---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21747'
abstract:
- lang: eng
text: Entanglement does not always require one particle per party. It was predicted
some 30 years ago that a single photon traversing a beam splitter could violate
a Bell inequality. Although initially debated, single-photon nonlocality was eventually
demonstrated via homodyne measurements. Here, we present an alternate realization
that avoids the complexity of homodyne measurements and potential loopholes in
their implementation. We violate a Bell inequality by performing joint measurements
on two copies of the same single-photon entangled state, where one photon acts
as a phase reference for the other, making it self-referential. We observe CHSH
parameters of 2.71 = 0.09 and 2.23 = 0.07, depending on the joint measurements
implemented. This offers a perspective on single-photon nonlocality and a more
accessible experimental route, potentially applicable to general mode-entangled
states in diverse platforms.
acknowledgement: European Union ERC (101071779 (GRAVITES)); European Union Horizon
2020 Research and Innovation Programme (899368 (EPIQUS)); European Union Horizon
2020 Research and Innovation Programme Marie Sklodowska-Curie (956071 (AppQInfo));
European Union HORIZON Europe Research and Innovation Programme (101135288 (EPIQUE));
FWF Austrian Science Fund (10.55776/COE1 (Quantum Science Austria), 10.55776/F71
(BeyondC), 10.55776/FG5 (Research Group 5)); United States Air Force Office of Scientific
Research (FA9550-21-1-0355 (Q-Trust), FA8655-23-1-7063 (TIQI)).
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Daniel
full_name: Kun, Daniel
last_name: Kun
- first_name: Karl T
full_name: Strömberg, Karl T
id: 68011cd2-da32-11ee-a930-b2774c7aba5f
last_name: Strömberg
- first_name: Borivoje
full_name: Dakić, Borivoje
last_name: Dakić
- first_name: Philip
full_name: Walther, Philip
last_name: Walther
- first_name: Lee A.
full_name: Rozema, Lee A.
last_name: Rozema
citation:
ama: Kun D, Strömberg KT, Dakić B, Walther P, Rozema LA. Testing single-photon entanglement
using self-referential measurements. Optica. 2026;13(4):745-751. doi:10.1364/OPTICA.586172
apa: Kun, D., Strömberg, K. T., Dakić, B., Walther, P., & Rozema, L. A. (2026).
Testing single-photon entanglement using self-referential measurements. Optica.
Optica Publishing Group. https://doi.org/10.1364/OPTICA.586172
chicago: Kun, Daniel, Karl T Strömberg, Borivoje Dakić, Philip Walther, and Lee
A. Rozema. “Testing Single-Photon Entanglement Using Self-Referential Measurements.”
Optica. Optica Publishing Group, 2026. https://doi.org/10.1364/OPTICA.586172.
ieee: D. Kun, K. T. Strömberg, B. Dakić, P. Walther, and L. A. Rozema, “Testing
single-photon entanglement using self-referential measurements,” Optica,
vol. 13, no. 4. Optica Publishing Group, pp. 745–751, 2026.
ista: Kun D, Strömberg KT, Dakić B, Walther P, Rozema LA. 2026. Testing single-photon
entanglement using self-referential measurements. Optica. 13(4), 745–751.
mla: Kun, Daniel, et al. “Testing Single-Photon Entanglement Using Self-Referential
Measurements.” Optica, vol. 13, no. 4, Optica Publishing Group, 2026, pp.
745–51, doi:10.1364/OPTICA.586172.
short: D. Kun, K.T. Strömberg, B. Dakić, P. Walther, L.A. Rozema, Optica 13 (2026)
745–751.
date_created: 2026-04-19T22:07:44Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-05-05T12:05:47Z
day: '20'
ddc:
- '530'
department:
- _id: OnHo
doi: 10.1364/OPTICA.586172
external_id:
arxiv:
- '2511.21819'
file:
- access_level: open_access
checksum: f6e62a93f274e0c07197bf4e457eff31
content_type: application/pdf
creator: dernst
date_created: 2026-05-05T12:01:08Z
date_updated: 2026-05-05T12:01:08Z
file_id: '21799'
file_name: 2026_Optica_Kun.pdf
file_size: 858539
relation: main_file
success: 1
file_date_updated: 2026-05-05T12:01:08Z
has_accepted_license: '1'
intvolume: ' 13'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 745-751
project:
- _id: bdb108fd-d553-11ed-ba76-83dc74a9864f
grant_number: F07105
name: QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration
of Superconducting Quantum Circuits
publication: Optica
publication_identifier:
eissn:
- 2334-2536
publication_status: published
publisher: Optica Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Testing single-photon entanglement using self-referential measurements
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21748'
abstract:
- lang: eng
text: Cells are defined by lipid membranes that differ in their structure across
the tree of life. While the membranes of most bacteria and eukaryotes consist
of single-headed bilayer lipids, the membranes of archaea are composed of mixtures
of single-headed bilayer lipids and double-headed bolalipids. Archaeal bolalipids
can adopt straight or u-shaped conformations, enabling them—together with bilayer
lipids—to control whether membranes form bilayer or monolayer structures. Yet,
the physical principles governing archaeal membranes remain largely unexplored,
especially how membrane structure couples to externally imposed curvature during
membrane remodeling. Here, we perform coarse-grained molecular dynamics simulations
of toroidal vesicles to systematically probe the effects of all relevant combinations
of mean and Gaussian curvatures on shape stability and lipid organization. We
find that soft bilayer membranes can sustain all curvatures induced, whereas rigid
bolalipid monolayer membranes either transition to different vesicle shapes or
rupture. Bilayer-mimicking u-shaped bolalipids and bilayer lipids are spatially
accumulated in regions of high mean membrane curvature independent of Gaussian
curvature. Our work identifies curvature–composition coupling as a physical signature
of archaeal membrane remodeling.
acknowledgement: F.F. acknowledges the financial support from the NOMIS foundation.
M.A. and A.Š. acknowledge the funding from the Volkswagen Foundation (Grant No.
Az 96727). A.Š. acknowledges the funding from ERC Starting Grant “NEPA” (Grant No.
802960) and the Vallee Scholarship.
article_number: '144902'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Felix F
full_name: Frey, Felix F
id: a0270b37-8f1a-11ec-95c7-8e710c59a4f3
last_name: Frey
orcid: 0000-0001-8501-6017
- first_name: Miguel
full_name: Santana de Freitas Amaral, Miguel
id: 4f2d02dd-47a9-11ec-ad10-82820ed3f501
last_name: Santana de Freitas Amaral
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
citation:
ama: 'Frey FF, Santana de Freitas Amaral M, Šarić A. Cracking donuts and sorting
lipids: Geometry controls archaeal membrane stability and lipid organization.
Journal of Chemical Physics. 2026;164(14). doi:10.1063/5.0325170'
apa: 'Frey, F. F., Santana de Freitas Amaral, M., & Šarić, A. (2026). Cracking
donuts and sorting lipids: Geometry controls archaeal membrane stability and lipid
organization. Journal of Chemical Physics. AIP Publishing. https://doi.org/10.1063/5.0325170'
chicago: 'Frey, Felix F, Miguel Santana de Freitas Amaral, and Anđela Šarić. “Cracking
Donuts and Sorting Lipids: Geometry Controls Archaeal Membrane Stability and Lipid
Organization.” Journal of Chemical Physics. AIP Publishing, 2026. https://doi.org/10.1063/5.0325170.'
ieee: 'F. F. Frey, M. Santana de Freitas Amaral, and A. Šarić, “Cracking donuts
and sorting lipids: Geometry controls archaeal membrane stability and lipid organization,”
Journal of Chemical Physics, vol. 164, no. 14. AIP Publishing, 2026.'
ista: 'Frey FF, Santana de Freitas Amaral M, Šarić A. 2026. Cracking donuts and
sorting lipids: Geometry controls archaeal membrane stability and lipid organization.
Journal of Chemical Physics. 164(14), 144902.'
mla: 'Frey, Felix F., et al. “Cracking Donuts and Sorting Lipids: Geometry Controls
Archaeal Membrane Stability and Lipid Organization.” Journal of Chemical Physics,
vol. 164, no. 14, 144902, AIP Publishing, 2026, doi:10.1063/5.0325170.'
short: F.F. Frey, M. Santana de Freitas Amaral, A. Šarić, Journal of Chemical Physics
164 (2026).
corr_author: '1'
date_created: 2026-04-19T22:07:45Z
date_published: 2026-04-14T00:00:00Z
date_updated: 2026-05-05T12:40:41Z
day: '14'
ddc:
- '540'
department:
- _id: AnSa
doi: 10.1063/5.0325170
ec_funded: 1
external_id:
arxiv:
- '2603.15170'
file:
- access_level: open_access
checksum: 2e10c4f4531676e0771ef3730e4b63a9
content_type: application/pdf
creator: dernst
date_created: 2026-05-05T12:35:24Z
date_updated: 2026-05-05T12:35:24Z
file_id: '21801'
file_name: 2026_JourChemPhysics_Frey.pdf
file_size: 8764791
relation: main_file
success: 1
file_date_updated: 2026-05-05T12:35:24Z
has_accepted_license: '1'
intvolume: ' 164'
issue: '14'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: eba2549b-77a9-11ec-83b8-a81e493eae4e
call_identifier: H2020
grant_number: '802960'
name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines'
publication: Journal of Chemical Physics
publication_identifier:
eissn:
- 1089-7690
issn:
- ' 0021-9606'
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
related_material:
record:
- id: '21800'
relation: research_data
status: public
scopus_import: '1'
status: public
title: 'Cracking donuts and sorting lipids: Geometry controls archaeal membrane stability
and lipid organization'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 164
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21749'
abstract:
- lang: eng
text: The collagen triple helix assembles hierarchically into bundled oligomers,
solvated networks, and fibers. Synthetic peptide assemblies, driven by supramolecular
interactions, can form single triple helices through intrahelical amino acid pairs;
however, the principles guiding interhelical associations into higher-order structures
remain unclear. Here, we incorporate cation−π and electrostatic charge pairs to
probe interhelical interactions and elucidate the mechanisms driving triple helix
assembly into fibrils, nanotubes, and nanosheets. Introducing cation−π pairs into
a fibrillating collagen mimetic resulted in D-periodic fibrils with pH-sensitive
gelation. By alternating the presentation of electrostatic and cation−π pairs,
the assembly of another D-periodic fibril featuring inner and outer triple-helical
layers was resolved by cryo electron microscopy to a resolution of 8 Å. At physiological
pH, antiparallel association of these triple helices leads to the formation of
nanotubes. The packing behavior of triple helices correlates with the interhelical
interactions, where parallel associations favor fibril formation and antiparallel
interactions drive nanotube and nanosheet assembly. These self-assembling triple-helical
peptides demonstrate how packing of higher-order structures can be tailored with
supramolecular interactions and establish the relationship of different hierarchical
collagen-mimetic assemblies as pH-dependent.
acknowledgement: The authors acknowledge Crispin Hetherington and L. Tracy Yu for
their technical assistance and insights. This work was funded in part by the National
Science Foundation (CHE 2203937), the National Science Foundation Graduate Research
Fellowship (Grant No. 1842494), the Welch Foundation (C-2141), the Swedish Research
Council (2020-04633), and the NIH (GM122510). This work benefited from using the
SasView application, originally developed under NSF award DMR-0520547. SasView contains
code developed with funding from the European Union’s Horizon 2020 research and
innovation program under the SINE2020 project, Grant Agreement No. 654000. This
work was partly done using the Shared Equipment Authority resources at Rice University.
article_processing_charge: No
article_type: original
author:
- first_name: Carson C.
full_name: Cole, Carson C.
last_name: Cole
- first_name: Mark A.B.
full_name: Kreutzberger, Mark A.B.
last_name: Kreutzberger
- first_name: Kevin
full_name: Klein, Kevin
id: 1e7ede04-9e54-11f0-9ec4-8d4d5563c398
last_name: Klein
- first_name: Kiana A.
full_name: Cahue, Kiana A.
last_name: Cahue
- first_name: Brett H.
full_name: Pogostin, Brett H.
last_name: Pogostin
- first_name: Adam C.
full_name: Farsheed, Adam C.
last_name: Farsheed
- first_name: Joseph W.R.
full_name: Swain, Joseph W.R.
last_name: Swain
- first_name: Thi H.
full_name: Bui, Thi H.
last_name: Bui
- first_name: Arghadip
full_name: Dey, Arghadip
last_name: Dey
- first_name: Jonathan T.
full_name: Makhoul, Jonathan T.
last_name: Makhoul
- first_name: Marija
full_name: Dubackic, Marija
last_name: Dubackic
- first_name: Antara
full_name: Pal, Antara
last_name: Pal
- first_name: Ulf
full_name: Olsson, Ulf
last_name: Olsson
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Edward H.
full_name: Egelman, Edward H.
last_name: Egelman
- first_name: Jeffrey D.
full_name: Hartgerink, Jeffrey D.
last_name: Hartgerink
citation:
ama: Cole CC, Kreutzberger MAB, Klein K, et al. Supramolecular assembly of collagen-mimetic
eptide D-periodic fibrils and nanoassemblies. Biomacromolecules. 2026;27(4):2956-2965.
doi:10.1021/acs.biomac.6c00345
apa: Cole, C. C., Kreutzberger, M. A. B., Klein, K., Cahue, K. A., Pogostin, B.
H., Farsheed, A. C., … Hartgerink, J. D. (2026). Supramolecular assembly of collagen-mimetic
eptide D-periodic fibrils and nanoassemblies. Biomacromolecules. American
Chemical Society. https://doi.org/10.1021/acs.biomac.6c00345
chicago: Cole, Carson C., Mark A.B. Kreutzberger, Kevin Klein, Kiana A. Cahue, Brett
H. Pogostin, Adam C. Farsheed, Joseph W.R. Swain, et al. “Supramolecular Assembly
of Collagen-Mimetic Eptide D-Periodic Fibrils and Nanoassemblies.” Biomacromolecules.
American Chemical Society, 2026. https://doi.org/10.1021/acs.biomac.6c00345.
ieee: C. C. Cole et al., “Supramolecular assembly of collagen-mimetic eptide
D-periodic fibrils and nanoassemblies,” Biomacromolecules, vol. 27, no.
4. American Chemical Society, pp. 2956–2965, 2026.
ista: Cole CC, Kreutzberger MAB, Klein K, Cahue KA, Pogostin BH, Farsheed AC, Swain
JWR, Bui TH, Dey A, Makhoul JT, Dubackic M, Pal A, Olsson U, Šarić A, Egelman
EH, Hartgerink JD. 2026. Supramolecular assembly of collagen-mimetic eptide D-periodic
fibrils and nanoassemblies. Biomacromolecules. 27(4), 2956–2965.
mla: Cole, Carson C., et al. “Supramolecular Assembly of Collagen-Mimetic Eptide
D-Periodic Fibrils and Nanoassemblies.” Biomacromolecules, vol. 27, no.
