---
OA_place: publisher
_id: '11362'
abstract:
- lang: eng
  text: "Deep learning has enabled breakthroughs in challenging computing problems
    and has emerged as the standard problem-solving tool for computer vision and natural
    language processing tasks.\r\nOne exception to this trend is safety-critical tasks
    where robustness and resilience requirements contradict the black-box nature of
    neural networks. \r\nTo deploy deep learning methods for these tasks, it is vital
    to provide guarantees on neural network agents' safety and robustness criteria.
    \r\nThis can be achieved by developing formal verification methods to verify the
    safety and robustness properties of neural networks.\r\n\r\nOur goal is to design,
    develop and assess safety verification methods for neural networks to improve
    their reliability and trustworthiness in real-world applications.\r\nThis thesis
    establishes techniques for the verification of compressed and adversarially trained
    models as well as the design of novel neural networks for verifiably safe decision-making.\r\n\r\nFirst,
    we establish the problem of verifying quantized neural networks. Quantization
    is a technique that trades numerical precision for the computational efficiency
    of running a neural network and is widely adopted in industry.\r\nWe show that
    neglecting the reduced precision when verifying a neural network can lead to wrong
    conclusions about the robustness and safety of the network, highlighting that
    novel techniques for quantized network verification are necessary. We introduce
    several bit-exact verification methods explicitly designed for quantized neural
    networks and experimentally confirm on realistic networks that the network's robustness
    and other formal properties are affected by the quantization.\r\n\r\nFurthermore,
    we perform a case study providing evidence that adversarial training, a standard
    technique for making neural networks more robust, has detrimental effects on the
    network's performance. This robustness-accuracy tradeoff has been studied before
    regarding the accuracy obtained on classification datasets where each data point
    is independent of all other data points. On the other hand, we investigate the
    tradeoff empirically in robot learning settings where a both, a high accuracy
    and a high robustness, are desirable.\r\nOur results suggest that the negative
    side-effects of adversarial training outweigh its robustness benefits in practice.\r\n\r\nFinally,
    we consider the problem of verifying safety when running a Bayesian neural network
    policy in a feedback loop with systems over the infinite time horizon. Bayesian
    neural networks are probabilistic models for learning uncertainties in the data
    and are therefore often used on robotic and healthcare applications where data
    is inherently stochastic.\r\nWe introduce a method for recalibrating Bayesian
    neural networks so that they yield probability distributions over safe decisions
    only.\r\nOur method learns a safety certificate that guarantees safety over the
    infinite time horizon to determine which decisions are safe in every possible
    state of the system.\r\nWe demonstrate the effectiveness of our approach on a
    series of reinforcement learning benchmarks."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Mathias
  full_name: Lechner, Mathias
  id: 3DC22916-F248-11E8-B48F-1D18A9856A87
  last_name: Lechner
citation:
  ama: Lechner M. Learning verifiable representations. 2022. doi:<a href="https://doi.org/10.15479/at:ista:11362">10.15479/at:ista:11362</a>
  apa: Lechner, M. (2022). <i>Learning verifiable representations</i>. Institute of
    Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:11362">https://doi.org/10.15479/at:ista:11362</a>
  chicago: Lechner, Mathias. “Learning Verifiable Representations.” Institute of Science
    and Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:11362">https://doi.org/10.15479/at:ista:11362</a>.
  ieee: M. Lechner, “Learning verifiable representations,” Institute of Science and
    Technology Austria, 2022.
  ista: Lechner M. 2022. Learning verifiable representations. Institute of Science
    and Technology Austria.
  mla: Lechner, Mathias. <i>Learning Verifiable Representations</i>. Institute of
    Science and Technology Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:11362">10.15479/at:ista:11362</a>.
  short: M. Lechner, Learning Verifiable Representations, Institute of Science and
    Technology Austria, 2022.
corr_author: '1'
date_created: 2022-05-12T07:14:01Z
date_published: 2022-05-12T00:00:00Z
date_updated: 2026-07-07T06:49:10Z
day: '12'
ddc:
- '004'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ToHe
doi: 10.15479/at:ista:11362
ec_funded: 1
file:
- access_level: closed
  checksum: 8eefa9c7c10ca7e1a2ccdd731962a645
  content_type: application/zip
  creator: mlechner
  date_created: 2022-05-13T12:33:26Z
  date_updated: 2022-05-13T12:49:00Z
  file_id: '11378'
  file_name: src.zip
  file_size: 13210143
  relation: source_file
- access_level: open_access
  checksum: 1b9e1e5a9a83ed9d89dad2f5133dc026
  content_type: application/pdf
  creator: mlechner
  date_created: 2022-05-16T08:02:28Z
  date_updated: 2022-05-17T15:19:39Z
  file_id: '11382'
  file_name: thesis_main-a2.pdf
  file_size: 2732536
  relation: main_file
file_date_updated: 2022-05-17T15:19:39Z
has_accepted_license: '1'
keyword:
- neural networks
- verification
- machine learning
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nd/4.0/
month: '05'
oa: 1
oa_version: Published Version
page: '124'
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: Formal methods for the design and analysis of complex systems
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication_identifier:
  isbn:
  - 978-3-99078-017-6
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '11366'
    relation: part_of_dissertation
    status: public
  - id: '10665'
    relation: part_of_dissertation
    status: public
  - id: '7808'
    relation: part_of_dissertation
    status: public
  - id: '10666'
    relation: part_of_dissertation
    status: public
  - id: '10667'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
title: Learning verifiable representations
tmp:
  image: /image/cc_by_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
  name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
  short: CC BY-ND (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '22196'
abstract:
- lang: eng
  text: "We explore two questions about pseudo-polynomials, which\r\nare functions
    f : N → Z such that k divides f(n + k) −\r\nf(n) for all n, k. First, for certain
    arbitrarily sparse sets R, we\r\nconstruct pseudo-polynomials f with p|f(n) for
    some n only if\r\np ∈ R. This implies that not all pseudo-polynomials satisfy
    an\r\nassumption of a recent paper of Kowalski and Soundararajan.\r\nWe also consider
    α-primary pseudo-polynomials, where the\r\npseudo-polynomial condition is only
    required for k lying in\r\na set of primes of density α. We show that if an α-primary\r\npseudo-polynomial
    is O(e(β−)n), where β = √7\r\n3 − 1\r\n6 ≈ 0.715,\r\nthen it is a polynomial."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Vivian Zieve
  full_name: Kuperberg, Vivian Zieve
  id: c3bac823-112d-11f0-a3f5-c264f852e697
  last_name: Kuperberg
citation:
  ama: Kuperberg VZ. On pseudo-polynomials divisible only by a sparse set of primes
    and α-primary pseudo-polynomials. <i>Journal of Number Theory</i>. 2022;241:531-541.
    doi:<a href="https://doi.org/10.1016/j.jnt.2022.04.006">10.1016/j.jnt.2022.04.006</a>
  apa: Kuperberg, V. Z. (2022). On pseudo-polynomials divisible only by a sparse set
    of primes and α-primary pseudo-polynomials. <i>Journal of Number Theory</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.jnt.2022.04.006">https://doi.org/10.1016/j.jnt.2022.04.006</a>
  chicago: Kuperberg, Vivian Zieve. “On Pseudo-Polynomials Divisible Only by a Sparse
    Set of Primes and α-Primary Pseudo-Polynomials.” <i>Journal of Number Theory</i>.
    Elsevier, 2022. <a href="https://doi.org/10.1016/j.jnt.2022.04.006">https://doi.org/10.1016/j.jnt.2022.04.006</a>.
  ieee: V. Z. Kuperberg, “On pseudo-polynomials divisible only by a sparse set of
    primes and α-primary pseudo-polynomials,” <i>Journal of Number Theory</i>, vol.
    241. Elsevier, pp. 531–541, 2022.
  ista: Kuperberg VZ. 2022. On pseudo-polynomials divisible only by a sparse set of
    primes and α-primary pseudo-polynomials. Journal of Number Theory. 241, 531–541.
  mla: Kuperberg, Vivian Zieve. “On Pseudo-Polynomials Divisible Only by a Sparse
    Set of Primes and α-Primary Pseudo-Polynomials.” <i>Journal of Number Theory</i>,
    vol. 241, Elsevier, 2022, pp. 531–41, doi:<a href="https://doi.org/10.1016/j.jnt.2022.04.006">10.1016/j.jnt.2022.04.006</a>.
  short: V.Z. Kuperberg, Journal of Number Theory 241 (2022) 531–541.
date_created: 2026-06-29T12:58:07Z
date_published: 2022-05-18T00:00:00Z
date_updated: 2026-07-14T11:08:14Z
day: '18'
doi: 10.1016/j.jnt.2022.04.006
extern: '1'
external_id:
  arxiv:
  - '2006.02527'
intvolume: '       241'
keyword:
- Pseudo-polynomials
- Chinese remainder theorem
- Ruzsa’s conjecture
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2006.02527
month: '05'
oa: 1
oa_version: Preprint
page: 531-541
publication: Journal of Number Theory
publication_identifier:
  issn:
  - 0022-314X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: On pseudo-polynomials divisible only by a sparse set of primes and α-primary
  pseudo-polynomials
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 241
year: '2022'
...
---
OA_place: repository
_id: '18293'
abstract:
- lang: eng
  text: Given a non-singular diagonal cubic hypersurface X⊂Pn−1 over Fq(t) with char(Fq)≠3,
    we show that the number of rational points of height at most |P| is O(|P|3+ε)
    for n=6 and O(|P|2+ε) for n=4. In fact, if n=4 and char(Fq)>3 we prove that the
    number of rational points away from any rational line contained in X is bounded
    by O(|P|3/2+ε). From the result in 6 variables we deduce weak approximation for
    diagonal cubic hypersurfaces for n≥7 over Fq(t) when char(Fq)>3 and handle Waring's
    problem for cubes in 7 variables over Fq(t) when char(Fq)≠3. Our results answer
    a question of Davenport regarding the number of solutions of bounded height to
    x31+x32+x33=x34+x35+x36 with xi∈Fq[t].
article_number: '2208.05422'
article_processing_charge: No
arxiv: 1
author:
- first_name: Jakob
  full_name: Glas, Jakob
  id: d6423cba-dc74-11ea-a0a7-ee61689ff5fb
  last_name: Glas
- first_name: Leonhard
  full_name: Hochfilzer, Leonhard
  last_name: Hochfilzer
citation:
  ama: Glas J, Hochfilzer L. On a question of Davenport and diagonal cubic forms over
    Fq(t). <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2208.05422">10.48550/arXiv.2208.05422</a>
  apa: Glas, J., &#38; Hochfilzer, L. (n.d.). On a question of Davenport and diagonal
    cubic forms over Fq(t). <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2208.05422">https://doi.org/10.48550/arXiv.2208.05422</a>
  chicago: Glas, Jakob, and Leonhard Hochfilzer. “On a Question of Davenport and Diagonal
    Cubic Forms over Fq(T).” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2208.05422">https://doi.org/10.48550/arXiv.2208.05422</a>.
  ieee: J. Glas and L. Hochfilzer, “On a question of Davenport and diagonal cubic
    forms over Fq(t),” <i>arXiv</i>. .
  ista: Glas J, Hochfilzer L. On a question of Davenport and diagonal cubic forms
    over Fq(t). arXiv, 2208.05422.
  mla: Glas, Jakob, and Leonhard Hochfilzer. “On a Question of Davenport and Diagonal
    Cubic Forms over Fq(T).” <i>ArXiv</i>, 2208.05422, doi:<a href="https://doi.org/10.48550/arXiv.2208.05422">10.48550/arXiv.2208.05422</a>.
  short: J. Glas, L. Hochfilzer, ArXiv (n.d.).
