---
_id: '10609'
abstract:
- lang: eng
  text: "We study Multi-party computation (MPC) in the setting of subversion, where
    the adversary tampers with the machines of honest parties. Our goal is to construct
    actively secure MPC protocols where parties are corrupted adaptively by an adversary
    (as in the standard adaptive security setting), and in addition, honest parties’
    machines are compromised.\r\nThe idea of reverse firewalls (RF) was introduced
    at EUROCRYPT’15 by Mironov and Stephens-Davidowitz as an approach to protecting
    protocols against corruption of honest parties’ devices. Intuitively, an RF for
    a party   P  is an external entity that sits between   P  and the outside world
    and whose scope is to sanitize   P ’s incoming and outgoing messages in the face
    of subversion of their computer. Mironov and Stephens-Davidowitz constructed a
    protocol for passively-secure two-party computation. At CRYPTO’20, Chakraborty,
    Dziembowski and Nielsen constructed a protocol for secure computation with firewalls
    that improved on this result, both by extending it to multi-party computation
    protocol, and considering active security in the presence of static corruptions.
    In this paper, we initiate the study of RF for MPC in the adaptive setting. We
    put forward a definition for adaptively secure MPC in the reverse firewall setting,
    explore relationships among the security notions, and then construct reverse firewalls
    for MPC in this stronger setting of adaptive security. We also resolve the open
    question of Chakraborty, Dziembowski and Nielsen by removing the need for a trusted
    setup in constructing RF for MPC. Towards this end, we construct reverse firewalls
    for adaptively secure augmented coin tossing and adaptively secure zero-knowledge
    protocols and obtain a constant round adaptively secure MPC protocol in the reverse
    firewall setting without setup. Along the way, we propose a new multi-party adaptively
    secure coin tossing protocol in the plain model, that is of independent interest."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Suvradip
  full_name: Chakraborty, Suvradip
  id: B9CD0494-D033-11E9-B219-A439E6697425
  last_name: Chakraborty
- first_name: Chaya
  full_name: Ganesh, Chaya
  last_name: Ganesh
- first_name: Mahak
  full_name: Pancholi, Mahak
  last_name: Pancholi
- first_name: Pratik
  full_name: Sarkar, Pratik
  last_name: Sarkar
citation:
  ama: 'Chakraborty S, Ganesh C, Pancholi M, Sarkar P. Reverse firewalls for adaptively
    secure MPC without setup. In: <i>27th International Conference on the Theory and
    Application of Cryptology and Information Security</i>. Vol 13091. Springer Nature;
    2021:335-364. doi:<a href="https://doi.org/10.1007/978-3-030-92075-3_12">10.1007/978-3-030-92075-3_12</a>'
  apa: 'Chakraborty, S., Ganesh, C., Pancholi, M., &#38; Sarkar, P. (2021). Reverse
    firewalls for adaptively secure MPC without setup. In <i>27th International Conference
    on the Theory and Application of Cryptology and Information Security</i> (Vol.
    13091, pp. 335–364). Virtual, Singapore: Springer Nature. <a href="https://doi.org/10.1007/978-3-030-92075-3_12">https://doi.org/10.1007/978-3-030-92075-3_12</a>'
  chicago: Chakraborty, Suvradip, Chaya Ganesh, Mahak Pancholi, and Pratik Sarkar.
    “Reverse Firewalls for Adaptively Secure MPC without Setup.” In <i>27th International
    Conference on the Theory and Application of Cryptology and Information Security</i>,
    13091:335–64. Springer Nature, 2021. <a href="https://doi.org/10.1007/978-3-030-92075-3_12">https://doi.org/10.1007/978-3-030-92075-3_12</a>.
  ieee: S. Chakraborty, C. Ganesh, M. Pancholi, and P. Sarkar, “Reverse firewalls
    for adaptively secure MPC without setup,” in <i>27th International Conference
    on the Theory and Application of Cryptology and Information Security</i>, Virtual,
    Singapore, 2021, vol. 13091, pp. 335–364.
  ista: 'Chakraborty S, Ganesh C, Pancholi M, Sarkar P. 2021. Reverse firewalls for
    adaptively secure MPC without setup. 27th International Conference on the Theory
    and Application of Cryptology and Information Security. ASIACRYPT: International
    Conference on Cryptology in Asia, LNCS, vol. 13091, 335–364.'
  mla: Chakraborty, Suvradip, et al. “Reverse Firewalls for Adaptively Secure MPC
    without Setup.” <i>27th International Conference on the Theory and Application
    of Cryptology and Information Security</i>, vol. 13091, Springer Nature, 2021,
    pp. 335–64, doi:<a href="https://doi.org/10.1007/978-3-030-92075-3_12">10.1007/978-3-030-92075-3_12</a>.
  short: S. Chakraborty, C. Ganesh, M. Pancholi, P. Sarkar, in:, 27th International
    Conference on the Theory and Application of Cryptology and Information Security,
    Springer Nature, 2021, pp. 335–364.
conference:
  end_date: 2021-12-10
  location: Virtual, Singapore
  name: 'ASIACRYPT: International Conference on Cryptology in Asia'
  start_date: 2021-12-06
date_created: 2022-01-09T23:01:27Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2025-04-14T07:22:06Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/978-3-030-92075-3_12
ec_funded: 1
external_id:
  isi:
  - '000927876200012'
intvolume: '     13091'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2021/1262
month: '12'
oa: 1
oa_version: Preprint
page: 335-364
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication: 27th International Conference on the Theory and Application of Cryptology
  and Information Security
publication_identifier:
  eisbn:
  - 978-3-030-92075-3
  eissn:
  - 1611-3349
  isbn:
  - 978-3-030-92074-6
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Reverse firewalls for adaptively secure MPC without setup
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 13091
year: '2021'
...
---
_id: '10617'
abstract:
- lang: eng
  text: When a flat band is partially filled with electrons, strong Coulomb interactions
    between them may lead to the emergence of topological gapped states with quantized
    Hall conductivity. Such emergent topological states have been found in partially
    filled Landau levels1 and Hofstadter bands2,3; however, in both cases, a large
    magnetic field is required to produce the underlying flat band. The recent observation
    of quantum anomalous Hall effects in narrow-band moiré materials4,5,6,7 has led
    to the theoretical prediction that such phases could be realized at zero magnetic
    field8,9,10,11,12. Here we report the observation of insulators with Chern number
    C = 1 in the zero-magnetic-field limit at half-integer filling of the moiré superlattice
    unit cell in twisted monolayer–bilayer graphene7,13,14,15. Chern insulators in
    a half-filled band suggest the spontaneous doubling of the superlattice unit cell2,3,16,
    and our calculations find a ground state of the topological charge density wave
    at half-filling of the underlying band. The discovery of these topological phases
    at fractional superlattice filling enables the further pursuit of zero-magnetic-field
    phases that have fractional statistics that exist either as elementary excitations
    or bound to lattice dislocations.
acknowledgement: We are grateful to J. Zhu for fruitful discussions. A.F.Y. acknowledges
  support from the Office of Naval Research under award N00014-20-1-2609, and the
  Gordon and Betty Moore Foundation under award GBMF9471. M.P.Z. acknowledges support
  from the ARO under MURI W911NF-16-1-0361. K.W. and T.T. acknowledge support from
  the Elemental Strategy Initiative conducted by the MEXT, Japan, via grant no. JPMXP0112101001;
  JSPS KAKENHI grant no. JP20H00354; and the CREST(JPMJCR15F3), JST. A.V. was supported
  by a Simons Investigator Award. P.L. was supported by the Department of Defense
  (DoD) through the National Defense Science and Engineering Graduate Fellowship (NDSEG)
  Program.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Y.
  full_name: Zhang, Y.
  last_name: Zhang
- first_name: M. A.
  full_name: Kumar, M. A.
  last_name: Kumar
- first_name: T.
  full_name: Soejima, T.
  last_name: Soejima
- first_name: P.
  full_name: Ledwith, P.
  last_name: Ledwith
- first_name: K.
  full_name: Watanabe, K.
  last_name: Watanabe
- first_name: T.
  full_name: Taniguchi, T.
  last_name: Taniguchi
- first_name: A.
  full_name: Vishwanath, A.
  last_name: Vishwanath
- first_name: M. P.
  full_name: Zaletel, M. P.
  last_name: Zaletel
- first_name: A. F.
  full_name: Young, A. F.
  last_name: Young
citation:
  ama: Polshyn H, Zhang Y, Kumar MA, et al. Topological charge density waves at half-integer
    filling of a moiré superlattice. <i>Nature Physics</i>. 2021. doi:<a href="https://doi.org/10.1038/s41567-021-01418-6">10.1038/s41567-021-01418-6</a>
  apa: Polshyn, H., Zhang, Y., Kumar, M. A., Soejima, T., Ledwith, P., Watanabe, K.,
    … Young, A. F. (2021). Topological charge density waves at half-integer filling
    of a moiré superlattice. <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-021-01418-6">https://doi.org/10.1038/s41567-021-01418-6</a>
  chicago: Polshyn, Hryhoriy, Y. Zhang, M. A. Kumar, T. Soejima, P. Ledwith, K. Watanabe,
    T. Taniguchi, A. Vishwanath, M. P. Zaletel, and A. F. Young. “Topological Charge
    Density Waves at Half-Integer Filling of a Moiré Superlattice.” <i>Nature Physics</i>.
    Springer Nature, 2021. <a href="https://doi.org/10.1038/s41567-021-01418-6">https://doi.org/10.1038/s41567-021-01418-6</a>.
  ieee: H. Polshyn <i>et al.</i>, “Topological charge density waves at half-integer
    filling of a moiré superlattice,” <i>Nature Physics</i>. Springer Nature, 2021.
  ista: Polshyn H, Zhang Y, Kumar MA, Soejima T, Ledwith P, Watanabe K, Taniguchi
    T, Vishwanath A, Zaletel MP, Young AF. 2021. Topological charge density waves
    at half-integer filling of a moiré superlattice. Nature Physics.
  mla: Polshyn, Hryhoriy, et al. “Topological Charge Density Waves at Half-Integer
    Filling of a Moiré Superlattice.” <i>Nature Physics</i>, Springer Nature, 2021,
    doi:<a href="https://doi.org/10.1038/s41567-021-01418-6">10.1038/s41567-021-01418-6</a>.
  short: H. Polshyn, Y. Zhang, M.A. Kumar, T. Soejima, P. Ledwith, K. Watanabe, T.
    Taniguchi, A. Vishwanath, M.P. Zaletel, A.F. Young, Nature Physics (2021).
date_created: 2022-01-13T12:30:47Z
date_published: 2021-12-09T00:00:00Z
date_updated: 2022-01-13T14:11:31Z
day: '09'
doi: 10.1038/s41567-021-01418-6
extern: '1'
external_id:
  arxiv:
  - '2104.01178'
keyword:
- general physics
- astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2104.01178
month: '12'
oa: 1
oa_version: Preprint
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Topological charge density waves at half-integer filling of a moiré superlattice
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2021'
...
---
_id: '10655'
abstract:
- lang: eng
  text: "Adeno-associated viruses (AAVs) are widely used to deliver genetic material
    in vivo to distinct cell types such as neurons or glial cells, allowing for targeted
    manipulation. Transduction of microglia is mostly excluded from this strategy,
    likely due to the cells’ heterogeneous state upon environmental changes, which
    makes AAV design challenging. Here, we established the retina as a model system
    for microglial AAV validation and optimization. First, we show that AAV2/6 transduced
    microglia in both synaptic layers, where layer preference corresponds to the intravitreal
    or subretinal delivery method. Surprisingly, we observed significantly enhanced
    microglial transduction during photoreceptor degeneration. Thus, we modified the
    AAV6 capsid to reduce heparin binding by introducing four point mutations (K531E,
    R576Q, K493S, and K459S), resulting in increased microglial transduction in the
    outer plexiform layer. Finally, to improve microglial-specific transduction, we
    validated a Cre-dependent transgene delivery cassette for use in combination with
    the Cx3cr1CreERT2 mouse line. Together, our results provide a foundation for future
    studies optimizing AAV-mediated microglia transduction and highlight that environmental
    conditions influence microglial transduction efficiency.\r\n"
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
acknowledgement: This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (grant agreement no. 715571). The research was supported by the Scientific Service
  Units (SSU) of IST Austria through resources provided by the Bioimaging Facility,
  the Life Science Facility, and the Pre-Clinical Facility, namely Sonja Haslinger
  and Michael Schunn for their animal colony management and support. We would also
  like to thank Chakrabarty Lab for sharing the plasmids for AAV2/6 production. Finally,
  we would like to thank the Siegert team members for discussion about the manuscript.
article_processing_charge: Yes
article_type: original
author:
- first_name: Margaret E
  full_name: Maes, Margaret E
  id: 3838F452-F248-11E8-B48F-1D18A9856A87
  last_name: Maes
  orcid: 0000-0001-9642-1085
- first_name: Gabriele M.
  full_name: Wögenstein, Gabriele M.
  last_name: Wögenstein
- first_name: Gloria
  full_name: Colombo, Gloria
  id: 3483CF6C-F248-11E8-B48F-1D18A9856A87
  last_name: Colombo
  orcid: 0000-0001-9434-8902
- first_name: Raquel
  full_name: Casado Polanco, Raquel
  id: 15240fc1-dbcd-11ea-9d1d-ac5a786425fd
  last_name: Casado Polanco
  orcid: 0000-0001-8293-4568
- first_name: Sandra
  full_name: Siegert, Sandra
  id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
  last_name: Siegert
  orcid: 0000-0001-8635-0877
citation:
  ama: Maes ME, Wögenstein GM, Colombo G, Casado Polanco R, Siegert S. Optimizing
    AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor
    degenerative environment. <i>Molecular Therapy - Methods and Clinical Development</i>.
