[{"intvolume":"       995","file_date_updated":"2026-02-10T06:56:37Z","author":[{"first_name":"John David","last_name":"Silverman","full_name":"Silverman, John David"},{"first_name":"Junyao","last_name":"Li","full_name":"Li, Junyao"},{"first_name":"Xuheng","last_name":"Ding","full_name":"Ding, Xuheng"},{"last_name":"Onoue","full_name":"Onoue, Masafusa","first_name":"Masafusa"},{"first_name":"Michael A.","full_name":"Strauss, Michael A.","last_name":"Strauss"},{"full_name":"Matsuoka, Yoshiki","last_name":"Matsuoka","first_name":"Yoshiki"},{"first_name":"Takuma","last_name":"Izumi","full_name":"Izumi, Takuma"},{"first_name":"Knud","full_name":"Jahnke, Knud","last_name":"Jahnke"},{"first_name":"Tommaso","last_name":"Treu","full_name":"Treu, Tommaso"},{"last_name":"Volonteri","full_name":"Volonteri, Marta","first_name":"Marta"},{"first_name":"Camryn L.","full_name":"Phillips, Camryn L.","last_name":"Phillips"},{"last_name":"Andika","full_name":"Andika, Irham T.","first_name":"Irham T."},{"last_name":"Aoki","full_name":"Aoki, Kentaro","first_name":"Kentaro"},{"last_name":"Arita","full_name":"Arita, Junya","first_name":"Junya"},{"last_name":"Baba","full_name":"Baba, Shunsuke","first_name":"Shunsuke"},{"last_name":"Bosman","full_name":"Bosman, Sarah E. I.","first_name":"Sarah E. I."},{"last_name":"Eilers","full_name":"Eilers, Anna-Christina","first_name":"Anna-Christina"},{"full_name":"Fan, Xiaohui","last_name":"Fan","first_name":"Xiaohui"},{"full_name":"Fujimoto, Seiji","last_name":"Fujimoto","first_name":"Seiji"},{"full_name":"Habouzit, Melanie","last_name":"Habouzit","first_name":"Melanie"},{"id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","full_name":"Haiman, Zoltán","last_name":"Haiman","orcid":"0000-0003-3633-5403"},{"first_name":"Masatoshi","last_name":"Imanishi","full_name":"Imanishi, Masatoshi"},{"full_name":"Inayoshi, Kohei","last_name":"Inayoshi","first_name":"Kohei"},{"first_name":"Kazushi","full_name":"Iwasawa, Kazushi","last_name":"Iwasawa"},{"full_name":"Kashikawa, Nobunari","last_name":"Kashikawa","first_name":"Nobunari"},{"first_name":"Toshihiro","full_name":"Kawaguchi, Toshihiro","last_name":"Kawaguchi"},{"last_name":"Lee","full_name":"Lee, Chien-Hsiu","first_name":"Chien-Hsiu"},{"last_name":"Lupi","full_name":"Lupi, Alessandro","first_name":"Alessandro"},{"first_name":"Tohru","last_name":"Nagao","full_name":"Nagao, Tohru"},{"first_name":"Jan-Torge","last_name":"Schindler","full_name":"Schindler, Jan-Torge"},{"first_name":"Malte","last_name":"Schramm","full_name":"Schramm, Malte"},{"first_name":"Kazuhiro","last_name":"Shimasaku","full_name":"Shimasaku, Kazuhiro"},{"full_name":"Toba, Yoshiki","last_name":"Toba","first_name":"Yoshiki"},{"last_name":"Trakhtenbrot","full_name":"Trakhtenbrot, Benny","first_name":"Benny"},{"full_name":"Umehata, Hideki","last_name":"Umehata","first_name":"Hideki"},{"first_name":"Marianne","last_name":"Vestergaard","full_name":"Vestergaard, Marianne"},{"full_name":"Walter, Fabian","last_name":"Walter","first_name":"Fabian"},{"first_name":"Feige","last_name":"Wang","full_name":"Wang, Feige"},{"full_name":"Yang, Jinyi","last_name":"Yang","first_name":"Jinyi"}],"publication":"The Astrophysical Journal Letters","oa":1,"publication_identifier":{"issn":["2041-8205"],"eissn":["2041-8213"]},"acknowledgement":"This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs GO #1967 and GO #3859. The specific observations analyzed can be accessed via DOI: 10.17909/719q-cn32. Support for these programs was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. This work was supported by World Premier International Research Center Initiative (WPI), MEXT, Japan. This work used computing resources at Kavli IPMU. J.S. is supported by JSPS KAKENHI (JP22H01262). M.O. is supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI grant No. 24K22894. Y.M. was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI grant No. 21H04494. M.V. gratefully acknowledges financial support from the Independent Research Fund Denmark via grant numbers DFF 8021-00130 and 3103-00146 and from the Carlsberg Foundation via grant CF23-0417. S.E.I.B. is supported by the Deutsche Forschungsgemeinschaft (DFG) under Emmy Noether grant number BO 5771/1-1. K.I. acknowledges support from the National Natural Science Foundation of China (12073003, 11721303, 11991052). K.I. acknowledges support under the grant PID2022-136827NB-C44 provided by MCIN/AEI/10.13039/501100011033 / FEDER, UE. A.L. acknowledges support from PRIN MUR 2022— Project “2022935STW.” J.T.S. is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)—project number 518006966. F.W. acknowledges support from NSF award AST-2513040. M.H. acknowledges support from the FNS under the SNSF starting grant 218032. B.T. acknowledges support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement number 950533) and from the Excellence Cluster ORIGINS, which is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC 2094—390783311.","DOAJ_listed":"1","file":[{"success":1,"relation":"main_file","access_level":"open_access","file_size":997137,"file_id":"21202","date_created":"2026-02-10T06:56:37Z","file_name":"2025_AstrophysicalJounalLetters_Silvermann.pdf","creator":"dernst","date_updated":"2026-02-10T06:56:37Z","content_type":"application/pdf","checksum":"e38c0c444be9c1507eec28c62ce04cbc"}],"publication_status":"published","language":[{"iso":"eng"}],"department":[{"_id":"ZoHa"}],"external_id":{"arxiv":["2507.23066"]},"date_created":"2026-01-31T09:27:53Z","quality_controlled":"1","volume":995,"abstract":[{"lang":"eng","text":"The relation between the masses of supermassive black holes (SMBHs) and their host galaxies encodes information on their mode of growth, especially at the earliest epochs. The James Webb Space Telescope (JWST) has opened such investigations by detecting the host galaxies of active galactic nuclei (AGN) and more luminous quasars within the first billion years of the Universe (z ≳ 6). Here, we evaluate the relation between the mass of SMBHs and the total stellar mass of their host galaxies using a sample of nine quasars at 6.18 ≤ z ≤ 6.4 from the Subaru High-z Exploration of Low-luminosity Quasars survey with NIRCam and NIRSpec observations. We find that the observed location of these quasars in the SMBH–galaxy mass plane (logMBH/M 8–9; logM*/M 9.5–11) is consistent with a nonevolving intrinsic mass relation with dispersion (0.80 +0.23 -0.28 dex) higher than the local value (∼0.3–0.4 dex) of their more massive descendants. Our analysis is based on a forward model of systematics and includes a consideration of the impact of selection effects and measurement uncertainties with an assumption on the slope of the mass relation. While degeneracies between parameters persist, the best-fit solution has a reasonable AGN fraction (2.3%) of galaxies at z ∼ 6 with an actively growing UV-unobscured black hole. In particular, models with a substantially higher normalisation in MBH would require an unrealistically low intrinsic dispersion (∼0.22 dex). Consequently, our results predict a large population of AGN at lower black hole masses, as are now just starting to be discovered in focused efforts with JWST."}],"license":"https://creativecommons.org/licenses/by/4.0/","article_number":"L67","oa_version":"Published Version","year":"2025","date_updated":"2026-02-10T07:02:39Z","date_published":"2025-12-17T00:00:00Z","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","day":"17","type":"journal_article","publisher":"IOP Publishing","issue":"2","arxiv":1,"ddc":["520"],"doi":"10.3847/2041-8213/ae279c","OA_place":"publisher","article_type":"original","OA_type":"gold","title":"SHELLQs–JWST perspective on the intrinsic mass relation between supermassive black holes and their host galaxies at z > 6","month":"12","_id":"21121","citation":{"chicago":"Silverman, John David, Junyao Li, Xuheng Ding, Masafusa Onoue, Michael A. Strauss, Yoshiki Matsuoka, Takuma Izumi, et al. “SHELLQs–JWST Perspective on the Intrinsic Mass Relation between Supermassive Black Holes and Their Host Galaxies at z &#62; 6.” <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/2041-8213/ae279c\">https://doi.org/10.3847/2041-8213/ae279c</a>.","ista":"Silverman JD, Li J, Ding X, Onoue M, Strauss MA, Matsuoka Y, Izumi T, Jahnke K, Treu T, Volonteri M, Phillips CL, Andika IT, Aoki K, Arita J, Baba S, Bosman SEI, Eilers A-C, Fan X, Fujimoto S, Habouzit M, Haiman Z, Imanishi M, Inayoshi K, Iwasawa K, Kashikawa N, Kawaguchi T, Lee C-H, Lupi A, Nagao T, Schindler J-T, Schramm M, Shimasaku K, Toba Y, Trakhtenbrot B, Umehata H, Vestergaard M, Walter F, Wang F, Yang J. 2025. SHELLQs–JWST perspective on the intrinsic mass relation between supermassive black holes and their host galaxies at z &#62; 6. The Astrophysical Journal Letters. 995(2), L67.","ama":"Silverman JD, Li J, Ding X, et al. SHELLQs–JWST perspective on the intrinsic mass relation between supermassive black holes and their host galaxies at z &#62; 6. <i>The Astrophysical Journal Letters</i>. 2025;995(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/ae279c\">10.3847/2041-8213/ae279c</a>","apa":"Silverman, J. D., Li, J., Ding, X., Onoue, M., Strauss, M. A., Matsuoka, Y., … Yang, J. (2025). SHELLQs–JWST perspective on the intrinsic mass relation between supermassive black holes and their host galaxies at z &#62; 6. <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ae279c\">https://doi.org/10.3847/2041-8213/ae279c</a>","ieee":"J. D. Silverman <i>et al.</i>, “SHELLQs–JWST perspective on the intrinsic mass relation between supermassive black holes and their host galaxies at z &#62; 6,” <i>The Astrophysical Journal Letters</i>, vol. 995, no. 2. IOP Publishing, 2025.","short":"J.D. Silverman, J. Li, X. Ding, M. Onoue, M.A. Strauss, Y. Matsuoka, T. Izumi, K. Jahnke, T. Treu, M. Volonteri, C.L. Phillips, I.T. Andika, K. Aoki, J. Arita, S. Baba, S.E.I. Bosman, A.-C. Eilers, X. Fan, S. Fujimoto, M. Habouzit, Z. Haiman, M. Imanishi, K. Inayoshi, K. Iwasawa, N. Kashikawa, T. Kawaguchi, C.-H. Lee, A. Lupi, T. Nagao, J.-T. Schindler, M. Schramm, K. Shimasaku, Y. Toba, B. Trakhtenbrot, H. Umehata, M. Vestergaard, F. Walter, F. Wang, J. Yang, The Astrophysical Journal Letters 995 (2025).","mla":"Silverman, John David, et al. “SHELLQs–JWST Perspective on the Intrinsic Mass Relation between Supermassive Black Holes and Their Host Galaxies at z &#62; 6.” <i>The Astrophysical Journal Letters</i>, vol. 995, no. 2, L67, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/2041-8213/ae279c\">10.3847/2041-8213/ae279c</a>."},"PlanS_conform":"1","article_processing_charge":"Yes"},{"status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","day":"28","publisher":"IOP Publishing","issue":"1","has_accepted_license":"1","date_published":"2025-10-28T00:00:00Z","oa_version":"Published Version","year":"2025","date_updated":"2026-02-10T07:44:42Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"21124","title":"SHELLQs-JWST unveils the host galaxies of 12 quasars at z > 6","month":"10","article_processing_charge":"Yes","citation":{"apa":"Ding, X., Onoue, M., Silverman, J. D., Matsuoka, Y., Izumi, T., Strauss, M. A., … Yang, J. (2025). SHELLQs-JWST unveils the host galaxies of 12 quasars at z &#62; 6. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae045b\">https://doi.org/10.3847/1538-4357/ae045b</a>","ama":"Ding X, Onoue M, Silverman JD, et al. SHELLQs-JWST unveils the host galaxies of 12 quasars at z &#62; 6. <i>The Astrophysical Journal</i>. 2025;993(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae045b\">10.3847/1538-4357/ae045b</a>","ista":"Ding X, Onoue M, Silverman JD, Matsuoka Y, Izumi T, Strauss MA, Yang L, Jahnke K, Phillips CL, Treu T, Andika IT, Aoki K, Arita J, Baba S, Bosman SEI, Eilers A-C, Fujimoto S, Haiman Z, Imanishi M, Inayoshi K, Iwasawa K, Kartaltepe J, Kashikawa N, Kawaguchi T, Li J, Lee C-H, Lupi A, Schindler J-T, Schramm M, Shimasaku K, Shuntov M, Tanaka TS, Toba Y, Trakhtenbrot B, Umehata H, Vestergaard M, Wang F, Yang J. 2025. SHELLQs-JWST unveils the host galaxies of 12 quasars at z &#62; 6. The Astrophysical Journal. 993(1), 91.","chicago":"Ding, Xuheng, Masafusa Onoue, John D. Silverman, Yoshiki Matsuoka, Takuma Izumi, Michael A. Strauss, Lilan Yang, et al. “SHELLQs-JWST Unveils the Host Galaxies of 12 Quasars at z &#62; 6.” <i>The Astrophysical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-4357/ae045b\">https://doi.org/10.3847/1538-4357/ae045b</a>.","short":"X. Ding, M. Onoue, J.D. Silverman, Y. Matsuoka, T. Izumi, M.A. Strauss, L. Yang, K. Jahnke, C.L. Phillips, T. Treu, I.T. Andika, K. Aoki, J. Arita, S. Baba, S.E.I. Bosman, A.-C. Eilers, S. Fujimoto, Z. Haiman, M. Imanishi, K. Inayoshi, K. Iwasawa, J. Kartaltepe, N. Kashikawa, T. Kawaguchi, J. Li, C.-H. Lee, A. Lupi, J.-T. Schindler, M. Schramm, K. Shimasaku, M. Shuntov, T.S. Tanaka, Y. Toba, B. Trakhtenbrot, H. Umehata, M. Vestergaard, F. Wang, J. Yang, The Astrophysical Journal 993 (2025).","mla":"Ding, Xuheng, et al. “SHELLQs-JWST Unveils the Host Galaxies of 12 Quasars at z &#62; 6.” <i>The Astrophysical Journal</i>, vol. 993, no. 1, 91, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae045b\">10.3847/1538-4357/ae045b</a>.","ieee":"X. Ding <i>et al.</i>, “SHELLQs-JWST unveils the host galaxies of 12 quasars at z &#62; 6,” <i>The Astrophysical Journal</i>, vol. 993, no. 1. IOP Publishing, 2025."},"PlanS_conform":"1","arxiv":1,"ddc":["520"],"OA_place":"publisher","doi":"10.3847/1538-4357/ae045b","OA_type":"gold","article_type":"original","file":[{"file_id":"21206","date_created":"2026-02-10T07:42:21Z","creator":"dernst","file_name":"2025_AstrophysicalJournal_Ding.pdf","file_size":10064937,"content_type":"application/pdf","checksum":"36decd55832a270ce62086c1a279a254","date_updated":"2026-02-10T07:42:21Z","success":1,"relation":"main_file","access_level":"open_access"}],"acknowledgement":"We sincerely thank Xiaohui Fan and Shenli Tang for their valuable discussions and insightful suggestions.\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs GO #1967, GO #3859, and GO #1727. Support for these programs was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. This work was supported by the World Premier International Research Center Initiative (WPI), MEXT, Japan. This work used computing resources at Kavli IPMU. All the JWST data used in this paper can be found in MAST: doi:10.17909/hqaf-an74.\r\n\r\nSupport for this work was provided by NASA through grant JWST-GO-01727 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. X.D. is supported by Wuhan University's Double First-Class funding. M.O. is supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI grant No. G24K22894. Y.M. is supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI grant No. 21H04494. S.E.I.B. is supported by the Deutsche Forschungsgemeinschaft (DFG) under Emmy Noether grant No. B.O. 5771/1-1. J.S. is supported by JSPS KAKENHI (JP22H01262) and the World Premier International Research Center Initiative (WPI), MEXT, Japan. K.I. acknowledges support from the National Natural Science Foundation of China (12073003, 11721303, 11991052). A.L. acknowledges support from PRIN MUR 2022—Project “2022935STW” J.T.S. is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)—Project No. 518006966. M.V. gratefully acknowledges financial support from the Independent Research Fund Denmark via grant Nos. DFF 8021-00130 and 3103-00146. K.I. acknowledges support under grant PID2022-136827NB-C44 provided by MCIN/AEI/10.13039/501100011033/FEDER, UE. F.W. acknowledges support from NSF award AST-2513040.","DOAJ_listed":"1","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"oa":1,"publication":"The Astrophysical Journal","author":[{"first_name":"Xuheng","full_name":"Ding, Xuheng","last_name":"Ding"},{"full_name":"Onoue, Masafusa","last_name":"Onoue","first_name":"Masafusa"},{"first_name":"John D.","last_name":"Silverman","full_name":"Silverman, John D."},{"last_name":"Matsuoka","full_name":"Matsuoka, Yoshiki","first_name":"Yoshiki"},{"first_name":"Takuma","full_name":"Izumi, Takuma","last_name":"Izumi"},{"last_name":"Strauss","full_name":"Strauss, Michael A.","first_name":"Michael A."},{"first_name":"Lilan","full_name":"Yang, Lilan","last_name":"Yang"},{"full_name":"Jahnke, Knud","last_name":"Jahnke","first_name":"Knud"},{"last_name":"Phillips","full_name":"Phillips, Camryn L.","first_name":"Camryn L."},{"last_name":"Treu","full_name":"Treu, Tommaso","first_name":"Tommaso"},{"last_name":"Andika","full_name":"Andika, Irham T.","first_name":"Irham T."},{"first_name":"Kentaro","full_name":"Aoki, Kentaro","last_name":"Aoki"},{"first_name":"Junya","last_name":"Arita","full_name":"Arita, Junya"},{"full_name":"Baba, Shunsuke","last_name":"Baba","first_name":"Shunsuke"},{"full_name":"Bosman, Sarah E. I.","last_name":"Bosman","first_name":"Sarah E. I."},{"full_name":"Eilers, Anna-Christina","last_name":"Eilers","first_name":"Anna-Christina"},{"first_name":"Seiji","last_name":"Fujimoto","full_name":"Fujimoto, Seiji"},{"orcid":"0000-0003-3633-5403","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","last_name":"Haiman","full_name":"Haiman, Zoltán"},{"last_name":"Imanishi","full_name":"Imanishi, Masatoshi","first_name":"Masatoshi"},{"first_name":"Kohei","full_name":"Inayoshi, Kohei","last_name":"Inayoshi"},{"full_name":"Iwasawa, Kazushi","last_name":"Iwasawa","first_name":"Kazushi"},{"first_name":"Jeyhan","full_name":"Kartaltepe, Jeyhan","last_name":"Kartaltepe"},{"first_name":"Nobunari","last_name":"Kashikawa","full_name":"Kashikawa, Nobunari"},{"first_name":"Toshihiro","last_name":"Kawaguchi","full_name":"Kawaguchi, Toshihiro"},{"first_name":"Junyao","last_name":"Li","full_name":"Li, Junyao"},{"first_name":"Chien-Hsiu","full_name":"Lee, Chien-Hsiu","last_name":"Lee"},{"first_name":"Alessandro","full_name":"Lupi, Alessandro","last_name":"Lupi"},{"first_name":"Jan-Torge","last_name":"Schindler","full_name":"Schindler, Jan-Torge"},{"last_name":"Schramm","full_name":"Schramm, Malte","first_name":"Malte"},{"first_name":"Kazuhiro","last_name":"Shimasaku","full_name":"Shimasaku, Kazuhiro"},{"first_name":"Marko","full_name":"Shuntov, Marko","last_name":"Shuntov"},{"full_name":"Tanaka, Takumi S.","last_name":"Tanaka","first_name":"Takumi S."