corr_author: '1'
date_created: 2024-10-10T12:46:41Z
date_published: 2022-08-10T00:00:00Z
date_updated: 2026-07-16T09:10:28Z
day: '10'
department:
- _id: TiBr
doi: 10.48550/arXiv.2208.05422
external_id:
  arxiv:
  - '2208.05422'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2208.05422
month: '08'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '18132'
    relation: dissertation_contains
    status: public
  - id: '18705'
    relation: later_version
    status: public
status: public
title: On a question of Davenport and diagonal cubic forms over Fq(t)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12244'
abstract:
- lang: eng
  text: Environmental cues influence the highly dynamic morphology of microglia. Strategies
    to characterize these changes usually involve user-selected morphometric features,
    which preclude the identification of a spectrum of context-dependent morphological
    phenotypes. Here we develop MorphOMICs, a topological data analysis approach,
    which enables semiautomatic mapping of microglial morphology into an atlas of
    cue-dependent phenotypes and overcomes feature-selection biases and biological
    variability. We extract spatially heterogeneous and sexually dimorphic morphological
    phenotypes for seven adult mouse brain regions. This sex-specific phenotype declines
    with maturation but increases over the disease trajectories in two neurodegeneration
    mouse models, with females showing a faster morphological shift in affected brain
    regions. Remarkably, microglia morphologies reflect an adaptation upon repeated
    exposure to ketamine anesthesia and do not recover to control morphologies. Finally,
    we demonstrate that both long primary processes and short terminal processes provide
    distinct insights to morphological phenotypes. MorphOMICs opens a new perspective
    to characterize microglial morphology.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
- _id: ScienComp
acknowledgement: We thank the scientific service units at ISTA, in particular M. Schunn’s
  team at the preclinical facility, and especially our colony manager S. Haslinger,
  for excellent support. We are also grateful to the ISTA Imaging & Optics Facility,
  and in particular C. Sommer for helping with the data file conversions. We thank
  R. Erhart from the ISTA Scientific Computing Unit for improving the script performance.
  We thank M. Maes, B. Nagy, S. Oakeley and M. Benevento and all members of the Siegert
  group for constant feedback on the project and on the manuscript. This research
  was supported by the European Union Horizon 2020 research and innovation program
  under the Marie Skłodowska-Curie Actions program (754411 to R.J.A.C.), and by the
  European Research Council (grant no. 715571 to S.S.). L.K. was supported by funding
  to the Blue Brain Project, a research center of the École polytechnique fédérale
  de Lausanne, from the Swiss government’s ETH Board of the Swiss Federal Institutes
  of Technology. L.-H.T. was supported by NIH (grant no. R37NS051874) and by the JPB
  Foundation. The funders had no role in study design, data collection and analysis,
  decision to publish or preparation of the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Gloria
  full_name: Colombo, Gloria
  id: 3483CF6C-F248-11E8-B48F-1D18A9856A87
  last_name: Colombo
  orcid: 0000-0001-9434-8902
- first_name: Ryan J
  full_name: Cubero, Ryan J
  id: 850B2E12-9CD4-11E9-837F-E719E6697425
  last_name: Cubero
  orcid: 0000-0003-0002-1867
- first_name: Lida
  full_name: Kanari, Lida
  last_name: Kanari
- first_name: Alessandro
  full_name: Venturino, Alessandro
  id: 41CB84B2-F248-11E8-B48F-1D18A9856A87
  last_name: Venturino
  orcid: 0000-0003-2356-9403
- first_name: Rouven
  full_name: Schulz, Rouven
  id: 4C5E7B96-F248-11E8-B48F-1D18A9856A87
  last_name: Schulz
  orcid: 0000-0001-5297-733X
- first_name: Martina
  full_name: Scolamiero, Martina
  last_name: Scolamiero
- first_name: Jens
  full_name: Agerberg, Jens
  last_name: Agerberg
- first_name: Hansruedi
  full_name: Mathys, Hansruedi
  last_name: Mathys
- first_name: Li-Huei
  full_name: Tsai, Li-Huei
  last_name: Tsai
- first_name: Wojciech
  full_name: Chachólski, Wojciech
  last_name: Chachólski
- first_name: Kathryn
  full_name: Hess, Kathryn
  last_name: Hess
- first_name: Sandra
  full_name: Siegert, Sandra
  id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
  last_name: Siegert
  orcid: 0000-0001-8635-0877
citation:
  ama: Colombo G, Cubero RJ, Kanari L, et al. A tool for mapping microglial morphology,
    morphOMICs, reveals brain-region and sex-dependent phenotypes. <i>Nature Neuroscience</i>.
    2022;25(10):1379-1393. doi:<a href="https://doi.org/10.1038/s41593-022-01167-6">10.1038/s41593-022-01167-6</a>
  apa: Colombo, G., Cubero, R. J., Kanari, L., Venturino, A., Schulz, R., Scolamiero,
    M., … Siegert, S. (2022). A tool for mapping microglial morphology, morphOMICs,
    reveals brain-region and sex-dependent phenotypes. <i>Nature Neuroscience</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41593-022-01167-6">https://doi.org/10.1038/s41593-022-01167-6</a>
  chicago: Colombo, Gloria, Ryan J Cubero, Lida Kanari, Alessandro Venturino, Rouven
    Schulz, Martina Scolamiero, Jens Agerberg, et al. “A Tool for Mapping Microglial
    Morphology, MorphOMICs, Reveals Brain-Region and Sex-Dependent Phenotypes.” <i>Nature
    Neuroscience</i>. Springer Nature, 2022. <a href="https://doi.org/10.1038/s41593-022-01167-6">https://doi.org/10.1038/s41593-022-01167-6</a>.
  ieee: G. Colombo <i>et al.</i>, “A tool for mapping microglial morphology, morphOMICs,
    reveals brain-region and sex-dependent phenotypes,” <i>Nature Neuroscience</i>,
    vol. 25, no. 10. Springer Nature, pp. 1379–1393, 2022.
  ista: Colombo G, Cubero RJ, Kanari L, Venturino A, Schulz R, Scolamiero M, Agerberg
    J, Mathys H, Tsai L-H, Chachólski W, Hess K, Siegert S. 2022. A tool for mapping
    microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes.
    Nature Neuroscience. 25(10), 1379–1393.
  mla: Colombo, Gloria, et al. “A Tool for Mapping Microglial Morphology, MorphOMICs,
    Reveals Brain-Region and Sex-Dependent Phenotypes.” <i>Nature Neuroscience</i>,
    vol. 25, no. 10, Springer Nature, 2022, pp. 1379–93, doi:<a href="https://doi.org/10.1038/s41593-022-01167-6">10.1038/s41593-022-01167-6</a>.
  short: G. Colombo, R.J. Cubero, L. Kanari, A. Venturino, R. Schulz, M. Scolamiero,
    J. Agerberg, H. Mathys, L.-H. Tsai, W. Chachólski, K. Hess, S. Siegert, Nature
    Neuroscience 25 (2022) 1379–1393.
corr_author: '1'
date_created: 2023-01-16T09:53:07Z
date_published: 2022-10-01T00:00:00Z
date_updated: 2026-07-21T22:30:09Z
day: '01'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1038/s41593-022-01167-6
ec_funded: 1
external_id:
  isi:
  - '000862214700001'
  pmid:
  - '36180790'
file:
- access_level: open_access
  checksum: 28431146873096f52e0107b534f178c9
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T08:06:56Z
  date_updated: 2023-01-30T08:06:56Z
  file_id: '12437'
  file_name: 2022_NatureNeuroscience_Colombo.pdf
  file_size: 23789835
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T08:06:56Z
has_accepted_license: '1'
intvolume: '        25'
isi: 1
issue: '10'
keyword:
- General Neuroscience
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 1379-1393
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: 25D4A630-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '715571'
  name: Microglia action towards neuronal circuit formation and function in health
    and disease
publication: Nature Neuroscience
publication_identifier:
  eissn:
  - 1546-1726
  issn:
  - 1097-6256
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/morphomics-revealing-the-hidden-meaning-of-microglia-shape/
  record:
  - id: '12378'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: A tool for mapping microglial morphology, morphOMICs, reveals brain-region
  and sex-dependent phenotypes
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 25
year: '2022'
...
---
OA_place: publisher
_id: '11388'
abstract:
- lang: eng
  text: "In evolve and resequence experiments, a population is sequenced, subjected
    to selection and\r\nthen sequenced again, so that genetic changes before and after
    selection can be observed at\r\nthe genetic level. Here, I use these studies to
    better understand the genetic basis of complex\r\ntraits - traits which depend
    on more than a few genes.\r\nIn the first chapter, I discuss the first evolve
    and resequence experiment, in which a population\r\nof mice, the so-called \"Longshanks\"
    mice, were selected for tibia length while their body mass\r\nwas kept constant.
    The full pedigree is known. We observed a selection response on all\r\nchromosomes
    and used the infinitesimal model with linkage, a model which assumes an infinite\r\nnumber
    of genes with infinitesimally small effect sizes, as a null model. Results implied
    a very\r\npolygenic basis with a few loci of major effect standing out and changing
    in parallel. There\r\nwas large variability between the different chromosomes
    in this study, probably due to LD.\r\nIn chapter two, I go on to discuss the impact
    of LD, on the variability in an allele-frequency\r\nbased summary statistic, giving
    an equation based on the initial allele frequencies, average\r\npairwise LD, and
    the first four moments of the haplotype block copy number distribution. I\r\ndescribe
    this distribution by referring back to the founder generation. I then demonstrate\r\nhow
    to infer selection via a maximum likelihood scheme on the example of a single
    locus and\r\ndiscuss how to extend this to more realistic scenarios.\r\nIn chapter
    three, I discuss the second evolve and resequence experiment, in which a small\r\npopulation
    of Drosophila melanogaster was selected for increased pupal case size over 6\r\ngenerations.
    The experiment was highly replicated with 27 lines selected within family and
    a\r\nknown pedigree. We observed a phenotypic selection response of over one standard
    deviation.\r\nI describe the patterns in allele frequency data, including allele
    frequency changes and patterns\r\nof heterozygosity, and give ideas for future
    work."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Stefanie
  full_name: Belohlavy, Stefanie
  id: 43FE426A-F248-11E8-B48F-1D18A9856A87
  last_name: Belohlavy
  orcid: 0000-0002-9849-498X
citation:
  ama: Belohlavy S. The genetic basis of complex traits studied via analysis of evolve
    and resequence experiments. 2022. doi:<a href="https://doi.org/10.15479/at:ista:11388">10.15479/at:ista:11388</a>
  apa: Belohlavy, S. (2022). <i>The genetic basis of complex traits studied via analysis
    of evolve and resequence experiments</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/at:ista:11388">https://doi.org/10.15479/at:ista:11388</a>
  chicago: Belohlavy, Stefanie. “The Genetic Basis of Complex Traits Studied via Analysis
    of Evolve and Resequence Experiments.” Institute of Science and Technology Austria,
    2022. <a href="https://doi.org/10.15479/at:ista:11388">https://doi.org/10.15479/at:ista:11388</a>.
  ieee: S. Belohlavy, “The genetic basis of complex traits studied via analysis of
    evolve and resequence experiments,” Institute of Science and Technology Austria,
    2022.
  ista: Belohlavy S. 2022. The genetic basis of complex traits studied via analysis
    of evolve and resequence experiments. Institute of Science and Technology Austria.
  mla: Belohlavy, Stefanie. <i>The Genetic Basis of Complex Traits Studied via Analysis
    of Evolve and Resequence Experiments</i>. Institute of Science and Technology
    Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:11388">10.15479/at:ista:11388</a>.
  short: S. Belohlavy, The Genetic Basis of Complex Traits Studied via Analysis of
    Evolve and Resequence Experiments, Institute of Science and Technology Austria,
    2022.
corr_author: '1'
date_created: 2022-05-16T16:49:18Z
date_published: 2022-05-18T00:00:00Z
date_updated: 2026-04-07T14:29:57Z
day: '18'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: GradSch
- _id: NiBa
doi: 10.15479/at:ista:11388
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  date_created: 2022-05-19T13:07:47Z
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file_date_updated: 2023-05-20T22:30:03Z
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language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '98'
publication_identifier:
  isbn:
  - 978-3-99078-018-3
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '6713'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
title: The genetic basis of complex traits studied via analysis of evolve and resequence
  experiments
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2022'
...
---
OA_place: repository
_id: '11943'
abstract:
- lang: eng
  text: Complex wiring between neurons underlies the information-processing network
    enabling all brain functions, including cognition and memory. For understanding
    how the network is structured, processes information, and changes over time, comprehensive
    visualization of the architecture of living brain tissue with its cellular and
    molecular components would open up major opportunities. However, electron microscopy
    (EM) provides nanometre-scale resolution required for full <jats:italic>in-silico</jats:italic>
    reconstruction<jats:sup>1–5</jats:sup>, yet is limited to fixed specimens and
    static representations. Light microscopy allows live observation, with super-resolution
    approaches<jats:sup>6–12</jats:sup> facilitating nanoscale visualization, but
    comprehensive 3D-reconstruction of living brain tissue has been hindered by tissue
    photo-burden, photobleaching, insufficient 3D-resolution, and inadequate signal-to-noise
    ratio (SNR). Here we demonstrate saturated reconstruction of living brain tissue.
    We developed an integrated imaging and analysis technology, adapting stimulated
    emission depletion (STED) microscopy<jats:sup>6,13</jats:sup> in extracellularly
    labelled tissue<jats:sup>14</jats:sup> for high SNR and near-isotropic resolution.
    Centrally, a two-stage deep-learning approach leveraged previously obtained information
    on sample structure to drastically reduce photo-burden and enable automated volumetric
    reconstruction down to single synapse level. Live reconstruction provides unbiased
    analysis of tissue architecture across time in relation to functional activity
    and targeted activation, and contextual understanding of molecular labelling.