    2021;23:210-224. doi:<a href="https://doi.org/10.1016/j.omtm.2021.09.006">10.1016/j.omtm.2021.09.006</a>
  apa: Maes, M. E., Wögenstein, G. M., Colombo, G., Casado Polanco, R., &#38; Siegert,
    S. (2021). Optimizing AAV2/6 microglial targeting identified enhanced efficiency
    in the photoreceptor degenerative environment. <i>Molecular Therapy - Methods
    and Clinical Development</i>. Elsevier. <a href="https://doi.org/10.1016/j.omtm.2021.09.006">https://doi.org/10.1016/j.omtm.2021.09.006</a>
  chicago: Maes, Margaret E, Gabriele M. Wögenstein, Gloria Colombo, Raquel Casado
    Polanco, and Sandra Siegert. “Optimizing AAV2/6 Microglial Targeting Identified
    Enhanced Efficiency in the Photoreceptor Degenerative Environment.” <i>Molecular
    Therapy - Methods and Clinical Development</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.omtm.2021.09.006">https://doi.org/10.1016/j.omtm.2021.09.006</a>.
  ieee: M. E. Maes, G. M. Wögenstein, G. Colombo, R. Casado Polanco, and S. Siegert,
    “Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the
    photoreceptor degenerative environment,” <i>Molecular Therapy - Methods and Clinical
    Development</i>, vol. 23. Elsevier, pp. 210–224, 2021.
  ista: Maes ME, Wögenstein GM, Colombo G, Casado Polanco R, Siegert S. 2021. Optimizing
    AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor
    degenerative environment. Molecular Therapy - Methods and Clinical Development.
    23, 210–224.
  mla: Maes, Margaret E., et al. “Optimizing AAV2/6 Microglial Targeting Identified
    Enhanced Efficiency in the Photoreceptor Degenerative Environment.” <i>Molecular
    Therapy - Methods and Clinical Development</i>, vol. 23, Elsevier, 2021, pp. 210–24,
    doi:<a href="https://doi.org/10.1016/j.omtm.2021.09.006">10.1016/j.omtm.2021.09.006</a>.
  short: M.E. Maes, G.M. Wögenstein, G. Colombo, R. Casado Polanco, S. Siegert, Molecular
    Therapy - Methods and Clinical Development 23 (2021) 210–224.
corr_author: '1'
date_created: 2022-01-23T23:01:28Z
date_published: 2021-12-10T00:00:00Z
date_updated: 2025-04-14T07:41:46Z
day: '10'
ddc:
- '570'
department:
- _id: SaSi
- _id: SiHi
doi: 10.1016/j.omtm.2021.09.006
ec_funded: 1
external_id:
  isi:
  - '000748748500019'
file:
- access_level: open_access
  checksum: 77dc540e8011c5475031bdf6ccef20a6
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-01-24T07:43:09Z
  date_updated: 2022-01-24T07:43:09Z
  file_id: '10657'
  file_name: 2021_MolTherMethodsClinDev_Maes.pdf
  file_size: 4794147
  relation: main_file
  success: 1
file_date_updated: 2022-01-24T07:43:09Z
has_accepted_license: '1'
intvolume: '        23'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 210-224
project:
- _id: 25D4A630-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '715571'
  name: Microglia action towards neuronal circuit formation and function in health
    and disease
publication: Molecular Therapy - Methods and Clinical Development
publication_identifier:
  eissn:
  - 2329-0501
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the
  photoreceptor degenerative environment
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2021'
...
---
_id: '10688'
abstract:
- lang: eng
  text: "Civl is a static verifier for concurrent programs designed around the conceptual
    framework of layered refinement,\r\nwhich views the task of verifying a program
    as a sequence of program simplification steps each justified by its own invariant.
    Civl verifies a layered concurrent program that compactly expresses all the programs
    in this sequence and the supporting invariants. This paper presents the design
    and implementation of the Civl verifier."
acknowledgement: This research was performed while Bernhard Kragl was at IST Austria,
  supported in part by the Austrian Science Fund (FWF) under grant Z211-N23 (Wittgenstein
  Award).
alternative_title:
- Conference Series
article_processing_charge: No
author:
- first_name: Bernhard
  full_name: Kragl, Bernhard
  id: 320FC952-F248-11E8-B48F-1D18A9856A87
  last_name: Kragl
  orcid: 0000-0001-7745-9117
- first_name: Shaz
  full_name: Qadeer, Shaz
  last_name: Qadeer
citation:
  ama: 'Kragl B, Qadeer S. The Civl verifier. In: Ruzica P, Whalen MW, eds. <i>Proceedings
    of the 21st Conference on Formal Methods in Computer-Aided Design</i>. Vol 2.
    TU Wien Academic Press; 2021:143–152. doi:<a href="https://doi.org/10.34727/2021/isbn.978-3-85448-046-4_23">10.34727/2021/isbn.978-3-85448-046-4_23</a>'
  apa: 'Kragl, B., &#38; Qadeer, S. (2021). The Civl verifier. In P. Ruzica &#38;
    M. W. Whalen (Eds.), <i>Proceedings of the 21st Conference on Formal Methods in
    Computer-Aided Design</i> (Vol. 2, pp. 143–152). Virtual: TU Wien Academic Press.
    <a href="https://doi.org/10.34727/2021/isbn.978-3-85448-046-4_23">https://doi.org/10.34727/2021/isbn.978-3-85448-046-4_23</a>'
  chicago: Kragl, Bernhard, and Shaz Qadeer. “The Civl Verifier.” In <i>Proceedings
    of the 21st Conference on Formal Methods in Computer-Aided Design</i>, edited
    by Piskac Ruzica and Michael W. Whalen, 2:143–152. TU Wien Academic Press, 2021.
    <a href="https://doi.org/10.34727/2021/isbn.978-3-85448-046-4_23">https://doi.org/10.34727/2021/isbn.978-3-85448-046-4_23</a>.
  ieee: B. Kragl and S. Qadeer, “The Civl verifier,” in <i>Proceedings of the 21st
    Conference on Formal Methods in Computer-Aided Design</i>, Virtual, 2021, vol.
    2, pp. 143–152.
  ista: 'Kragl B, Qadeer S. 2021. The Civl verifier. Proceedings of the 21st Conference
    on Formal Methods in Computer-Aided Design. FMCAD: Formal Methods in Computer-Aided
    Design, Conference Series, vol. 2, 143–152.'
  mla: Kragl, Bernhard, and Shaz Qadeer. “The Civl Verifier.” <i>Proceedings of the
    21st Conference on Formal Methods in Computer-Aided Design</i>, edited by Piskac
    Ruzica and Michael W. Whalen, vol. 2, TU Wien Academic Press, 2021, pp. 143–152,
    doi:<a href="https://doi.org/10.34727/2021/isbn.978-3-85448-046-4_23">10.34727/2021/isbn.978-3-85448-046-4_23</a>.
  short: B. Kragl, S. Qadeer, in:, P. Ruzica, M.W. Whalen (Eds.), Proceedings of the
    21st Conference on Formal Methods in Computer-Aided Design, TU Wien Academic Press,
    2021, pp. 143–152.
conference:
  end_date: 2021-10-22
  location: Virtual
  name: 'FMCAD: Formal Methods in Computer-Aided Design'
  start_date: 2021-10-20
corr_author: '1'
date_created: 2022-01-26T08:01:30Z
date_published: 2021-10-01T00:00:00Z
date_updated: 2025-04-15T06:25:56Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.34727/2021/isbn.978-3-85448-046-4_23
editor:
- first_name: Piskac
  full_name: Ruzica, Piskac
  last_name: Ruzica
- first_name: Michael W.
  full_name: Whalen, Michael W.
  last_name: Whalen
file:
- access_level: open_access
  checksum: 35438ac9f9750340b7f8ae4ae3220d9f
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-01-26T08:04:29Z
  date_updated: 2022-01-26T08:04:29Z
  file_id: '10689'
  file_name: 2021_FCAD2021_Kragl.pdf
  file_size: 390555
  relation: main_file
  success: 1
file_date_updated: 2022-01-26T08:04:29Z
has_accepted_license: '1'
intvolume: '         2'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 143–152
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: Formal methods for the design and analysis of complex systems
publication: Proceedings of the 21st Conference on Formal Methods in Computer-Aided
  Design
publication_identifier:
  isbn:
  - 978-3-85448-046-4
publication_status: published
publisher: TU Wien Academic Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Civl verifier
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 2
year: '2021'
...
---
_id: '10002'
abstract:
- lang: eng
  text: 'We present a faster symbolic algorithm for the following central problem
    in probabilistic verification: Compute the maximal end-component (MEC) decomposition
    of Markov decision processes (MDPs). This problem generalizes the SCC decomposition
    problem of graphs and closed recurrent sets of Markov chains. The model of symbolic
    algorithms is widely used in formal verification and model-checking, where access
    to the input model is restricted to only symbolic operations (e.g., basic set
    operations and computation of one-step neighborhood). For an input MDP with  n  vertices
    and  m  edges, the classical symbolic algorithm from the 1990s for the MEC decomposition
    requires  O(n2)  symbolic operations and  O(1)  symbolic space. The only other
    symbolic algorithm for the MEC decomposition requires  O(nm−−√)  symbolic operations
    and  O(m−−√)  symbolic space. A main open question is whether the worst-case  O(n2)  bound
    for symbolic operations can be beaten. We present a symbolic algorithm that requires  O˜(n1.5)  symbolic
    operations and  O˜(n−−√)  symbolic space. Moreover, the parametrization of our
    algorithm provides a trade-off between symbolic operations and symbolic space:
    for all  0<ϵ≤1/2  the symbolic algorithm requires  O˜(n2−ϵ)  symbolic operations
    and  O˜(nϵ)  symbolic space ( O˜  hides poly-logarithmic factors). Using our techniques
    we present faster algorithms for computing the almost-sure winning regions of  ω
    -regular objectives for MDPs. We consider the canonical parity objectives for  ω
    -regular objectives, and for parity objectives with  d -priorities we present
    an algorithm that computes the almost-sure winning region with  O˜(n2−ϵ)  symbolic
    operations and  O˜(nϵ)  symbolic space, for all  0<ϵ≤1/2 .'
acknowledgement: The authors are grateful to the anonymous referees for their valuable
  comments. A. S. is fully supported by the Vienna Science and Technology Fund (WWTF)
  through project ICT15–003. K. C. is supported by the Austrian Science Fund (FWF)
  NFN Grant No S11407-N23 (RiSE/SHiNE) and by the ERC CoG 863818 (ForM-SMArt). For
  M. H. the research leading to these results has received funding from the European
  Research Council under the European Unions Seventh Framework Programme (FP/2007–2013)
  / ERC Grant Agreement no. 340506.
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Wolfgang
  full_name: Dvorak, Wolfgang
  last_name: Dvorak
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Alexander
  full_name: Svozil, Alexander
  last_name: Svozil
citation:
  ama: 'Chatterjee K, Dvorak W, Henzinger M, Svozil A. Symbolic time and space tradeoffs
    for probabilistic verification. In: <i>Proceedings of the 36th Annual ACM/IEEE
    Symposium on Logic in Computer Science</i>. Institute of Electrical and Electronics
    Engineers; 2021:1-13. doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470739">10.1109/LICS52264.2021.9470739</a>'
  apa: 'Chatterjee, K., Dvorak, W., Henzinger, M., &#38; Svozil, A. (2021). Symbolic
    time and space tradeoffs for probabilistic verification. In <i>Proceedings of
    the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i> (pp. 1–13).