},{"last_name":"Toba","full_name":"Toba, Yoshiki","first_name":"Yoshiki"},{"last_name":"Trakhtenbrot","full_name":"Trakhtenbrot, Benny","first_name":"Benny"},{"full_name":"Umehata, Hideki","last_name":"Umehata","first_name":"Hideki"},{"first_name":"Marianne","last_name":"Vestergaard","full_name":"Vestergaard, Marianne"},{"first_name":"Feige","last_name":"Wang","full_name":"Wang, Feige"},{"first_name":"Jinyi","full_name":"Yang, Jinyi","last_name":"Yang"}],"file_date_updated":"2026-02-10T07:42:21Z","intvolume":"       993","volume":993,"quality_controlled":"1","abstract":[{"lang":"eng","text":"The advent of the James Webb Space Telescope (JWST) has opened new horizons in the study of quasar host galaxies during the reionization epoch (z > 6). Building upon our previous initial measurements of stellar light from two quasar host galaxies at these redshifts, we now report the detection of the stellar light from the full Cycle 1 sample of 12 distant moderate-luminosity quasar (M1450 > −24 mag) host galaxies at z > 6 from the Hyper Suprime-Cam Subaru Strategic Program. Using JWST/NIRCam observations at 1.5 and 3.6 μm combined with 2D image decomposition analysis, we successfully detect the host galaxies in 11 of the 12 targets, underscoring the high detection rates achievable with moderate-luminosity quasars. Based on two-band photometry and spectral energy distribution fitting, we find that our host galaxies are massive, with log M*/M⊙ = 9.5–11.0. The effective radii range from 0.6 to 3.2 kpc, comparable to the sizes of inactive galaxies with similar masses at z ∼ 6 as measured with imaging from COSMOS-Web. Intriguingly, the two quasar hosts with post-starburst features, which reside at the high-mass end of our sample and exhibit relatively compact morphologies, have similar size and stellar mass surface densities to quiescent galaxies at z ∼ 4–5. These findings suggest that the so-called galaxy compaction scenario is already in place at the reionization epoch, in which gas inflows during starburst phases drive centrally concentrated star formation followed by rapid quenching, bridging the structural transition of massive galaxies from relatively extended star-forming disks to compact quiescent systems."}],"article_number":"91","publication_status":"published","department":[{"_id":"ZoHa"}],"external_id":{"arxiv":["2505.03876"]},"date_created":"2026-01-31T09:29:11Z","language":[{"iso":"eng"}]},{"degree_awarded":"PhD","publication_status":"published","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"date_created":"2025-05-23T15:21:29Z","language":[{"iso":"eng"}],"corr_author":"1","supervisor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","full_name":"Benková, Eva","last_name":"Benková","orcid":"0000-0002-8510-9739"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"file_date_updated":"2025-05-28T11:59:11Z","author":[{"id":"F8660870-D756-11E9-98C5-34DFE5697425","first_name":"Syamala","full_name":"Inumella, Syamala","last_name":"Inumella","orcid":"0009-0002-5890-120X"}],"acknowledgement":"Special thanks to the Plant Facility.","file":[{"embargo":"2026-05-23","access_level":"closed","relation":"main_file","embargo_to":"open_access","file_name":"Final Thesis_Syamala Inumella.pdf","creator":"sinumell","file_id":"19757","date_created":"2025-05-28T11:59:11Z","file_size":8292363,"content_type":"application/pdf","checksum":"847ec70b2e40f50e0ddc7b8da201d52c","date_updated":"2025-05-28T11:59:11Z"},{"relation":"source_file","access_level":"closed","date_updated":"2025-05-28T11:59:11Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","checksum":"17cdffdae13a5f65bdad9c84e9e0e3bd","file_size":7145703,"file_id":"19758","date_created":"2025-05-28T11:59:11Z","creator":"sinumell","file_name":"Final Thesis_Syamala Inumella.docx"}],"publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-059-6"]},"OA_embargo":"12","ddc":["580"],"doi":"10.15479/AT-ISTA-19722","OA_place":"publisher","alternative_title":["ISTA Thesis"],"_id":"19722","title":"Molecular mechanisms of microtubule reorganization in elongating root epidermal cells","month":"05","article_processing_charge":"No","citation":{"ieee":"S. Inumella, “Molecular mechanisms of microtubule reorganization in elongating root epidermal cells,” Institute of Science and Technology Austria, 2025.","mla":"Inumella, Syamala. <i>Molecular Mechanisms of Microtubule Reorganization in Elongating Root Epidermal Cells</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19722\">10.15479/AT-ISTA-19722</a>.","short":"S. Inumella, Molecular Mechanisms of Microtubule Reorganization in Elongating Root Epidermal Cells, Institute of Science and Technology Austria, 2025.","ista":"Inumella S. 2025. Molecular mechanisms of microtubule reorganization in elongating root epidermal cells. Institute of Science and Technology Austria.","chicago":"Inumella, Syamala. “Molecular Mechanisms of Microtubule Reorganization in Elongating Root Epidermal Cells.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-19722\">https://doi.org/10.15479/AT-ISTA-19722</a>.","apa":"Inumella, S. (2025). <i>Molecular mechanisms of microtubule reorganization in elongating root epidermal cells</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-19722\">https://doi.org/10.15479/AT-ISTA-19722</a>","ama":"Inumella S. Molecular mechanisms of microtubule reorganization in elongating root epidermal cells. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19722\">10.15479/AT-ISTA-19722</a>"},"date_published":"2025-05-23T00:00:00Z","has_accepted_license":"1","year":"2025","oa_version":"Published Version","date_updated":"2026-04-07T11:47:52Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"113","status":"public","day":"23","publisher":"Institute of Science and Technology Austria","type":"dissertation"},{"file_date_updated":"2025-12-17T09:46:34Z","author":[{"orcid":"0000-0002-5869-1604","full_name":"Wald, Sebastian","last_name":"Wald","id":"133F200A-B015-11E9-AD41-0EDAE5697425","first_name":"Sebastian"}],"keyword":["entanglement-enhanced atom interferometry","cavity QED","spin-squeezing","dipole trap","quantum optics"],"file":[{"file_size":47536855,"file_id":"20809","date_created":"2025-12-12T11:53:42Z","file_name":"2025_Wald_Sebastian_Thesis.pdf","creator":"swald","date_updated":"2025-12-17T09:46:34Z","content_type":"application/pdf","checksum":"1be72faf529a5e8a2d03cb3d5f808b77","embargo":"2026-06-15","embargo_to":"open_access","relation":"main_file","access_level":"closed"},{"file_id":"20810","date_created":"2025-12-12T11:54:55Z","file_name":"2025_Wald_Sebastian_Thesis.zip","creator":"swald","file_size":40127601,"content_type":"application/x-zip-compressed","checksum":"8c3a1904dceb4bcd04bc9f14b2594bab","date_updated":"2025-12-12T13:07:32Z","relation":"source_file","access_level":"closed"}],"publication_identifier":{"isbn":["978-3-99078-075-6"],"issn":["2663-337X"]},"OA_embargo":"6","degree_awarded":"PhD","publication_status":"published","date_created":"2025-12-11T11:48:11Z","department":[{"_id":"GradSch"},{"_id":"OnHo"}],"language":[{"iso":"eng"}],"corr_author":"1","supervisor":[{"last_name":"Hosten","full_name":"Hosten, Onur","first_name":"Onur","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2031-204X"}],"license":"https://creativecommons.org/licenses/by-nc/4.0/","has_accepted_license":"1","date_published":"2025-12-11T00:00:00Z","date_updated":"2026-04-07T12:35:11Z","year":"2025","oa_version":"Published Version","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"152","status":"public","tmp":{"short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png"},"day":"11","publisher":"Institute of Science and Technology Austria","type":"dissertation","ddc":["530"],"alternative_title":["ISTA Thesis"],"OA_place":"publisher","doi":"10.15479/AT-ISTA-20798","_id":"20798","month":"12","title":"Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry","article_processing_charge":"No","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"14759"}]},"citation":{"apa":"Wald, S. (2025). <i>Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20798\">https://doi.org/10.15479/AT-ISTA-20798</a>","ama":"Wald S. Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20798\">10.15479/AT-ISTA-20798</a>","ista":"Wald S. 2025. Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry. Institute of Science and Technology Austria.","chicago":"Wald, Sebastian. “Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom Interferometry.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20798\">https://doi.org/10.15479/AT-ISTA-20798</a>.","short":"S. Wald, Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom Interferometry, Institute of Science and Technology Austria, 2025.","mla":"Wald, Sebastian. <i>Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom Interferometry</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20798\">10.15479/AT-ISTA-20798</a>.","ieee":"S. Wald, “Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry,” Institute of Science and Technology Austria, 2025."}},{"language":[{"iso":"eng"}],"date_created":"2026-04-12T22:01:53Z","department":[{"_id":"JoMa"}],"publication_status":"published","article_number":"86","abstract":[{"text":"We present a comprehensive analysis of the MIRI Extremely Red Object Virgil, a Lyα emitter at zspec = 6.6379 ± 0.0035 with the photometric properties of a Little Red Dot. Leveraging new JWST/MIRI imaging from the MIDIS and PAHSPECS programs, we confirm Virgil’s extraordinary nature among galaxies in JADES/GOODS-South, exhibiting a strikingly red NIRCam-to-MIRI color (F444W–F1500W = 2.84 ± 0.04 mag). Deep NIRSpec/PRISM spectroscopy from the OASIS program offers key insights into the host galaxy, revealing properties of an average star-forming galaxy during Cosmic Reionization, such as a subsolar metallicity, low-to-moderate dust content, and a relatively high ionization parameter and electron temperature. By estimating the star formation rate of Virgil from UV and Hα, we find evidence that the galaxy is either entering or fading out of a bursty episode. Although line-ratio diagnostics employed at high z would classify Virgil as an active galactic nucleus (AGN), this classification becomes ambiguous once redshift evolution is considered. Nonetheless, Virgil occupies the same parameter space as recently confirmed AGNs at similar redshifts. The new deep MIRI data at 15 μm reinforce the AGN nature of Virgil, as inferred from multiple spectral energy distribution (SED) fitting codes. Virgil’s rising infrared SED and UV excess resemble those of Dust-Obscured Galaxies (DOGs) studied with Spitzer at Cosmic Noon, particularly blue-excess HotDOGs. Our results highlight the need for a multiwavelength approach incorporating MIRI to uncover such extreme sources at z ≳ 6 and to shed light on the interplay between galaxy evolution and early black hole growth during Cosmic Reionization.","lang":"eng"}],"quality_controlled":"1","volume":994,"intvolume":"       994","author":[{"last_name":"Rinaldi","full_name":"Rinaldi, Pierluigi","first_name":"Pierluigi"},{"first_name":"Pablo G.","last_name":"Pérez-González","full_name":"Pérez-González, Pablo G."},{"first_name":"George H.","last_name":"Rieke","full_name":"Rieke, George H."},{"last_name":"Lyu","full_name":"Lyu, Jianwei","first_name":"Jianwei"},{"full_name":"D’Eugenio, Francesco","last_name":"D’Eugenio","first_name":"Francesco"},{"first_name":"Zihao","full_name":"Wu, Zihao","last_name":"Wu"},{"last_name":"Carniani","full_name":"Carniani, Stefano","first_name":"Stefano"},{"full_name":"Looser, Tobias J.","last_name":"Looser","first_name":"Tobias J."},{"full_name":"Shivaei, Irene","last_name":"Shivaei","first_name":"Irene"},{"full_name":"Boogaard, Leindert A.","last_name":"Boogaard","first_name":"Leindert A."},{"first_name":"Tanio","full_name":"Diaz-Santos, Tanio","last_name":"Diaz-Santos"},{"first_name":"Luis","full_name":"Colina, Luis","last_name":"Colina"},{"last_name":"Östlin","full_name":"Östlin, Göran","first_name":"Göran"},{"last_name":"Alberts","full_name":"Alberts, Stacey","first_name":"Stacey"},{"last_name":"Álvarez-Márquez","full_name":"Álvarez-Márquez, Javier","first_name":"Javier"},{"first_name":"Marianna","full_name":"Annuziatella, Marianna","last_name":"Annuziatella"},{"first_name":"Manuel","full_name":"Aravena, Manuel","last_name":"Aravena"},{"first_name":"Rachana","full_name":"Bhatawdekar, Rachana","last_name":"Bhatawdekar"},{"first_name":"Andrew J.","last_name":"Bunker","full_name":"Bunker, Andrew J."},{"full_name":"Caputi, Karina I.","last_name":"Caputi","first_name":"Karina I."},{"last_name":"Charlot","full_name":"Charlot, Stéphane","first_name":"Stéphane"},{"last_name":"Crespo Gómez","full_name":"Crespo Gómez, Alejandro","first_name":"Alejandro"},{"first_name":"Mirko","last_name":"Curti","full_name":"Curti, Mirko"},{"first_name":"Andreas","last_name":"Eckart","full_name":"Eckart, Andreas"},{"last_name":"Gillman","full_name":"Gillman, Steven","first_name":"Steven"},{"first_name":"Kevin","full_name":"Hainline, Kevin","last_name":"Hainline"},{"last_name":"Kumari","full_name":"Kumari, Nimisha","first_name":"Nimisha"},{"last_name":"Hjorth","full_name":"Hjorth, Jens","first_name":"Jens"},{"first_name":"Edoardo","id":"4053390a-6b68-11ef-9828-a3b8adef8d0a","last_name":"Iani","full_name":"Iani, Edoardo","orcid":"0000-0001-8386-3546"},{"last_name":"Inami","full_name":"Inami, Hanae","first_name":"Hanae"},{"first_name":"Zhiyuan","full_name":"Ji, Zhiyuan","last_name":"Ji"},{"full_name":"Johnson, Benjamin D.","last_name":"Johnson","first_name":"Benjamin D."},{"first_name":"Gareth C.","last_name":"Jones","full_name":"Jones, Gareth C."},{"last_name":"Labiano","full_name":"Labiano, Álvaro","first_name":"Álvaro"},{"first_name":"Roberto","full_name":"Maiolino, Roberto","last_name":"Maiolino"},{"first_name":"Jens","full_name":"Melinder, Jens","last_name":"Melinder"},{"full_name":"Moutard, Thibaud","last_name":"Moutard","first_name":"Thibaud"},{"last_name":"Peissker","full_name":"Peissker, Florian","first_name":"Florian"},{"full_name":"Rieke, Marcia","last_name":"Rieke","first_name":"Marcia"},{"first_name":"Brant","full_name":"Robertson, Brant","last_name":"Robertson"},{"last_name":"Scholtz","full_name":"Scholtz, Jan","first_name":"Jan"},{"full_name":"Tacchella, Sandro","last_name":"Tacchella","first_name":"Sandro"},{"full_name":"Van Der Werf, Paul P.","last_name":"Van Der Werf","first_name":"Paul P."},{"last_name":"Walter","full_name":"Walter, Fabian","first_name":"Fabian"},{"last_name":"Williams","full_name":"Williams, Christina C.","first_name":"Christina C."},{"last_name":"Willott","full_name":"Willott, Chris","first_name":"Chris"},{"first_name":"Joris","last_name":"Witstok","full_name":"Witstok, Joris"},{"first_name":"Hannah","last_name":"Übler","full_name":"Übler, Hannah"},{"first_name":"Yongda","full_name":"Zhu, Yongda","last_name":"Zhu"}],"scopus_import":"1","file_date_updated":"2026-04-13T07:53:00Z","publication":"The Astrophysical Journal","oa":1,"publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"file":[{"date_updated":"2026-04-13T07:53:00Z","content_type":"application/pdf","checksum":"5d13b0ad3e9f56cbe29c5de0ba5757c8","file_size":10298729,"date_created":"2026-04-13T07:53:00Z","file_id":"21731","creator":"dernst","file_name":"2025_AstrophysicalJournal_Rinaldi.pdf","relation":"main_file","access_level":"open_access","success":1}],"DOAJ_listed":"1","acknowledgement":"The authors are deeply grateful to Antonello Calabrò for valuable insights on CLOUDY and pyCloudy, and for publicly sharing their SFG and AGN models, which were used as a reference to verify the consistency of our photoionization models. The authors also thank Adam Carnall for insightful input on bagpipes and for assistance with the implementation of the two-population model adopted in this work. Finally, they also thank Camilla Pacifici, Vasily Kokorev, and Cristian Vignali for their insightful discussions.\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with JWST programs GTO #1180, GO #1210, GTO#1283, GO #1963, GO #1895, GO# 3215, and GO#6511.\r\n\r\nThe authors acknowledge the FRESCO, JEMS, and #3215 teams led by co-PIs P. Oesch, C. C. Williams, M. Maseda, D. Eisenstein, and R. Maiolino for developing their observing program with a zero-exclusive-access period. Processing for the JADES NIRCam data release was performed on the lux cluster at the University of California, Santa Cruz, funded by NSF MRI grant AST 1828315. Also based on observations made with the NASA/ESA Hubble Space Telescope obtained from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 526555. The data presented in this article were obtained from MAST at the Space Telescope Science Institute. The specific observations analyzed can be accessed via doi: 10.17909/1rq3-8048 P. Oesch & D. Magee (2023), C. Williams et al. (2023), G. Illingworth (2015), and M. Rieke et al. (2023).\r\n\r\nA.J.B. acknowledges funding from the “FirstGalaxies” Advanced Grant from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No. 789056).\r\n\r\nP.G.P.-G. acknowledges support from grant PID2022-139567NB-I00 funded by the Spanish Ministerio de Ciencia e Innovación MCIN/AEI/10.13039/501100011033, FEDER, UE.\r\n\r\nB.E.R. acknowledges support from the NIRCam Science Team contract to the University of Arizona, NAS5-02015, and JWST Program 3215.\r\n\r\nS.T. acknowledges support by the Royal Society Research Grant G125142.\r\n\r\nThe research of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation.\r\n\r\nJ.W. gratefully acknowledges support from the Cosmic Dawn Center through the DAWN Fellowship. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant No. 140.\r\n\r\nY.Z., Z.J., and P.L. gratefully acknowledge the JWST/NIRCam contract to the University of Arizona NAS5-02015.\r\n\r\nThe work of G.H.R. and P.L. was also supported by grant 80NSSC18K0555, from the NASA Goddard Space Flight Center to the University of Arizona.\r\n\r\nH.Ü. acknowledges funding by the European Union (ERC APEX, 101164796). Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.