[{"page":"614-642","date_created":"2024-12-23T11:03:59Z","acknowledgement":"L.P. gratefully acknowledges fundings from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – GZ 2047/1, Projekt-ID 390685813. F.Q. gratefully acknowledges support from the Austrian Science Fund (FWF) project 10.55776/F65.","article_type":"original","volume":37,"supplementarymaterial":"no","month":"06","type":"journal_article","ddc":["500"],"file":[{"creator":"dernst","file_name":"2026_EuropJourAppliedMath_Portinale.pdf","access_level":"open_access","date_created":"2026-07-23T05:55:03Z","date_updated":"2026-07-23T05:55:03Z","success":1,"checksum":"d038f4d00cbfbde2672c17138eab21c9","file_size":612317,"file_id":"22386","relation":"main_file","content_type":"application/pdf"}],"department":[{"_id":"GradSch"},{"_id":"JaMa"}],"language":[{"iso":"eng"}],"has_accepted_license":"1","file_date_updated":"2026-07-23T05:55:03Z","OA_place":"publisher","scopus_import":"1","publication_identifier":{"issn":["0956-7925"],"eissn":["1469-4425"]},"publisher":"Cambridge University Press","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2026-10-28T23:31:05Z","das_tickbox":"0","DOAJ_listed":"1","title":"Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs","oa":1,"related_material":{"record":[{"relation":"dissertation_contains","id":"20563","status":"public"}]},"day":"01","fulldoi":"https://doi.org/10.1017/s0956792524000810","isi":1,"project":[{"grant_number":"F6504","name":"Taming Complexity in Partial Differential Systems","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2"}],"oa_version":"Published Version","date_published":"2026-06-01T00:00:00Z","abstract":[{"lang":"eng","text":"We prove discrete-to-continuum convergence for dynamical optimal transport on  Zd\r\n -periodic graphs with cost functional having linear growth at infinity. This result provides an answer to a problem left open by Gladbach, Kopfer, Maas, and Portinale (Calc Var Partial Differential Equations 62(5), 2023), where the convergence behaviour of discrete boundary-value dynamical transport problems is proved under the stronger assumption of superlinear growth. Our result extends the known literature to some important classes of examples, such as scaling limits of  1 -Wasserstein transport problems. Similarly to what happens in the quadratic case, the geometry of the graph plays a crucial role in the structure of the limit cost function, as we discuss in the final part of this work, which includes some visual representations."}],"intvolume":"        37","author":[{"first_name":"Lorenzo","last_name":"Portinale","id":"30AD2CBC-F248-11E8-B48F-1D18A9856A87","full_name":"Portinale, Lorenzo"},{"id":"3ebd6ba8-edfb-11eb-afb5-91a9745ba308","full_name":"Quattrocchi, Filippo","last_name":"Quattrocchi","orcid":"0009-0000-9773-1931","first_name":"Filippo"}],"publication_status":"published","issue":"3","researchdata_availability":"no","quality_controlled":"1","doi":"10.1017/s0956792524000810","keyword":["optimal transport","discrete-to-continuum","homogenisation","linear growth","gamma-convergence"],"year":"2026","OA_type":"gold","_id":"18706","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","article_processing_charge":"Yes","PlanS_conform":"1","external_id":{"isi":["001381435800001"]},"citation":{"ama":"Portinale L, Quattrocchi F. Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs. <i>European Journal of Applied Mathematics</i>. 2026;37(3):614-642. doi:<a href=\"https://doi.org/10.1017/s0956792524000810\">10.1017/s0956792524000810</a>","apa":"Portinale, L., &#38; Quattrocchi, F. (2026). Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs. <i>European Journal of Applied Mathematics</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/s0956792524000810\">https://doi.org/10.1017/s0956792524000810</a>","ista":"Portinale L, Quattrocchi F. 2026. Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs. European Journal of Applied Mathematics. 37(3), 614–642.","ieee":"L. Portinale and F. Quattrocchi, “Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs,” <i>European Journal of Applied Mathematics</i>, vol. 37, no. 3. Cambridge University Press, pp. 614–642, 2026.","short":"L. Portinale, F. Quattrocchi, European Journal of Applied Mathematics 37 (2026) 614–642.","mla":"Portinale, Lorenzo, and Filippo Quattrocchi. “Discrete-to-Continuum Limits of Optimal Transport with Linear Growth on Periodic Graphs.” <i>European Journal of Applied Mathematics</i>, vol. 37, no. 3, Cambridge University Press, 2026, pp. 614–42, doi:<a href=\"https://doi.org/10.1017/s0956792524000810\">10.1017/s0956792524000810</a>.","chicago":"Portinale, Lorenzo, and Filippo Quattrocchi. “Discrete-to-Continuum Limits of Optimal Transport with Linear Growth on Periodic Graphs.” <i>European Journal of Applied Mathematics</i>. Cambridge University Press, 2026. <a href=\"https://doi.org/10.1017/s0956792524000810\">https://doi.org/10.1017/s0956792524000810</a>."},"publication":"European Journal of Applied Mathematics"},{"language":[{"iso":"eng"}],"department":[{"_id":"GradSch"},{"_id":"EdHa"}],"file":[{"embargo":"2026-09-11","date_updated":"2026-09-11T22:30:02Z","access_level":"open_access","date_created":"2026-03-12T20:38:52Z","file_name":"2026_Dunajova_Zuzana_Thesis_pdfA.pdf","creator":"zdunajov","content_type":"application/pdf","relation":"main_file","file_id":"21446","file_size":14662770,"checksum":"47ce6a48a0c63f28eca6e64c9ffd2c84"},{"file_size":32961408,"file_id":"21447","checksum":"5dec5afdffd47c2b0b162d0fe1bed925","embargo_to":"open_access","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","relation":"source_file","file_name":"Thesis-Dunajova_source_file.docx","creator":"zdunajov","date_updated":"2026-09-11T22:30:02Z","date_created":"2026-03-12T20:40:18Z","access_level":"closed"}],"ddc":["539","570"],"type":"dissertation","month":"03","acknowledgement":"Finally, I gratefully acknowledge funding from the DOC Fellowship of the Austrian Academy\r\nof Sciences (OeAW): grant agreement 26360.","date_created":"2026-03-11T08:30:49Z","license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","page":"110","publisher":"Institute of Science and Technology Austria","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-076-3"]},"supervisor":[{"first_name":"Edouard B","orcid":"0000-0001-6005-1561","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B"}],"OA_place":"repository","file_date_updated":"2026-09-11T22:30:02Z","corr_author":"1","acknowledged_ssus":[{"_id":"ScienComp"}],"has_accepted_license":"1","alternative_title":["ISTA Thesis"],"title":"Geometry-driven self-organization of migrating cells and chiral filaments","doi_confirm":"1","date_updated":"2026-10-16T08:12:11Z","tmp":{"short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","image":"/images/cc_by_nc_sa.png"},"day":"11","related_material":{"record":[{"status":"public","id":"13314","relation":"part_of_dissertation"},{"status":"public","relation":"research_data","id":"13116"},{"status":"public","relation":"research_data","id":"21439"},{"id":"21427","relation":"part_of_dissertation","status":"public"}]},"oa":1,"author":[{"id":"4B39F286-F248-11E8-B48F-1D18A9856A87","full_name":"Dunajova, Zuzana","last_name":"Dunajova","first_name":"Zuzana"}],"publication_status":"published","abstract":[{"text":"Biological systems, such as cytoskeletal filaments and multicellular collectives, exhibit rich \r\nself-organization driven by their intrinsic activity and physical constraints. Across scales, \r\ngeometry plays a central role: the shape of active units and the structure of their environment \r\nstrongly influence how order emerges in these far-from-equilibrium systems. In this thesis, \r\nwe combine minimal active-matter models with bottom-up in vitro experiments to identify \r\nthe principles by which geometry and activity shape collective behavior in biological matter. \r\nAt the subcellular scale, we investigate how the physical properties of chiral FtsZ filaments \r\ngovern their large-scale organization. Using a mesoscopic model validated by reconstituted \r\nfilament assays, we show that filament shape, intrinsic curvature, and flexibility, together with \r\nactivity-driven straightening, determine whether filaments form chiral rings, polar bands, or \r\nnematic-like states. Our model shows that small changes in filament mechanics produce large \r\nshifts in collective structures, revealing how the geometry of individual filaments amplifies \r\nthrough activity to control patterns relevant for bacterial cytokinesis. \r\nAt the cellular scale, we examine how geometry of the external environment influences \r\ncollective cancer cell migration. Experiments in controlled microfabricated obstacle \r\nenvironments demonstrate that geometric disorder alone can induce a transition from \r\ncollective to single-cell invasion. A minimal model of active particles in disordered geometries \r\nreproduces these effects, demonstrating that cell dissemination results both from local \r\ngeometrical constraints and a global integration of spatial disorder over time. Surprisingly, \r\nthis transition is accompanied by a change in the universality class of interface dynamics, \r\nrevealing that cell-environment interactions can shift the collective behavior of an invasive \r\nfront purely through mechanics.  \r\nIn the last system, we study how cell-intrinsic geometry and chirality affect collective motion \r\nin confined and unconfined settings. Using a minimal model inspired by in vitro experiments, \r\nwe analyze motile cells that exhibit persistent rotation due to intrinsic left-right asymmetry. \r\nIn circular confinement, this simplified chiral model reproduces several experimentally \r\nobserved features within specific parameter regimes. At high densities in unconfined \r\nenvironments, however, intrinsic chirality becomes masked even before the onset of the \r\njamming transition. These results show that single-cell geometric asymmetry does not \r\nnecessarily translate into large-scale chiral flows, offering new insight into how forces and \r\nsymmetries shape collective motion in dense cellular systems. \r\nOverall, this work uncovers how geometric constraints – embedded in the intrinsic \r\narchitecture of an active filament or encoded in the complexity of a microenvironment \r\ncouple to active forces to generate different classes of complex behaviors. ","lang":"eng"}],"date_published":"2026-03-11T00:00:00Z","fulldoi":"https://doi.org/10.15479/AT-ISTA-21423","oa_version":"Published Version","project":[{"_id":"34d75525-11ca-11ed-8bc3-89b6307fee9d","name":"Motile active matter models of migrating cells and chiral filaments","grant_number":"26360"}],"doi":"10.15479/AT-ISTA-21423","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","status":"public","_id":"21423","degree_awarded":"PhD","year":"2026","citation":{"ama":"Dunajova Z. Geometry-driven self-organization of migrating cells and chiral filaments. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21423\">10.15479/AT-ISTA-21423</a>","ista":"Dunajova Z. 2026. Geometry-driven self-organization of migrating cells and chiral filaments. Institute of Science and Technology Austria.","apa":"Dunajova, Z. (2026). <i>Geometry-driven self-organization of migrating cells and chiral filaments</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21423\">https://doi.org/10.15479/AT-ISTA-21423</a>","ieee":"Z. Dunajova, “Geometry-driven self-organization of migrating cells and chiral filaments,” Institute of Science and Technology Austria, 2026.","short":"Z. Dunajova, Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments, Institute of Science and Technology Austria, 2026.","mla":"Dunajova, Zuzana. <i>Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21423\">10.15479/AT-ISTA-21423</a>.","chicago":"Dunajova, Zuzana. “Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21423\">https://doi.org/10.15479/AT-ISTA-21423</a>."},"article_processing_charge":"No"},{"doi":"10.15479/AT-ISTA-21439","date_published":"2026-03-12T00:00:00Z","fulldoi":"https://doi.org/10.15479/AT-ISTA-21439","project":[{"_id":"34d75525-11ca-11ed-8bc3-89b6307fee9d","name":"Motile active matter models of migrating cells and chiral filaments","grant_number":"26360"}],"oa_version":"Published Version","abstract":[{"lang":"eng","text":"These files contain supplementary movies accompanying the PhD thesis “Geometry-driven self-organization of migrating cells and chiral filaments” by Zuzana Dunajova (2026). The videos provide additional visual material supporting the experiments and results described in the thesis."}],"author":[{"last_name":"Dunajova","full_name":"Dunajova, Zuzana","id":"4B39F286-F248-11E8-B48F-1D18A9856A87","first_name":"Zuzana"}],"article_processing_charge":"No","citation":{"mla":"Dunajova, Zuzana. <i>Supplementary Movies to PhD Thesis “Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21439\">10.15479/AT-ISTA-21439</a>.","chicago":"Dunajova, Zuzana. “Supplementary Movies to PhD Thesis ‘Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21439\">https://doi.org/10.15479/AT-ISTA-21439</a>.","short":"Z. Dunajova, (2026).","apa":"Dunajova, Z. (2026). Supplementary movies to PhD thesis “Geometry-driven self-organization of migrating cells and chiral filaments.