    Rome, Italy: Institute of Electrical and Electronics Engineers. <a href="https://doi.org/10.1109/LICS52264.2021.9470739">https://doi.org/10.1109/LICS52264.2021.9470739</a>'
  chicago: Chatterjee, Krishnendu, Wolfgang Dvorak, Monika Henzinger, and Alexander
    Svozil. “Symbolic Time and Space Tradeoffs for Probabilistic Verification.” In
    <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i>,
    1–13. Institute of Electrical and Electronics Engineers, 2021. <a href="https://doi.org/10.1109/LICS52264.2021.9470739">https://doi.org/10.1109/LICS52264.2021.9470739</a>.
  ieee: K. Chatterjee, W. Dvorak, M. Henzinger, and A. Svozil, “Symbolic time and
    space tradeoffs for probabilistic verification,” in <i>Proceedings of the 36th
    Annual ACM/IEEE Symposium on Logic in Computer Science</i>, Rome, Italy, 2021,
    pp. 1–13.
  ista: 'Chatterjee K, Dvorak W, Henzinger M, Svozil A. 2021. Symbolic time and space
    tradeoffs for probabilistic verification. Proceedings of the 36th Annual ACM/IEEE
    Symposium on Logic in Computer Science. LICS: Logic in Computer Science, 1–13.'
  mla: Chatterjee, Krishnendu, et al. “Symbolic Time and Space Tradeoffs for Probabilistic
    Verification.” <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in
    Computer Science</i>, Institute of Electrical and Electronics Engineers, 2021,
    pp. 1–13, doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470739">10.1109/LICS52264.2021.9470739</a>.
  short: K. Chatterjee, W. Dvorak, M. Henzinger, A. Svozil, in:, Proceedings of the
    36th Annual ACM/IEEE Symposium on Logic in Computer Science, Institute of Electrical
    and Electronics Engineers, 2021, pp. 1–13.
conference:
  end_date: 2021-07-02
  location: Rome, Italy
  name: 'LICS: Logic in Computer Science'
  start_date: 2021-06-29
date_created: 2021-09-12T22:01:24Z
date_published: 2021-07-07T00:00:00Z
date_updated: 2025-07-10T11:15:45Z
day: '07'
department:
- _id: KrCh
doi: 10.1109/LICS52264.2021.9470739
ec_funded: 1
external_id:
  arxiv:
  - '2104.07466'
  isi:
  - '000947350400089'
isi: 1
keyword:
- Computer science
- Computational modeling
- Markov processes
- Probabilistic logic
- Formal verification
- Game Theory
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2104.07466
month: '07'
oa: 1
oa_version: Preprint
page: 1-13
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer
  Science
publication_identifier:
  eisbn:
  - 978-1-6654-4895-6
  isbn:
  - 978-1-6654-4896-3
  issn:
  - 1043-6871
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Symbolic time and space tradeoffs for probabilistic verification
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10004'
abstract:
- lang: eng
  text: 'Markov chains are the de facto finite-state model for stochastic dynamical
    systems, and Markov decision processes (MDPs) extend Markov chains by incorporating
    non-deterministic behaviors. Given an MDP and rewards on states, a classical optimization
    criterion is the maximal expected total reward where the MDP stops after T steps,
    which can be computed by a simple dynamic programming algorithm. We consider a
    natural generalization of the problem where the stopping times can be chosen according
    to a probability distribution, such that the expected stopping time is T, to optimize
    the expected total reward. Quite surprisingly we establish inter-reducibility
    of the expected stopping-time problem for Markov chains with the Positivity problem
    (which is related to the well-known Skolem problem), for which establishing either
    decidability or undecidability would be a major breakthrough. Given the hardness
    of the exact problem, we consider the approximate version of the problem: we show
    that it can be solved in exponential time for Markov chains and in exponential
    space for MDPs.'
acknowledgement: We are grateful to the anonymous reviewers of LICS 2021 and of a
  previous version of this paper for insightful comments that helped improving the
  presentation. This research was partially supported by the grant ERC CoG 863818
  (ForM-SMArt).
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Laurent
  full_name: Doyen, Laurent
  last_name: Doyen
citation:
  ama: 'Chatterjee K, Doyen L. Stochastic processes with expected stopping time. In:
    <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i>.
    Institute of Electrical and Electronics Engineers; 2021:1-13. doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470595">10.1109/LICS52264.2021.9470595</a>'
  apa: 'Chatterjee, K., &#38; Doyen, L. (2021). Stochastic processes with expected
    stopping time. In <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic
    in Computer Science</i> (pp. 1–13). Rome, Italy: Institute of Electrical and Electronics
    Engineers. <a href="https://doi.org/10.1109/LICS52264.2021.9470595">https://doi.org/10.1109/LICS52264.2021.9470595</a>'
  chicago: Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected
    Stopping Time.” In <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic
    in Computer Science</i>, 1–13. Institute of Electrical and Electronics Engineers,
    2021. <a href="https://doi.org/10.1109/LICS52264.2021.9470595">https://doi.org/10.1109/LICS52264.2021.9470595</a>.
  ieee: K. Chatterjee and L. Doyen, “Stochastic processes with expected stopping time,”
    in <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i>,
    Rome, Italy, 2021, pp. 1–13.
  ista: 'Chatterjee K, Doyen L. 2021. Stochastic processes with expected stopping
    time. Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science.
    LICS: Logic in Computer Science, 1–13.'
  mla: Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected
    Stopping Time.” <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic
    in Computer Science</i>, Institute of Electrical and Electronics Engineers, 2021,
    pp. 1–13, doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470595">10.1109/LICS52264.2021.9470595</a>.
  short: K. Chatterjee, L. Doyen, in:, Proceedings of the 36th Annual ACM/IEEE Symposium
    on Logic in Computer Science, Institute of Electrical and Electronics Engineers,
    2021, pp. 1–13.
conference:
  end_date: 2021-07-02
  location: Rome, Italy
  name: 'LICS: Logic in Computer Science'
  start_date: 2021-06-29
date_created: 2021-09-12T22:01:25Z
date_published: 2021-07-07T00:00:00Z
date_updated: 2025-09-08T14:54:13Z
day: '07'
department:
- _id: KrCh
doi: 10.1109/LICS52264.2021.9470595
ec_funded: 1
external_id:
  arxiv:
  - '2104.07278'
  isi:
  - '000947350400036'
isi: 1
keyword:
- Computer science
- Heuristic algorithms
- Memory management
- Automata
- Markov processes
- Probability distribution
- Complexity theory
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2104.07278
month: '07'
oa: 1
oa_version: Preprint
page: 1-13
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer
  Science
publication_identifier:
  eisbn:
  - 978-1-6654-4895-6
  isbn:
  - 978-1-6654-4896-3
  issn:
  - 1043-6871
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
related_material:
  record:
  - id: '18630'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Stochastic processes with expected stopping time
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10223'
abstract:
- lang: eng
  text: Growth regulation tailors development in plants to their environment. A prominent
    example of this is the response to gravity, in which shoots bend up and roots
    bend down1. This paradox is based on opposite effects of the phytohormone auxin,
    which promotes cell expansion in shoots while inhibiting it in roots via a yet
    unknown cellular mechanism2. Here, by combining microfluidics, live imaging, genetic
    engineering and phosphoproteomics in Arabidopsis thaliana, we advance understanding
    of how auxin inhibits root growth. We show that auxin activates two distinct,
    antagonistically acting signalling pathways that converge on rapid regulation
    of apoplastic pH, a causative determinant of growth. Cell surface-based TRANSMEMBRANE
    KINASE1 (TMK1) interacts with and mediates phosphorylation and activation of plasma
    membrane H+-ATPases for apoplast acidification, while intracellular canonical
    auxin signalling promotes net cellular H+ influx, causing apoplast alkalinization.
    Simultaneous activation of these two counteracting mechanisms poises roots for
    rapid, fine-tuned growth modulation in navigating complex soil environments.
acknowledged_ssus:
- _id: LifeSc
- _id: M-Shop
- _id: Bio
acknowledgement: We thank N. Gnyliukh and L. Hörmayer for technical assistance and
  N. Paris for sharing PM-Cyto seeds. We gratefully acknowledge the Life Science,
  Machine Shop and Bioimaging Facilities of IST Austria. This project has received
  funding from the European Research Council Advanced Grant (ETAP-742985) and the
  Austrian Science Fund (FWF) under I 3630-B25 to J.F., the National Institutes of
  Health (GM067203) to W.M.G., the Netherlands Organization for Scientific Research
  (NWO; VIDI-864.13.001), Research Foundation-Flanders (FWO; Odysseus II G0D0515N)
  and a European Research Council Starting Grant (TORPEDO-714055) to W.S. and B.D.R.,
  the VICI grant (865.14.001) from the Netherlands Organization for Scientific Research
  to M.R. and D.W., the Australian Research Council and China National Distinguished
  Expert Project (WQ20174400441) to S.S., the MEXT/JSPS KAKENHI to K.T. (20K06685)
  and T.K. (20H05687 and 20H05910), the European Union’s Horizon 2020 research and
  innovation programme under Marie Skłodowska-Curie grant agreement no. 665385 and
  the DOC Fellowship of the Austrian Academy of Sciences to L.L., and the China Scholarship
  Council to J.C.
article_processing_charge: No
article_type: original
author:
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Inge
  full_name: Verstraeten, Inge
  id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
  last_name: Verstraeten
  orcid: 0000-0001-7241-2328
- first_name: Mark
  full_name: Roosjen, Mark
  last_name: Roosjen
- first_name: Koji
  full_name: Takahashi, Koji
  last_name: Takahashi
- first_name: Lesia
  full_name: Rodriguez Solovey, Lesia
  id: 3922B506-F248-11E8-B48F-1D18A9856A87
  last_name: Rodriguez Solovey
  orcid: 0000-0002-7244-7237
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Jian
  full_name: Chen, Jian
  last_name: Chen
- first_name: Lana
  full_name: Shabala, Lana
  last_name: Shabala
- first_name: Wouter
  full_name: Smet, Wouter
  last_name: Smet
- first_name: Hong
  full_name: Ren, Hong
  last_name: Ren
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
- first_name: Sergey
  full_name: Shabala, Sergey
  last_name: Shabala
- first_name: Bert
  full_name: De Rybel, Bert
  last_name: De Rybel
- first_name: Dolf
  full_name: Weijers, Dolf
  last_name: Weijers
- first_name: Toshinori
  full_name: Kinoshita, Toshinori
  last_name: Kinoshita
- first_name: William M.
  full_name: Gray, William M.
  last_name: Gray
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Li L, Verstraeten I, Roosjen M, et al. Cell surface and intracellular auxin
    signalling for H<sup>+</sup> fluxes in root growth. <i>Nature</i>. 2021;599(7884):273-277.
    doi:<a href="https://doi.org/10.1038/s41586-021-04037-6">10.1038/s41586-021-04037-6</a>
  apa: Li, L., Verstraeten, I., Roosjen, M., Takahashi, K., Rodriguez Solovey, L.,
    Merrin, J., … Friml, J. (2021). Cell surface and intracellular auxin signalling
    for H<sup>+</sup> fluxes in root growth. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/s41586-021-04037-6">https://doi.org/10.1038/s41586-021-04037-6</a>
  chicago: Li, Lanxin, Inge Verstraeten, Mark Roosjen, Koji Takahashi, Lesia Rodriguez
    Solovey, Jack Merrin, Jian Chen, et al. “Cell Surface and Intracellular Auxin
    Signalling for H<sup>+</sup> Fluxes in Root Growth.” <i>Nature</i>. Springer Nature,
    2021. <a href="https://doi.org/10.1038/s41586-021-04037-6">https://doi.org/10.1038/s41586-021-04037-6</a>.
  ieee: L. Li <i>et al.</i>, “Cell surface and intracellular auxin signalling for
    H<sup>+</sup> fluxes in root growth,” <i>Nature</i>, vol. 599, no. 7884. Springer
    Nature, pp. 273–277, 2021.
  ista: Li L, Verstraeten I, Roosjen M, Takahashi K, Rodriguez Solovey L, Merrin J,
    Chen J, Shabala L, Smet W, Ren H, Vanneste S, Shabala S, De Rybel B, Weijers D,
    Kinoshita T, Gray WM, Friml J. 2021. Cell surface and intracellular auxin signalling
    for H<sup>+</sup> fluxes in root growth. Nature. 599(7884), 273–277.
  mla: Li, Lanxin, et al. “Cell Surface and Intracellular Auxin Signalling for H<sup>+</sup>
    Fluxes in Root Growth.” <i>Nature</i>, vol. 599, no. 7884, Springer Nature, 2021,
    pp. 273–77, doi:<a href="https://doi.org/10.1038/s41586-021-04037-6">10.1038/s41586-021-04037-6</a>.
  short: L. Li, I. Verstraeten, M. Roosjen, K. Takahashi, L. Rodriguez Solovey, J.
    Merrin, J. Chen, L. Shabala, W. Smet, H. Ren, S. Vanneste, S. Shabala, B. De Rybel,
    D. Weijers, T. Kinoshita, W.M. Gray, J. Friml, Nature 599 (2021) 273–277.
corr_author: '1'
date_created: 2021-11-07T23:01:25Z
date_published: 2021-11-11T00:00:00Z
date_updated: 2025-07-10T11:49:46Z
day: '11'
department:
- _id: JiFr
- _id: NanoFab
doi: 10.1038/s41586-021-04037-6
ec_funded: 1
external_id:
  isi:
  - '000713338100006'
  pmid:
  - '34707283'
intvolume: '       599'
isi: 1
issue: '7884'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.doi.org/10.21203/rs.3.rs-266395/v3
month: '11'
oa: 1
oa_version: Preprint
page: 273-277
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 26B4D67E-B435-11E9-9278-68D0E5697425
  grant_number: '25351'
  name: 'A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated
    Rapid Growth Inhibition in Arabidopsis Root'
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Webpage
    relation: press_release
    url: https://ist.ac.at/en/news/stop-and-grow/
  record:
  - id: '10095'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Cell surface and intracellular auxin signalling for H<sup>+</sup> fluxes in
  root growth
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 599
year: '2021'
...