\r\n\r\nG.C.J. acknowledges support by the Science and Technology Facilities Council (STFC), ERC Advanced grant 695671 “QUENCH.”\r\n\r\nA.C.G. acknowledges support by JWST contract B0215/JWST-GO-02926.\r\n\r\nG.O. acknowledges support from the Swedish National Space Agency (SNSA).\r\n\r\nH.I. acknowledges support from JSPS KAKENHI grant No. JP21H01129.\r\n\r\nM.A. gratefully acknowledges support from ANID Basal Project FB210003 and ANID MILENIO NCN2024_112.\r\n\r\nT.D.S. acknowledges the research project was supported by the Hellenic Foundation for Research and Innovation (HFRI) under the “2nd Call for HFRI Research Projects to Support Faculty Members and Researchers” (project No.: 03382).\r\n\r\nR.M. acknowledges support by the Science and Technology Facilities Council (STFC), by the ERC through Advanced grant 695671 “QUENCH,” and by the UKRI Frontier Research grant RISEandFALL. R.M. also acknowledges funding from a research professorship from the Royal Society.\r\n\r\nI.S. acknowledges funding from the Atraccíon de Talento grant No. 2022-T1/TIC-20472 of the Comunidad de Madrid, Spain, and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant No. 101117541, DistantDust).\r\n\r\nK.I.C. acknowledges funding from the Dutch Research Council (NWO) through the award of the Vici grant VI.C.212.036.\r\n\r\nFacilities: HST - Hubble Space Telescope satellite, JWST. -\r\n\r\nSoftware: Astropy (Astropy Collaboration et al. 2022), Bagpipes (A. C. Carnall et al. 2019), MSAEXP (G. Brammer 2023) NumPy (C. R. Harris et al. 2020), pandas (The pandas development team 2024) Photutils (L. Bradley et al. 2016), TOPCAT (M. Taylor 2022).","OA_type":"gold","article_type":"original","doi":"10.3847/1538-4357/ae089c","OA_place":"publisher","ddc":["520"],"PlanS_conform":"1","citation":{"mla":"Rinaldi, Pierluigi, et al. “Deciphering the Nature of Virgil: An Obscured Active Galactic Nucleus Lurking within an Apparently Normal Lyα Emitter during Cosmic Reionization.” <i>The Astrophysical Journal</i>, vol. 994, no. 1, 86, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae089c\">10.3847/1538-4357/ae089c</a>.","short":"P. Rinaldi, P.G. Pérez-González, G.H. Rieke, J. Lyu, F. D’Eugenio, Z. Wu, S. Carniani, T.J. Looser, I. Shivaei, L.A. Boogaard, T. Diaz-Santos, L. Colina, G. Östlin, S. Alberts, J. Álvarez-Márquez, M. Annuziatella, M. Aravena, R. Bhatawdekar, A.J. Bunker, K.I. Caputi, S. Charlot, A. Crespo Gómez, M. Curti, A. Eckart, S. Gillman, K. Hainline, N. Kumari, J. Hjorth, E. Iani, H. Inami, Z. Ji, B.D. Johnson, G.C. Jones, Á. Labiano, R. Maiolino, J. Melinder, T. Moutard, F. Peissker, M. Rieke, B. Robertson, J. Scholtz, S. Tacchella, P.P. Van Der Werf, F. Walter, C.C. Williams, C. Willott, J. Witstok, H. Übler, Y. Zhu, The Astrophysical Journal 994 (2025).","ieee":"P. Rinaldi <i>et al.</i>, “Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization,” <i>The Astrophysical Journal</i>, vol. 994, no. 1. IOP Publishing, 2025.","ama":"Rinaldi P, Pérez-González PG, Rieke GH, et al. Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization. <i>The Astrophysical Journal</i>. 2025;994(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae089c\">10.3847/1538-4357/ae089c</a>","apa":"Rinaldi, P., Pérez-González, P. G., Rieke, G. H., Lyu, J., D’Eugenio, F., Wu, Z., … Zhu, Y. (2025). Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae089c\">https://doi.org/10.3847/1538-4357/ae089c</a>","chicago":"Rinaldi, Pierluigi, Pablo G. Pérez-González, George H. Rieke, Jianwei Lyu, Francesco D’Eugenio, Zihao Wu, Stefano Carniani, et al. “Deciphering the Nature of Virgil: An Obscured Active Galactic Nucleus Lurking within an Apparently Normal Lyα Emitter during Cosmic Reionization.” <i>The Astrophysical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-4357/ae089c\">https://doi.org/10.3847/1538-4357/ae089c</a>.","ista":"Rinaldi P, Pérez-González PG, Rieke GH, Lyu J, D’Eugenio F, Wu Z, Carniani S, Looser TJ, Shivaei I, Boogaard LA, Diaz-Santos T, Colina L, Östlin G, Alberts S, Álvarez-Márquez J, Annuziatella M, Aravena M, Bhatawdekar R, Bunker AJ, Caputi KI, Charlot S, Crespo Gómez A, Curti M, Eckart A, Gillman S, Hainline K, Kumari N, Hjorth J, Iani E, Inami H, Ji Z, Johnson BD, Jones GC, Labiano Á, Maiolino R, Melinder J, Moutard T, Peissker F, Rieke M, Robertson B, Scholtz J, Tacchella S, Van Der Werf PP, Walter F, Williams CC, Willott C, Witstok J, Übler H, Zhu Y. 2025. Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization. The Astrophysical Journal. 994(1), 86."},"article_processing_charge":"Yes","month":"11","title":"Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization","_id":"21727","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-04-13T07:54:11Z","oa_version":"Published Version","year":"2025","date_published":"2025-11-20T00:00:00Z","has_accepted_license":"1","issue":"1","day":"20","type":"journal_article","publisher":"IOP Publishing","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public"},{"ddc":["530"],"doi":"10.1038/s41586-025-08786-6","OA_place":"publisher","article_type":"original","OA_type":"hybrid","title":"An integrated large-scale photonic accelerator with ultralow latency","month":"04","_id":"21549","citation":{"short":"S. Hua, E. Divita, S. Yu, B. Peng, C. Roques-Carmes, Z. Su, Z. Chen, Y. Bai, J. Zou, Y. Zhu, Y. Xu, C. Lu, Y. Di, H. Chen, L. Jiang, L. Wang, L. Ou, C. Zhang, J. Chen, W. Zhang, H. Zhu, W. Kuang, L. Wang, H. Meng, M. Steinman, Y. Shen, Nature 640 (2025) 361–367.","mla":"Hua, Shiyue, et al. “An Integrated Large-Scale Photonic Accelerator with Ultralow Latency.” <i>Nature</i>, vol. 640, Springer Nature, 2025, pp. 361–67, doi:<a href=\"https://doi.org/10.1038/s41586-025-08786-6\">10.1038/s41586-025-08786-6</a>.","ieee":"S. Hua <i>et al.</i>, “An integrated large-scale photonic accelerator with ultralow latency,” <i>Nature</i>, vol. 640. Springer Nature, pp. 361–367, 2025.","apa":"Hua, S., Divita, E., Yu, S., Peng, B., Roques-Carmes, C., Su, Z., … Shen, Y. (2025). An integrated large-scale photonic accelerator with ultralow latency. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-08786-6\">https://doi.org/10.1038/s41586-025-08786-6</a>","ama":"Hua S, Divita E, Yu S, et al. An integrated large-scale photonic accelerator with ultralow latency. <i>Nature</i>. 2025;640:361-367. doi:<a href=\"https://doi.org/10.1038/s41586-025-08786-6\">10.1038/s41586-025-08786-6</a>","ista":"Hua S, Divita E, Yu S, Peng B, Roques-Carmes C, Su Z, Chen Z, Bai Y, Zou J, Zhu Y, Xu Y, Lu C, Di Y, Chen H, Jiang L, Wang L, Ou L, Zhang C, Chen J, Zhang W, Zhu H, Kuang W, Wang L, Meng H, Steinman M, Shen Y. 2025. An integrated large-scale photonic accelerator with ultralow latency. Nature. 640, 361–367.","chicago":"Hua, Shiyue, Erwan Divita, Shanshan Yu, Bo Peng, Charles Roques-Carmes, Zhan Su, Zhang Chen, et al. “An Integrated Large-Scale Photonic Accelerator with Ultralow Latency.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-025-08786-6\">https://doi.org/10.1038/s41586-025-08786-6</a>."},"article_processing_charge":"No","oa_version":"Published Version","year":"2025","date_updated":"2026-04-27T08:38:44Z","date_published":"2025-04-09T00:00:00Z","extern":"1","page":"361-367","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"status":"public","type":"journal_article","day":"09","publisher":"Springer Nature","publication_status":"published","language":[{"iso":"eng"}],"external_id":{"pmid":[" 40205213"]},"date_created":"2026-03-30T12:22:47Z","quality_controlled":"1","volume":640,"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","abstract":[{"text":"Integrated photonics, particularly silicon photonics, have emerged as cutting-edge technology driven by promising applications such as short-reach communications, autonomous driving, biosensing and photonic computing1,2,3,4. As advances in AI lead to growing computing demands, photonic computing has gained considerable attention as an appealing candidate. Nonetheless, there are substantial technical challenges in the scaling up of integrated photonics systems to realize these advantages, such as ensuring consistent performance gains in upscaled integrated device clusters, establishing standard designs and verification processes for complex circuits, as well as packaging large-scale systems. These obstacles arise primarily because of the relative immaturity of integrated photonics manufacturing and the scarcity of advanced packaging solutions involving photonics. Here we report a large-scale integrated photonic accelerator comprising more than 16,000 photonic components. The accelerator is designed to deliver standard linear matrix multiply–accumulate (MAC) functions, enabling computing with high speed up to 1 GHz frequency and low latency as small as 3 ns per cycle. Logic, memory and control functions that support photonic matrix MAC operations were designed into a cointegrated electronics chip. To seamlessly integrate the electronics and photonics chips at the commercial scale, we have made use of an innovative 2.5D hybrid advanced packaging approach. Through the development of this accelerator system, we demonstrate an ultralow computation latency for heuristic solvers of computationally hard Ising problems whose performance greatly relies on the computing latency.","lang":"eng"}],"intvolume":"       640","author":[{"first_name":"Shiyue","full_name":"Hua, Shiyue","last_name":"Hua"},{"last_name":"Divita","full_name":"Divita, Erwan","first_name":"Erwan"},{"first_name":"Shanshan","full_name":"Yu, Shanshan","last_name":"Yu"},{"last_name":"Peng","full_name":"Peng, Bo","first_name":"Bo"},{"first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles","last_name":"Roques-Carmes"},{"full_name":"Su, Zhan","last_name":"Su","first_name":"Zhan"},{"first_name":"Zhang","last_name":"Chen","full_name":"Chen, Zhang"},{"first_name":"Yanfei","full_name":"Bai, Yanfei","last_name":"Bai"},{"first_name":"Jinghui","last_name":"Zou","full_name":"Zou, Jinghui"},{"full_name":"Zhu, Yunpeng","last_name":"Zhu","first_name":"Yunpeng"},{"last_name":"Xu","full_name":"Xu, Yelong","first_name":"Yelong"},{"last_name":"Lu","full_name":"Lu, Cheng-kuan","first_name":"Cheng-kuan"},{"first_name":"Yuemiao","full_name":"Di, Yuemiao","last_name":"Di"},{"last_name":"Chen","full_name":"Chen, Hui","first_name":"Hui"},{"first_name":"Lushan","last_name":"Jiang","full_name":"Jiang, Lushan"},{"last_name":"Wang","full_name":"Wang, Lijie","first_name":"Lijie"},{"first_name":"Longwu","full_name":"Ou, Longwu","last_name":"Ou"},{"first_name":"Chaohong","last_name":"Zhang","full_name":"Zhang, Chaohong"},{"first_name":"Junjie","last_name":"Chen","full_name":"Chen, Junjie"},{"first_name":"Wen","full_name":"Zhang, Wen","last_name":"Zhang"},{"last_name":"Zhu","full_name":"Zhu, Hongyan","first_name":"Hongyan"},{"first_name":"Weijun","last_name":"Kuang","full_name":"Kuang, Weijun"},{"full_name":"Wang, Long","last_name":"Wang","first_name":"Long"},{"first_name":"Huaiyu","last_name":"Meng","full_name":"Meng, Huaiyu"},{"first_name":"Maurice","last_name":"Steinman","full_name":"Steinman, Maurice"},{"full_name":"Shen, Yichen","last_name":"Shen","first_name":"Yichen"}],"scopus_import":"1","publication":"Nature","oa":1,"publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"pmid":1,"main_file_link":[{"url":"https://doi.org/10.1038/s41586-025-08786-6","open_access":"1"}]},{"file":[{"checksum":"c63dd47b0e77f9451821436bb77d27c9","content_type":"application/pdf","date_updated":"2025-11-24T08:25:19Z","date_created":"2025-11-24T08:25:19Z","file_id":"20672","creator":"dernst","file_name":"2025_MagneticResonance_Kapoor.pdf","file_size":3081399,"relation":"main_file","access_level":"open_access","success":1}],"acknowledgement":"First and foremost, we are grateful to the conference organizers who have provided data, either in the form of tables or by pointing us to abstract books. We thank the reviewers and the handling editor (Gottfried Otting) for the careful reading and suggestions. This project emerged from an interactive course about energy and climate, held at IST Austria by Jeroen Dobbelaere, Georgios Katsaros and Paul Schanda. We are grateful to ISTA's Graduate School for enabling this interdisciplinary course and to all participating students. We thank the following persons for discussions and/or comments about the manuscript: Helene Van Melckebeke, Mei Hong, Jeff Hoch, Gottfried Otting and Matthias Ernst. For the preparation of the manuscript, AI tools have been used, namely for finding relevant literature (ChatGPT) and for correcting the text (Writefull, within Overleaf LaTeX).","DOAJ_listed":"1","publication_identifier":{"eissn":["2699-0016"]},"oa":1,"author":[{"orcid":"0000-0001-8319-2148","full_name":"Kapoor, Lucky","last_name":"Kapoor","id":"84b9700b-15b2-11ec-abd3-831089e67615","first_name":"Lucky"},{"id":"D2761128-D73D-11E9-A1BF-BA0DE6697425","first_name":"Natalia","full_name":"Ruzickova, Natalia","last_name":"Ruzickova"},{"last_name":"Zivadinovic","full_name":"Zivadinovic, Predrag","id":"68AA0E5A-AFDA-11E9-9994-141DE6697425","first_name":"Predrag"},{"id":"4c665ce3-0016-11ec-bea0-e44de7a4fa3d","first_name":"Valentin","last_name":"Leitner","full_name":"Leitner, Valentin"},{"id":"44A03D04-AEA4-11E9-B225-EA2DE6697425","first_name":"Maria A","full_name":"Sisak, Maria A","last_name":"Sisak"},{"first_name":"Cecelia N","id":"2a69ab4b-896a-11ed-bdf8-cb8641cf2b21","last_name":"Mweka","full_name":"Mweka, Cecelia N"},{"last_name":"Dobbelaere","full_name":"Dobbelaere, Jeroen A","first_name":"Jeroen A","id":"c15a5412-de82-11ed-b809-8dc1aa996e40"},{"id":"38DB5788-F248-11E8-B48F-1D18A9856A87","first_name":"Georgios","last_name":"Katsaros","full_name":"Katsaros, Georgios","orcid":"0000-0001-8342-202X"},{"orcid":"0000-0002-9350-7606","first_name":"Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","last_name":"Schanda","full_name":"Schanda, Paul"}],"scopus_import":"1","file_date_updated":"2025-11-24T08:25:19Z","publication":"Magnetic Resonance","intvolume":"         6","volume":6,"quality_controlled":"1","abstract":[{"lang":"eng","text":"Conference travel contributes to the climate footprint of academic research. Here, we provide a quantitative estimate of the carbon emissions associated with conference attendance by analyzing travel data from participants of 10 international conferences in the field of magnetic resonance, namely EUROMAR, ENC and ICMRBS. We find that attending a EUROMAR conference produces, on average, more than 1 t CO2 eq.. For the analyzed conferences outside Europe, the corresponding value is about 2–3 times higher, on average, with intercontinental trips amounting to up to 5 t. We compare these conference-related emissions to other activities associated with research and show that conference travel is a substantial portion of the total climate footprint of a researcher in magnetic resonance. We explore several strategies to reduce these emissions, including the impact of selecting conference venues more strategically and the possibility of decentralized conferences. Through a detailed comparison of train versus air travel – accounting for both direct and infrastructure-related emissions – we demonstrate that train travel offers considerable carbon savings. These data may provide a basis for strategic choices of future conferences in the field and for individuals deciding on their conference attendance."}],"publication_status":"published","date_created":"2025-11-23T23:01:39Z","department":[{"_id":"JoFi"},{"_id":"GaTk"},{"_id":"JoCs"},{"_id":"EvBe"},{"_id":"TaHa"},{"_id":"GradSch"},{"_id":"GeKa"},{"_id":"PaSc"}],"corr_author":"1","language":[{"iso":"eng"}],"status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"issue":"2","type":"journal_article","day":"10","publisher":"Copernicus Publications","date_published":"2025-11-10T00:00:00Z","has_accepted_license":"1","date_updated":"2026-04-28T13:15:31Z","oa_version":"Published Version","year":"2025","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"243-256","_id":"20664","month":"11","title":"Quantifying the carbon footprint of conference travel: The case of NMR meetings","article_processing_charge":"Yes","PlanS_conform":"1","related_material":{"record":[{"status":"public","relation":"research_data","id":"20242"}],"link":[{"url":"https://ista.ac.at/en/news/carbon-footprint-of-conference-travel/","relation":"research_data","description":"News on ISTA website"}]},"citation":{"short":"L. Kapoor, N. Ruzickova, P. Zivadinovic, V. Leitner, M.A. Sisak, C.N. Mweka, J.A. Dobbelaere, G. Katsaros, P. Schanda, Magnetic Resonance 6 (2025) 243–256.","mla":"Kapoor, Lucky, et al. “Quantifying the Carbon Footprint of Conference Travel: The Case of NMR Meetings.” <i>Magnetic Resonance</i>, vol. 6, no. 2, Copernicus Publications, 2025, pp. 243–56, doi:<a href=\"https://doi.org/10.5194/mr-6-243-2025\">10.5194/mr-6-243-2025</a>.","ieee":"L. Kapoor <i>et al.</i>, “Quantifying the carbon footprint of conference travel: The case of NMR meetings,” <i>Magnetic Resonance</i>, vol. 6, no. 2. Copernicus Publications, pp. 243–256, 2025.","apa":"Kapoor, L., Ruzickova, N., Zivadinovic, P., Leitner, V., Sisak, M. A., Mweka, C. N., … Schanda, P. (2025). Quantifying the carbon footprint of conference travel: The case of NMR meetings. <i>Magnetic Resonance</i>. Copernicus Publications. <a href=\"https://doi.org/10.5194/mr-6-243-2025\">https://doi.org/10.5194/mr-6-243-2025</a>","ama":"Kapoor L, Ruzickova N, Zivadinovic P, et al. Quantifying the carbon footprint of conference travel: The case of NMR meetings. <i>Magnetic Resonance</i>. 2025;6(2):243-256. doi:<a href=\"https://doi.org/10.5194/mr-6-243-2025\">10.5194/mr-6-243-2025</a>","ista":"Kapoor L, Ruzickova N, Zivadinovic P, Leitner V, Sisak MA, Mweka CN, Dobbelaere JA, Katsaros G, Schanda P. 2025. Quantifying the carbon footprint of conference travel: The case of NMR meetings. Magnetic Resonance. 6(2), 243–256.","chicago":"Kapoor, Lucky, Natalia Ruzickova, Predrag Zivadinovic, Valentin Leitner, Maria A Sisak, Cecelia N Mweka, Jeroen A Dobbelaere, Georgios Katsaros, and Paul Schanda. “Quantifying the Carbon Footprint of Conference Travel: The Case of NMR Meetings.” <i>Magnetic Resonance</i>. Copernicus Publications, 2025. <a href=\"https://doi.org/10.5194/mr-6-243-2025\">https://doi.org/10.5194/mr-6-243-2025</a>."