":"2026","article_processing_charge":"Yes (via OA deal)","publication_status":"published","file":[{"date_updated":"2026-07-27T13:54:58Z","file_id":"22591","success":1,"file_size":7932222,"access_level":"open_access","content_type":"application/pdf","date_created":"2026-07-27T13:54:58Z","relation":"main_file","checksum":"58e7734f1ebaf6def642140cb489f08f","creator":"dernst","file_name":"2026_NaturePhysics_Olmeda.pdf"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-06-01T00:00:00Z","page":"931-940","ec_funded":1,"type":"journal_article","oa":1},{"das_tickbox":"0","acknowledged_ssus":[{"_id":"Bio"},{"_id":"M-Shop"}],"month":"06","status":"public","ddc":["600"],"corr_author":"1","publication":"Journal of Microscopy","issue":"3","language":[{"iso":"eng"}],"OA_type":"hybrid","PlanS_conform":"1","intvolume":" 302","abstract":[{"lang":"eng","text":"Three-dimensional (3D) printing has rapidly developed from a niche hobbyist activity into a widely accessible and indispensable technology across multiple scientific disciplines. Within microscopy, optical engineering laboratories and imaging core facilities, 3D printing enables creating customised solutions for sample holders, optical components and everyday laboratory tools that traditionally required specialised machining. By providing rapid prototyping, low-cost production and reproducibility, 3D printing facilitates innovation and efficiency in facility operations. This article provides a perspective on the possibilities, challenges, and practical aspects of implementing 3D printing within microscopy core facilities. Instead of providing technical review about 3D printing, we focus on service organisation, user engagement, resource management and community-driven repositories for design dissemination. Our aim is to share insights with those considering the implementation of 3D printing as a service for developing add-on components to ease the operation of different aspects of the machine-park driven services and those who are managing advanced instrumentation within research groups."}],"has_accepted_license":"1","pmid":1,"date_created":"2026-05-17T22:02:11Z","supplementarymaterial":"no","publisher":"Wiley","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-06-01T00:00:00Z","year":"2026","article_processing_charge":"Yes (via OA deal)","publication_status":"published","file":[{"file_id":"22593","success":1,"date_updated":"2026-07-27T14:01:34Z","relation":"main_file","date_created":"2026-07-27T14:01:34Z","checksum":"06dfad92b1465ed614a1201b4129960a","creator":"dernst","file_name":"2026_JourMicroscopy_Goudarzi.pdf","file_size":4625767,"content_type":"application/pdf","access_level":"open_access"}],"type":"journal_article","oa":1,"page":"382-395","_id":"21883","quality_controlled":"1","oa_version":"Published Version","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"chicago":"Goudarzi, Mohammad, Maximilian Schuster, Arthur Milberger, Manuel Gunkel, Stefan Terjung, and Gabriel Krens. “3D Printing in Core Facilities – Low Pain, High Gain.” Journal of Microscopy. Wiley, 2026. https://doi.org/10.1111/jmi.70106.","short":"M. Goudarzi, M. Schuster, A. Milberger, M. Gunkel, S. Terjung, G. Krens, Journal of Microscopy 302 (2026) 382–395.","ieee":"M. Goudarzi, M. Schuster, A. Milberger, M. Gunkel, S. Terjung, and G. Krens, “3D printing in core facilities – Low pain, high gain,” Journal of Microscopy, vol. 302, no. 3. Wiley, pp. 382–395, 2026.","mla":"Goudarzi, Mohammad, et al. “3D Printing in Core Facilities – Low Pain, High Gain.” Journal of Microscopy, vol. 302, no. 3, Wiley, 2026, pp. 382–95, doi:10.1111/jmi.70106.","apa":"Goudarzi, M., Schuster, M., Milberger, A., Gunkel, M., Terjung, S., & Krens, G. (2026). 3D printing in core facilities – Low pain, high gain. Journal of Microscopy. Wiley. https://doi.org/10.1111/jmi.70106","ama":"Goudarzi M, Schuster M, Milberger A, Gunkel M, Terjung S, Krens G. 3D printing in core facilities – Low pain, high gain. Journal of Microscopy. 2026;302(3):382-395. doi:10.1111/jmi.70106","ista":"Goudarzi M, Schuster M, Milberger A, Gunkel M, Terjung S, Krens G. 2026. 3D printing in core facilities – Low pain, high gain. Journal of Microscopy. 302(3), 382–395."},"doi":"10.1111/jmi.70106","department":[{"_id":"Bio"}],"scopus_import":"1","volume":302,"date_updated":"2026-07-27T14:02:46Z","title":"3D printing in core facilities – Low pain, high gain","researchdata_availability":"no","author":[{"first_name":"Mohammad","last_name":"Goudarzi","full_name":"Goudarzi, Mohammad","id":"3384113A-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Schuster","first_name":"Maximilian","id":"37e65def-d415-11eb-ae59-a7b67be103db","full_name":"Schuster, Maximilian"},{"full_name":"Milberger, Arthur","first_name":"Arthur","last_name":"Milberger"},{"first_name":"Manuel","last_name":"Gunkel","full_name":"Gunkel, Manuel"},{"full_name":"Terjung, Stefan","last_name":"Terjung","first_name":"Stefan"},{"full_name":"Krens, Gabriel","id":"2B819732-F248-11E8-B48F-1D18A9856A87","last_name":"Krens","orcid":"0000-0003-4761-5996","first_name":"Gabriel"}],"OA_place":"publisher","external_id":{"pmid":["42104760"]},"article_type":"original","publication_identifier":{"issn":["0022-2720"],"eissn":["1365-2818"]},"acknowledgement":"This work was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Imaging & Optics Facility (IOF) and the MiBa Machine Shop. Specifically; Robert Hauschild (IOF), sharing designs, insights and pioneering 3D printing activities at the Imaging and Optics Facility; Bernhard Hochreiter (IOF), for support and testing of anoxic chamber. We also thank Ana Rita Carvalho Faria and Oliver Biehlmaier (Biozentrum University of Basel, Imaging Core Facility) for sharing the design of the adopted power meter.\r\nOpen Access funding provided by Institute of Science and Technology Austria.","file_date_updated":"2026-07-27T14:01:34Z","day":"01"},{"abstract":[{"lang":"eng","text":"Magneto-optic Kerr effect (MOKE) is a powerful probe of broken time-reversal symmetry (T), typically used to study ferromagnets. While MOKE has been observed in some antiferromagnets (AFMs) with vanishing magnetization, it is often associated with structures whose symmetry is lower than basic collinear, bipartite order. In contrast, theory predicts a mechanism for MOKE intrinsic to all AFMs of A-type, i.e. layered AFMs in which ferromagnetic layers are antiferromagnetically aligned. Here we report the experimental confirmation of this mechanism in a bulk AFM. We achieve this by measuring the imaginary component of MOKE as a function of photon energy in MnBi2Te4, an A-type AFM where T is preserved in combination with a translation, and comparing the experimental results with model calculations. Our model suggests that observable MOKE should be expected in all collinear A-type AFMs with out-of-plane spin order, thus enabling optical detection of AFM domains and expanding the scope of MOKE to few-layer AFMs."}],"date_created":"2026-05-12T21:31:27Z","has_accepted_license":"1","publisher":"Springer Nature","supplementarymaterial":"yes","language":[{"iso":"eng"}],"OA_type":"gold","intvolume":" 17","PlanS_conform":"1","das_tickbox":"1","status":"public","month":"07","publication":"Nature Communications","corr_author":"1","ddc":["530"],"type":"journal_article","oa":1,"publication_status":"published","year":"2026","article_processing_charge":"Yes","file":[{"success":1,"file_id":"22592","date_updated":"2026-07-27T13:58:06Z","file_name":"2026_NatureComm_Sunko.pdf","checksum":"bde19c4342933c05fe801c2bef7dc732","creator":"dernst","relation":"main_file","date_created":"2026-07-27T13:58:06Z","content_type":"application/pdf","access_level":"open_access","file_size":1054779}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-07-27T00:00:00Z","article_number":"7364","department":[{"_id":"VeSu"}],"scopus_import":"1","volume":17,"doi":"10.1038/s41467-026-72577-4","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"chicago":"Sunko, Veronika, Salman Ahsanullah, Vivek Jain, Sophie Weber, Sivaloganathan Kumaran, Jiaqiang Yan, Joseph Orenstein, and Dmitry Ovchinnikov. “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.” Nature Communications. Springer Nature, 2026. https://doi.org/10.1038/s41467-026-72577-4.","short":"V. Sunko, S. Ahsanullah, V. Jain, S. Weber, S. Kumaran, J. Yan, J. Orenstein, D. Ovchinnikov, Nature Communications 17 (2026).","ieee":"V. Sunko et al., “Magneto-optical Kerr effect in an A-type antiferromagnet,” Nature Communications, vol. 17. Springer Nature, 2026.","mla":"Sunko, Veronika, et al. “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.” Nature Communications, vol. 17, 7364, Springer Nature, 2026, doi:10.1038/s41467-026-72577-4.","ama":"Sunko V, Ahsanullah S, Jain V, et al. Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications. 2026;17. doi:10.1038/s41467-026-72577-4","ista":"Sunko V, Ahsanullah S, Jain V, Weber S, Kumaran S, Yan J, Orenstein J, Ovchinnikov D. 2026. Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications. 17, 7364.","apa":"Sunko, V., Ahsanullah, S., Jain, V., Weber, S., Kumaran, S., Yan, J., … Ovchinnikov, D. (2026). Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-026-72577-4"},"_id":"21872","oa_version":"Published Version","quality_controlled":"1","day":"27","file_date_updated":"2026-07-27T13:58:06Z","related_material":{"record":[{"status":"public","id":"21422","relation":"research_data"}]},"acknowledgement":"We thank Christine Kuntscher for providing optical conductivity and reflectance data published in ref. 33, and Nicola Spaldin, Joel Moore and Bevin Huang for useful discussions. V.S. and J.O. received support from the Gordon and Betty Moore Foundation’s EPiQS Initiative through Grant GBMF4537 awarded to J.O. at UC Berkeley. Experimental and theoretical work at LBNL and UC Berkeley was funded by the Quantum Materials (KC2202) program under the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division under Contract No. DE-AC02-05CH11231. Work at the University of Kansas was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, EPSCoR, and Materials Sciences and Engineering Division under Award No. DE-SC0025319. Parts of device fabrication were performed in the KU Nanofabrication Facility, which is supported by the National Institutes of Health NIGMS P30GM145499. Work at ORNL was supported by the U. S. Department of Energy, Office of Science, Basic Energy Sciences, Materials Sciences and Engineering Division. For the DFT calculations we used resources provided by the Swedish National Infrastructure for Computing (SNIC) at C3SE. We acknowledge support from the US National Science Foundation (NSF) Grant Number 2201516 under the Accelnet program of Office of International Science and Engineering (OISE). This publication is funded in part by a QuantEmX grant from ICAM and the Gordon and Betty Moore Foundation through Grant GBMF9616 to S. K.","article_type":"original","publication_identifier":{"eissn":["2041-1723"]},"DOAJ_listed":"1","arxiv":1,"OA_place":"publisher","external_id":{"arxiv":["2504.16167"]},"author":[{"full_name":"Sunko, Veronika","id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3","first_name":"Veronika","last_name":"Sunko","orcid":"0000-0003-2724-3523"},{"full_name":"Ahsanullah, Salman","first_name":"Salman","last_name":"Ahsanullah"},{"last_name":"Jain","first_name":"Vivek","full_name":"Jain, Vivek"},{"full_name":"Weber, Sophie","last_name":"Weber","first_name":"Sophie"},{"first_name":"Sivaloganathan","last_name":"Kumaran","full_name":"Kumaran, Sivaloganathan"},{"first_name":"Jiaqiang","last_name":"Yan","full_name":"Yan, Jiaqiang"},{"last_name":"Orenstein","first_name":"Joseph","full_name":"Orenstein, Joseph"},{"full_name":"Ovchinnikov, Dmitry","last_name":"Ovchinnikov","first_name":"Dmitry"}],"dataavailabilitystatement":"The datasets generated and analyzed during the study of “Magneto-optical Kerr effect in an A-type antiferromagnet\" are available in the ISTA REx repository with https://doi.org/10.15479/AT-ISTA-21422.","researchdata_availability":"yes","title":"Magneto-optical Kerr effect in an A-type antiferromagnet","date_updated":"2026-07-27T13:59:27Z"},{"article_processing_charge":"No","year":"2026","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-07-01T00:00:00Z","page":"226-235","type":"journal_article","issue":"4","das_tickbox":"1","publication":"Alternatives