4, American Chemical Society, 2026, pp. 2956–65, doi:10.1021/acs.biomac.6c00345.
short: C.C. Cole, M.A.B. Kreutzberger, K. Klein, K.A. Cahue, B.H. Pogostin, A.C.
Farsheed, J.W.R. Swain, T.H. Bui, A. Dey, J.T. Makhoul, M. Dubackic, A. Pal, U.
Olsson, A. Šarić, E.H. Egelman, J.D. Hartgerink, Biomacromolecules 27 (2026) 2956–2965.
date_created: 2026-04-19T22:07:46Z
date_published: 2026-04-13T00:00:00Z
date_updated: 2026-05-06T05:43:44Z
day: '13'
department:
- _id: AnSa
doi: 10.1021/acs.biomac.6c00345
intvolume: ' 27'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2025.02.15.637692
month: '04'
oa: 1
oa_version: Preprint
page: 2956-2965
publication: Biomacromolecules
publication_identifier:
eissn:
- 1526-4602
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Supramolecular assembly of collagen-mimetic eptide D-periodic fibrils and nanoassemblies
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21750'
abstract:
- lang: eng
text: Liquid-like superionic conductors, with highly mobile ions in a rigid framework,
offer intrinsically low lattice thermal conductivity without compromising electronic
transport. Argyrodite-type Ag8SnSe6 exhibits a melt-like Ag sublattice that drives
lattice thermal conductivity (κL) below 0.2 watts per meter per kelvin, yet its
low carrier concentration limits the power factor. Here, interstitial Ag atoms
raise the Fermi level into the conduction band, substantially increasing the electron
concentration. Simultaneously, the formation of a secondary Ag2Se phase generates
lattice distortions that enhance phonon scattering. A pronounced mismatch between
electronic (~200 nanometers) and phononic (~0.22 nanometers) mean free paths decouples
charge and heat transport, enabling concurrent suppression of κL and retention
of high electrical conductivity. This coupled electronic-phononic modulation yields
a record ZT of 0.72 at ambient temperature and a peak ZT of 1.1 at 735 kelvins,
with an average ZTavg of 0.72 over 320 to 735 kelvins. A unicouple device achieves
6.3% efficiency under a 357-kelvin gradient, highlighting a practical strategy
for high-performance midtemperature thermoelectrics.
acknowledged_ssus:
- _id: LifeSc
acknowledgement: The Scientific Service Units (SSU) of ISTA supported this research
through resources provided by the Lab Support Facility (LSF). This work was supported
by the National Key R&D Program of China grant 2024YFE0105200 (to C.S.), National
Natural Science Foundation of China grant 12504038 (to M.L.), China Postdoctoral
Science Foundation grant 2023M743151 (to M.L.), Natural Science Foundation of Henan
Province grant 252300421763 (to M.L.), Key Scientific Research Project of Higher
Education Institutions in Henan Province grant 25A140004 (to M.L.), National Natural
Science Foundation of China grant 12204156 (to D.W.), China Postdoctoral Science
Foundation grant 2023TQ0315 and 2023 M743224 (to D.W.), Generalitat de Catalunya
grant 2021SGR00457 (to J.A.), and European Regional Development Fund grants ENE2016-77798-C4-3-R,
PID2020-116093RB-C43, and AEI/10.13039/501100011033 (to A.C.). This work also was
financially supported by ISTA and the Werner Siemens Foundation (to M.I.).
article_number: eaec9073
article_processing_charge: Yes
article_type: original
author:
- first_name: Mengyao
full_name: Li, Mengyao
last_name: Li
- first_name: Xueke
full_name: Zhao, Xueke
last_name: Zhao
- first_name: Yu
full_name: Zhang, Yu
last_name: Zhang
- first_name: Jing
full_name: Yu, Jing
last_name: Yu
- first_name: Xuyang
full_name: Liu, Xuyang
last_name: Liu
- first_name: Mochen
full_name: Jia, Mochen
last_name: Jia
- first_name: Hongzhang
full_name: Song, Hongzhang
last_name: Song
- first_name: Dongyang
full_name: Wang, Dongyang
last_name: Wang
- first_name: Jordi
full_name: Arbiol, Jordi
last_name: Arbiol
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Chongxin
full_name: Shan, Chongxin
last_name: Shan
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
- first_name: Ziyu
full_name: Wang, Ziyu
last_name: Wang
citation:
ama: Li M, Zhao X, Zhang Y, et al. Electronic-phononic decoupling and Fermi-level
tuning enable high thermoelectric performance in Ag8SnSe6. Science Advances.
2026;12(15). doi:10.1126/sciadv.aec9073
apa: Li, M., Zhao, X., Zhang, Y., Yu, J., Liu, X., Jia, M., … Wang, Z. (2026). Electronic-phononic
decoupling and Fermi-level tuning enable high thermoelectric performance in Ag8SnSe6.
Science Advances. AAAS. https://doi.org/10.1126/sciadv.aec9073
chicago: Li, Mengyao, Xueke Zhao, Yu Zhang, Jing Yu, Xuyang Liu, Mochen Jia, Hongzhang
Song, et al. “Electronic-Phononic Decoupling and Fermi-Level Tuning Enable High
Thermoelectric Performance in Ag8SnSe6.” Science Advances. AAAS, 2026.
https://doi.org/10.1126/sciadv.aec9073.
ieee: M. Li et al., “Electronic-phononic decoupling and Fermi-level tuning
enable high thermoelectric performance in Ag8SnSe6,” Science Advances,
vol. 12, no. 15. AAAS, 2026.
ista: Li M, Zhao X, Zhang Y, Yu J, Liu X, Jia M, Song H, Wang D, Arbiol J, Ibáñez
M, Shan C, Cabot A, Wang Z. 2026. Electronic-phononic decoupling and Fermi-level
tuning enable high thermoelectric performance in Ag8SnSe6. Science Advances. 12(15),
eaec9073.
mla: Li, Mengyao, et al. “Electronic-Phononic Decoupling and Fermi-Level Tuning
Enable High Thermoelectric Performance in Ag8SnSe6.” Science Advances,
vol. 12, no. 15, eaec9073, AAAS, 2026, doi:10.1126/sciadv.aec9073.
short: M. Li, X. Zhao, Y. Zhang, J. Yu, X. Liu, M. Jia, H. Song, D. Wang, J. Arbiol,
M. Ibáñez, C. Shan, A. Cabot, Z. Wang, Science Advances 12 (2026).
date_created: 2026-04-19T22:07:47Z
date_published: 2026-04-10T00:00:00Z
date_updated: 2026-05-06T06:08:27Z
day: '10'
ddc:
- '530'
department:
- _id: MaIb
doi: 10.1126/sciadv.aec9073
external_id:
pmid:
- '41961944'
file:
- access_level: open_access
checksum: 9bd4546a23f218972f83164fb21003e1
content_type: application/pdf
creator: dernst
date_created: 2026-05-06T06:06:26Z
date_updated: 2026-05-06T06:06:26Z
file_id: '21802'
file_name: 2026_ScienceAdv_Li.pdf
file_size: 3727993
relation: main_file
success: 1
file_date_updated: 2026-05-06T06:06:26Z
has_accepted_license: '1'
intvolume: ' 12'
issue: '15'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication: Science Advances
publication_identifier:
eissn:
- 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electronic-phononic decoupling and Fermi-level tuning enable high thermoelectric
performance in Ag8SnSe6
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21751'
abstract:
- lang: eng
text: 'We define a certain class of simple varieties over a field k by a constructive
recipe and show how to control their (equivariant) truncating invariants. Consequently,
we prove that on simple varieties: (i) if k = k and char k = p, the p-adic cyclotomic
trace is an equivalence; (ii) if k = Q, the Goodwillie–Jones trace is an isomorphism
in degree zero; (iii) we can control homotopy invariant K-theory KH, which is
equivariantly formal and determined by its topological counterparts. Simple varieties
are quite special, but encompass important singular examples appearing in geometric
representation theory. We, in particular, show that both finite and affine Schubert
varieties for GLn lie in this class, so all the above results hold for them. '
acknowledgement: "This work was supported by a DOC Fellowship of the Austrian Academy
of Sciences at the Institute of Science and Technology Austria (ISTA) and by an
Erasmus+ staff mobility training. It took place during the author’s visit to Laboratoire
de Mathématiques d’Orsay in the course of his PhD at the Institute of Science and
Technology Austria. First and foremost, I would like to thank Matthew Morrow for
discussions, explanations and ideas without which this work would not have been
carried out. I would further like to thank Brian Conrad for providing an amazing
reference on projective cones in appropriate generality, to Vova Sosnilo for carefully
discussing – among other things – the derived nilinvariance for quotients by any
linearly reductive group, and to Adeel Khan, Timo Richarz, Matthias Wendt and Xinwen
Zhu for helpful conversations\r\nabout the results. I would moreover like to thank
the referee for the very useful comments."
article_number: rnag058
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Jakub
full_name: Löwit, Jakub
id: e3b80ae2-eb8e-11eb-b029-9aef4a9108a0
last_name: Löwit
citation:
ama: Löwit J. Equivariant localizing invariants of simple varieties. International
Mathematics Research Notices. 2026;2026(7). doi:10.1093/imrn/rnag058
apa: Löwit, J. (2026). Equivariant localizing invariants of simple varieties. International
Mathematics Research Notices. Oxford University Press. https://doi.org/10.1093/imrn/rnag058
chicago: Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.”
International Mathematics Research Notices. Oxford University Press, 2026.
https://doi.org/10.1093/imrn/rnag058.
ieee: J. Löwit, “Equivariant localizing invariants of simple varieties,” International
Mathematics Research Notices, vol. 2026, no. 7. Oxford University Press, 2026.
ista: Löwit J. 2026. Equivariant localizing invariants of simple varieties. International
Mathematics Research Notices. 2026(7), rnag058.
mla: Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.” International
Mathematics Research Notices, vol. 2026, no. 7, rnag058, Oxford University
Press, 2026, doi:10.1093/imrn/rnag058.
short: J. Löwit, International Mathematics Research Notices 2026 (2026).
corr_author: '1'
date_created: 2026-04-19T22:07:48Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-06T06:36:25Z
day: '01'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1093/imrn/rnag058
external_id:
arxiv:
- '2507.09392'
file:
- access_level: open_access
checksum: 306f4567b7b2dcf38e23f7b55a27514e
content_type: application/pdf
creator: dernst
date_created: 2026-05-06T06:35:05Z
date_updated: 2026-05-06T06:35:05Z
file_id: '21803'
file_name: 2026_IMRN_Loewit.pdf
file_size: 1663246
relation: main_file
success: 1
file_date_updated: 2026-05-06T06:35:05Z
has_accepted_license: '1'
intvolume: ' 2026'
issue: '7'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 901e2a43-16d5-11f0-9cad-9cead34748d6
grant_number: '27004'
name: Arithmetic, geometry, topology and representation theory arising from the
affine Grassmannian
publication: International Mathematics Research Notices
publication_identifier:
eissn:
- 1687-0247
issn:
- 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Equivariant localizing invariants of simple varieties
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2026
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21752'
abstract:
- lang: eng
text: Epithelial tissues function as multicellular communities that preserve tissue
integrity while adapting to diverse environmental stresses by altering cell behaviors.
A striking manifestation of such adaptability is cell plasticity, the ability
of differentiated cells to revert to stem-like states or adopt alternative fates.
Once considered rare and confined to highly regenerative species, cell plasticity
is now recognized across the metazoan tree. In early-branching animals such as
sponges and cnidarians, transdifferentiation and dedifferentiation are integral
to life-cycle transitions and regeneration, whereas in more complex organisms,
these processes typically emerge under stress, including stem cell loss or environmental
perturbations. Here, we examine epithelial cell plasticity through evolutionary,
cellular, and molecular perspectives. Focusing on the intestinal epithelium, we
explore findings from mammalian and Drosophila models showing that progenitors
and even terminally differentiated cells can dedifferentiate in response to external
stimuli that disrupt homeostasis, such as pathogen infection and nutrient fluctuations.
We further discuss conserved mechanisms involving intercellular signaling (e.g.,
Notch, EGFR, and JAK-STAT) and chromatin states primed for reprogramming, modulated
by metabolic cues. Together, these insights position cell plasticity as an ancient
environmental adaptation strategy, shaped by conserved molecular toolkits and
refined by species- and cell lineage-specific innovations.
acknowledgement: This work was supported by JSPS/MEXT KAKENHI (grant numbers JP22J01430
to H.N., JP23H04696, JP23K24025, JP25H02543, JP25K02406 to Y.N.), JST FOREST Program
JPMJFR233E (Y.N.), The Cell Science Research Foundation (Y.N.), and Takeda Science
Foundation (Y.N.).
article_number: '103670'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Hiroki
full_name: Nagai, Hiroki
id: 608df3e6-e2ab-11ed-8890-c9318cec7da4
last_name: Nagai
orcid: 0000-0003-1671-9434
- first_name: Yu Ichiro
full_name: Nakajima, Yu Ichiro
last_name: Nakajima
citation:
ama: 'NAGAI H, Nakajima YI. Epithelial cell plasticity in metazoans: Evolutionary
insights into roles and mechanisms. Seminars in Cell and Developmental Biology.
2026;179-180. doi:10.1016/j.semcdb.2026.103670'
apa: 'NAGAI, H., & Nakajima, Y. I. (2026). Epithelial cell plasticity in metazoans:
Evolutionary insights into roles and mechanisms. Seminars in Cell and Developmental
Biology. Elsevier. https://doi.org/10.1016/j.semcdb.2026.103670'
chicago: 'NAGAI, HIROKI, and Yu Ichiro Nakajima. “Epithelial Cell Plasticity in
Metazoans: Evolutionary Insights into Roles and Mechanisms.” Seminars in Cell
and Developmental Biology. Elsevier, 2026. https://doi.org/10.1016/j.semcdb.2026.103670.'
ieee: 'H. NAGAI and Y. I. Nakajima, “Epithelial cell plasticity in metazoans: Evolutionary
insights into roles and mechanisms,” Seminars in Cell and Developmental Biology,
vol. 179–180. Elsevier, 2026.'
ista: 'NAGAI H, Nakajima YI. 2026. Epithelial cell plasticity in metazoans: Evolutionary
insights into roles and mechanisms. Seminars in Cell and Developmental Biology.