    This adoptable technology will facilitate novel insights into the dynamic functional
    architecture of living brain tissue.
article_processing_charge: No
author:
- first_name: Philipp
  full_name: Velicky, Philipp
  id: 39BDC62C-F248-11E8-B48F-1D18A9856A87
  last_name: Velicky
  orcid: 0000-0002-2340-7431
- first_name: Eder
  full_name: Miguel Villalba, Eder
  id: 3FB91342-F248-11E8-B48F-1D18A9856A87
  last_name: Miguel Villalba
  orcid: 0000-0001-5665-0430
- first_name: Julia M
  full_name: Michalska, Julia M
  id: 443DB6DE-F248-11E8-B48F-1D18A9856A87
  last_name: Michalska
  orcid: 0000-0003-3862-1235
- first_name: Donglai
  full_name: Wei, Donglai
  last_name: Wei
- first_name: Zudi
  full_name: Lin, Zudi
  last_name: Lin
- first_name: Jake
  full_name: Watson, Jake
  id: 63836096-4690-11EA-BD4E-32803DDC885E
  last_name: Watson
  orcid: 0000-0002-8698-3823
- first_name: Jakob
  full_name: Troidl, Jakob
  last_name: Troidl
- first_name: Johanna
  full_name: Beyer, Johanna
  last_name: Beyer
- first_name: Yoav
  full_name: Ben Simon, Yoav
  id: 43DF3136-F248-11E8-B48F-1D18A9856A87
  last_name: Ben Simon
- first_name: Christoph M
  full_name: Sommer, Christoph M
  id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
  last_name: Sommer
  orcid: 0000-0003-1216-9105
- first_name: Wiebke
  full_name: Jahr, Wiebke
  id: 425C1CE8-F248-11E8-B48F-1D18A9856A87
  last_name: Jahr
  orcid: 0000-0003-0201-2315
- first_name: Alban
  full_name: Cenameri, Alban
  id: 9ac8f577-2357-11eb-997a-e566c5550886
  last_name: Cenameri
- first_name: Johannes
  full_name: Broichhagen, Johannes
  last_name: Broichhagen
- first_name: Seth G. N.
  full_name: Grant, Seth G. N.
  last_name: Grant
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: Hanspeter
  full_name: Pfister, Hanspeter
  last_name: Pfister
- first_name: Bernd
  full_name: Bickel, Bernd
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
citation:
  ama: Velicky P, Miguel Villalba E, Michalska JM, et al. Saturated reconstruction
    of living brain tissue. <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2022.03.16.484431">10.1101/2022.03.16.484431</a>
  apa: Velicky, P., Miguel Villalba, E., Michalska, J. M., Wei, D., Lin, Z., Watson,
    J., … Danzl, J. G. (n.d.). Saturated reconstruction of living brain tissue. <i>bioRxiv</i>.
    <a href="https://doi.org/10.1101/2022.03.16.484431">https://doi.org/10.1101/2022.03.16.484431</a>
  chicago: Velicky, Philipp, Eder Miguel Villalba, Julia M Michalska, Donglai Wei,
    Zudi Lin, Jake Watson, Jakob Troidl, et al. “Saturated Reconstruction of Living
    Brain Tissue.” <i>BioRxiv</i>, n.d. <a href="https://doi.org/10.1101/2022.03.16.484431">https://doi.org/10.1101/2022.03.16.484431</a>.
  ieee: P. Velicky <i>et al.</i>, “Saturated reconstruction of living brain tissue,”
    <i>bioRxiv</i>. .
  ista: Velicky P, Miguel Villalba E, Michalska JM, Wei D, Lin Z, Watson J, Troidl
    J, Beyer J, Ben Simon Y, Sommer CM, Jahr W, Cenameri A, Broichhagen J, Grant SGN,
    Jonas PM, Novarino G, Pfister H, Bickel B, Danzl JG. Saturated reconstruction
    of living brain tissue. bioRxiv, <a href="https://doi.org/10.1101/2022.03.16.484431">10.1101/2022.03.16.484431</a>.
  mla: Velicky, Philipp, et al. “Saturated Reconstruction of Living Brain Tissue.”
    <i>BioRxiv</i>, doi:<a href="https://doi.org/10.1101/2022.03.16.484431">10.1101/2022.03.16.484431</a>.
  short: P. Velicky, E. Miguel Villalba, J.M. Michalska, D. Wei, Z. Lin, J. Watson,
    J. Troidl, J. Beyer, Y. Ben Simon, C.M. Sommer, W. Jahr, A. Cenameri, J. Broichhagen,
    S.G.N. Grant, P.M. Jonas, G. Novarino, H. Pfister, B. Bickel, J.G. Danzl, BioRxiv
    (n.d.).
corr_author: '1'
das_tickbox: '1'
date_created: 2022-08-23T11:07:59Z
date_published: 2022-05-09T00:00:00Z
date_updated: 2026-07-21T22:31:05Z
day: '09'
department:
- _id: PeJo
- _id: GaNo
- _id: BeBi
- _id: JoDa
doi: 10.1101/2022.03.16.484431
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2022.03.16.484431
month: '05'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: draft
related_material:
  record:
  - id: '13267'
    relation: later_version
    status: public
  - id: '12470'
    relation: dissertation_contains
    status: public
status: public
title: Saturated reconstruction of living brain tissue
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '11498'
abstract:
- lang: eng
  text: Rest-frame ultraviolet (UV) emission lines probe electron densities, gas-phase
    abundances, metallicities, and ionization parameters of the emitting star-forming
    galaxies and their environments. The strongest main UV emission line, Lyα, has
    been instrumental in advancing the general knowledge of galaxy formation in the
    early universe. However, observing Lyα emission becomes increasingly challenging
    at z ≳ 6 when the neutral hydrogen fraction of the circumgalactic and intergalactic
    media increases. Secondary weaker UV emission lines provide important alternative
    methods for studying galaxy properties at high redshift. We present a large sample
    of rest-frame UV emission line sources at intermediate redshift for calibrating
    and exploring the connection between secondary UV lines and the emitting galaxies’
    physical properties and their Lyα emission. The sample of 2052 emission line sources
    with 1.5 < z < 6.4 was collected from integral field data from the MUSE-Wide and
    MUSE-Deep surveys taken as part of Guaranteed Time Observations. The objects were
    selected through untargeted source detection (i.e., no preselection of sources
    as in dedicated spectroscopic campaigns) in the three-dimensional MUSE data cubes.
    We searched optimally extracted one-dimensional spectra of the full sample for
    UV emission features via emission line template matching, resulting in a sample
    of more than 100 rest-frame UV emission line detections. We show that the detection
    efficiency of (non-Lyα) UV emission lines increases with survey depth, and that
    the emission line strength of He IIλ1640 Å, [O III] λ1661 + O III] λ1666, and
    [Si III] λ1883 + Si III] λ1892 correlate with the strength of [C III] λ1907 +
    C III] λ1909. The rest-frame equivalent width (EW0) of [C III] λ1907 + C III]
    λ1909 is found to be roughly 0.22 ± 0.18 of EW0(Lyα). We measured the velocity
    offsets of resonant emission lines with respect to systemic tracers. For C IVλ1548
    + C IVλ1551 we find that ΔvC IV ≲ 250 km s−1, whereas ΔvLyα falls in the range
    of 250−500 km s−1 which is in agreement with previous results from the literature.
    The electron density ne measured from [Si III] λ1883 + Si III] λ1892 and [C III]
    λ1907 + C III] λ1909 line flux ratios is generally < 105 cm−3 and the gas-phase
    abundance is below solar at 12 + log10(O/H)≈8. Lastly, we used “PhotoIonization
    Model Probability Density Functions” to infer physical parameters of the full
    sample and individual systems based on photoionization model parameter grids and
    observational constraints from our UV emission line searches. This reveals that
    the UV line emitters generally have ionization parameter log10(U) ≈ −2.5 and metal
    mass fractions that scatter around Z ≈ 10−2, that is Z ≈ 0.66 Z⊙. Value-added
    catalogs of the full sample of MUSE objects studied in this work and a collection
    of UV line emitters from the literature are provided with this paper.
acknowledgement: 'We would like to thank Charlotte Mason for useful discussions and
  for providing the data for the curves shown in Fig. 13 and Dawn Erb for providing
  the observational data for the comparison sample studied by Steidel et al. (2014),
  also shown in Fig. 13. This work has been supported by the BMBF grant 05A14BAC and
  we acknowledge support by the Competitive Fund of the Leibniz Association through
  grant SAW-2015-AIP-2. AF acknowledges the support from grant PRIN MIUR2017-20173ML3WW_001.
  JS acknowledges the support from Vici grant 639.043.409 from the Dutch Research
  Council (NWO). GM received funding from the European Union’s Horizon 2020 research
  and innovation programme under the Marie Sklodowska-Curie grant agreement No MARACAS
  – DLV-896778. This paper is based on observations collected at the European Organisation
  for Astronomical Research in the Southern Hemisphere under ESO programmes 094.A-0289(B),
  095.A-0010(A), 096.A-0045(A), 096.A-0045(B), 094.A-0205, 095.A-0240, 096.A-0090,
  097.A-0160, and 098.A-0017. This paper also makes use of observations made with
  the NASA/ESA Hubble Space Telescope obtained at STScI. This research made use of
  the following programs and open-source packages for Python and we are thankful to
  their developers: DS9 (Joye & Mandel 2003), Astropy (Astropy Collaboration 2013,
  2018), APLpy (Robitaille & Bressert 2012), iPython (Pérez & Granger 2007), numpy
  (van der Walt et al. 2011), matplotlib (Hunter 2007), and SciPy (Jones et al. 2001).'
article_number: A80
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: K. B.
  full_name: Schmidt, K. B.
  last_name: Schmidt
- first_name: J.
  full_name: Kerutt, J.
  last_name: Kerutt
- first_name: L.
  full_name: Wisotzki, L.
  last_name: Wisotzki
- first_name: T.
  full_name: Urrutia, T.
  last_name: Urrutia
- first_name: A.
  full_name: Feltre, A.
  last_name: Feltre
- first_name: M. V.
  full_name: Maseda, M. V.
  last_name: Maseda
- first_name: T.
  full_name: Nanayakkara, T.
  last_name: Nanayakkara
- first_name: R.
  full_name: Bacon, R.
  last_name: Bacon
- first_name: L. A.
  full_name: Boogaard, L. A.
  last_name: Boogaard
- first_name: S.
  full_name: Conseil, S.
  last_name: Conseil
- first_name: T.
  full_name: Contini, T.
  last_name: Contini
- first_name: E. C.
  full_name: Herenz, E. C.
  last_name: Herenz
- first_name: W.
  full_name: Kollatschny, W.
  last_name: Kollatschny
- first_name: M.
  full_name: Krumpe, M.
  last_name: Krumpe
- first_name: F.
  full_name: Leclercq, F.
  last_name: Leclercq
- first_name: G.
  full_name: Mahler, G.
  last_name: Mahler
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: V.
  full_name: Mauerhofer, V.
  last_name: Mauerhofer
- first_name: J.
  full_name: Richard, J.
  last_name: Richard
- first_name: J.
  full_name: Schaye, J.
  last_name: Schaye
citation:
  ama: Schmidt KB, Kerutt J, Wisotzki L, et al. Recovery and analysis of rest-frame
    UV emission lines in 2052 galaxies observed with MUSE at 1.5 &#60; z &#60; 6.4.
    <i>Astronomy &#38; Astrophysics</i>. 2021;654. doi:<a href="https://doi.org/10.1051/0004-6361/202140876">10.1051/0004-6361/202140876</a>
  apa: Schmidt, K. B., Kerutt, J., Wisotzki, L., Urrutia, T., Feltre, A., Maseda,
    M. V., … Schaye, J. (2021). Recovery and analysis of rest-frame UV emission lines
    in 2052 galaxies observed with MUSE at 1.5 &#60; z &#60; 6.4. <i>Astronomy &#38;
    Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202140876">https://doi.org/10.1051/0004-6361/202140876</a>
  chicago: Schmidt, K. B., J. Kerutt, L. Wisotzki, T. Urrutia, A. Feltre, M. V. Maseda,
    T. Nanayakkara, et al. “Recovery and Analysis of Rest-Frame UV Emission Lines
    in 2052 Galaxies Observed with MUSE at 1.5 &#60; z &#60; 6.4.” <i>Astronomy &#38;
    Astrophysics</i>. EDP Sciences, 2021. <a href="https://doi.org/10.1051/0004-6361/202140876">https://doi.org/10.1051/0004-6361/202140876</a>.
  ieee: K. B. Schmidt <i>et al.</i>, “Recovery and analysis of rest-frame UV emission
    lines in 2052 galaxies observed with MUSE at 1.5 &#60; z &#60; 6.4,” <i>Astronomy
    &#38; Astrophysics</i>, vol. 654. EDP Sciences, 2021.
  ista: Schmidt KB, Kerutt J, Wisotzki L, Urrutia T, Feltre A, Maseda MV, Nanayakkara
    T, Bacon R, Boogaard LA, Conseil S, Contini T, Herenz EC, Kollatschny W, Krumpe
    M, Leclercq F, Mahler G, Matthee JJ, Mauerhofer V, Richard J, Schaye J. 2021.