to Laboratory Animals","status":"public","month":"07","corr_author":"1","date_created":"2026-06-07T22:01:36Z","pmid":1,"abstract":[{"lang":"eng","text":"One Health initiatives are modern paradigms for research and health care practices in various fields. Concrete definitions of the One Health framework, however, remain heterogeneous, leading to conceptual problems and uncertainties in the application of the framework. This article discusses several approaches to the One Health concept, and their associated consequences, with special focus on animal experimentation. The first issue addressed is how One Health should be defined, as well as what (and who) should be considered within a One Health approach. In order to shed further light on this, we explore the history of animals in biomedical science, highlighting historical milestones in the use of animal models, as well as the development and current state of ethical considerations in the field of animal experimentation. The second issue comes with the inclusion of animal experimentation per se as part of the One Health concept. Therefore, particular attention is paid to bioethical principles and the resulting problems that can arise when applying them to the One Health concept. Arguments such as the idea of inequality between humans and non-human animals, and the premise that all actions are done for the benefit of humans, are raised and then used to explore the question of whether the One Health concept is compatible with existing bioethical principles. Based on the bioethical principles of protecting the environment, the biodiversity and biosphere, this paper seeks an inclusive perspective of the One Health concept. Successful solutions will be based on this concept, which embraces all living beings. The authors conclude that a multispecies ethics approach could help create a more ethical ecosystem that is aligned with the wellbeing of all life on a shared planet."}],"publisher":"SAGE Publications","language":[{"iso":"eng"}],"OA_type":"closed access","intvolume":" 54","author":[{"full_name":"Ulman, Yesim Isil","first_name":"Yesim Isil","last_name":"Ulman"},{"first_name":"Nikos","last_name":"Kostomitsopoulos","full_name":"Kostomitsopoulos, Nikos"},{"last_name":"Camenzind","first_name":"Samuel","full_name":"Camenzind, Samuel"},{"first_name":"Maria","last_name":"Kitsara","full_name":"Kitsara, Maria"},{"full_name":"Pavone, Ilja Richard","first_name":"Ilja Richard","last_name":"Pavone"},{"last_name":"Schober","first_name":"Sophie","full_name":"Schober, Sophie","id":"80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8"}],"date_updated":"2026-07-27T14:13:17Z","title":"Emerging bioethical conflicts: One Health and animal experimentation","publication_identifier":{"issn":["0261-1929"],"eissn":["2632-3559"]},"article_type":"original","day":"01","external_id":{"pmid":["42185081"]},"_id":"21950","oa_version":"None","quality_controlled":"1","department":[{"_id":"PreCl"}],"scopus_import":"1","volume":54,"citation":{"short":"Y.I. Ulman, N. Kostomitsopoulos, S. Camenzind, M. Kitsara, I.R. Pavone, S. Schober, Alternatives to Laboratory Animals 54 (2026) 226–235.","chicago":"Ulman, Yesim Isil, Nikos Kostomitsopoulos, Samuel Camenzind, Maria Kitsara, Ilja Richard Pavone, and Sophie Schober. “Emerging Bioethical Conflicts: One Health and Animal Experimentation.” Alternatives to Laboratory Animals. SAGE Publications, 2026. https://doi.org/10.1177/02611929261453330.","ista":"Ulman YI, Kostomitsopoulos N, Camenzind S, Kitsara M, Pavone IR, Schober S. 2026. Emerging bioethical conflicts: One Health and animal experimentation. Alternatives to Laboratory Animals. 54(4), 226–235.","ama":"Ulman YI, Kostomitsopoulos N, Camenzind S, Kitsara M, Pavone IR, Schober S. Emerging bioethical conflicts: One Health and animal experimentation. Alternatives to Laboratory Animals. 2026;54(4):226-235. doi:10.1177/02611929261453330","apa":"Ulman, Y. I., Kostomitsopoulos, N., Camenzind, S., Kitsara, M., Pavone, I. R., & Schober, S. (2026). Emerging bioethical conflicts: One Health and animal experimentation. Alternatives to Laboratory Animals. SAGE Publications. https://doi.org/10.1177/02611929261453330","ieee":"Y. I. Ulman, N. Kostomitsopoulos, S. Camenzind, M. Kitsara, I. R. Pavone, and S. Schober, “Emerging bioethical conflicts: One Health and animal experimentation,” Alternatives to Laboratory Animals, vol. 54, no. 4. SAGE Publications, pp. 226–235, 2026.","mla":"Ulman, Yesim Isil, et al. “Emerging Bioethical Conflicts: One Health and Animal Experimentation.” Alternatives to Laboratory Animals, vol. 54, no. 4, SAGE Publications, 2026, pp. 226–35, doi:10.1177/02611929261453330."},"doi":"10.1177/02611929261453330"},{"corr_author":"1","publication":"Nature Ecology & Evolution","month":"06","status":"public","das_tickbox":"0","intvolume":" 10","language":[{"iso":"eng"}],"OA_type":"closed access","supplementarymaterial":"no","publisher":"Springer Nature","abstract":[{"text":"Individually silencing 125 fruit fly genes reveals opposing fitness effects of mutations between females and males, as well as between germline and somatic tissues.","lang":"eng"}],"pmid":1,"date_created":"2026-05-20T14:36:45Z","date_published":"2026-06-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","article_processing_charge":"No","publication_status":"published","type":"journal_article","page":"1035-1036","quality_controlled":"1","oa_version":"None","_id":"21900","citation":{"ieee":"F. Ruzicka, “Reverse genetics of sexual antagonism,” Nature Ecology & Evolution, vol. 10. Springer Nature, pp. 1035–1036, 2026.","mla":"Ruzicka, Filip. “Reverse Genetics of Sexual Antagonism.” Nature Ecology & Evolution, vol. 10, Springer Nature, 2026, pp. 1035–36, doi:10.1038/s41559-026-03036-y.","apa":"Ruzicka, F. (2026). Reverse genetics of sexual antagonism. Nature Ecology & Evolution. Springer Nature. https://doi.org/10.1038/s41559-026-03036-y","ista":"Ruzicka F. 2026. Reverse genetics of sexual antagonism. Nature Ecology & Evolution. 10, 1035–1036.","ama":"Ruzicka F. Reverse genetics of sexual antagonism. Nature Ecology & Evolution. 2026;10:1035-1036. doi:10.1038/s41559-026-03036-y","chicago":"Ruzicka, Filip. “Reverse Genetics of Sexual Antagonism.” Nature Ecology & Evolution. Springer Nature, 2026. https://doi.org/10.1038/s41559-026-03036-y.","short":"F. Ruzicka, Nature Ecology & Evolution 10 (2026) 1035–1036."},"doi":"10.1038/s41559-026-03036-y","volume":10,"scopus_import":"1","department":[{"_id":"BeVi"}],"date_updated":"2026-07-27T14:05:02Z","title":"Reverse genetics of sexual antagonism","researchdata_availability":"no","author":[{"first_name":"Filip","last_name":"Ruzicka","id":"347955dd-57b0-11ee-9095-c28bdd368f4b","full_name":"Ruzicka, Filip"}],"external_id":{"pmid":["42067637 "]},"article_type":"comment","publication_identifier":{"eissn":["2397-334X"]},"day":"01"},{"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"short":"J. Zapata, Overcoming Degeneracy and Singularity: Techniques for Semidefinite Programs and Homotopy Continuation Endgames, Institute of Science and Technology Austria, 2026.","chicago":"Zapata, Jeferson. “Overcoming Degeneracy and Singularity: Techniques for Semidefinite Programs and Homotopy Continuation Endgames.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21957.","apa":"Zapata, J. (2026). Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21957","ama":"Zapata J. Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames. 2026. doi:10.15479/AT-ISTA-21957","ista":"Zapata J. 2026. Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames. Institute of Science and Technology Austria.","ieee":"J. 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In the first part, we present a hybrid symbolic-numeric algorithm for certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating linear matrix inequalities (LMIs) into a structured polynomial system via facial reduction and incidence varieties, we guarantee the existence of an isolated exact solution. This algebraic reduction enables the certification of maximum-rank numerical approximations using methods from algebraic geometry.\r\n\r\nIn the second part, we address the severe ill-conditioning and loss of quadratic convergence that plague standard path-tracking methods near isolated singular roots. To overcome this, we propose tracking algorithms that achieve superlinear convergence without the computational bloat characteristic of classical deflation techniques. By modeling the solution path as a generalized fractional Puiseux series, our approach combines an explicitly derived algebraic predictor with a localized hyperplane desingularization phase during the corrector step. Furthermore, we introduce a continuous path-limit method and an extension of the geometric sequence rule to directly extract exact fractional exponents. This bypasses traditional heuristic trial-and-error methods and explicitly accommodates sparse series expansions. Numerical experiments confirm that our method significantly reduces the cumulative number of matrix inversions while achieving high-accuracy root approximations, even for heavily degenerate systems exhibiting higher coranks.","lang":"eng"}],"alternative_title":["ISTA Thesis"],"supervisor":[{"id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","full_name":"Kolmogorov, Vladimir","last_name":"Kolmogorov","first_name":"Vladimir"}],"language":[{"iso":"eng"}],"degree_awarded":"PhD","ddc":["500"],"status":"public","month":"06","corr_author":"1","das_tickbox":"1","page":"89","oa":1,"type":"dissertation","file":[{"file_size":40811933,"content_type":"application/zip","access_level":"closed","relation":"source_file","date_created":"2026-06-08T13:20:02Z","file_name":"istaustriathesis_JZapata.zip","creator":"jzapata","checksum":"b11a959e99d3dcf61040282b5c837141","date_updated":"2026-06-08T13:20:02Z","file_id":"21958"},{"checksum":"edf1e5899b2e31505cd1aa3fe8bd4b7f","creator":"jzapata","file_name":"4_Final_Thesis_JZapata_REX.pdf","relation":"main_file","date_created":"2026-06-10T13:33:25Z","content_type":"application/pdf","access_level":"open_access","file_size":2207892,"file_id":"21992","success":1,"date_updated":"2026-06-10T13:33:25Z"}],"publication_status":"published","year":"2026","article_processing_charge":"No","date_published":"2026-06-09T00:00:00Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"},{"page":"185","type":"dissertation","article_processing_charge":"No","year":"2026","publication_status":"published","file":[{"file_id":"21386","date_updated":"2026-03-02T10:59:50Z","date_created":"2026-03-02T10:59:50Z","relation":"source_file","creator":"sriegler","file_name":"2026_Riegler_Stefan_Thesis.zip","checksum":"2f1f44e8536c2538f94a440217452c9f","file_size":31430022,"access_level":"closed","content_type":"application/x-zip-compressed"},{"file_name":"2026_Riegler_Stefan_Thesis.pdf","creator":"sriegler","checksum":"2e8dc39640bc26ae5684c944c619719b","relation":"main_file","date_created":"2026-03-02T10:59:49Z","content_type":"application/pdf","access_level":"closed","file_size":11635090,"file_id":"21387","embargo":"2027-02-27","date_updated":"2026-03-02T10:59:49Z","embargo_to":"open_access"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2026-02-26T00:00:00Z","alternative_title":["ISTA Thesis"],"has_accepted_license":"1","date_created":"2026-02-27T09:08:14Z","publisher":"Institute of Science and Technology Austria","language":[{"iso":"eng"}],"supervisor":[{"orcid":"0000-0002-8510-9739","last_name":"Benková","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva"}],"degree_awarded":"PhD","das_tickbox":"1","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"status":"public","ddc":["570","575","583"],"month":"02","corr_author":"1","related_material":{"record":[{"status":"public","relation":"research_data","id":"21363"}]},"file_date_updated":"2026-03-02T10:59:50Z","publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"I would like to acknowledge the Austrian Academy of Sciences (ÖAW) and European\r\nResearch Executive Agency (REA) for funding my research (DOC ÖAW Fellowship\r\n26130, Horizon Europe BOLERO Project 101060393). ","day":"26","license":"https://creativecommons.org/licenses/by-sa/4.0/","OA_place":"repository","author":[{"id":"FF6018E0-D806-11E9-8E43-0B14E6697425","full_name":"Riegler, Stefan","orcid":"0000-0003-3413-1343","last_name":"Riegler","first_name":"Stefan"}],"date_updated":"2026-07-27T14:30:08Z","title":"Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"project":[{"name":"Breeding for coffee and cocoa root resilience in low input farming systems based on improved rootstocks","grant_number":"101060393","_id":"34afa094-11ca-11ed-8bc3-a375845a59fb"}],"tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png"},"citation":{"short":"S. Riegler, Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species, Institute of Science and Technology Austria, 2026.","chicago":"Riegler, Stefan. “Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21360.","apa":"Riegler, S. (2026). Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21360","ista":"Riegler S. 2026. Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. Institute of Science and Technology Austria.","ama":"Riegler S. Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. 2026. doi:10.15479/AT-ISTA-21360","ieee":"S. Riegler, “Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species,” Institute of Science and Technology Austria, 2026.","mla":"Riegler, Stefan. Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21360."},"doi":"10.15479/AT-ISTA-21360","_id":"21360","oa_version":"Published Version","doi_confirm":"1"},{"contributor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","contributor_type":"supervisor","first_name":"Eva","last_name":"Benková","orcid":"0000-0002-8510-9739"}],"type":"research_data","day":"27","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"21360"}]},"file_date_updated":"2026-02-27T09:13:11Z","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","title":"Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species","date_updated":"2026-07-27T14:30:07Z","date_published":"2026-02-27T00:00:00Z","year":"2026","article_processing_charge":"No","author":[{"first_name":"Stefan","last_name":"Riegler","orcid":"0000-0003-3413-1343","full_name":"Riegler, Stefan","id":"FF6018E0-D806-11E9-8E43-0B14E6697425"}],"file":[{"embargo_to":"open_access","date_updated":"2026-02-27T09:11:33Z","embargo":"2027-02-27","file_id":"21364","file_size":63749444,"content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","access_level":"closed","relation":"main_file","date_created":"2026-02-27T09:11:33Z","creator":"sriegler","file_name":"SupplementaryTables.xlsx","checksum":"de9145fa166a28c588b5184a2d3d4fee"},{"access_level":"closed","content_type":"text/plain","file_size":124,"creator":"sriegler","checksum":"ce1f163551c96cee45943a8ea29720b6","file_name":"ReadMe.txt","date_created":"2026-02-27T09:13:11Z","relation":"main_file","date_updated":"2026-02-27T09:13:11Z","embargo_to":"open_access","embargo":"2027-02-27","file_id":"21365"}],"doi":"10.15479/AT-ISTA-21363","tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png"},"citation":{"chicago":"Riegler, Stefan. “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21363.","short":"S. Riegler, (2026).","ieee":"S. Riegler, “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species.” Institute of Science and Technology Austria, 2026.","mla":"Riegler, Stefan. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21363.","ista":"Riegler S. 2026. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21363.","apa":"Riegler, S. (2026). Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21363","ama":"Riegler S. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species. 2026. doi:10.15479/AT-ISTA-21363"},"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"abstract":[{"text":"The data contains information on coffee differential gene expression as well as co-expression and trait correlations in two separate experiments. First, contrasting nitrogen supply, second, intra- and interspecific grafting.","lang":"eng"}],"date_created":"2026-02-27T09:18:41Z","has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","_id":"21363","month":"02","oa_version":"Published Version","ddc":["575"],"corr_author":"1","status":"public"},{"date_published":"2026-02-17T00:00:00Z","article_number":"5c08400","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","year":"2026","publication_status":"published","ec_funded":1,"type":"journal_article","month":"02","ddc":["550"],"publication":"Environmental Science & Technology","status":"public","das_tickbox":"1","issue":"6","intvolume":" 60","OA_type":"closed access","language":[{"iso":"eng"}],"publisher":"American Chemical Society","supplementarymaterial":"yes","pmid":1,"abstract":[{"lang":"eng","text":"Global emission inventories often fail to capture the complexities of vehicular pollution in regions with unique fuel mixes, such as Brazil’s extensive biofuel use, leading to significant uncertainties in atmospheric modeling. This study presents a century-long (1960–2100) bottom-up vehicular emission inventory for Brazil, leveraging locally derived emission factors. Our estimates reveal substantial discrepancies in magnitude, timing, and speciation of non-CO2 pollutants (CO, NMHC, PM2.5) compared to leading global inventories (EDGAR, CEDS, CAMS), highlighting critical inaccuracies in widely used data sets. More critically, future projections under Shared Socioeconomic Pathways (SSPs) uncover a novel positive feedback mechanism: rising temperatures significantly enhance vehicular evaporative nonmethane hydrocarbon (NMHC) emissions. This temperature-dependent increase and subsequent NMHC oxidation to CO2 suggest an overlooked pathway that could amplify climate warming and air pollution globally, particularly after a breakpoint around 2050 (p < 0.05). While historical emissions peaked in the 1990s–2000s, nonexhaust PM becomes increasingly important. Air quality simulations using our inventory in the MUSICA model show good regional PM2.5 agreement but highlight challenges in resolving local primary pollutant peaks. This comprehensive inventory provides crucial data for Brazil and uncovers globally relevant climate–chemistry interactions, urging a re-evaluation of regional specificities in global emission assessments."}],"has_accepted_license":"1","date_created":"2026-02-09T06:54:10Z","date_updated":"2026-07-28T07:03:54Z","title":"A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality","researchdata_availability":"yes","dataavailabilitystatement":"Scripts available here https://github.com/ibarraespinosa/musica_vein and here https://github.com/atmoschem/vein.","author":[{"first_name":"Sergio","last_name":"Ibarra-Espinosa","full_name":"Ibarra-Espinosa, Sergio"},{"full_name":"Dias de Freitas, Edmilson","last_name":"Dias de Freitas","first_name":"Edmilson"},{"last_name":"Gaubert","first_name":"Benjamin","full_name":"Gaubert, Benjamin"},{"full_name":"Lichtig, Pablo","first_name":"Pablo","last_name":"Lichtig"},{"last_name":"Ropkins","first_name":"Karl","full_name":"Ropkins, Karl"},{"full_name":"da Silva, Iara","last_name":"da Silva","first_name":"Iara"},{"first_name":"Guilherme","last_name":"Martins Pereira","full_name":"Martins Pereira, Guilherme"},{"last_name":"Schuch","first_name":"Daniel","full_name":"Schuch, Daniel"},{"last_name":"Nascimento","first_name":"Janaina","full_name":"Nascimento, Janaina"},{"first_name":"Leonardo","last_name":"Hoinaski","full_name":"Hoinaski, Leonardo"},{"full_name":"Martins, Leila Droprinchinski","first_name":"Leila Droprinchinski","last_name":"Martins"},{"full_name":"Gavidia-Calderón, Mario","first_name":"Mario","last_name":"Gavidia-Calderón"},{"last_name":"Vara-Vela","first_name":"Angel","full_name":"Vara-Vela, Angel"},{"last_name":"Toledo de Almeida Albuquerque","first_name":"Taciana","full_name":"Toledo de Almeida Albuquerque, Taciana"},{"last_name":"Ynoue","first_name":"Rita Yuri","full_name":"Ynoue, Rita Yuri"},{"first_name":"Sebastian","last_name":"Diez","full_name":"Diez, Sebastian"},{"full_name":"Mera, Zamir","first_name":"Zamir","last_name":"Mera"},{"first_name":"Alejandro","orcid":"0000-0002-1988-5035","last_name":"Casallas Garcia","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","full_name":"Casallas Garcia, Alejandro"},{"last_name":"Vallejo","first_name":"Fidel","full_name":"Vallejo, Fidel"},{"full_name":"Diaz, Valeria","first_name":"Valeria","last_name":"Diaz"},{"last_name":"Pedruzzi","first_name":"Rizzieri","full_name":"Pedruzzi, Rizzieri"},{"full_name":"Abrutzky, Rosana","last_name":"Abrutzky","first_name":"Rosana"},{"last_name":"Franco","first_name":"Marco A.","full_name":"Franco, Marco A."},{"first_name":"Nicolas","last_name":"Huneeus","full_name":"Huneeus, Nicolas"},{"last_name":"Jorquera","first_name":"Hector","full_name":"Jorquera, Hector"},{"full_name":"Belalcázar-Cerón, Luis Carlos","last_name":"Belalcázar-Cerón","first_name":"Luis Carlos"},{"full_name":"Rojas, Néstor Y.","last_name":"Rojas","first_name":"Néstor Y."},{"full_name":"de Fatima Andrade, Maria","first_name":"Maria","last_name":"de Fatima Andrade"},{"first_name":"Louisa","last_name":"Emmons","full_name":"Emmons, Louisa"},{"first_name":"Guy","last_name":"Brasseur","full_name":"Brasseur, Guy"}],"external_id":{"pmid":["41636708"]},"publication_identifier":{"eissn":["1520-5851"],"issn":["0013-936X"]},"acknowledgement":"Part of this material is based upon work supported by the NSF National Center for Atmospheric Research, which is a major facility sponsored by the National Science Foundation under Cooperative Agreement No. 1852977. Casallas was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413. E. D. Freitas thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 313210/2022–5). Silva gratefully acknowledges the financial support from the National Council for Scientific and Technological Development (CNPq), process number 140512/2021–7. P. Lichtig was supported by base funding from the National Commission for Atomic Energy (CNEA, Arg.) and by NSF NCAR. R.Y. Ynoue thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 406728/2022–4). M. A. Franco thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 407752/2023–4). G. M. Pereira thanks the support by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP; Process numbers 2018/07848–9, 2016/18438–0, and 2019/01316–80) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES; Process number 88887.103225/2025–00). M.F. Andrade thanks the support by FAPESP (Process number 2016/18438–0) and CNPQ (Klimapolis INCT).","article_type":"original","day":"17","oa_version":"None","quality_controlled":"1","_id":"21164","doi":"10.1021/acs.est.5c08400","citation":{"short":"S. Ibarra-Espinosa, E. Dias de Freitas, B. Gaubert, P. Lichtig, K. Ropkins, I. da Silva, G. Martins Pereira, D. Schuch, J. Nascimento, L. Hoinaski, L.D. Martins, M. Gavidia-Calderón, A. Vara-Vela, T. Toledo de Almeida Albuquerque, R.Y. Ynoue, S. Diez, Z. Mera, A. Casallas Garcia, F. Vallejo, V. Diaz, R. Pedruzzi, R. Abrutzky, M.A. Franco, N. Huneeus, H. Jorquera, L.C. Belalcázar-Cerón, N.Y. Rojas, M. de Fatima Andrade, L. Emmons, G. Brasseur, Environmental Science &amp; Technology 60 (2026).","chicago":"Ibarra-Espinosa, Sergio, Edmilson Dias de Freitas, Benjamin Gaubert, Pablo Lichtig, Karl Ropkins, Iara da Silva, Guilherme Martins Pereira, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” Environmental Science &amp; Technology. American Chemical Society, 2026. https://doi.org/10.1021/acs.est.5c08400.","apa":"Ibarra-Espinosa, S., Dias de Freitas, E., Gaubert, B., Lichtig, P., Ropkins, K., da Silva, I., … Brasseur, G. (2026). A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &amp; Technology. American Chemical Society. https://doi.org/10.1021/acs.est.5c08400","ama":"Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, et al. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &amp; Technology. 2026;60(6). doi:10.1021/acs.est.5c08400","ista":"Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, Lichtig P, Ropkins K, da Silva I, Martins Pereira G, Schuch D, Nascimento J, Hoinaski L, Martins LD, Gavidia-Calderón M, Vara-Vela A, Toledo de Almeida Albuquerque T, Ynoue RY, Diez S, Mera Z, Casallas Garcia A, Vallejo F, Diaz V, Pedruzzi R, Abrutzky R, Franco MA, Huneeus N, Jorquera H, Belalcázar-Cerón LC, Rojas NY, de Fatima Andrade M, Emmons L, Brasseur G. 2026. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &amp; Technology. 