179–180, 103670.'
mla: 'NAGAI, HIROKI, and Yu Ichiro Nakajima. “Epithelial Cell Plasticity in Metazoans:
Evolutionary Insights into Roles and Mechanisms.” Seminars in Cell and Developmental
Biology, vol. 179–180, 103670, Elsevier, 2026, doi:10.1016/j.semcdb.2026.103670.'
short: H. NAGAI, Y.I. Nakajima, Seminars in Cell and Developmental Biology 179–180
(2026).
corr_author: '1'
date_created: 2026-04-19T22:07:49Z
date_published: 2026-05-01T00:00:00Z
date_updated: 2026-04-28T14:11:13Z
day: '01'
ddc:
- '570'
department:
- _id: XiFe
doi: 10.1016/j.semcdb.2026.103670
file:
- access_level: open_access
checksum: 0a0929a045d0cbd964297768833c14ae
content_type: application/pdf
creator: dernst
date_created: 2026-04-28T13:58:47Z
date_updated: 2026-04-28T13:58:47Z
file_id: '21775'
file_name: 2026_SeminarsCellDevBiology_Nagai.pdf
file_size: 1306613
relation: main_file
success: 1
file_date_updated: 2026-04-28T13:58:47Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
publication: Seminars in Cell and Developmental Biology
publication_identifier:
eissn:
- 1096-3634
issn:
- 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Epithelial cell plasticity in metazoans: Evolutionary insights into roles
and mechanisms'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 179-180
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21753'
abstract:
- lang: eng
text: The origin(s) of life (OoL), which has puzzled scientists for centuries, remains
a major scientific challenge in the 21st century. Understanding the processes
relevant to the OoL demands theoretical frameworks that can connect processes
across scales, from microscopic dynamics to emergent levels of organization. While
experimental studies generate a wealth of data, theoretical and computational
approaches provide the structure necessary to interpret and generalize these findings.
In Part 1, we examined the most widely used experimental techniques in the field.
Here, we focus on the mathematical, physical, and computational techniques used
to model phenomena relevant to life’s origin(s). We discuss methods ranging from
quantum chemistry and molecular dynamics to chemical reaction networks, autocatalysis,
and evolutionary modeling, as well as information-theoretic and phylogenetic approaches
that link chemical and biological organization. We further highlight emerging
trends such as synthetic biology, omics-based methods, and laboratory automation
as novel points of contact for theory-experiment integration. Ultimately, we aim
to provide an educational tool that can facilitate more post-disciplinary collaborations
in OoL research by helping scientists understand what they can do about the problem
of life’s origins, rather than telling them how to think about it.
acknowledgement: This work is a collaborative effort of the titled authors as part
of the Origin of Life Early Career Network (OoLEN). We chose to add OoLEN as the
first author to give a better representation of this team effort, rather than listing
any single author as the first author. We hope such a thing can be adopted by others.
We indicate that authors 2–9 (S.A., C.B., C. Blanco, D.B., A.C.-R., C.M., O.M.,
Z.P., and A.V.D.) have made a more distinct contribution. All authors are listed
alphabetically by their last names. We would like to acknowledge all current and
past members of OoLEN for their contributions to our community. In particular, we
would like to acknowledge Evrim Fer, who helped with molecular phylogenetics. We
would like to thank the anonymous referees for reviewing Parts 1 and 2 of this manuscript;
this work was significantly improved through their feedback. S.A. acknowledges support
from NASA through the postdoctoral Program at GSFC. C. Bautista acknowledges support
from “la Caixa” Foundation (ID 100010434) under agreement (LCF/BQ/AA16/11580051)
and by the Fonds de recherche du Québec Nature et technologies (FRQNT) (#274987).
C. Blanco acknowledges support from NASA under award 80NSSC21K0595. D.B. acknowledges
support from Centre national d'études spatiales (CNES) and postdoctoral support
from LGPM-CentralSupélec and NASA under award 80NSSC23K1477. E. Camprubi acknowledges
support from UT System for a STARs award. A.C.-R. acknowledges funding from the
Natural Sciences and Engineering Research Council of Canada (grant number RGPIN/05278–2018),
the Fonds de recherche Nature et Technologies of Québec (grant number 314488), and
the Fondation J. Armand Bombardier Excellence Scholarship. A.C.-R.’s research was
supported by an appointment to the NASA Postdoctoral Program from the NASA Astrobiology
Program administered by Oak Ridge Associated Universities under contract with NASA.
S.F.J. acknowledges support from “la Caixa” Foundation (ID 100010434) and from the
European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska
Curie grant agreement no. 847648 (the fellowship code is LCF/BQ/PI21/11830015).
T.Z.J. acknowledges support from Japan Society for the Promotion of Science (JSPS)
grants-in-aid 18K14354 and 21K14746, a Tokyo Institute of Technology Yoshinori Ohsumi
Fund for Fundamental Research, the Mizuho Foundation for the Promotion of Sciences,
and by the Temporary Assistant Program by the DE&I Section of Science Tokyo. A.K.
acknowledges support from the European Union’s Horizon 2020 research and innovation
program under the Marie Skłodowska-Curie Grant agreement no. 101068029. C.M. acknowledges
support from NASA through the postdoctoral Fellowship Program. The views and conclusions
contained in this document are those of the authors and should not be interpreted
as representing the official policies, either expressed or implied, of NASA. O.M.
acknowledges support from The John Templeton Foundation (#62828) and the Foundation
for Science and Technology (2023.05971.CEECIND). B.K.D.P. acknowledges support from
the NSERC Banting Postdoctoral Fellowship. K.P. acknowledges financial support from
the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s
Excellence Strategy EXC 2181/1 - 390900948 (the Heidelberg STRUCTURES Excellence
Cluster) and is a fellow of the International Max Planck Research School for Astronomy
and Cosmic Physics at the University of Heidelberg (IMPRS-HD).
article_number: '103211'
article_processing_charge: Yes
article_type: original
author:
- first_name: Silke
full_name: Asche, Silke
last_name: Asche
- first_name: Carla
full_name: Bautista, Carla
last_name: Bautista
- first_name: Celia
full_name: Blanco, Celia
last_name: Blanco
- first_name: David
full_name: Boulesteix, David
last_name: Boulesteix
- first_name: Alexandre
full_name: Champagne-Ruel, Alexandre
last_name: Champagne-Ruel
- first_name: Cole
full_name: Mathis, Cole
last_name: Mathis
- first_name: Omer
full_name: Markovitch, Omer
last_name: Markovitch
- first_name: Zhen
full_name: Peng, Zhen
last_name: Peng
- first_name: Avinash Vicholous
full_name: Dass, Avinash Vicholous
last_name: Dass
- first_name: Alyssa
full_name: Adams, Alyssa
last_name: Adams
- first_name: Eloi
full_name: Camprubi, Eloi
last_name: Camprubi
- first_name: Enrico Sandro
full_name: Colizzi, Enrico Sandro
last_name: Colizzi
- first_name: Stephanie
full_name: Colón-Santos, Stephanie
last_name: Colón-Santos
- first_name: Hannah
full_name: Dromiack, Hannah
last_name: Dromiack
- first_name: Valentina
full_name: Erastova, Valentina
last_name: Erastova
- first_name: Amanda
full_name: Garcia, Amanda
last_name: Garcia
- first_name: Ghjuvan
full_name: Grimaud, Ghjuvan
last_name: Grimaud
- first_name: Aaron
full_name: Halpern, Aaron
last_name: Halpern
- first_name: Stuart A.
full_name: Harrison, Stuart A.
last_name: Harrison
- first_name: Seán F.
full_name: Jordan, Seán F.
last_name: Jordan
- first_name: Tony Z.
full_name: Jia, Tony Z.
last_name: Jia
- first_name: Amit
full_name: Kahana, Amit
last_name: Kahana
- first_name: Artemy
full_name: Kolchinsky, Artemy
last_name: Kolchinsky
- first_name: Odin
full_name: Moron-Garcia, Odin
last_name: Moron-Garcia
- first_name: Ryo
full_name: Mizuuchi, Ryo
last_name: Mizuuchi
- first_name: Jingbo
full_name: Nan, Jingbo
last_name: 'Nan'
- first_name: Yuliia
full_name: Orlova, Yuliia
last_name: Orlova
- first_name: Ben K.D.
full_name: Pearce, Ben K.D.
last_name: Pearce
- first_name: Klaus
full_name: Paschek, Klaus
last_name: Paschek
- first_name: Martina
full_name: Preiner, Martina
last_name: Preiner
- first_name: Silvana
full_name: Pinna, Silvana
last_name: Pinna
- first_name: Eduardo
full_name: Rodríguez-Román, Eduardo
last_name: Rodríguez-Román
- first_name: Loraine
full_name: Schwander, Loraine
last_name: Schwander
- first_name: Siddhant
full_name: Sharma, Siddhant
id: 36996868-4916-11f1-8c9d-c0c901467b61
last_name: Sharma
- first_name: Harrison B.
full_name: Smith, Harrison B.
last_name: Smith
- first_name: Andrey
full_name: Vieira, Andrey
last_name: Vieira
- first_name: Joana C.
full_name: Xavier, Joana C.
last_name: Xavier
citation:
ama: 'Asche S, Bautista C, Blanco C, et al. What it takes to solve the origins of
life: An integrated review. Part 2: Theoretical methods and emerging trends. Cell
Reports Physical Science. 2026;7(4). doi:10.1016/j.xcrp.2026.103211'
apa: 'Asche, S., Bautista, C., Blanco, C., Boulesteix, D., Champagne-Ruel, A., Mathis,
C., … Xavier, J. C. (2026). What it takes to solve the origins of life: An integrated
review. Part 2: Theoretical methods and emerging trends. Cell Reports Physical
Science. Elsevier. https://doi.org/10.1016/j.xcrp.2026.103211'
chicago: 'Asche, Silke, Carla Bautista, Celia Blanco, David Boulesteix, Alexandre
Champagne-Ruel, Cole Mathis, Omer Markovitch, et al. “What It Takes to Solve the
Origins of Life: An Integrated Review. Part 2: Theoretical Methods and Emerging
Trends.” Cell Reports Physical Science. Elsevier, 2026. https://doi.org/10.1016/j.xcrp.2026.103211.'
ieee: 'S. Asche et al., “What it takes to solve the origins of life: An integrated
review. Part 2: Theoretical methods and emerging trends,” Cell Reports Physical
Science, vol. 7, no. 4. Elsevier, 2026.'
ista: 'Asche S, Bautista C, Blanco C, Boulesteix D, Champagne-Ruel A, Mathis C,
Markovitch O, Peng Z, Dass AV, Adams A, Camprubi E, Colizzi ES, Colón-Santos S,
Dromiack H, Erastova V, Garcia A, Grimaud G, Halpern A, Harrison SA, Jordan SF,
Jia TZ, Kahana A, Kolchinsky A, Moron-Garcia O, Mizuuchi R, Nan J, Orlova Y, Pearce
BKD, Paschek K, Preiner M, Pinna S, Rodríguez-Román E, Schwander L, Sharma S,
Smith HB, Vieira A, Xavier JC. 2026. What it takes to solve the origins of life:
An integrated review. Part 2: Theoretical methods and emerging trends. Cell Reports
Physical Science. 7(4), 103211.'
mla: 'Asche, Silke, et al. “What It Takes to Solve the Origins of Life: An Integrated
Review. Part 2: Theoretical Methods and Emerging Trends.” Cell Reports Physical
Science, vol. 7, no. 4, 103211, Elsevier, 2026, doi:10.1016/j.xcrp.2026.103211.'
short: S. Asche, C. Bautista, C. Blanco, D. Boulesteix, A. Champagne-Ruel, C. Mathis,
O. Markovitch, Z. Peng, A.V. Dass, A. Adams, E. Camprubi, E.S. Colizzi, S. Colón-Santos,
H. Dromiack, V. Erastova, A. Garcia, G. Grimaud, A. Halpern, S.A. Harrison, S.F.
Jordan, T.Z. Jia, A. Kahana, A. Kolchinsky, O. Moron-Garcia, R. Mizuuchi, J. Nan,
Y. Orlova, B.K.D. Pearce, K. Paschek, M. Preiner, S. Pinna, E. Rodríguez-Román,
L. Schwander, S. Sharma, H.B. Smith, A. Vieira, J.C. Xavier, Cell Reports Physical
Science 7 (2026).
date_created: 2026-04-19T22:07:50Z
date_published: 2026-04-15T00:00:00Z
date_updated: 2026-05-07T12:13:07Z
day: '15'
ddc:
- '570'
doi: 10.1016/j.xcrp.2026.103211
file:
- access_level: open_access
checksum: d5abe5b5bd4b9ee58aa6f4917f688ad9
content_type: application/pdf
creator: dernst
date_created: 2026-05-06T06:48:33Z
date_updated: 2026-05-06T06:48:33Z
file_id: '21804'
file_name: 2026_CellReports_OoLEN.pdf
file_size: 5265320
relation: main_file
success: 1
file_date_updated: 2026-05-06T06:48:33Z
has_accepted_license: '1'
intvolume: ' 7'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Cell Reports Physical Science
publication_identifier:
eissn:
- 2666-3864
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'What it takes to solve the origins of life: An integrated review. Part 2:
Theoretical methods and emerging trends'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21754'
abstract:
- lang: eng
text: The origin(s) of life (OoL), which has puzzled scientists for centuries, remains
a major scientific challenge in the 21st century. Research on OoL spans many disciplines,
including chemistry, physics, biology, planetary sciences, computer science, and
mathematics. The sheer number of different scientific perspectives relevant to
the problem has resulted in the coexistence of diverse tools, techniques, data,
and software in OoL studies. This has made communication between the disciplines
relevant to the OoL extremely difficult because the interpretation of data, analyses,
or standards of evidence varies dramatically. Here, we hope to bridge this wide
field of study by providing common ground via the consolidation of techniques
rather than positing a unifying view on how life emerges. In part 1 of this review,
we cover common experimental techniques that have been used significantly in OoL
studies in recent years, while in part 2, we review theoretical, computational,
and integrative methods. Here, we discuss the use of spectroscopy, spectrometry,
chromatography, microscopy, and sequencing methods for characterizing diverse
materials. We further discuss the role of data repositories in facilitating the
analysis and dissemination of experimental data. This review provides a baseline
expectation and understanding of the analytical aspects of origins’ research.
Ultimately, we aim to provide an educational tool that can facilitate more post-disciplinary
collaborations in OoL research by helping scientists understand what they can
do about the problem of life’s origins, rather than telling them how to think
about it.
acknowledgement: This work is a collaborative effort of the titled authors as part
of the Origin of Life Early Career Network (OoLEN). We chose to add OoLEN as the
first author to give a better representation of this team effort, rather than listing
any single author as the first author. We hope such a thing can be adopted by others.
We indicate that authors 2–9 (S.A., C.B., C. Blanco, D.B., A.C.-R., C.M., O.M.,
Z.P., and A.V.D.) have made a more distinct contribution. All authors are listed
alphabetically by their last names. We would like to acknowledge all current and
past members of OoLEN for their contributions to our community. In particular, we
would like to acknowledge Evrim Fer, who helped with molecular phylogenetics. We
would like to thank the anonymous referees for reviewing Parts 1 and 2 of this manuscript;
this work was significantly improved through their feedback. S.A. acknowledges support
from NASA through the postdoctoral Program at GSFC. C. Bautista acknowledges support
from “la Caixa” Foundation (ID 100010434) under agreement (LCF/BQ/AA16/11580051)
and by the Fonds de recherche du Québec Nature et technologies (FRQNT) (#274987).