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21439\">https://doi.org/10.15479/AT-ISTA-21439</a>","ista":"Dunajova Z. 2026. Supplementary movies to PhD thesis “Geometry-driven self-organization of migrating cells and chiral filaments”, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21439\">10.15479/AT-ISTA-21439</a>.","ieee":"Z. Dunajova, “Supplementary movies to PhD thesis ‘Geometry-driven self-organization of migrating cells and chiral filaments.’” Institute of Science and Technology Austria, 2026.","ama":"Dunajova Z. Supplementary movies to PhD thesis “Geometry-driven self-organization of migrating cells and chiral filaments.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21439\">10.15479/AT-ISTA-21439</a>"},"contributor":[{"last_name":"Tasciyan","id":"4323B49C-F248-11E8-B48F-1D18A9856A87","contributor_type":"researcher","first_name":"Saren","orcid":"0000-0003-1671-393X"},{"id":"40136C2A-F248-11E8-B48F-1D18A9856A87","last_name":"Radler","orcid":"0000-0001-9198-2182 ","contributor_type":"researcher","first_name":"Philipp"}],"year":"2026","OA_type":"free access","_id":"21439","status":"public","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","has_accepted_license":"1","corr_author":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"ScienComp"}],"file_date_updated":"2026-03-11T20:52:39Z","OA_place":"repository","publisher":"Institute of Science and Technology Austria","date_created":"2026-03-11T21:05:20Z","ddc":["570"],"month":"03","type":"research_data","file":[{"creator":"zdunajov","file_name":"Supplementary_movies_Thesis_Dunajova.zip","date_created":"2026-03-11T20:41:28Z","access_level":"open_access","date_updated":"2026-03-11T20:41:28Z","success":1,"checksum":"47809a9a31b748b16e21e92d11ddc87f","file_id":"21440","file_size":154465214,"relation":"main_file","content_type":"application/zip"},{"creator":"zdunajov","file_name":"readme.txt","access_level":"open_access","date_created":"2026-03-11T20:52:39Z","date_updated":"2026-03-11T20:52:39Z","success":1,"checksum":"a64a174bc6abf0a5e77631e4fd121f1f","file_size":2289,"file_id":"21441","relation":"main_file","content_type":"text/plain"}],"department":[{"_id":"GradSch"},{"_id":"EdHa"}],"oa":1,"related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"13314"},{"relation":"used_in_publication","id":"21427","status":"public"},{"status":"public","relation":"used_in_publication","id":"21423"}]},"day":"12","tmp":{"short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","image":"/images/cc_by_nc_sa.png"},"date_updated":"2026-10-28T23:31:08Z","title":"Supplementary movies to PhD thesis “Geometry-driven self-organization of migrating cells and chiral filaments”"},{"fulldoi":"https://doi.org/10.4230/LIPIcs.ITC.2025.4","date_published":"2025-09-08T00:00:00Z","oa_version":"Published Version","publication_status":"published","author":[{"last_name":"Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654"},{"last_name":"Wang","full_name":"Wang, Pengxiang","first_name":"Pengxiang"}],"abstract":[{"lang":"eng","text":"Truncation of cryptographic outputs is a technique that was recently introduced in Baldimtsi et al. [Foteini Baldimtsi et al., 2022]. The general idea is to try out many inputs to some cryptographic algorithm until the output (e.g. a public-key or some hash value) falls into some sparse set and thus can be compressed: by trying out an expected 2^k different inputs one will find an output that starts with k zeros.\r\nUsing such truncation one can for example save substantial gas fees on Blockchains where storing values is very expensive. While [Foteini Baldimtsi et al., 2022] show that truncation preserves the security of the underlying primitive, they only consider a setting without preprocessing. In this work we show that lower bounds on the time-space tradeoff for inverting random functions and permutations also hold with truncation, except for parameters ranges where the bound fails to hold for \"trivial\" reasons.\r\nConcretely, it’s known that any algorithm that inverts a random function or permutation with range N making T queries and using S bits of auxiliary input must satisfy S⋅ T ≥ Nlog N. This lower bound no longer holds in the truncated setting where one must only invert a challenge from a range of size N/2^k, as now one can simply save the replies to all N/2^k challenges, which requires S = log N⋅ N /2^k bits and allows to invert with T = 1 query.\r\nWe show that with truncation, whenever S is somewhat smaller than the log N⋅ N /2^k bits required to store the entire truncated function table, the known S⋅ T ≥ Nlog N lower bound applies."}],"intvolume":"       343","quality_controlled":"1","doi":"10.4230/LIPIcs.ITC.2025.4","conference":{"location":"Santa Barbara, CA, United States","start_date":"2025-08-16","name":"ITC: Information Theoretic Cryptography","end_date":"2025-08-17"},"keyword":["Time-Space Lower Bounds","Blockchains"],"year":"2025","_id":"22007","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"gold","citation":{"ama":"Pietrzak KZ, Wang P. Time-space tradeoffs of truncation with preprocessing. In: <i>6th Conference on Information-Theoretic Cryptography</i>. Vol 343. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2025. doi:<a href=\"https://doi.org/10.4230/LIPIcs.ITC.2025.4\">10.4230/LIPIcs.ITC.2025.4</a>","chicago":"Pietrzak, Krzysztof Z, and Pengxiang Wang. “Time-Space Tradeoffs of Truncation with Preprocessing.” In <i>6th Conference on Information-Theoretic Cryptography</i>, Vol. 343. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2025. <a href=\"https://doi.org/10.4230/LIPIcs.ITC.2025.4\">https://doi.org/10.4230/LIPIcs.ITC.2025.4</a>.","mla":"Pietrzak, Krzysztof Z., and Pengxiang Wang. “Time-Space Tradeoffs of Truncation with Preprocessing.” <i>6th Conference on Information-Theoretic Cryptography</i>, vol. 343, 4:1-4:10, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2025, doi:<a href=\"https://doi.org/10.4230/LIPIcs.ITC.2025.4\">10.4230/LIPIcs.ITC.2025.4</a>.","short":"K.Z. Pietrzak, P. Wang, in:, 6th Conference on Information-Theoretic Cryptography, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2025.","apa":"Pietrzak, K. Z., &#38; Wang, P. (2025). Time-space tradeoffs of truncation with preprocessing. In <i>6th Conference on Information-Theoretic Cryptography</i> (Vol. 343). Santa Barbara, CA, United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.ITC.2025.4\">https://doi.org/10.4230/LIPIcs.ITC.2025.4</a>","ista":"Pietrzak KZ, Wang P. 2025. Time-space tradeoffs of truncation with preprocessing. 6th Conference on Information-Theoretic Cryptography. ITC: Information Theoretic Cryptography, LIPIcs, vol. 343, 4:1-4:10.","ieee":"K. Z. Pietrzak and P. Wang, “Time-space tradeoffs of truncation with preprocessing,” in <i>6th Conference on Information-Theoretic Cryptography</i>, Santa Barbara, CA, United States, 2025, vol. 343."},"article_processing_charge":"Yes","external_id":{"cryptoeprintid":["2025/723"]},"publication":"6th Conference on Information-Theoretic Cryptography","article_number":"4:1-4:10","month":"09","type":"conference","ddc":["000"],"date_created":"2026-06-14T22:01:45Z","volume":343,"department":[{"_id":"KrPi"}],"language":[{"iso":"eng"}],"file":[{"file_size":772046,"file_id":"22118","checksum":"3f791b03df26853342855a9d9581cb58","content_type":"application/pdf","relation":"main_file","file_name":"2025_LIPIcs_Pietrzak.pdf","creator":"dernst","success":1,"date_updated":"2026-06-22T08:54:32Z","date_created":"2026-06-22T08:54:32Z","access_level":"open_access"}],"corr_author":"1","scopus_import":"1","file_date_updated":"2026-06-22T08:54:32Z","OA_place":"publisher","has_accepted_license":"1","alternative_title":["LIPIcs"],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","publication_identifier":{"eissn":["1868-8969"],"isbn":["9783959773850"]},"date_updated":"2026-06-22T08:57:41Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Time-space tradeoffs of truncation with preprocessing","das_tickbox":"0","oa":1,"cryptoeprintid":1,"day":"08"},{"year":"2025","OA_type":"gold","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"20820","external_id":{"arxiv":["2410.14649"]},"article_processing_charge":"No","citation":{"short":"O. Sieberling, D. Kuznedelev, E. Kurtic, D.-A. Alistarh, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 55556–55590.","mla":"Sieberling, Oliver, et al. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 55556–90.","chicago":"Sieberling, Oliver, Denis Kuznedelev, Eldar Kurtic, and Dan-Adrian Alistarh. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” In <i>42nd International Conference on Machine Learning</i>, 267:55556–90. ML Research Press, 2025.","ista":"Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. 2025. EvoPress: Accurate dynamic model compression via evolutionary search. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 55556–55590.","apa":"Sieberling, O., Kuznedelev, D., Kurtic, E., &#38; Alistarh, D.-A. (2025). EvoPress: Accurate dynamic model compression via evolutionary search. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 55556–55590). Vancouver, Canada: ML Research Press.","ieee":"O. Sieberling, D. Kuznedelev, E. Kurtic, and D.-A. Alistarh, “EvoPress: Accurate dynamic model compression via evolutionary search,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 55556–55590.","ama":"Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. EvoPress: Accurate dynamic model compression via evolutionary search. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:55556-55590."},"publication":"42nd International Conference on Machine Learning","date_published":"2025-05-01T00:00:00Z","oa_version":"Published Version","intvolume":"       267","abstract":[{"lang":"eng","text":"The high computational costs of large language models (LLMs) have led to a flurry of research on LLM compression, via methods such as quantization, sparsification, or structured pruning. A new frontier in this area is given by dynamic, non-uniform compression methods, which adjust the compression levels (e.g., sparsity) per-block or even per-layer in order to minimize accuracy loss, while guaranteeing a global compression threshold. Yet, current methods rely on estimating the \"importance\" of a given layer, implicitly assuming that layers contribute independently to the overall compression error. We begin from the motivating observation that this independence assumption does not generally hold for LLM compression: pruning a model further may even significantly recover performance. To address this, we propose EvoPress, a novel evolutionary framework for dynamic LLM compression. By formulating dynamic compression as a general optimization problem, EvoPress identifies optimal compression profiles in a highly efficient manner, and generalizes across diverse models and compression techniques. Via EvoPress, we achieve state-of-the-art performance for dynamic compression of Llama, Mistral, and Phi models, setting new benchmarks for structural pruning (block/layer dropping), unstructured sparsity, and quantization with dynamic bitwidths."}],"author":[{"last_name":"Sieberling","full_name":"Sieberling, Oliver","first_name":"Oliver"},{"full_name":"Kuznedelev, Denis","last_name":"Kuznedelev","first_name":"Denis"},{"first_name":"Eldar","full_name":"Kurtic, Eldar","id":"47beb3a5-07b5-11eb-9b87-b108ec578218","last_name":"Kurtic"},{"orcid":"0000-0003-3650-940X","first_name":"Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","full_name":"Alistarh, Dan-Adrian","last_name":"Alistarh"}],"publication_status":"published","conference":{"end_date":"2025-07-19","location":"Vancouver, Canada","start_date":"2025-07-13","name":"ICML: International Conference on Machine Learning"},"quality_controlled":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2025-12-16T12:34:32Z","title":"EvoPress: Accurate dynamic model compression via evolutionary search","oa":1,"day":"01","volume":267,"page":"55556-55590","date_created":"2025-12-14T23:02:05Z","type":"conference","month":"05","ddc":["000"],"file":[{"file_id":"20828","file_size":908379,"checksum":"1d744fbaeb199b08e8b6f48bc0dd047e","content_type":"application/pdf","relation":"main_file","file_name":"2025_ICML_Sieberling.pdf","creator":"dernst","success":1,"date_updated":"2025-12-16T12:32:40Z","date_created":"2025-12-16T12:32:40Z","access_level":"open_access"}],"language":[{"iso":"eng"}],"arxiv":1,"department":[{"_id":"DaAl"}],"has_accepted_license":"1","alternative_title":["PMLR"],"OA_place":"publisher","file_date_updated":"2025-12-16T12:32:40Z","scopus_import":"1","corr_author":"1","publication_identifier":{"eissn":["2640-3498"]},"publisher":"ML Research Press"},{"oa":1,"day":"01","date_updated":"2025-12-16T12:46:54Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Layer-wise quantization for quantized optimistic dual averaging","OA_place":"publisher","file_date_updated":"2025-12-16T12:45:41Z","scopus_import":"1","has_accepted_license":"1","alternative_title":["PMLR"],"publisher":"ML Research Press","publication_identifier":{"eissn":["2640-3498"]},"ddc":["000"],"type":"conference","month":"05","volume":267,"acknowledgement":"This work was supported by Hasler Foundation Program: Hasler Responsible AI (project number 21043). The research was also sponsored by the Army Research Office and was accomplished under Grant Number W911NF-24-1-0048. This work was further funded by the Swiss National Science Foundation (SNSF) under grant number 200021_205011. We also acknowledge project A11 of the Swiss National Supercomputing Centre (CSCS) for providing computing resources. Dan Alistarh and Ilia Markov were supported in part through the ERC Proofof-Concept grant FastML (Grant Agreement 101158077). Ali Ramezani-Kebrya was supported by the Research Council of Norway through FRIPRO Grant under project number 356103, its Centres of Excellence scheme, Integreat - Norwegian Centre for knowledge-driven machine learning under\r\nproject number 332645 - and its Centre for Research-based Innovation funding scheme (Visual Intelligence under grant no. 309439).","page":"46026-46072","date_created":"2025-12-14T23:02:06Z","arxiv":1,"language":[{"iso":"eng"}],"department":[{"_id":"DaAl"}],"file":[{"checksum":"a7edf0e4304171a3e035842b3aab1704","file_id":"20830","file_size":756213,"relation":"main_file","content_type":"application/pdf","creator":"dernst","file_name":"2025_ICML_Nguyen.pdf","date_created":"2025-12-16T12:45:41Z","access_level":"open_access","date_updated":"2025-12-16T12:45:41Z","success":1}],"citation":{"ama":"Nguyen AD, Markov I, Wu FZ, et al. Layer-wise quantization for quantized optimistic dual averaging. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:46026-46072.","short":"A.D. Nguyen, I. Markov, F.Z. Wu, A. Ramezani-Kebrya, K. Antonakopoulos, D.-A. Alistarh, V. Cevher, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 46026–46072.","chicago":"Nguyen, Anh Duc, Ilia Markov, Frank Zhengqing Wu, Ali Ramezani-Kebrya, Kimon Antonakopoulos, Dan-Adrian Alistarh, and Volkan Cevher. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” In <i>42nd International Conference on Machine Learning</i>, 267:46026–72. ML Research Press, 2025.","mla":"Nguyen, Anh Duc, et al. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 46026–72.","apa":"Nguyen, A. D., Markov, I., Wu, F. Z., Ramezani-Kebrya, A., Antonakopoulos, K., Alistarh, D.-A., &#38; Cevher, V. (2025). Layer-wise quantization for quantized optimistic dual averaging. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 46026–46072). Vancouver, Canada: ML Research Press.","ista":"Nguyen AD, Markov I, Wu FZ, Ramezani-Kebrya A, Antonakopoulos K, Alistarh D-A, Cevher V. 2025. Layer-wise quantization for quantized optimistic dual averaging. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 46026–46072.","ieee":"A. D. Nguyen <i>et al.</i>, “Layer-wise quantization for quantized optimistic dual averaging,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 46026–46072."},"external_id":{"arxiv":["2505.14371"]},"article_processing_charge":"No","publication":"42nd International Conference on Machine Learning","year":"2025","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20821","OA_type":"gold","conference":{"end_date":"2025-07-19","location":"Vancouver, Canada","name":"ICML: International Conference on Machine Learning","start_date":"2025-07-13"},"quality_controlled":"1","date_published":"2025-05-01T00:00:00Z","project":[{"_id":"8e35c14b-16d5-11f0-9cad-a3fc35339161","name":"FastML: Efficient and Cost-Effective Distributed Machine Learning","grant_number":"101158077"}],"oa_version":"Published Version","author":[{"full_name":"Nguyen, Anh Duc","last_name":"Nguyen","first_name":"Anh Duc"},{"first_name":"Ilia","last_name":"Markov","full_name":"Markov, Ilia","id":"D0CF4148-C985-11E9-8066-0BDEE5697425"},{"full_name":"Wu, Frank Zhengqing","last_name":"Wu","first_name":"Frank Zhengqing"},{"first_name":"Ali","last_name":"Ramezani-Kebrya","full_name":"Ramezani-Kebrya, Ali"},{"first_name":"Kimon","last_name":"Antonakopoulos","full_name":"Antonakopoulos, Kimon"},{"first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","last_name":"Alistarh","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","full_name":"Alistarh, Dan-Adrian"},{"full_name":"Cevher, Volkan","last_name":"Cevher","first_name":"Volkan"}],"publication_status":"published","abstract":[{"lang":"eng","text":"Modern deep neural networks exhibit heterogeneity across numerous layers of various types such as residuals, multi-head attention, etc., due to varying structures (dimensions, activation functions, etc.), distinct representation characteristics, which impact predictions. We develop a general layer-wise quantization framework with tight variance and code-length bounds, adapting to the heterogeneities over the course of training. We then apply a new layer-wise quantization technique within distributed variational inequalities (VIs), proposing a novel Quantized Optimistic Dual Averaging (QODA) algorithm with adaptive learning rates, which achieves competitive convergence rates for monotone VIs. We empirically show that QODA achieves up to a 150% speedup over the baselines in end-to-end training time for training Wasserstein GAN on 12+GPUs."}],"intvolume":"       267"},{"publisher":"EMS Press","publication_identifier":{"eissn":["2308-1317"],"issn":["2308-1309"]},"corr_author":"1","OA_place":"publisher","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.4171/jfg/177","open_access":"1"}],"department":[{"_id":"VaKa"}],"language":[{"iso":"eng"}],"month":"11","type":"journal_article","ddc":["500"],"date_created":"2025-12-19T10:15:37Z","article_type":"original","day":"07","oa":1,"DOAJ_listed":"1","title":"Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces","date_updated":"2026-06-18T18:26:33Z","quality_controlled":"1","doi":"10.4171/jfg/177","author":[{"first_name":"Mathieu","full_name":"Helfter, Mathieu","id":"7d296fbe-e2c6-11ee-84d3-d5c2945f9a57","last_name":"Helfter"}],"publication_status":"epub_ahead","abstract":[{"lang":"eng","text":"For every couple of Hausdorff functions ψ and φ verifying some mild assumptions, there exists a compact subset K of the Baire space such that the φ-Hausdorff measure and the ψ-packing measure on K are both finite and positive. Such examples are then embedded in any infinite dimensional Banach space to answer positively a question of Fan on the existence of metric spaces with arbitrary scales."}],"date_published":"2025-11-07T00:00:00Z","fulldoi":"https://doi.org/10.4171/jfg/177","oa_version":"Published Version","publication":"Journal of Fractal Geometry","citation":{"ama":"Helfter M. Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. <i>Journal of Fractal Geometry</i>. 2025. doi:<a href=\"https://doi.org/10.4171/jfg/177\">10.4171/jfg/177</a>","short":"M. Helfter, Journal of Fractal Geometry (2025).","chicago":"Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite Dimensional Banach Spaces.” <i>Journal of Fractal Geometry</i>. EMS Press, 2025. <a href=\"https://doi.org/10.4171/jfg/177\">https://doi.org/10.4171/jfg/177</a>.","mla":"Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite Dimensional Banach Spaces.” <i>Journal of Fractal Geometry</i>, EMS Press, 2025, doi:<a href=\"https://doi.org/10.4171/jfg/177\">10.4171/jfg/177</a>.","ista":"Helfter M. 2025. Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. Journal of Fractal Geometry.","ieee":"M. Helfter, “Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces,” <i>Journal of Fractal Geometry</i>. EMS Press, 2025.","apa":"Helfter, M. (2025). Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. <i>Journal of Fractal Geometry</i>. EMS Press. <a href=\"https://doi.org/10.4171/jfg/177\">https://doi.org/10.4171/jfg/177</a>"},"article_processing_charge":"Yes","_id":"20839","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"gold","year":"2025"},{"oa_version":"Published Version","fulldoi":"https://doi.org/10.15479/AT-ISTA-20842","date_published":"2025-12-22T00:00:00Z","project":[{"_id":"bdb2a702-d553-11ed-ba76-f12e3e5a3bc6","name":"A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics","grant_number":"101087907"}],"month":"12","type":"research_data","date_created":"2025-12-21T14:23:50Z","author":[{"last_name":"Agafonova","full_name":"Agafonova, Sofya","id":"09501ff6-dca7-11ea-a8ae-b3e0b9166e80","first_name":"Sofya","orcid":"0000-0003-0582-2946"}],"department":[{"_id":"GradSch"},{"_id":"OnHo"}],"file":[{"relation":"main_file","content_type":"application/x-zip-compressed","checksum":"7af34e4226a00cdcb7f154272050e217","file_size":146656591,"file_id":"20854","access_level":"open_access","date_created":"2025-12-22T13:45:30Z","date_updated":"2025-12-22T13:45:30Z","success":1,"creator":"sagafono","file_name":"AllData.zip"},{"file_name":"SourceData.zip","creator":"sagafono","success":1,"date_updated":"2025-12-22T13:45:33Z","date_created":"2025-12-22T13:45:33Z","access_level":"open_access","file_size":93470129,"file_id":"20855","checksum":"71806a2ef9fb26ad7b78e04c6754ee4e","content_type":"application/x-zip-compressed","relation":"main_file"},{"file_id":"20856","file_size":461,"checksum":"08facd1b4a102f83e4d99d48a85b258d","content_type":"text/plain","relation":"main_file","file_name":"readme.txt","creator":"sagafono","success":1,"date_updated":"2025-12-22T13:51:09Z","access_level":"open_access","date_created":"2025-12-22T13:51:09Z"}],"abstract":[{"text":"Probing the possibility of entanglement generation through gravity offers a path to tackle the question of whether gravitational fields possess a quantum mechanical nature. A potential realization necessitates systems with low-frequency dynamics at an optimal mass scale, for which the microgram-to-milligram range is a strong contender. Here, after refining a figure-of-merit for the problem, we present a 1-milligram torsional pendulum operating at 18 Hz. We demonstrate laser cooling its motion from room temperature to 240~microkelvins, surpassing by over 20-fold the coldest motions attained for oscillators ranging from micrograms to kilograms. We quantify and contrast the utility of the current approach with other platforms. The achieved performance and large improvement potential highlight milligram-scale torsional pendulums as a powerful platform for precision measurements relevant to future studies at the quantum-gravity interface.","lang":"eng"}],"file_date_updated":"2025-12-22T13:51:09Z","corr_author":"1","has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","doi":"10.15479/AT-ISTA-20842","date_updated":"2026-06-10T08:36:07Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2025","title":"Research Data for: 'One-milligram torsional pendulum toward experiments at the quantum-gravity interface'","status":"public","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","_id":"20842","oa":1,"citation":{"ieee":"S. Agafonova, “Research Data for: ‘One-milligram torsional pendulum toward experiments at the quantum-gravity interface.’” Institute of Science and Technology Austria, 2025.","ista":"Agafonova S. 2025. Research Data for: ‘One-milligram torsional pendulum toward experiments at the quantum-gravity interface’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-20842\">10.15479/AT-ISTA-20842</a>.","apa":"Agafonova, S. (2025). Research Data for: “One-milligram torsional pendulum toward experiments at the quantum-gravity interface.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20842\">https://doi.org/10.15479/AT-ISTA-20842</a>","short":"S. Agafonova, (2025).","mla":"Agafonova, Sofia. <i>Research Data for: “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.”</i> Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20842\">10.15479/AT-ISTA-20842</a>.","chicago":"Agafonova, Sofia. “Research Data for: ‘One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.’” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20842\">https://doi.org/10.15479/AT-ISTA-20842</a>.","ama":"Agafonova S. Research Data for: “One-milligram torsional pendulum toward experiments at the quantum-gravity interface.” 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20842\">10.15479/AT-ISTA-20842</a>"},"article_processing_charge":"No","day":"22","contributor":[{"first_name":"Pere","last_name":"Rosello"},{"first_name":"Manuel","last_name":"Mekonnen"},{"id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","last_name":"Hosten","orcid":"0000-0002-2031-204X","first_name":"Onur","contributor_type":"supervisor"}],"related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"20840"}]}},{"language":[{"iso":"eng"}],"department":[{"_id":"KrPi"}],"main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/375"}],"volume":16269,"acknowledgement":"We thank Rachel Lin for expressing concern about the applicability of “HJL-style” attacks [15] on the construction in [2] during a talk by the first author about [2]. This was the starting point of the investigation that led us to develop the attack in [5, Sec 4.1]. The first author also thanks Hoeteck Wee for sharing his rationale for introducing evasive LWE.\r\nThe first author is supported by the CyStar center of excellence, the VHAR faculty chair, and the C3iHub fellowship. The third author thanks Cystar, IIT Madras, for supporting a visit to IIT Madras during which the collaboration was initiated. The 4th author is partly supported by JST CREST Grant Number JPMJCR22M1.","date_created":"2025-12-21T23:01:33Z","page":"259-290","type":"conference","month":"12","publication_identifier":{"isbn":["9783032122926"],"eissn":["1611-3349"],"issn":["0302-9743"]},"publisher":"Springer Nature","alternative_title":["LNCS"],"OA_place":"repository","scopus_import":"1","title":"Zeroizing attacks against evasive and circular evasive LWE","date_updated":"2025-12-29T11:51:13Z","day":"05","oa":1,"abstract":[{"text":"We develop new attacks against the Evasive LWE family of assumptions, in both the public and private-coin regime. To the best of our knowledge, ours are the first attacks against Evasive LWE in the public-coin regime, for any instantiation from the family. Our attacks are summarized below.