60(6), 5c08400.","ieee":"S. Ibarra-Espinosa et al., “A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality,” Environmental Science &amp; Technology, vol. 60, no. 6. American Chemical Society, 2026.","mla":"Ibarra-Espinosa, Sergio, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” Environmental Science &amp; Technology, vol. 60, no. 6, 5c08400, American Chemical Society, 2026, doi:10.1021/acs.est.5c08400."},"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"volume":60,"department":[{"_id":"CaMu"}],"scopus_import":"1"},{"file":[{"creator":"dernst","file_name":"2026_ReviewsGeophysics_Sauter.pdf","checksum":"9d46167619be91210c45ee9e1f187395","relation":"main_file","date_created":"2026-07-28T06:48:08Z","content_type":"application/pdf","access_level":"open_access","file_size":3012737,"file_id":"22594","success":1,"date_updated":"2026-07-28T06:48:08Z"}],"publication_status":"published","article_processing_charge":"Yes (in subscription journal)","year":"2026","date_published":"2026-03-01T00:00:00Z","article_number":"e2024RG000869","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"type":"journal_article","ec_funded":1,"issue":"1","ddc":["550"],"month":"03","status":"public","publication":"Reviews of Geophysics","das_tickbox":"1","publisher":"Wiley","supplementarymaterial":"no","abstract":[{"lang":"eng","text":"Mountain glaciers are among the natural systems most vulnerable to climate change. However, their interactions with the atmosphere are complex and not fully understood. These interactions can trigger rapid adjustments and climate feedbacks that either amplify or attenuate atmospheric signals, influencing both glacier response and large-scale atmospheric circulation. Observing this functional coupling in nature is challenging because the key processes occur over a wide range of spatial and temporal scales. However, recent advances in observational techniques and modeling have provided new insights into these interactions. In this review, we summarize the current state of knowledge on glacier-atmosphere interactions in high-mountain regions at different scales, and highlight recent advances in observational and numerical modeling. We also highlight important knowledge gaps and outline future research directions to improve the prediction of glacier change in a warming world."}],"date_created":"2026-01-11T23:01:33Z","has_accepted_license":"1","intvolume":" 64","PlanS_conform":"1","language":[{"iso":"eng"}],"OA_type":"hybrid","author":[{"full_name":"Sauter, T.","first_name":"T.","last_name":"Sauter"},{"first_name":"B. W.","last_name":"Brock","full_name":"Brock, B. W."},{"full_name":"Collier, E.","first_name":"E.","last_name":"Collier"},{"full_name":"Goger, B.","last_name":"Goger","first_name":"B."},{"full_name":"Groos, A. R.","last_name":"Groos","first_name":"A. R."},{"full_name":"Haualand, K. F.","first_name":"K. F.","last_name":"Haualand"},{"last_name":"Mott","first_name":"R.","full_name":"Mott, R."},{"first_name":"L.","last_name":"Nicholson","full_name":"Nicholson, L."},{"full_name":"Prinz, R.","last_name":"Prinz","first_name":"R."},{"id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","full_name":"Shaw, Thomas","first_name":"Thomas","orcid":"0000-0001-7640-6152","last_name":"Shaw"},{"full_name":"Stiperski, I.","first_name":"I.","last_name":"Stiperski"},{"full_name":"Georgi, A.","first_name":"A.","last_name":"Georgi"},{"full_name":"Haugeneder, M.","last_name":"Haugeneder","first_name":"M."},{"first_name":"A.","last_name":"Mandal","full_name":"Mandal, A."},{"last_name":"Reynolds","first_name":"D.","full_name":"Reynolds, D."},{"full_name":"Saigger, M.","last_name":"Saigger","first_name":"M."},{"full_name":"Sicart, J. E.","last_name":"Sicart","first_name":"J. E."},{"last_name":"Voordendag","first_name":"A.","full_name":"Voordendag, A."}],"dataavailabilitystatement":"Data were not used, nor created for this research. Software (other than for typesetting) was not used for this research.","researchdata_availability":"no","title":"Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review","date_updated":"2026-07-28T06:49:58Z","day":"01","file_date_updated":"2026-07-28T06:48:08Z","acknowledgement":"This work is the result of collaboration and discussions within HEFEX II, and we are grateful to all colleagues who have contributed to and enriched these discussions in various ways. T. Sauter acknowledges funding from the German Research Foundation (DFG) (Grant 543257843). This research was funded in part by the Austrian Science Fund (FWF) (Grant https://doi.org/10.55776/P36624 and https://doi.org/10.55776/P36306) for which E. Collier and R. Prinz are grateful. A. R. Groos, T. E. Shaw, R. Mott and M. Haugeneder acknowledge Transnational Access from the European Union's H2020 project INTERACT III (Grant 871120) for participation in the HEFEX II campaign and working group. I. Stiperski (Grant Agreement No. 101001691) and A. R. Groos (Grant Agreement No. 948290) acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program. R. Mott acknowledges funding from the Swiss National Science Foundation (SNSF) (Grant 200021_219918). B. Goger is supported by EXCLAIM, a project funded by ETH Zurich. J.E. Sicart acknowledges LabEx OSUG@2020 (Investissements d'avenir - ANR10 LABX56) for participation in the HEFEX II campaign and working group. T. E. Shaw acknowledges funding from the EU Horizon 2020 Marie Skłodowska-Curie Grant 101026058 and 101034413. K. F. Haualand and T. Sauter are supported by the JOSTICE project funded by the Research Council of Norway (RCN Grant 302458).","article_type":"original","publication_identifier":{"eissn":["1944-9208"],"issn":["8755-1209"]},"OA_place":"publisher","oa_version":"Published Version","quality_controlled":"1","_id":"20971","volume":64,"scopus_import":"1","department":[{"_id":"FrPe"}],"doi":"10.1029/2024RG000869","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"mla":"Sauter, T., et al. “Glacier-Atmosphere Interactions and Feedbacks in High-Mountain Regions - A Review.” Reviews of Geophysics, vol. 64, no. 1, e2024RG000869, Wiley, 2026, doi:10.1029/2024RG000869.","ieee":"T. Sauter et al., “Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review,” Reviews of Geophysics, vol. 64, no. 1. Wiley, 2026.","ama":"Sauter T, Brock BW, Collier E, et al. Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review. Reviews of Geophysics. 2026;64(1). doi:10.1029/2024RG000869","apa":"Sauter, T., Brock, B. W., Collier, E., Goger, B., Groos, A. R., Haualand, K. F., … Voordendag, A. (2026). Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review. Reviews of Geophysics. Wiley. https://doi.org/10.1029/2024RG000869","ista":"Sauter T, Brock BW, Collier E, Goger B, Groos AR, Haualand KF, Mott R, Nicholson L, Prinz R, Shaw T, Stiperski I, Georgi A, Haugeneder M, Mandal A, Reynolds D, Saigger M, Sicart JE, Voordendag A. 2026. Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review. Reviews of Geophysics. 64(1), e2024RG000869.","chicago":"Sauter, T., B. W. Brock, E. Collier, B. Goger, A. R. Groos, K. F. Haualand, R. Mott, et al. “Glacier-Atmosphere Interactions and Feedbacks in High-Mountain Regions - A Review.” Reviews of Geophysics. Wiley, 2026. https://doi.org/10.1029/2024RG000869.","short":"T. Sauter, B.W. Brock, E. Collier, B. Goger, A.R. Groos, K.F. Haualand, R. Mott, L. Nicholson, R. Prinz, T. Shaw, I. Stiperski, A. Georgi, M. Haugeneder, A. Mandal, D. Reynolds, M. Saigger, J.E. Sicart, A. Voordendag, Reviews of Geophysics 64 (2026)."},"project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}]},{"doi":"10.1016/j.molcel.2025.11.029","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"chicago":"Kelley, Ron, Sagar Khavnekar, Ricardo D. Righetto, Jessica Heebner, Martin Obr, Xianjun Zhang, Saikat Chakraborty, et al. “Toward Community-Driven Visual Proteomics with Large-Scale Cryo-Electron Tomography of Chlamydomonas Reinhardtii.” Molecular Cell. Elsevier, 2026. https://doi.org/10.1016/j.molcel.2025.11.029.","short":"R. Kelley, S. Khavnekar, R.D. Righetto, J. Heebner, M. Obr, X. Zhang, S. Chakraborty, G. Tagiltsev, A.K. Michael, S. Van Dorst, F. Waltz, C.L. Mccafferty, L. Lamm, S. Zufferey, P. Van Der Stappen, H. Van Den Hoek, W. Wietrzynski, P. Harar, W. Wan, J.A.G. Briggs, J.M. Plitzko, B.D. Engel, A. Kotecha, Molecular Cell 86 (2026) 213–230.e7.","ieee":"R. Kelley et al., “Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii,” Molecular Cell, vol. 86, no. 1. Elsevier, p. 213–230.e7, 2026.","mla":"Kelley, Ron, et al. “Toward Community-Driven Visual Proteomics with Large-Scale Cryo-Electron Tomography of Chlamydomonas Reinhardtii.” Molecular Cell, vol. 86, no. 1, Elsevier, 2026, p. 213–230.e7, doi:10.1016/j.molcel.2025.11.029.","ista":"Kelley R, Khavnekar S, Righetto RD, Heebner J, Obr M, Zhang X, Chakraborty S, Tagiltsev G, Michael AK, Van Dorst S, Waltz F, Mccafferty CL, Lamm L, Zufferey S, Van Der Stappen P, Van Den Hoek H, Wietrzynski W, Harar P, Wan W, Briggs JAG, Plitzko JM, Engel BD, Kotecha A. 2026. Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell. 86(1), 213–230.e7.","apa":"Kelley, R., Khavnekar, S., Righetto, R. D., Heebner, J., Obr, M., Zhang, X., … Kotecha, A. (2026). Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell. Elsevier. https://doi.org/10.1016/j.molcel.2025.11.029","ama":"Kelley R, Khavnekar S, Righetto RD, et al. Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell. 2026;86(1):213-230.e7. doi:10.1016/j.molcel.2025.11.029"},"scopus_import":"1","department":[{"_id":"AlMi"}],"volume":86,"_id":"20935","quality_controlled":"1","oa_version":"Published Version","OA_place":"publisher","day":"08","file_date_updated":"2026-07-28T07:38:45Z","acknowledgement":"Calculations were performed at the Max Planck Institute of Biochemistry and the Raven Supercomputer of the Max Planck Computing and Data Facility (MPCDF) in Garching, Germany; at the sciCORE (http://scicore.unibas.ch/) scientific computing center at the University of Basel, Switzerland; and at Thermo Fisher Scientific, in Eindhoven, the Netherlands. This work was supported by Thermo Fisher Scientific. All lamella preparations and tilt-series collections used in this work were conducted at Thermo Fisher R&D facilities in Brno and Eindhoven, utilizing Arctis and Krios microscopes. This work was also supported by the ERC consolidator grant “cryOcean” (fulfilled by the Swiss State Secretariat for Education, Research and Innovation, M822.00045) as well as a Swiss Nanoscience Institute PhD school grant to B.D.E. and P.V.d.S., an EMBO long-term postdoctoral fellowship (ALTF-383-2022) to G.T., an SNSF Postdoctoral Fellowship (project 210561) to F.W., a Boehringer Ingelheim Fonds fellowship to L.L., and by the Max Planck Society to J.A.G.B. and J.M.P.","publication_identifier":{"eissn":["1097-4164"],"issn":["1097-2765"]},"article_type":"original","researchdata_availability":"yes","title":"Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii","date_updated":"2026-07-28T07:39:23Z","author":[{"last_name":"Kelley","first_name":"Ron","full_name":"Kelley, Ron"},{"first_name":"Sagar","last_name":"Khavnekar","full_name":"Khavnekar, Sagar"},{"first_name":"Ricardo D.","last_name":"Righetto","full_name":"Righetto, Ricardo D."},{"full_name":"Heebner, Jessica","last_name":"Heebner","first_name":"Jessica"},{"orcid":"0000-0003-1756-6564","last_name":"Obr","first_name":"Martin","id":"4741CA5A-F248-11E8-B48F-1D18A9856A87","full_name":"Obr, Martin"},{"full_name":"Zhang, Xianjun","last_name":"Zhang","first_name":"Xianjun"},{"first_name":"Saikat","last_name":"Chakraborty","full_name":"Chakraborty, Saikat"},{"last_name":"Tagiltsev","first_name":"Grigory","full_name":"Tagiltsev, Grigory"},{"id":"6437c950-2a03-11ee-914d-d6476dd7b75c","full_name":"Michael, Alicia","orcid":"0000-0002-6080-839X","last_name":"Michael","first_name":"Alicia"},{"full_name":"Van Dorst, Sofie","last_name":"Van Dorst","first_name":"Sofie"},{"full_name":"Waltz, Florent","first_name":"Florent","last_name":"Waltz"},{"last_name":"Mccafferty","first_name":"Caitlyn L.","full_name":"Mccafferty, Caitlyn L."