C. Blanco acknowledges support from NASA under award 80NSSC21K0595. D.B. acknowledges
support from Centre national d'études spatiales (CNES) and postdoctoral support
from LGPM-CentralSupélec and NASA under award 80NSSC23K1477. E. Camprubi acknowledges
support from UT System for a STARs award. A.C.-R. acknowledges funding from the
Natural Sciences and Engineering Research Council of Canada (grant number RGPIN/05278–2018),
the Fonds de recherche Nature et Technologies of Québec (grant number 314488), and
the Fondation J. Armand Bombardier Excellence Scholarship. A.C.-R.’s research was
supported by an appointment to the NASA Postdoctoral Program from the NASA Astrobiology
Program administered by Oak Ridge Associated Universities under contract with NASA.
S.F.J. acknowledges support from “la Caixa” Foundation (ID 100010434) and from the
European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska
Curie grant agreement no. 847648 (the fellowship code is LCF/BQ/PI21/11830015).
T.Z.J. acknowledges support from Japan Society for the Promotion of Science (JSPS)
grants-in-aid 18K14354 and 21K14746, a Tokyo Institute of Technology Yoshinori Ohsumi
Fund for Fundamental Research, the Mizuho Foundation for the Promotion of Sciences,
and by the Temporary Assistant Program by the DE&I Section of Science Tokyo. A.K.
acknowledges support from the European Union’s Horizon 2020 research and innovation
program under the Marie Skłodowska-Curie Grant agreement no. 101068029. C.M. acknowledges
support from NASA through the postdoctoral Fellowship Program. The views and conclusions
contained in this document are those of the authors and should not be interpreted
as representing the official policies, either expressed or implied, of NASA. O.M.
acknowledges support from The John Templeton Foundation (#62828) and the Foundation
for Science and Technology (2023.05971.CEECIND). B.K.D.P. acknowledges support from
the NSERC Banting Postdoctoral Fellowship. K.P. acknowledges financial support from
the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s
Excellence Strategy EXC 2181/1 - 390900948 (the Heidelberg STRUCTURES Excellence
Cluster) and is a fellow of the International Max Planck Research School for Astronomy
and Cosmic Physics at the University of Heidelberg (IMPRS-HD).
article_number: '103212'
article_processing_charge: Yes
article_type: original
author:
- first_name: Silke
full_name: Asche, Silke
last_name: Asche
- first_name: Carla
full_name: Bautista, Carla
last_name: Bautista
- first_name: Celia
full_name: Blanco, Celia
last_name: Blanco
- first_name: David
full_name: Boulesteix, David
last_name: Boulesteix
- first_name: Alexandre
full_name: Champagne-Ruel, Alexandre
last_name: Champagne-Ruel
- first_name: Cole
full_name: Mathis, Cole
last_name: Mathis
- first_name: Omer
full_name: Markovitch, Omer
last_name: Markovitch
- first_name: Zhen
full_name: Peng, Zhen
last_name: Peng
- first_name: Avinash Vicholous
full_name: Dass, Avinash Vicholous
last_name: Dass
- first_name: Alyssa
full_name: Adams, Alyssa
last_name: Adams
- first_name: Eloi
full_name: Camprubi, Eloi
last_name: Camprubi
- first_name: Enrico Sandro
full_name: Colizzi, Enrico Sandro
last_name: Colizzi
- first_name: Stephanie
full_name: Colón-Santos, Stephanie
last_name: Colón-Santos
- first_name: Hannah
full_name: Dromiack, Hannah
last_name: Dromiack
- first_name: Valentina
full_name: Erastova, Valentina
last_name: Erastova
- first_name: Amanda
full_name: Garcia, Amanda
last_name: Garcia
- first_name: Ghjuvan
full_name: Grimaud, Ghjuvan
last_name: Grimaud
- first_name: Aaron
full_name: Halpern, Aaron
last_name: Halpern
- first_name: Stuart A.
full_name: Harrison, Stuart A.
last_name: Harrison
- first_name: Seán F.
full_name: Jordan, Seán F.
last_name: Jordan
- first_name: Tony Z.
full_name: Jia, Tony Z.
last_name: Jia
- first_name: Amit
full_name: Kahana, Amit
last_name: Kahana
- first_name: Artemy
full_name: Kolchinsky, Artemy
last_name: Kolchinsky
- first_name: Odin
full_name: Moron-Garcia, Odin
last_name: Moron-Garcia
- first_name: Ryo
full_name: Mizuuchi, Ryo
last_name: Mizuuchi
- first_name: Jingbo
full_name: Nan, Jingbo
last_name: 'Nan'
- first_name: Yuliia
full_name: Orlova, Yuliia
last_name: Orlova
- first_name: Ben K.D.
full_name: Pearce, Ben K.D.
last_name: Pearce
- first_name: Klaus
full_name: Paschek, Klaus
last_name: Paschek
- first_name: Martina
full_name: Preiner, Martina
last_name: Preiner
- first_name: Silvana
full_name: Pinna, Silvana
last_name: Pinna
- first_name: Eduardo
full_name: Rodríguez-Román, Eduardo
last_name: Rodríguez-Román
- first_name: Loraine
full_name: Schwander, Loraine
last_name: Schwander
- first_name: Siddhant
full_name: Sharma, Siddhant
id: 36996868-4916-11f1-8c9d-c0c901467b61
last_name: Sharma
- first_name: Harrison B.
full_name: Smith, Harrison B.
last_name: Smith
- first_name: Andrey
full_name: Vieira, Andrey
last_name: Vieira
- first_name: Joana C.
full_name: Xavier, Joana C.
last_name: Xavier
citation:
ama: 'Asche S, Bautista C, Blanco C, et al. What it takes to solve the origin of
life: An integrated review. Part 1–Experimental methods and data repositories.
Cell Reports Physical Science. 2026;7(4). doi:10.1016/j.xcrp.2026.103212'
apa: 'Asche, S., Bautista, C., Blanco, C., Boulesteix, D., Champagne-Ruel, A., Mathis,
C., … Xavier, J. C. (2026). What it takes to solve the origin of life: An integrated
review. Part 1–Experimental methods and data repositories. Cell Reports Physical
Science. Elsevier. https://doi.org/10.1016/j.xcrp.2026.103212'
chicago: 'Asche, Silke, Carla Bautista, Celia Blanco, David Boulesteix, Alexandre
Champagne-Ruel, Cole Mathis, Omer Markovitch, et al. “What It Takes to Solve the
Origin of Life: An Integrated Review. Part 1–Experimental Methods and Data Repositories.”
Cell Reports Physical Science. Elsevier, 2026. https://doi.org/10.1016/j.xcrp.2026.103212.'
ieee: 'S. Asche et al., “What it takes to solve the origin of life: An integrated
review. Part 1–Experimental methods and data repositories,” Cell Reports Physical
Science, vol. 7, no. 4. Elsevier, 2026.'
ista: 'Asche S, Bautista C, Blanco C, Boulesteix D, Champagne-Ruel A, Mathis C,
Markovitch O, Peng Z, Dass AV, Adams A, Camprubi E, Colizzi ES, Colón-Santos S,
Dromiack H, Erastova V, Garcia A, Grimaud G, Halpern A, Harrison SA, Jordan SF,
Jia TZ, Kahana A, Kolchinsky A, Moron-Garcia O, Mizuuchi R, Nan J, Orlova Y, Pearce
BKD, Paschek K, Preiner M, Pinna S, Rodríguez-Román E, Schwander L, Sharma S,
Smith HB, Vieira A, Xavier JC. 2026. What it takes to solve the origin of life:
An integrated review. Part 1–Experimental methods and data repositories. Cell
Reports Physical Science. 7(4), 103212.'
mla: 'Asche, Silke, et al. “What It Takes to Solve the Origin of Life: An Integrated
Review. Part 1–Experimental Methods and Data Repositories.” Cell Reports Physical
Science, vol. 7, no. 4, 103212, Elsevier, 2026, doi:10.1016/j.xcrp.2026.103212.'
short: S. Asche, C. Bautista, C. Blanco, D. Boulesteix, A. Champagne-Ruel, C. Mathis,
O. Markovitch, Z. Peng, A.V. Dass, A. Adams, E. Camprubi, E.S. Colizzi, S. Colón-Santos,
H. Dromiack, V. Erastova, A. Garcia, G. Grimaud, A. Halpern, S.A. Harrison, S.F.
Jordan, T.Z. Jia, A. Kahana, A. Kolchinsky, O. Moron-Garcia, R. Mizuuchi, J. Nan,
Y. Orlova, B.K.D. Pearce, K. Paschek, M. Preiner, S. Pinna, E. Rodríguez-Román,
L. Schwander, S. Sharma, H.B. Smith, A. Vieira, J.C. Xavier, Cell Reports Physical
Science 7 (2026).
date_created: 2026-04-19T22:07:52Z
date_published: 2026-04-15T00:00:00Z
date_updated: 2026-05-07T12:13:25Z
day: '15'
ddc:
- '570'
doi: 10.1016/j.xcrp.2026.103212
file:
- access_level: open_access
checksum: e580d22c2874c0afcbde2d167db7201b
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T05:48:23Z
date_updated: 2026-05-07T05:48:23Z
file_id: '21831'
file_name: 2026_CellREports_OoLEN1.pdf
file_size: 3535247
relation: main_file
success: 1
file_date_updated: 2026-05-07T05:48:23Z
has_accepted_license: '1'
intvolume: ' 7'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Cell Reports Physical Science
publication_identifier:
eissn:
- 2666-3864
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'What it takes to solve the origin of life: An integrated review. Part 1–Experimental
methods and data repositories'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21755'
abstract:
- lang: eng
text: Tropical shallow clouds are a major source of uncertainty in Earth's climate
sensitivity, especially through their spatial arrangement, which global climate
models do not represent. Efforts to understand their organization have partly
relied on classifying observed scenes, identifying four patterns as archetypal
regimes. Here we analyze geostationary satellite imagery of the western tropical
Atlantic using the L‐function, a tool based on point pattern theory that quantifies
cloud organization across spatial scales. Classical examples of the four patterns
show distinct L‐function fingerprints, revealing their characteristic clustering
and regularity scales and aiding physical interpretation. Yet, when evaluating
many scenes at fixed spatial scales, the L‐function distribution lacks the distinct
modes expected from discrete regimes. This is corroborated by analyses of other
organization indices employing diverse approaches, from inter‐cloud nearest‐neighbor
distances to fractal analysis. Implications for the parameterization of mesoscale
cloud organization in climate models are discussed.
acknowledgement: GB was supported by an ICTP Postdoctoral Research Fellowship Agreement.
GM was supported by the CNRS. AC was supported by the European Union's Horizon 2020
research and innovation programme Marie Sklodowska-Curie Grant agreement No 101034413.
LJF acknowledges funding from the NERC Doctoral Training Partnership in Environmental
Research Grant NE/S007474/1. We thank three anonymous reviewers and Jiawei Bao for
their insightful comments, which greatly improved this manuscript.
article_number: e2025GL119921
article_processing_charge: Yes
article_type: original
author:
- first_name: Giovanni
full_name: Biagioli, Giovanni
last_name: Biagioli
- first_name: Giulio
full_name: Mandorli, Giulio
last_name: Mandorli
- first_name: Lilli Johanna
full_name: Freischem, Lilli Johanna
last_name: Freischem
- first_name: Alejandro
full_name: Casallas Garcia, Alejandro
id: 92081129-2d75-11ef-a48d-b04dd7a2385a
last_name: Casallas Garcia
orcid: 0000-0002-1988-5035
- first_name: Adrian Mark
full_name: Tompkins, Adrian Mark
last_name: Tompkins
citation:
ama: 'Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. Spatial
patterns of shallow clouds: Challenging the concept of defined regimes. Geophysical
Research Letters. 2026;53(8). doi:10.1029/2025gl119921'
apa: 'Biagioli, G., Mandorli, G., Freischem, L. J., Casallas Garcia, A., & Tompkins,
A. M. (2026). Spatial patterns of shallow clouds: Challenging the concept of defined
regimes. Geophysical Research Letters. Wiley. https://doi.org/10.1029/2025gl119921'
chicago: 'Biagioli, Giovanni, Giulio Mandorli, Lilli Johanna Freischem, Alejandro
Casallas Garcia, and Adrian Mark Tompkins. “Spatial Patterns of Shallow Clouds:
Challenging the Concept of Defined Regimes.” Geophysical Research Letters.
Wiley, 2026. https://doi.org/10.1029/2025gl119921.'
ieee: 'G. Biagioli, G. Mandorli, L. J. Freischem, A. Casallas Garcia, and A. M.
Tompkins, “Spatial patterns of shallow clouds: Challenging the concept of defined
regimes,” Geophysical Research Letters, vol. 53, no. 8. Wiley, 2026.'
ista: 'Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. 2026.
Spatial patterns of shallow clouds: Challenging the concept of defined regimes.
Geophysical Research Letters. 53(8), e2025GL119921.'
mla: 'Biagioli, Giovanni, et al. “Spatial Patterns of Shallow Clouds: Challenging
the Concept of Defined Regimes.” Geophysical Research Letters, vol. 53,
no. 8, e2025GL119921, Wiley, 2026, doi:10.1029/2025gl119921.'
short: G. Biagioli, G. Mandorli, L.J. Freischem, A. Casallas Garcia, A.M. Tompkins,
Geophysical Research Letters 53 (2026).
date_created: 2026-04-21T06:04:41Z
date_published: 2026-04-28T00:00:00Z
date_updated: 2026-04-28T13:35:53Z
day: '28'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1029/2025gl119921
ec_funded: 1
file:
- access_level: open_access
checksum: 2cd4ae120b14b244f5b2f50eaae0efc1
content_type: application/pdf
creator: acasalla
date_created: 2026-04-21T06:07:22Z
date_updated: 2026-04-21T06:07:22Z
file_id: '21756'
file_name: Gio_Casallas_2026.pdf
file_size: 1544417
relation: main_file
success: 1
file_date_updated: 2026-04-21T06:07:22Z
has_accepted_license: '1'
intvolume: ' 53'
issue: '8'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Geophysical Research Letters
publication_identifier:
eissn:
- 1944-8007
issn:
- 0094-8276
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spatial patterns of shallow clouds: Challenging the concept of defined regimes'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21759'
abstract:
- lang: eng
text: 'Promoters and enhancers are cis-regulatory elements (CREs), DNA sequences
that bind transcription factor (TF) proteins to up- or down-regulate target genes.