    Recovery and analysis of rest-frame UV emission lines in 2052 galaxies observed
    with MUSE at 1.5 &#60; z &#60; 6.4. Astronomy &#38; Astrophysics. 654, A80.
  mla: Schmidt, K. B., et al. “Recovery and Analysis of Rest-Frame UV Emission Lines
    in 2052 Galaxies Observed with MUSE at 1.5 &#60; z &#60; 6.4.” <i>Astronomy &#38;
    Astrophysics</i>, vol. 654, A80, EDP Sciences, 2021, doi:<a href="https://doi.org/10.1051/0004-6361/202140876">10.1051/0004-6361/202140876</a>.
  short: K.B. Schmidt, J. Kerutt, L. Wisotzki, T. Urrutia, A. Feltre, M.V. Maseda,
    T. Nanayakkara, R. Bacon, L.A. Boogaard, S. Conseil, T. Contini, E.C. Herenz,
    W. Kollatschny, M. Krumpe, F. Leclercq, G. Mahler, J.J. Matthee, V. Mauerhofer,
    J. Richard, J. Schaye, Astronomy &#38; Astrophysics 654 (2021).
date_created: 2022-07-06T08:49:03Z
date_published: 2021-10-15T00:00:00Z
date_updated: 2022-07-19T09:34:36Z
day: '15'
doi: 10.1051/0004-6361/202140876
extern: '1'
external_id:
  arxiv:
  - '2108.01713'
intvolume: '       654'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- 'ultraviolet: galaxies / galaxies: high-redshift / galaxies: ISM / ISM: lines and
  bands / methods: observational / techniques: imaging spectroscopy'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2108.01713
month: '10'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Recovery and analysis of rest-frame UV emission lines in 2052 galaxies observed
  with MUSE at 1.5 < z < 6.4
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 654
year: '2021'
...
---
_id: '11500'
abstract:
- lang: eng
  text: We report the discovery of diffuse extended Lyα emission from redshift 3.1
    to 4.5, tracing cosmic web filaments on scales of 2.5−4 cMpc. These structures
    have been observed in overdensities of Lyα emitters in the MUSE Extremely Deep
    Field, a 140 h deep MUSE observation located in the Hubble Ultra-Deep Field. Among
    the 22 overdense regions identified, five are likely to harbor very extended Lyα
    emission at high significance with an average surface brightness of 5 × 10−20
    erg s−1 cm−2 arcsec−2. Remarkably, 70% of the total Lyα luminosity from these
    filaments comes from beyond the circumgalactic medium of any identified Lyα emitter.
    Fluorescent Lyα emission powered by the cosmic UV background can only account
    for less than 34% of this emission at z ≈ 3 and for not more than 10% at higher
    redshift. We find that the bulk of this diffuse emission can be reproduced by
    the unresolved Lyα emission of a large population of ultra low-luminosity Lyα
    emitters (< 1040 erg s−1), provided that the faint end of the Lyα luminosity function
    is steep (α ⪅ −1.8), it extends down to luminosities lower than 1038 − 1037 erg
    s−1, and the clustering of these Lyα emitters is significant (filling factor <
    1/6). If these Lyα emitters are powered by star formation, then this implies their
    luminosity function needs to extend down to star formation rates < 10−4 M⊙ yr−1.
    These observations provide the first detection of the cosmic web in Lyα emission
    in typical filamentary environments and the first observational clue indicating
    the existence of a large population of ultra low-luminosity Lyα emitters at high
    redshift.
acknowledgement: 'We warmly thank ESO Paranal staff for their great professional support
  during all MXDF GTO observing runs. We thank the anonymous referee for a careful
  reading of the manuscript and helpful comments. We also thank Matthew Lehnert for
  fruitful discussions. RB, AF, SC acknowledge support from the ERC advanced grant
  339659-MUSICOS. JB acknowledges support by Fundação para a Ciência e a Tecnologia
  (FCT) through the research grants UID/FIS/04434/2019, UIDB/04434/2020, UIDP/04434/2020
  and through the Investigador FCT Contract No. IF/01654/2014/CP1215/CT0003. TG, AV
  acknowledges support from the European Research Council under grant agreement ERC-stg-757258
  (TRIPLE). DM acknowledges A. Dabbech for useful interactions about IUWT and support
  from the GDR ISIS through the Projets exploratoires program (project TASTY). AF
  acknowledges the support from grant PRIN MIUR2017-20173ML3WW_001. SLZ acknowledges
  support by The Netherlands Organisation for Scientific Research (NWO) through a
  TOP Grant Module 1 under project number 614.001.652. This research made use of the
  following open-source software and we are thankful to the developers of these: GNU
  Octave (Eaton et al. 2018) and its statistics, signal and image packages, the Python
  packages Matplotlib (Hunter 2007), Numpy (van der Walt et al. 2010), MPDAF (Piqueras
  et al. 2017), Astropy (Astropy Collaboration 2018), PyWavelets (Lee et al. 2019).'
article_number: A107
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: R.
  full_name: Bacon, R.
  last_name: Bacon
- first_name: D.
  full_name: Mary, D.
  last_name: Mary
- first_name: T.
  full_name: Garel, T.
  last_name: Garel
- first_name: J.
  full_name: Blaizot, J.
  last_name: Blaizot
- first_name: M.
  full_name: Maseda, M.
  last_name: Maseda
- first_name: J.
  full_name: Schaye, J.
  last_name: Schaye
- first_name: L.
  full_name: Wisotzki, L.
  last_name: Wisotzki
- first_name: S.
  full_name: Conseil, S.
  last_name: Conseil
- first_name: J.
  full_name: Brinchmann, J.
  last_name: Brinchmann
- first_name: F.
  full_name: Leclercq, F.
  last_name: Leclercq
- first_name: V.
  full_name: Abril-Melgarejo, V.
  last_name: Abril-Melgarejo
- first_name: L.
  full_name: Boogaard, L.
  last_name: Boogaard
- first_name: N. F.
  full_name: Bouché, N. F.
  last_name: Bouché
- first_name: T.
  full_name: Contini, T.
  last_name: Contini
- first_name: A.
  full_name: Feltre, A.
  last_name: Feltre
- first_name: B.
  full_name: Guiderdoni, B.
  last_name: Guiderdoni
- first_name: C.
  full_name: Herenz, C.
  last_name: Herenz
- first_name: W.
  full_name: Kollatschny, W.
  last_name: Kollatschny
- first_name: H.
  full_name: Kusakabe, H.
  last_name: Kusakabe
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: L.
  full_name: Michel-Dansac, L.
  last_name: Michel-Dansac
- first_name: T.
  full_name: Nanayakkara, T.
  last_name: Nanayakkara
- first_name: J.
  full_name: Richard, J.
  last_name: Richard
- first_name: M.
  full_name: Roth, M.
  last_name: Roth
- first_name: K. B.
  full_name: Schmidt, K. B.
  last_name: Schmidt
- first_name: M.
  full_name: Steinmetz, M.
  last_name: Steinmetz
- first_name: L.
  full_name: Tresse, L.
  last_name: Tresse
- first_name: T.
  full_name: Urrutia, T.
  last_name: Urrutia
- first_name: A.
  full_name: Verhamme, A.
  last_name: Verhamme
- first_name: P. M.
  full_name: Weilbacher, P. M.
  last_name: Weilbacher
- first_name: J.
  full_name: Zabl, J.
  last_name: Zabl
- first_name: S. L.
  full_name: Zoutendijk, S. L.
  last_name: Zoutendijk
citation:
  ama: 'Bacon R, Mary D, Garel T, et al. The MUSE Extremely Deep Field: The cosmic
    web in emission at high redshift. <i>Astronomy &#38; Astrophysics</i>. 2021;647.
    doi:<a href="https://doi.org/10.1051/0004-6361/202039887">10.1051/0004-6361/202039887</a>'
  apa: 'Bacon, R., Mary, D., Garel, T., Blaizot, J., Maseda, M., Schaye, J., … Zoutendijk,
    S. L. (2021). The MUSE Extremely Deep Field: The cosmic web in emission at high
    redshift. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202039887">https://doi.org/10.1051/0004-6361/202039887</a>'
  chicago: 'Bacon, R., D. Mary, T. Garel, J. Blaizot, M. Maseda, J. Schaye, L. Wisotzki,
    et al. “The MUSE Extremely Deep Field: The Cosmic Web in Emission at High Redshift.”
    <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2021. <a href="https://doi.org/10.1051/0004-6361/202039887">https://doi.org/10.1051/0004-6361/202039887</a>.'
  ieee: 'R. Bacon <i>et al.</i>, “The MUSE Extremely Deep Field: The cosmic web in
    emission at high redshift,” <i>Astronomy &#38; Astrophysics</i>, vol. 647. EDP
    Sciences, 2021.'
  ista: 'Bacon R, Mary D, Garel T, Blaizot J, Maseda M, Schaye J, Wisotzki L, Conseil
    S, Brinchmann J, Leclercq F, Abril-Melgarejo V, Boogaard L, Bouché NF, Contini
    T, Feltre A, Guiderdoni B, Herenz C, Kollatschny W, Kusakabe H, Matthee JJ, Michel-Dansac
    L, Nanayakkara T, Richard J, Roth M, Schmidt KB, Steinmetz M, Tresse L, Urrutia
    T, Verhamme A, Weilbacher PM, Zabl J, Zoutendijk SL. 2021. The MUSE Extremely
    Deep Field: The cosmic web in emission at high redshift. Astronomy &#38; Astrophysics.
    647, A107.'
  mla: 'Bacon, R., et al. “The MUSE Extremely Deep Field: The Cosmic Web in Emission
    at High Redshift.” <i>Astronomy &#38; Astrophysics</i>, vol. 647, A107, EDP Sciences,
    2021, doi:<a href="https://doi.org/10.1051/0004-6361/202039887">10.1051/0004-6361/202039887</a>.'
  short: R. Bacon, D. Mary, T. Garel, J. Blaizot, M. Maseda, J. Schaye, L. Wisotzki,
    S. Conseil, J. Brinchmann, F. Leclercq, V. Abril-Melgarejo, L. Boogaard, N.F.
    Bouché, T. Contini, A. Feltre, B. Guiderdoni, C. Herenz, W. Kollatschny, H. Kusakabe,
    J.J. Matthee, L. Michel-Dansac, T. Nanayakkara, J. Richard, M. Roth, K.B. Schmidt,
    M. Steinmetz, L. Tresse, T. Urrutia, A. Verhamme, P.M. Weilbacher, J. Zabl, S.L.
    Zoutendijk, Astronomy &#38; Astrophysics 647 (2021).
date_created: 2022-07-06T09:31:50Z
date_published: 2021-03-18T00:00:00Z
date_updated: 2022-07-19T09:34:57Z
day: '18'
doi: 10.1051/0004-6361/202039887
extern: '1'
external_id:
  arxiv:
  - '2102.05516'
intvolume: '       647'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- 'galaxies: high-redshift / galaxies: groups: general / cosmology: observations'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2102.05516
month: '03'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The MUSE Extremely Deep Field: The cosmic web in emission at high redshift'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 647
year: '2021'
...
---
_id: '11522'
abstract:
- lang: eng
  text: The decline in abundance of Lyman-α (Lyα) emitting galaxies at z ≳ 6 is a
    powerful and commonly used probe to constrain the progress of cosmic reionization.
    We use the CODAII simulation, which is a radiation hydrodynamic simulation featuring
    a box of ∼94 comoving Mpc side length, to compute the Lyα transmission properties
    of the intergalactic medium (IGM) at z ∼ 5.8 to 7. Our results mainly confirm
    previous studies, i.e. we find a declining Lyα transmission with redshift and
    a large sightline-to-sightline variation. However, motivated by the recent discovery
    of blue Lyα peaks at high redshift, we also analyse the IGM transmission on the
    blue side, which shows a rapid decline at z ≳ 6 of the blue transmission. This
    low transmission can be attributed not only to the presence of neutral regions
    but also to the residual neutral hydrogen within ionized regions, for which a
    density even as low as nHI∼10−9cm−3 (sometimes combined with kinematic effects)
    leads to a significantly reduced visibility. Still, we find that ∼1 per cent of
    sightlines towards M1600AB ∼ −21 galaxies at z ∼ 7 are transparent enough to allow
    a transmission of a blue Lyα peak. We discuss our results in the context of the
    interpretation of observations.
acknowledgement: The authors thank the referee for constructive feedback that improved
  the outcome of this study. We are grateful to Antoinette Songaila Cowie for sharing
  the ‘NEPLA4’ spectrum with us. This research has made use of NASA’s Astrophysics
  Data System, and many open source projects such as trident (Hummels et al. 2017),
  IPython (Pérez & Granger 2007), SciPy (Virtanen et al. 2019), NumPy (Walt et al.