\r\n\r\nPublic-Coin Attacks.\r\n1.The recent work by Hseih, Lin and Luo [17] constructed the first Attribute Based Encryption (ABE) for unbounded depth circuits by relying on the “circular” evasive LWE assumption. This assumption has been popularly considered as a safe, public-coin instance of Evasive LWE in contrast to its “private-coin” cousins (for instance, see [10, 11]).\r\nWe provide the first attack against this assumption, challenging the widely held belief that this is a public-coin assumption.\r\n2. We demonstrate a counter-example against vanilla public-coin evasive LWE by Wee [26] in an unnatural parameter regime. Our attack crucially relies on the error in the pre-condition being larger than the error in the post-condition, necessitating a refinement of the assumption.\r\n\r\nPrivate-Coin Attacks.\r\n1. The recent work by Agrawal, Kumari and Yamada [2] constructed the first functional encryption scheme for pseudorandom functionalities (PRFE) and extended this to obfuscation for pseudorandom functionalities (PRIO) [4] by relying on private-coin evasive LWE. We provide a new attack against the assumption stated in the first posting of their work (subsequently refined to avoid these attacks).\r\n2. The recent work by Branco et al. [8] (concurrently to [4]) provides a construction of obfuscation for pseudorandom functionalities by relying on private-coin evasive LWE. We provide a new attack against their stated assumption.\r\n3. Branco et al. [8] showed that there exist contrived, “self-referential” classes of pseudorandom functionalities for which pseudorandom obfuscation cannot exist. We extend their techniques to develop an analogous result for pseudorandom functional encryption.\r\n\r\nWhile Evasive LWE was developed to specifically avoid “zeroizing attacks”, our work shows that in certain settings, such attacks can still apply.","lang":"eng"}],"intvolume":"     16269","publication_status":"published","author":[{"first_name":"Shweta","last_name":"Agrawal","full_name":"Agrawal, Shweta"},{"full_name":"Modi, Anuja","last_name":"Modi","first_name":"Anuja"},{"last_name":"Yadav","full_name":"Yadav, Anshu","id":"dc8f1524-403e-11ee-bf07-9649ad996e21","first_name":"Anshu"},{"full_name":"Yamada, Shota","last_name":"Yamada","first_name":"Shota"}],"date_published":"2025-12-05T00:00:00Z","fulldoi":"https://doi.org/10.1007/978-3-032-12293-3_9","oa_version":"Preprint","conference":{"end_date":"2025-12-05","name":"TCC: Theory of Cryptography","start_date":"2025-12-01","location":"Aarhus, Denmark"},"doi":"10.1007/978-3-032-12293-3_9","quality_controlled":"1","OA_type":"green","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"20845","year":"2025","publication":"23rd International Conference on Theory of Cryptography","article_processing_charge":"No","citation":{"ieee":"S. Agrawal, A. Modi, A. Yadav, and S. Yamada, “Zeroizing attacks against evasive and circular evasive LWE,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16269, pp. 259–290.","apa":"Agrawal, S., Modi, A., Yadav, A., &#38; Yamada, S. (2025). Zeroizing attacks against evasive and circular evasive LWE. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16269, pp. 259–290). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">https://doi.org/10.1007/978-3-032-12293-3_9</a>","ista":"Agrawal S, Modi A, Yadav A, Yamada S. 2025. Zeroizing attacks against evasive and circular evasive LWE. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16269, 259–290.","short":"S. Agrawal, A. Modi, A. Yadav, S. Yamada, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 259–290.","chicago":"Agrawal, Shweta, Anuja Modi, Anshu Yadav, and Shota Yamada. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” In <i>23rd International Conference on Theory of Cryptography</i>, 16269:259–90. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">https://doi.org/10.1007/978-3-032-12293-3_9</a>.","mla":"Agrawal, Shweta, et al. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16269, Springer Nature, 2025, pp. 259–90, doi:<a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">10.1007/978-3-032-12293-3_9</a>.","ama":"Agrawal S, Modi A, Yadav A, Yamada S. Zeroizing attacks against evasive and circular evasive LWE. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16269. Springer Nature; 2025:259-290. doi:<a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">10.1007/978-3-032-12293-3_9</a>"}},{"author":[{"last_name":"Brandt","full_name":"Brandt, Nicholas","first_name":"Nicholas"},{"last_name":"Cueto Noval","full_name":"Cueto Noval, Miguel","id":"ffc563a3-f6e0-11ea-865d-e3cce03d17cc","first_name":"Miguel","orcid":"0000-0002-2505-4246"},{"full_name":"Günther, Christoph Ullrich","id":"ec98511c-eb8e-11eb-b029-edd25d7271a1","last_name":"Günther","first_name":"Christoph Ullrich"},{"last_name":"Ünal","id":"f6b56fb6-dc63-11ee-9dbf-f6780863a85a","full_name":"Ünal, Akin","first_name":"Akin","orcid":"0000-0002-8929-0221"},{"first_name":"Stella","full_name":"Wohnig, Stella","last_name":"Wohnig"}],"publication_status":"published","abstract":[{"text":"CVRFs are PRFs that unify the properties of verifiable and constrained PRFs. Since they were introduced concurrently by Fuchsbauer and Chandran-Raghuraman-Vinayagamurthy in 2014, it has been an open problem to construct CVRFs without using heavy machinery such as multilinear maps, obfuscation or functional encryption.\r\nWe solve this problem by constructing a prefix-constrained verifiable PRF that does not rely on the aforementioned assumptions. Essentially, our construction is a verifiable version of the Goldreich-Goldwasser-Micali PRF. To achieve verifiability we leverage degree-2 algebraic PRGs and bilinear groups. In short, proofs consist of intermediate values of the Goldreich-Goldwasser-Micali PRF raised to the exponents of group elements. These outputs can be verified using pairings since the underlying PRG is of degree 2.\r\nWe prove the selective security of our construction under the Decisional Square Diffie-Hellman (DSDH) assumption and a new assumption, which we dub recursive Decisional Diffie-Hellman (recursive DDH).\r\nWe prove the soundness of recursive DDH in the generic group model assuming the hardness of the Multivariate Quadratic (MQ) problem and a new variant thereof, which we call MQ+.\r\nLast, in terms of applications, we observe that our CVRF is also an exponent (C)VRF in the plain model. Exponent VRFs were recently introduced by Boneh et al. (Eurocrypt’25) with various applications to threshold cryptography in mind. In addition to that, we give further applications for prefix-CVRFs in the blockchain setting, namely, stake-pooling and compressible randomness beacons.","lang":"eng"}],"intvolume":"     16271","fulldoi":"https://doi.org/10.1007/978-3-032-12290-2_16","oa_version":"Preprint","project":[{"grant_number":"F8509","name":"Security and Privacy by Design for Complex Systems","_id":"34a34d57-11ca-11ed-8bc3-a2688a8724e1"}],"date_published":"2025-12-05T00:00:00Z","doi":"10.1007/978-3-032-12290-2_16","conference":{"end_date":"2025-12-05","name":"TCC: Theory of Cryptography","start_date":"2025-12-01","location":"Aarhus, Denmark"},"quality_controlled":"1","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20846","OA_type":"green","year":"2025","publication":"23rd International Conference on Theory of Cryptography","citation":{"apa":"Brandt, N., Cueto Noval, M., Günther, C. U., Ünal, A., &#38; Wohnig, S. (2025). Constrained verifiable random functions without obfuscation and friends. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16271, pp. 478–511). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">https://doi.org/10.1007/978-3-032-12290-2_16</a>","ieee":"N. Brandt, M. Cueto Noval, C. U. Günther, A. Ünal, and S. Wohnig, “Constrained verifiable random functions without obfuscation and friends,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16271, pp. 478–511.","ista":"Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. 2025. Constrained verifiable random functions without obfuscation and friends. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 478–511.","short":"N. Brandt, M. Cueto Noval, C.U. Günther, A. Ünal, S. Wohnig, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 478–511.","mla":"Brandt, Nicholas, et al. “Constrained Verifiable Random Functions without Obfuscation and Friends.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16271, Springer Nature, 2025, pp. 478–511, doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">10.1007/978-3-032-12290-2_16</a>.","chicago":"Brandt, Nicholas, Miguel Cueto Noval, Christoph Ullrich Günther, Akin Ünal, and Stella Wohnig. “Constrained Verifiable Random Functions without Obfuscation and Friends.” In <i>23rd International Conference on Theory of Cryptography</i>, 16271:478–511. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">https://doi.org/10.1007/978-3-032-12290-2_16</a>.","ama":"Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. Constrained verifiable random functions without obfuscation and friends. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16271. Springer Nature; 2025:478-511. doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">10.1007/978-3-032-12290-2_16</a>"},"article_processing_charge":"No","language":[{"iso":"eng"}],"department":[{"_id":"KrPi"}],"main_file_link":[{"url":"https://eprint.iacr.org/2025/1045","open_access":"1"}],"type":"conference","month":"12","acknowledgement":"We thank Jonas Steinbach and Gertjan De Mulder for helpful discussions on BIP 32, Dennis Hofheinz and Julia Kastner for helpful discussions on early prototypes of our CVRF, and Klaus Kraßnitzer for running pairing benchmarks on his MacBook Pro.\r\nChristoph U. Günther: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","volume":16271,"page":"478-511","date_created":"2025-12-21T23:01:34Z","publisher":"Springer Nature","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783032122896"]},"OA_place":"repository","scopus_import":"1","corr_author":"1","alternative_title":["LNCS"],"title":"Constrained verifiable random functions without obfuscation and friends","date_updated":"2025-12-29T11:11:29Z","day":"05","oa":1},{"_id":"20847","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","year":"2025","publication":"Physical Review E","article_number":"065418","citation":{"short":"E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical Review E 112 (2025).","mla":"Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>, vol. 112, no. 6, 065418, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>.","chicago":"Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>.","ista":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. 112(6), 065418.","ieee":"E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter,” <i>Physical Review E</i>, vol. 112, no. 6. American Physical Society, 2025.","apa":"Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., &#38; Waitukaitis, S. R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>","ama":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. 