Decades-long efforts yielded TF-DNA interaction models that predict how strongly
an individual TF binds arbitrary DNA sequences and how individual binding events
on the CRE combine to affect gene expression. These insights can be synthesized
into a global, biophysically realistic, and quantitative genotype-phenotype (GP)
map for gene regulation, a ‘holy grail’ for the application of evolutionary theory.
A global map provides a rare opportunity to simulate the long-term evolution of
regulatory sequences and pose several fundamental questions: How long does it
take to evolve CREs de novo? How many non-trivial regulatory functions exist in
sequence space? How connected are they? For which regulatory architecture is CRE
evolution most rapid and evolvable? In this article, the second of a two-part
series, we review the application of evolutionary concepts — epistasis, robustness,
evolvability, tunability, plasticity, and bet-hedging — to the evolution of gene
regulatory sequences. We then evaluate the potential for a unifying theory for
the evolution of regulatory sequences and identify key open challenges.'
acknowledgement: "We thank Calin Guet and Santiago Herrera-Álvarez for essential contributions
to this manuscript.\r\nE.M. acknowledges support from the APART-USA fellowship,
jointly funded by the Austrian Academy of Sciences (ÖAW) and the Institute of Science
and Technology Austria (ISTA). N.B. acknowledges funding from the ERC Advanced Grant
101055327 “HaplotypeStructure”.\r\nThis study was also supported by the European
Molecular Biology Laboratory (N.O.B., J.C.)."
article_number: '102472'
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Elia
full_name: Mascolo, Elia
id: 776a6ed0-a053-11f0-8635-80b95e0e0d53
last_name: Mascolo
orcid: 0000-0003-2977-7844
- first_name: Reka E
full_name: Körei, Reka E
id: 50FDE43E-AA30-11E9-A72B-8A12E6697425
last_name: Körei
- first_name: Noa O.
full_name: Borst, Noa O.
last_name: Borst
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Justin
full_name: Crocker, Justin
last_name: Crocker
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: 'Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. Long-term evolution
of regulatory DNA sequences. Part 2: Theory and future challenges. Current
Opinion in Genetics and Development. 2026;98. doi:10.1016/j.gde.2026.102472'
apa: 'Mascolo, E., Körei, R. E., Borst, N. O., Barton, N. H., Crocker, J., &
Tkačik, G. (2026). Long-term evolution of regulatory DNA sequences. Part 2: Theory
and future challenges. Current Opinion in Genetics and Development. Elsevier.
https://doi.org/10.1016/j.gde.2026.102472'
chicago: 'Mascolo, Elia, Reka E Körei, Noa O. Borst, Nicholas H Barton, Justin Crocker,
and Gašper Tkačik. “Long-Term Evolution of Regulatory DNA Sequences. Part 2: Theory
and Future Challenges.” Current Opinion in Genetics and Development. Elsevier,
2026. https://doi.org/10.1016/j.gde.2026.102472.'
ieee: 'E. Mascolo, R. E. Körei, N. O. Borst, N. H. Barton, J. Crocker, and G. Tkačik,
“Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges,”
Current Opinion in Genetics and Development, vol. 98. Elsevier, 2026.'
ista: 'Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. 2026. Long-term
evolution of regulatory DNA sequences. Part 2: Theory and future challenges. Current
Opinion in Genetics and Development. 98, 102472.'
mla: 'Mascolo, Elia, et al. “Long-Term Evolution of Regulatory DNA Sequences. Part
2: Theory and Future Challenges.” Current Opinion in Genetics and Development,
vol. 98, 102472, Elsevier, 2026, doi:10.1016/j.gde.2026.102472.'
short: E. Mascolo, R.E. Körei, N.O. Borst, N.H. Barton, J. Crocker, G. Tkačik, Current
Opinion in Genetics and Development 98 (2026).
corr_author: '1'
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-15T00:00:00Z
date_updated: 2026-06-18T08:34:09Z
day: '15'
ddc:
- '570'
department:
- _id: GaTk
- _id: NiBa
doi: 10.1016/j.gde.2026.102472
intvolume: ' 98'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.gde.2026.102472
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
grant_number: '101055327'
name: Understanding the evolution of continuous genomes
publication: Current Opinion in Genetics and Development
publication_identifier:
eissn:
- 1879-0380
issn:
- 0959-437X
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Long-term evolution of regulatory DNA sequences. Part 2: Theory and future
challenges'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 98
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21760'
abstract:
- lang: eng
text: 3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua
and 2I/Borisov. Its unusually high excess velocity and active cometary nature
make it a key probe of the Galactic population of icy planetesimals. Understanding
its origin requires its past trajectory through the Galaxy to be traced and the
possible role of stellar encounters to be assessed, both as a potential origin
and a perturber to its orbit. We integrated the orbit of 3I/ATLAS backward in
time for 10 Myr, together with a sample of Gaia DR3 stars with high-quality astrometry
and radial velocities, to identify close passages within 2 pc. We identify 93
nominal encounters, 62 of which are significant at the 2σ level. However, none
of these encounters produced any meaningful perturbation. The strongest perturber
Gaia DR3 6863591389529611264 at 0.30 pc and with a relative velocity of 35 km
s−1, imparted only a velocity change of ∣Δv∣ ≃ 5 × 10−4 km s−1 to the orbit
of 3I/ATLAS. Our results indicate that no stellar flybys within the past 10 Myr
and 500 pc contained in Gaia DR3 can account for the present trajectory of 3I/ATLAS
or be associated with its origin. We further show that 3I/ATLAS is kinematically
consistent with a thin-disk population, despite its large peculiar velocity.
acknowledgement: We thank the anonymous referee for a careful reading of the manuscript
and for constructive comments that improved the paper. X.P.C. and S.T. thank J.L.
Gragera-Más and Ylva Götberg for their valuable feedback and comments. X.P.C. acknowledges
financial support from the Spanish National Programme for the Promotion of Talent
and its Employability grant PRE2022-104959 cofunded by the European Social Fund.
S.T. acknowledges the funding from the European Union’s Horizon 2020 research and
innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413.
E.V. acknowledges support from the DISCOBOLO project funded by the Spanish Ministerio
de Ciencia, Innovación y Universidades under grant PID2021-127289NB-I00. A.J.M.
acknowledges support from the Swedish National Space Agency (Career grant 2023-00146).
X.P.C. and M.M. acknowledge support from the Spanish Ministerio de Ciencia, Innovaciòn
y Universidades under grants PID2021122842OB-C22 and PID2024-157964OB-C22; from
the Xunta de Galicia and the European Union (FEDER Galicia 2021-2027 Program) Ref.
ED431B 2024/21, ED431B 2024/02, and CITIC ED431G 2023/01. This work has made use
of data from the European Space Agency (ESA) Gaia mission and processed by the Gaia
Data Processing and Analysis Consortium (DPAC). Funding for the DPAC has been provided
by national institutions, particularly the institutions participating in the Gaia
Multilateral Agreement.
article_number: '146'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: X.
full_name: Pérez-Couto, X.
last_name: Pérez-Couto
- first_name: Santiago
full_name: Torres Rodriguez, Santiago
id: a8df4360-4328-11ee-8f1a-e502d0c83fc2
last_name: Torres Rodriguez
orcid: 0000-0002-3150-8988
- first_name: E.
full_name: Villaver, E.
last_name: Villaver
- first_name: A. J.
full_name: Mustill, A. J.
last_name: Mustill
- first_name: M.
full_name: Manteiga, M.
last_name: Manteiga
citation:
ama: 'Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 3I/ATLAS:
In search of the witnesses to its voyage. The Astrophysical Journal. 2026;1001(2).
doi:10.3847/1538-4357/ae56ff'
apa: 'Pérez-Couto, X., Torres Rodriguez, S., Villaver, E., Mustill, A. J., &
Manteiga, M. (2026). 3I/ATLAS: In search of the witnesses to its voyage. The
Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ae56ff'
chicago: 'Pérez-Couto, X., Santiago Torres Rodriguez, E. Villaver, A. J. Mustill,
and M. Manteiga. “3I/ATLAS: In Search of the Witnesses to Its Voyage.” The
Astrophysical Journal. IOP Publishing, 2026. https://doi.org/10.3847/1538-4357/ae56ff.'
ieee: 'X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A. J. Mustill, and M. Manteiga,
“3I/ATLAS: In search of the witnesses to its voyage,” The Astrophysical Journal,
vol. 1001, no. 2. IOP Publishing, 2026.'
ista: 'Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 2026.
3I/ATLAS: In search of the witnesses to its voyage. The Astrophysical Journal.
1001(2), 146.'
mla: 'Pérez-Couto, X., et al. “3I/ATLAS: In Search of the Witnesses to Its Voyage.”
The Astrophysical Journal, vol. 1001, no. 2, 146, IOP Publishing, 2026,
doi:10.3847/1538-4357/ae56ff.'
short: X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A.J. Mustill, M. Manteiga,
The Astrophysical Journal 1001 (2026).
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-04-28T13:08:39Z
day: '20'
ddc:
- '520'
department:
- _id: LiBu
doi: 10.3847/1538-4357/ae56ff
ec_funded: 1
external_id:
arxiv:
- '2509.07678'
file:
- access_level: open_access
checksum: c3daf49261a9933c079854c38eec316f
content_type: application/pdf
creator: dernst
date_created: 2026-04-28T13:06:00Z
date_updated: 2026-04-28T13:06:00Z
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file_size: 2905627
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- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: The Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: '3I/ATLAS: In search of the witnesses to its voyage'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1001
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21761'
abstract:
- lang: eng
text: Neural tube closure is a critical morphogenetic process in vertebrate development,
and failure to close cranial regions such as the hindbrain neuropore (HNP) leads
to severe congenital malformations. While mechanical forces such as actomyosin
purse-string contraction and directional cell crawling have been implicated in
driving HNP closure, how these forces organize local cell shape and motion to
produce large-scale tissue remodeling remains poorly understood. Using live and
fixed imaging of mouse embryos combined with cell-based biophysical modeling,
we show that these force-generating mechanisms are insufficient to explain the
reproducible patterns of cell elongation and nematic alignment observed at the
HNP border. Instead, we show that local anisotropic stress and cytoskeletal organization
are required to generate these patterns and promote midline cell motion. Our model
captures key features of cell shape dynamics and emergent nematic order, which
we confirm experimentally, including the alignment of actin fibers with cell shape
and enhanced midline cell speed. Comparative analysis with chick embryos, which
lack supracellular purse strings, supports a conserved link between tension generation
and cellular patterning. These findings establish a physical framework connecting
force generation, cell shape anisotropy, and tissue morphodynamics during epithelial
gap closure.
acknowledgement: S.B. acknowledges support from the National Institutes of Health
(NIH R35 GM143042) and the National Science Foundation (NSF MCB-2203601). G.L.G.
acknowledges support from the Wellcome Trust (211112/Z/18/Z), the Royal Society
(RG\R2\232082), and the Leverhulme Trust (RPG-2024-147). E.M. acknowledges support
from European Union’s Horizon 2021 Marie Sklodowska-Curie grant agreement no. 101067028.
F.P.-V. acknowledges support from the NOMIS foundation. The surface subtraction
macro is courtesy of Dr. Dale Moulding and available on GitHub (https://github.com/DaleMoulding/Fiji-Macros).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernanda L
full_name: Perez Verdugo, Fernanda L
id: 4ecec223-9070-11ef-a0a9-bc76077bea8d
last_name: Perez Verdugo
- first_name: Eirini
full_name: Maniou, Eirini
last_name: Maniou
- first_name: Gabriel L.
full_name: Galea, Gabriel L.
last_name: Galea
- first_name: Shiladitya
full_name: Banerjee, Shiladitya
last_name: Banerjee
citation:
ama: Perez Verdugo FL, Maniou E, Galea GL, Banerjee S. Mechanosensitive feedback
organizes cell shape and motion during hindbrain neuropore morphogenesis. Current
Biology. 2026;36(8):1903-1917.e5. doi:10.1016/j.cub.2026.02.068
apa: Perez Verdugo, F. L., Maniou, E., Galea, G. L., & Banerjee, S. (2026).
Mechanosensitive feedback organizes cell shape and motion during hindbrain neuropore
morphogenesis. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2026.02.068
chicago: Perez Verdugo, Fernanda L, Eirini Maniou, Gabriel L. Galea, and Shiladitya
Banerjee. “Mechanosensitive Feedback Organizes Cell Shape and Motion during Hindbrain
Neuropore Morphogenesis.” Current Biology. Elsevier, 2026. https://doi.org/10.1016/j.cub.2026.02.068.
ieee: F. L. Perez Verdugo, E. Maniou, G. L. Galea, and S. Banerjee, “Mechanosensitive
feedback organizes cell shape and motion during hindbrain neuropore morphogenesis,”
Current Biology, vol. 36, no. 8. Elsevier, p. 1903–1917.e5, 2026.
ista: Perez Verdugo FL, Maniou E, Galea GL, Banerjee S. 2026. Mechanosensitive feedback
organizes cell shape and motion during hindbrain neuropore morphogenesis. Current
Biology. 36(8), 1903–1917.e5.
mla: Perez Verdugo, Fernanda L., et al. “Mechanosensitive Feedback Organizes Cell
Shape and Motion during Hindbrain Neuropore Morphogenesis.” Current Biology,
vol. 36, no. 8, Elsevier, 2026, p. 1903–1917.e5, doi:10.1016/j.cub.2026.02.068.
short: F.L. Perez Verdugo, E. Maniou, G.L. Galea, S. Banerjee, Current Biology 36
(2026) 1903–1917.e5.
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-04-28T13:15:42Z
day: '20'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1016/j.cub.2026.02.068
external_id:
pmid:
- '41881011'
file:
- access_level: open_access
checksum: 80ae45457b4682c50c84f54de15aa9a8
content_type: application/pdf
creator: dernst
date_created: 2026-04-28T13:13:40Z
date_updated: 2026-04-28T13:13:40Z
file_id: '21774'
file_name: 2026_CurrentBiology_PerezVerdugo.pdf
file_size: 13402043
relation: main_file
success: 1
file_date_updated: 2026-04-28T13:13:40Z
has_accepted_license: '1'
intvolume: ' 36'
issue: '8'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1903-1917.e5
pmid: 1
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanosensitive feedback organizes cell shape and motion during hindbrain
neuropore morphogenesis
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2026'
...
---
OA_type: closed access
_id: '21762'
abstract:
- lang: eng
text: Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular
organization. The plasmid-encoded ParMRC system forms actin-like filaments that
segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena
sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal
system named CorMR with a function in cell shape control rather than DNA segregation.
Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed
that CorM formed dynamically unstable, antiparallel double-stranded filaments
that were recruited to the membrane by CorR through an amphipathic helix conserved
in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which
excluded them from the poles and division plane. Comparative genomics indicated
that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity,
highlighting the evolutionary plasticity of cytoskeletal systems in bacteria.
acknowledged_ssus:
- _id: Bio
- _id: ScienComp
- _id: EM-Fac
- _id: LifeSc
acknowledgement: "We thank all members of the Loose lab at ISTA for helpful discussions;
M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University)
for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial
strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial
strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing
the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix
screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data
collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work
was supported by the Scientific Service Units (SSU) of ISTA through resources provided
by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the
Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work
was funded by the European Union’s Horizon 2020 research and innovation program
(Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council
(ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National
Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques
et Letitia Lopez-Loreta Foundation (G.L.W.)."
article_number: eaea6343
article_processing_charge: No
article_type: original
author:
- first_name: Benjamin L
full_name: Springstein, Benjamin L
id: b4eb62ef-ac72-11ed-9503-ed3b4d66c083
last_name: Springstein
orcid: 0000-0002-3461-5391
- first_name: Manjunath
full_name: Javoor, Manjunath
id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
last_name: Javoor
orcid: 0000-0003-2311-2112
- first_name: Daniela
full_name: Megrian, Daniela
last_name: Megrian
- first_name: Roman
full_name: Hajdu, Roman
id: ffab949d-133f-11ed-8f02-94de21ace503
last_name: Hajdu
- first_name: Dustin M.
full_name: Hanke, Dustin M.
last_name: Hanke
- first_name: Bettina
full_name: Zens, Bettina
id: 45FD126C-F248-11E8-B48F-1D18A9856A87
last_name: Zens
orcid: 0000-0002-9561-1239
- first_name: Gregor L.
full_name: Weiss, Gregor L.
last_name: Weiss
- first_name: Florian Km
full_name: Schur, Florian Km
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Martin
full_name: Loose, Martin
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
citation:
ama: Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation
machinery into a cytoskeletal system controlling cell shape. Science. 2026;392(6795).
doi:10.1126/science.aea6343
apa: Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens,
B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal
system controlling cell shape. Science. AAAS. https://doi.org/10.1126/science.aea6343
chicago: Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu,
Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose.
“Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling
Cell Shape.” Science. AAAS, 2026. https://doi.org/10.1126/science.aea6343.
ieee: B. L. Springstein et al., “Repurposing of a DNA segregation machinery
into a cytoskeletal system controlling cell shape,” Science, vol. 392,
no. 6795. AAAS, 2026.
ista: Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL,
Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal
system controlling cell shape. Science. 392(6795), eaea6343.
mla: Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery
into a Cytoskeletal System Controlling Cell Shape.” Science, vol. 392,
no. 6795, eaea6343, AAAS, 2026, doi:10.1126/science.aea6343.
short: B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L.
Weiss, F.K. Schur, M. Loose, Science 392 (2026).
corr_author: '1'
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-04-28T13:29:05Z
day: '16'
department:
- _id: MaLo
- _id: FlSc
- _id: GradSch
- _id: EM-Fac
doi: 10.1126/science.aea6343
ec_funded: 1
external_id:
pmid:
- '41990175'
intvolume: ' 392'
issue: '6795'
language:
- iso: eng
month: '04'
oa_version: None
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
- _id: bd980d18-d553-11ed-ba76-ceaa645c97eb
grant_number: '101076260'
name: A molecular atlas of Actin filament IDentities in the cell motility machinery
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Repurposing of a DNA segregation machinery into a cytoskeletal system controlling
cell shape
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21763'
abstract:
- lang: eng
text: Reactive oxygen species (ROS) have been implicated in multiple signaling processes
in plants, but the underlying mechanisms and roles remain enigmatic. In this study,
we developed a method of live imaging of apoplastic ROS at the root surface. Distinct
signals, including auxin, extracellular adenosine triphosphate, and rapid alkalinization
factor 1 peptide, induce cytosolic calcium transients and apoplastic ROS bursts.
Genetic and optogenetic manipulations of Arabidopsis identified calcium transients
as necessary and sufficient for ROS bursts through activation of reduced nicotinamide
adenine dinucleotide phosphate (NADPH) oxidases RBOHC and RBOHF. Apoplastic ROS
bursts are not required, but they do limit gravity-induced root bending. Root
bending is sensed by the stretch-activated calcium channel MCA1, leading to NADPH
oxidase activation. The resulting ROS production stiffens cell walls to facilitate
soil penetration. Apoplastic ROS thus provides a means to balance tissue flexibility
and stiffness to navigate soil.
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: "We gratefully acknowledge the Lab Support Facility (LSF) and the
Imaging and Optics Facility (IOF) (both of ISTA) and the Hounsfield CT Facility
(University of Nottingham) for support with imaging and the Growth Facility (IPMB)
for plant cultivation. We thank M. Fendrych and his team for help with the microfluidics
upgrades and J. Atkinson at the University of Nottingham MakerSpace for 3D printing
of Arabidopsis mini-soil columns.\r\nThis project received funding from the European
Research Council (ERC; 101142681 CYNIPS) and the Austrian Science Fund (FWF; P 37051-B).
I.K. was cofunded by the European Union, Horizon Europe, project MOLIPEC, ID 101087030
and CSF project 25-16449S. L.V. and B.K.P. acknowledge funding from UK Research
and Innovation (UKRI) Frontiers Research (EP/Y036697/1). M.J.B. acknowledges funding
from ERC SYNERGY (grant 101118769 HYDROSENSING). The study was partially supported
by the Université Paris Cité, Idex ANR-18-IDEX-0001, funded by the French Government
through its “Investments for the Future” program and also by the projects “Mecha-Nuc”
ANR-20-CE13-0025-03 and “scEm-bryoMech” ANR-21-CE13-0046. P.D. acknowledges support
by Human Frontier Science Program Organization grant 2022-RG107. P.V. acknowledges
support provided by “Programme blanc” of the Graduate School BIOSPHERA, Université
Paris-Saclay. Phytohormonal analysis was performed using the service laboratory
funded by Toward Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of
the European Regional Development Fund (ERDF) program Johannes Amos Comenius. This
research was funded in whole or in part by the Austrian Science Fund (P 37051-B)
and UK Research and Innovation (EP/Y036697/1), cOAlition S organizations, and by
the European Research Council (101142681 CYNIPS, 101118769 HYDROSENSING); as required,
the author will make the Author Accepted Manuscript (AAM) version available under
a CC BY public copyright license."
article_processing_charge: No
article_type: original
author:
- first_name: Ivan
full_name: Kulich, Ivan
id: 57a1567c-8314-11eb-9063-c9ddc3451a54
last_name: Kulich
- first_name: Dmitrii
full_name: Vladimirtsev, Dmitrii
id: 60466724-5355-11ee-ae5a-fa55e8f99c3d
last_name: Vladimirtsev
- first_name: Marek
full_name: Randuch, Marek
id: 6ac4636d-15b2-11ec-abd3-fb8df79972ae
last_name: Randuch
- first_name: Shiqiang
full_name: Gao, Shiqiang
last_name: Gao
- first_name: Matteo
full_name: Citterico, Matteo
last_name: Citterico
- first_name: Kai R.
full_name: Konrad, Kai R.
last_name: Konrad
- first_name: Georg
full_name: Nagel, Georg
last_name: Nagel
- first_name: Michael
full_name: Wrzaczek, Michael
last_name: Wrzaczek
- first_name: Léa
full_name: Cascaro, Léa
last_name: Cascaro
- first_name: Pauline
full_name: Vinet, Pauline
last_name: Vinet
- first_name: Pauline
full_name: Durand, Pauline
last_name: Durand
- first_name: Atef
full_name: Asnacios, Atef
last_name: Asnacios
- first_name: Lokesh
full_name: Verma, Lokesh
last_name: Verma
- first_name: Malcolm J.
full_name: Bennett, Malcolm J.
last_name: Bennett
- first_name: Bipin K.
full_name: Pandey, Bipin K.
last_name: Pandey
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Kulich I, Vladimirtsev D, Randuch M, et al. Calcium-triggered apoplastic ROS
bursts balance gravity and mechanical signals for soil navigation. Science.
2026;392(6795):296-300. doi:10.1126/science.adu8197
apa: Kulich, I., Vladimirtsev, D., Randuch, M., Gao, S., Citterico, M., Konrad,
K. R., … Friml, J. (2026). Calcium-triggered apoplastic ROS bursts balance gravity
and mechanical signals for soil navigation. Science. AAAS. https://doi.org/10.1126/science.adu8197
chicago: Kulich, Ivan, Dmitrii Vladimirtsev, Marek Randuch, Shiqiang Gao, Matteo
Citterico, Kai R. Konrad, Georg Nagel, et al. “Calcium-Triggered Apoplastic ROS
Bursts Balance Gravity and Mechanical Signals for Soil Navigation.” Science.
AAAS, 2026. https://doi.org/10.1126/science.adu8197.
ieee: I. Kulich et al., “Calcium-triggered apoplastic ROS bursts balance
gravity and mechanical signals for soil navigation,” Science, vol. 392,
no. 6795. AAAS, pp. 296–300, 2026.
ista: Kulich I, Vladimirtsev D, Randuch M, Gao S, Citterico M, Konrad KR, Nagel
G, Wrzaczek M, Cascaro L, Vinet P, Durand P, Asnacios A, Verma L, Bennett MJ,
Pandey BK, Friml J. 2026. Calcium-triggered apoplastic ROS bursts balance gravity
and mechanical signals for soil navigation. Science. 392(6795), 296–300.
mla: Kulich, Ivan, et al. “Calcium-Triggered Apoplastic ROS Bursts Balance Gravity
and Mechanical Signals for Soil Navigation.” Science, vol. 392, no. 6795,
AAAS, 2026, pp. 296–300, doi:10.1126/science.adu8197.
short: I. Kulich, D. Vladimirtsev, M. Randuch, S. Gao, M. Citterico, K.R. Konrad,
G. Nagel, M. Wrzaczek, L. Cascaro, P. Vinet, P. Durand, A. Asnacios, L. Verma,
M.J. Bennett, B.K. Pandey, J. Friml, Science 392 (2026) 296–300.
corr_author: '1'
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-05-07T06:20:07Z
day: '16'
ddc:
- '580'
department:
- _id: JiFr
- _id: GradSch
doi: 10.1126/science.adu8197
external_id:
pmid:
- '41990180'
file:
- access_level: open_access
checksum: eb5b29247832ecdc53c8146da0509bbe
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T05:54:43Z
date_updated: 2026-05-07T05:54:43Z
file_id: '21832'
file_name: 2026_Science_Kulich_accepted.pdf
file_size: 6150733
relation: main_file
success: 1
file_date_updated: 2026-05-07T05:54:43Z
has_accepted_license: '1'
intvolume: ' 392'
issue: '6795'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Accepted Version
page: 296-300
pmid: 1
project:
- _id: 8f347782-16d5-11f0-9cad-8c19706ee739
grant_number: '101142681'
name: Cyclic nucleotides as second messengers in plants
- _id: 7bcece63-9f16-11ee-852c-ae94e099eeb6
grant_number: P37051
name: Guanylate cyclase activity of TIR1/AFBs auxin receptors
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Calcium-triggered apoplastic ROS bursts balance gravity and mechanical signals
for soil navigation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21764'
abstract:
- lang: eng
text: "Colloidal fluids can exhibit complex phase behavior and determining phase
diagrams via experiments or computer simulations can be laborious. We demonstrate
that the dispersion relation ω(k), obtained from dynamical density functional
theory for the uniform density system, is a highly versatile tool for predicting
where in the phase diagram complex crystals form. The sign of ω(k) determines
whether density modes with wave number k grow or decay over time. We demonstrate
the predictive power by investigating the complex phase behavior of particles
interacting via core-shoulder pair potentials. With complementary Monte Carlo
simulations, we show that regions of the phase diagram where ωðkÞ has one or several
unstable (growing) wave numbers are also where crystalline phases occur. Going
further, by tuning these\r\nunstable wave numbers via the interaction-potential
and state-point parameters, we design systems with quasicrystals in the phase
diagram. We identify a system with a certain shoulder range exhibiting at least
ten different phases. Our general approach accelerates considerably the mapping
of complex phase diagrams, crucial for the design of new materials."
acknowledgement: "The authors thank Ms. Katrin Muck for her guidance related to the
use of HPC. The MC\r\ncomputer simulation results presented here were enabled via
a generous share of CPU time, offered by the Vienna Scientific Cluster (VSC) under
Project No. 71263. A. J. A. gratefully acknowledges support from the EPSRC under
Grant No. EP/P015689/1. This research was funded in part by the Austrian Science
Fund (FWF) [Grant DOI: 10.55776/PIN8759524], gratefully acknowledged by G. K ."
article_number: '148203'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
full_name: Wassermair, Michael
id: 23d132c4-4e98-11ef-b275-9e8d4cd8c917
last_name: Wassermair
orcid: 0009-0003-6339-4051
- first_name: Gerhard
full_name: Kahl, Gerhard
last_name: Kahl
- first_name: Roland
full_name: Roth, Roland
last_name: Roth
- first_name: Andrew J.
full_name: Archer, Andrew J.
last_name: Archer
citation:
ama: Wassermair M, Kahl G, Roth R, Archer AJ. Navigating complex phase diagrams
in soft matter systems. Physical Review Letters. 2026;136(14). doi:10.1103/nbvt-fgjy
apa: Wassermair, M., Kahl, G., Roth, R., & Archer, A. J. (2026). Navigating
complex phase diagrams in soft matter systems. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/nbvt-fgjy
chicago: Wassermair, Michael, Gerhard Kahl, Roland Roth, and Andrew J. Archer. “Navigating
Complex Phase Diagrams in Soft Matter Systems.” Physical Review Letters.
American Physical Society, 2026. https://doi.org/10.1103/nbvt-fgjy.
ieee: M. Wassermair, G. Kahl, R. Roth, and A. J. Archer, “Navigating complex phase
diagrams in soft matter systems,” Physical Review Letters, vol. 136, no.