},{"first_name":"Lorenz","last_name":"Lamm","full_name":"Lamm, Lorenz"},{"last_name":"Zufferey","first_name":"Simon","full_name":"Zufferey, Simon"},{"last_name":"Van Der Stappen","first_name":"Philippe","full_name":"Van Der Stappen, Philippe"},{"first_name":"Hugo","last_name":"Van Den Hoek","full_name":"Van Den Hoek, Hugo"},{"last_name":"Wietrzynski","first_name":"Wojciech","full_name":"Wietrzynski, Wojciech"},{"first_name":"Pavol","orcid":"0000-0001-5206-1794","last_name":"Harar","id":"e03d953a-6e8c-11ef-99e4-f0717d385cd5","full_name":"Harar, Pavol"},{"full_name":"Wan, William","first_name":"William","last_name":"Wan"},{"full_name":"Briggs, John A.G.","first_name":"John A.G.","last_name":"Briggs"},{"last_name":"Plitzko","first_name":"Jürgen M.","full_name":"Plitzko, Jürgen M."},{"last_name":"Engel","first_name":"Benjamin D.","full_name":"Engel, Benjamin D."},{"first_name":"Abhay","last_name":"Kotecha","full_name":"Kotecha, Abhay"}],"dataavailabilitystatement":"Raw EM data are available at the EMPIAR under accession code EMPIAR: EMPIAR-11830. Annotation and processing information for all 1,829 tomograms are provided in spreadsheet format.153 The following subtomogram averages have been deposited at the Electron Microscopy Data Bank (EMDB): 80S ribosome (EMDB: EMD-51847), nucleosome (EMDB: EMD-19906), PSII (EMDB: EMD-51731), Rubisco (EMDB: EMD-51848), microtubule (EMDB: EMD-51804), clathrin (EMDB: EMD-51789), and ATP synthase (EMDB: EMD-51802). Segmentations shown in Figures 2 and 3 are deposited on Zenodo (https://doi.org/10.5281/zenodo.15875785). Particle positions and orientations used for STA, along with all resources derived from this work, are available on GitHub (https://github.com/Chromatin-Structure-Rhythms-Lab/ChlamyAnnotations). Reconstructed tomograms and annotations are also available to explore interactively at the CZII Cryo-ET Data Portal (DS-10302, https://cryoetdataportal.czscience.com/datasets/10302/). Raw data for cryo-PFIB/SEM slice-and-view of a whole C. reinhardtii cell has also been deposited (EMPIAR: EMPIAR-11275).\r\n\r\nThis paper does not report original code.\r\n\r\nAny additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.","OA_type":"hybrid","language":[{"iso":"eng"}],"intvolume":" 86","PlanS_conform":"1","has_accepted_license":"1","date_created":"2026-01-04T23:01:36Z","abstract":[{"text":"In situ cryo-electron tomography (cryo-ET) has emerged as the method of choice to investigate the structures of biomolecules in their native context. However, challenges remain for the efficient production and sharing of large-scale cryo-ET datasets. Here, we combined cryogenic plasma-based focused ion beam (cryo-PFIB) milling with recent advances in cryo-ET acquisition and processing to generate a dataset of 1,829 annotated tomograms of the green alga Chlamydomonas reinhardtii, which we provide as a community resource to drive method development and inspire biological discovery. To assay data quality, we performed subtomogram averaging of both soluble and membrane-bound complexes ranging in size from >3 MDa to ∼200 kDa, including 80S ribosomes, Rubisco, nucleosomes, microtubules, clathrin, photosystem II, and mitochondrial ATP synthase. The majority of these density maps reached sub-nanometer resolution, demonstrating the potential of this C. reinhardtii dataset as well as the promise of modern cryo-ET workflows and open data sharing to empower visual proteomics.","lang":"eng"}],"supplementarymaterial":"yes","publisher":"Elsevier","das_tickbox":"1","publication":"Molecular Cell","status":"public","ddc":["570"],"month":"01","issue":"1","type":"journal_article","oa":1,"page":"213-230.e7","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-01-08T00:00:00Z","publication_status":"published","article_processing_charge":"Yes (in subscription journal)","year":"2026","file":[{"date_updated":"2026-07-28T07:38:45Z","file_id":"22599","success":1,"access_level":"open_access","content_type":"application/pdf","file_size":26749637,"checksum":"96a2f8519124d1a0d9de8d2594bf7147","file_name":"2026_MolecularCell_Kelley.pdf","creator":"dernst","date_created":"2026-07-28T07:38:45Z","relation":"main_file"}]},{"author":[{"first_name":"Ramona","last_name":"Rica","full_name":"Rica, Ramona"},{"first_name":"Klara","last_name":"Klein","full_name":"Klein, Klara"},{"full_name":"Johnson, Litty","last_name":"Johnson","first_name":"Litty"},{"last_name":"Carta","first_name":"Gabriele","full_name":"Carta, Gabriele"},{"full_name":"Sarcevic, Mirza","last_name":"Sarcevic","first_name":"Mirza"},{"first_name":"Freyja","last_name":"Langer","id":"3C1BE782-F248-11E8-B48F-1D18A9856A87","full_name":"Langer, Freyja"},{"full_name":"Rademacher, Christoph","first_name":"Christoph","last_name":"Rademacher"},{"full_name":"Wawrzinek, Robert","first_name":"Robert","last_name":"Wawrzinek"},{"last_name":"Quattrone","first_name":"Federica","full_name":"Quattrone, Federica"},{"full_name":"Sparber, Florian","first_name":"Florian","last_name":"Sparber"}],"dataavailabilitystatement":"The data that support the findings of this study are available on request from the corresponding authors.","title":"Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response","researchdata_availability":"upon request","date_updated":"2026-07-28T07:37:08Z","day":"07","publication_identifier":{"eissn":["1525-0024"],"issn":["1525-0016"]},"acknowledgement":"This project was generously supported by Seedfinancing (grant no. P2282679) of the Austrian Bundesministerium für Digitalisierung und Wirtschaftsstandort and the Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation, und Technologie, handled by the Austrian Wirtschaftsservice (aws), as well as by Life Science Call 2022 (grant no. FO999896442) of the Austrian Research Promotion Agency (FFG). We thank Mag. Michael Schunn from the PCF of the Institute of Science and Technology Austria for his continuous technical support.","article_type":"original","OA_place":"repository","external_id":{"biorxivid":["10.1101/2025.05.05.652195"]},"biorxivid":1,"_id":"20858","oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.05.05.652195"}],"department":[{"_id":"PreCl"}],"scopus_import":"1","volume":34,"citation":{"mla":"Rica, Ramona, et al. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” Molecular Therapy, vol. 34, no. 1, Elsevier, 2026, pp. 397–406, doi:10.1016/j.ymthe.2025.10.008.","ieee":"R. Rica et al., “Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response,” Molecular Therapy, vol. 34, no. 1. Elsevier, pp. 397–406, 2026.","ista":"Rica R, Klein K, Johnson L, Carta G, Sarcevic M, Langer F, Rademacher C, Wawrzinek R, Quattrone F, Sparber F. 2026. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy. 34(1), 397–406.","apa":"Rica, R., Klein, K., Johnson, L., Carta, G., Sarcevic, M., Langer, F., … Sparber, F. (2026). Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy. Elsevier. https://doi.org/10.1016/j.ymthe.2025.10.008","ama":"Rica R, Klein K, Johnson L, et al. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy. 2026;34(1):397-406. doi:10.1016/j.ymthe.2025.10.008","chicago":"Rica, Ramona, Klara Klein, Litty Johnson, Gabriele Carta, Mirza Sarcevic, Freyja Langer, Christoph Rademacher, Robert Wawrzinek, Federica Quattrone, and Florian Sparber. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” Molecular Therapy. Elsevier, 2026. https://doi.org/10.1016/j.ymthe.2025.10.008.","short":"R. Rica, K. Klein, L. Johnson, G. Carta, M. Sarcevic, F. Langer, C. Rademacher, R. Wawrzinek, F. Quattrone, F. Sparber, Molecular Therapy 34 (2026) 397–406."},"doi":"10.1016/j.ymthe.2025.10.008","publication_status":"published","article_processing_charge":"No","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-01-07T00:00:00Z","page":"397-406","type":"journal_article","oa":1,"issue":"1","publication":"Molecular Therapy","status":"public","month":"01","date_created":"2025-12-28T23:01:26Z","abstract":[{"text":"Targeted antigen delivery to immune cells, particularly dendritic cells, has emerged as a promising strategy to enhance therapeutic efficacy of vaccines, while minimizing adverse effects associated with conventional immunization. In this study, we use our previously described small glycomimetic molecule that is selectively recognized by the Langerhans cell (LC)-specific surface receptor Langerin and demonstrate specific delivery of protein antigens to these specialized dendritic cells. Our results show that Langerin-mediated antigen delivery significantly enhances the immune response in vivo, resulting in increased expansion and activation of antigen-specific T cells, compared to immunization with unmodified antigen. We demonstrate the feasibility of our LC-targeted platform for immune cell-specific immunization with protein antigen and underscore the potential of LCs as an access point for next-generation vaccines and immunotherapies.","lang":"eng"}],"supplementarymaterial":"yes","publisher":"Elsevier","language":[{"iso":"eng"}],"OA_type":"green","intvolume":" 34"},{"oa_version":"None","quality_controlled":"1","_id":"20537","citation":{"mla":"Pieber, Bartholomäus. “Photochemical Cross-Couplings Using Semiconducting Materials.” Synlett, vol. 37, no. 1, Georg Thieme Verlag, 2026, pp. 43–54, doi:10.1055/a-2690-9269.","ieee":"B. Pieber, “Photochemical cross-couplings using semiconducting materials,” Synlett, vol. 37, no. 1. Georg Thieme Verlag, pp. 43–54, 2026.","ista":"Pieber B. 2026. Photochemical cross-couplings using semiconducting materials. Synlett. 37(1), 43–54.","ama":"Pieber B. Photochemical cross-couplings using semiconducting materials. Synlett. 2026;37(1):43-54. doi:10.1055/a-2690-9269","apa":"Pieber, B. (2026). Photochemical cross-couplings using semiconducting materials. Synlett. Georg Thieme Verlag. https://doi.org/10.1055/a-2690-9269","chicago":"Pieber, Bartholomäus. “Photochemical Cross-Couplings Using Semiconducting Materials.” Synlett. Georg Thieme Verlag, 2026. https://doi.org/10.1055/a-2690-9269.","short":"B. 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This includes catalytic systems using carbon nitride materials, dye-sensitized TiO₂, covalent organic frameworks (COFs), and conjugated polymers. The rationale behind the selection of materials and how their use led to the identification of catalyst deactivation, structure–activity relationships, and future opportunities is discussed.","lang":"eng"}],"date_published":"2026-01-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","article_processing_charge":"No","publication_status":"published","type":"journal_article","isi":1,"page":"43-54"},{"date_published":"2026-07-11T00:00:00Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","file":[{"relation":"main_file","date_created":"2026-07-13T14:52:19Z","creator":"adepope","checksum":"9ab386790515628d957a194f30a7ccb4","file_name":"2026_Depope_Al_Thesis.pdf","file_size":25109878,"content_type":"application/pdf","access_level":"open_access","file_id":"22316","date_updated":"2026-07-13T14:52:19Z"},{"file_id":"22317","date_updated":"2026-07-13T14:56:41Z","file_name":"2026_Depope_Al_Thesis.zip","creator":"adepope","checksum":"8ed8fb63f76a695d5b6fec35343f4b90","relation":"source_file","date_created":"2026-07-13T14:56:41Z","content_type":"application/zip","access_level":"closed","file_size":1203199939}],"year":"2026","article_processing_charge":"No","keyword":["Approximate Message Passing","GWAS","Genomics","Proteomics","Survival modeling"],"publication_status":"published","oa":1,"type":"dissertation","page":"169","acknowledged_ssus":[{"_id":"ScienComp"}],"corr_author":"1","status":"public","ddc":["576","610","006"],"month":"07","das_tickbox":"1","degree_awarded":"PhD","supervisor":[{"first_name":"Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"},{"full_name":"Mondelli, Marco","id":"27EB676C-8706-11E9-9510-7717E6697425","last_name":"Mondelli","orcid":"0000-0002-3242-7020","first_name":"Marco"}],"language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","alternative_title":["ISTA Thesis"],"has_accepted_license":"1","date_created":"2026-07-10T13:27:20Z","abstract":[{"lang":"eng","text":"Uncovering the genetic architecture of complex traits and pinpointing causal molecular drivers require the ability to distinguish true signals from noise within massive, high-dimensional omics datasets. To extract meaningful biological insights from these datasets, such as identifying causal genetic variants and proteins, scalable and accurate inference methods are essential. To this end, this thesis develops novel Bayesian inference frameworks based on Vector Approximate Message Passing and demonstrates their effectiveness in the modeling of disease onset times and quantitative physical and clinical measures.