2025;112(6). doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>"},"article_processing_charge":"Yes (via OA deal)","PlanS_conform":"1","external_id":{"arxiv":["2508.05643"]},"publication_status":"published","author":[{"first_name":"Eavan","last_name":"Fitzgerald","id":"2df8ab8f-080d-11ed-979a-bfe651ca3afa","full_name":"Fitzgerald, Eavan"},{"orcid":"0000-0002-1843-3803","first_name":"Cécile","full_name":"Clavaud, Cécile","id":"5f654c5d-04a1-11eb-ab36-ba9ffec58bd8","last_name":"Clavaud"},{"first_name":"Debasish","last_name":"Das","full_name":"Das, Debasish"},{"last_name":"Lenton","id":"a550210f-223c-11ec-8182-e2d45e817efb","full_name":"Lenton, Isaac C","first_name":"Isaac C","orcid":"0000-0002-5010-6984"},{"full_name":"Waitukaitis, Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","last_name":"Waitukaitis","orcid":"0000-0002-2299-3176","first_name":"Scott R"}],"issue":"6","abstract":[{"text":"We report on an experimental active matter system with motion restricted to four cardinal directions. Our particles are magnetite-doped colloidal spheres driven by the Quincke electrorotational instability. The absence of a magnetic field (|𝑩|=0) leads to circular trajectories interspersed with short spontaneous runs. Intermediate fields (|𝑩|≲20mT) linearize the motion along the axis perpendicular to 𝑩. At high magnetic fields, we observe the surprising emergence of a second, distinct linearization along the axis parallel to 𝑩. With numerical simulations, we show that this behavior can be explained by anisotropic magnetic susceptibility.","lang":"eng"}],"intvolume":"       112","oa_version":"Published Version","fulldoi":"https://doi.org/10.1103/1ss8-31rb","project":[{"_id":"bd8eede5-d553-11ed-ba76-eaded0d13485","name":"MixQUIckR: Mixing with QUIncke Rollers","grant_number":"E 298"},{"grant_number":"949120","name":"Tribocharge: a multi-scale approach to an enduring problem in physics","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","call_identifier":"H2020"}],"date_published":"2025-12-01T00:00:00Z","quality_controlled":"1","doi":"10.1103/1ss8-31rb","title":"Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter","date_updated":"2025-12-29T11:19:34Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"day":"01","oa":1,"department":[{"_id":"ScWa"}],"arxiv":1,"language":[{"iso":"eng"}],"file":[{"creator":"dernst","file_name":"2025_PhysReviewE_Fitzgerald.pdf","date_created":"2025-12-29T11:15:42Z","access_level":"open_access","success":1,"date_updated":"2025-12-29T11:15:42Z","checksum":"d593e933f976c3f3cde37ad66539d57d","file_size":2131491,"file_id":"20862","relation":"main_file","content_type":"application/pdf"}],"type":"journal_article","ddc":["530"],"month":"12","date_created":"2025-12-21T23:01:34Z","article_type":"original","volume":112,"acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant\r\nAgreement No. 949120). This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge the crucial contributions of Alexandre Morin in getting the project off the ground, and Jack Merrin for creating the SU-8 deposition protocol used in the construction of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their work on single-particle characterization. ","publisher":"American Physical Society","ec_funded":1,"publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"corr_author":"1","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"scopus_import":"1","OA_place":"publisher","file_date_updated":"2025-12-29T11:15:42Z","has_accepted_license":"1"},{"oa":1,"day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"date_updated":"2025-12-29T11:29:16Z","title":"Mutation–selection–drift balance models of complex diseases","has_accepted_license":"1","scopus_import":"1","file_date_updated":"2025-12-29T11:27:51Z","OA_place":"publisher","publication_identifier":{"eissn":["1943-2631"],"issn":["0016-6731"]},"publisher":"Oxford University Press","acknowledgement":"We thank Nick Barton, Magnus Nordborg, John Novembre, Molly Przeworski, and Himani Sachdeva for many helpful discussions and for comments on the manuscript, and we thank Joshua Schraiber and 2 anonymous reviewers for comments on the manuscript. We also thank members of the Sella, Przeworski and Andolfatto labs at Columbia University, and the Berg, Novembre and Steinrücken labs at the University of Chicago, for feedback on the work at various stages. This work was completed in part with resources provided by the University of Chicago's Research Computing Center. This work was supported by National Institutes of Health F32 grant GM126787 and R35 grant GM151257 to J.J.B. and National Institutes of Health R01 grant GM115889 to G.S.","article_type":"original","volume":231,"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","pmid":1,"date_created":"2025-12-21T23:01:34Z","ddc":["570"],"month":"12","type":"journal_article","file":[{"file_name":"2025_Genetics_Berg.pdf","creator":"dernst","date_updated":"2025-12-29T11:27:51Z","success":1,"access_level":"open_access","date_created":"2025-12-29T11:27:51Z","file_id":"20863","file_size":1182339,"checksum":"b02eb6b78028b8bef435edc8435a8468","content_type":"application/pdf","relation":"main_file"}],"language":[{"iso":"eng"}],"department":[{"_id":"NiBa"}],"external_id":{"pmid":["41073879"]},"article_processing_charge":"Yes (in subscription journal)","citation":{"ama":"Berg JJ, Li X, Riall K, Hayward L, Sella G. Mutation–selection–drift balance models of complex diseases. <i>Genetics</i>. 2025;231(4). doi:<a href=\"https://doi.org/10.1093/genetics/iyaf220\">10.1093/genetics/iyaf220</a>","ista":"Berg JJ, Li X, Riall K, Hayward L, Sella G. 2025. Mutation–selection–drift balance models of complex diseases. Genetics. 231(4), iyaf220.","apa":"Berg, J. J., Li, X., Riall, K., Hayward, L., &#38; Sella, G. (2025). Mutation–selection–drift balance models of complex diseases. <i>Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/genetics/iyaf220\">https://doi.org/10.1093/genetics/iyaf220</a>","ieee":"J. J. Berg, X. Li, K. Riall, L. Hayward, and G. Sella, “Mutation–selection–drift balance models of complex diseases,” <i>Genetics</i>, vol. 231, no. 4. Oxford University Press, 2025.","mla":"Berg, Jeremy J., et al. “Mutation–Selection–Drift Balance Models of Complex Diseases.” <i>Genetics</i>, vol. 231, no. 4, iyaf220, Oxford University Press, 2025, doi:<a href=\"https://doi.org/10.1093/genetics/iyaf220\">10.1093/genetics/iyaf220</a>.","chicago":"Berg, Jeremy J., Xinyi Li, Kellen Riall, Laura Hayward, and Guy Sella. “Mutation–Selection–Drift Balance Models of Complex Diseases.” <i>Genetics</i>. Oxford University Press, 2025. <a href=\"https://doi.org/10.1093/genetics/iyaf220\">https://doi.org/10.1093/genetics/iyaf220</a>.","short":"J.J. Berg, X. Li, K. Riall, L. Hayward, G. Sella, Genetics 231 (2025)."},"article_number":"iyaf220","publication":"Genetics","year":"2025","OA_type":"hybrid","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"20848","doi":"10.1093/genetics/iyaf220","quality_controlled":"1","date_published":"2025-12-01T00:00:00Z","fulldoi":"https://doi.org/10.1093/genetics/iyaf220","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Genetic variation that influences complex disease susceptibility is introduced into the population by mutation and removed by natural selection and genetic drift. This mutation–selection–drift balance (MSDB) shapes the prevalence of a disease and its genetic architecture. To date, however, MSDB has been modeled only for monogenic (Mendelian) diseases. Here, we develop an MSDB model for complex disease susceptibility: we assume that genotype relates to disease risk according to the canonical liability threshold model and that the selection on variants affecting risk stems from the fitness cost of the disease. We focus on diseases that are highly polygenic, entail a substantial fitness cost, and are neither extremely common in the population nor exceedingly rare. The comparison of model predictions with genome-wide association studies and other observations in humans indicates that common genetic variation affecting complex disease susceptibility is little affected by directional selection and instead shaped by pleiotropic stabilizing selection on other traits. In turn, directional selection may exert a more substantial effect on rare, large-effect variants. Our results also suggest that current estimates of disease heritability are likely biased. The model thus provides a better understanding of the evolutionary processes that shape the architecture and prevalence of complex diseases."}],"intvolume":"       231","publication_status":"published","issue":"4","author":[{"first_name":"Jeremy J.","full_name":"Berg, Jeremy J.","last_name":"Berg"},{"last_name":"Li","full_name":"Li, Xinyi","first_name":"Xinyi"},{"last_name":"Riall","full_name":"Riall, Kellen","first_name":"Kellen"},{"last_name":"Hayward","full_name":"Hayward, Laura","id":"fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b","first_name":"Laura"},{"first_name":"Guy","last_name":"Sella","full_name":"Sella, Guy"}]},{"OA_place":"repository","scopus_import":"1","corr_author":"1","publication_identifier":{"eissn":["1366-5812"],"issn":["0010-7514"]},"publisher":"Taylor & Francis","volume":66,"article_type":"original","acknowledgement":"I thank Claudia Di Cesare, Edoardo Iani, Gauri Kotiwale and Wendy Sun for proofreading, Daichi Kashino, Gauri Kotiwale, Sara Mascia, Benjamín Navarette and Joris Witstok for their assistance in preparing some of the Figures, and Richard Ellis and Stephen Blundell for constructive comments. Funded by the European Union (ERC, AGENTS, 101076224).","page":"116-151","date_created":"2025-12-29T12:05:25Z","type":"journal_article","month":"12","arxiv":1,"language":[{"iso":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2511.04843"}],"department":[{"_id":"JoMa"}],"oa":1,"day":"04","date_updated":"2026-04-07T08:44:00Z","title":"JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies","doi":"10.1080/00107514.2025.2586370","quality_controlled":"1","fulldoi":"https://doi.org/10.1080/00107514.2025.2586370","project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization"}],"date_published":"2025-12-04T00:00:00Z","oa_version":"Preprint","abstract":[{"text":"Studies of the distant Universe are providing key insights into our understanding of the formation of galaxies. The advent of the James Webb Space Telescope (JWST) has significantly enhanced our observational capabilities, leading to an expanded redshift frontier, providing unprecedented detail in the characterisation of early galaxies and enabling the discovery of new populations of accreting black holes. This review aims to provide an introduction to the basic processes and components that shape the observed spectra of galaxies, with a focus on their relevance to techniques with which high-redshift galaxies are selected. The review further introduces specific topics that have attracted significant attention in recent literature, including the discovery of highly efficient galaxy formation in the early Universe, the relation between galaxies and the process of reionization, new insights into the formation of the first stars and the enrichment of interstellar gas with heavy elements, and breakthroughs in our understanding of the origins of supermassive black holes.","lang":"eng"}],"intvolume":"        66","author":[{"last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","first_name":"Jorryt J","orcid":"0000-0003-2871-127X"}],"issue":"1-4","publication_status":"published","external_id":{"arxiv":["2511.04843"]},"article_processing_charge":"No","citation":{"ama":"Matthee JJ. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. <i>Contemporary Physics</i>. 2025;66(1-4):116-151. doi:<a href=\"https://doi.org/10.1080/00107514.2025.2586370\">10.1080/00107514.2025.2586370</a>","short":"J.J. Matthee, Contemporary Physics 66 (2025) 116–151.","chicago":"Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” <i>Contemporary Physics</i>. Taylor &#38; Francis, 2025. <a href=\"https://doi.org/10.1080/00107514.2025.2586370\">https://doi.org/10.1080/00107514.2025.2586370</a>.","mla":"Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” <i>Contemporary Physics</i>, vol. 66, no. 1–4, Taylor &#38; Francis, 2025, pp. 116–51, doi:<a href=\"https://doi.org/10.1080/00107514.2025.2586370\">10.1080/00107514.2025.2586370</a>.","ista":"Matthee JJ. 2025. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. Contemporary Physics. 66(1–4), 116–151.","ieee":"J. J. Matthee, “JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies,” <i>Contemporary Physics</i>, vol. 66, no. 1–4. Taylor &#38; Francis, pp. 116–151, 2025.","apa":"Matthee, J. J. (2025). JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. <i>Contemporary Physics</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/00107514.2025.2586370\">https://doi.org/10.1080/00107514.2025.2586370</a>"},"publication":"Contemporary Physics","year":"2025","OA_type":"green","status":"public","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","_id":"20864"},{"type":"journal_article","month":"12","ddc":["000"],"date_created":"2025-12-29T12:07:12Z","acknowledgement":"This work was supported in part by the Austrian Science Fund (FWF) SFB project SpyCoDe 10.55776/F85, by the FWF projects ZK-35 and W1255-N23, and by the ERC Advanced Grant VAMOS 101020093. Open access funding provided by Institute of Science and Technology (IST Austria).","article_type":"original","volume":62,"department":[{"_id":"ToHe"}],"language":[{"iso":"eng"}],"arxiv":1,"file":[{"relation":"main_file","content_type":"application/pdf","checksum":"06ed45a1218ad8464818803ae2968aaf","file_id":"20944","file_size":7117003,"date_created":"2026-01-05T12:26:43Z","access_level":"open_access","date_updated":"2026-01-05T12:26:43Z","success":1,"creator":"dernst","file_name":"2025_ActaInformatica_Bartocci.pdf"}],"corr_author":"1","OA_place":"publisher","file_date_updated":"2026-01-05T12:26:43Z","scopus_import":"1","has_accepted_license":"1","publisher":"Springer Nature","ec_funded":1,"publication_identifier":{"eissn":["1432-0525"],"issn":["0001-5903"]},"date_updated":"2026-01-05T12:27:41Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Hypernode automata","oa":1,"day":"09","related_material":{"record":[{"id":"14405","relation":"earlier_version","status":"public"}]},"fulldoi":"https://doi.org/10.1007/s00236-025-00509-8","date_published":"2025-12-09T00:00:00Z","oa_version":"Published Version","project":[{"call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093"},{"_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","grant_number":"F8502","name":"Interface Theory for Security and Privacy"}],"author":[{"first_name":"Ezio","last_name":"Bartocci","full_name":"Bartocci, Ezio"},{"last_name":"Chalupa","id":"87e34708-d6c6-11ec-9f5b-9391e7be2463","full_name":"Chalupa, Marek","first_name":"Marek"},{"orcid":"0000-0002-2985-7724","first_name":"Thomas A","full_name":"Henzinger, Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger"},{"id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87","full_name":"Nickovic, Dejan","last_name":"Nickovic","first_name":"Dejan"},{"full_name":"Oliveira da