---
_id: '10280'
abstract:
- lang: eng
  text: 'Machines enabled the Industrial Revolution and are central to modern technological
    progress: A machine’s parts transmit forces, motion, and energy to one another
    in a predetermined manner. Today’s engineering frontier, building artificial micromachines
    that emulate the biological machinery of living organisms, requires faithful assembly
    and energy consumption at the microscale. Here, we demonstrate the programmable
    assembly of active particles into autonomous metamachines using optical templates.
    Metamachines, or machines made of machines, are stable, mobile and autonomous
    architectures, whose dynamics stems from the geometry. We use the interplay between
    anisotropic force generation of the active colloids with the control of their
    orientation by local geometry. This allows autonomous reprogramming of active
    particles of the metamachines to achieve multiple functions. It permits the modular
    assembly of metamachines by fusion, reconfiguration of metamachines and, we anticipate,
    a shift in focus of self-assembly towards active matter and reprogrammable materials.'
acknowledgement: The authors thank R. Jazzar for useful advice regarding the synthesis
  of heterodimers. We thank S. Sacanna for critical reading. This material is based
  upon work supported by the National Science Foundation under Grant No. DMR-1554724
  and Department of Army Research under grant W911NF-20-1-0112.
article_number: '6398'
article_processing_charge: Yes
article_type: original
author:
- first_name: Antoine
  full_name: Aubret, Antoine
  last_name: Aubret
- first_name: Quentin
  full_name: Martinet, Quentin
  id: b37485a8-d343-11eb-a0e9-df8c484ef8ab
  last_name: Martinet
  orcid: 0000-0002-2916-6632
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
citation:
  ama: Aubret A, Martinet Q, Palacci JA. Metamachines of pluripotent colloids. <i>Nature
    Communications</i>. 2021;12(1). doi:<a href="https://doi.org/10.1038/s41467-021-26699-6">10.1038/s41467-021-26699-6</a>
  apa: Aubret, A., Martinet, Q., &#38; Palacci, J. A. (2021). Metamachines of pluripotent
    colloids. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-021-26699-6">https://doi.org/10.1038/s41467-021-26699-6</a>
  chicago: Aubret, Antoine, Quentin Martinet, and Jérémie A Palacci. “Metamachines
    of Pluripotent Colloids.” <i>Nature Communications</i>. Springer Nature, 2021.
    <a href="https://doi.org/10.1038/s41467-021-26699-6">https://doi.org/10.1038/s41467-021-26699-6</a>.
  ieee: A. Aubret, Q. Martinet, and J. A. Palacci, “Metamachines of pluripotent colloids,”
    <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.
  ista: Aubret A, Martinet Q, Palacci JA. 2021. Metamachines of pluripotent colloids.
    Nature Communications. 12(1), 6398.
  mla: Aubret, Antoine, et al. “Metamachines of Pluripotent Colloids.” <i>Nature Communications</i>,
    vol. 12, no. 1, 6398, Springer Nature, 2021, doi:<a href="https://doi.org/10.1038/s41467-021-26699-6">10.1038/s41467-021-26699-6</a>.
  short: A. Aubret, Q. Martinet, J.A. Palacci, Nature Communications 12 (2021).
date_created: 2021-11-14T23:01:23Z
date_published: 2021-11-04T00:00:00Z
date_updated: 2023-08-14T11:48:37Z
day: '04'
ddc:
- '530'
department:
- _id: JePa
doi: 10.1038/s41467-021-26699-6
external_id:
  isi:
  - '000714754400010'
  pmid:
  - '34737315'
file:
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  date_updated: 2021-11-15T13:25:52Z
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intvolume: '        12'
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issue: '1'
language:
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month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Metamachines of pluripotent colloids
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
---
_id: '10322'
abstract:
- lang: eng
  text: To survive elevated temperatures, ectotherms adjust the fluidity of membranes
    by fine-tuning lipid desaturation levels in a process previously described to
    be cell autonomous. We have discovered that, in Caenorhabditis elegans, neuronal
    heat shock factor 1 (HSF-1), the conserved master regulator of the heat shock
    response (HSR), causes extensive fat remodeling in peripheral tissues. These changes
    include a decrease in fat desaturase and acid lipase expression in the intestine
    and a global shift in the saturation levels of plasma membrane’s phospholipids.
    The observed remodeling of plasma membrane is in line with ectothermic adaptive
    responses and gives worms a cumulative advantage to warm temperatures. We have
    determined that at least 6 TAX-2/TAX-4 cyclic guanosine monophosphate (cGMP) gated
    channel expressing sensory neurons, and transforming growth factor ß (TGF-β)/bone
    morphogenetic protein (BMP) are required for signaling across tissues to modulate
    fat desaturation. We also find neuronal hsf-1 is not only sufficient but also
    partially necessary to control the fat remodeling response and for survival at
    warm temperatures. This is the first study to show that a thermostat-based mechanism
    can cell nonautonomously coordinate membrane saturation and composition across
    tissues in a multicellular animal.
acknowledgement: We dedicate this work to the memory of Michael J.O. Wakelam. We would
  like to acknowledge Michael Fasseas (Invermis, Magnitude Biosciences) for plasmid
  injections and Sunny Biotech for transgenics; Catalina Vallejos and John Marioni
  for statistical advice at the beginning of the work; Simon Walker, Imaging, Bioinformatics
  and Lipidomics Facilities at Babraham Institute for technical support; and Cindy
  Voisine, Michael Witting, Jon Houseley, Len Stephens, Carmen Nussbaum Krammer, Rebeca
  Aldunate, Patricija van Oosten-Hawle, Jean-Louis Bessereau, and Jane Alfred for
  feedback on the manuscript. We thank Andy Dillin, Atsushi Kuhara, Amy Walker, Andrew
  Leifer, Yun Zhang, and Michalis Barkoulas for reagents and Julie Ahringer, Anne
  Ferguson-Smith, and Anne Corcoran for support and helpful discussions. We also acknowledge
  Babraham Institute Facilities.
article_number: e3001431
article_processing_charge: No
article_type: original
author:
- first_name: Laetitia
  full_name: Chauve, Laetitia
  last_name: Chauve
- first_name: Francesca
  full_name: Hodge, Francesca
  last_name: Hodge
- first_name: Sharlene
  full_name: Murdoch, Sharlene
  last_name: Murdoch
- first_name: Fatemah
  full_name: Masoudzadeh, Fatemah
  last_name: Masoudzadeh
- first_name: Harry Jack
  full_name: Mann, Harry Jack
  last_name: Mann
- first_name: Andrea
  full_name: Lopez-Clavijo, Andrea
  last_name: Lopez-Clavijo
- first_name: Hanneke
  full_name: Okkenhaug, Hanneke
  last_name: Okkenhaug
- first_name: Greg
  full_name: West, Greg
  last_name: West
- first_name: Bebiana C.
  full_name: Sousa, Bebiana C.
  last_name: Sousa
- first_name: Anne
  full_name: Segonds-Pichon, Anne
  last_name: Segonds-Pichon
- first_name: Cheryl
  full_name: Li, Cheryl
  last_name: Li
- first_name: Steven
  full_name: Wingett, Steven
  last_name: Wingett
- first_name: Hermine
  full_name: Kienberger, Hermine
  last_name: Kienberger
- first_name: Karin
  full_name: Kleigrewe, Karin
  last_name: Kleigrewe
- first_name: Mario
  full_name: De Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: De Bono
  orcid: 0000-0001-8347-0443
- first_name: Michael
  full_name: Wakelam, Michael
  last_name: Wakelam
- first_name: Olivia
  full_name: Casanueva, Olivia
  last_name: Casanueva
citation:
  ama: Chauve L, Hodge F, Murdoch S, et al. Neuronal HSF-1 coordinates the propagation
    of fat desaturation across tissues to enable adaptation to high temperatures in
    C. elegans. <i>PLoS Biology</i>. 2021;19(11). doi:<a href="https://doi.org/10.1371/journal.pbio.3001431">10.1371/journal.pbio.3001431</a>
  apa: Chauve, L., Hodge, F., Murdoch, S., Masoudzadeh, F., Mann, H. J., Lopez-Clavijo,
    A., … Casanueva, O. (2021). Neuronal HSF-1 coordinates the propagation of fat
    desaturation across tissues to enable adaptation to high temperatures in C. elegans.
    <i>PLoS Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pbio.3001431">https://doi.org/10.1371/journal.pbio.3001431</a>
  chicago: Chauve, Laetitia, Francesca Hodge, Sharlene Murdoch, Fatemah Masoudzadeh,
    Harry Jack Mann, Andrea Lopez-Clavijo, Hanneke Okkenhaug, et al. “Neuronal HSF-1
    Coordinates the Propagation of Fat Desaturation across Tissues to Enable Adaptation
    to High Temperatures in C. Elegans.” <i>PLoS Biology</i>. Public Library of Science,
    2021. <a href="https://doi.org/10.1371/journal.pbio.3001431">https://doi.org/10.1371/journal.pbio.3001431</a>.
  ieee: L. Chauve <i>et al.</i>, “Neuronal HSF-1 coordinates the propagation of fat
    desaturation across tissues to enable adaptation to high temperatures in C. elegans,”
    <i>PLoS Biology</i>, vol. 19, no. 11. Public Library of Science, 2021.
  ista: Chauve L, Hodge F, Murdoch S, Masoudzadeh F, Mann HJ, Lopez-Clavijo A, Okkenhaug
    H, West G, Sousa BC, Segonds-Pichon A, Li C, Wingett S, Kienberger H, Kleigrewe
    K, de Bono M, Wakelam M, Casanueva O. 2021. Neuronal HSF-1 coordinates the propagation
    of fat desaturation across tissues to enable adaptation to high temperatures in
    C. elegans. PLoS Biology. 19(11), e3001431.
  mla: Chauve, Laetitia, et al. “Neuronal HSF-1 Coordinates the Propagation of Fat
    Desaturation across Tissues to Enable Adaptation to High Temperatures in C. Elegans.”
    <i>PLoS Biology</i>, vol. 19, no. 11, e3001431, Public Library of Science, 2021,
    doi:<a href="https://doi.org/10.1371/journal.pbio.3001431">10.1371/journal.pbio.3001431</a>.
  short: L. Chauve, F. Hodge, S. Murdoch, F. Masoudzadeh, H.J. Mann, A. Lopez-Clavijo,
    H. Okkenhaug, G. West, B.C. Sousa, A. Segonds-Pichon, C. Li, S. Wingett, H. Kienberger,
    K. Kleigrewe, M. de Bono, M. Wakelam, O. Casanueva, PLoS Biology 19 (2021).
date_created: 2021-11-21T23:01:28Z
date_published: 2021-11-01T00:00:00Z
date_updated: 2023-08-14T11:53:27Z
day: '01'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1371/journal.pbio.3001431
external_id:
  isi:
  - '000715818400001'
  pmid:
  - '34723964'
file:
- access_level: open_access
  checksum: 0c61b667f814fd9435b3ac42036fc36d
  content_type: application/pdf
  creator: cchlebak
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  date_updated: 2021-11-22T09:34:03Z
  file_id: '10330'
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intvolume: '        19'
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- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Biology
publication_identifier:
  eissn:
  - 1545-7885
  issn:
  - 1544-9173
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
  record:
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    status: public
scopus_import: '1'
status: public
title: Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues
  to enable adaptation to high temperatures in C. elegans
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 19
year: '2021'
...
---
_id: '10367'
abstract:
- lang: eng
  text: How information is created, shared and consumed has changed rapidly in recent
    decades, in part thanks to new social platforms and technologies on the web. With
    ever-larger amounts of unstructured and limited labels, organizing and reconciling
    information from different sources and modalities is a central challenge in machine
    learning. This cutting-edge tutorial aims to introduce the multimodal entailment
    task, which can be useful for detecting semantic alignments when a single modality
    alone does not suffice for a whole content understanding. Starting with a brief
    overview of natural language processing, computer vision, structured data and
    neural graph learning, we lay the foundations for the multimodal sections to follow.