},"ddc":["000"],"article_type":"original","OA_type":"gold","OA_place":"publisher","doi":"10.5194/mr-6-243-2025"},{"_id":"20703","month":"12","title":"Less water from glaciers during future megadroughts in the Southern Andes","article_processing_charge":"Yes","related_material":{"link":[{"url":"https://ista.ac.at/en/news/the-future-fate-of-water-in-the-andes/","relation":"press_release","description":"News on ISTA website"}]},"PlanS_conform":"1","citation":{"ama":"Ayala Á, Muñoz-Castro E, Farinotti D, et al. Less water from glaciers during future megadroughts in the Southern Andes. <i>Communications Earth and Environment</i>. 2025;6. doi:<a href=\"https://doi.org/10.1038/s43247-025-02845-6\">10.1038/s43247-025-02845-6</a>","apa":"Ayala, Á., Muñoz-Castro, E., Farinotti, D., Farías-Barahona, D., Mendoza, P. A., Macdonell, S., … Pellicciotti, F. (2025). Less water from glaciers during future megadroughts in the Southern Andes. <i>Communications Earth and Environment</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s43247-025-02845-6\">https://doi.org/10.1038/s43247-025-02845-6</a>","chicago":"Ayala, Álvaro, Eduardo Muñoz-Castro, Daniel Farinotti, David Farías-Barahona, Pablo A. Mendoza, Shelley Macdonell, James Mcphee, Ximena Vargas, and Francesca Pellicciotti. “Less Water from Glaciers during Future Megadroughts in the Southern Andes.” <i>Communications Earth and Environment</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s43247-025-02845-6\">https://doi.org/10.1038/s43247-025-02845-6</a>.","ista":"Ayala Á, Muñoz-Castro E, Farinotti D, Farías-Barahona D, Mendoza PA, Macdonell S, Mcphee J, Vargas X, Pellicciotti F. 2025. Less water from glaciers during future megadroughts in the Southern Andes. Communications Earth and Environment. 6, 860.","short":"Á. Ayala, E. Muñoz-Castro, D. Farinotti, D. Farías-Barahona, P.A. Mendoza, S. Macdonell, J. Mcphee, X. Vargas, F. Pellicciotti, Communications Earth and Environment 6 (2025).","mla":"Ayala, Álvaro, et al. “Less Water from Glaciers during Future Megadroughts in the Southern Andes.” <i>Communications Earth and Environment</i>, vol. 6, 860, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s43247-025-02845-6\">10.1038/s43247-025-02845-6</a>.","ieee":"Á. Ayala <i>et al.</i>, “Less water from glaciers during future megadroughts in the Southern Andes,” <i>Communications Earth and Environment</i>, vol. 6. Springer Nature, 2025."},"ddc":["550"],"article_type":"original","OA_type":"gold","OA_place":"publisher","doi":"10.1038/s43247-025-02845-6","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"day":"01","type":"journal_article","publisher":"Springer Nature","date_published":"2025-12-01T00:00:00Z","project":[{"grant_number":"I06891","_id":"8e4c5b0b-16d5-11f0-9cad-9fa5f341393c","name":"Megadroughts in the Water towers of Europe - from process understanding to strategies for"},{"_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","name":"FWF Open Access Fund","call_identifier":"FWF"}],"has_accepted_license":"1","date_updated":"2026-04-28T13:16:58Z","oa_version":"Published Version","year":"2025","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","volume":6,"quality_controlled":"1","article_number":"860","abstract":[{"lang":"eng","text":"Glacier melt sustains water discharge from mountain basins during droughts, but ongoing glacier retreat threatens this fundamental capacity. Here, we assess the response of glaciers in the Southern Andes to one of the most severe, persistent, and extensive droughts on record in South America (2010-present), and to projected end-of-century megadroughts. Using glacio-hydrological numerical simulations, we show that despite a mean annual precipitation deficit of 36%, glacier runoff in 2010-2019 remained almost unaltered compared to the preceding decade (2000-2009), sustained by a 10% loss of total ice volume. However, simulations of future glacier evolution indicate that annual and summer glacier runoff could decline by up to 20 ± 11% and 48 ± 6%, respectively, during end-of-century megadroughts compared to pre-2010 levels. Our results project a weakening of the glacier’s buffering role against precipitation deficits during extreme droughts, increasing water scarcity for ecosystems and livelihoods in the mountain regions of South America."}],"publication_status":"published","date_created":"2025-11-30T23:02:06Z","external_id":{"isi":["001617609200003"]},"department":[{"_id":"FrPe"}],"language":[{"iso":"eng"}],"file":[{"access_level":"open_access","relation":"main_file","success":1,"content_type":"application/pdf","checksum":"1b23ad585d6f305447b54c606be0c46d","date_updated":"2025-12-01T09:10:13Z","creator":"dernst","file_name":"2025_CommEarthEnvir_Ayala.pdf","date_created":"2025-12-01T09:10:13Z","file_id":"20720","file_size":2468843}],"DOAJ_listed":"1","acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF), DOI: 10.55776/16891. The project MegaWat has received funding from the Austrian Science Fund (FWF), Swiss National Science Foundation (SNSF), the Centre for the Development of Industrial Technology (CDTI), Dutch Research Council (NWO), National Research Council (CNR) and the European Union’s Horizon Europe Programme under the 2022 Joint Transnational Call of the European Partnership Water4all (Grant Agreement n°101060874). Á.A. acknowledges Fondecyt Postdoc No. 3190732, the WSL programme ‘Extremes’ through the EMERGE project and together with S.M. ANID-CENTROS REGIONALES R20F0008. E.M.C. thanks ANID National Master scholarship year 2020 N°22200599 and the Swiss National Science Foundation Grant 200021_214907. P.A.M. acknowledges support from the Fondecyt project No. 11200142, and ANID/PIA project No AFB230001.","oa":1,"publication_identifier":{"eissn":["2662-4435"]},"scopus_import":"1","author":[{"first_name":"Álvaro","full_name":"Ayala, Álvaro","last_name":"Ayala"},{"last_name":"Muñoz-Castro","full_name":"Muñoz-Castro, Eduardo","first_name":"Eduardo"},{"last_name":"Farinotti","full_name":"Farinotti, Daniel","first_name":"Daniel"},{"last_name":"Farías-Barahona","full_name":"Farías-Barahona, David","first_name":"David"},{"full_name":"Mendoza, Pablo A.","last_name":"Mendoza","first_name":"Pablo A."},{"first_name":"Shelley","full_name":"Macdonell, Shelley","last_name":"Macdonell"},{"last_name":"Mcphee","full_name":"Mcphee, James","first_name":"James"},{"last_name":"Vargas","full_name":"Vargas, Ximena","first_name":"Ximena"},{"orcid":"0000-0002-5554-8087","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti"}],"file_date_updated":"2025-12-01T09:10:13Z","publication":"Communications Earth and Environment","intvolume":"         6","isi":1},{"corr_author":"1","language":[{"iso":"eng"}],"date_created":"2025-03-02T23:01:52Z","external_id":{"isi":["001428076100015"],"pmid":["39972227"]},"department":[{"_id":"ScWa"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"publication_status":"published","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"EM-Fac"},{"_id":"LifeSc"}],"article_number":"664-669","abstract":[{"lang":"eng","text":"When two insulating, neutral materials are contacted and separated, they exchange electrical charge1. Experiments have long suggested that this ‘contact electrification’ is transitive, with different materials ordering into ‘triboelectric series’ based on the sign of charge acquired2. At the same time, the effect is plagued by unpredictability, preventing consensus on the mechanism and casting doubt on the rhyme and reason that series imply3. Here we expose an unanticipated connection between the unpredictability and order in contact electrification: nominally identical materials initially exchange charge randomly and intransitively, but—over repeated experiments—order into triboelectric series. We find that this evolution is driven by the act of contact itself—samples with more contacts in their history charge negatively to ones with fewer contacts. Capturing this ‘contact bias’ in a minimal model, we recreate both the initial randomness and ultimate order in numerical simulations and use it experimentally to force the appearance of a triboelectric series of our choosing. With a set of surface-sensitive techniques to search for the underlying alterations contact creates, we only find evidence of nanoscale morphological changes, pointing to a mechanism strongly coupled with mechanics. Our results highlight the centrality of contact history in contact electrification and suggest that focusing on the unpredictability that has long plagued the effect may hold the key to understanding it."}],"quality_controlled":"1","volume":638,"isi":1,"intvolume":"       638","ec_funded":1,"file_date_updated":"2025-03-04T10:05:18Z","publication":"Nature","author":[{"last_name":"Sobarzo Ponce","full_name":"Sobarzo Ponce, Juan Carlos A","first_name":"Juan Carlos A","id":"4B807D68-AE37-11E9-AC72-31CAE5697425"},{"orcid":"0000-0003-0463-5794","last_name":"Pertl","full_name":"Pertl, Felix","id":"6313aec0-15b2-11ec-abd3-ed67d16139af","first_name":"Felix"},{"full_name":"Balazs, Daniel","last_name":"Balazs","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","first_name":"Daniel","orcid":"0000-0001-7597-043X"},{"orcid":"0000-0001-9732-3815","id":"D93824F4-D9BA-11E9-BB12-F207E6697425","first_name":"Tommaso","last_name":"Costanzo","full_name":"Costanzo, Tommaso"},{"last_name":"Sauer","full_name":"Sauer, Markus","first_name":"Markus"},{"last_name":"Foelske","full_name":"Foelske, Annette","first_name":"Annette"},{"first_name":"Markus","full_name":"Ostermann, Markus","last_name":"Ostermann"},{"first_name":"Christian M.","full_name":"Pichler, Christian M.","last_name":"Pichler"},{"last_name":"Wang","full_name":"Wang, Yongkang","first_name":"Yongkang"},{"first_name":"Yuki","last_name":"Nagata","full_name":"Nagata, Yuki"},{"full_name":"Bonn, Mischa","last_name":"Bonn","first_name":"Mischa"},{"orcid":"0000-0002-2299-3176","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","last_name":"Waitukaitis","full_name":"Waitukaitis, Scott R"}],"scopus_import":"1","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"oa":1,"pmid":1,"file":[{"date_updated":"2025-03-04T10:05:18Z","checksum":"fecf302274dd3218d3e7dd22f39a6c0c","content_type":"application/pdf","file_size":3807415,"creator":"dernst","file_name":"2025_Nature_Sobarzo.pdf","file_id":"19289","date_created":"2025-03-04T10:05:18Z","access_level":"open_access","relation":"main_file","success":1}],"acknowledgement":"This project has received financing from the European Research Council grant agreement no. 949120 under the European Union’s Horizon 2020 research and innovation programme. The Analytical Instrumentation Center of the TU Wien acknowledges support by the FFG project ‘ELSA’ under grant no. 884672. C.M.P. and M.O. acknowledge the state of Lower Austria and the European Regional Development Fund under grant no. WST3-F-542638/004-2021. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing facility, Electron Microscopy Facility and Lab Support Facility. We thank J. Garcia-Suarez and G. Anciaux for the suggestion to look into the roughness power spectral density. We thank I.-M. Strugaru for help with testing the device for Young’s modulus measurements. Open access funding provided by Institute of Science and Technology (IST Austria).","OA_type":"hybrid","article_type":"original","OA_place":"publisher","doi":"10.1038/s41586-024-08530-6","ddc":["530"],"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"20203"}],"link":[{"description":"News on ISTA website","relation":"press_release","url":"https://ista.ac.at/en/news/an-electrifying-turn-in-an-age-old-quest/"}]},"citation":{"ieee":"J. C. A. Sobarzo Ponce <i>et al.</i>, “Spontaneous ordering of identical materials into a triboelectric series,” <i>Nature</i>, vol. 638, no. 8051. Springer Nature, 2025.","short":"J.C.A. Sobarzo Ponce, F. Pertl, D. Balazs, T. Costanzo, M. Sauer, A. Foelske, M. Ostermann, C.M. Pichler, Y. Wang, Y. Nagata, M. Bonn, S.R. Waitukaitis, Nature 638 (2025).","mla":"Sobarzo Ponce, Juan Carlos A., et al. “Spontaneous Ordering of Identical Materials into a Triboelectric Series.” <i>Nature</i>, vol. 638, no. 8051, 664–669, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41586-024-08530-6\">10.1038/s41586-024-08530-6</a>.","ista":"Sobarzo Ponce JCA, Pertl F, Balazs D, Costanzo T, Sauer M, Foelske A, Ostermann M, Pichler CM, Wang Y, Nagata Y, Bonn M, Waitukaitis SR. 2025. Spontaneous ordering of identical materials into a triboelectric series. Nature. 638(8051), 664–669.","chicago":"Sobarzo Ponce, Juan Carlos A, Felix Pertl, Daniel Balazs, Tommaso Costanzo, Markus Sauer, Annette Foelske, Markus Ostermann, et al. “Spontaneous Ordering of Identical Materials into a Triboelectric Series.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-024-08530-6\">https://doi.org/10.1038/s41586-024-08530-6</a>.","apa":"Sobarzo Ponce, J. C. A., Pertl, F., Balazs, D., Costanzo, T., Sauer, M., Foelske, A., … Waitukaitis, S. R. (2025). Spontaneous ordering of identical materials into a triboelectric series. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-024-08530-6\">https://doi.org/10.1038/s41586-024-08530-6</a>","ama":"Sobarzo Ponce JCA, Pertl F, Balazs D, et al. Spontaneous ordering of identical materials into a triboelectric series. <i>Nature</i>. 2025;638(8051). doi:<a href=\"https://doi.org/10.1038/s41586-024-08530-6\">10.1038/s41586-024-08530-6</a>"},"article_processing_charge":"Yes (via OA deal)","month":"02","title":"Spontaneous ordering of identical materials into a triboelectric series","_id":"19278","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_updated":"2026-04-28T13:44:56Z","oa_version":"Published Version","year":"2025","date_published":"2025-02-20T00:00:00Z","project":[{"name":"Tribocharge: a multi-scale approach to an enduring problem in physics","call_identifier":"H2020","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","grant_number":"949120"}],"has_accepted_license":"1","issue":"8051","type":"journal_article","day":"20","publisher":"Springer Nature","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public"},{"language":[{"iso":"eng"}],"corr_author":"1","department":[{"_id":"GradSch"},{"_id":"ScWa"}],"date_created":"2025-08-21T11:42:59Z","publication_status":"published","degree_awarded":"PhD","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"ScienComp"}],"abstract":[{"text":"Tribocharging, or contact electrification, is the phenomenon in which two initially neutral materials exchange electric charge through contact and subsequent separation. While it is widely observed in everyday life and crucial to numerous natural processes, even the most basic aspects of tribocharging are still a mystery—what are the charge carriers involved and what drives their exchange? This work spans three separate projects that address different aspects of tribocharging. First, we introduce a novel strategy combining Finite Element Method (FEM) simulations with Kelvin Probe Force Microscopy (KPFM) to quantitatively extract surface charge density from surface voltage maps. Second, we present a simple theoretical model that allows for the existence of triboelectric cycles, under the assumption that multiple charge carrying species are involved. Third, we present experimental evidence that identical materials can spontaneously evolve into a triboelectric series, driven by contact history. Modeling this behavior enables the replication of experimental results with simulations, and even experimentally forcing the appearance of a pre-designed series by manipulating contact history. Together, the findings from these projects challenge traditional views on tribocharging, provide new tools for probing it, and open up new avenues of research—all with the hopes of bringing us closer to understanding this puzzling phenomenon.","lang":"eng"}],"supervisor":[{"last_name":"Waitukaitis","full_name":"Waitukaitis, Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","orcid":"0000-0002-2299-3176"}],"ec_funded":1,"author":[{"id":"4B807D68-AE37-11E9-AC72-31CAE5697425","first_name":"Juan Carlos A","full_name":"Sobarzo Ponce, Juan Carlos A","last_name":"Sobarzo Ponce"}],"file_date_updated":"2025-08-28T08:19:07Z","oa":1,"publication_identifier":{"isbn":["978-3-99078-062-6"],"issn":["2663-337X"]},"acknowledgement":"The project in Chapter 2 has received funding from the European Research Council (ERC) under\r\nthe European Union’s Horizon 2020 research and innovation programme (Grant Agreement\r\nNo. 949120).\r\nThe project in Chapter 3 has received funding from the European Research Council (ERC) under\r\nthe European Union’s Horizon 2020 research and innovation programme (Grant Agreement\r\nNo. 949120).\r\nThe project in Chapter 4 has received financing from the European Research Council grant\r\nagreement No. 949120 under the European Union’s Horizon 2020 research and innovation\r\nprogramme. The Analytical Instrumentation Center of the TU Wien acknowledges support by\r\nthe FFG project ‘ELSA’ under grant no. 884672. C.M.P. and M.O. acknowledge the state\r\nof Lower Austria and the European Regional Development Fund under grant no. WST3-F542638/004-2021.\r\n","file":[{"success":1,"relation":"main_file","access_level":"open_access","file_size":12667200,"date_created":"2025-08-27T14:50:32Z","file_id":"20237","creator":"jsobarzo","file_name":"2025_Sobarzo_JuanCarlos_Thesis.pdf","date_updated":"2025-08-27T14:50:32Z","content_type":"application/pdf","checksum":"661b9d3786cfc985be811befc3262bf5"},{"access_level":"closed","relation":"source_file","content_type":"application/x-zip-compressed","checksum":"ca2f24e6c3b55912982521707552a0f5","date_updated":"2025-08-28T08:19:07Z","creator":"jsobarzo","file_name":"2025_Sobarzo_JuanCarlos_Thesis.zip","date_created":"2025-08-27T14:50:32Z","file_id":"20238","file_size":18940521}],"OA_place":"publisher","doi":"10.15479/AT-ISTA-20203","alternative_title":["ISTA Thesis"],"ddc":["530"],"citation":{"apa":"Sobarzo Ponce, J. C. A. (2025). <i>Tribocharging of identical insulators : Triboelectric series, triboelectric cycles and surface charges</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20203\">https://doi.org/10.15479/AT-ISTA-20203</a>","ama":"Sobarzo Ponce JCA. Tribocharging of identical insulators : Triboelectric series, triboelectric cycles and surface charges. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20203\">10.15479/AT-ISTA-20203</a>","ista":"Sobarzo Ponce JCA. 2025. Tribocharging of identical insulators : Triboelectric series, triboelectric cycles and surface charges. Institute of Science and Technology Austria.","chicago":"Sobarzo Ponce, Juan Carlos A. “Tribocharging of Identical Insulators : Triboelectric Series, Triboelectric Cycles and Surface Charges.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20203\">https://doi.org/10.15479/AT-ISTA-20203</a>.","short":"J.C.A. Sobarzo Ponce, Tribocharging of Identical Insulators : Triboelectric Series, Triboelectric Cycles and Surface Charges, Institute of Science and Technology Austria, 2025.","mla":"Sobarzo Ponce, Juan Carlos A. <i>Tribocharging of Identical Insulators : Triboelectric Series, Triboelectric Cycles and Surface Charges</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20203\">10.15479/AT-ISTA-20203</a>.","ieee":"J. C. A. Sobarzo Ponce, “Tribocharging of identical insulators : Triboelectric series, triboelectric cycles and surface charges,” Institute of Science and Technology Austria, 2025."},"related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"12109"},{"id":"15322","status":"public","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"19278"}]},"article_processing_charge":"No","title":"Tribocharging of identical insulators : Triboelectric series, triboelectric cycles and surface charges","month":"08","_id":"20203","page":"96","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2025","oa_version":"Published Version","date_updated":"2026-04-28T13:44:56Z","has_accepted_license":"1","project":[{"_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","grant_number":"949120","name":"Tribocharge: a multi-scale approach to an enduring problem in physics","call_identifier":"H2020"}],"date_published":"2025-08-27T00:00:00Z","publisher":"Institute of Science and Technology Austria","day":"27","type":"dissertation","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public"},{"page":"268","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_updated":"2026-04-28T13:20:36Z","oa_version":"Published Version","year":"2025","project":[{"name":"Understanding the evolution of continuous genomes","grant_number":"101055327","_id":"bd6958e0-d553-11ed-ba76-86eba6a76c00"},{"name":"Snapdragon Speciation","grant_number":"P32166","_id":"05959E1C-7A3F-11EA-A408-12923DDC885E"}],"has_accepted_license":"1","date_published":"2025-11-25T00:00:00Z","type":"dissertation","publisher":"Institute of Science and Technology Austria","day":"25","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"status":"public","alternative_title":["ISTA Thesis"],"OA_place":"publisher","doi":"10.15479/AT-ISTA-20694","ddc":["576","578"],"related_material":{"record":[{"id":"12159","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","status":"public","id":"14796"},{"id":"20190","relation":"part_of_dissertation","status":"public"}]},"citation":{"chicago":"Pal, Arka. “Using Genealogies to Study the Genomic Basis of Species Divergence.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20694\">https://doi.org/10.15479/AT-ISTA-20694</a>.","ista":"Pal A. 2025. Using genealogies to study the genomic basis of species divergence. Institute of Science and Technology Austria.","ama":"Pal A. Using genealogies to study the genomic basis of species divergence. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20694\">10.15479/AT-ISTA-20694</a>","apa":"Pal, A. (2025). <i>Using genealogies to study the genomic basis of species divergence</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20694\">https://doi.org/10.15479/AT-ISTA-20694</a>","ieee":"A. Pal, “Using genealogies to study the genomic basis of species divergence,” Institute of Science and Technology Austria, 2025.","short":"A. Pal, Using Genealogies to Study the Genomic Basis of Species Divergence, Institute of Science and Technology Austria, 2025.","mla":"Pal, Arka. <i>Using Genealogies to Study the Genomic Basis of Species Divergence</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20694\">10.15479/AT-ISTA-20694</a>."},"article_processing_charge":"No","month":"11","title":"Using genealogies to study the genomic basis of species divergence","_id":"20694","file_date_updated":"2026-03-01T23:30:03Z","author":[{"first_name":"Arka","id":"6AAB2240-CA9A-11E9-9C1A-D9D1E5697425","last_name":"Pal","full_name":"Pal, Arka","orcid":"0000-0002-4530-8469"}],"oa":1,"publication_identifier":{"issn":["2663-337X"]},"file":[{"embargo":"2026-03-01","access_level":"open_access","relation":"main_file","file_size":42723135,"creator":"apal","file_name":"2025_Pal_Arka_Thesis.pdf","file_id":"20721","date_created":"2025-12-01T13:53:36Z","date_updated":"2026-03-01T23:30:03Z","content_type":"application/pdf","checksum":"7a10a738d58524aebb5dcbd9b34c21c5"},{"file_size":60632116,"file_name":"2025_Pal_Arka_Thesis.docx","creator":"apal","file_id":"20722","date_created":"2025-12-01T13:53:39Z","date_updated":"2026-03-01T23:30:03Z","checksum":"166d832b08d0434ce407f8f3cb930fe5","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","embargo_to":"open_access","access_level":"closed","relation":"source_file"}],"language":[{"iso":"eng"}],"corr_author":"1","date_created":"2025-11-25T13:19:11Z","department":[{"_id":"GradSch"},{"_id":"NiBa"}],"publication_status":"published","degree_awarded":"PhD","acknowledged_ssus":[{"_id":"ScienComp"}],"supervisor":[{"full_name":"Barton, Nicholas H","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","orcid":"0000-0002-8548-5240"}],"abstract":[{"text":"Understanding the mechanisms underlying speciation is a central aim of evolutionary biology.\r\nA persistent challenge in the field is to identify loci that contribute to reproductive isolation,\r\nwhile disentangling signals of selection from demography, linkage and intrinsic genomic\r\nfeatures. Traditional population genomic approaches that rely on site-based statistics in\r\narbitrary fixed windows face inherent limitations, as they conflate historical and\r\ncontemporary processes of divergence and overlook haplotype structure. Recent advances in\r\nwhole-genome sequencing and methods to infer ancestral recombination graphs (ARGs) now\r\noffer the opportunity to study genealogical relationships explicitly, revealing how lineages\r\ncoalesce and recombine through time. By directly analysing haplotype clustering by species\r\nor phenotype and their patterns of coalescence, ARG-based methods show promise for\r\ndiagnosing sweeps, identifying barrier loci maintained under divergent selection amid gene\r\nflow, and tracing their evolutionary history.\r\nIn this thesis, I explore the utility of genealogical approaches for studying species\r\ndivergence. In chapter 2, I propose a conceptual framework for defining haplotype blocks\r\nthrough the structure of the ARG, using simulations and empirical data to highlight how\r\ngenealogical processes generate rich and often overlooked haplotypic patterns.\r\nIn chapter 3, I examine the genomic basis of a key evolutionary innovation in marine\r\nsnails Littorina. These snails offer a unique opportunity to study an innovation because they\r\ninclude a very recent transition from egg-laying to live bearing, yet snails with the different\r\nreproductive modes are not reciprocally monophyletic. I exploited this by using topology\r\nclustering in ARG-derived local genealogical trees to pinpoint narrow genomic regions or\r\nhaplotype blocks that carry swept alleles, thus revealing that the transition from egg-laying\r\nto live-bearing involves multiple, live-bearer-specific sweeps.\r\nChapter 4 establishes a population-scale, phased genomic resource for Antirrhinum\r\nmajus, using cost-effective haplotagging, then optimizes imputation from low-coverage data\r\nagainst high-accuracy KASP sequencing to maximize sequence completeness with modest\r\naccuracy trade-offs against a traditional short-read sequence pipeline. A hybrid phasing\r\nstrategy combines molecular phasing with statistical phasing to generate phased whole\r\ngenome sequences of 1084 Antirrhinum individuals at a fraction of long-read sequencing\r\ncosts.\r\nIn chapter 5, I analyse hybridising populations from two replicate hybrid zones to find\r\na parallel genetic basis of flower colour, amidst the noise in genomic differentiation landscape\r\ndriven by variation in demographic history. While outlier genome scans of FST failed to dissect\r\nthe causes of differentiation, ARG-based topology clustering revealed a reuse of colour\r\nassociated haplotypes across hybrid zones. In addition to the biological insight, this chapter\r\nalso presents a comparison of the latest ARG inference tools, showing that signals of\r\nAbstract\r\nviii\r\ntopological clustering qualitatively agree between methods, despite differences in the tree\r\nsequences.\r\nNext, in chapter 6, by leveraging ~1000 individuals in one of the hybrid zones, I\r\nintegrated genome-wide association studies of floral pigmentation with genealogical\r\ninference, to test for additional colour loci, and confirm the effect of previously described loci.\r\nThis work demonstrates that flower colour variation is driven by a small number of large effect\r\nloci, while also hinting at the presence of a new candidate regulatory factor.\r\nFinally in chapter 7, in a preliminary analysis, I begin to dissect the genomic island of\r\nspeciation around Rosea/Eluta to understand its evolutionary origins. My results show that it\r\nconsists of 5 highly divergent loci, each of which is associated with flower colour. Using\r\npatterns of coalescence in genealogical trees, I find evidence of staggered selective sweeps\r\nand a persistent localized barrier to gene flow within an otherwise permeable genome.\r\nTogether, these chapters add to the increasing pool of studies using genealogical\r\napproaches to complement and extend site-based statistics to use haplotype structures in\r\nspeciation research. By tracking haplotypes directly and connecting genealogical clustering to\r\npopulation processes, ARG-based inference promises to provide new insights into how local\r\nselective pressures, demographic history, and long-term barriers interact to shape the\r\ngenomic architecture of divergence. By underscoring the value of ARGs in revealing the finescale origins and maintenance of biodiversity, this thesis presents cautious optimism about\r\nthe benefits of using genealogical inference to learn more than what site-based statistics\r\ncould tell us.","lang":"eng"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"109","date_published":"2025-04-01T00:00:00Z","has_accepted_license":"1","project":[{"_id":"237CBA6C-32DE-11EA-91FC-C7463DDC885E","grant_number":"862644","name":"Quantum readout techniques and technologies","call_identifier":"H2020"},{"_id":"bdb108fd-d553-11ed-ba76-83dc74a9864f","grant_number":"F07105","name":"QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration of Superconducting Quantum Circuits"}],"date_updated":"2026-04-16T12:20:42Z","oa_version":"Published Version","year":"2025","publisher":"Institute of Science and Technology Austria","day":"1","type":"dissertation","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"alternative_title":["ISTA Thesis"],"OA_place":"publisher","doi":"10.15479/AT-ISTA-19533","ddc":["530"],"article_processing_charge":"No","related_material":{"record":[{"status":"public","relation":"research_data","id":"18978"},{"relation":"part_of_dissertation","status":"public","id":"19280"},{"id":"13117","status":"public","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"17183"}]},"citation":{"chicago":"Sett, Riya. “ Quantum Remote Sensing and Non-Equilibrium Phase Transitions in the Microwave Regime.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-19533\">https://doi.org/10.15479/AT-ISTA-19533</a>.","ista":"Sett R. 2025.  Quantum remote sensing and non-equilibrium phase transitions in the microwave regime. Institute of Science and Technology Austria.","ama":"Sett R.  Quantum remote sensing and non-equilibrium phase transitions in the microwave regime. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19533\">10.15479/AT-ISTA-19533</a>","apa":"Sett, R. (2025). <i> Quantum remote sensing and non-equilibrium phase transitions in the microwave regime</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-19533\">https://doi.org/10.15479/AT-ISTA-19533</a>","ieee":"R. Sett, “ Quantum remote sensing and non-equilibrium phase transitions in the microwave regime,” Institute of Science and Technology Austria, 2025.","short":"R. Sett,  Quantum Remote Sensing and Non-Equilibrium Phase Transitions in the Microwave Regime, Institute of Science and Technology Austria, 2025.","mla":"Sett, Riya. <i> Quantum Remote Sensing and Non-Equilibrium Phase Transitions in the Microwave Regime</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19533\">10.15479/AT-ISTA-19533</a>."},"_id":"19533","month":"04","title":" Quantum remote sensing and non-equilibrium phase transitions in the microwave regime","file_date_updated":"2025-10-11T22:30:02Z","author":[{"full_name":"Sett, Riya","last_name":"Sett","id":"2E6D040E-F248-11E8-B48F-1D18A9856A87","first_name":"Riya","orcid":"0000-0001-7641-8348"}],"keyword":["phase transition","open quantum system","phase diagram","cavity quantum electrodynamics","superconducting qubits","semiclassical physics","quantum optics","josephson junction","parametric converter","phase conjugation","quantum radar","quantum entanglement","correlation","quantum sensing"],"ec_funded":1,"acknowledgement":"I acknowledge the generous financial support of the Austrian Science Fund (FWF) via BeyondC\r\n(F7105) and the European Union’s Horizon 2020 research and innovation program (FETopen\r\nQUARTET, Grant Agreement No. 862644), which made this research possible. I also extend\r\nmy sincere appreciation to the MIBA workshop and the Institute of Science and Technology\r\nAustria nanofabrication facility for their technical assistance, which was instrumental in realizing\r\nthis work.","file":[{"relation":"main_file","access_level":"open_access","embargo":"2025-10-11","date_updated":"2025-10-11T22:30:02Z","content_type":"application/pdf","checksum":"ba6cd2289d0141a160a14fc97df1632f","file_size":4129208,"date_created":"2025-04-10T11:33:22Z","file_id":"19538","creator":"rsett","file_name":"PhD_Thesis_Riya_Sett_pdfa.pdf"},{"embargo_to":"open_access","relation":"source_file","access_level":"closed","file_size":6646110,"date_created":"2025-04-10T11:34:08Z","file_id":"19539","creator":"rsett","file_name":"PhD Thesis Riya Sett.zip","date_updated":"2025-10-11T22:30:02Z","content_type":"application/x-zip-compressed","checksum":"ee63a94cb8f7adf5e766903028b81ed6"}],"publication_identifier":{"issn":["2663-337X"]},"oa":1,"date_created":"2025-04-09T16:44:26Z","department":[{"_id":"GradSch"},{"_id":"JoFi"}],"language":[{"iso":"eng"}],"corr_author":"1","degree_awarded":"PhD","publication_status":"published","supervisor":[{"orcid":"0000-0001-8112-028X","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87","first_name":"Johannes M","last_name":"Fink","full_name":"Fink, Johannes M"}],"abstract":[{"text":"This thesis explores advancements in quantum remote sensing and non-equilibrium phase\r\ntransitions in the microwave regime, with a focus on dissipative phase transitions and quantumenhanced sensing.\r\nIn the first project, I experimentally studied photon blockade breakdown as a dissipative phase\r\ntransition in a zero-dimensional cavity-qubit system. By defining an appropriate thermodynamic\r\nlimit, we demonstrated that the observed bistability is a genuine signature of a first-order\r\nphase transition in this system. This work provides insight into non-equilibrium quantum\r\ndynamics and phase transitions in driven-dissipative open quantum systems.\r\nThe second project focuses on the experimental realization of a phase-conjugate receiver for\r\nquantum illumination (QI), a quantum sensing protocol that enhances target detection in noisy\r\nenvironments using entangled light. While an ideal spontaneous parametric down-conversion\r\n(SPDC) source and receiver could, in theory, provide up to a 6 dB advantage over classical\r\nillumination, no such ideal receiver exists. Instead, we explore an experimental realization of a\r\nphase-conjugate receiver for QI in the microwave regime at millikelvin temperatures using a\r\nJosephson parametric converter (JPC) as a source of continuous-variable Gaussian entangled\r\nsignal-idler pairs, where a maximum 3 dB advantage is theoretically achievable. We investigate\r\nkey experimental limitations that constrain practical QI performance, contributing to the\r\ndevelopment of quantum-enhanced sensing.\r\nAdditionally, this thesis presents efficient digital signal processing (DSP) techniques implemented in C++ and Python in collaboration with Przemysław Zieliński and Luka Drmić. These\r\nmethods, optimized using the Intel Integrated Performance Primitives (IPP) library, have been\r\nessential in data acquisition, noise filtering, and correlation analysis across multiple research\r\nprojects. Although not real-time, these DSP techniques significantly enhance the accuracy of\r\nquantum measurements.\r\nOverall, this thesis advances quantum-enhanced sensing by establishing the thermodynamic\r\nlimit in a single transmon-cavity system and experimentally exploring a phase-conjugate receiver\r\nfor QI. These findings contribute to quantum metrology, particularly for weak signal detection\r\nand remote sensing in noisy environments.