Costa, Ana","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4","last_name":"Oliveira da Costa","orcid":"0000-0002-8741-5799","first_name":"Ana"}],"issue":"4","publication_status":"published","intvolume":"        62","abstract":[{"text":"In this work, we present hypernode automata as a specification formalism for hyperproperties of systems whose executions may be misaligned among themselves, such as concurrent systems. These automata consist of nodes labeled with hypernode logic formulas and transitions marked with synchronizing actions. Hypernode logic formulas establish relations between sequences of variable values among different system executions. This logic enables both synchronous and asynchronous analysis of traces. In its asynchronous view on execution traces, hypernode formulas establish relations on the order of value changes for each variable without correlating their timing. In both views, the analysis of different execution traces is synchronized through the transitions of hypernode automata. By combining logic’s declarative nature with automata’s procedural power, hypernode automata seamlessly integrate asynchronicity requirements at the node level with synchronicity between node transitions. We show that the model-checking problem for hypernode automata is decidable for specifications where each node specifies either a synchronous or an asynchronous requirement for the system’s executions, but not both.","lang":"eng"}],"quality_controlled":"1","doi":"10.1007/s00236-025-00509-8","year":"2025","_id":"20866","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","citation":{"chicago":"Bartocci, Ezio, Marek Chalupa, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Hypernode Automata.” <i>Acta Informatica</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>.","mla":"Bartocci, Ezio, et al. “Hypernode Automata.” <i>Acta Informatica</i>, vol. 62, no. 4, 43, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>.","short":"E. Bartocci, M. Chalupa, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, Acta Informatica 62 (2025).","apa":"Bartocci, E., Chalupa, M., Henzinger, T. A., Nickovic, D., &#38; Oliveira da Costa, A. (2025). Hypernode automata. <i>Acta Informatica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>","ista":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025. Hypernode automata. Acta Informatica. 62(4), 43.","ieee":"E. Bartocci, M. Chalupa, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode automata,” <i>Acta Informatica</i>, vol. 62, no. 4. Springer Nature, 2025.","ama":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata. <i>Acta Informatica</i>. 2025;62(4). doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>"},"article_processing_charge":"Yes (via OA deal)","external_id":{"arxiv":["2305.02836"]},"publication":"Acta Informatica","article_number":"43"},{"department":[{"_id":"HeEd"}],"language":[{"iso":"eng"}],"arxiv":1,"file":[{"creator":"dernst","file_name":"2025_AlgebraicGeomTopology_Zava.pdf","access_level":"open_access","date_created":"2026-01-05T12:16:38Z","date_updated":"2026-01-05T12:16:38Z","success":1,"checksum":"1e05b4f17a44500ae1ae1e21bc636f6a","file_id":"20943","file_size":574389,"relation":"main_file","content_type":"application/pdf"}],"type":"journal_article","ddc":["500"],"month":"11","page":"5153-5174","date_created":"2025-12-29T12:09:09Z","acknowledgement":"The author was supported by the FWF Grant, Project number I4245-N35. The author would like to thank Thomas Weighill for the helpful discussions around Theorem 3.10, and Takamitsu Yamauchi for bringing to my attention the fundamental reference [35]. Furthermore, the author\r\nis thankful for the detailed and helpful comments of the reviewer of this manuscript.","article_type":"original","volume":25,"publisher":"Mathematical Sciences Publishers","publication_identifier":{"issn":["1472-2747"],"eissn":["1472-2739"]},"corr_author":"1","file_date_updated":"2026-01-05T12:16:38Z","scopus_import":"1","OA_place":"publisher","has_accepted_license":"1","title":"Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces","date_updated":"2026-01-05T12:19:09Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"day":"20","oa":1,"publication_status":"published","issue":"8","author":[{"id":"c8b3499c-7a77-11eb-b046-aa368cbbf2ad","full_name":"Zava, Nicolò","last_name":"Zava","orcid":"0000-0001-8686-1888","first_name":"Nicolò"}],"abstract":[{"lang":"eng","text":"We discuss the embeddability of subspaces of the Gromov–Hausdorff space, which consists of isometry classes of compact metric spaces endowed with the Gromov–Hausdorff distance, into Hilbert spaces. These embeddings are particularly valuable for applications to topological data analysis. We prove that its subspace consisting of metric spaces with at most n points has asymptotic dimension n(n−1)∕2. Thus, there exists a coarse embedding of that space into a Hilbert space. On the contrary, if the number of points is not bounded, then the subspace cannot be coarsely embedded into any uniformly convex Banach space and so, in particular, into any Hilbert space. Furthermore, we prove that, even if we restrict to finite metric spaces whose diameter is bounded by some constant, the subspace still cannot be bi-Lipschitz embedded into any finite-dimensional Hilbert space. We obtain both nonembeddability results by finding obstructions to coarse and bi-Lipschitz embeddings in families of isometry classes of finite subsets of the real line endowed with the Euclidean–Hausdorff distance."}],"intvolume":"        25","fulldoi":"https://doi.org/10.2140/agt.2025.25.5153","date_published":"2025-11-20T00:00:00Z","project":[{"grant_number":"I04245","name":"Algebraic Footprints of Geometric Features in Homology","call_identifier":"FWF","_id":"26AD5D90-B435-11E9-9278-68D0E5697425"}],"oa_version":"Published Version","quality_controlled":"1","doi":"10.2140/agt.2025.25.5153","_id":"20867","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","OA_type":"diamond","year":"2025","publication":"Algebraic & Geometric Topology","citation":{"ama":"Zava N. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. <i>Algebraic &#38; Geometric Topology</i>. 2025;25(8):5153-5174. doi:<a href=\"https://doi.org/10.2140/agt.2025.25.5153\">10.2140/agt.2025.25.5153</a>","short":"N. Zava, Algebraic &#38; Geometric Topology 25 (2025) 5153–5174.","mla":"Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” <i>Algebraic &#38; Geometric Topology</i>, vol. 25, no. 8, Mathematical Sciences Publishers, 2025, pp. 5153–74, doi:<a href=\"https://doi.org/10.2140/agt.2025.25.5153\">10.2140/agt.2025.25.5153</a>.","chicago":"Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” <i>Algebraic &#38; Geometric Topology</i>. Mathematical Sciences Publishers, 2025. <a href=\"https://doi.org/10.2140/agt.2025.25.5153\">https://doi.org/10.2140/agt.2025.25.5153</a>.","apa":"Zava, N. (2025). Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. <i>Algebraic &#38; Geometric Topology</i>. Mathematical Sciences Publishers. <a href=\"https://doi.org/10.2140/agt.2025.25.5153\">https://doi.org/10.2140/agt.2025.25.5153</a>","ista":"Zava N. 2025. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. Algebraic &#38; Geometric Topology. 25(8), 5153–5174.","ieee":"N. Zava, “Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces,” <i>Algebraic &#38; Geometric Topology</i>, vol. 25, no. 8. Mathematical Sciences Publishers, pp. 5153–5174, 2025."},"PlanS_conform":"1","article_processing_charge":"No","external_id":{"arxiv":["2303.04730"]}},{"doi":"10.1038/s44220-025-00519-y","quality_controlled":"1","issue":"12","author":[{"full_name":"Liang, Chen","last_name":"Liang","first_name":"Chen"},{"first_name":"Jiacan","last_name":"Yuan","full_name":"Yuan, Jiacan"},{"last_name":"Zhang","full_name":"Zhang, Renhe","first_name":"Renhe"},{"full_name":"Tang, Xu","last_name":"Tang","first_name":"Xu"},{"first_name":"Gunter","last_name":"Schumann","full_name":"Schumann, Gunter"},{"full_name":"Hitchen, Esther","last_name":"Hitchen","first_name":"Esther"},{"first_name":"Elli","full_name":"Polemiti, Elli","last_name":"Polemiti"},{"first_name":"Emin","last_name":"Serin","full_name":"Serin, Emin"},{"first_name":"Hedi","full_name":"Kebir, Hedi","last_name":"Kebir"},{"last_name":"Lett","full_name":"Lett, Tristram A.","first_name":"Tristram A."},{"first_name":"Nilakshi","last_name":"Vaidya","full_name":"Vaidya, Nilakshi"},{"first_name":"Jean-Charles","last_name":"Roy","full_name":"Roy, Jean-Charles"},{"first_name":"Henrik","last_name":"Walter","full_name":"Walter, Henrik"},{"first_name":"Andreas","full_name":"Heinz, Andreas","last_name":"Heinz"},{"first_name":"Markus","last_name":"Ralser","full_name":"Ralser, Markus"},{"first_name":"Sven","full_name":"Twardziok, Sven","last_name":"Twardziok"},{"last_name":"Eils","full_name":"Eils, Roland","first_name":"Roland"},{"last_name":"Jentsch","full_name":"Jentsch, Marcel","first_name":"Marcel"},{"last_name":"Taron","full_name":"Taron, Ulrike-Helene","first_name":"Ulrike-Helene"},{"full_name":"Schütz, Tatjana","last_name":"Schütz","first_name":"Tatjana"},{"last_name":"Schepanski","full_name":"Schepanski, Kerstin","first_name":"Kerstin"},{"last_name":"Banaschewski","full_name":"Banaschewski, Tobias","first_name":"Tobias"},{"full_name":"Neidhart, Maja","last_name":"Neidhart","first_name":"Maja"},{"first_name":"Andreas","full_name":"Meyer-Lindenberg, Andreas","last_name":"Meyer-Lindenberg"},{"last_name":"Tost","full_name":"Tost, Heike","first_name":"Heike"},{"full_name":"Holz, Nathalie","last_name":"Holz","first_name":"Nathalie"},{"first_name":"Emanuel","last_name":"Schwarz","full_name":"Schwarz, Emanuel"},{"full_name":"Stringaris, Argyris","last_name":"Stringaris","first_name":"Argyris"},{"full_name":"Christmann, Nina","last_name":"Christmann","first_name":"Nina"},{"first_name":"Karina","full_name":"Janson, Karina","last_name":"Janson"},{"first_name":"Frauke","last_name":"Nees","full_name":"Nees, Frauke"},{"last_name":"Neidhart","full_name":"Neidhart, Maja","first_name":"Maja"},{"last_name":"Seefried","full_name":"Seefried, Beke","first_name":"Beke"},{"last_name":"Aden","full_name":"Aden, Rieke","first_name":"Rieke"},{"first_name":"Ole A.","last_name":"Andreassen","full_name":"Andreassen, Ole A."},{"first_name":"Lars T.","last_name":"Westlye","full_name":"Westlye, Lars T."},{"first_name":"Dennis","last_name":"van der Meer","full_name":"van der Meer, Dennis"},{"first_name":"Sara","last_name":"Fernández-Cabello","full_name":"Fernández-Cabello, Sara"},{"first_name":"Rikka","full_name":"Kjelkenes, Rikka","last_name":"Kjelkenes"},{"full_name":"Ask, Helga","last_name":"Ask","first_name":"Helga"},{"full_name":"Rapp, Michael","last_name":"Rapp","first_name":"Michael"},{"full_name":"Tschorn, Mira","last_name":"Tschorn","first_name":"Mira"},{"first_name":"Sarah Jane","last_name":"Böttger","full_name":"Böttger, Sarah Jane"},{"last_name":"Marquand","full_name":"Marquand, Andre","first_name":"Andre"},{"last_name":"Bernas","full_name":"Bernas, Antoine","first_name":"Antoine"},{"full_name":"Novarino, Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","last_name":"Novarino","orcid":"0000-0002-7673-7178","first_name":"Gaia"},{"last_name":"Slater","full_name":"Slater, Mel","first_name":"Mel"},{"full_name":"Gallego, Jaime","last_name":"Gallego","first_name":"Jaime"},{"last_name":"Pastor","full_name":"Pastor, Álvaro","first_name":"Álvaro"},{"first_name":"Guillem","full_name":"Feixas, Guillem","last_name":"Feixas"},{"full_name":"Eiroa-Orosa, Francisco José","last_name":"Eiroa-Orosa","first_name":"Francisco José"},{"first_name":"Markus M.","full_name":"Nöthen, Markus M.","last_name":"Nöthen"},{"last_name":"Forstner","full_name":"Forstner, Andreas J.","first_name":"Andreas J."