    We then discuss recent multimodal learning literature covering visual, audio and
    language streams, and explore case studies focusing on tasks which require fine-grained
    understanding of visual and linguistic semantics question answering, veracity
    and hatred classification. Finally, we introduce a new dataset for recognizing
    multimodal entailment, exploring it in a hands-on collaborative section. Overall,
    this tutorial gives an overview of multimodal learning, introduces a multimodal
    entailment dataset, and encourages future research in the topic.
acknowledgement: "We would like to thank Abby Schantz, Abe Ittycheriah, Aliaksei Severyn,
  Allan Heydon, Aly\r\nGrealish, Andrey Vlasov, Arkaitz Zubiaga, Ashwin Kakarla, Chen
  Sun, Clayton Williams, Cong\r\nYu, Cordelia Schmid, Da-Cheng Juan, Dan Finnie, Dani
  Valevski, Daniel Rocha, David Price, David Sklar, Devi Krishna, Elena Kochkina,
  Enrique Alfonseca, Franc¸oise Beaufays, Isabelle Augenstein, Jialu Liu, John Cantwell,
  John Palowitch, Jordan Boyd-Graber, Lei Shi, Luis Valente, Maria Voitovich, Mehmet
  Aktuna, Mogan Brown, Mor Naaman, Natalia P, Nidhi Hebbar, Pete Aykroyd, Rahul Sukthankar,
  Richa Dixit, Steve Pucci, Tania Bedrax-Weiss, Tobias Kaufmann, Tom Boulos, Tu Tsao,
  Vladimir Chtchetkine, Yair Kurzion, Yifan Xu and Zach Hynes."
article_processing_charge: No
author:
- first_name: Cesar
  full_name: Ilharco, Cesar
  last_name: Ilharco
- first_name: Afsaneh
  full_name: Shirazi, Afsaneh
  last_name: Shirazi
- first_name: Arjun
  full_name: Gopalan, Arjun
  last_name: Gopalan
- first_name: Arsha
  full_name: Nagrani, Arsha
  last_name: Nagrani
- first_name: Blaž
  full_name: Bratanič, Blaž
  last_name: Bratanič
- first_name: Chris
  full_name: Bregler, Chris
  last_name: Bregler
- first_name: Christina
  full_name: Liu, Christina
  last_name: Liu
- first_name: Felipe
  full_name: Ferreira, Felipe
  last_name: Ferreira
- first_name: Gabriek
  full_name: Barcik, Gabriek
  last_name: Barcik
- first_name: Gabriel
  full_name: Ilharco, Gabriel
  last_name: Ilharco
- first_name: Georg F
  full_name: Osang, Georg F
  id: 464B40D6-F248-11E8-B48F-1D18A9856A87
  last_name: Osang
- first_name: Jannis
  full_name: Bulian, Jannis
  last_name: Bulian
- first_name: Jared
  full_name: Frank, Jared
  last_name: Frank
- first_name: Lucas
  full_name: Smaira, Lucas
  last_name: Smaira
- first_name: Qin
  full_name: Cao, Qin
  last_name: Cao
- first_name: Ricardo
  full_name: Marino, Ricardo
  last_name: Marino
- first_name: Roma
  full_name: Patel, Roma
  last_name: Patel
- first_name: Thomas
  full_name: Leung, Thomas
  last_name: Leung
- first_name: Vaiva
  full_name: Imbrasaite, Vaiva
  last_name: Imbrasaite
citation:
  ama: 'Ilharco C, Shirazi A, Gopalan A, et al. Recognizing multimodal entailment.
    In: <i>59th Annual Meeting of the Association for Computational Linguistics and
    the 11th International Joint Conference on Natural Language Processing, Tutorial
    Abstracts</i>. Association for Computational Linguistics; 2021:29-30. doi:<a href="https://doi.org/10.18653/v1/2021.acl-tutorials.6">10.18653/v1/2021.acl-tutorials.6</a>'
  apa: 'Ilharco, C., Shirazi, A., Gopalan, A., Nagrani, A., Bratanič, B., Bregler,
    C., … Imbrasaite, V. (2021). Recognizing multimodal entailment. In <i>59th Annual
    Meeting of the Association for Computational Linguistics and the 11th International
    Joint Conference on Natural Language Processing, Tutorial Abstracts</i> (pp. 29–30).
    Bangkok, Thailand: Association for Computational Linguistics. <a href="https://doi.org/10.18653/v1/2021.acl-tutorials.6">https://doi.org/10.18653/v1/2021.acl-tutorials.6</a>'
  chicago: Ilharco, Cesar, Afsaneh Shirazi, Arjun Gopalan, Arsha Nagrani, Blaž Bratanič,
    Chris Bregler, Christina Liu, et al. “Recognizing Multimodal Entailment.” In <i>59th
    Annual Meeting of the Association for Computational Linguistics and the 11th International
    Joint Conference on Natural Language Processing, Tutorial Abstracts</i>, 29–30.
    Association for Computational Linguistics, 2021. <a href="https://doi.org/10.18653/v1/2021.acl-tutorials.6">https://doi.org/10.18653/v1/2021.acl-tutorials.6</a>.
  ieee: C. Ilharco <i>et al.</i>, “Recognizing multimodal entailment,” in <i>59th
    Annual Meeting of the Association for Computational Linguistics and the 11th International
    Joint Conference on Natural Language Processing, Tutorial Abstracts</i>, Bangkok,
    Thailand, 2021, pp. 29–30.
  ista: 'Ilharco C, Shirazi A, Gopalan A, Nagrani A, Bratanič B, Bregler C, Liu C,
    Ferreira F, Barcik G, Ilharco G, Osang GF, Bulian J, Frank J, Smaira L, Cao Q,
    Marino R, Patel R, Leung T, Imbrasaite V. 2021. Recognizing multimodal entailment.
    59th Annual Meeting of the Association for Computational Linguistics and the 11th
    International Joint Conference on Natural Language Processing, Tutorial Abstracts.
    ACL: Association for Computational Linguistics ; IJCNLP: International Joint Conference
    on Natural Language Processing, 29–30.'
  mla: Ilharco, Cesar, et al. “Recognizing Multimodal Entailment.” <i>59th Annual
    Meeting of the Association for Computational Linguistics and the 11th International
    Joint Conference on Natural Language Processing, Tutorial Abstracts</i>, Association
    for Computational Linguistics, 2021, pp. 29–30, doi:<a href="https://doi.org/10.18653/v1/2021.acl-tutorials.6">10.18653/v1/2021.acl-tutorials.6</a>.
  short: C. Ilharco, A. Shirazi, A. Gopalan, A. Nagrani, B. Bratanič, C. Bregler,
    C. Liu, F. Ferreira, G. Barcik, G. Ilharco, G.F. Osang, J. Bulian, J. Frank, L.
    Smaira, Q. Cao, R. Marino, R. Patel, T. Leung, V. Imbrasaite, in:, 59th Annual
    Meeting of the Association for Computational Linguistics and the 11th International
    Joint Conference on Natural Language Processing, Tutorial Abstracts, Association
    for Computational Linguistics, 2021, pp. 29–30.
conference:
  end_date: 2021-08-06
  location: Bangkok, Thailand
  name: 'ACL: Association for Computational Linguistics ; IJCNLP: International Joint
    Conference on Natural Language Processing'
  start_date: 2021-08-01
date_created: 2021-11-28T23:01:30Z
date_published: 2021-08-01T00:00:00Z
date_updated: 2022-01-26T14:26:36Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.18653/v1/2021.acl-tutorials.6
file:
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  checksum: b14052a025a6ecf675bdfe51db98c0d7
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-11-29T08:41:00Z
  date_updated: 2021-11-29T08:41:00Z
  file_id: '10368'
  file_name: 2021_ACL_Ilharco.pdf
  file_size: 1227703
  relation: main_file
  success: 1
file_date_updated: 2021-11-29T08:41:00Z
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://aclanthology.org/2021.acl-tutorials.6/
month: '08'
oa: 1
oa_version: Published Version
page: 29-30
publication: 59th Annual Meeting of the Association for Computational Linguistics
  and the 11th International Joint Conference on Natural Language Processing, Tutorial
  Abstracts
publication_identifier:
  isbn:
  - 9-781-9540-8557-2
publication_status: published
publisher: Association for Computational Linguistics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Recognizing multimodal entailment
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2021'
...
---
_id: '17577'
abstract:
- lang: eng
  text: 'The Legacy Survey of Space and Time (LSST) by the Vera C. Rubin Observatory
    is expected to discover tens of millions of quasars. A significant fraction of
    these could be powered by coalescing massive black hole (MBH) binaries, since
    many quasars are believed to be triggered by mergers. We show that under plausible
    assumptions about the luminosity functions, lifetimes, and binary fractions of
    quasars, we expect the full LSST quasar catalogue to contain between 20 and 100
    million compact MBH binaries with masses M = 105–9M⊙, redshifts z = 0–6, and orbital
    periods P = 1–70 d. Their light-curves are expected to be distinctly periodic,
    which can be confidently distinguished from stochastic red-noise variability,
    because LSST will cover dozens, or even hundreds of cycles. A very small subset
    of 10–150 ultracompact (P ≲ 1 d) binary quasars among these will, over ∼5–15 yr,
    evolve into the mHz gravitational-wave frequency band and can be detected by LISA.
    They can therefore be regarded as ‘LISA verification binaries’, analogous to short-period
    Galactic compact-object binaries. The practical question is how to find these
    handful of ‘needles in the haystack’ among the large number of quasars: this will
    likely require a tailored co-adding analysis optimized for this purpose.'
article_processing_charge: No
article_type: original
author:
- first_name: Chengcheng
  full_name: Xin, Chengcheng
  last_name: Xin
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Xin C, Haiman Z. Ultra-short-period massive black hole binary candidates in
    LSST as LISA ‘verification binaries.’ <i>Monthly Notices of the Royal Astronomical
    Society</i>. 2021;506(2):2408-2417. doi:<a href="https://doi.org/10.1093/mnras/stab1856">10.1093/mnras/stab1856</a>
  apa: Xin, C., &#38; Haiman, Z. (2021). Ultra-short-period massive black hole binary
    candidates in LSST as LISA ‘verification binaries.’ <i>Monthly Notices of the
    Royal Astronomical Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/stab1856">https://doi.org/10.1093/mnras/stab1856</a>
  chicago: Xin, Chengcheng, and Zoltán Haiman. “Ultra-Short-Period Massive Black Hole
    Binary Candidates in LSST as LISA ‘Verification Binaries.’” <i>Monthly Notices
    of the Royal Astronomical Society</i>. Oxford University Press, 2021. <a href="https://doi.org/10.1093/mnras/stab1856">https://doi.org/10.1093/mnras/stab1856</a>.
  ieee: C. Xin and Z. Haiman, “Ultra-short-period massive black hole binary candidates
    in LSST as LISA ‘verification binaries,’” <i>Monthly Notices of the Royal Astronomical
    Society</i>, vol. 506, no. 2. Oxford University Press, pp. 2408–2417, 2021.
  ista: Xin C, Haiman Z. 2021. Ultra-short-period massive black hole binary candidates
    in LSST as LISA ‘verification binaries’. Monthly Notices of the Royal Astronomical
    Society. 506(2), 2408–2417.
  mla: Xin, Chengcheng, and Zoltán Haiman. “Ultra-Short-Period Massive Black Hole
    Binary Candidates in LSST as LISA ‘Verification Binaries.’” <i>Monthly Notices
    of the Royal Astronomical Society</i>, vol. 506, no. 2, Oxford University Press,
    2021, pp. 2408–17, doi:<a href="https://doi.org/10.1093/mnras/stab1856">10.1093/mnras/stab1856</a>.
  short: C. Xin, Z. Haiman, Monthly Notices of the Royal Astronomical Society 506
    (2021) 2408–2417.
date_created: 2024-09-05T12:19:58Z
date_published: 2021-07-05T00:00:00Z
date_updated: 2024-09-19T08:07:41Z
day: '05'
doi: 10.1093/mnras/stab1856
extern: '1'
intvolume: '       506'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/mnras/stab1856
month: '07'
oa: 1
oa_version: Published Version
page: 2408-2417
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  issn:
  - 0035-8711
  - 1365-2966
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ultra-short-period massive black hole binary candidates in LSST as LISA ‘verification
  binaries’
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 506
year: '2021'
...
---
_id: '17578'
abstract:
- lang: eng
  text: "If primordial black holes (PBHs) seeded the supermassive black holes (SMBHs)
    at the centers of high-redshift quasars, then the gas surrounding these black
    holes may reveal nucleosynthetic clues to their primordial origins. We present
    predictions of altered primordial abundances around PBHs massive enough to seed
    SMBHs at \U0001D467≈6–7.5. We find that if PBHs with initial masses of ∼105  M⊙
    are responsible for such SMBHs, they may produce primordial deuterium and Helium
    fractions enhanced by ≥10%, and lithium abundance depleted by ≥10%, at distances
    of up to ≈ a comoving kiloparsec away from the black hole after decoupling. We
    estimate that ∼108  M⊙ of gas is enhanced (or depleted) by at least one percent.
    Evidence of these modified primordial deuterium, helium, and lithium abundances
    could still be present if this circum-PBH gas remains unaccreted by the SMBH and
    in or near the host galaxies of high-redshift quasars. Measuring the abundance
    anomalies will be challenging, but could offer a novel way to reveal the primordial
    origin of such SMBH seeds."
article_number: '103022'
article_processing_charge: No
article_type: original
author:
- first_name: Phoebe Upton
  full_name: Sanderbeck, Phoebe Upton
  last_name: Sanderbeck
- first_name: Simeon
  full_name: Bird, Simeon
  last_name: Bird
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: Sanderbeck PU, Bird S, Haiman Z. Nucleosynthetic signatures of primordial origin
    around supermassive black holes. <i>Physical Review D</i>. 2021;104(10). doi:<a
    href="https://doi.org/10.1103/physrevd.104.103022">10.1103/physrevd.104.103022</a>
  apa: Sanderbeck, P. U., Bird, S., &#38; Haiman, Z. (2021). Nucleosynthetic signatures
    of primordial origin around supermassive black holes. <i>Physical Review D</i>.
    American Physical Society. <a href="https://doi.org/10.1103/physrevd.104.103022">https://doi.org/10.1103/physrevd.104.103022</a>
  chicago: Sanderbeck, Phoebe Upton, Simeon Bird, and Zoltán Haiman. “Nucleosynthetic
    Signatures of Primordial Origin around Supermassive Black Holes.” <i>Physical
    Review D</i>. American Physical Society, 2021. <a href="https://doi.org/10.1103/physrevd.104.103022">https://doi.org/10.1103/physrevd.104.103022</a>.
  ieee: P. U. Sanderbeck, S. Bird, and Z. Haiman, “Nucleosynthetic signatures of primordial
    origin around supermassive black holes,” <i>Physical Review D</i>, vol. 104, no.