  2011), matplotlib (Hunter 2007), pandas (McKinney 2010), and the yt-project (Turk
  et al. 2011). MG was supported by NASA through the NASA Hubble Fellowship grant
  HST-HF2-51409 awarded by the Space Telescope Science Institute, which is operated
  by the Association of Universities for Research in Astronomy, Inc., for NASA, under
  contract NAS5-26555. MG acknowledges support from NASA grants HST-GO-15643.017,
  and HST-AR15797.001 as well as XSEDE grant TG-AST180036. CAM acknowledges support
  by NASA Headquarters through the NASA Hubble Fellowship grant HST-HF2-51413.001-A.
  PRS was supported in part by U.S. NSF grant AST-1009799, NASA grant NNX11AE09G,
  and supercomputer resources from NSF XSEDE grant TG AST090005 and the Texas Advanced
  Computing Center (TACC) at The University of Texas at Austin. JM acknowledges a
  Zwicky Prize Fellowship from ETH Zurich. GY acknowledges financial support by MICIU/FEDER
  under project grant PGC2018-094975-C21. SEIB acknowledges funding from the European
  Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
  programme (grant agreement No. 669253). ITI was supported by the Science and Technology
  Facilities Council [grants ST/I000976/1, ST/F002858/1, ST/P000525/1, and ST/T000473/1];
  and The Southeast Physics Network (SEPNet). KA was supported by NRF2016R1D1A1B04935414
  and NRF-2016R1A5A1013277. KA also appreciates APCTP for its hospitality during completion
  of this work. PO acknowledges support from the French ANR funded project ORAGE (ANR-14-CE33-0016).
  ND and DA acknowledge funding from the French ANR for project ANR-12-JS05- 0001
  (EMMA). The CoDa II simulation was performed at Oak Ridge National Laboratory/Oak
  Ridge Leadership Computing Facility on the Titan supercomputer (INCITE 2016 award
  AST031). Processing was performed on the Eos and Rhea clusters. Resolution study
  simulations were performed on Piz Daint at the Swiss National Supercomputing Center
  (PRACE Tier 0 award, project id pr37). The authors would like to acknowledge the
  High Performance Computing center of the University of Strasbourg for supporting
  this work by providing scientific support and access to computing resources. Part
  of the computing resources were funded by the Equipex EquipMeso project (Programme
  Investissements d’Avenir) and the CPER Alsacalcul/Big Data.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Max
  full_name: Gronke, Max
  last_name: Gronke
- first_name: Pierre
  full_name: Ocvirk, Pierre
  last_name: Ocvirk
- first_name: Charlotte
  full_name: Mason, Charlotte
  last_name: Mason
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Sarah E I
  full_name: Bosman, Sarah E I
  last_name: Bosman
- first_name: Jenny G
  full_name: Sorce, Jenny G
  last_name: Sorce
- first_name: Joseph
  full_name: Lewis, Joseph
  last_name: Lewis
- first_name: Kyungjin
  full_name: Ahn, Kyungjin
  last_name: Ahn
- first_name: Dominique
  full_name: Aubert, Dominique
  last_name: Aubert
- first_name: Taha
  full_name: Dawoodbhoy, Taha
  last_name: Dawoodbhoy
- first_name: Ilian T
  full_name: Iliev, Ilian T
  last_name: Iliev
- first_name: Paul R
  full_name: Shapiro, Paul R
  last_name: Shapiro
- first_name: Gustavo
  full_name: Yepes, Gustavo
  last_name: Yepes
citation:
  ama: Gronke M, Ocvirk P, Mason C, et al. Lyman-α transmission properties of the
    intergalactic medium in the CoDaII simulation. <i>Monthly Notices of the Royal
    Astronomical Society</i>. 2021;508(3):3697-3709. doi:<a href="https://doi.org/10.1093/mnras/stab2762">10.1093/mnras/stab2762</a>
  apa: Gronke, M., Ocvirk, P., Mason, C., Matthee, J. J., Bosman, S. E. I., Sorce,
    J. G., … Yepes, G. (2021). Lyman-α transmission properties of the intergalactic
    medium in the CoDaII simulation. <i>Monthly Notices of the Royal Astronomical
    Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/stab2762">https://doi.org/10.1093/mnras/stab2762</a>
  chicago: Gronke, Max, Pierre Ocvirk, Charlotte Mason, Jorryt J Matthee, Sarah E
    I Bosman, Jenny G Sorce, Joseph Lewis, et al. “Lyman-α Transmission Properties
    of the Intergalactic Medium in the CoDaII Simulation.” <i>Monthly Notices of the
    Royal Astronomical Society</i>. Oxford University Press, 2021. <a href="https://doi.org/10.1093/mnras/stab2762">https://doi.org/10.1093/mnras/stab2762</a>.
  ieee: M. Gronke <i>et al.</i>, “Lyman-α transmission properties of the intergalactic
    medium in the CoDaII simulation,” <i>Monthly Notices of the Royal Astronomical
    Society</i>, vol. 508, no. 3. Oxford University Press, pp. 3697–3709, 2021.
  ista: Gronke M, Ocvirk P, Mason C, Matthee JJ, Bosman SEI, Sorce JG, Lewis J, Ahn
    K, Aubert D, Dawoodbhoy T, Iliev IT, Shapiro PR, Yepes G. 2021. Lyman-α transmission
    properties of the intergalactic medium in the CoDaII simulation. Monthly Notices
    of the Royal Astronomical Society. 508(3), 3697–3709.
  mla: Gronke, Max, et al. “Lyman-α Transmission Properties of the Intergalactic Medium
    in the CoDaII Simulation.” <i>Monthly Notices of the Royal Astronomical Society</i>,
    vol. 508, no. 3, Oxford University Press, 2021, pp. 3697–709, doi:<a href="https://doi.org/10.1093/mnras/stab2762">10.1093/mnras/stab2762</a>.
  short: M. Gronke, P. Ocvirk, C. Mason, J.J. Matthee, S.E.I. Bosman, J.G. Sorce,
    J. Lewis, K. Ahn, D. Aubert, T. Dawoodbhoy, I.T. Iliev, P.R. Shapiro, G. Yepes,
    Monthly Notices of the Royal Astronomical Society 508 (2021) 3697–3709.
date_created: 2022-07-07T09:30:21Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2022-08-18T10:45:56Z
day: '01'
doi: 10.1093/mnras/stab2762
extern: '1'
external_id:
  arxiv:
  - '2004.14496'
intvolume: '       508'
issue: '3'
keyword:
- dark ages
- reionization
- first stars
- intergalactic medium
- 'galaxies: formation'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2004.14496
month: '12'
oa: 1
oa_version: Preprint
page: 3697-3709
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Lyman-α transmission properties of the intergalactic medium in the CoDaII simulation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 508
year: '2021'
...
---
_id: '11524'
abstract:
- lang: eng
  text: We measure the evolution of the rest-frame UV luminosity function (LF) and
    the stellar mass function (SMF) of Lyman-α (Ly α) emitters (LAEs) from z ∼ 2 to
    z ∼ 6 by exploring ∼4000 LAEs from the SC4K sample. We find a correlation between
    Ly α luminosity (LLy α) and rest-frame UV (MUV), with best fit MUV=−1.6+0.2−0.3log10(LLyα/ergs−1)+47+12−11
    and a shallower relation between LLy α and stellar mass (M⋆), with best fit log10(M⋆/M⊙)=0.9+0.1−0.1log10(LLyα/ergs−1)−28+4.0−3.8⁠.
    An increasing LLy α cut predominantly lowers the number density of faint MUV and
    low M⋆ LAEs. We estimate a proxy for the full UV LFs and SMFs of LAEs with simple
    assumptions of the faint end slope. For the UV LF, we find a brightening of the
    characteristic UV luminosity (M∗UV⁠) with increasing redshift and a decrease of
    the characteristic number density (Φ*). For the SMF, we measure a characteristic
    stellar mass (⁠M∗⋆/M⊙⁠) increase with increasing redshift, and a Φ* decline. However,
    if we apply a uniform luminosity cut of log10(LLyα/ergs−1)≥43.0⁠, we find much
    milder to no evolution in the UV and SMF of LAEs. The UV luminosity density (ρUV)
    of the full sample of LAEs shows moderate evolution and the stellar mass density
    (ρM) decreases, with both being always lower than the total ρUV and ρM of more
    typical galaxies but slowly approaching them with increasing redshift. Overall,
    our results indicate that both ρUV and ρM of LAEs slowly approach the measurements
    of continuum-selected galaxies at z > 6, which suggests a key role of LAEs in
    the epoch of reionization.
acknowledgement: This research made use of Astropy, a community developed core Python
  package for Astronomy (Astropy Collaboration et al. 2013). topcat, a graphical tool
  for manipulating tabular data, was also utilized in this analysis (Taylor 2005).
  SG would like to thank Nastasha Wijers for the discussion on the column density
  distribution in EAGLE. SC gratefully acknowledges support from Swiss National Science
  Foundation grants PP00P2 163824 and PP00P2 190092, and from the European Research
  Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
  grant agreement No 864361. GP acknowledges support from the Swiss National Science
  Foundation (SNF) and from the Netherlands Research School for Astronomy (NOVA).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: S
  full_name: Santos, S
  last_name: Santos
- first_name: D
  full_name: Sobral, D
  last_name: Sobral
- first_name: J
  full_name: Butterworth, J
  last_name: Butterworth
- first_name: A
  full_name: Paulino-Afonso, A
  last_name: Paulino-Afonso
- first_name: B
  full_name: Ribeiro, B
  last_name: Ribeiro
- first_name: E
  full_name: da Cunha, E
  last_name: da Cunha
- first_name: J
  full_name: Calhau, J
  last_name: Calhau
- first_name: A A
  full_name: Khostovan, A A
  last_name: Khostovan
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: P
  full_name: Arrabal Haro, P
  last_name: Arrabal Haro
citation:
  ama: Santos S, Sobral D, Butterworth J, et al. The evolution of the UV luminosity
    and stellar mass functions of Lyman-α emitters from z ∼ 2 to z ∼ 6. <i>Monthly
    Notices of the Royal Astronomical Society</i>. 2021;505(1):1117-1134. doi:<a href="https://doi.org/10.1093/mnras/stab1218">10.1093/mnras/stab1218</a>
  apa: Santos, S., Sobral, D., Butterworth, J., Paulino-Afonso, A., Ribeiro, B., da Cunha,
    E., … Arrabal Haro, P. (2021). The evolution of the UV luminosity and stellar
    mass functions of Lyman-α emitters from z ∼ 2 to z ∼ 6. <i>Monthly Notices of
    the Royal Astronomical Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/stab1218">https://doi.org/10.1093/mnras/stab1218</a>
  chicago: Santos, S, D Sobral, J Butterworth, A Paulino-Afonso, B Ribeiro, E da Cunha,
    J Calhau, A A Khostovan, Jorryt J Matthee, and P Arrabal Haro. “The Evolution
    of the UV Luminosity and Stellar Mass Functions of Lyman-α Emitters from z ∼ 2
    to z ∼ 6.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University
    Press, 2021. <a href="https://doi.org/10.1093/mnras/stab1218">https://doi.org/10.1093/mnras/stab1218</a>.
  ieee: S. Santos <i>et al.</i>, “The evolution of the UV luminosity and stellar mass
    functions of Lyman-α emitters from z ∼ 2 to z ∼ 6,” <i>Monthly Notices of the
    Royal Astronomical Society</i>, vol. 505, no. 1. Oxford University Press, pp.
    1117–1134, 2021.
  ista: Santos S, Sobral D, Butterworth J, Paulino-Afonso A, Ribeiro B, da Cunha E,
    Calhau J, Khostovan AA, Matthee JJ, Arrabal Haro P. 2021. The evolution of the
    UV luminosity and stellar mass functions of Lyman-α emitters from z ∼ 2 to z ∼
    6. Monthly Notices of the Royal Astronomical Society. 505(1), 1117–1134.
  mla: Santos, S., et al. “The Evolution of the UV Luminosity and Stellar Mass Functions
    of Lyman-α Emitters from z ∼ 2 to z ∼ 6.” <i>Monthly Notices of the Royal Astronomical
    Society</i>, vol. 505, no. 1, Oxford University Press, 2021, pp. 1117–34, doi:<a
    href="https://doi.org/10.1093/mnras/stab1218">10.1093/mnras/stab1218</a>.
  short: S. Santos, D. Sobral, J. Butterworth, A. Paulino-Afonso, B. Ribeiro, E. da Cunha,
    J. Calhau, A.A. Khostovan, J.J. Matthee, P. Arrabal Haro, Monthly Notices of the
    Royal Astronomical Society 505 (2021) 1117–1134.
date_created: 2022-07-07T10:02:59Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2022-08-18T10:51:47Z
day: '01'
doi: 10.1093/mnras/stab1218
extern: '1'
external_id:
  arxiv:
  - '2105.00007'
intvolume: '       505'
issue: '1'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- 'galaxies: evolution'
- 'galaxies: high-redshift'
- 'galaxies: luminosity function'
- mass function
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2105.00007
month: '07'
oa: 1
oa_version: Preprint
page: 1117-1134
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The evolution of the UV luminosity and stellar mass functions of Lyman-α emitters
  from z ∼ 2 to z ∼ 6
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 505
year: '2021'
...