},{"last_name":"Claus","full_name":"Claus, Isabelle","first_name":"Isabelle"},{"full_name":"Mathey, Carina","last_name":"Mathey","first_name":"Carina"},{"first_name":"Stefanie","last_name":"Heilmann-Heimbach","full_name":"Heilmann-Heimbach, Stefanie"},{"last_name":"Hoffmann","full_name":"Hoffmann, Per","first_name":"Per"},{"last_name":"Miller","full_name":"Miller, Abigail","first_name":"Abigail"},{"full_name":"Sommer, Peter","last_name":"Sommer","first_name":"Peter"},{"full_name":"Schmitt, Karen","last_name":"Schmitt","first_name":"Karen"},{"last_name":"Wilbertz","full_name":"Wilbertz, Johannes","first_name":"Johannes"},{"first_name":"Myrto","last_name":"Patraskaki","full_name":"Patraskaki, Myrto"},{"full_name":"Jirsa, Viktor","last_name":"Jirsa","first_name":"Viktor"},{"full_name":"Petkoski, Spase","last_name":"Petkoski","first_name":"Spase"},{"full_name":"Athanasiadis, Anastasios-Polykarpos","last_name":"Athanasiadis","first_name":"Anastasios-Polykarpos"},{"last_name":"Spanlang","full_name":"Spanlang, Bernhard","first_name":"Bernhard"},{"first_name":"Charlie","full_name":"Pearmund, Charlie","last_name":"Pearmund"},{"full_name":"Hese, Sören","last_name":"Hese","first_name":"Sören"},{"full_name":"Renner, Paul","last_name":"Renner","first_name":"Paul"},{"last_name":"Jia","full_name":"Jia, Tianye","first_name":"Tianye"},{"full_name":"Chang, Xiao","last_name":"Chang","first_name":"Xiao"},{"first_name":"Yuxiang","full_name":"Dai, Yuxiang","last_name":"Dai"},{"full_name":"Xia, Yunman","last_name":"Xia","first_name":"Yunman"},{"first_name":"Yuzhu","full_name":"Li, Yuzhu","last_name":"Li"},{"last_name":"Zhang","full_name":"Zhang, Yanqing","first_name":"Yanqing"},{"full_name":"Calhoun, Vince","last_name":"Calhoun","first_name":"Vince"},{"first_name":"Paul","last_name":"Thompson","full_name":"Thompson, Paul"},{"first_name":"Nicholas","last_name":"Clinton","full_name":"Clinton, Nicholas"},{"full_name":"Desrivières, Sylvane","last_name":"Desrivières","first_name":"Sylvane"},{"first_name":"Kofoworola","last_name":"Agunbiade","full_name":"Agunbiade, Kofoworola"},{"full_name":"Yu, Xinyang","last_name":"Yu","first_name":"Xinyang"},{"first_name":"Zuo","full_name":"Zhang, Zuo","last_name":"Zhang"},{"last_name":"Chen","full_name":"Chen, Di","first_name":"Di"},{"first_name":"Allan H.","full_name":"Young, Allan H.","last_name":"Young"},{"last_name":"Schwalber","full_name":"Schwalber, Ameli","first_name":"Ameli"},{"full_name":"Köhler, Vanessa","last_name":"Köhler","first_name":"Vanessa"},{"last_name":"Stahl","full_name":"Stahl, Bernd","first_name":"Bernd"},{"last_name":"Ogoh","full_name":"Ogoh, George","first_name":"George"},{"last_name":"Schikowski","full_name":"Schikowski, Tamara","first_name":"Tamara"},{"last_name":"Brandlistuen","full_name":"Brandlistuen, Ragnhild","first_name":"Ragnhild"}],"publication_status":"published","abstract":[{"lang":"eng","text":"Residents of low-latitude megacities face growing vulnerability to humid-heat stress under urbanization and global warming, yet limited research has assessed the morbidity burden of mental and behavioral disorders (MBDs) linked to humid-heat exposures in these cities. Here we quantify the hospital admissions of MBDs in Shanghai, a megacity of over 25 million inhabitants, attributable to humid heat, and project future burdens under various greenhouse gas (GHG)-emission and population scenarios. Humid heat drives a higher morbidity burden than high temperature alone, especially in humid-heat nights. Without population change, the humid-heat-related morbidity burden of MBDs would increase by 68.2% (95% empirical confidence interval 56.7%–81.6%) under the highest-GHG-emission scenario by the 2090s, while 8,465 (95% empirical confidence interval 6,928–10,053) cases would be avoided by reducing emissions to the lowest pathway. With projected population decline, the attributable hospital admissions will decrease toward century’s end. These findings highlight the benefit of GHG mitigation in reducing the growing MBD risks posed by extreme humid heat."}],"intvolume":"         3","fulldoi":"https://doi.org/10.1038/s44220-025-00519-y","oa_version":"None","project":[{"_id":"349d1832-11ca-11ed-8bc3-d79b574010e0","grant_number":"101057429","name":"Reducing the impact of major environmental challenges on mental health"}],"date_published":"2025-12-01T00:00:00Z","publication":"Nature Mental Health","citation":{"ama":"Liang C, Yuan J, Zhang R, et al. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. 2025;3(12):1532-1544. doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>","chicago":"Liang, Chen, Jiacan Yuan, Renhe Zhang, Xu Tang, Gunter Schumann, Esther Hitchen, Elli Polemiti, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>.","mla":"Liang, Chen, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>, vol. 3, no. 12, Springer Nature, 2025, pp. 1532–44, doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>.","short":"C. Liang, J. Yuan, R. Zhang, X. Tang, G. Schumann, E. Hitchen, E. Polemiti, E. Serin, H. Kebir, T.A. Lett, N. Vaidya, J.-C. Roy, H. Walter, A. Heinz, M. Ralser, S. Twardziok, R. Eils, M. Jentsch, U.-H. Taron, T. Schütz, K. Schepanski, T. Banaschewski, M. Neidhart, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris, N. Christmann, K. Janson, F. Nees, M. Neidhart, B. Seefried, R. Aden, O.A. Andreassen, L.T. Westlye, D. van der Meer, S. Fernández-Cabello, R. Kjelkenes, H. Ask, M. Rapp, M. Tschorn, S.J. Böttger, A. Marquand, A. Bernas, G. Novarino, M. Slater, J. Gallego, Á. Pastor, G. Feixas, F.J. Eiroa-Orosa, M.M. Nöthen, A.J. Forstner, I. Claus, C. Mathey, S. Heilmann-Heimbach, P. Hoffmann, A. Miller, P. Sommer, K. Schmitt, J. Wilbertz, M. Patraskaki, V. Jirsa, S. Petkoski, A.-P. Athanasiadis, B. Spanlang, C. Pearmund, S. Hese, P. Renner, T. Jia, X. Chang, Y. Dai, Y. Xia, Y. Li, Y. Zhang, V. Calhoun, P. Thompson, N. Clinton, S. Desrivières, K. Agunbiade, X. Yu, Z. Zhang, D. Chen, A.H. Young, A. Schwalber, V. Köhler, B. Stahl, G. Ogoh, T. Schikowski, R. Brandlistuen, Nature Mental Health 3 (2025) 1532–1544.","apa":"Liang, C., Yuan, J., Zhang, R., Tang, X., Schumann, G., Hitchen, E., … Brandlistuen, R. (2025). Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>","ieee":"C. Liang <i>et al.</i>, “Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai,” <i>Nature Mental Health</i>, vol. 3, no. 12. Springer Nature, pp. 1532–1544, 2025.","ista":"Liang C, Yuan J, Zhang R, Tang X, Schumann G, Hitchen E, Polemiti E, Serin E, Kebir H, Lett TA, Vaidya N, Roy J-C, Walter H, Heinz A, Ralser M, Twardziok S, Eils R, Jentsch M, Taron U-H, Schütz T, Schepanski K, Banaschewski T, Neidhart M, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Christmann N, Janson K, Nees F, Neidhart M, Seefried B, Aden R, Andreassen OA, Westlye LT, van der Meer D, Fernández-Cabello S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger SJ, Marquand A, Bernas A, Novarino G, Slater M, Gallego J, Pastor Á, Feixas G, Eiroa-Orosa FJ, Nöthen MM, Forstner AJ, Claus I, Mathey C, Heilmann-Heimbach S, Hoffmann P, Miller A, Sommer P, Schmitt K, Wilbertz J, Patraskaki M, Jirsa V, Petkoski S, Athanasiadis A-P, Spanlang B, Pearmund C, Hese S, Renner P, Jia T, Chang X, Dai Y, Xia Y, Li Y, Zhang Y, Calhoun V, Thompson P, Clinton N, Desrivières S, Agunbiade K, Yu X, Zhang Z, Chen D, Young AH, Schwalber A, Köhler V, Stahl B, Ogoh G, Schikowski T, Brandlistuen R. 2025. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. 3(12), 1532–1544."},"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"20868","OA_type":"closed access","year":"2025","publisher":"Springer Nature","publication_identifier":{"issn":["2731-6076"]},"scopus_import":"1","language":[{"iso":"eng"}],"department":[{"_id":"GaNo"}],"type":"journal_article","month":"12","acknowledgement":"This research was supported by the National Natural Science Foundation of China (grants 42288101 and 42175066) and Shanghai International Science and Technology Partnership Project (grant 21230780200). G.S. is supported by the China Brain Project (grant 2025ZD0215100), the National Natural Science Foundation of China (grant 82150710554), the Chinese National Key Project (grant 2023YFE0199700), the National Natural Science Foundation of China (grant W2541022) and the EC Horizon Europe: environMENTAL project.","volume":3,"article_type":"original","page":"1532-1544","date_created":"2025-12-29T12:11:28Z","day":"01","title":"Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai","date_updated":"2026-01-05T12:02:29Z"},{"language":[{"iso":"eng"}],"department":[{"_id":"NiBa"}],"acknowledgement":"Thank you to Doug Schemske and Nick Barton forcritically reviewing the manuscript, Beatriz Pablo Car-mona for assisting with data collection, Melinda Pickupand Eva Cereghetti for seedlings, and Louise Arathoon,Ksenia Khudiakova, Georg Rieckh, Daria Shiplina, andAnja Westram for help with experimental maintenance.We sincerely thank the Associate Editor Brenda Grewelland two anonymous reviewers for their thoughtfulcomments and suggestions, which substantially improved the clarity and quality of our manuscript. C.B. receivedfunding from the European Union's Horizon 2020 researchand innovation programme under the Marie Skłodowska‐Curie Grant Agreement No. 754411","volume":112,"article_type":"original","date_created":"2025-12-29T12:14:26Z","pmid":1,"month":"12","type":"journal_article","publication_identifier":{"eissn":["1537-2197"],"issn":["0002-9122"]},"ec_funded":1,"publisher":"Wiley","scopus_import":"1","title":"Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors","date_updated":"2026-01-05T11:56:22Z","related_material":{"link":[{"url":"https://github.com/Alex-Fuster/hybrids_drought","relation":"software"}]},"day":"01","intvolume":"       112","abstract":[{"text":"Premise: What maintains trait divergence in the face of gene flow? Two varieties of wild snapdragon (Antirrhinum majus) characterized by divergent flower color hybridize in their native range. Selection on flower color genes is indicated by sharp clines, but the selective agents have not been demonstrated. Although previous work has focused on pollinators, pigmentation genes can also contribute to abiotic stress tolerance. We hypothesized that pigmentation in A. majus mediates stress tolerance, which could contribute to hybrid zone maintenance through parental niche divergence or hybrid maladaptation. Specifically, we tested whether morphotype mediates drought tolerance in an experiment comparing magenta-flowered var. pseudomajus, yellow-flowered var. striatum, and their pink-flowered hybrid cross.\r\nMethods: We experimentally compared drought tolerance of each morphotype from allopatric crosses within and between varieties using three greenhouse treatments. Control plants were watered as needed, while drought-treated plants were watered half as often, either from the transplant stage (“early” drought), or from flowering onset (“late” drought).\r\nResults: Parental morphotypes responded identically to drought in fitness and most phenotypic traits. However, hybrids had lower survival (14%) under late drought stress than parental morphotypes (70%). All hybrids that flowered in the late drought treatment died, compared to ~20% of flowering parental morphotypes.\r\nConclusions: Hybrid maladaptation to abiotic stress could potentially contribute to flower color divergence in the face of gene flow in A. majus. Further research should test the relevance of our results to field conditions and explicitly probe the role of flower color genes in drought tolerance.","lang":"eng"}],"publication_status":"published","author":[{"full_name":"Fuster‐Calvo, Alexandre","last_name":"Fuster‐Calvo","first_name":"Alexandre"},{"full_name":"Jaworski, Coline C.","last_name":"Jaworski","first_name":"Coline C."},{"orcid":"0000-0002-8511-0254","first_name":"Thomas","full_name":"Ellis, Thomas","id":"3153D6D4-F248-11E8-B48F-1D18A9856A87","last_name":"Ellis"},{"orcid":"0000-0002-7354-8574","first_name":"Carina","full_name":"Baskett, Carina","id":"3B4A7CE2-F248-11E8-B48F-1D18A9856A87","last_name":"Baskett"}],"issue":"12","fulldoi":"https://doi.org/10.1002/ajb2.70129","date_published":"2025-12-01T00:00:00Z","project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"oa_version":"None","doi":"10.1002/ajb2.70129","quality_controlled":"1","OA_type":"closed access","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"20869","year":"2025","article_number":"e70129","publication":"American Journal of Botany","external_id":{"pmid":["41327576 "]},"article_processing_charge":"No","citation":{"short":"A. Fuster‐Calvo, C.C. Jaworski, T. Ellis, C. Baskett, American Journal of Botany 112 (2025).","chicago":"Fuster‐Calvo, Alexandre, Coline C. Jaworski, Thomas Ellis, and Carina Baskett. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>.","mla":"Fuster‐Calvo, Alexandre, et al. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>, vol. 112, no. 12, e70129, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>.","ista":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. 2025. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. American Journal of Botany. 112(12), e70129.","apa":"Fuster‐Calvo, A., Jaworski, C. C., Ellis, T., &#38; Baskett, C. (2025). Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. Wiley. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>","ieee":"A. Fuster‐Calvo, C. C. Jaworski, T. Ellis, and C. Baskett, “Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors,” <i>American Journal of Botany</i>, vol. 112, no. 12. Wiley, 2025.","ama":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. 2025;112(12). doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>"}},{"language":[{"iso":"eng"}],"publication_status":"published","author":[{"first_name":"Victoria","full_name":"Stopa, Victoria","last_name":"Stopa"},{"last_name":"Sopić","full_name":"Sopić, Miron","first_name":"Miron"},{"first_name":"Guanliang","full_name":"Li, Guanliang","last_name":"Li"},{"full_name":"Sluimer, Judith","last_name":"Sluimer","first_name":"Judith"},{"last_name":"Basílio","full_name":"Basílio, José","first_name":"José"},{"first_name":"Sander W.","last_name":"van der Laan","full_name":"van der Laan, Sander W."},{"last_name":"Kreil","full_name":"Kreil, David P.","first_name":"David P."},{"full_name":"Devaux, Yvan","last_name":"Devaux","first_name":"Yvan"},{"first_name":"Bernhard","id":"e6cab3de-17f6-11ed-9210-c1e42e045e9d","full_name":"Hochreiter, Bernhard","last_name":"Hochreiter"}],"department":[{"_id":"Bio"}],"abstract":[{"text":"RNA sequencing (RNA-seq) methodologies have evolved rapidly, offering powerful tools to study gene expression, transcriptome dynamics, and molecular mechanisms in various biological contexts. However, the complexity of these approaches poses challenges in data interpretation, sensitivity, and applicability. This chapter provides a comprehensive overview of RNA-seq methodologies, highlighting their advantages, limitations, and applications, particularly in cardiovascular research. Bulk RNA sequencing enables high-throughput gene expression profiling but lacks the resolution to capture cellular heterogeneity and spatial context. Direct RNA sequencing preserves native RNA modifications, offering insights into post-transcriptional regulation, though it remains technically challenging. Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) bridge these gaps by resolving transcriptomic complexity at the cellular level and within tissue architecture, providing crucial insights into disease mechanisms such as atherosclerosis. By summarizing the strengths and limitations of these methodologies, this chapter aims to guide researchers in selecting the most suitable transcriptomic approach for their studies, ultimately advancing precision medicine and biomarker discovery in cardiovascular disease.","lang":"eng"}],"oa_version":"None","fulldoi":"https://doi.org/10.1016/b978-0-443-33064-3.00016-5","date_published":"2025-10-24T00:00:00Z","type":"book_chapter","month":"10","date_created":"2025-12-29T12:16:22Z","page":"131-172","publisher":"Elsevier","publication_identifier":{"isbn":["9780443330643"]},"doi":"10.1016/b978-0-443-33064-3.00016-5","quality_controlled":"1","scopus_import":"1","title":"Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20870","OA_type":"closed access","date_updated":"2026-01-05T11:49:54Z","year":"2025","day":"24","publication":"Transcriptomics in Atherosclerosis","editor":[{"first_name":"Yvan","full_name":"Devaux, Yvan","last_name":"Devaux"},{"last_name":"Sopic","full_name":"Sopic, Miron","first_name":"Miron"}],"citation":{"chicago":"Stopa, Victoria, Miron Sopić, Guanliang Li, Judith Sluimer, José Basílio, Sander W. van der Laan, David P. Kreil, Yvan Devaux, and Bernhard Hochreiter. “Essentials of Transcriptomic Methods: Navigating through RNA Sequencing and Beyond.” In <i>Transcriptomics in Atherosclerosis</i>, edited by Yvan Devaux and Miron Sopic, 131–72. Elsevier, 2025. <a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">https://doi.org/10.1016/b978-0-443-33064-3.00016-5</a>.","mla":"Stopa, Victoria, et al. “Essentials of Transcriptomic Methods: Navigating through RNA Sequencing and Beyond.” <i>Transcriptomics in Atherosclerosis</i>, edited by Yvan Devaux and Miron Sopic, Elsevier, 2025, pp. 131–72, doi:<a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">10.1016/b978-0-443-33064-3.00016-5</a>.","short":"V. Stopa, M. Sopić, G. Li, J. Sluimer, J. Basílio, S.W. van der Laan, D.P. Kreil, Y. Devaux, B. Hochreiter, in:, Y. Devaux, M. Sopic (Eds.), Transcriptomics in Atherosclerosis, Elsevier, 2025, pp. 131–172.","apa":"Stopa, V., Sopić, M., Li, G., Sluimer, J., Basílio, J., van der Laan, S. W., … Hochreiter, B. (2025). Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond. In Y. Devaux &#38; M. Sopic (Eds.), <i>Transcriptomics in Atherosclerosis</i> (pp. 131–172). Elsevier. <a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">https://doi.org/10.1016/b978-0-443-33064-3.00016-5</a>","ista":"Stopa V, Sopić M, Li G, Sluimer J, Basílio J, van der Laan SW, Kreil DP, Devaux Y, Hochreiter B. 2025.Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond. In: Transcriptomics in Atherosclerosis. , 131–172.","ieee":"V. Stopa <i>et al.</i>, “Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond,” in <i>Transcriptomics in Atherosclerosis</i>, Y. Devaux and M. Sopic, Eds. Elsevier, 2025, pp. 131–172.","ama":"Stopa V, Sopić M, Li G, et al. Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond. In: Devaux Y, Sopic M, eds. <i>Transcriptomics in Atherosclerosis</i>. Elsevier; 2025:131-172. doi:<a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">10.1016/b978-0-443-33064-3.00016-5</a>"},"article_processing_charge":"No"},{"department":[{"_id":"BjHo"}],"language":[{"iso":"eng"}],"month":"12","type":"journal_article","date_created":"2026-01-04T23:01:34Z","volume":37,"acknowledgement":"The authors are thankful for the financial support provided by the Ministry of Education, India, and MNNIT Allahabad, as well as for the necessary equipment, computing facilities, and overall support to carry out this study.","article_type":"original","publisher":"AIP Publishing","publication_identifier":{"eissn":["1089-7666"],"issn":["1070-6631"]},"scopus_import":"1","title":"Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation","date_updated":"2026-01-05T10:54:15Z","day":"01","publication_status":"published","issue":"12","author":[{"last_name":"Khatoon","full_name":"Khatoon, Bushra","first_name":"Bushra"},{"full_name":"Chaudhary, Vikas K.","last_name":"Chaudhary","first_name":"Vikas K."},{"first_name":"Shoaib","last_name":"Kamil","full_name":"Kamil, Shoaib","id":"185a19af-dc7d-11ea-9b2f-8eb2201959e9"},{"last_name":"Hasan","full_name":"Hasan, Shabih Ul","first_name":"Shabih Ul"},{"first_name":"M. Siraj","full_name":"Alam, M. Siraj","last_name":"Alam"}],"intvolume":"        37","abstract":[{"lang":"eng","text":"The current work focuses on the performance of hydrodynamics and mass transfer in a microchannel. A hydrodynamic model is developed for a gas–liquid (CO2–water) system and slug flow pattern. For the first time in literature, a concept of pulsating velocity input is introduced in an enhanced cross-T-junction microchannel to study the mass transfer using the physical absorption mechanism in ANSYS FLUENT R2 2024. The mass transfer model is associated with the hydrodynamic model and some user-defined functions in FLUENT. This work demonstrates that incorporating obstructions and applying trapezoidal and sinusoidal wave inputs improve the CO2 absorption rate. The obtained data are further compared with the plain T-junction microchannel in terms of mass transfer coefficient. Solubility of CO2 in three different solvents (ethyl alcohol, water, and ethylene glycol) has been revealed in an enhanced cross T-junction microchannel at two different temperatures, i.e., 298.15 and 303.15 K. The numerical simulations illustrate that an increase in temperature has an adverse effect on the mass transfer rate."}],"fulldoi":"https://doi.org/10.1063/5.0303132","date_published":"2025-12-01T00:00:00Z","oa_version":"None","quality_controlled":"1","doi":"10.1063/5.0303132","_id":"20928","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","OA_type":"closed access","year":"2025","publication":"Physics of Fluids","article_number":"122012","citation":{"apa":"Khatoon, B., Chaudhary, V. K., Kamil, S., Hasan, S. U., &#38; Alam, M. S. (2025). Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation. <i>Physics of Fluids</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0303132\">https://doi.org/10.1063/5.0303132</a>","ista":"Khatoon B, Chaudhary VK, Kamil S, Hasan SU, Alam MS. 2025. Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation. Physics of Fluids. 37(12), 122012.","ieee":"B. Khatoon, V. K. Chaudhary, S. Kamil, S. U. Hasan, and M. S. Alam, “Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation,” <i>Physics of Fluids</i>, vol. 37, no. 12. AIP Publishing, 2025.","chicago":"Khatoon, Bushra, Vikas K. Chaudhary, Shoaib Kamil, Shabih Ul Hasan, and M. Siraj Alam. “Enhanced Mass Transfer in Microgeometry Using Pulsating Velocity Inputs: Hydrodynamic Analysis and Numerical Simulation.” <i>Physics of Fluids</i>. AIP Publishing, 2025. <a href=\"https://doi.org/10.1063/5.0303132\">https://doi.org/10.1063/5.0303132</a>.","mla":"Khatoon, Bushra, et al. “Enhanced Mass Transfer in Microgeometry Using Pulsating Velocity Inputs: Hydrodynamic Analysis and Numerical Simulation.” <i>Physics of Fluids</i>, vol. 37, no. 12, 122012, AIP Publishing, 2025, doi:<a href=\"https://doi.org/10.1063/5.0303132\">10.1063/5.0303132</a>.","short":"B. Khatoon, V.K. Chaudhary, S. Kamil, S.U. Hasan, M.S. Alam, Physics of Fluids 37 (2025).","ama":"Khatoon B, Chaudhary VK, Kamil S, Hasan SU, Alam MS. Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation. <i>Physics of Fluids</i>. 2025;37(12). doi:<a href=\"https://doi.org/10.1063/5.0303132\">10.1063/5.0303132</a>"},"article_processing_charge":"No"},{"article_number":"11355","publication":"Nature Communications","article_processing_charge":"Yes","PlanS_conform":"1","external_id":{"pmid":["41381452"]},"citation":{"ama":"Artan M, Schön H, de Bono M. Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-66409-0\">10.1038/s41467-025-66409-0</a>","ieee":"M. Artan, H. Schön, and M. de Bono, “Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","apa":"Artan, M., Schön, H., &#38; de Bono, M. (2025). Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-66409-0\">https://doi.org/10.1038/s41467-025-66409-0</a>","ista":"Artan M, Schön H, de Bono M. 2025. Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. Nature Communications. 16, 11355.","mla":"Artan, Murat, et al. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>, vol. 16, 11355, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-66409-0\">10.1038/s41467-025-66409-0</a>.","chicago":"Artan, Murat, Hanna Schön, and Mario de Bono. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-66409-0\">https://doi.org/10.1038/s41467-025-66409-0</a>.","short":"M. Artan, H. Schön, M. de Bono, Nature Communications 16 (2025)."},"OA_type":"gold","_id":"20929","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2025","quality_controlled":"1","doi":"10.1038/s41467-025-66409-0","abstract":[{"text":"Insulin/insulin-like growth factor signaling inhibits FOXO transcription factors to control development, homeostasis, and aging. Here, we use proximity labeling to identify proteins interacting with the C. elegans FOXO DAF-16. We show that in well-fed, unstressed animals harboring active insulin signaling, DAF-16 forms a complex with the PAR-1/MARK serine/threonine kinase, a key regulator of cell polarity. PAR-1 inhibits DAF-16 accumulation and promotes DAF-16 phosphorylation at S249, at a conserved motif that PAR-1/human MARK2 phosphorylates in vitro. DAF-2 insulin-like receptor signaling stimulates DAF-16 S249 phosphorylation, suggesting DAF-2 activates PAR-1. DAF-2 also promotes PAR-1 expression by inhibiting DAF-16. PAR-1 knockdown, or DAF-16 S249A, prolong lifespan, whereas phosphomimetic DAF-16 S249D suppresses the longevity of daf-2 mutants. At low insulin signaling, DAF-16 proximity labeling highlights transcription factors, chromatin regulators, and DNA repair proteins. One interactor, the zinc finger/homeobox protein ZFH-2/ZFHX3, forms a complex with DAF-16 and prolongs lifespan. Our work provides entry points for hypothesis-driven studies of FOXO function and longevity.","lang":"eng"}],"intvolume":"        16","author":[{"first_name":"Murat","orcid":"0000-0001-8945-6992","last_name":"Artan","full_name":"Artan, Murat","id":"C407B586-6052-11E9-B3AE-7006E6697425"},{"first_name":"Hanna","last_name":"Schön","full_name":"Schön, Hanna","id":"C8E17EDC-D7AA-11E9-B7B7-45ECE5697425"},{"orcid":"0000-0001-8347-0443","first_name":"Mario","id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","full_name":"De Bono, Mario","last_name":"De Bono"}],"publication_status":"published","fulldoi":"https://doi.org/10.1038/s41467-025-66409-0","project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"_id":"23870BE8-32DE-11EA-91FC-C7463DDC885E","name":"Molecular mechanisms of neural circuit function","grant_number":"209504/A/17/Z"}],"date_published":"2025-12-11T00:00:00Z","oa_version":"Published Version","day":"11","oa":1,"title":"Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins","DOAJ_listed":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2026-05-20T08:10:18Z","APC_amount":"7068 EUR","ec_funded":1,"publication_identifier":{"eissn":["2041-1723"]},"publisher":"Springer Nature","has_accepted_license":"1","acknowledged_ssus":[{"_id":"Bio"}],"corr_author":"1","scopus_import":"1","OA_place":"publisher","file_date_updated":"2026-01-05T10:58:28Z","file":[{"success":1,"date_updated":"2026-01-05T10:58:28Z","date_created":"2026-01-05T10:58:28Z","access_level":"open_access","file_name":"2025_NatureComm_Artan.pdf","creator":"dernst","content_type":"application/pdf","relation":"main_file","file_size":1642352,"file_id":"20941","checksum":"748e2e003b878b85b6048d51621d6aae"}],"department":[{"_id":"MaDe"}],"language":[{"iso":"eng"}],"date_created":"2026-01-04T23:01:34Z","pmid":1,"volume":16,"acknowledgement":"We thank de Bono lab members for helpful comments on the manuscript, and the Mass Spec Facility at the Max Perutz Labs, notably WeiQiang Chen and Markus Hartl, for invaluable discussions and comments on mass spec analyses of worm samples. All LC-MS/MS analyses were performed on instruments of the Vienna BioCenter Core Facilities (VBCF). Microscopy was supported by the Scientific Services Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF). We are grateful to Dr. Geraldine Seydoux (Johns Hopkins University) for worm strains and plasmids, and Dr. Seung-Jae V. Lee (KAIST) for RNAi clones. We are grateful to Ekaterina Lashmanova for designing the daf-16::TbID::mNG::3xFLAG knock-in construct and for her outstanding support in the lab. This work was supported by a Wellcome Investigator Award (209504/A/17/Z) to MdB and an ISTplus Fellowship to MA (Marie Sklodowska-Curie agreement No 754411).","article_type":"original","type":"journal_article","ddc":["570"],"month":"12"}]