14. American Physical Society, 2026.
ista: Wassermair M, Kahl G, Roth R, Archer AJ. 2026. Navigating complex phase diagrams
in soft matter systems. Physical Review Letters. 136(14), 148203.
mla: Wassermair, Michael, et al. “Navigating Complex Phase Diagrams in Soft Matter
Systems.” Physical Review Letters, vol. 136, no. 14, 148203, American Physical
Society, 2026, doi:10.1103/nbvt-fgjy.
short: M. Wassermair, G. Kahl, R. Roth, A.J. Archer, Physical Review Letters 136
(2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-10T00:00:00Z
date_updated: 2026-04-28T07:03:48Z
day: '10'
ddc:
- '530'
department:
- _id: AnSa
- _id: GradSch
doi: 10.1103/nbvt-fgjy
external_id:
arxiv:
- '2603.18918'
file:
- access_level: open_access
checksum: 8ffb139122a185fcddbe6a9c901a287c
content_type: application/pdf
creator: dernst
date_created: 2026-04-28T06:58:40Z
date_updated: 2026-04-28T06:58:40Z
file_id: '21769'
file_name: 2026_PhysicalReviewLetters_Wassermair.pdf
file_size: 4336488
relation: main_file
success: 1
file_date_updated: 2026-04-28T06:58:40Z
has_accepted_license: '1'
intvolume: ' 136'
issue: '14'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Navigating complex phase diagrams in soft matter systems
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
OA_type: closed access
_id: '21765'
abstract:
- lang: eng
text: "Dielectric particles of the same material exchange electrical charge during
collisions or sliding contacts, yet the underlying charge-exchange mechanism is
still not understood. The fact that particles can become highly charged as a result
of this effect has significant consequences for many settings, both in nature
and industry, such as thunderstorms, volcanic eruptions, particle aggregation
during meteorite and planet formation, and the clogging of industrial granular
systems. Toward understanding these systems, great efforts have been made to develop
precise in situ measurements for particle charge, e.g., to determine ensemble
charge distributions or measure exchange during individual contacts. Here, we
present experimental results concerning the particle size scaling of the stationary-state
charge distributions of oxide particles in the sub-millimeter range. We measure
the charge distributions for large ensembles of monodisperse ZrO2:SiO2 composite
spheres, ranging from 172 to 545µm in diameter. These distributions are non-Gaussian
and collapse to a single master curve when plotted as functions of the surface
charge density Σ=\U0001D45E/4\U0001D70B\U0001D4452. X-ray fluorescence and atomic
force microscopy measurements show that the differences in the measured charge
distributions are not due to variations in chemical composition or surface roughness,
but rather to size alone. Our findings provide constraints on microscopic models
for charge exchange, namely that they should lead to steady-state distributions
that are non-Gaussian and scale in a specific way with particle size."
acknowledgement: This research was supported by ANID Grants QUIMAL No. 160001, FONDECYT
No. 1221597, and FONDEQUIP No. EQM190177. The authors thank Rodrigo Espinoza for
the EDS-SEM measurements and Domingo Jullian for fruitful discussions. We also acknowledge
the technical assistance of Ricardo Silva and Andrés Espinosa at DFI, FCFM, Universidad
de Chile.
article_number: '045604'
article_processing_charge: No
article_type: original
author:
- first_name: Macarena
full_name: Lara, Macarena
last_name: Lara
- first_name: Marcos
full_name: Flores, Marcos
last_name: Flores
- first_name: Gustavo
full_name: Castillo, Gustavo
last_name: Castillo
- first_name: Santiago
full_name: Tassara, Santiago
last_name: Tassara
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
- first_name: Nicolás
full_name: Mujica, Nicolás
last_name: Mujica
citation:
ama: Lara M, Flores M, Castillo G, Tassara S, Waitukaitis SR, Mujica N. Particle
size scaling of non-Gaussian granular charge distributions. Physical Review
Materials. 2026;10(4). doi:10.1103/qw6t-xqdw
apa: Lara, M., Flores, M., Castillo, G., Tassara, S., Waitukaitis, S. R., &
Mujica, N. (2026). Particle size scaling of non-Gaussian granular charge distributions.
Physical Review Materials. American Physical Society. https://doi.org/10.1103/qw6t-xqdw
chicago: Lara, Macarena, Marcos Flores, Gustavo Castillo, Santiago Tassara, Scott
R Waitukaitis, and Nicolás Mujica. “Particle Size Scaling of Non-Gaussian Granular
Charge Distributions.” Physical Review Materials. American Physical Society,
2026. https://doi.org/10.1103/qw6t-xqdw.
ieee: M. Lara, M. Flores, G. Castillo, S. Tassara, S. R. Waitukaitis, and N. Mujica,
“Particle size scaling of non-Gaussian granular charge distributions,” Physical
Review Materials, vol. 10, no. 4. American Physical Society, 2026.
ista: Lara M, Flores M, Castillo G, Tassara S, Waitukaitis SR, Mujica N. 2026. Particle
size scaling of non-Gaussian granular charge distributions. Physical Review Materials.
10(4), 045604.
mla: Lara, Macarena, et al. “Particle Size Scaling of Non-Gaussian Granular Charge
Distributions.” Physical Review Materials, vol. 10, no. 4, 045604, American
Physical Society, 2026, doi:10.1103/qw6t-xqdw.
short: M. Lara, M. Flores, G. Castillo, S. Tassara, S.R. Waitukaitis, N. Mujica,
Physical Review Materials 10 (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-04-28T07:13:56Z
day: '01'
department:
- _id: ScWa
doi: 10.1103/qw6t-xqdw
intvolume: ' 10'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
publication: Physical Review Materials
publication_identifier:
eissn:
- 2475-9953
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Particle size scaling of non-Gaussian granular charge distributions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21766'
abstract:
- lang: eng
text: We provide a new characterisation of the decades old open problem of extending
bilipschitz mappings given on a Euclidean separated net. In particular, this allows
for the complete positive solution of the open problem in dimension two. Along
the way, we develop a set of tools for bilipschitz extensions of mappings between
subsets of Euclidean spaces.
acknowledgement: "The present work developed from a research visit of M.D. to V.K.
at IST Austria, funded by\r\na London Mathematical Society Research in Pairs grant.
This work was done while V.K. was fully funded by the Austria Science Fund (FWF)
[M 3100-N]."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
full_name: Dymond, Michael
last_name: Dymond
- first_name: Vojtech
full_name: Kaluza, Vojtech
id: 21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E
last_name: Kaluza
orcid: 0000-0002-2512-8698
citation:
ama: Dymond M, Kaluza V. Extending bilipschitz mappings between separated nets.
Annales Fennici Mathematici. 2026;51(1):237-260. doi:10.54330/afm.181562
apa: Dymond, M., & Kaluza, V. (2026). Extending bilipschitz mappings between
separated nets. Annales Fennici Mathematici. Finnish Mathematical Society.
https://doi.org/10.54330/afm.181562
chicago: Dymond, Michael, and Vojtech Kaluza. “Extending Bilipschitz Mappings between
Separated Nets.” Annales Fennici Mathematici. Finnish Mathematical Society,
2026. https://doi.org/10.54330/afm.181562.
ieee: M. Dymond and V. Kaluza, “Extending bilipschitz mappings between separated
nets,” Annales Fennici Mathematici, vol. 51, no. 1. Finnish Mathematical
Society, pp. 237–260, 2026.
ista: Dymond M, Kaluza V. 2026. Extending bilipschitz mappings between separated
nets. Annales Fennici Mathematici. 51(1), 237–260.
mla: Dymond, Michael, and Vojtech Kaluza. “Extending Bilipschitz Mappings between
Separated Nets.” Annales Fennici Mathematici, vol. 51, no. 1, Finnish Mathematical
Society, 2026, pp. 237–60, doi:10.54330/afm.181562.
short: M. Dymond, V. Kaluza, Annales Fennici Mathematici 51 (2026) 237–260.
corr_author: '1'
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-17T00:00:00Z
date_updated: 2026-04-28T12:06:00Z
day: '17'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.54330/afm.181562
external_id:
arxiv:
- '2507.22007'
file:
- access_level: open_access
checksum: 442023926a3803d5d6ca8db8dbc4af1c
content_type: application/pdf
creator: dernst
date_created: 2026-04-28T12:03:13Z
date_updated: 2026-04-28T12:03:13Z
file_id: '21772'
file_name: 2026_AnnalesFenniciMath_Dymond.pdf
file_size: 342082
relation: main_file
success: 1
file_date_updated: 2026-04-28T12:03:13Z
has_accepted_license: '1'
intvolume: ' 51'
issue: '1'
keyword:
- Lipschitz
- bilipschitz
- extension
- separated net.
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 237-260
project:
- _id: fc35eaa2-9c52-11eb-aca3-88501ab155e9
grant_number: M03100
name: Spectra and topology of graphs and of simplicial complexes
publication: Annales Fennici Mathematici
publication_identifier:
eissn:
- 2737-114X
issn:
- 2737-0690
publication_status: published
publisher: Finnish Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extending bilipschitz mappings between separated nets
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 51
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21767'
abstract:
- lang: eng
text: 'The involvement of non-scientific staff in discussions about animal welfare
and scientific quality is essential for biomedical research progress. In this
study, we developed a survey to collect the self-perception of animal care staff
(ACS) and laboratory technicians about their involvement in scientific planning
and conduct. Participants were contacted to complete an anonymous online questionnaire.
We obtained 850 responses, mainly from Europe: 564 from ACS and 286 from laboratory
technicians. Job satisfaction was assessed as positive by ACS and laboratory technicians
despite the low frequency of culture of care activities and mental health meetings.
Both groups expressed their desire to be trained in research planning and conduct;
however, regular training was not reported. In addition, the inability to act
on animal welfare concerns owing to experimental reasons was reported by both
groups. Over half of the participants felt valued and appreciated by the lead
scientists or animal facility manager; however, it is not clear how they are acknowledged,
as their names on the authors list or in the manuscript acknowledgments are barely
included. Our results indicated that involvement of ACS and laboratory technicians
in planning and conducting studies would improve their understanding of how experiments
are done, and therefore communication processes, work satisfaction, animal welfare,
and scientific quality. Finally, we provided recommendations to improve the engagement
of ACS and laboratory technicians in discussions about animal research planning
and conduct.'
- lang: fre
text: 'La participation de personnel non-scientifique aux discussions sur le bien-être
animal et la qualité scientifique est essentielle aux progrès la recherche biomédicale.
Dans cette étude, nous avons développé une enquête pour recueillir l''auto-perception
du personnel chargé des soins prodigués aux animaux (PCSA) et des techniciens
de laboratoire (TL) sur leur implication dans la planification et la conduite
scientifiques. Les participants ont été contactés pour remplir un questionnaire
anonyme en ligne. Nous avons obtenu 850 réponses, principalement en Europe : 564
provenant de PCSA et 286 de TL. La satisfaction au travail a été évaluée comme
positive par le PCSA et les TL malgré la faible fréquence d’activités sur la culture
des soins et de réunions concernant la santé mentale. Bien que les deux groupes
aient exprimé leur désir d''être formés à la planification et à la conduite de
la recherche, aucune formation réelle régulière n''a été signalée. De plus, l''incapacité
d''agir sur les préoccupations relatives au bien-être animal pour des raisons
expérimentales a été signalée par les deux groupes. Plus de la moitié des participants
se sont sentis valorisés et appréciés par les scientifiques principaux ou le gestionnaire
de l’installation animale mais on ne sait pas clairement comment ils sont reconnus,
car leurs noms sur la liste des auteurs ou dans les remerciements sont à peine
inclus dans la documentation. Nos résultats ont indiqué que la participation du
PCSA et des TL à la planification et à la conduite des études améliorerait leur
compréhension de la façon dont les expériences sont effectuées et, par conséquent,
les processus de communication, leur satisfaction au travail ainsi que le bien-être
animal et la qualité scientifique. Enfin, nous avons formulé des recommandations
pour améliorer la participation du PCSA et des TL aux discussions sur la planification
et la conduite de la recherche animale.'
- lang: ger
text: 'Die Einbeziehung von nichtwissenschaftlichem Personal in Diskussionen über
Tierschutz und wissenschaftliche Qualität ist für Fortschritte in biomedizinischer
Forschung von entscheidender Bedeutung. In dieser Studie haben wir eine Umfrage
entwickelt, um die Selbsteinschätzung von Tierpflegern (ACS) und Labortechnikern
(LT) hinsichtlich ihrer Beteiligung an der wissenschaftlichen Planung und Durchführung
zu erfassen. Die Teilnehmer wurden gebeten, einen anonymen Online-Fragebogen auszufüllen.
Wir erhielten 850 Rückmeldungen, hauptsächlich aus Europa: 564 von ACS und 286
von LT. Die Arbeitszufriedenheit wurde von ACS und LT trotz der geringen Häufigkeit
von Pflegeaktivitäten und Treffen zum Thema psychische Gesundheit als positiv
bewertet. Beide Gruppen äußerten den Wunsch, in der Forschungsplanung und -durchführung
geschult zu werden, doch regelmäßig stattfindende Schulungen wurden nicht berichtet.
Außerdem wurde von beiden Gruppen vermeldet, dass sie aus versuchstechnischen
Gründen nicht in der Lage waren, auf Tierschutzbedenken zu reagieren. Über die
Hälfte der Teilnehmer fühlte sich von den leitenden Wissenschaftlern oder dem
Leiter der Tierhaltungseinrichtung geschätzt und anerkannt; es ist jedoch unklar,
inwiefern sie wirklich gewürdigt werden, da ihre Namen kaum in der Autorenliste
oder in den Danksagungen des Manuskripts aufgeführt sind. Unsere Ergebnisse deuteten
darauf hin, dass die Einbeziehung von ACS und LT in die Planung und Durchführung
von Studien ihr Verständnis für die Durchführung von Experimenten verbessern würde
– und damit auch Kommunikationsprozesse, Arbeitszufriedenheit, Tierwohl und wissenschaftliche
Qualität. Abschließend gaben wir Empfehlungen zur Verbesserung der Einbeziehung
von ACS und LT in Diskussionen über die Planung und Durchführung von Tierversuchen.'
- lang: spa
text: 'La participación del personal no científico en los debates sobre el bienestar
animal y la calidad científica es fundamental para el avance de la investigación
biomédica. En este estudio, desarrollamos una encuesta para recoger la autopercepción
del personal encargado del cuidado de los animales (ACS) y de los técnicos de
laboratorio (LT) sobre su implicación en la planificación y la realización científicas.
Se contactó con los participantes para que cumplimentaran un cuestionario anónimo
en línea. Obtuvimos 850 respuestas, principalmente de Europa: 564 de ACS y 286
de LT. La satisfacción laboral fue evaluada como positiva por ACS y técnicos de
laboratorio a pesar de la baja frecuencia de actividades de cultura del cuidado
y reuniones sobre bienestar mental. Ambos grupos expresaron su deseo de recibir
formación en planificación y realización de investigaciones, sin embargo, no se
informó sobre una formación regular. Asimismo, ambos grupos señalaron la incapacidad
de actuar ante las preocupaciones sobre el bienestar animal por motivos experimentales.