    10. American Physical Society, 2021.
  ista: Sanderbeck PU, Bird S, Haiman Z. 2021. Nucleosynthetic signatures of primordial
    origin around supermassive black holes. Physical Review D. 104(10), 103022.
  mla: Sanderbeck, Phoebe Upton, et al. “Nucleosynthetic Signatures of Primordial
    Origin around Supermassive Black Holes.” <i>Physical Review D</i>, vol. 104, no.
    10, 103022, American Physical Society, 2021, doi:<a href="https://doi.org/10.1103/physrevd.104.103022">10.1103/physrevd.104.103022</a>.
  short: P.U. Sanderbeck, S. Bird, Z. Haiman, Physical Review D 104 (2021).
date_created: 2024-09-05T12:20:50Z
date_published: 2021-11-17T00:00:00Z
date_updated: 2024-09-19T08:12:35Z
day: '17'
doi: 10.1103/physrevd.104.103022
extern: '1'
intvolume: '       104'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1103/physrevd.104.103022
month: '11'
oa: 1
oa_version: Published Version
publication: Physical Review D
publication_identifier:
  issn:
  - 2470-0010
  - 2470-0029
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nucleosynthetic signatures of primordial origin around supermassive black holes
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 104
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '17592'
abstract:
- lang: eng
  text: Using high-resolution hydrodynamics simulations, we show that equal-mass binaries
    accreting from a circumbinary disk evolve toward an orbital eccentricity of e
    ≃ 0.45, unless they are initialized on a nearly circular orbit with e ≲ 0.08,
    in which case they further circularize. The implied bi-modal eccentricity distribution
    resembles that seen in post-AGB stellar binaries. Large accretion spikes around
    periapse impart a tell-tale, quasiperiodic, bursty signature on the light curves
    of eccentric binaries. We predict that intermediate-mass and massive black hole
    binaries at z ≲ 10 entering the LISA band will have measurable eccentricities
    in the range of e ≃ 10−3 − 10−2, if they have experienced a gas-driven phase.
    On the other hand, GW190521 would have entered the LIGO/Virgo band with undetectable
    eccentricity ∼10−6 if it had been driven into the gravitational-wave regime by
    a gas disk.
article_number: L13
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jonathan
  full_name: Zrake, Jonathan
  last_name: Zrake
- first_name: Christopher
  full_name: Tiede, Christopher
  last_name: Tiede
- first_name: Andrew
  full_name: MacFadyen, Andrew
  last_name: MacFadyen
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
  orcid: 0000-0003-3633-5403
citation:
  ama: Zrake J, Tiede C, MacFadyen A, Haiman Z. Equilibrium eccentricity of accreting
    binaries. <i>The Astrophysical Journal Letters</i>. 2021;909(1). doi:<a href="https://doi.org/10.3847/2041-8213/abdd1c">10.3847/2041-8213/abdd1c</a>
  apa: Zrake, J., Tiede, C., MacFadyen, A., &#38; Haiman, Z. (2021). Equilibrium eccentricity
    of accreting binaries. <i>The Astrophysical Journal Letters</i>. American Astronomical
    Society. <a href="https://doi.org/10.3847/2041-8213/abdd1c">https://doi.org/10.3847/2041-8213/abdd1c</a>
  chicago: Zrake, Jonathan, Christopher Tiede, Andrew MacFadyen, and Zoltán Haiman.
    “Equilibrium Eccentricity of Accreting Binaries.” <i>The Astrophysical Journal
    Letters</i>. American Astronomical Society, 2021. <a href="https://doi.org/10.3847/2041-8213/abdd1c">https://doi.org/10.3847/2041-8213/abdd1c</a>.
  ieee: J. Zrake, C. Tiede, A. MacFadyen, and Z. Haiman, “Equilibrium eccentricity
    of accreting binaries,” <i>The Astrophysical Journal Letters</i>, vol. 909, no.
    1. American Astronomical Society, 2021.
  ista: Zrake J, Tiede C, MacFadyen A, Haiman Z. 2021. Equilibrium eccentricity of
    accreting binaries. The Astrophysical Journal Letters. 909(1), L13.
  mla: Zrake, Jonathan, et al. “Equilibrium Eccentricity of Accreting Binaries.” <i>The
    Astrophysical Journal Letters</i>, vol. 909, no. 1, L13, American Astronomical
    Society, 2021, doi:<a href="https://doi.org/10.3847/2041-8213/abdd1c">10.3847/2041-8213/abdd1c</a>.
  short: J. Zrake, C. Tiede, A. MacFadyen, Z. Haiman, The Astrophysical Journal Letters
    909 (2021).
date_created: 2024-09-05T12:39:13Z
date_published: 2021-03-03T00:00:00Z
date_updated: 2025-01-03T11:32:01Z
day: '03'
doi: 10.3847/2041-8213/abdd1c
extern: '1'
external_id:
  arxiv:
  - '2010.09707'
intvolume: '       909'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2010.09707
month: '03'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal Letters
publication_identifier:
  eissn:
  - 2041-8213
  issn:
  - 2041-8205
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Equilibrium eccentricity of accreting binaries
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 909
year: '2021'
...
---
_id: '17593'
abstract:
- lang: eng
  text: The science objectives of the LISA mission have been defined under the implicit
    assumption of a 4-years continuous data stream. Based on the performance of LISA
    Pathfinder, it is now expected that LISA will have a duty cycle of ≈0.75 , which
    would reduce the effective span of usable data to 3 years. This paper reports
    the results of a study by the LISA Science Group, which was charged with assessing
    the additional science return of increasing the mission lifetime. We explore various
    observational scenarios to assess the impact of mission duration on the main science
    objectives of the mission. We find that the science investigations most affected
    by mission duration concern the search for seed black holes at cosmic dawn, as
    well as the study of stellar-origin black holes and of their formation channels
    via multi-band and multi-messenger observations. We conclude that an extension
    to 6 years of mission operations is recommended.
article_number: '3'
article_processing_charge: No
article_type: original
author:
- first_name: Pau
  full_name: Amaro Seoane, Pau
  last_name: Amaro Seoane
- first_name: Manuel
  full_name: Arca Sedda, Manuel
  last_name: Arca Sedda
- first_name: Stanislav
  full_name: Babak, Stanislav
  last_name: Babak
- first_name: Christopher P. L.
  full_name: Berry, Christopher P. L.
  last_name: Berry
- first_name: Emanuele
  full_name: Berti, Emanuele
  last_name: Berti
- first_name: Gianfranco
  full_name: Bertone, Gianfranco
  last_name: Bertone
- first_name: Diego
  full_name: Blas, Diego
  last_name: Blas
- first_name: Tamara
  full_name: Bogdanović, Tamara
  last_name: Bogdanović
- first_name: Matteo
  full_name: Bonetti, Matteo
  last_name: Bonetti
- first_name: Katelyn
  full_name: Breivik, Katelyn
  last_name: Breivik
- first_name: Richard
  full_name: Brito, Richard
  last_name: Brito
- first_name: Robert
  full_name: Caldwell, Robert
  last_name: Caldwell
- first_name: Pedro R.
  full_name: Capelo, Pedro R.
  last_name: Capelo
- first_name: Chiara
  full_name: Caprini, Chiara
  last_name: Caprini
- first_name: Vitor
  full_name: Cardoso, Vitor
  last_name: Cardoso
- first_name: Zack
  full_name: Carson, Zack
  last_name: Carson
- first_name: Hsin-Yu
  full_name: Chen, Hsin-Yu
  last_name: Chen
- first_name: Alvin J. K.
  full_name: Chua, Alvin J. K.
  last_name: Chua
- first_name: Irina
  full_name: Dvorkin, Irina
  last_name: Dvorkin
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Lavinia
  full_name: Heisenberg, Lavinia
  last_name: Heisenberg
- first_name: Maximiliano
  full_name: Isi, Maximiliano
  last_name: Isi
- first_name: Nikolaos
  full_name: Karnesis, Nikolaos
  last_name: Karnesis
- first_name: Bradley J.
  full_name: Kavanagh, Bradley J.
  last_name: Kavanagh
- first_name: Tyson B.
  full_name: Littenberg, Tyson B.
  last_name: Littenberg
- first_name: Alberto
  full_name: Mangiagli, Alberto
  last_name: Mangiagli
- first_name: Paolo
  full_name: Marcoccia, Paolo
  last_name: Marcoccia
- first_name: Andrea
  full_name: Maselli, Andrea
  last_name: Maselli
- first_name: Germano
  full_name: Nardini, Germano
  last_name: Nardini
- first_name: Paolo
  full_name: Pani, Paolo
  last_name: Pani
- first_name: Marco
  full_name: Peloso, Marco
  last_name: Peloso
- first_name: Mauro
  full_name: Pieroni, Mauro
  last_name: Pieroni
- first_name: Angelo
  full_name: Ricciardone, Angelo
  last_name: Ricciardone
- first_name: Alberto
  full_name: Sesana, Alberto
  last_name: Sesana
- first_name: Nicola
  full_name: Tamanini, Nicola
  last_name: Tamanini
- first_name: Alexandre
  full_name: Toubiana, Alexandre
  last_name: Toubiana
- first_name: Rosa
  full_name: Valiante, Rosa
  last_name: Valiante
- first_name: Stamatis
  full_name: Vretinaris, Stamatis
  last_name: Vretinaris
- first_name: David J.
  full_name: Weir, David J.
  last_name: Weir
- first_name: Kent
  full_name: Yagi, Kent
  last_name: Yagi
- first_name: Aaron
  full_name: Zimmerman, Aaron
  last_name: Zimmerman
citation:
  ama: Amaro Seoane P, Arca Sedda M, Babak S, et al. The effect of mission duration
    on LISA science objectives. <i>General Relativity and Gravitation</i>. 2021;54(1).
    doi:<a href="https://doi.org/10.1007/s10714-021-02889-x">10.1007/s10714-021-02889-x</a>
  apa: Amaro Seoane, P., Arca Sedda, M., Babak, S., Berry, C. P. L., Berti, E., Bertone,
    G., … Zimmerman, A. (2021). The effect of mission duration on LISA science objectives.
    <i>General Relativity and Gravitation</i>. Springer Science and Business Media
    LLC. <a href="https://doi.org/10.1007/s10714-021-02889-x">https://doi.org/10.1007/s10714-021-02889-x</a>
  chicago: Amaro Seoane, Pau, Manuel Arca Sedda, Stanislav Babak, Christopher P. L.
    Berry, Emanuele Berti, Gianfranco Bertone, Diego Blas, et al. “The Effect of Mission
    Duration on LISA Science Objectives.” <i>General Relativity and Gravitation</i>.
    Springer Science and Business Media LLC, 2021. <a href="https://doi.org/10.1007/s10714-021-02889-x">https://doi.org/10.1007/s10714-021-02889-x</a>.
  ieee: P. Amaro Seoane <i>et al.</i>, “The effect of mission duration on LISA science
    objectives,” <i>General Relativity and Gravitation</i>, vol. 54, no. 1. Springer
    Science and Business Media LLC, 2021.
  ista: Amaro Seoane P, Arca Sedda M, Babak S, Berry CPL, Berti E, Bertone G, Blas
    D, Bogdanović T, Bonetti M, Breivik K, Brito R, Caldwell R, Capelo PR, Caprini
    C, Cardoso V, Carson Z, Chen H-Y, Chua AJK, Dvorkin I, Haiman Z, Heisenberg L,
    Isi M, Karnesis N, Kavanagh BJ, Littenberg TB, Mangiagli A, Marcoccia P, Maselli
    A, Nardini G, Pani P, Peloso M, Pieroni M, Ricciardone A, Sesana A, Tamanini N,
    Toubiana A, Valiante R, Vretinaris S, Weir DJ, Yagi K, Zimmerman A. 2021. The
    effect of mission duration on LISA science objectives. General Relativity and
    Gravitation. 54(1), 3.
  mla: Amaro Seoane, Pau, et al. “The Effect of Mission Duration on LISA Science Objectives.”
    <i>General Relativity and Gravitation</i>, vol. 54, no. 1, 3, Springer Science
    and Business Media LLC, 2021, doi:<a href="https://doi.org/10.1007/s10714-021-02889-x">10.1007/s10714-021-02889-x</a>.
  short: P. Amaro Seoane, M. Arca Sedda, S. Babak, C.P.L. Berry, E. Berti, G. Bertone,
    D. Blas, T. Bogdanović, M. Bonetti, K. Breivik, R. Brito, R. Caldwell, P.R. Capelo,
    C. Caprini, V. Cardoso, Z. Carson, H.-Y. Chen, A.J.K. Chua, I. Dvorkin, Z. Haiman,
    L. Heisenberg, M. Isi, N. Karnesis, B.J. Kavanagh, T.B. Littenberg, A. Mangiagli,
    P. Marcoccia, A. Maselli, G. Nardini, P. Pani, M. Peloso, M. Pieroni, A. Ricciardone,
    A. Sesana, N. Tamanini, A. Toubiana, R. Valiante, S. Vretinaris, D.J. Weir, K.
    Yagi, A. Zimmerman, General Relativity and Gravitation 54 (2021).
date_created: 2024-09-05T12:40:14Z
date_published: 2021-12-27T00:00:00Z
date_updated: 2024-09-23T12:32:50Z
day: '27'
doi: 10.1007/s10714-021-02889-x
extern: '1'
intvolume: '        54'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s10714-021-02889-x
month: '12'
oa: 1
oa_version: Published Version
publication: General Relativity and Gravitation
publication_identifier:
  issn:
  - 0001-7701
  - 1572-9532
publication_status: published
publisher: Springer Science and Business Media LLC
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effect of mission duration on LISA science objectives
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 54
year: '2021'
...