\r\n","lang":"eng"}],"acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"LifeSc"},{"_id":"SSU"}]},{"abstract":[{"lang":"eng","text":"The Tverberg theorem is one of the cornerstones of discrete geometry. It states that, given a set X of at least (d+1)(r−1)+1 points in Rd, one can find a partition X=X1∪⋯∪Xr of X, such that the convex hulls of the Xi, i=1,…,r, all share a common point. In this paper, we prove a trengthening of this theorem that guarantees a partition which, in addition to the above, has the property that the boundaries of full-dimensional convex hulls have pairwise nonempty intersections. Possible generalizations and algorithmic aspects are also discussed. As a concrete application, we show that any n points in the plane in general position span ⌊n/3⌋ vertex-disjoint triangles that are pairwise crossing, meaning that their boundaries have pairwise nonempty intersections; this number is clearly best possible. A previous result of Álvarez-Rebollar et al. guarantees ⌊n/6⌋pairwise crossing triangles. Our result generalizes to a result about simplices in Rd, d≥2."}],"volume":72,"quality_controlled":"1","date_created":"2023-08-06T22:01:12Z","external_id":{"arxiv":["1812.04911"],"isi":["001038546500001"]},"department":[{"_id":"UlWa"}],"language":[{"iso":"eng"}],"publication_status":"published","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.1812.04911"}],"acknowledgement":"Part of the research leading to this paper was done during the 16th Gremo Workshop on Open Problems (GWOP), Waltensburg, Switzerland, June 12–16, 2018. We thank Patrick Schnider for suggesting the problem, and Stefan Felsner, Malte Milatz, and Emo Welzl for fruitful discussions during the workshop. We also thank Stefan Felsner and Manfred Scheucher for finding, communicating the example from Sect. 3.3, and the kind permission to include their visualization of the point set. We thank Dömötör Pálvölgyi, the SoCG reviewers, and DCG reviewers for various helpful comments.\r\nR. Fulek gratefully acknowledges support from Austrian Science Fund (FWF), Project  M2281-N35. A. Kupavskii was supported by the Advanced Postdoc.Mobility Grant no. P300P2_177839 of the Swiss National Science Foundation. Research by P. Valtr was supported by the Grant no. 18-19158 S of the Czech Science Foundation (GAČR).","oa":1,"publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"scopus_import":"1","author":[{"first_name":"Radoslav","id":"39F3FFE4-F248-11E8-B48F-1D18A9856A87","last_name":"Fulek","full_name":"Fulek, Radoslav","orcid":"0000-0001-8485-1774"},{"first_name":"Bernd","last_name":"Gärtner","full_name":"Gärtner, Bernd"},{"first_name":"Andrey","full_name":"Kupavskii, Andrey","last_name":"Kupavskii"},{"first_name":"Pavel","full_name":"Valtr, Pavel","last_name":"Valtr"},{"first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","full_name":"Wagner, Uli","last_name":"Wagner","orcid":"0000-0002-1494-0568"}],"publication":"Discrete and Computational Geometry","isi":1,"intvolume":"        72","article_processing_charge":"No","related_material":{"record":[{"id":"6647","status":"public","relation":"earlier_version"}]},"citation":{"ama":"Fulek R, Gärtner B, Kupavskii A, Valtr P, Wagner U. The crossing Tverberg theorem. <i>Discrete and Computational Geometry</i>. 2024;72:831-848. doi:<a href=\"https://doi.org/10.1007/s00454-023-00532-x\">10.1007/s00454-023-00532-x</a>","apa":"Fulek, R., Gärtner, B., Kupavskii, A., Valtr, P., &#38; Wagner, U. (2024). The crossing Tverberg theorem. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-023-00532-x\">https://doi.org/10.1007/s00454-023-00532-x</a>","chicago":"Fulek, Radoslav, Bernd Gärtner, Andrey Kupavskii, Pavel Valtr, and Uli Wagner. “The Crossing Tverberg Theorem.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00454-023-00532-x\">https://doi.org/10.1007/s00454-023-00532-x</a>.","ista":"Fulek R, Gärtner B, Kupavskii A, Valtr P, Wagner U. 2024. The crossing Tverberg theorem. Discrete and Computational Geometry. 72, 831–848.","short":"R. Fulek, B. Gärtner, A. Kupavskii, P. Valtr, U. Wagner, Discrete and Computational Geometry 72 (2024) 831–848.","mla":"Fulek, Radoslav, et al. “The Crossing Tverberg Theorem.” <i>Discrete and Computational Geometry</i>, vol. 72, Springer Nature, 2024, pp. 831–48, doi:<a href=\"https://doi.org/10.1007/s00454-023-00532-x\">10.1007/s00454-023-00532-x</a>.","ieee":"R. Fulek, B. Gärtner, A. Kupavskii, P. Valtr, and U. Wagner, “The crossing Tverberg theorem,” <i>Discrete and Computational Geometry</i>, vol. 72. Springer Nature, pp. 831–848, 2024."},"_id":"13974","month":"09","title":"The crossing Tverberg theorem","article_type":"original","OA_type":"green","OA_place":"repository","doi":"10.1007/s00454-023-00532-x","arxiv":1,"day":"01","type":"journal_article","publisher":"Springer Nature","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"831-848","date_published":"2024-09-01T00:00:00Z","project":[{"grant_number":"M02281","_id":"261FA626-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Eliminating intersections in drawings of graphs"}],"date_updated":"2025-04-14T13:52:36Z","oa_version":"Preprint","year":"2024"},{"publication_status":"published","department":[{"_id":"HeEd"}],"external_id":{"isi":["001060727600004"],"arxiv":["2204.01076"],"pmid":["39610762"]},"date_created":"2023-09-17T22:01:10Z","corr_author":"1","language":[{"iso":"eng"}],"volume":72,"quality_controlled":"1","abstract":[{"text":"For a locally finite set in R2, the order-k Brillouin tessellations form an infinite sequence of convex face-to-face tilings of the plane. If the set is coarsely dense and generic, then the corresponding infinite sequences of minimum and maximum angles are both monotonic in k. As an example, a stationary Poisson point process in R2  is locally finite, coarsely dense, and generic with probability one. For such a set, the distributions of angles in the Voronoi tessellations, Delaunay mosaics, and Brillouin tessellations are independent of the order and can be derived from the formula for angles in order-1 Delaunay mosaics given by Miles (Math. Biosci. 6, 85–127 (1970)).","lang":"eng"}],"file_date_updated":"2024-07-22T09:43:19Z","author":[{"full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9823-6833"},{"last_name":"Garber","full_name":"Garber, Alexey","first_name":"Alexey"},{"first_name":"Mohadese","last_name":"Ghafari","full_name":"Ghafari, Mohadese"},{"orcid":"0000-0002-1780-2689","first_name":"Teresa","id":"4879BB4E-F248-11E8-B48F-1D18A9856A87","full_name":"Heiss, Teresa","last_name":"Heiss"},{"id":"f86f7148-b140-11ec-9577-95435b8df824","first_name":"Morteza","last_name":"Saghafian","full_name":"Saghafian, Morteza"}],"publication":"Discrete and Computational Geometry","scopus_import":"1","ec_funded":1,"isi":1,"intvolume":"        72","file":[{"success":1,"relation":"main_file","access_level":"open_access","file_id":"17301","date_created":"2024-07-22T09:43:19Z","file_name":"2024_DiscreteComputGeom_Edelsbrunner.pdf","creator":"dernst","file_size":892019,"checksum":"b207b4e00f904e8ea8a30e24f0251f79","content_type":"application/pdf","date_updated":"2024-07-22T09:43:19Z"}],"acknowledgement":"Work by all authors but A. Garber is supported by the European Research Council (ERC), Grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF), Grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), Grant No. I 02979-N35. Work by A. Garber is partially supported by the Alexander von Humboldt Foundation.","pmid":1,"oa":1,"publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"arxiv":1,"ddc":["510"],"doi":"10.1007/s00454-023-00566-1","article_type":"original","_id":"14345","title":"On angles in higher order Brillouin tessellations and related tilings in the plane","month":"07","article_processing_charge":"Yes (via OA deal)","citation":{"ama":"Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. On angles in higher order Brillouin tessellations and related tilings in the plane. <i>Discrete and Computational Geometry</i>. 2024;72:29-48. doi:<a href=\"https://doi.org/10.1007/s00454-023-00566-1\">10.1007/s00454-023-00566-1</a>","apa":"Edelsbrunner, H., Garber, A., Ghafari, M., Heiss, T., &#38; Saghafian, M. (2024). On angles in higher order Brillouin tessellations and related tilings in the plane. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-023-00566-1\">https://doi.org/10.1007/s00454-023-00566-1</a>","chicago":"Edelsbrunner, Herbert, Alexey Garber, Mohadese Ghafari, Teresa Heiss, and Morteza Saghafian. “On Angles in Higher Order Brillouin Tessellations and Related Tilings in the Plane.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00454-023-00566-1\">https://doi.org/10.1007/s00454-023-00566-1</a>.","ista":"Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. 2024. On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. 72, 29–48.","short":"H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, M. Saghafian, Discrete and Computational Geometry 72 (2024) 29–48.","mla":"Edelsbrunner, Herbert, et al. “On Angles in Higher Order Brillouin Tessellations and Related Tilings in the Plane.” <i>Discrete and Computational Geometry</i>, vol. 72, Springer Nature, 2024, pp. 29–48, doi:<a href=\"https://doi.org/10.1007/s00454-023-00566-1\">10.1007/s00454-023-00566-1</a>.","ieee":"H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, and M. Saghafian, “On angles in higher order Brillouin tessellations and related tilings in the plane,” <i>Discrete and Computational Geometry</i>, vol. 72. Springer Nature, pp. 29–48, 2024."},"date_published":"2024-07-01T00:00:00Z","project":[{"call_identifier":"H2020","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","grant_number":"788183"},{"_id":"268116B8-B435-11E9-9278-68D0E5697425","grant_number":"Z00342","call_identifier":"FWF","name":"Mathematics, Computer Science"},{"grant_number":"I02979-N35","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Persistence and stability of geometric complexes"}],"has_accepted_license":"1","year":"2024","oa_version":"Published Version","date_updated":"2025-04-23T08:41:59Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"29-48","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","day":"01","publisher":"Springer Nature"},{"keyword":["Neurology (clinical)"],"author":[{"first_name":"Rauan","full_name":"Kaiyrzhanov, Rauan","last_name":"Kaiyrzhanov"},{"first_name":"Aboulfazl","full_name":"Rad, Aboulfazl","last_name":"Rad"},{"last_name":"Lin","full_name":"Lin, Sheng-Jia","first_name":"Sheng-Jia"},{"first_name":"Aida","full_name":"Bertoli-Avella, Aida","last_name":"Bertoli-Avella"},{"last_name":"Kallemeijn","full_name":"Kallemeijn, Wouter W","first_name":"Wouter W"},{"first_name":"Annie","full_name":"Godwin, Annie","last_name":"Godwin"},{"first_name":"Maha S","last_name":"Zaki","full_name":"Zaki, Maha S"},{"orcid":"0000-0002-2512-7812","id":"3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3","first_name":"Kevin","last_name":"Huang","full_name":"Huang, Kevin"},{"last_name":"Lau","full_name":"Lau, Tracy","first_name":"Tracy"},{"first_name":"Cassidy","full_name":"Petree, Cassidy","last_name":"Petree"},{"full_name":"Efthymiou, Stephanie","last_name":"Efthymiou","first_name":"Stephanie"},{"full_name":"Ghayoor Karimiani, Ehsan","last_name":"Ghayoor Karimiani","first_name":"Ehsan"},{"full_name":"Hempel, Maja","last_name":"Hempel","first_name":"Maja"},{"full_name":"Normand, Elizabeth A","last_name":"Normand","first_name":"Elizabeth A"},{"last_name":"Rudnik-Schöneborn","full_name":"Rudnik-Schöneborn, Sabine","first_name":"Sabine"},{"full_name":"Schatz, Ulrich A","last_name":"Schatz","first_name":"Ulrich A"},{"first_name":"Marc P","full_name":"Baggelaar, Marc P","last_name":"Baggelaar"},{"first_name":"Muhammad","full_name":"Ilyas, Muhammad","last_name":"Ilyas"},{"full_name":"Sultan, Tipu","last_name":"Sultan","first_name":"Tipu"},{"last_name":"Alvi","full_name":"Alvi, Javeria Raza","first_name":"Javeria Raza"},{"first_name":"Manizha","last_name":"Ganieva","full_name":"Ganieva, Manizha"},{"first_name":"Ben","last_name":"Fowler","full_name":"Fowler, Ben"},{"first_name":"Ruxandra","full_name":"Aanicai, Ruxandra","last_name":"Aanicai"},{"first_name":"Gulsen","last_name":"Akay 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W","full_name":"Tate, Edward W","last_name":"Tate"},{"first_name":"Gaurav K","last_name":"Varshney","full_name":"Varshney, Gaurav K"},{"first_name":"Henry","full_name":"Houlden, Henry","last_name":"Houlden"},{"full_name":"Maroofian, Reza","last_name":"Maroofian","first_name":"Reza"}],"scopus_import":"1","publication":"Brain","file_date_updated":"2024-07-16T08:22:13Z","intvolume":"       147","pmid":1,"file":[{"success":1,"access_level":"open_access","relation":"main_file","creator":"dernst","file_name":"2024_Brain_Kaiyrzhanov.pdf","file_id":"17254","date_created":"2024-07-16T08:22:13Z","file_size":2641456,"content_type":"application/pdf","checksum":"0ee7a8ab9300225d60968f7a3e3cfa0d","date_updated":"2024-07-16T08:22:13Z"}],"publication_identifier":{"eissn":["1460-2156"],"issn":["0006-8950"]},"oa":1,"publication_status":"published","date_created":"2023-11-16T12:36:51Z","external_id":{"pmid":["37951597"]},"department":[{"_id":"GradSch"}],"language":[{"iso":"eng"}],"volume":147,"quality_controlled":"1","abstract":[{"lang":"eng","text":"The acyl-CoA-binding domain-containing protein 6 (ACBD6) is ubiquitously expressed, plays a role in the acylation of lipids and proteins, and regulates the N-myristoylation of proteins via N-myristoyltransferase enzymes (NMTs). However, its precise function in cells is still unclear, as is the consequence of ACBD6 defects on human pathophysiology. Utilizing exome sequencing and extensive international data sharing efforts, we identified 45 affected individuals from 28 unrelated families (consanguinity 93%) with bi-allelic pathogenic, predominantly loss-of-function (18/20) variants in ACBD6. We generated zebrafish and Xenopus tropicalis acbd6 knockouts by CRISPR/Cas9 and characterized the role of ACBD6 on protein N-myristoylation with YnMyr chemical proteomics in the model organisms and human cells, with the latter also being subjected further to ACBD6 peroxisomal localization studies. The affected individuals (23 males and 22 females), with ages ranging from 1 to 50 years old, typically present with a complex and progressive disease involving moderate-to-severe global developmental delay/intellectual disability (100%) with significant expressive language impairment (98%), movement disorders (97%), facial dysmorphism (95%), and mild cerebellar ataxia (85%) associated with gait impairment (94%), limb spasticity/hypertonia (76%), oculomotor (71%) and behavioural abnormalities (65%), overweight (59%), microcephaly (39%) and epilepsy (33%). The most conspicuous and common movement disorder was dystonia (94%), frequently leading to early-onset progressive postural deformities (97%), limb dystonia (55%), and cervical dystonia (31%). A jerky tremor in the upper limbs (63%), a mild head tremor (59%), parkinsonism/hypokinesia developing with advancing age (32%), and simple motor and vocal tics were among other frequent movement disorders. Midline brain malformations including corpus callosum abnormalities (70%), hypoplasia/agenesis of the anterior commissure (66%), short midbrain and small inferior cerebellar vermis (38% each), as well as hypertrophy of the clava (24%) were common neuroimaging findings. acbd6-deficient zebrafish and Xenopus models effectively recapitulated many clinical phenotypes reported in patients including movement disorders, progressive neuromotor impairment, seizures, microcephaly, craniofacial dysmorphism, and midbrain defects accompanied by developmental delay with increased mortality over time. Unlike ACBD5, ACBD6 did not show a peroxisomal localisation and ACBD6-deficiency was not associated with altered peroxisomal parameters in patient fibroblasts. Significant differences in YnMyr-labelling were observed for 68 co- and 18 post-translationally N-myristoylated proteins in patient-derived fibroblasts. N-Myristoylation was similarly affected in acbd6-deficient zebrafish and Xenopus tropicalis models, including Fus, Marcks, and Chchd-related proteins implicated in neurological diseases. The present study provides evidence that bi-allelic pathogenic variants in ACBD6 lead to a distinct neurodevelopmental syndrome accompanied by complex and progressive cognitive and movement disorders."}],"date_published":"2024-04-01T00:00:00Z","has_accepted_license":"1","date_updated":"2024-07-16T08:23:24Z","year":"2024","oa_version":"Submitted Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"1436-1456","extern":"1","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"issue":"4","day":"01","publisher":"Oxford University Press","type":"journal_article","ddc":["570"],"article_type":"original","doi":"10.1093/brain/awad380","_id":"14543","month":"04","title":"Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders","article_processing_charge":"No","citation":{"ama":"Kaiyrzhanov R, Rad A, Lin S-J, et al. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. <i>Brain</i>. 2024;147(4):1436-1456. doi:<a href=\"https://doi.org/10.1093/brain/awad380\">10.1093/brain/awad380</a>","apa":"Kaiyrzhanov, R., Rad, A., Lin, S.-J., Bertoli-Avella, A., Kallemeijn, W. W., Godwin, A., … Maroofian, R. (2024). Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. <i>Brain</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/brain/awad380\">https://doi.org/10.1093/brain/awad380</a>","chicago":"Kaiyrzhanov, Rauan, Aboulfazl Rad, Sheng-Jia Lin, Aida Bertoli-Avella, Wouter W Kallemeijn, Annie Godwin, Maha S Zaki, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.” <i>Brain</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/brain/awad380\">https://doi.org/10.1093/brain/awad380</a>.","ista":"Kaiyrzhanov R, Rad A, Lin S-J, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Ghayoor Karimiani E, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Akay Tayfun G, Al Saman A, Alswaid A, Amiri N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Bahrami Monajemi G, Mohammadi P, Samie S, Banu SH, Basto JP, Kortüm F, Bauer M, Bauer P, Beetz C, Garshasbi M, Hameed Issa A, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D, Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW, Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M, Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R. 2024. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. 147(4), 1436–1456.","mla":"Kaiyrzhanov, Rauan, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.” <i>Brain</i>, vol. 147, no. 4, Oxford University Press, 2024, pp. 1436–56, doi:<a href=\"https://doi.org/10.1093/brain/awad380\">10.1093/brain/awad380</a>.","short":"R. Kaiyrzhanov, A. Rad, S.-J. Lin, A. Bertoli-Avella, W.W. Kallemeijn, A. Godwin, M.S. Zaki, K. Huang, T. Lau, C. Petree, S. Efthymiou, E. Ghayoor Karimiani, M. Hempel, E.A. Normand, S. Rudnik-Schöneborn, U.A. Schatz, M.P. Baggelaar, M. Ilyas, T. Sultan, J.R. Alvi, M. Ganieva, B. Fowler, R. Aanicai, G. Akay Tayfun, A. Al Saman, A. Alswaid, N. Amiri, N. Asilova, V. Shotelersuk, P. Yeetong, M. Azam, M. Babaei, G. Bahrami Monajemi, P. Mohammadi, S. Samie, S.H. Banu, J.P. Basto, F. Kortüm, M. Bauer, P. Bauer, C. Beetz, M. Garshasbi, A. Hameed Issa, W. Eyaid, H. Ahmed, N. Hashemi, K. Hassanpour, I. Herman, S. Ibrohimov, B.A. Abdul-Majeed, M. Imdad, M. Isrofilov, Q. Kaiyal, S. Khan, B. Kirmse, J. Koster, C.M. Lourenço, T. Mitani, O. Moldovan, D. Murphy, M. Najafi, D. Pehlivan, M.E. Rocha, V. Salpietro, M. Schmidts, A. Shalata, M. Mahroum, J.K. Talbeya, R.W. Taylor, D. Vazquez, A. Vetro, H.R. Waterham, M. Zaman, T.A. Schrader, W.K. Chung, R. Guerrini, J.R. Lupski, J. Gleeson, M. Suri, Y. Jamshidi, K.P. Bhatia, B. Vona, M. Schrader, M. Severino, M. Guille, E.W. Tate, G.K. Varshney, H. Houlden, R. Maroofian, Brain 147 (2024) 1436–1456.","ieee":"R. Kaiyrzhanov <i>et al.</i>, “Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders,” <i>Brain</i>, vol. 147, no. 4. Oxford University Press, pp. 1436–1456, 2024."}},{"quality_controlled":"1","volume":689,"article_number":"A44","abstract":[{"text":"The increasingly neutral intergalactic gas at z > 6 impacts the Lyman-α (Lyα) flux observed from galaxies. One luminous galaxy, COLA1, stands out because of its unique double-peaked Lyα line at z = 6.6, unseen in any simulation of reionization. Here, we present JWST/NIRCam wide-field slitless spectroscopy in a 21 arcmin2 field centered on COLA1. We find 141 galaxies spectroscopically selected through the [O III] doublet at 5.35 < z < 6.95, with 40 of these sources showing Hβ. For COLA1, we additionally detect [O III]4363 as well as Hγ. We measure a systemic redshift of z = 6.5917 for COLA1, confirming the classical double-peak nature of the Lyα profile. This implies that it resides in a highly ionized bubble and that it is leaking ionizing photons with a high escape fraction of fesc(LyC) = 20–50%, making it a prime laboratory to study Lyman continuum escape in the Epoch of Reionization. COLA1 shows all the signs of a prolific ionizer with a Lyα escape fraction of 81 ± 5%, Balmer decrement indicating no dust, a steep UV slope (βUV = −3.2 ± 0.4), and a star-formation surface density ≳10× that of typical galaxies at similar redshift. We detect five galaxies in COLA1’s close environment (Δz < 0.02). Exploiting the high spectroscopic completeness inherent to grism surveys, and using mock simulations that fully mimic the selection function, we show that the number of detected companions is very typical for a normal similarly UV-bright (MUV ∼ −21.3) galaxy – that is, the ionized bubble around COLA1 is unlikely to be due to an excessively large over-density. Instead, the measured ionizing properties suggest that COLA1 by itself might be powering the bubble required to explain its double-peaked Lyα profile (Rion ≈ 0.7 pMpc), with only minor contributions from detected neighbors (−19.5 ≲ MUV ≲ −17.5).","lang":"eng"}],"publication_status":"published","language":[{"iso":"eng"}],"date_created":"2024-09-08T22:01:11Z","department":[{"_id":"JoMa"}],"external_id":{"arxiv":["2404.10040"],"isi":["001303205700016"]},"oa":1,"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"acknowledgement":"The authors acknowledge the financial support from the MICIU with funding from the European Union NextGenerationEU and Generalitat Valenciana in the call Programa de Planes Complementarios de I+D+i (PRTR 2022) Project (VAL-JPAS), reference ASFAE/2022/025. This work has been funded by project PID2019-109592GBI00/AEI/10.13039/501100011033 from the Spanish Ministerio de Ciencia e Innovación (MCIN)-Agencia Estatal de Investigación, by the Project of Excellence Prometeo/2020/085 from the Conselleria d’Innovació Universitats, Ciència i Societat Digital de la Generalitat Valenciana. It has also be funded by the Project of Excellence Prometeo/2020/085 from the Conselleria d’Educació, Universitats, i Ocupació de la Generalitat Valenciana. Funded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. ST acknowledges support by the Royal Society Research Grant G125142. AH acknowledges support by the VILLUM FONDEN under grant 37459. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant DNRF140. We acknowledge funding from JWST program GO-1933. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program # 1933. The specific observations analyzed can be accessed via https://doi.org/10.17909/s9ht-7n34.","file":[{"file_size":6225413,"creator":"dernst","file_name":"2024_AstronomyAstrophysics_TorralbaTorregrosa.pdf","date_created":"2024-09-11T07:35:00Z","file_id":"18055","date_updated":"2024-09-11T07:35:00Z","content_type":"application/pdf","checksum":"a6c0df287c75e8929db9f42badeac859","success":1,"access_level":"open_access","relation":"main_file"}],"intvolume":"       689","isi":1,"scopus_import":"1","file_date_updated":"2024-09-11T07:35:00Z","author":[{"first_name":"Alberto","full_name":"Torralba-Torregrosa, Alberto","last_name":"Torralba-Torregrosa"},{"orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J"},{"last_name":"Naidu","full_name":"Naidu, Rohan P.","first_name":"Rohan P."},{"first_name":"Ruari","full_name":"Mackenzie, Ruari","last_name":"Mackenzie"},{"first_name":"Gabriele","full_name":"Pezzulli, Gabriele","last_name":"Pezzulli"},{"full_name":"Hutter, Anne","last_name":"Hutter","first_name":"Anne"},{"first_name":"Pablo","full_name":"Arnalte-Mur, Pablo","last_name":"Arnalte-Mur"},{"last_name":"Gurung-López","full_name":"Gurung-López, Siddhartha","first_name":"Siddhartha"},{"first_name":"Sandro","last_name":"Tacchella","full_name":"Tacchella, Sandro"},{"first_name":"Pascal","full_name":"Oesch, Pascal","last_name":"Oesch"},{"last_name":"Kashino","full_name":"Kashino, Daichi","first_name":"Daichi"},{"full_name":"Conroy, Charlie","last_name":"Conroy","first_name":"Charlie"},{"last_name":"Sobral","full_name":"Sobral, David","first_name":"David"}],"publication":"Astronomy and Astrophysics","month":"09","title":"Anatomy of an ionized bubble: NIRCam grism spectroscopy of the z = 6.6 double-peaked Lyman- α emitter COLA1 and its environment","_id":"17889","citation":{"mla":"Torralba-Torregrosa, Alberto, et al. “Anatomy of an Ionized Bubble: NIRCam Grism Spectroscopy of the z = 6.6 Double-Peaked Lyman- α Emitter COLA1 and Its Environment.” <i>Astronomy and Astrophysics</i>, vol. 689, A44, EDP Sciences, 2024, doi:<a href=\"https://doi.org/10.1051/0004-6361/202450318\">10.1051/0004-6361/202450318</a>.","short":"A. Torralba-Torregrosa, J.J. Matthee, R.P. Naidu, R. Mackenzie, G. Pezzulli, A. Hutter, P. Arnalte-Mur, S. Gurung-López, S. Tacchella, P. Oesch, D. Kashino, C. Conroy, D. Sobral, Astronomy and Astrophysics 689 (2024).","ieee":"A. Torralba-Torregrosa <i>et al.</i>, “Anatomy of an ionized bubble: NIRCam grism spectroscopy of the z = 6.6 double-peaked Lyman- α emitter COLA1 and its environment,” <i>Astronomy and Astrophysics</i>, vol. 689. EDP Sciences, 2024.","apa":"Torralba-Torregrosa, A., Matthee, J. J., Naidu, R. P., Mackenzie, R., Pezzulli, G., Hutter, A., … Sobral, D. (2024). Anatomy of an ionized bubble: NIRCam grism spectroscopy of the z = 6.6 double-peaked Lyman- α emitter COLA1 and its environment. <i>Astronomy and Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202450318\">https://doi.org/10.1051/0004-6361/202450318</a>","ama":"Torralba-Torregrosa A, Matthee JJ, Naidu RP, et al. Anatomy of an ionized bubble: NIRCam grism spectroscopy of the z = 6.6 double-peaked Lyman- α emitter COLA1 and its environment. <i>Astronomy and Astrophysics</i>. 2024;689. doi:<a href=\"https://doi.org/10.1051/0004-6361/202450318\">10.1051/0004-6361/202450318</a>","ista":"Torralba-Torregrosa A, Matthee JJ, Naidu RP, Mackenzie R, Pezzulli G, Hutter A, Arnalte-Mur P, Gurung-López S, Tacchella S, Oesch P, Kashino D, Conroy C, Sobral D. 2024. Anatomy of an ionized bubble: NIRCam grism spectroscopy of the z = 6.6 double-peaked Lyman- α emitter COLA1 and its environment. Astronomy and Astrophysics. 689, A44.","chicago":"Torralba-Torregrosa, Alberto, Jorryt J Matthee, Rohan P. Naidu, Ruari Mackenzie, Gabriele Pezzulli, Anne Hutter, Pablo Arnalte-Mur, et al. “Anatomy of an Ionized Bubble: NIRCam Grism Spectroscopy of the z = 6.6 Double-Peaked Lyman- α Emitter COLA1 and Its Environment.” <i>Astronomy and Astrophysics</i>. EDP Sciences, 2024. <a href=\"https://doi.org/10.1051/0004-6361/202450318\">https://doi.org/10.1051/0004-6361/202450318</a>."},"article_processing_charge":"Yes (in subscription journal)","ddc":["520"],"arxiv":1,"article_type":"original","doi":"10.1051/0004-6361/202450318","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","type":"journal_article","publisher":"EDP Sciences","day":"01","date_updated":"2025-09-08T09:20:52Z","oa_version":"Published Version","year":"2024","date_published":"2024-09-01T00:00:00Z","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"language":[{"iso":"eng"}],"corr_author":"1","date_created":"2024-10-27T23:01:45Z","external_id":{"isi":["001329804200001"],"arxiv":["2306.12301"]},"department":[{"_id":"VaKa"}],"publication_status":"published","abstract":[{"lang":"eng","text":"In this paper we prove a perturbative version of a remarkable Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) result. They prove non perturbative Birkhoff conjecture for centrally-symmetric convex domains, namely, a centrally-symmetric convex domain with integrable billiard is ellipse. We combine techniques from Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) with a local result by Kaloshin–Sorrentino (Ann. Math. 188(1):315–380, 2018) and show that a domain close enough to a centrally symmetric one with integrable billiard is ellipse. To combine these results we derive a slight extension of Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) by proving that a notion of rational integrability is equivalent to the C0-integrability condition used in their paper."}],"quality_controlled":"1","volume":34,"isi":1,"intvolume":"        34","ec_funded":1,"author":[{"id":"FE553552-CDE8-11E9-B324-C0EBE5697425","first_name":"Vadim","full_name":"Kaloshin, Vadim","last_name":"Kaloshin","orcid":"0000-0002-6051-2628"},{"orcid":"0000-0003-2640-4049","last_name":"Koudjinan","full_name":"Koudjinan, Edmond","first_name":"Edmond","id":"52DF3E68-AEFA-11EA-95A4-124A3DDC885E"},{"last_name":"Zhang","full_name":"Zhang, Ke","first_name":"Ke"}],"publication":"Geometric and Functional Analysis","scopus_import":"1","file_date_updated":"2025-01-13T09:14:24Z","publication_identifier":{"issn":["1016-443X"],"eissn":["1420-8970"]},"oa":1,"file":[{"file_name":"2024_GeometricFunctionalAnalysis_Kaloshin.pdf","creator":"dernst","file_id":"18833","date_created":"2025-01-13T09:14:24Z","file_size":2260980,"checksum":"e7fcd9f78beb40408c7d858ac0625e27","content_type":"application/pdf","date_updated":"2025-01-13T09:14:24Z","success":1,"access_level":"open_access","relation":"main_file"}],"acknowledgement":"We are grateful to the anonymous referee for their careful reading and valuable remarks and comments which helped to improve significantly the paper. Open access funding provided by Institute of Science and Technology (IST Austria). V.K. and C.E.K. gratefully acknowledge support from the European Research Council (ERC) through the Advanced Grant “SPERIG” (#885 707).","OA_type":"hybrid","article_type":"original","doi":"10.1007/s00039-024-00695-6","OA_place":"publisher","ddc":["510"],"arxiv":1,"citation":{"ieee":"V. Kaloshin, E. Koudjinan, and K. Zhang, “Birkhoff conjecture for nearly centrally symmetric domains,” <i>Geometric and Functional Analysis</i>, vol. 34. Springer Nature, pp. 1973–2007, 2024.","short":"V. Kaloshin, E. Koudjinan, K. Zhang, Geometric and Functional Analysis 34 (2024) 1973–2007.","mla":"Kaloshin, Vadim, et al. “Birkhoff Conjecture for Nearly Centrally Symmetric Domains.” <i>Geometric and Functional Analysis</i>, vol. 34, Springer Nature, 2024, pp. 1973–2007, doi:<a href=\"https://doi.org/10.1007/s00039-024-00695-6\">10.1007/s00039-024-00695-6</a>.","ista":"Kaloshin V, Koudjinan E, Zhang K. 2024. Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. 34, 1973–2007.","chicago":"Kaloshin, Vadim, Edmond Koudjinan, and Ke Zhang. “Birkhoff Conjecture for Nearly Centrally Symmetric Domains.” <i>Geometric and Functional Analysis</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00039-024-00695-6\">https://doi.org/10.1007/s00039-024-00695-6</a>.","apa":"Kaloshin, V., Koudjinan, E., &#38; Zhang, K. (2024). Birkhoff conjecture for nearly centrally symmetric domains. <i>Geometric and Functional Analysis</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00039-024-00695-6\">https://doi.org/10.1007/s00039-024-00695-6</a>","ama":"Kaloshin V, Koudjinan E, Zhang K. Birkhoff conjecture for nearly centrally symmetric domains. <i>Geometric and Functional Analysis</i>. 2024;34:1973-2007. doi:<a href=\"https://doi.org/10.1007/s00039-024-00695-6\">10.1007/s00039-024-00695-6</a>"},"article_processing_charge":"Yes (via OA deal)","month":"12","title":"Birkhoff conjecture for nearly centrally symmetric domains","_id":"18483","page":"1973-2007","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_updated":"2025-09-08T14:27:45Z","oa_version":"Published Version","year":"2024","date_published":"2024-12-01T00:00:00Z","project":[{"grant_number":"885707","_id":"9B8B92DE-BA93-11EA-9121-9846C619BF3A","call_identifier":"H2020","name":"Spectral rigidity and integrability for billiards and geodesic flows"}],"has_accepted_license":"1","day":"01","type":"journal_article","publisher":"Springer Nature","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public"},{"publication_status":"published","external_id":{"arxiv":["2408.00517"],"isi":["001339205700015"]},"department":[{"_id":"JoMa"}],"date_created":"2024-11-03T23:01:45Z","language":[{"iso":"eng"}],"volume":690,"quality_controlled":"1","abstract":[{"lang":"eng","text":"Context. The escape of Lyman-α photons at redshifts greater than two is an ongoing subject of study and an important quantity to further understanding of Lyman-α emitters (LAEs), the transmission of Lyman-α photons through the interstellar medium and intergalactic medium, and the impact these LAEs have on cosmic reionisation.\r\n\r\nAims. This study aims to assess the Lyman-α escape fraction, fesc, Lyα, over the redshift range 2.9 < z < 6.7, focusing on Very Large Telescope/Multi Unit Spectroscopic Explorer (VLT/MUSE) selected, gravitationally lensed, intrinsically faint LAEs. These galaxies are of particular interest as the potential drivers of cosmic reionisation.\r\n\r\nMethods. We assessed fesc, Lyα in two ways: through an individual study of 96 LAEs behind the A2744 lensing cluster, with James Webb Space Telescope/Near-Infrared Camera (JWST/NIRCam) and HST data, and through a study of the global evolution of fesc, Lyα using the state-of-the-art luminosity functions for LAEs and the UV-selected ‘parent’ population (dust-corrected). We compared these studies to those in the literature based on brighter samples.\r\n\r\nResults. We find a negligible redshift evolution of fesc, Lyα for our individual galaxies; it is likely that it was washed out by significant intrinsic scatter. We observed a more significant evolution towards higher escape fractions with decreasing UV magnitude and fit this relation. When comparing the two luminosity functions to derive fesc, Lyα in a global sense, we saw agreement with previous literature when integrating the luminosity functions to a bright limit. However, when integrating using a faint limit equivalent to the observational limits of our samples, we observed enhanced values of fesc, Lyα, particularly around z ∼ 6, where fesc, Lyα becomes consistent with 100% escape. This indicates for the faint regimes we sampled that galaxies towards reionisation tend to allow very large fractions of Lyman-α photons to escape. We interpret this as evidence of a lack of any significant dust in these populations; our sample is likely dominated by young, highly star-forming chemically unevolved galaxies. Finally, we assessed the contribution of the LAE population to reionisation using our latest values for fesc, Lyα and the LAE luminosity density. The dependence on the escape fraction of Lyman continuum photons is strong, but for values similar to those observed recently in z ∼ 3 LAEs and high-redshift analogues, LAEs could provide all the ionising emissivity necessary for reionisation."}],"article_number":"A302","scopus_import":"1","file_date_updated":"2024-11-04T08:04:44Z","publication":"Astronomy and Astrophysics","author":[{"first_name":"I.","full_name":"Goovaerts, I.","last_name":"Goovaerts"},{"full_name":"Thai, T. T.","last_name":"Thai","first_name":"T. T."},{"last_name":"Pello","full_name":"Pello, R.","first_name":"R."},{"full_name":"Tuan-Anh, P.","last_name":"Tuan-Anh","first_name":"P."},{"last_name":"Laporte","full_name":"Laporte, N.","first_name":"N."},{"id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee","full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X"},{"first_name":"T.","last_name":"Nanayakkara","full_name":"Nanayakkara, T."},{"first_name":"J.","last_name":"Pharo","full_name":"Pharo, J."