\r\n\r\nFirst, we introduce gVAMP, a Bayesian framework tailored for Genome-Wide Association Studies that enables the joint modeling of quantitative complex traits across millions of genetic variants. gVAMP demonstrates superior accuracy in variable selection and out-of-sample polygenic risk prediction compared to state-of-the-art approaches. We model human height using 17 million whole-genome sequence variants from the UK Biobank, incorporating a vast number of rare variants and revealing novel associations. gVAMP achieves a prediction accuracy of approximately 46% for human height, representing the highest reported performance for this trait to date. \r\n\r\nSecond, we present vampW, a Bayesian framework for survival analysis applied to proteomic data. By effectively handling right-censoring and complex protein dependencies within the UK Biobank Pharma Proteomics Project dataset, vampW identifies 219 protein associations across 24 disease outcomes, the majority of which are not among the top marginal discoveries. We further adjust protein levels for exponential age effects, yielding 1,308 associations and highlighting the sensitivity of the analysis to the chosen age-correction methodology. Finally, vampW improves upon the variable selection capabilities of the commonly used (penalized) variants of the Cox proportional hazards model and delivers state-of-the-art out-of-sample prediction of disease onset times.\r\n\r\nCollectively, these methods provide powerful tools for dissecting the genetic architecture of complex traits and the proteomic drivers of disease onset. Furthermore, by delivering accurate polygenic risk scores and precise predictions of onset times, this work advances the capabilities of personalized medicine and clinical risk stratification."}],"date_updated":"2026-07-28T07:08:15Z","title":"From sparse selection to risk prediction: Approximate message passing for proteomic survival models and large-scale genomics","author":[{"full_name":"Depope, Al","id":"0b77531d-dbcd-11ea-9d1d-a8eee0bf3830","first_name":"Al","last_name":"Depope"}],"OA_place":"publisher","file_date_updated":"2026-07-13T14:56:41Z","acknowledgement":"This work was supported in part by the Swiss National Science Foundation through the\r\nEccellenza Grant \"Improving estimation and prediction of common complex disease risk\"\r\n(grant number PCEGP3_181181); the European Research Council through the grant\r\n\"Inference in High Dimensions: Light-speed Algorithms and Information Limits\" (grant\r\nnumber 101161364); and the Fondation Jean-Jacques et Felicia Lopez-Loreta through the\r\nPrix Lopez-Loretta 2019.\r\n","related_material":{"record":[{"id":"21488","relation":"part_of_dissertation","status":"public"}]},"publication_identifier":{"issn":["2663-337X"]},"day":"11","doi_confirm":"1","oa_version":"Published Version","_id":"22258","doi":"10.15479/AT-ISTA-22258","citation":{"ama":"Depope A. From sparse selection to risk prediction: Approximate message passing for proteomic survival models and large-scale genomics. 2026. doi:10.15479/AT-ISTA-22258","ista":"Depope A. 2026. From sparse selection to risk prediction: Approximate message passing for proteomic survival models and large-scale genomics. Institute of Science and Technology Austria.","apa":"Depope, A. (2026). From sparse selection to risk prediction: Approximate message passing for proteomic survival models and large-scale genomics. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-22258","mla":"Depope, Al. From Sparse Selection to Risk Prediction: Approximate Message Passing for Proteomic Survival Models and Large-Scale Genomics. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-22258.","ieee":"A. Depope, “From sparse selection to risk prediction: Approximate message passing for proteomic survival models and large-scale genomics,” Institute of Science and Technology Austria, 2026.","short":"A. Depope, From Sparse Selection to Risk Prediction: Approximate Message Passing for Proteomic Survival Models and Large-Scale Genomics, Institute of Science and Technology Austria, 2026.","chicago":"Depope, Al. “From Sparse Selection to Risk Prediction: Approximate Message Passing for Proteomic Survival Models and Large-Scale Genomics.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-22258."},"project":[{"name":"Prix Lopez-Loretta 2019 - Marco Mondelli","_id":"059876FA-7A3F-11EA-A408-12923DDC885E"},{"name":"Inference in High Dimensions: Light-speed Algorithms and Information Limits","grant_number":"101161364","_id":"911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf"},{"grant_number":"PCEGP3_181181","name":"Improving estimation and prediction of common complex disease risk","_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A"}],"department":[{"_id":"GradSch"},{"_id":"MaRo"},{"_id":"MaMo"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-05-13T00:00:00Z","article_number":"101162","publication_status":"published","year":"2026","article_processing_charge":"Yes","file":[{"date_updated":"2026-07-28T07:06:26Z","file_id":"22596","success":1,"file_size":3736705,"content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2026-07-28T07:06:26Z","file_name":"2026_CellGenomics_Depope.pdf","checksum":"6b59686f8d9733add4f23d23f3dd9df0","creator":"dernst"}],"type":"journal_article","oa":1,"das_tickbox":"1","month":"05","publication":"Cell Genomics","ddc":["000","570"],"status":"public","corr_author":"1","issue":"5","language":[{"iso":"eng"}],"OA_type":"gold","intvolume":" 6","abstract":[{"lang":"eng","text":"Human height is a model for the genetic analysis of complex traits, and recent studies suggest the presence of thousands of common genetic variant associations and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic paradigm based on approximate message passing (genomic vector approximate message passing [gVAMP]) for identifying DNA sequence variants associated with complex traits and common diseases in large-scale whole-genome sequencing (WGS) data. We show that gVAMP accurately localizes associations to variants with the correct frequency and position in the DNA, outperforming existing fine-mapping methods in selecting the appropriate genetic variants within WGS data. We then apply gVAMP to jointly model the relationship of tens of millions of WGS variants with human height in hundreds of thousands of UK Biobank individuals. We identify 59 rare variants and gene burden scores alongside many hundreds of DNA regions containing common variant associations and show that understanding the genetic basis of complex traits will require the joint analysis of hundreds of millions of variables measured on millions of people. The polygenic risk scores obtained from gVAMP have high accuracy (including a prediction accuracy of ∼46% for human height) and outperform current methods for downstream tasks such as mixed linear model association testing across 13 UK Biobank traits. In conclusion, gVAMP offers a scalable foundation for a wider range of analyses in WGS data."}],"pmid":1,"date_created":"2026-03-23T15:10:03Z","has_accepted_license":"1","publisher":"Elsevier","supplementarymaterial":"yes","title":"Joint modeling of whole-genome sequencing data for human height via approximate message passing","researchdata_availability":"yes","date_updated":"2026-07-28T07:08:15Z","author":[{"full_name":"Depope, Al","id":"0b77531d-dbcd-11ea-9d1d-a8eee0bf3830","first_name":"Al","last_name":"Depope"},{"full_name":"Bajzik, Jakub","id":"b995e25b-8c4b-11ed-a6d8-f71b7bcd6122","last_name":"Bajzik","first_name":"Jakub"},{"id":"27EB676C-8706-11E9-9510-7717E6697425","full_name":"Mondelli, Marco","first_name":"Marco","orcid":"0000-0002-3242-7020","last_name":"Mondelli"},{"last_name":"Robinson","orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"}],"dataavailabilitystatement":"This project uses the UK Biobank data under project number 35520. UK Biobank genotypic and phenotypic data are available through a formal request at http://www.ukbiobank.ac.uk. It also uses genotypic and phenotypic data from the All of Us study, which are also available through a formal request at https://www.researchallofus.org/data-tools/data-access/. All summary statistic estimates are released publicly on Dryad: https://doi.org/10.5061/dryad.cz8w9gjjc.\r\n•\r\nThe gVAMP code developed in this work is open source and has been deposited on GitHub, where it is publicly available at https://github.com/medical-genomics-group/gVAMP, and the code used to generate the data in the manuscript are available from Zenodo https://doi.org/10.5281/zenodo.17935521. The URLs of other software used are listed in the key resources table.","OA_place":"publisher","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","external_id":{"pmid":["41713425"]},"day":"13","article_type":"original","file_date_updated":"2026-07-28T07:06:26Z","acknowledgement":"We thank Malgorzata Borczyk for creating the gene burden scores. We thank Robin Beaumont, Amedeo Roberto Esposito, Gareth Hawkes, Philip Schniter, Matthew Stephens, Pragya Sur, Peter Visscher, Michael Weedon, and Harry Wright for providing valuable suggestions and comments on earlier versions of the work. This project was funded by a Lopez-Loreta Prize to M.M., an SNSF Eccellenza Grant to M.R.R. (PCEGP3-181181), an ERC Starting Grant to M.M. (INF2, project number 101161364), and core funding from ISTA. High-performance computing was supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp). We would like to acknowledge the participants and investigators of the UK Biobank study. We gratefully acknowledge the All of Us participants for their contributions, without whom this research would not have been possible. We also thank the National Institutes of Health All of Us Research Program for making available the participant data (and/or samples and/or cohort) examined in this study.","related_material":{"record":[{"id":"22258","relation":"dissertation_contains","status":"public"}],"link":[{"url":"https://ista.ac.at/en/news/big-data-and-human-height/","relation":"press_release","description":"News on ISTA website"}]},"publication_identifier":{"eissn":["2666-979X"]},"DOAJ_listed":"1","_id":"21488","quality_controlled":"1","oa_version":"Published Version","project":[{"name":"Prix Lopez-Loretta 2019 - Marco Mondelli","_id":"059876FA-7A3F-11EA-A408-12923DDC885E"},{"name":"Inference in High Dimensions: Light-speed Algorithms and Information Limits","grant_number":"101161364","_id":"911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf"},{"_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A","name":"Improving estimation and prediction of common complex disease risk","grant_number":"PCEGP3_181181"}],"citation":{"ista":"Depope A, Bajzik J, Mondelli M, Robinson MR. 2026. Joint modeling of whole-genome sequencing data for human height via approximate message passing. Cell Genomics. 6(5), 101162.","apa":"Depope, A., Bajzik, J., Mondelli, M., & Robinson, M. R. (2026). Joint modeling of whole-genome sequencing data for human height via approximate message passing. Cell Genomics. Elsevier. https://doi.org/10.1016/j.xgen.2026.101162","ama":"Depope A, Bajzik J, Mondelli M, Robinson MR. Joint modeling of whole-genome sequencing data for human height via approximate message passing. Cell Genomics. 2026;6(5). doi:10.1016/j.xgen.2026.101162","mla":"Depope, Al, et al. “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate Message Passing.” Cell Genomics, vol. 6, no. 5, 101162, Elsevier, 2026, doi:10.1016/j.xgen.2026.101162.","ieee":"A. Depope, J. Bajzik, M. Mondelli, and M. R. Robinson, “Joint modeling of whole-genome sequencing data for human height via approximate message passing,” Cell Genomics, vol. 6, no. 5. Elsevier, 2026.","short":"A. Depope, J. Bajzik, M. Mondelli, M.R. Robinson, Cell Genomics 6 (2026).","chicago":"Depope, Al, Jakub Bajzik, Marco Mondelli, and Matthew Richard Robinson. “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate Message Passing.” Cell Genomics. Elsevier, 2026. https://doi.org/10.1016/j.xgen.2026.101162."