---
_id: '17610'
abstract:
- lang: eng
  text: 'The presence of massive black holes (BHs) with masses of order 109M⊙, powering
    bright quasars when the Universe was less than 1 Gyr old, poses strong constraints
    on their formation mechanism. Several scenarios have been proposed to date to
    explain massive BH formation, from the low-mass seed BH remnants of the first
    generation of stars to the massive seed BHs resulting from the rapid collapse
    of massive gas clouds. However, the plausibility of some of these scenarios to
    occur within the progenitors of high-z quasars has not yet been thoroughly explored.
    In this work, we investigate, by combining dark-matter only N-body simulations
    with a semi-analytic framework, whether the conditions for the formation of massive
    seed BHs from synchronised atomic-cooling halo pairs and/or dynamically-heated
    mini-haloes are fulfilled in the overdense regions where the progenitors of a
    typical high-redshift quasar host form and evolve. Our analysis shows that the
    peculiar conditions in such regions, i.e. strong halo clustering and high star
    formation rates, are crucial to produce a non-negligible number of massive seed
    BH host candidates: we find ≈1400 dynamically heated metal-free mini-haloes, including
    one of these which evolves to a synchronised pair and ends up in the massive quasar-host
    halo by z=6. This demonstrates that the progenitors of high-redshift quasar host
    haloes can harbour early massive seed BHs. Our results further suggest that multiple
    massive seed BHs may form in or near the quasar host''s progenitors, potentially
    merging at lower redshifts and yielding gravitational wave events.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alessandro
  full_name: Lupi, Alessandro
  last_name: Lupi
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Marta
  full_name: Volonteri, Marta
  last_name: Volonteri
citation:
  ama: Lupi A, Haiman Z, Volonteri M. Forming massive seed black holes in high-redshift
    quasar host progenitors. <i>Monthly Notices of the Royal Astronomical Society</i>.
    2021;503(4):5046-5060. doi:<a href="https://doi.org/10.1093/mnras/stab692">10.1093/mnras/stab692</a>
  apa: Lupi, A., Haiman, Z., &#38; Volonteri, M. (2021). Forming massive seed black
    holes in high-redshift quasar host progenitors. <i>Monthly Notices of the Royal
    Astronomical Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/stab692">https://doi.org/10.1093/mnras/stab692</a>
  chicago: Lupi, Alessandro, Zoltán Haiman, and Marta Volonteri. “Forming Massive
    Seed Black Holes in High-Redshift Quasar Host Progenitors.” <i>Monthly Notices
    of the Royal Astronomical Society</i>. Oxford University Press, 2021. <a href="https://doi.org/10.1093/mnras/stab692">https://doi.org/10.1093/mnras/stab692</a>.
  ieee: A. Lupi, Z. Haiman, and M. Volonteri, “Forming massive seed black holes in
    high-redshift quasar host progenitors,” <i>Monthly Notices of the Royal Astronomical
    Society</i>, vol. 503, no. 4. Oxford University Press, pp. 5046–5060, 2021.
  ista: Lupi A, Haiman Z, Volonteri M. 2021. Forming massive seed black holes in high-redshift
    quasar host progenitors. Monthly Notices of the Royal Astronomical Society. 503(4),
    5046–5060.
  mla: Lupi, Alessandro, et al. “Forming Massive Seed Black Holes in High-Redshift
    Quasar Host Progenitors.” <i>Monthly Notices of the Royal Astronomical Society</i>,
    vol. 503, no. 4, Oxford University Press, 2021, pp. 5046–60, doi:<a href="https://doi.org/10.1093/mnras/stab692">10.1093/mnras/stab692</a>.
  short: A. Lupi, Z. Haiman, M. Volonteri, Monthly Notices of the Royal Astronomical
    Society 503 (2021) 5046–5060.
date_created: 2024-09-05T13:22:23Z
date_published: 2021-03-24T00:00:00Z
date_updated: 2024-09-23T14:49:49Z
day: '24'
doi: 10.1093/mnras/stab692
extern: '1'
external_id:
  arxiv:
  - '2102.05051'
intvolume: '       503'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2102.05051'
month: '03'
oa: 1
oa_version: Preprint
page: 5046-5060
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  issn:
  - 0035-8711
  - 1365-2966
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Forming massive seed black holes in high-redshift quasar host progenitors
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 503
year: '2021'
...
---
_id: '7941'
abstract:
- lang: eng
  text: Expansion microscopy is a recently developed super-resolution imaging technique,
    which provides an alternative to optics-based methods such as deterministic approaches
    (e.g. STED) or stochastic approaches (e.g. PALM/STORM). The idea behind expansion
    microscopy is to embed the biological sample in a swellable gel, and then to expand
    it isotropically, thereby increasing the distance between the fluorophores. This
    approach breaks the diffraction barrier by simply separating the emission point-spread-functions
    of the fluorophores. The resolution attainable in expansion microscopy is thus
    directly dependent on the separation that can be achieved, i.e. on the expansion
    factor. The original implementation of the technique achieved an expansion factor
    of fourfold, for a resolution of 70–80 nm. The subsequently developed X10 method
    achieves an expansion factor of 10-fold, for a resolution of 25–30 nm. This technique
    can be implemented with minimal technical requirements on any standard fluorescence
    microscope, and is more easily applied for multi-color imaging than either deterministic
    or stochastic super-resolution approaches. This renders X10 expansion microscopy
    a highly promising tool for new biological discoveries, as discussed here, and
    as demonstrated by several recent applications.
article_processing_charge: No
author:
- first_name: Sven M
  full_name: Truckenbrodt, Sven M
  id: 45812BD4-F248-11E8-B48F-1D18A9856A87
  last_name: Truckenbrodt
- first_name: Silvio O.
  full_name: Rizzoli, Silvio O.
  last_name: Rizzoli
citation:
  ama: 'Truckenbrodt SM, Rizzoli SO. Simple multi-color super-resolution by X10 microscopy.
    In: <i>Methods in Cell Biology</i>. Vol 161. Elsevier; 2021:33-56. doi:<a href="https://doi.org/10.1016/bs.mcb.2020.04.016">10.1016/bs.mcb.2020.04.016</a>'
  apa: Truckenbrodt, S. M., &#38; Rizzoli, S. O. (2021). Simple multi-color super-resolution
    by X10 microscopy. In <i>Methods in Cell Biology</i> (Vol. 161, pp. 33–56). Elsevier.
    <a href="https://doi.org/10.1016/bs.mcb.2020.04.016">https://doi.org/10.1016/bs.mcb.2020.04.016</a>
  chicago: Truckenbrodt, Sven M, and Silvio O. Rizzoli. “Simple Multi-Color Super-Resolution
    by X10 Microscopy.” In <i>Methods in Cell Biology</i>, 161:33–56. Elsevier, 2021.
    <a href="https://doi.org/10.1016/bs.mcb.2020.04.016">https://doi.org/10.1016/bs.mcb.2020.04.016</a>.
  ieee: S. M. Truckenbrodt and S. O. Rizzoli, “Simple multi-color super-resolution
    by X10 microscopy,” in <i>Methods in Cell Biology</i>, vol. 161, Elsevier, 2021,
    pp. 33–56.
  ista: 'Truckenbrodt SM, Rizzoli SO. 2021.Simple multi-color super-resolution by
    X10 microscopy. In: Methods in Cell Biology. vol. 161, 33–56.'
  mla: Truckenbrodt, Sven M., and Silvio O. Rizzoli. “Simple Multi-Color Super-Resolution
    by X10 Microscopy.” <i>Methods in Cell Biology</i>, vol. 161, Elsevier, 2021,
    pp. 33–56, doi:<a href="https://doi.org/10.1016/bs.mcb.2020.04.016">10.1016/bs.mcb.2020.04.016</a>.
  short: S.M. Truckenbrodt, S.O. Rizzoli, in:, Methods in Cell Biology, Elsevier,
    2021, pp. 33–56.
corr_author: '1'
date_created: 2020-06-07T22:00:55Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2024-10-09T20:59:36Z
day: '01'
department:
- _id: JoDa
doi: 10.1016/bs.mcb.2020.04.016
external_id:
  pmid:
  - '33478696'
intvolume: '       161'
language:
- iso: eng
month: '01'
oa_version: None
page: 33-56
pmid: 1
publication: Methods in Cell Biology
publication_identifier:
  isbn:
  - 978012820807-6
  issn:
  - 0091-679X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simple multi-color super-resolution by X10 microscopy
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 161
year: '2021'
...
---
_id: '8757'
abstract:
- lang: eng
  text: Traditional scientific conferences and seminar events have been hugely disrupted
    by the COVID-19 pandemic, paving the way for virtual forms of scientific communication
    to take hold and be put to the test.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Panagiotis
  full_name: Bozelos, Panagiotis
  id: 52e9c652-2982-11eb-81d4-b43d94c63700
  last_name: Bozelos
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
citation:
  ama: Bozelos P, Vogels TP. Talking science, online. <i>Nature Reviews Neuroscience</i>.
    2021;22(1):1-2. doi:<a href="https://doi.org/10.1038/s41583-020-00408-6">10.1038/s41583-020-00408-6</a>
  apa: Bozelos, P., &#38; Vogels, T. P. (2021). Talking science, online. <i>Nature
    Reviews Neuroscience</i>. Springer Nature. <a href="https://doi.org/10.1038/s41583-020-00408-6">https://doi.org/10.1038/s41583-020-00408-6</a>
  chicago: Bozelos, Panagiotis, and Tim P Vogels. “Talking Science, Online.” <i>Nature
    Reviews Neuroscience</i>. Springer Nature, 2021. <a href="https://doi.org/10.1038/s41583-020-00408-6">https://doi.org/10.1038/s41583-020-00408-6</a>.
  ieee: P. Bozelos and T. P. Vogels, “Talking science, online,” <i>Nature Reviews
    Neuroscience</i>, vol. 22, no. 1. Springer Nature, pp. 1–2, 2021.
  ista: Bozelos P, Vogels TP. 2021. Talking science, online. Nature Reviews Neuroscience.
    22(1), 1–2.
  mla: Bozelos, Panagiotis, and Tim P. Vogels. “Talking Science, Online.” <i>Nature
    Reviews Neuroscience</i>, vol. 22, no. 1, Springer Nature, 2021, pp. 1–2, doi:<a
    href="https://doi.org/10.1038/s41583-020-00408-6">10.1038/s41583-020-00408-6</a>.
  short: P. Bozelos, T.P. Vogels, Nature Reviews Neuroscience 22 (2021) 1–2.
date_created: 2020-11-15T23:01:18Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2025-07-10T12:01:24Z
day: '01'
ddc:
- '570'
department:
- _id: TiVo
doi: 10.1038/s41583-020-00408-6
external_id:
  isi:
  - '000588256300001'
  pmid:
  - '33173190'
file:
- access_level: open_access
  checksum: 7985d7dff94c086e35b94a911d78d9ad
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-04T10:34:22Z
  date_updated: 2021-02-04T10:34:22Z
  file_id: '9088'
  file_name: 2021_NatureNeuroScience_Bozelos.pdf
  file_size: 683634
  relation: main_file
  success: 1
file_date_updated: 2021-02-04T10:34:22Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 1-2
pmid: 1
publication: Nature Reviews Neuroscience
publication_identifier:
  eissn:
  - 1471-0048
  issn:
  - 1471-003X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Talking science, online
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2021'
...
---
_id: '9912'
abstract:
- lang: eng
  text: "In the customary random matrix model for transport in quantum dots with M
    internal degrees of freedom coupled to a chaotic environment via \U0001D441≪\U0001D440
    channels, the density \U0001D70C of transmission eigenvalues is computed from
    a specific invariant ensemble for which explicit formula for the joint probability
    density of all eigenvalues is available. We revisit this problem in the large
    N regime allowing for (i) arbitrary ratio \U0001D719:=\U0001D441/\U0001D440≤1;
    and (ii) general distributions for the matrix elements of the Hamiltonian of the
    quantum dot. In the limit \U0001D719→0, we recover the formula for the density
    \U0001D70C that Beenakker (Rev Mod Phys 69:731–808, 1997) has derived for a special
    matrix ensemble. We also prove that the inverse square root singularity of the
    density at zero and full transmission in Beenakker’s formula persists for any
    \U0001D719<1 but in the borderline case \U0001D719=1 an anomalous \U0001D706−2/3
    singularity arises at zero. To access this level of generality, we develop the
    theory of global and local laws on the spectral density of a large class of noncommutative
    rational expressions in large random matrices with i.i.d. entries."
acknowledgement: The authors are very grateful to Yan Fyodorov for discussions on
  the physical background and for providing references, and to the anonymous referee
  for numerous valuable remarks.