---
_id: '11756'
abstract:
- lang: eng
  text: We give two fully dynamic algorithms that maintain a (1 + ε)-approximation
    of the weight M of a minimum spanning forest (MSF) of an n-node graph G with edges
    weights in [1, W ], for any ε > 0. (1) Our deterministic algorithm takes O (W
    2 log W /ε3) worst-case update time, which is O (1) if both W and ε are constants.
    (2) Our randomized (Monte-Carlo style) algorithm works with high probability and
    runs in worst-case O (log W /ε4) update time if W = O ((m∗)1/6/log2/3 n), where
    m∗ is the minimum number of edges in the graph throughout all the updates. It
    works even against an adaptive adversary. We complement our algorithmic results
    with two cell-probe lower bounds for dynamically maintaining an approximation
    of the weight of an MSF of a graph.
article_number: '104805'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Pan
  full_name: Peng, Pan
  last_name: Peng
citation:
  ama: Henzinger M, Peng P. Constant-time dynamic weight approximation for minimum
    spanning forest. <i>Information and Computation</i>. 2021;281(12). doi:<a href="https://doi.org/10.1016/j.ic.2021.104805">10.1016/j.ic.2021.104805</a>
  apa: Henzinger, M., &#38; Peng, P. (2021). Constant-time dynamic weight approximation
    for minimum spanning forest. <i>Information and Computation</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.ic.2021.104805">https://doi.org/10.1016/j.ic.2021.104805</a>
  chicago: Henzinger, Monika, and Pan Peng. “Constant-Time Dynamic Weight Approximation
    for Minimum Spanning Forest.” <i>Information and Computation</i>. Elsevier, 2021.
    <a href="https://doi.org/10.1016/j.ic.2021.104805">https://doi.org/10.1016/j.ic.2021.104805</a>.
  ieee: M. Henzinger and P. Peng, “Constant-time dynamic weight approximation for
    minimum spanning forest,” <i>Information and Computation</i>, vol. 281, no. 12.
    Elsevier, 2021.
  ista: Henzinger M, Peng P. 2021. Constant-time dynamic weight approximation for
    minimum spanning forest. Information and Computation. 281(12), 104805.
  mla: Henzinger, Monika, and Pan Peng. “Constant-Time Dynamic Weight Approximation
    for Minimum Spanning Forest.” <i>Information and Computation</i>, vol. 281, no.
    12, 104805, Elsevier, 2021, doi:<a href="https://doi.org/10.1016/j.ic.2021.104805">10.1016/j.ic.2021.104805</a>.
  short: M. Henzinger, P. Peng, Information and Computation 281 (2021).
date_created: 2022-08-08T10:58:29Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2024-11-06T12:09:22Z
day: '01'
doi: 10.1016/j.ic.2021.104805
extern: '1'
external_id:
  arxiv:
  - '2011.00977'
intvolume: '       281'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2011.00977
month: '12'
oa: 1
oa_version: Preprint
publication: Information and Computation
publication_identifier:
  issn:
  - 0890-5401
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Constant-time dynamic weight approximation for minimum spanning forest
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 281
year: '2021'
...
---
_id: '11886'
abstract:
- lang: eng
  text: "We present a deterministic (1+\U0001D45C(1))-approximation (\U0001D45B1/2+\U0001D45C(1)+\U0001D4371+\U0001D45C(1))-time
    algorithm for solving the single-source shortest paths problem on distributed
    weighted networks (the \\sf CONGEST model); here \U0001D45B is the number of nodes
    in the network, \U0001D437 is its (hop) diameter, and edge weights are positive
    integers from 1 to poly(\U0001D45B). This is the first nontrivial deterministic
    algorithm for this problem. It also improves (i) the running time of the randomized
    (1+\U0001D45C(1))-approximation \U0001D442̃ (\U0001D45B√\U0001D4371/4+\U0001D437)-time
    algorithm of Nanongkai [in Proceedings of STOC, 2014, pp. 565--573] by a factor
    of as large as \U0001D45B1/8, and (ii) the \U0001D442(\U0001D716−1log\U0001D716−1)-approximation
    factor of Lenzen and Patt-Shamir's \U0001D442̃ (\U0001D45B1/2+\U0001D716+\U0001D437)-time
    algorithm [in Proceedings of STOC, 2013, pp. 381--390] within the same running
    time. (Throughout, we use \U0001D442̃ (⋅) to hide polylogarithmic factors in \U0001D45B.)
    Our running time matches the known time lower bound of Ω(\U0001D45B/log\U0001D45B‾‾‾‾‾‾‾√+\U0001D437)
    [M. Elkin, SIAM J. Comput., 36 (2006), pp. 433--456], thus essentially settling
    the status of this problem which was raised at least a decade ago [M. Elkin, SIGACT
    News, 35 (2004), pp. 40--57]. It also implies a (2+\U0001D45C(1))-approximation
    (\U0001D45B1/2+\U0001D45C(1)+\U0001D4371+\U0001D45C(1))-time algorithm for approximating
    a network's weighted diameter which almost matches the lower bound by Holzer and
    Pinsker [in Proceedings of OPODIS, 2015, Schloss Dagstuhl. Leibniz-Zent. Inform.,
    Wadern, Germany, 2016, 6]. In achieving this result, we develop two techniques
    which might be of independent interest and useful in other settings: (i) a deterministic
    process that replaces the “hitting set argument” commonly used for shortest paths
    computation in various settings, and (ii) a simple, deterministic construction
    of an (\U0001D45B\U0001D45C(1),\U0001D45C(1))-hop set of size \U0001D45B1+\U0001D45C(1).
    We combine these techniques with many distributed algorithmic techniques, some
    of which are from problems that are not directly related to shortest paths, e.g.,
    ruling sets [A. V. Goldberg, S. A. Plotkin, and G. E. Shannon, SIAM J. Discrete
    Math., 1 (1988), pp. 434--446], source detection [C. Lenzen and D. Peleg, in Proceedings
    of PODC, 2013, pp. 375--382], and partial distance estimation [C. Lenzen and B.
    Patt-Shamir, in Proceedings of PODC, 2015, pp. 153--162]. Our hop set construction
    also leads to single-source shortest paths algorithms in two other settings: (i)
    a (1+\U0001D45C(1))-approximation \U0001D45B\U0001D45C(1)-time algorithm on congested
    cliques, and (ii) a (1+\U0001D45C(1))-approximation \U0001D45B\U0001D45C(1)-pass
    \U0001D45B1+\U0001D45C(1)-space streaming algorithm. The first result answers
    an open problem in [D. Nanongkai, in Proceedings of STOC, 2014, pp. 565--573].
    The second result partially answers an open problem raised by McGregor in 2006
    [List of Open Problems in Sublinear Algorithms: Problem 14]."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Sebastian
  full_name: Krinninger, Sebastian
  last_name: Krinninger
- first_name: Danupon
  full_name: Nanongkai, Danupon
  last_name: Nanongkai
citation:
  ama: Henzinger M, Krinninger S, Nanongkai D. A deterministic almost-tight distributed
    algorithm for approximating single-source shortest paths. <i>SIAM Journal on Computing</i>.
    2021;50(3):STOC16-98-STOC16-137. doi:<a href="https://doi.org/10.1137/16m1097808">10.1137/16m1097808</a>
  apa: Henzinger, M., Krinninger, S., &#38; Nanongkai, D. (2021). A deterministic
    almost-tight distributed algorithm for approximating single-source shortest paths.
    <i>SIAM Journal on Computing</i>. Society for Industrial &#38; Applied Mathematics.
    <a href="https://doi.org/10.1137/16m1097808">https://doi.org/10.1137/16m1097808</a>
  chicago: Henzinger, Monika, Sebastian Krinninger, and Danupon Nanongkai. “A Deterministic
    Almost-Tight Distributed Algorithm for Approximating Single-Source Shortest Paths.”
    <i>SIAM Journal on Computing</i>. Society for Industrial &#38; Applied Mathematics,
    2021. <a href="https://doi.org/10.1137/16m1097808">https://doi.org/10.1137/16m1097808</a>.
  ieee: M. Henzinger, S. Krinninger, and D. Nanongkai, “A deterministic almost-tight
    distributed algorithm for approximating single-source shortest paths,” <i>SIAM
    Journal on Computing</i>, vol. 50, no. 3. Society for Industrial &#38; Applied
    Mathematics, pp. STOC16-98-STOC16-137, 2021.
  ista: Henzinger M, Krinninger S, Nanongkai D. 2021. A deterministic almost-tight
    distributed algorithm for approximating single-source shortest paths. SIAM Journal
    on Computing. 50(3), STOC16-98-STOC16-137.
  mla: Henzinger, Monika, et al. “A Deterministic Almost-Tight Distributed Algorithm
    for Approximating Single-Source Shortest Paths.” <i>SIAM Journal on Computing</i>,
    vol. 50, no. 3, Society for Industrial &#38; Applied Mathematics, 2021, pp. STOC16-98-STOC16-137,
    doi:<a href="https://doi.org/10.1137/16m1097808">10.1137/16m1097808</a>.
  short: M. Henzinger, S. Krinninger, D. Nanongkai, SIAM Journal on Computing 50 (2021)
    STOC16-98-STOC16-137.
date_created: 2022-08-17T07:54:45Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2024-11-06T12:22:31Z
day: '01'
doi: 10.1137/16m1097808
extern: '1'
external_id:
  arxiv:
  - '1504.07056'
intvolume: '        50'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1504.07056
month: '05'
oa: 1
oa_version: Preprint
page: STOC16-98-STOC16-137
publication: SIAM Journal on Computing
publication_identifier:
  eissn:
  - 1095-7111
  issn:
  - 0097-5397
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: A deterministic almost-tight distributed algorithm for approximating single-source
  shortest paths
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2021'
...
---
_id: '13072'
abstract:
- lang: eng
  text: CpGs and corresponding mean weights for DNAm-based prediction of cognitive
    abilities (6 traits)
article_processing_charge: No
author:
- first_name: Daniel L
  full_name: McCartney, Daniel L
  last_name: McCartney
- first_name: Robert F
  full_name: Hillary, Robert F
  last_name: Hillary
- first_name: Eleanor LS
  full_name: Conole, Eleanor LS
  last_name: Conole
- first_name: Daniel
  full_name: Trejo Banos, Daniel
  last_name: Trejo Banos
- first_name: Danni A
  full_name: Gadd, Danni A
  last_name: Gadd
- first_name: Rosie M
  full_name: Walker, Rosie M
  last_name: Walker
- first_name: Cliff
  full_name: Nangle, Cliff
  last_name: Nangle
- first_name: Robin
  full_name: Flaig, Robin
  last_name: Flaig
- first_name: Archie
  full_name: Campbell, Archie
  last_name: Campbell
- first_name: Alison D
  full_name: Murray, Alison D
  last_name: Murray
- first_name: Susana
  full_name: Munoz Maniega, Susana
  last_name: Munoz Maniega
- first_name: Maria
  full_name: del C Valdes-Hernandez, Maria
  last_name: del C Valdes-Hernandez
- first_name: Mathew A
  full_name: Harris, Mathew A
  last_name: Harris
- first_name: Mark E
  full_name: Bastin, Mark E
  last_name: Bastin
- first_name: Joanna M
  full_name: Wardlaw, Joanna M
  last_name: Wardlaw
- first_name: Sarah E
  full_name: Harris, Sarah E
  last_name: Harris
- first_name: David J
  full_name: Porteous, David J
  last_name: Porteous
- first_name: Elliot M
  full_name: Tucker-Drob, Elliot M
  last_name: Tucker-Drob
- first_name: Andrew M
  full_name: McIntosh, Andrew M
  last_name: McIntosh
- first_name: Kathryn L
  full_name: Evans, Kathryn L
  last_name: Evans
- first_name: Ian J
  full_name: Deary, Ian J
  last_name: Deary
- first_name: Simon R
  full_name: Cox, Simon R
  last_name: Cox
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
- first_name: Riccardo E
  full_name: Marioni, Riccardo E
  last_name: Marioni
citation:
  ama: McCartney DL, Hillary RF, Conole EL, et al. Blood-based epigenome-wide analyses
    of cognitive abilities. 2021. doi:<a href="https://doi.org/10.5281/ZENODO.5794028">10.5281/ZENODO.5794028</a>
  apa: McCartney, D. L., Hillary, R. F., Conole, E. L., Trejo Banos, D., Gadd, D.