}],"intvolume":"       690","isi":1,"file":[{"relation":"main_file","access_level":"open_access","success":1,"checksum":"4007e2b0fadf93bea61c5bec3fc97e87","content_type":"application/pdf","date_updated":"2024-11-04T08:04:44Z","date_created":"2024-11-04T08:04:44Z","file_id":"18495","file_name":"2024_AstronomyAstrophysics_Goovaerts.pdf","creator":"dernst","file_size":2008461}],"acknowledgement":"This work is done based on observations made with ESO Telescopes at the La Silla Paranal Observatory under programme IDs 060.A-9345, 092.A-0472, 094.A-0115, 095.A-0181, 096.A-0710, 097.A0269, 100.A-0249, and 294.A-5032. Also based on observations obtained with the\r\nNASA/ESA Hubble Space Telescope, retrieved from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute (STScI). STScI is operated by the Association of Universities for Research in Astronomy, Inc. under NASA contract NAS 5-26555. All plots in this paper were created using Matplotlib (Hunter 2007). Part of this work was supported by the French CNRS, the Aix-Marseille University, the French Programme National de Cosmologie et Galaxies (PNCG) of CNRS/INSU with INP and IN2P3, co-funded by CEA and CNES. This work also received support from the French government under the France 2030 investment plan, as part of the Excellence Initiative of Aix-Marseille University - A*MIDEX (AMX-19-IET-008 - IPhU).\r\nFinancial support from the World Laboratory, the Odon Vallet Foundation and VNSC is gratefully acknowledged. Tran Thi Thai was funded by Vingroup JSC and supported by the Master, PhD Scholarship Programme of Vingroup Innovation Foundation (VINIF), Institute of Big Data, code VINIF.2023.TS.108. This research was funded by Vingroup Innovation Foundation under project code VINIF.2023.DA.057.","oa":1,"publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"arxiv":1,"ddc":["520"],"OA_place":"publisher","doi":"10.1051/0004-6361/202451432","OA_type":"diamond","article_type":"original","_id":"18493","title":"Charting the Lyman-α escape fraction in the range 2.9 < z < 6.7 and consequences for the LAE reionisation contribution","month":"10","article_processing_charge":"No","citation":{"apa":"Goovaerts, I., Thai, T. T., Pello, R., Tuan-Anh, P., Laporte, N., Matthee, J. J., … Pharo, J. (2024). Charting the Lyman-α escape fraction in the range 2.9 &#60; z &#60; 6.7 and consequences for the LAE reionisation contribution. <i>Astronomy and Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202451432\">https://doi.org/10.1051/0004-6361/202451432</a>","ama":"Goovaerts I, Thai TT, Pello R, et al. Charting the Lyman-α escape fraction in the range 2.9 &#60; z &#60; 6.7 and consequences for the LAE reionisation contribution. <i>Astronomy and Astrophysics</i>. 2024;690. doi:<a href=\"https://doi.org/10.1051/0004-6361/202451432\">10.1051/0004-6361/202451432</a>","ista":"Goovaerts I, Thai TT, Pello R, Tuan-Anh P, Laporte N, Matthee JJ, Nanayakkara T, Pharo J. 2024. Charting the Lyman-α escape fraction in the range 2.9 &#60; z &#60; 6.7 and consequences for the LAE reionisation contribution. Astronomy and Astrophysics. 690, A302.","chicago":"Goovaerts, I., T. T. Thai, R. Pello, P. Tuan-Anh, N. Laporte, Jorryt J Matthee, T. Nanayakkara, and J. Pharo. “Charting the Lyman-α Escape Fraction in the Range 2.9 &#60; z &#60; 6.7 and Consequences for the LAE Reionisation Contribution.” <i>Astronomy and Astrophysics</i>. EDP Sciences, 2024. <a href=\"https://doi.org/10.1051/0004-6361/202451432\">https://doi.org/10.1051/0004-6361/202451432</a>.","mla":"Goovaerts, I., et al. “Charting the Lyman-α Escape Fraction in the Range 2.9 &#60; z &#60; 6.7 and Consequences for the LAE Reionisation Contribution.” <i>Astronomy and Astrophysics</i>, vol. 690, A302, EDP Sciences, 2024, doi:<a href=\"https://doi.org/10.1051/0004-6361/202451432\">10.1051/0004-6361/202451432</a>.","short":"I. Goovaerts, T.T. Thai, R. Pello, P. Tuan-Anh, N. Laporte, J.J. Matthee, T. Nanayakkara, J. Pharo, Astronomy and Astrophysics 690 (2024).","ieee":"I. Goovaerts <i>et al.</i>, “Charting the Lyman-α escape fraction in the range 2.9 &#60; z &#60; 6.7 and consequences for the LAE reionisation contribution,” <i>Astronomy and Astrophysics</i>, vol. 690. EDP Sciences, 2024."},"has_accepted_license":"1","date_published":"2024-10-01T00:00:00Z","oa_version":"Published Version","year":"2024","date_updated":"2025-09-08T14:28:28Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"day":"01","publisher":"EDP Sciences","type":"journal_article"},{"date_created":"2024-11-03T23:01:45Z","department":[{"_id":"JoMa"}],"external_id":{"isi":["001338877100001"]},"language":[{"iso":"eng"}],"publication_status":"published","article_number":"275","abstract":[{"lang":"eng","text":"We expect luminous (M 1450 ≲ −26.5) high-redshift quasars to trace the highest-density peaks in the early Universe. Here, we present observations of four z ≳ 6 quasar fields using JWST/NIRCam in the imaging and wide-field slitless spectroscopy mode and report a wide range in the number of detected [O iii]-emitting galaxies in the quasars’ environments, ranging between a density enhancement of δ ≈ 65 within a 2 cMpc radius—one of the largest protoclusters during the Epoch of Reionization discovered to date—to a density contrast consistent with zero, indicating the presence of a UV-luminous quasar in a region comparable to the average density of the Universe. By measuring the two-point cross-correlation function of quasars and their surrounding galaxies, as well as the galaxy autocorrelation function, we infer a correlation length of quasars at 〈z〉 = 6.25 of r 0 QQ = 22.0 − 2.9 + 3.0 cMpc h − 1 , while we obtain a correlation length of the [O iii]-emitting galaxies of r 0 GG = 4.1 ± 0.3 cMpc h − 1 . By comparing the correlation functions to dark-matter-only simulations we estimate the minimum mass of the quasars’ host dark matter halos to be log 10 ( M halo , min / M ⊙ ) = 12.43 − 0.15 + 0.13 (and log 10 ( M halo , min [ OIII ] / M ⊙ ) = 10.56 − 0.03 + 0.05 for the [O iii] emitters), indicating that (a) luminous quasars do not necessarily reside within the most overdense regions in the early Universe, and that (b) the UV-luminous duty cycle of quasar activity at these redshifts is f duty ≪ 1. Such short quasar activity timescales challenge our understanding of early supermassive black hole growth and provide evidence for highly dust-obscured growth phases or episodic, radiatively inefficient accretion rates."}],"volume":974,"quality_controlled":"1","author":[{"last_name":"Eilers","full_name":"Eilers, Anna Christina","first_name":"Anna Christina"},{"full_name":"Mackenzie, Ruari","last_name":"Mackenzie","first_name":"Ruari"},{"first_name":"Elia","last_name":"Pizzati","full_name":"Pizzati, Elia"},{"orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","full_name":"Matthee, Jorryt J","last_name":"Matthee"},{"first_name":"Joseph F.","full_name":"Hennawi, Joseph F.","last_name":"Hennawi"},{"first_name":"Haowen","full_name":"Zhang, Haowen","last_name":"Zhang"},{"first_name":"Rongmon","full_name":"Bordoloi, Rongmon","last_name":"Bordoloi"},{"first_name":"Daichi","last_name":"Kashino","full_name":"Kashino, Daichi"},{"last_name":"Lilly","full_name":"Lilly, Simon J.","first_name":"Simon J."},{"first_name":"Rohan P.","full_name":"Naidu, Rohan P.","last_name":"Naidu"},{"first_name":"Robert A.","full_name":"Simcoe, Robert A.","last_name":"Simcoe"},{"last_name":"Yue","full_name":"Yue, Minghao","first_name":"Minghao"},{"first_name":"Carlos S.","full_name":"Frenk, Carlos S.","last_name":"Frenk"},{"first_name":"John C.","last_name":"Helly","full_name":"Helly, John C."},{"full_name":"Schaller, Matthieu","last_name":"Schaller","first_name":"Matthieu"},{"full_name":"Schaye, Joop","last_name":"Schaye","first_name":"Joop"}],"file_date_updated":"2024-11-04T08:42:23Z","publication":"Astrophysical Journal","scopus_import":"1","isi":1,"intvolume":"       974","DOAJ_listed":"1","file":[{"success":1,"access_level":"open_access","relation":"main_file","file_size":1042470,"file_name":"2024_AstrophysicalJour_Eilers.pdf","creator":"dernst","date_created":"2024-11-04T08:42:23Z","file_id":"18496","date_updated":"2024-11-04T08:42:23Z","content_type":"application/pdf","checksum":"1fcac3d11d01d91cf2bb4963b6e10b22"}],"acknowledgement":"The authors would like to thank the anonymous referee for the thoughtful comments, which significantly improved our manuscript, and Jan-Torge Schindler, Jiamu Huang, and Feige Wang for helpful discussions.\r\n\r\nJ.F.H. and E.P. acknowledge support from the European Research Council (ERC) under the European Unions Horizon 2020 research and innovation program (grant agreement No. 885301). J.M. acknowledges support from the European Union (ERC, AGENTS, 101076224).\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The JWST data presented in this article were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. The specific observations analyzed are associated with program #1243 and can be accessed via doi:10.17909/m5mp-5v90.\r\n\r\nThis work used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through a Directors Discretionary Time allocation in 2023/24, under the auspices of the UKRI-funded DiRAC Federation Project. The equipment was funded by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1, Durham University and STFC operations grant ST/R000832/1. DiRAC is part of the National e-Infrastructure.\r\n\r\nWe thank the Instituto de Astrofisica de Andalucia (IAA-CSIC), Centro de Supercomputacion de Galicia (CESGA), and Spanish Academic and Research Network (RedIRIS) in Spain for hosting Uchuu DR1, DR2, and DR3 in the Skies & Universes site for cosmological simulations. The Uchuu simulations were carried out on the Aterui II supercomputer at the Center for Computational Astrophysics, CfCA, of the National Astronomical Observatory of Japan, and the K computer at the RIKEN Advanced Institute for Computational Science. The Uchuu Data Releases efforts have made use of the skunIAA_RedIRIS and skun6IAA computer facilities managed by the IAA-CSIC in Spain (MICINN EU-Feder grant EQC2018-004366-P).","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"oa":1,"article_type":"original","OA_type":"gold","doi":"10.3847/1538-4357/ad778b","OA_place":"publisher","ddc":["520"],"article_processing_charge":"Yes","citation":{"short":"A.C. Eilers, R. Mackenzie, E. Pizzati, J.J. Matthee, J.F. Hennawi, H. Zhang, R. Bordoloi, D. Kashino, S.J. Lilly, R.P. Naidu, R.A. Simcoe, M. Yue, C.S. Frenk, J.C. Helly, M. Schaller, J. Schaye, Astrophysical Journal 974 (2024).","mla":"Eilers, Anna Christina, et al. “EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” <i>Astrophysical Journal</i>, vol. 974, no. 2, 275, IOP Publishing, 2024, doi:<a href=\"https://doi.org/10.3847/1538-4357/ad778b\">10.3847/1538-4357/ad778b</a>.","ieee":"A. C. Eilers <i>et al.</i>, “EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6,” <i>Astrophysical Journal</i>, vol. 974, no. 2. IOP Publishing, 2024.","ama":"Eilers AC, Mackenzie R, Pizzati E, et al. EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. <i>Astrophysical Journal</i>. 2024;974(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/ad778b\">10.3847/1538-4357/ad778b</a>","apa":"Eilers, A. C., Mackenzie, R., Pizzati, E., Matthee, J. J., Hennawi, J. F., Zhang, H., … Schaye, J. (2024). EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. <i>Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ad778b\">https://doi.org/10.3847/1538-4357/ad778b</a>","chicago":"Eilers, Anna Christina, Ruari Mackenzie, Elia Pizzati, Jorryt J Matthee, Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, et al. “EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” <i>Astrophysical Journal</i>. IOP Publishing, 2024. <a href=\"https://doi.org/10.3847/1538-4357/ad778b\">https://doi.org/10.3847/1538-4357/ad778b</a>.","ista":"Eilers AC, Mackenzie R, Pizzati E, Matthee JJ, Hennawi JF, Zhang H, Bordoloi R, Kashino D, Lilly SJ, Naidu RP, Simcoe RA, Yue M, Frenk CS, Helly JC, Schaller M, Schaye J. 2024. EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 974(2), 275."},"_id":"18494","month":"10","title":"EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization"}],"has_accepted_license":"1","date_published":"2024-10-01T00:00:00Z","date_updated":"2025-09-08T14:29:05Z","year":"2024","oa_version":"Published Version","issue":"2","publisher":"IOP Publishing","day":"01","type":"journal_article","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"quality_controlled":"1","volume":15,"abstract":[{"lang":"eng","text":"The Golgi apparatus is essential for protein sorting, yet its quality control mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase complex uses its rhomboid pseudo-protease subunit, Dsc2, to assess the hydrophobic length of α-helical transmembrane domains (TMDs) at the Golgi. Thereby the Dsc complex likely interacts with orphaned ER and Golgi proteins that have shorter TMDs and ubiquitinates them for targeted degradation. Some Dsc substrates will be extracted by Cdc48 for endosome and Golgi associated proteasomal degradation (EGAD), while others will undergo ESCRT dependent vacuolar degradation. Some substrates are degraded by both, EGAD- or ESCRT pathways. The accumulation of Dsc substrates entails a specific increase in glycerophospholipids with shorter and asymmetric fatty acyl chains. Hence, the Dsc complex mediates the selective degradation of orphaned proteins at the sorting center of cells, which prevents their spreading across other organelles and thereby preserves cellular membrane protein and lipid composition."}],"article_number":"9257","publication_status":"published","language":[{"iso":"eng"}],"external_id":{"isi":["001345548100007"],"pmid":["39461958"]},"date_created":"2024-11-10T23:01:58Z","oa":1,"publication_identifier":{"eissn":["2041-1723"]},"acknowledgement":"We thank Snezhana Oliferenko, Hesso Farhan, Chris Dunworth, and Lukas A Huber for critically reading the manuscript, Ming Li, Peter Espenshade, Sebastien Leon, and Scott Emr for reagents, Bob Kaufmann for help in characterizing the Dsc2 L1 loop mutant. This research was funded in part by the Austrian Science Fund (FWF) (10.55776/P32161, 10.55776/P34907, 10.55776/DOC82 to DT, and 10.55776/P36187 to OS), by a Lipotype lipidomics excellence award (LEA 2019) to OS, by a Luxembourg National Research Fund (FNR): Grant #13571826 to YW, and by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 847681 (to KRL). For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.","DOAJ_listed":"1","file":[{"content_type":"application/pdf","checksum":"32c986fc3babec999c03a5c043310f40","date_updated":"2025-01-22T14:36:33Z","file_id":"18870","date_created":"2025-01-22T14:36:33Z","file_name":"2024_NatureComm_Weyer.pdf","creator":"dernst","file_size":5634494,"relation":"main_file","access_level":"open_access","success":1}],"pmid":1,"isi":1,"intvolume":"        15","scopus_import":"1","author":[{"first_name":"Yannick","full_name":"Weyer, Yannick","last_name":"Weyer"},{"first_name":"Sinead I.","full_name":"Schwabl, Sinead I.","last_name":"Schwabl"},{"last_name":"Tang","full_name":"Tang, Xuechen","first_name":"Xuechen"},{"first_name":"Astha","last_name":"Purwar","full_name":"Purwar, Astha"},{"first_name":"Konstantin","full_name":"Siegmann, Konstantin","last_name":"Siegmann"},{"last_name":"Ruepp","full_name":"Ruepp, Angela","first_name":"Angela"},{"last_name":"Dunzendorfer-Matt","full_name":"Dunzendorfer-Matt, Theresia","first_name":"Theresia"},{"full_name":"Widerin, Michael A.","last_name":"Widerin","first_name":"Michael A."},{"first_name":"Veronika","last_name":"Niedrist","full_name":"Niedrist, Veronika"},{"first_name":"Noa J.M.","full_name":"Mutsters, Noa J.M.","last_name":"Mutsters"},{"first_name":"Maria G.","full_name":"Tettamanti, Maria G.","last_name":"Tettamanti"},{"full_name":"Weys, Sabine","last_name":"Weys","first_name":"Sabine","id":"caffa136-9669-11ed-9092-ceac12ac9c05"},{"first_name":"Bettina","last_name":"Sarg","full_name":"Sarg, Bettina"},{"first_name":"Leopold","full_name":"Kremser, Leopold","last_name":"Kremser"},{"full_name":"Liedl, Klaus R.","last_name":"Liedl","first_name":"Klaus R."},{"full_name":"Schmidt, Oliver","last_name":"Schmidt","first_name":"Oliver"},{"full_name":"Teis, David","last_name":"Teis","first_name":"David"}],"file_date_updated":"2025-01-22T14:36:33Z","publication":"Nature Communications","title":"The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi","month":"12","_id":"18522","citation":{"chicago":"Weyer, Yannick, Sinead I. Schwabl, Xuechen Tang, Astha Purwar, Konstantin Siegmann, Angela Ruepp, Theresia Dunzendorfer-Matt, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at the Golgi.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-024-53676-6\">https://doi.org/10.1038/s41467-024-53676-6</a>.","ista":"Weyer Y, Schwabl SI, Tang X, Purwar A, Siegmann K, Ruepp A, Dunzendorfer-Matt T, Widerin MA, Niedrist V, Mutsters NJM, Tettamanti MG, Weys S, Sarg B, Kremser L, Liedl KR, Schmidt O, Teis D. 2024. The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications. 15, 9257.","ama":"Weyer Y, Schwabl SI, Tang X, et al. The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-024-53676-6\">10.1038/s41467-024-53676-6</a>","apa":"Weyer, Y., Schwabl, S. I., Tang, X., Purwar, A., Siegmann, K., Ruepp, A., … Teis, D. (2024). The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-024-53676-6\">https://doi.org/10.1038/s41467-024-53676-6</a>","ieee":"Y. Weyer <i>et al.</i>, “The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024.","short":"Y. Weyer, S.I. Schwabl, X. Tang, A. Purwar, K. Siegmann, A. Ruepp, T. Dunzendorfer-Matt, M.A. Widerin, V. Niedrist, N.J.M. Mutsters, M.G. Tettamanti, S. Weys, B. Sarg, L. Kremser, K.R. Liedl, O. Schmidt, D. Teis, Nature Communications 15 (2024).","mla":"Weyer, Yannick, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at the Golgi.” <i>Nature Communications</i>, vol. 15, 9257, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-024-53676-6\">10.1038/s41467-024-53676-6</a>."},"article_processing_charge":"Yes","ddc":["570"],"OA_place":"publisher","doi":"10.1038/s41467-024-53676-6","article_type":"original","OA_type":"gold","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","type":"journal_article","publisher":"Springer Nature","day":"01","year":"2024","oa_version":"Published Version","date_updated":"2026-03-05T11:20:12Z","has_accepted_license":"1","date_published":"2024-12-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"}]