Más de la mitad de los participantes se sintieron valorados y apreciados por los
científicos principales o el responsable de las instalaciones de animales; sin
embargo, no está claro cómo se les reconoce, ya que apenas se incluyen sus nombres
en la lista de autores o en los agradecimientos del manuscrito. Nuestros resultados
indicaron que la participación de los ACS y los LT en la planificación y realización
de los estudios mejoraría su comprensión de cómo se hacen los experimentos y,
por tanto, los procesos de comunicación, la satisfacción laboral, el bienestar
animal y la calidad científica. Finalmente, proporcionamos recomendaciones para
mejorar el compromiso de la AEC y la LT en los debates sobre la planificación
y la realización de investigaciones con animales.'
acknowledgement: "We deeply acknowledge all the animal care staff and laboratory technicians
who participated in this study! We acknowledge Working Groups 1 and 4 from COST
Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139,
supported by COST (European Cooperation in Science and Technology) for their feedback
and support. We also acknowledge Aoife Milford for her comments and contributions
to the final draft of the manuscript.\r\nThis publication was based on work from
the COST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”),
CA21139, supported by COST (European Cooperation in Science and Technology)."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernando
full_name: Gonzalez-Uarquin, Fernando
last_name: Gonzalez-Uarquin
- first_name: Paulin
full_name: Jirkof, Paulin
last_name: Jirkof
- first_name: Bettina
full_name: Bert, Bettina
last_name: Bert
- first_name: Penny
full_name: Hawkins, Penny
last_name: Hawkins
- first_name: Ljupco
full_name: Angelovski, Ljupco
last_name: Angelovski
- first_name: Jan
full_name: Baumgart, Jan
last_name: Baumgart
- first_name: Nadine
full_name: Baumgart, Nadine
last_name: Baumgart
- first_name: Özge S.
full_name: Cevik, Özge S.
last_name: Cevik
- first_name: Nuno H.
full_name: Franco, Nuno H.
last_name: Franco
- first_name: Erdal
full_name: Horata, Erdal
last_name: Horata
- first_name: Rohish
full_name: Kaura, Rohish
last_name: Kaura
- first_name: Winfried
full_name: Neuhaus, Winfried
last_name: Neuhaus
- first_name: Brigida
full_name: Riso, Brigida
last_name: Riso
- first_name: Adrian J.
full_name: Smith, Adrian J.
last_name: Smith
- first_name: Athanassia
full_name: Sotiropoulos, Athanassia
last_name: Sotiropoulos
- first_name: Augusto
full_name: Vitale, Augusto
last_name: Vitale
- first_name: Sophie
full_name: Schober, Sophie
id: 80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8
last_name: Schober
citation:
ama: 'Gonzalez-Uarquin F, Jirkof P, Bert B, et al. Building bridges: Involvement
of animal care staff and laboratory technicians in experimental planning and conduct
of animal studies for better job satisfaction and science. Laboratory Animals.
2026. doi:10.1177/00236772251400976'
apa: 'Gonzalez-Uarquin, F., Jirkof, P., Bert, B., Hawkins, P., Angelovski, L., Baumgart,
J., … Schober, S. (2026). Building bridges: Involvement of animal care staff and
laboratory technicians in experimental planning and conduct of animal studies
for better job satisfaction and science. Laboratory Animals. SAGE Publications.
https://doi.org/10.1177/00236772251400976'
chicago: 'Gonzalez-Uarquin, Fernando, Paulin Jirkof, Bettina Bert, Penny Hawkins,
Ljupco Angelovski, Jan Baumgart, Nadine Baumgart, et al. “Building Bridges: Involvement
of Animal Care Staff and Laboratory Technicians in Experimental Planning and Conduct
of Animal Studies for Better Job Satisfaction and Science.” Laboratory Animals.
SAGE Publications, 2026. https://doi.org/10.1177/00236772251400976.'
ieee: 'F. Gonzalez-Uarquin et al., “Building bridges: Involvement of animal
care staff and laboratory technicians in experimental planning and conduct of
animal studies for better job satisfaction and science,” Laboratory Animals.
SAGE Publications, 2026.'
ista: 'Gonzalez-Uarquin F, Jirkof P, Bert B, Hawkins P, Angelovski L, Baumgart J,
Baumgart N, Cevik ÖS, Franco NH, Horata E, Kaura R, Neuhaus W, Riso B, Smith AJ,
Sotiropoulos A, Vitale A, Schober S. 2026. Building bridges: Involvement of animal
care staff and laboratory technicians in experimental planning and conduct of
animal studies for better job satisfaction and science. Laboratory Animals.'
mla: 'Gonzalez-Uarquin, Fernando, et al. “Building Bridges: Involvement of Animal
Care Staff and Laboratory Technicians in Experimental Planning and Conduct of
Animal Studies for Better Job Satisfaction and Science.” Laboratory Animals,
SAGE Publications, 2026, doi:10.1177/00236772251400976.'
short: F. Gonzalez-Uarquin, P. Jirkof, B. Bert, P. Hawkins, L. Angelovski, J. Baumgart,
N. Baumgart, Ö.S. Cevik, N.H. Franco, E. Horata, R. Kaura, W. Neuhaus, B. Riso,
A.J. Smith, A. Sotiropoulos, A. Vitale, S. Schober, Laboratory Animals (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-14T00:00:00Z
date_updated: 2026-06-18T08:33:36Z
day: '14'
ddc:
- '570'
department:
- _id: PreCl
doi: 10.1177/00236772251400976
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1177/00236772251400976
month: '04'
oa: 1
oa_version: Published Version
publication: Laboratory Animals
publication_identifier:
eissn:
- 1758-1117
issn:
- 0023-6772
publication_status: epub_ahead
publisher: SAGE Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Building bridges: Involvement of animal care staff and laboratory technicians
in experimental planning and conduct of animal studies for better job satisfaction
and science'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21776'
abstract:
- lang: eng
text: Pyridyl motifs equipped with N-substituents can be powerful ligands for catalysis,
yet their broader adoption is limited by the lack of a practical method to prepare
these scaffolds. We report a modular, robust, and versatile Buchwald–Hartwig amination
protocol that enables the rapid synthesis of bipyridine, phenanthroline, terpyridine,
and pybox ligands bearing dialkylamine, diarylamine, and heteroaromatic N-substituents.
These conditions streamline ligand library synthesis and will facilitate systematic
studies in catalysis and related applications.
acknowledged_ssus:
- _id: LifeSc
- _id: MassSpec
- _id: NMR
- _id: M-Shop
acknowledgement: We gratefully acknowledge ISTA for generous financial support. B.P.
acknowledges the Austrian Science Fund (PAT 1250924) and the ACS GCI Pharmaceutical
Roundtable for funding; T.P.Y acknowledges the NSF(CHE-2349003) for financial support.
This research was supported by the Scientific Service Units (SSU) of ISTA through
resources provided by the Lab Support Facility, Mass Spec Facility, NMR facility,
and the Miba Machine Shop. We specifically thank Aikaterina Paraskevopoulou for
HRMS measurements and Jan Pecak for support with ICP-OES experi-ments. NMR facilities
at UW−Madison were supported by the NSF(CHE-1048642) and a generous gift from Paul
J. and Margaret M. Bender. Open Access funding provided by Institute of Science
and Technology Austria/KEMÖ. This study was supported by Austrian Science Fund (PAT
1250924), ACSGCI Pharmaceutical Roundtable, and National Science Foundation(CHE-2349003)
and (CHE-1048642).
article_number: e70417
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Adam
full_name: Petrik, Adam
id: e273d403-329f-11ee-a353-8c34c056f8ed
last_name: Petrik
- first_name: Aleksander
full_name: Bena, Aleksander
id: 4197c39e-e8ec-11ed-86cb-afed934cd664
last_name: Bena
- first_name: Haralds
full_name: Baunis, Haralds
id: 2eea55ec-e8ec-11ed-86cb-d9c76787acfe
last_name: Baunis
- first_name: Riley M.
full_name: Kelch, Riley M.
last_name: Kelch
- first_name: Tehshik P.
full_name: Yoon, Tehshik P.
last_name: Yoon
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. Facile access to N-substituted
pyridyl ligands. Advanced Synthesis & Catalysis. 2026;368(9). doi:10.1002/adsc.70417
apa: Petrik, A., Bena, A., Baunis, H., Kelch, R. M., Yoon, T. P., & Pieber,
B. (2026). Facile access to N-substituted pyridyl ligands. Advanced Synthesis
& Catalysis. Wiley. https://doi.org/10.1002/adsc.70417
chicago: Petrik, Adam, Aleksander Bena, Haralds Baunis, Riley M. Kelch, Tehshik
P. Yoon, and Bartholomäus Pieber. “Facile Access to N-Substituted Pyridyl Ligands.”
Advanced Synthesis & Catalysis. Wiley, 2026. https://doi.org/10.1002/adsc.70417.
ieee: A. Petrik, A. Bena, H. Baunis, R. M. Kelch, T. P. Yoon, and B. Pieber, “Facile
access to N-substituted pyridyl ligands,” Advanced Synthesis & Catalysis,
vol. 368, no. 9. Wiley, 2026.
ista: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. 2026. Facile access
to N-substituted pyridyl ligands. Advanced Synthesis & Catalysis. 368(9),
e70417.
mla: Petrik, Adam, et al. “Facile Access to N-Substituted Pyridyl Ligands.” Advanced
Synthesis & Catalysis, vol. 368, no. 9, e70417, Wiley, 2026, doi:10.1002/adsc.70417.
short: A. Petrik, A. Bena, H. Baunis, R.M. Kelch, T.P. Yoon, B. Pieber, Advanced
Synthesis & Catalysis 368 (2026).
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-05-05T00:00:00Z
date_updated: 2026-05-07T07:33:33Z
day: '05'
ddc:
- '540'
department:
- _id: BaPi
- _id: GradSch
doi: 10.1002/adsc.70417
file:
- access_level: open_access
checksum: afe9752977898642c903abdc70b4a283
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T07:29:24Z
date_updated: 2026-05-07T07:29:24Z
file_id: '21833'
file_name: 2026_AdvSynthCatal_Petrik.pdf
file_size: 437184
relation: main_file
success: 1
file_date_updated: 2026-05-07T07:29:24Z
has_accepted_license: '1'
intvolume: ' 368'
issue: '9'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 8f1d607d-16d5-11f0-9cad-ab453295ba5e
grant_number: PAT 1250924
name: Photoactive ligands for transformative nickel catalysis
publication: Advanced Synthesis & Catalysis
publication_identifier:
eissn:
- 1615-4169
issn:
- 1615-4150
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Facile access to N-substituted pyridyl ligands
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 368
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21777'
abstract:
- lang: eng
text: The advantageous characteristics attributed to the 19F nucleus have made it
a popular target for nuclear magnetic resonance (NMR) once again in recent years.
Aside from solution NMR, an increasing number of studies have been conducted applying
solid-state magic-angle spinning (MAS) NMR to fluorine-labelled samples. Here,
the high chemical shift anisotropy and strong dipolar couplings can be utilised
to get structural insights into proteins and measure long distances. Despite increasing
popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR
often suffers from slow longitudinal T1 relaxation and therefore long recycle
delays. In this work, we expand paramagnetic doping, an approach commonly used
to reduce proton T1 relaxation times, to 19F-labelled biological samples. We study
the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F T1 and T2, and 13C T1 and T2 relaxation
in a [5-19F13C]-tryptophan-labelled protein via 19F-detected MAS NMR experiments.
The observed paramagnetic relaxation enhancement substantially reduces measurement
times of 19F MAS NMR experiments without compromising resolution. Additionally,
we report the chemical shift assignments of all four fluorotryptophan signals
in the 12×39 kDa-large protein TET2 using a mutagenesis approach.
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: We thank Ben P. Tatman for insightful discussions. This research
was supported by the Scientific Service Units (SSUs) of ISTA through resources provided
by the Nuclear Magnetic Resonance Facility and the Lab Support Facility. We thank
Prof. Tobias Madl (Medical University Graz) for a sample of Omniscan. Lea M. Becker
is the recipient of a DOC fellowship of the Austrian Academy of Sciences at the
Institute of Science and Technology Austria (grant no. PR10660EAW01).
article_processing_charge: Yes
article_type: original
author:
- first_name: Lea Marie
full_name: Becker, Lea Marie
id: 36336939-eb97-11eb-a6c2-c83f1214ca79
last_name: Becker
orcid: 0000-0002-6401-5151
- first_name: Giorgia
full_name: Toscano, Giorgia
id: 334a5e40-8747-11f0-b671-ba1f5154b4b4
last_name: Toscano
- first_name: Anna
full_name: Kapitonova, Anna
id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
last_name: Kapitonova
- first_name: Rajkumar
full_name: Singh, Rajkumar
id: a3089acd-6806-11ee-bacc-f0c7d500ad20
last_name: Singh
- first_name: Undina
full_name: Guillerm, Undina
id: bb74f472-ae54-11eb-9835-bc9c22fb1183
last_name: Guillerm
- first_name: Roman J.
full_name: Lichtenecker, Roman J.
last_name: Lichtenecker
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: Becker LM, Toscano G, Kapitonova A, et al. Accelerated 19F biomolecular magic-angle
spinning NMR with paramagnetic dopants. Magnetic Resonance. 2026;7(1):29-37.
doi:10.5194/mr-7-29-2026
apa: Becker, L. M., Toscano, G., Kapitonova, A., Singh, R., Guillerm, U., Lichtenecker,
R. J., & Schanda, P. (2026). Accelerated 19F biomolecular magic-angle spinning
NMR with paramagnetic dopants. Magnetic Resonance. Copernicus Publications.
https://doi.org/10.5194/mr-7-29-2026
chicago: Becker, Lea Marie, Giorgia Toscano, Anna Kapitonova, Rajkumar Singh, Undina
Guillerm, Roman J. Lichtenecker, and Paul Schanda. “Accelerated 19F Biomolecular
Magic-Angle Spinning NMR with Paramagnetic Dopants.” Magnetic Resonance.
Copernicus Publications, 2026. https://doi.org/10.5194/mr-7-29-2026.
ieee: L. M. Becker et al., “Accelerated 19F biomolecular magic-angle spinning
NMR with paramagnetic dopants,” Magnetic Resonance, vol. 7, no. 1. Copernicus
Publications, pp. 29–37, 2026.
ista: Becker LM, Toscano G, Kapitonova A, Singh R, Guillerm U, Lichtenecker RJ,
Schanda P. 2026. Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic
dopants. Magnetic Resonance. 7(1), 29–37.
mla: Becker, Lea Marie, et al. “Accelerated 19F Biomolecular Magic-Angle Spinning
NMR with Paramagnetic Dopants.” Magnetic Resonance, vol. 7, no. 1, Copernicus
Publications, 2026, pp. 29–37, doi:10.5194/mr-7-29-2026.
short: L.M. Becker, G. Toscano, A. Kapitonova, R. Singh, U. Guillerm, R.J. Lichtenecker,
P. Schanda, Magnetic Resonance 7 (2026) 29–37.
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-05-07T06:49:59Z
day: '16'
ddc:
- '540'
department:
- _id: PaSc
- _id: GradSch
doi: 10.5194/mr-7-29-2026
external_id:
pmid:
- '42057802'
has_accepted_license: '1'
intvolume: ' 7'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5194/mr-7-29-2026
month: '04'
oa: 1
oa_version: Published Version
page: 29-37
pmid: 1
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
- _id: 7be609c4-9f16-11ee-852c-85015ce2b9b0
grant_number: '26777'
name: Exploring protein dynamics by solid-state MAS NMR through specific labeling
approaches
publication: Magnetic Resonance
publication_identifier:
eissn:
- 2699-0016
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...