    A., Walker, R. M., … Marioni, R. E. (2021). Blood-based epigenome-wide analyses
    of cognitive abilities. Zenodo. <a href="https://doi.org/10.5281/ZENODO.5794028">https://doi.org/10.5281/ZENODO.5794028</a>
  chicago: McCartney, Daniel L, Robert F Hillary, Eleanor LS Conole, Daniel Trejo
    Banos, Danni A Gadd, Rosie M Walker, Cliff Nangle, et al. “Blood-Based Epigenome-Wide
    Analyses of Cognitive Abilities.” Zenodo, 2021. <a href="https://doi.org/10.5281/ZENODO.5794028">https://doi.org/10.5281/ZENODO.5794028</a>.
  ieee: D. L. McCartney <i>et al.</i>, “Blood-based epigenome-wide analyses of cognitive
    abilities.” Zenodo, 2021.
  ista: McCartney DL, Hillary RF, Conole EL, Trejo Banos D, Gadd DA, Walker RM, Nangle
    C, Flaig R, Campbell A, Murray AD, Munoz Maniega S, del C Valdes-Hernandez M,
    Harris MA, Bastin ME, Wardlaw JM, Harris SE, Porteous DJ, Tucker-Drob EM, McIntosh
    AM, Evans KL, Deary IJ, Cox SR, Robinson MR, Marioni RE. 2021. Blood-based epigenome-wide
    analyses of cognitive abilities, Zenodo, <a href="https://doi.org/10.5281/ZENODO.5794028">10.5281/ZENODO.5794028</a>.
  mla: McCartney, Daniel L., et al. <i>Blood-Based Epigenome-Wide Analyses of Cognitive
    Abilities</i>. Zenodo, 2021, doi:<a href="https://doi.org/10.5281/ZENODO.5794028">10.5281/ZENODO.5794028</a>.
  short: D.L. McCartney, R.F. Hillary, E.L. Conole, D. Trejo Banos, D.A. Gadd, R.M.
    Walker, C. Nangle, R. Flaig, A. Campbell, A.D. Murray, S. Munoz Maniega, M. del
    C Valdes-Hernandez, M.A. Harris, M.E. Bastin, J.M. Wardlaw, S.E. Harris, D.J.
    Porteous, E.M. Tucker-Drob, A.M. McIntosh, K.L. Evans, I.J. Deary, S.R. Cox, M.R.
    Robinson, R.E. Marioni, (2021).
date_created: 2023-05-23T16:46:20Z
date_published: 2021-12-20T00:00:00Z
date_updated: 2025-06-11T13:54:53Z
day: '20'
ddc:
- '570'
department:
- _id: MaRo
doi: 10.5281/ZENODO.5794028
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/zenodo.5794029
month: '12'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '10702'
    relation: used_in_publication
    status: public
status: public
title: Blood-based epigenome-wide analyses of cognitive abilities
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '15219'
abstract:
- lang: eng
  text: We have carried out a search for massive white dwarfs (WDs) in the direction
    of young open star clusters using the Gaia DR2 database. The aim of this survey
    was (1) to provide robust data for new and previously known high-mass WDs regarding
    cluster membership, (2) to highlight WDs previously included in the initial final
    mass relation (IFMR) that are unlikely members of their respective clusters according
    to Gaia astrometry, and (3) to select an unequivocal WD sample that could then
    be compared with the host clusters' turnoff masses. All promising WD candidates
    in each cluster color–magnitude diagram were followed up with spectroscopy from
    Gemini in order to determine whether they were indeed WDs and derive their masses,
    temperatures, and ages. In order to be considered cluster members, white dwarfs
    were required to (1) have proper motions and parallaxes within 2σ, 3σ, or 4σ of
    those of their potential parent cluster based on how contaminated the field was
    in their region of the sky, (2) have a cooling age that was less than the cluster
    age, and (3) have a mass that was broadly consistent with the IFMR. A number of
    WDs included in current versions of the IFMR turned out to be nonmembers, and
    a number of apparent members, based on Gaia's astrometric data alone, were rejected,
    as their mass and/or cooling times were incompatible with cluster membership.
    In this way, we developed a highly selected IFMR sample for high-mass WDs that,
    surprisingly, contained no precursor masses significantly in excess of ∼ 6 M⊙.
article_number: '165'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Harvey B.
  full_name: Richer, Harvey B.
  last_name: Richer
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: Helen
  full_name: Du, Helen
  last_name: Du
- first_name: Steffani
  full_name: Grondin, Steffani
  last_name: Grondin
- first_name: James
  full_name: Hegarty, James
  last_name: Hegarty
- first_name: Jeremy
  full_name: Heyl, Jeremy
  last_name: Heyl
- first_name: Ronan
  full_name: Kerr, Ronan
  last_name: Kerr
- first_name: David R.
  full_name: Miller, David R.
  last_name: Miller
- first_name: Sarah
  full_name: Thiele, Sarah
  last_name: Thiele
citation:
  ama: Richer HB, Caiazzo I, Du H, et al. Massive white dwarfs in young star clusters.
    <i>The Astrophysical Journal</i>. 2021;912(2). doi:<a href="https://doi.org/10.3847/1538-4357/abdeb7">10.3847/1538-4357/abdeb7</a>
  apa: Richer, H. B., Caiazzo, I., Du, H., Grondin, S., Hegarty, J., Heyl, J., … Thiele,
    S. (2021). Massive white dwarfs in young star clusters. <i>The Astrophysical Journal</i>.
    American Astronomical Society. <a href="https://doi.org/10.3847/1538-4357/abdeb7">https://doi.org/10.3847/1538-4357/abdeb7</a>
  chicago: Richer, Harvey B., Ilaria Caiazzo, Helen Du, Steffani Grondin, James Hegarty,
    Jeremy Heyl, Ronan Kerr, David R. Miller, and Sarah Thiele. “Massive White Dwarfs
    in Young Star Clusters.” <i>The Astrophysical Journal</i>. American Astronomical
    Society, 2021. <a href="https://doi.org/10.3847/1538-4357/abdeb7">https://doi.org/10.3847/1538-4357/abdeb7</a>.
  ieee: H. B. Richer <i>et al.</i>, “Massive white dwarfs in young star clusters,”
    <i>The Astrophysical Journal</i>, vol. 912, no. 2. American Astronomical Society,
    2021.
  ista: Richer HB, Caiazzo I, Du H, Grondin S, Hegarty J, Heyl J, Kerr R, Miller DR,
    Thiele S. 2021. Massive white dwarfs in young star clusters. The Astrophysical
    Journal. 912(2), 165.
  mla: Richer, Harvey B., et al. “Massive White Dwarfs in Young Star Clusters.” <i>The
    Astrophysical Journal</i>, vol. 912, no. 2, 165, American Astronomical Society,
    2021, doi:<a href="https://doi.org/10.3847/1538-4357/abdeb7">10.3847/1538-4357/abdeb7</a>.
  short: H.B. Richer, I. Caiazzo, H. Du, S. Grondin, J. Hegarty, J. Heyl, R. Kerr,
    D.R. Miller, S. Thiele, The Astrophysical Journal 912 (2021).
date_created: 2024-03-26T10:33:23Z
date_published: 2021-05-17T00:00:00Z
date_updated: 2024-04-03T14:11:17Z
day: '17'
doi: 10.3847/1538-4357/abdeb7
extern: '1'
external_id:
  arxiv:
  - '2101.08300'
intvolume: '       912'
issue: '2'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2101.08300
month: '05'
oa: 1
oa_version: Preprint
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Massive white dwarfs in young star clusters
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 912
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '19492'
abstract:
- lang: eng
  text: Kuroda’s formula relates the class number of a multiquadratic number field
    K to the class numbers of its quadratic subfields ki. A key component in this
    formula is the unit group index (math formular). We study how Q(K) behaves on
    average in certain natural families of totally real biquadratic fields K parametrized
    by prime numbers.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Yik Tung
  full_name: Chan, Yik Tung
  id: c4c0afc8-9262-11ed-9231-d8b0bc743af1
  last_name: Chan
  orcid: 0000-0001-8467-4106
- first_name: Djordjo
  full_name: Milovic, Djordjo
  last_name: Milovic
citation:
  ama: Chan S, Milovic D. Kuroda’s formula and arithmetic statistics. <i>Mathematische
    Zeitschrift</i>. 2021;300(2):1509-1527. doi:<a href="https://doi.org/10.1007/s00209-021-02823-6">10.1007/s00209-021-02823-6</a>
  apa: Chan, S., &#38; Milovic, D. (2021). Kuroda’s formula and arithmetic statistics.
    <i>Mathematische Zeitschrift</i>. Springer Nature. <a href="https://doi.org/10.1007/s00209-021-02823-6">https://doi.org/10.1007/s00209-021-02823-6</a>
  chicago: Chan, Stephanie, and Djordjo Milovic. “Kuroda’s Formula and Arithmetic
    Statistics.” <i>Mathematische Zeitschrift</i>. Springer Nature, 2021. <a href="https://doi.org/10.1007/s00209-021-02823-6">https://doi.org/10.1007/s00209-021-02823-6</a>.
  ieee: S. Chan and D. Milovic, “Kuroda’s formula and arithmetic statistics,” <i>Mathematische
    Zeitschrift</i>, vol. 300, no. 2. Springer Nature, pp. 1509–1527, 2021.
  ista: Chan S, Milovic D. 2021. Kuroda’s formula and arithmetic statistics. Mathematische
    Zeitschrift. 300(2), 1509–1527.
  mla: Chan, Stephanie, and Djordjo Milovic. “Kuroda’s Formula and Arithmetic Statistics.”
    <i>Mathematische Zeitschrift</i>, vol. 300, no. 2, Springer Nature, 2021, pp.
    1509–27, doi:<a href="https://doi.org/10.1007/s00209-021-02823-6">10.1007/s00209-021-02823-6</a>.
  short: S. Chan, D. Milovic, Mathematische Zeitschrift 300 (2021) 1509–1527.
date_created: 2025-04-05T10:51:04Z
date_published: 2021-08-17T00:00:00Z
date_updated: 2025-07-10T11:51:48Z
day: '17'
doi: 10.1007/s00209-021-02823-6
extern: '1'
external_id:
  arxiv:
  - '1905.09745'
intvolume: '       300'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1905.09745
month: '08'
oa: 1
oa_version: Preprint
page: 1509-1527
publication: Mathematische Zeitschrift
publication_identifier:
  eissn:
  - 1432-1823
  issn:
  - 0025-5874
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Kuroda’s formula and arithmetic statistics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 300
year: '2021'
...
---
OA_place: repository
OA_type: green
_id: '20619'
abstract:
- lang: eng
  text: The first author’s previous work established Solomon’s WDVV-type relations
    for Welschinger’s invariant curve counts in real symplectic fourfolds by lifting
    geometric relations over possibly unorientable morphisms. We apply her framework
    to obtain WDVV-style relations for the disk invariants of real symplectic sixfolds
    with some symmetry, in particular confirming Alcolado’s prediction for P^3 and
    extending it to other spaces. These relations reduce the computation of Welschinger’s
    invariants of many real symplectic sixfolds to invariants in small degrees and
    provide lower bounds for counts of real rational curves with positive-dimensional
    insertions in some cases. In the case of P^3, our lower bounds fit perfectly with
    Kollár’s vanishing results.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Xujia
  full_name: Chen, Xujia
  id: 968ad14a-fd86-11ee-a420-ea29715511a3
  last_name: Chen
- first_name: Aleksey
  full_name: Zinger, Aleksey
  last_name: Zinger
citation:
  ama: Chen X, Zinger A. WDVV-type relations for disk Gromov–Witten invariants in
    dimension 6. <i>Mathematische Annalen</i>. 2021;379(3-4):1231-1313. doi:<a href="https://doi.org/10.1007/s00208-020-02130-1">10.1007/s00208-020-02130-1</a>
  apa: Chen, X., &#38; Zinger, A. (2021). WDVV-type relations for disk Gromov–Witten
    invariants in dimension 6. <i>Mathematische Annalen</i>. Springer Nature. <a href="https://doi.org/10.1007/s00208-020-02130-1">https://doi.org/10.1007/s00208-020-02130-1</a>
  chicago: Chen, Xujia, and Aleksey Zinger. “WDVV-Type Relations for Disk Gromov–Witten
    Invariants in Dimension 6.” <i>Mathematische Annalen</i>. Springer Nature, 2021.
    <a href="https://doi.org/10.1007/s00208-020-02130-1">https://doi.org/10.1007/s00208-020-02130-1</a>.
  ieee: X. Chen and A. Zinger, “WDVV-type relations for disk Gromov–Witten invariants
    in dimension 6,” <i>Mathematische Annalen</i>, vol. 379, no. 3–4. Springer Nature,
    pp. 1231–1313, 2021.
  ista: Chen X, Zinger A. 2021. WDVV-type relations for disk Gromov–Witten invariants
    in dimension 6. Mathematische Annalen. 379(3–4), 1231–1313.
  mla: Chen, Xujia, and Aleksey Zinger. “WDVV-Type Relations for Disk Gromov–Witten
    Invariants in Dimension 6.” <i>Mathematische Annalen</i>, vol. 379, no. 3–4, Springer
    Nature, 2021, pp. 1231–313, doi:<a href="https://doi.org/10.1007/s00208-020-02130-1">10.1007/s00208-020-02130-1</a>.
  short: X. Chen, A. Zinger, Mathematische Annalen 379 (2021) 1231–1313.
date_created: 2025-11-10T08:41:40Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2025-11-10T15:11:29Z
day: '25'
doi: 10.1007/s00208-020-02130-1
extern: '1'
external_id:
  arxiv:
  - '1904.04254'
intvolume: '       379'
issue: 3-4
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1904.04254
month: '01'
oa: 1
oa_version: Preprint
page: 1231-1313
publication: Mathematische Annalen
publication_identifier:
  eissn:
  - 1432-1807
  issn:
  - 0025-5831
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: WDVV-type relations for disk Gromov–Witten invariants in dimension 6
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 379
year: '2021'
...