},"tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"doi":"10.1016/j.xgen.2026.101162","scopus_import":"1","department":[{"_id":"MaMo"},{"_id":"MaRo"}],"volume":6},{"quality_controlled":"1","oa_version":"Published Version","_id":"22267","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.1016/j.cub.2026.06.016","citation":{"chicago":"Ewe, Chee Kiang, Hanna Achache, Hanna Schön, Leonid Kontorovich, Guy Teichman, Shir Weiss, Anna Mogilevskaya, et al. “Neuronal RNAi and Oxygen-Sensing Circuit Shape Germline Resilience to Heat Stress.” Current Biology. Elsevier, 2026. https://doi.org/10.1016/j.cub.2026.06.016.","short":"C.K. Ewe, H. Achache, H. Schön, L. Kontorovich, G. Teichman, S. Weiss, A. Mogilevskaya, M. Valenski, S. Anava, R. Bardapurkar, H. Gingold, R. Posner, O. Antonova, M. de Bono, Y.B. Tzur, O. Rechavi, Current Biology 36 (2026) 3566–3579.e5.","mla":"Ewe, Chee Kiang, et al. “Neuronal RNAi and Oxygen-Sensing Circuit Shape Germline Resilience to Heat Stress.” Current Biology, vol. 36, no. 14, Elsevier, 2026, p. 3566–3579.e5, doi:10.1016/j.cub.2026.06.016.","ieee":"C. K. Ewe et al., “Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress,” Current Biology, vol. 36, no. 14. Elsevier, p. 3566–3579.e5, 2026.","ama":"Ewe CK, Achache H, Schön H, et al. Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress. Current Biology. 2026;36(14):3566-3579.e5. doi:10.1016/j.cub.2026.06.016","apa":"Ewe, C. K., Achache, H., Schön, H., Kontorovich, L., Teichman, G., Weiss, S., … Rechavi, O. (2026). Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2026.06.016","ista":"Ewe CK, Achache H, Schön H, Kontorovich L, Teichman G, Weiss S, Mogilevskaya A, Valenski M, Anava S, Bardapurkar R, Gingold H, Posner R, Antonova O, de Bono M, Tzur YB, Rechavi O. 2026. Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress. Current Biology. 36(14), 3566–3579.e5."},"volume":36,"scopus_import":"1","department":[{"_id":"MaDe"}],"date_updated":"2026-07-28T07:32:06Z","title":"Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress","researchdata_availability":"upon request","dataavailabilitystatement":"* All NGS data are available through GEO under accession number GSE331410.\r\n* This paper does not report original code.\r\n* Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.","author":[{"full_name":"Ewe, Chee Kiang","first_name":"Chee Kiang","last_name":"Ewe"},{"first_name":"Hanna","last_name":"Achache","full_name":"Achache, Hanna"},{"full_name":"Schön, Hanna","id":"C8E17EDC-D7AA-11E9-B7B7-45ECE5697425","last_name":"Schön","first_name":"Hanna"},{"first_name":"Leonid","last_name":"Kontorovich","full_name":"Kontorovich, Leonid"},{"last_name":"Teichman","first_name":"Guy","full_name":"Teichman, Guy"},{"first_name":"Shir","last_name":"Weiss","full_name":"Weiss, Shir"},{"full_name":"Mogilevskaya, Anna","first_name":"Anna","last_name":"Mogilevskaya"},{"full_name":"Valenski, Myriam","first_name":"Myriam","last_name":"Valenski"},{"first_name":"Sarit","last_name":"Anava","full_name":"Anava, Sarit"},{"full_name":"Bardapurkar, Rutwik","first_name":"Rutwik","last_name":"Bardapurkar"},{"full_name":"Gingold, Hila","last_name":"Gingold","first_name":"Hila"},{"first_name":"Rachel","last_name":"Posner","full_name":"Posner, Rachel"},{"last_name":"Antonova","first_name":"Olga","full_name":"Antonova, Olga"},{"full_name":"De Bono, Mario","id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","last_name":"De Bono","orcid":"0000-0001-8347-0443","first_name":"Mario"},{"full_name":"Tzur, Yonatan B.","first_name":"Yonatan B.","last_name":"Tzur"},{"first_name":"Oded","last_name":"Rechavi","full_name":"Rechavi, Oded"}],"external_id":{"pmid":["42409014"]},"OA_place":"publisher","file_date_updated":"2026-07-28T07:31:44Z","publication_identifier":{"issn":["0960-9822"],"eissn":["1879-0445"]},"acknowledgement":"We thank Itai Reiger for their assistance with experiments. We thank Cori Bargmann (Rockefeller University) for providing introgressed strains carrying HW alleles of npr-1 and glb-5. Some graphics were created with Biorender.com. We are grateful to WormBase for providing valuable data and resources. Some strains were provided by the Caenorhabditis Genetics Center (CGC), which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440). O.R. is grateful for the support of the Morris Kahn Foundation. C.K.E. was supported by an EMBO fellowship ALTF 6-2022. This work is funded by Eric and Wendy Schmidt Fund for Strategic Innovation Polymath Award 0140001000 (O.R.); European Research Council grant 335624 (O.R.); Israel Science Foundation 979/21 (Y.B.T.); and the US-Israel Binational Science Foundation 2023036 (Y.B.T.).","article_type":"original","day":"20","status":"public","publication":"Current Biology","month":"07","ddc":["570"],"das_tickbox":"1","issue":"14","intvolume":" 36","language":[{"iso":"eng"}],"OA_type":"hybrid","supplementarymaterial":"yes","publisher":"Elsevier","has_accepted_license":"1","date_created":"2026-07-12T22:02:18Z","pmid":1,"abstract":[{"text":"Thermal pollution, whether local or driven by global warming, threatens biodiversity in part through its detrimental effects on reproduction. Non-coding small RNAs (sRNAs) are crucial for maintaining germline developmental robustness under heat stress. Remarkably, we uncovered that neuronal sRNAs regulate germ cells’ thermotolerance, affecting both spermatogenic and oogenic germlines in a cell-non-autonomous manner. Furthermore, we demonstrate that, in RNAi mutants, an oxygen-sensing neural circuit, modulated by neuropeptide signaling, antagonizes germline maintenance, likely reflecting the nematode’s innate association of reduced oxygen levels with food availability and reproductive permissive environments. Finally, we provide evidence that laboratory-domesticated alleles of oxygen-response genes encoding neuropeptide receptor NPR-1 and hexacoordinated globin GLB-5 compromise germline thermotolerance. Hence, our findings raise the possibility that sensory perception, independent of direct environmental change, modulates germline integrity, highlighting a novel mechanism by which neural circuits integrate environmental information to safeguard reproductive fitness in fluctuating environments.","lang":"eng"}],"date_published":"2026-07-20T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_size":6795092,"content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2026-07-28T07:31:44Z","file_name":"2026_CurrentBiology_KiangEwe.pdf","creator":"dernst","checksum":"5ec4472d81fd44de03ccb92b1eb690a6","date_updated":"2026-07-28T07:31:44Z","file_id":"22598","success":1}],"article_processing_charge":"Yes (in subscription journal)","year":"2026","publication_status":"published","oa":1,"type":"journal_article","page":"3566-3579.e5"},{"oa":1,"type":"journal_article","page":"7429–7434","date_published":"2026-06-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_name":"2026_NanoLetters_Gulyaev.pdf","checksum":"897551374cac28e0db26dcb0b676b8e7","creator":"dernst","date_created":"2026-06-16T09:11:35Z","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_size":3362800,"success":1,"file_id":"22013","date_updated":"2026-06-16T09:11:35Z"}],"publication_status":"published","article_processing_charge":"Yes (via OA deal)","year":"2026","intvolume":" 26","PlanS_conform":"1","OA_type":"hybrid","language":[{"iso":"eng"}],"publisher":"American Chemical Society","pmid":1,"abstract":[{"lang":"eng","text":"Despite significant progress in the field of molecular electronics over the last two decades, the quantitative prediction of metal-molecule-metal junction conductance remains a challenge. The standard computational framework combines density functional theory (DFT) with nonequilibrium Green’s functions (NEGF) using low-rung exchange-correlation functionals such as PBE, which overestimate the conductances. More advanced correction methods exist but require complex workflows and high computational cost, limiting their accessibility. Here, we introduce a physically motivated approach that approximates results obtained with high-rung functionals. Our method fits the PBE-calculated transmission to a Breit-Wigner form and subsequently refines the fit parameters using molecular orbital energies and metal densities of states computed for the isolated subsystems with high-rung functionals. This approach is applicable to a broad range of molecular junctions yielding conductance values in quantitative agreement with experiments. Our approach is simple, low-cost, and accurate, making it well-suited for routine and large-scale prediction of single-molecule junction conductance."}],"has_accepted_license":"1","date_created":"2026-06-10T07:27:19Z","status":"public","ddc":["540"],"month":"06","corr_author":"1","publication":"Nano Letters","das_tickbox":"1","issue":"22","external_id":{"chemrxivid":["10.26434/chemrxiv.15001696"],"pmid":["42223342"]},"OA_place":"publisher","day":"01","acknowledgement":"This work was supported primarily by the Institute of Science and Technology Austria. L.V. was supported in part by the National Science Foundation (No. NSF-DMR 2241180). Z.-F.L. was supported by an NSF CAREER Award, No. DMR-2044552 and an Alfred P. Sloan Research Fellowship, No. FG-2024-21750.","article_type":"letter_note","file_date_updated":"2026-06-16T09:11:35Z","publication_identifier":{"issn":["1530-6984"],"eissn":["1530-6992"]},"title":"A computationally efficient and accurate method for predicting conductance of single-molecule junctions","date_updated":"2026-07-28T09:57:28Z","chemrxivid":1,"author":[{"first_name":"Artem","last_name":"Gulyaev","id":"83ed7901-7380-11f0-bf20-a0788d5e654d","full_name":"Gulyaev, Artem"},{"last_name":"Hazarika","orcid":"0009-0007-2542-7878","first_name":"Jyotisman","full_name":"Hazarika, Jyotisman","id":"d87714c4-663d-11f0-bd06-caece19833e5"},{"last_name":"Liu","first_name":"Zhen-Fei","full_name":"Liu, Zhen-Fei"},{"first_name":"Latha","last_name":"Venkataraman","orcid":"0000-0002-6957-6089","full_name":"Venkataraman, Latha","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf"}],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.1021/acs.nanolett.6c01462","citation":{"chicago":"Gulyaev, Artem, Jyotisman Hazarika, Zhen-Fei Liu, and Latha Venkataraman. “A Computationally Efficient and Accurate Method for Predicting Conductance of Single-Molecule Junctions.” Nano Letters. American Chemical Society, 2026. https://doi.org/10.1021/acs.nanolett.6c01462.","short":"A. Gulyaev, J. Hazarika, Z.-F. Liu, L. Venkataraman, Nano Letters 26 (2026) 7429–7434.","ieee":"A. Gulyaev, J. Hazarika, Z.-F. Liu, and L. Venkataraman, “A computationally efficient and accurate method for predicting conductance of single-molecule junctions,” Nano Letters, vol. 26, no. 22. American Chemical Society, pp. 7429–7434, 2026.","mla":"Gulyaev, Artem, et al. “A Computationally Efficient and Accurate Method for Predicting Conductance of Single-Molecule Junctions.” Nano Letters, vol. 26, no. 22, American Chemical Society, 2026, pp. 7429–7434, doi:10.1021/acs.nanolett.6c01462.","ista":"Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. 2026. A computationally efficient and accurate method for predicting conductance of single-molecule junctions. Nano Letters. 26(22), 7429–7434.","apa":"Gulyaev, A., Hazarika, J., Liu, Z.-F., & Venkataraman, L. (2026). A computationally efficient and accurate method for predicting conductance of single-molecule junctions. Nano Letters. American Chemical Society. https://doi.org/10.1021/acs.nanolett.6c01462","ama":"Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. A computationally efficient and accurate method for predicting conductance of single-molecule junctions. 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Kleinhanns, Unraveling the Origin and Evolution of Defects to Enable Advanced Thermoelectric Performance, Institute of Science and Technology Austria, 2026.","chicago":"Kleinhanns, Tobias. “Unraveling the Origin and Evolution of Defects to Enable Advanced Thermoelectric Performance.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-22017.","ama":"Kleinhanns T. Unraveling the origin and evolution of defects to enable advanced thermoelectric performance. 2026. doi:10.15479/AT-ISTA-22017","ista":"Kleinhanns T. 2026. Unraveling the origin and evolution of defects to enable advanced thermoelectric performance. Institute of Science and Technology Austria.","apa":"Kleinhanns, T. (2026). Unraveling the origin and evolution of defects to enable advanced thermoelectric performance. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-22017","mla":"Kleinhanns, Tobias. Unraveling the Origin and Evolution of Defects to Enable Advanced Thermoelectric Performance. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-22017.","ieee":"T. Kleinhanns, “Unraveling the origin and evolution of defects to enable advanced thermoelectric performance,” Institute of Science and Technology Austria, 2026."},"project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"department":[{"_id":"GradSch"},{"_id":"MaIb"}]},{"external_id":{"arxiv":["2408.16848"]},"OA_place":"publisher","arxiv":1,"acknowledgement":"We thank G. M. Koutentakis, S. Wimberger, J. G. E. Harris, T. Enss, and A. Ghazaryan for fruitful discussions. M.L. acknowledges support by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). R.-J.S. acknowledges funding from a EPSRC ERC underwrite (Grant No. EP/X025829/1), a EPSRC New Investigator Award (Grant No. EP/W00187X/1), and Trinity College, Cambridge. F.N.Ü. acknowledges support from the Marie Skłodowska-Curie Programme of the European Commission (Grant No. 893915), a Simons Investigator Award (Grant No. 511029), Trinity College Cambridge, and the Royal Society (Grant No. URF/R1/241667).","article_type":"original","related_material":{"record":[{"status":"public","relation":"earlier_version","id":"19425"}]},"file_date_updated":"2026-01-21T09:04:48Z","publication_identifier":{"eissn":["2469-9934"],"issn":["2469-9926"]},"day":"12","date_updated":"2026-07-29T08:59:30Z","title":"Anomalous multigap topological phases in periodically driven quantum rotors","author":[{"full_name":"Karle, Volker","id":"D7C012AE-D7ED-11E9-95E8-1EC5E5697425","last_name":"Karle","orcid":"0000-0002-6963-0129","first_name":"Volker"},{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","first_name":"Mikhail","orcid":"0000-0002-6990-7802","last_name":"Lemeshko"},{"full_name":"Bouhon, Adrien","last_name":"Bouhon","first_name":"Adrien"},{"full_name":"Slager, Robert-Jan","first_name":"Robert-Jan","last_name":"Slager"},{"full_name":"Ünal, F. Nur","last_name":"Ünal","first_name":"F. Nur"}],"citation":{"short":"V. Karle, M. Lemeshko, A. Bouhon, R.-J. Slager, F.N. Ünal, Physical Review A 113 (2026).","chicago":"Karle, Volker, Mikhail Lemeshko, Adrien Bouhon, Robert-Jan Slager, and F. Nur Ünal. “Anomalous Multigap Topological Phases in Periodically Driven Quantum Rotors.” Physical Review A. American Physical Society, 2026. https://doi.org/10.1103/db9d-9bns.","ista":"Karle V, Lemeshko M, Bouhon A, Slager R-J, Ünal FN. 2026. Anomalous multigap topological phases in periodically driven quantum rotors. Physical Review A. 113(1), 012216.","apa":"Karle, V., Lemeshko, M., Bouhon, A., Slager, R.-J., & Ünal, F. N. (2026). Anomalous multigap topological phases in periodically driven quantum rotors. Physical Review A. American Physical Society. https://doi.org/10.1103/db9d-9bns","ama":"Karle V, Lemeshko M, Bouhon A, Slager R-J, Ünal FN. Anomalous multigap topological phases in periodically driven quantum rotors. Physical Review A. 2026;113(1). doi:10.1103/db9d-9bns","mla":"Karle, Volker, et al. “Anomalous Multigap Topological Phases in Periodically Driven Quantum Rotors.” Physical Review A, vol. 113, no. 1, 012216, American Physical Society, 2026, doi:10.1103/db9d-9bns.","ieee":"V. Karle, M. Lemeshko, A. Bouhon, R.-J. Slager, and F. N. Ünal, “Anomalous multigap topological phases in periodically driven quantum rotors,” Physical Review A, vol. 113, no. 1. American Physical Society, 2026."},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.1103/db9d-9bns","project":[{"_id":"2688CF98-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"801770","name":"Angulon: physics and applications of a new quasiparticle"}],"volume":113,"scopus_import":"1","department":[{"_id":"MiLe"}],"quality_controlled":"1","oa_version":"Published Version","_id":"21009","oa":1,"type":"journal_article","ec_funded":1,"article_number":"012216","date_published":"2026-01-12T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"creator":"dernst","file_name":"2026_PhysicalReviewA_Karle.pdf","checksum":"ca62a5050a234c0554e2583b1c126057","relation":"main_file","date_created":"2026-01-21T09:04:48Z","content_type":"application/pdf","access_level":"open_access","file_size":2650256,"success":1,"file_id":"21029","date_updated":"2026-01-21T09:04:48Z"}],"article_processing_charge":"Yes (via OA deal)","year":"2026","publication_status":"published","PlanS_conform":"1","intvolume":" 113","language":[{"iso":"eng"}],"OA_type":"hybrid","publisher":"American Physical Society","abstract":[{"lang":"eng","text":"We demonstrate that periodically driven quantum rotors provide a promising and broadly applicable platform to implement multigap topological phases, where groups of bands can acquire topological invariants due to non-Abelian braiding of band degeneracies. By adiabatically varying the periodic kicks to the rotor we find nodal-line braiding, which causes sign flips of topological charges of band nodes and can prevent them from annihilating, indicated by nonzero values of the patch Euler class. In particular, we report on the emergence of an anomalous Dirac string phase arising in the strongly driven regime, a truly out-of-equilibrium phase of the quantum rotor. This phase emanates from braiding processes involving all (quasienergy) gaps and manifests itself with edge states at zero angular momentum. Our results reveal direct applications in state-of-the-art experiments of quantum rotors, such as linear molecules driven by periodic far-off-resonant laser pulses or artificial quantum rotors in optical lattices, whose extensive versatility offers precise modification and observation of novel non-Abelian topological properties."}],"has_accepted_license":"1","date_created":"2026-01-20T10:06:07Z","month":"01","ddc":["530"],"status":"public","publication":"Physical Review A","corr_author":"1","issue":"1"},{"status":"public","month":"06","publication":"Marine Pollution Bulletin","das_tickbox":"1","issue":"6","intvolume":" 227","OA_type":"closed access","language":[{"iso":"eng"}],"supplementarymaterial":"yes","publisher":"Elsevier","pmid":1,"abstract":[{"lang":"eng","text":"This preliminary study investigates the trace-element composition of ostracod shells (Ostracoda: Crustacea) as biogenic calcium carbonates in their role as environmental sentinels of pollution. Using high-resolution in-situ analysis, we compared two contrasting coastal systems: the highly urbanized seascape of metropolitan megacity Hong Kong (HKSAR) and the agriculturally dominated waters of rural retreat Jeju Island, Republic of Korea (ROK). The goal was to assess whether anthropogenic stress gradients affect trace element-to‑calcium ratios (E/Ca) in the carapaces of shallow-marine Neonesidea Maddocks, 1969 species. Hereby, the focus is laid on potential differences in the effects of extreme urbanization and extreme agriculturalization. We analyzed 12 trace elements commonly incorporated into ostracod shells using Inductively Coupled Plasma–Mass Spectrometry (ICP-MS). Only Mn/Ca, Mg/Ca, and Ni/Ca ratios showed strong correlations with specific seawater physicochemical parameters. Notably, Mn/Ca differed significantly between the two sites, seemingly driven mainly by variations in nitrite nitrogen levels. This suggests that Mn incorporation is sensitive to pollution source, urban versus agricultural, though species-specific uptake effects cannot be excluded. No significant differences in elemental uptake were found between adult and A-1 juvenile stages of Neonesidea mutsuensis Ishizaki, 1961 or Neonesidea elegans (Brady, 1969), supporting the use of both age groups in environmental reconstructions and increasing potential sample yields. While remaining empirical and exploratory, our tentative findings suggest that ostracod geochemistry holds promise for marine pollution monitoring and cautiously supports the application of ostracod Mn/Ca ratios to reconstruct anthropogenic, particularly nitrogen-related, impacts in nearshore environments using sediment core records."}],"date_created":"2026-03-08T23:01:44Z","date_published":"2026-06-01T00:00:00Z","article_number":"119493","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","year":"2026","publication_status":"published","type":"journal_article","quality_controlled":"1","oa_version":"None","_id":"21406","citation":{"short":"A.B. Jöst, M.J. Rodriguez Moreno, T. Kim, D.M. Baker, M. Yasuhara, C.A. Not, I. Karanovic, Marine Pollution Bulletin 227 (2026).","chicago":"Jöst, Anna B., Maximiliano J Rodriguez Moreno, Taihun Kim, David M. Baker, Moriaki Yasuhara, Christelle A. Not, and Ivana Karanovic. “Ostracod Shell Chemistry as Proxy for Coastal Marine Conditions of a Highly Urbanized Megacity (Hong Kong SAR) and an Agro-Centric Oceanic Province (Jeju Island, Republic of Korea) – a Preliminary Comparative Analysis.” Marine Pollution Bulletin. Elsevier, 2026. https://doi.org/10.1016/j.marpolbul.2026.119493.","apa":"Jöst, A. B., Rodriguez Moreno, M. J., Kim, T., Baker, D. M., Yasuhara, M., Not, C. A., & Karanovic, I. (2026). Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis. Marine Pollution Bulletin. Elsevier. https://doi.org/10.1016/j.marpolbul.2026.119493","ista":"Jöst AB, Rodriguez Moreno MJ, Kim T, Baker DM, Yasuhara M, Not CA, Karanovic I. 2026. Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis. Marine Pollution Bulletin. 227(6), 119493.","ama":"Jöst AB, Rodriguez Moreno MJ, Kim T, et al. Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis. Marine Pollution Bulletin. 2026;227(6). doi:10.1016/j.marpolbul.2026.119493","ieee":"A. B. Jöst et al., “Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis,” Marine Pollution Bulletin, vol. 227, no. 6. Elsevier, 2026.","mla":"Jöst, Anna B., et al. “Ostracod Shell Chemistry as Proxy for Coastal Marine Conditions of a Highly Urbanized Megacity (Hong Kong SAR) and an Agro-Centric Oceanic Province (Jeju Island, Republic of Korea) – a Preliminary Comparative Analysis.” Marine Pollution Bulletin, vol. 227, no. 6, 119493, Elsevier, 2026, doi:10.1016/j.marpolbul.2026.119493."},"doi":"10.1016/j.marpolbul.2026.119493","volume":227,"department":[{"_id":"FrPe"}],"scopus_import":"1","date_updated":"2026-07-29T10:09:31Z","title":"Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis","researchdata_availability":"yes","dataavailabilitystatement":"The datasets analysed during the current study are available within the manuscript and the associated supplementary materials.","author":[{"full_name":"Jöst, Anna B.","first_name":"Anna B.","last_name":"Jöst"},{"full_name":"Rodriguez Moreno, Maximiliano J","id":"59bea3b2-8c82-11ef-a41a-af7b0efd9065","first_name":"Maximiliano J","last_name":"Rodriguez Moreno"},{"first_name":"Taihun","last_name":"Kim","full_name":"Kim, Taihun"},{"last_name":"Baker","first_name":"David M.","full_name":"Baker, David M."},{"last_name":"Yasuhara","first_name":"Moriaki","full_name":"Yasuhara, Moriaki"},{"last_name":"Not","first_name":"Christelle A.","full_name":"Not, Christelle A."},{"full_name":"Karanovic, Ivana","last_name":"Karanovic","first_name":"Ivana"}],"external_id":{"pmid":["41774948"]},"article_type":"original","publication_identifier":{"eissn":["1879-3363"],"issn":["002-5326X"]},"acknowledgement":"We thank the KIOST staff of the Jeju Marine Research Center for assisting sample collection, the research assistants and students of the Yoon Idea Lab led by Prof. Dr. Tae-Hyun Yoon at Hanyang University for facilitating and assisting in ICP-MS test runs involved in a pilot study preceding this study, Ms. Garance Perrois and Mr. Léonard Pons for assistance with statistics-related questions, and the two anonymous reviewers for their valuable comments and suggestions. The study described in this article was partially supported by grants from the Brain Pool Program through NRF funded by the Ministry of Science and ICT (reference code: 2019H1D3A1A01070922 to ABJ), by the Ministry of Oceans and Fisheries (grant number RS-2024-00406249 to TK), by the Korea Institute of Marine Science and Technology (KIMST), funded by the Ministry of Oceans and Fisheries (grant number RS-2025-02304432 to TK), and by the Korea Institute of Ocean Science and Technology (PEA0404 to TK).","day":"01"}]