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Torben H
  full_name: Krüger, Torben H
  id: 3020C786-F248-11E8-B48F-1D18A9856A87
  last_name: Krüger
  orcid: 0000-0002-4821-3297
- first_name: Yuriy
  full_name: Nemish, Yuriy
  id: 4D902E6A-F248-11E8-B48F-1D18A9856A87
  last_name: Nemish
  orcid: 0000-0002-7327-856X
citation:
  ama: Erdös L, Krüger TH, Nemish Y. Scattering in quantum dots via noncommutative
    rational functions. <i>Annales Henri Poincaré </i>. 2021;22:4205–4269. doi:<a
    href="https://doi.org/10.1007/s00023-021-01085-6">10.1007/s00023-021-01085-6</a>
  apa: Erdös, L., Krüger, T. H., &#38; Nemish, Y. (2021). Scattering in quantum dots
    via noncommutative rational functions. <i>Annales Henri Poincaré </i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00023-021-01085-6">https://doi.org/10.1007/s00023-021-01085-6</a>
  chicago: Erdös, László, Torben H Krüger, and Yuriy Nemish. “Scattering in Quantum
    Dots via Noncommutative Rational Functions.” <i>Annales Henri Poincaré </i>. Springer
    Nature, 2021. <a href="https://doi.org/10.1007/s00023-021-01085-6">https://doi.org/10.1007/s00023-021-01085-6</a>.
  ieee: L. Erdös, T. H. Krüger, and Y. Nemish, “Scattering in quantum dots via noncommutative
    rational functions,” <i>Annales Henri Poincaré </i>, vol. 22. Springer Nature,
    pp. 4205–4269, 2021.
  ista: Erdös L, Krüger TH, Nemish Y. 2021. Scattering in quantum dots via noncommutative
    rational functions. Annales Henri Poincaré . 22, 4205–4269.
  mla: Erdös, László, et al. “Scattering in Quantum Dots via Noncommutative Rational
    Functions.” <i>Annales Henri Poincaré </i>, vol. 22, Springer Nature, 2021, pp.
    4205–4269, doi:<a href="https://doi.org/10.1007/s00023-021-01085-6">10.1007/s00023-021-01085-6</a>.
  short: L. Erdös, T.H. Krüger, Y. Nemish, Annales Henri Poincaré  22 (2021) 4205–4269.
date_created: 2021-08-15T22:01:29Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2025-04-15T08:04:59Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s00023-021-01085-6
ec_funded: 1
external_id:
  arxiv:
  - '1911.05112'
  isi:
  - '000681531500001'
file:
- access_level: open_access
  checksum: 8d6bac0e2b0a28539608b0538a8e3b38
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-12T12:50:27Z
  date_updated: 2022-05-12T12:50:27Z
  file_id: '11365'
  file_name: 2021_AnnHenriPoincare_Erdoes.pdf
  file_size: 1162454
  relation: main_file
  success: 1
file_date_updated: 2022-05-12T12:50:27Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 4205–4269
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: 'Annales Henri Poincaré '
publication_identifier:
  eissn:
  - 1424-0661
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scattering in quantum dots via noncommutative rational functions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '10414'
abstract:
- lang: eng
  text: 'We consider the almost-sure (a.s.) termination problem for probabilistic
    programs, which are a stochastic extension of classical imperative programs. Lexicographic
    ranking functions provide a sound and practical approach for termination of non-probabilistic
    programs, and their extension to probabilistic programs is achieved via lexicographic
    ranking supermartingales (LexRSMs). However, LexRSMs introduced in the previous
    work have a limitation that impedes their automation: all of their components
    have to be non-negative in all reachable states. This might result in LexRSM not
    existing even for simple terminating programs. Our contributions are twofold:
    First, we introduce a generalization of LexRSMs which allows for some components
    to be negative. This standard feature of non-probabilistic termination proofs
    was hitherto not known to be sound in the probabilistic setting, as the soundness
    proof requires a careful analysis of the underlying stochastic process. Second,
    we present polynomial-time algorithms using our generalized LexRSMs for proving
    a.s. termination in broad classes of linear-arithmetic programs.'
acknowledgement: This research was partially supported by the ERC CoG 863818 (ForM-SMArt),
  the Czech Science Foundation grant No. GJ19-15134Y, and the European Union’s Horizon
  2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement
  No. 665385.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Ehsan
  full_name: Kafshdar Goharshadi, Ehsan
  id: 103b4fa0-896a-11ed-bdf8-87b697bef40d
  last_name: Kafshdar Goharshadi
  orcid: 0000-0002-8595-0587
- first_name: Petr
  full_name: Novotný, Petr
  id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
  last_name: Novotný
- first_name: Jiří
  full_name: Zárevúcky, Jiří
  last_name: Zárevúcky
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
citation:
  ama: 'Chatterjee K, Goharshady E, Novotný P, Zárevúcky J, Zikelic D. On lexicographic
    proof rules for probabilistic termination. In: <i>24th International Symposium
    on Formal Methods</i>. Vol 13047. Springer Nature; 2021:619-639. doi:<a href="https://doi.org/10.1007/978-3-030-90870-6_33">10.1007/978-3-030-90870-6_33</a>'
  apa: 'Chatterjee, K., Goharshady, E., Novotný, P., Zárevúcky, J., &#38; Zikelic,
    D. (2021). On lexicographic proof rules for probabilistic termination. In <i>24th
    International Symposium on Formal Methods</i> (Vol. 13047, pp. 619–639). Virtual:
    Springer Nature. <a href="https://doi.org/10.1007/978-3-030-90870-6_33">https://doi.org/10.1007/978-3-030-90870-6_33</a>'
  chicago: Chatterjee, Krishnendu, Ehsan Goharshady, Petr Novotný, Jiří Zárevúcky,
    and Dorde Zikelic. “On Lexicographic Proof Rules for Probabilistic Termination.”
    In <i>24th International Symposium on Formal Methods</i>, 13047:619–39. Springer
    Nature, 2021. <a href="https://doi.org/10.1007/978-3-030-90870-6_33">https://doi.org/10.1007/978-3-030-90870-6_33</a>.
  ieee: K. Chatterjee, E. Goharshady, P. Novotný, J. Zárevúcky, and D. Zikelic, “On
    lexicographic proof rules for probabilistic termination,” in <i>24th International
    Symposium on Formal Methods</i>, Virtual, 2021, vol. 13047, pp. 619–639.
  ista: 'Chatterjee K, Goharshady E, Novotný P, Zárevúcky J, Zikelic D. 2021. On lexicographic
    proof rules for probabilistic termination. 24th International Symposium on Formal
    Methods. FM: Formal Methods, LNCS, vol. 13047, 619–639.'
  mla: Chatterjee, Krishnendu, et al. “On Lexicographic Proof Rules for Probabilistic
    Termination.” <i>24th International Symposium on Formal Methods</i>, vol. 13047,
    Springer Nature, 2021, pp. 619–39, doi:<a href="https://doi.org/10.1007/978-3-030-90870-6_33">10.1007/978-3-030-90870-6_33</a>.
  short: K. Chatterjee, E. Goharshady, P. Novotný, J. Zárevúcky, D. Zikelic, in:,
    24th International Symposium on Formal Methods, Springer Nature, 2021, pp. 619–639.
conference:
  end_date: 2021-11-26
  location: Virtual
  name: 'FM: Formal Methods'
  start_date: 2021-11-20
date_created: 2021-12-05T23:01:45Z
date_published: 2021-11-10T00:00:00Z
date_updated: 2026-04-07T13:27:55Z
day: '10'
department:
- _id: KrCh
doi: 10.1007/978-3-030-90870-6_33
ec_funded: 1
external_id:
  arxiv:
  - '2108.02188'
  isi:
  - '000758218600033'
intvolume: '     13047'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2108.02188
month: '11'
oa: 1
oa_version: Preprint
page: 619-639
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: 24th International Symposium on Formal Methods
publication_identifier:
  eisbn:
  - 978-3-030-90870-6
  eissn:
  - 1611-3349
  isbn:
  - 9-783-0309-0869-0
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '14778'
    relation: later_version
    status: public
  - id: '14539'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: On lexicographic proof rules for probabilistic termination
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13047
year: '2021'
...
---
_id: '9969'
abstract:
- lang: eng
  text: 'Payment channel networks are a promising approach to improve the scalability
    of cryptocurrencies: they allow to perform transactions in a peer-to-peer fashion,
    along multihop routes in the network, without requiring consensus on the blockchain.
    However, during the discovery of cost-efficient routes for the transaction, critical
    information may be revealed about the transacting entities. This paper initiates
    the study of privacy-preserving route discovery mechanisms for payment channel
    networks. In particular, we present LightPIR, an approach which allows a client
    to learn the shortest (or cheapest in terms of fees) path between two nodes without
    revealing any information about the endpoints of the transaction to the servers.
    The two main observations which allow for an efficient solution in LightPIR are
    that: (1) surprisingly, hub labelling algorithms – which were developed to preprocess
    “street network like” graphs so one can later efficiently compute shortest paths
    – also perform well for the graphs underlying payment channel networks, and that
    (2) hub labelling algorithms can be conveniently combined with private information
    retrieval. LightPIR relies on a simple hub labeling heuristic on top of existing
    hub labeling algorithms which leverages the specific topological features of cryptocurrency
    networks to further minimize storage and bandwidth overheads. In a case study
    considering the Lightning network, we show that our approach is an order of magnitude
    more efficient compared to a privacy-preserving baseline based on using private
    information retrieval on a database that stores all pairs shortest paths.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Iosif
  full_name: Salem, Iosif
  last_name: Salem
- first_name: Stefan
  full_name: Schmid, Stefan
  last_name: Schmid
- first_name: Michelle X
  full_name: Yeo, Michelle X
  id: 2D82B818-F248-11E8-B48F-1D18A9856A87
  last_name: Yeo
  orcid: 0009-0001-3676-4809
citation:
  ama: 'Pietrzak KZ, Salem I, Schmid S, Yeo MX. LightPIR: Privacy-preserving route
    discovery for payment channel networks. In: IEEE; 2021. doi:<a href="https://doi.org/10.23919/IFIPNetworking52078.2021.9472205">10.23919/IFIPNetworking52078.2021.9472205</a>'
  apa: 'Pietrzak, K. Z., Salem, I., Schmid, S., &#38; Yeo, M. X. (2021). LightPIR:
    Privacy-preserving route discovery for payment channel networks. Presented at
    the 2021 IFIP Networking Conference (IFIP Networking), Espoo and Helsinki, Finland:
    IEEE. <a href="https://doi.org/10.23919/IFIPNetworking52078.2021.9472205">https://doi.org/10.23919/IFIPNetworking52078.2021.9472205</a>'
  chicago: 'Pietrzak, Krzysztof Z, Iosif Salem, Stefan Schmid, and Michelle X Yeo.
    “LightPIR: Privacy-Preserving Route Discovery for Payment Channel Networks.” IEEE,
    2021. <a href="https://doi.org/10.23919/IFIPNetworking52078.2021.9472205">https://doi.org/10.23919/IFIPNetworking52078.2021.9472205</a>.'
  ieee: 'K. Z. Pietrzak, I. Salem, S. Schmid, and M. X. Yeo, “LightPIR: Privacy-preserving
    route discovery for payment channel networks,” presented at the 2021 IFIP Networking
    Conference (IFIP Networking), Espoo and Helsinki, Finland, 2021.'
  ista: 'Pietrzak KZ, Salem I, Schmid S, Yeo MX. 2021. LightPIR: Privacy-preserving
    route discovery for payment channel networks. 2021 IFIP Networking Conference
    (IFIP Networking).'
  mla: 'Pietrzak, Krzysztof Z., et al. <i>LightPIR: Privacy-Preserving Route Discovery
    for Payment Channel Networks</i>. IEEE, 2021, doi:<a href="https://doi.org/10.23919/IFIPNetworking52078.2021.9472205">10.23919/IFIPNetworking52078.2021.9472205</a>.'
  short: K.Z. Pietrzak, I. Salem, S. Schmid, M.X. Yeo, in:, IEEE, 2021.
conference:
  end_date: 2021-06-24
  location: Espoo and Helsinki, Finland
  name: 2021 IFIP Networking Conference (IFIP Networking)
  start_date: 2021-06-21
date_created: 2021-08-29T22:01:16Z
date_published: 2021-06-21T00:00:00Z
date_updated: 2026-04-07T13:29:44Z
day: '21'
department:
- _id: KrPi
doi: 10.23919/IFIPNetworking52078.2021.9472205
ec_funded: 1
external_id:
  arxiv:
  - '2104.04293'
  isi:
  - '000853016800008'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2104.04293
month: '06'
oa: 1
oa_version: Submitted Version
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication_identifier:
  eisbn:
  - 978-3-9031-7639-3
  eissn:
  - 1861-2288
  isbn:
  - 978-1-6654-4501-6
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '14506'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: 'LightPIR: Privacy-preserving route discovery for payment channel networks'
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