---
_id: '10002'
abstract:
- lang: eng
  text: 'We present a faster symbolic algorithm for the following central problem
    in probabilistic verification: Compute the maximal end-component (MEC) decomposition
    of Markov decision processes (MDPs). This problem generalizes the SCC decomposition
    problem of graphs and closed recurrent sets of Markov chains. The model of symbolic
    algorithms is widely used in formal verification and model-checking, where access
    to the input model is restricted to only symbolic operations (e.g., basic set
    operations and computation of one-step neighborhood). For an input MDP with  n  vertices
    and  m  edges, the classical symbolic algorithm from the 1990s for the MEC decomposition
    requires  O(n2)  symbolic operations and  O(1)  symbolic space. The only other
    symbolic algorithm for the MEC decomposition requires  O(nm−−√)  symbolic operations
    and  O(m−−√)  symbolic space. A main open question is whether the worst-case  O(n2)  bound
    for symbolic operations can be beaten. We present a symbolic algorithm that requires  O˜(n1.5)  symbolic
    operations and  O˜(n−−√)  symbolic space. Moreover, the parametrization of our
    algorithm provides a trade-off between symbolic operations and symbolic space:
    for all  0<ϵ≤1/2  the symbolic algorithm requires  O˜(n2−ϵ)  symbolic operations
    and  O˜(nϵ)  symbolic space ( O˜  hides poly-logarithmic factors). Using our techniques
    we present faster algorithms for computing the almost-sure winning regions of  ω
    -regular objectives for MDPs. We consider the canonical parity objectives for  ω
    -regular objectives, and for parity objectives with  d -priorities we present
    an algorithm that computes the almost-sure winning region with  O˜(n2−ϵ)  symbolic
    operations and  O˜(nϵ)  symbolic space, for all  0<ϵ≤1/2 .'
acknowledgement: The authors are grateful to the anonymous referees for their valuable
  comments. A. S. is fully supported by the Vienna Science and Technology Fund (WWTF)
  through project ICT15–003. K. C. is supported by the Austrian Science Fund (FWF)
  NFN Grant No S11407-N23 (RiSE/SHiNE) and by the ERC CoG 863818 (ForM-SMArt). For
  M. H. the research leading to these results has received funding from the European
  Research Council under the European Unions Seventh Framework Programme (FP/2007–2013)
  / ERC Grant Agreement no. 340506.
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Wolfgang
  full_name: Dvorak, Wolfgang
  last_name: Dvorak
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Alexander
  full_name: Svozil, Alexander
  last_name: Svozil
citation:
  ama: 'Chatterjee K, Dvorak W, Henzinger M, Svozil A. Symbolic time and space tradeoffs
    for probabilistic verification. In: <i>Proceedings of the 36th Annual ACM/IEEE
    Symposium on Logic in Computer Science</i>. Institute of Electrical and Electronics
    Engineers; 2021:1-13. doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470739">10.1109/LICS52264.2021.9470739</a>'
  apa: 'Chatterjee, K., Dvorak, W., Henzinger, M., &#38; Svozil, A. (2021). Symbolic
    time and space tradeoffs for probabilistic verification. In <i>Proceedings of
    the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i> (pp. 1–13).
    Rome, Italy: Institute of Electrical and Electronics Engineers. <a href="https://doi.org/10.1109/LICS52264.2021.9470739">https://doi.org/10.1109/LICS52264.2021.9470739</a>'
  chicago: Chatterjee, Krishnendu, Wolfgang Dvorak, Monika Henzinger, and Alexander
    Svozil. “Symbolic Time and Space Tradeoffs for Probabilistic Verification.” In
    <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i>,
    1–13. Institute of Electrical and Electronics Engineers, 2021. <a href="https://doi.org/10.1109/LICS52264.2021.9470739">https://doi.org/10.1109/LICS52264.2021.9470739</a>.
  ieee: K. Chatterjee, W. Dvorak, M. Henzinger, and A. Svozil, “Symbolic time and
    space tradeoffs for probabilistic verification,” in <i>Proceedings of the 36th
    Annual ACM/IEEE Symposium on Logic in Computer Science</i>, Rome, Italy, 2021,
    pp. 1–13.
  ista: 'Chatterjee K, Dvorak W, Henzinger M, Svozil A. 2021. Symbolic time and space
    tradeoffs for probabilistic verification. Proceedings of the 36th Annual ACM/IEEE
    Symposium on Logic in Computer Science. LICS: Logic in Computer Science, 1–13.'
  mla: Chatterjee, Krishnendu, et al. “Symbolic Time and Space Tradeoffs for Probabilistic
    Verification.” <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in
    Computer Science</i>, Institute of Electrical and Electronics Engineers, 2021,
    pp. 1–13, doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470739">10.1109/LICS52264.2021.9470739</a>.
  short: K. Chatterjee, W. Dvorak, M. Henzinger, A. Svozil, in:, Proceedings of the
    36th Annual ACM/IEEE Symposium on Logic in Computer Science, Institute of Electrical
    and Electronics Engineers, 2021, pp. 1–13.
conference:
  end_date: 2021-07-02
  location: Rome, Italy
  name: 'LICS: Logic in Computer Science'
  start_date: 2021-06-29
date_created: 2021-09-12T22:01:24Z
date_published: 2021-07-07T00:00:00Z
date_updated: 2025-07-10T11:15:45Z
day: '07'
department:
- _id: KrCh
doi: 10.1109/LICS52264.2021.9470739
ec_funded: 1
external_id:
  arxiv:
  - '2104.07466'
  isi:
  - '000947350400089'
isi: 1
keyword:
- Computer science
- Computational modeling
- Markov processes
- Probabilistic logic
- Formal verification
- Game Theory
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2104.07466
month: '07'
oa: 1
oa_version: Preprint
page: 1-13
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer
  Science
publication_identifier:
  eisbn:
  - 978-1-6654-4895-6
  isbn:
  - 978-1-6654-4896-3
  issn:
  - 1043-6871
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Symbolic time and space tradeoffs for probabilistic verification
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10004'
abstract:
- lang: eng
  text: 'Markov chains are the de facto finite-state model for stochastic dynamical
    systems, and Markov decision processes (MDPs) extend Markov chains by incorporating
    non-deterministic behaviors. Given an MDP and rewards on states, a classical optimization
    criterion is the maximal expected total reward where the MDP stops after T steps,
    which can be computed by a simple dynamic programming algorithm. We consider a
    natural generalization of the problem where the stopping times can be chosen according
    to a probability distribution, such that the expected stopping time is T, to optimize
    the expected total reward. Quite surprisingly we establish inter-reducibility
    of the expected stopping-time problem for Markov chains with the Positivity problem
    (which is related to the well-known Skolem problem), for which establishing either
    decidability or undecidability would be a major breakthrough. Given the hardness
    of the exact problem, we consider the approximate version of the problem: we show
    that it can be solved in exponential time for Markov chains and in exponential
    space for MDPs.'
acknowledgement: We are grateful to the anonymous reviewers of LICS 2021 and of a
  previous version of this paper for insightful comments that helped improving the
  presentation. This research was partially supported by the grant ERC CoG 863818
  (ForM-SMArt).
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Laurent
  full_name: Doyen, Laurent
  last_name: Doyen
citation:
  ama: 'Chatterjee K, Doyen L. Stochastic processes with expected stopping time. In:
    <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i>.
    Institute of Electrical and Electronics Engineers; 2021:1-13. doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470595">10.1109/LICS52264.2021.9470595</a>'
  apa: 'Chatterjee, K., &#38; Doyen, L. (2021). Stochastic processes with expected
    stopping time. In <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic
    in Computer Science</i> (pp. 1–13). Rome, Italy: Institute of Electrical and Electronics
    Engineers. <a href="https://doi.org/10.1109/LICS52264.2021.9470595">https://doi.org/10.1109/LICS52264.2021.9470595</a>'
  chicago: Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected
    Stopping Time.” In <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic
    in Computer Science</i>, 1–13. Institute of Electrical and Electronics Engineers,
    2021. <a href="https://doi.org/10.1109/LICS52264.2021.9470595">https://doi.org/10.1109/LICS52264.2021.9470595</a>.
  ieee: K. Chatterjee and L. Doyen, “Stochastic processes with expected stopping time,”
    in <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science</i>,
    Rome, Italy, 2021, pp. 1–13.
  ista: 'Chatterjee K, Doyen L. 2021. Stochastic processes with expected stopping
    time. Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer Science.
    LICS: Logic in Computer Science, 1–13.'
  mla: Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected
    Stopping Time.” <i>Proceedings of the 36th Annual ACM/IEEE Symposium on Logic
    in Computer Science</i>, Institute of Electrical and Electronics Engineers, 2021,
    pp. 1–13, doi:<a href="https://doi.org/10.1109/LICS52264.2021.9470595">10.1109/LICS52264.2021.9470595</a>.
  short: K. Chatterjee, L. Doyen, in:, Proceedings of the 36th Annual ACM/IEEE Symposium
    on Logic in Computer Science, Institute of Electrical and Electronics Engineers,
    2021, pp. 1–13.
conference:
  end_date: 2021-07-02
  location: Rome, Italy
  name: 'LICS: Logic in Computer Science'
  start_date: 2021-06-29
date_created: 2021-09-12T22:01:25Z
date_published: 2021-07-07T00:00:00Z
date_updated: 2025-09-08T14:54:13Z
day: '07'
department:
- _id: KrCh
doi: 10.1109/LICS52264.2021.9470595
ec_funded: 1
external_id:
  arxiv:
  - '2104.07278'
  isi:
  - '000947350400036'
isi: 1
keyword:
- Computer science
- Heuristic algorithms
- Memory management
- Automata
- Markov processes
- Probability distribution
- Complexity theory
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2104.07278
month: '07'
oa: 1
oa_version: Preprint
page: 1-13
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Proceedings of the 36th Annual ACM/IEEE Symposium on Logic in Computer
  Science
publication_identifier:
  eisbn:
  - 978-1-6654-4895-6
  isbn:
  - 978-1-6654-4896-3
  issn:
  - 1043-6871
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
related_material:
  record:
  - id: '18630'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Stochastic processes with expected stopping time
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10223'
abstract:
- lang: eng
  text: Growth regulation tailors development in plants to their environment. A prominent
    example of this is the response to gravity, in which shoots bend up and roots
    bend down1. This paradox is based on opposite effects of the phytohormone auxin,
    which promotes cell expansion in shoots while inhibiting it in roots via a yet
    unknown cellular mechanism2. Here, by combining microfluidics, live imaging, genetic
    engineering and phosphoproteomics in Arabidopsis thaliana, we advance understanding
    of how auxin inhibits root growth. We show that auxin activates two distinct,
    antagonistically acting signalling pathways that converge on rapid regulation
    of apoplastic pH, a causative determinant of growth. Cell surface-based TRANSMEMBRANE
    KINASE1 (TMK1) interacts with and mediates phosphorylation and activation of plasma
    membrane H+-ATPases for apoplast acidification, while intracellular canonical
    auxin signalling promotes net cellular H+ influx, causing apoplast alkalinization.
    Simultaneous activation of these two counteracting mechanisms poises roots for
    rapid, fine-tuned growth modulation in navigating complex soil environments.
acknowledged_ssus:
- _id: LifeSc
- _id: M-Shop
- _id: Bio
acknowledgement: We thank N. Gnyliukh and L. Hörmayer for technical assistance and
  N. Paris for sharing PM-Cyto seeds. We gratefully acknowledge the Life Science,
  Machine Shop and Bioimaging Facilities of IST Austria. This project has received
  funding from the European Research Council Advanced Grant (ETAP-742985) and the
  Austrian Science Fund (FWF) under I 3630-B25 to J.F., the National Institutes of
  Health (GM067203) to W.M.G., the Netherlands Organization for Scientific Research
  (NWO; VIDI-864.13.001), Research Foundation-Flanders (FWO; Odysseus II G0D0515N)
  and a European Research Council Starting Grant (TORPEDO-714055) to W.S. and B.D.R.,
  the VICI grant (865.14.001) from the Netherlands Organization for Scientific Research
  to M.R. and D.W., the Australian Research Council and China National Distinguished
  Expert Project (WQ20174400441) to S.S., the MEXT/JSPS KAKENHI to K.T. (20K06685)
  and T.K. (20H05687 and 20H05910), the European Union’s Horizon 2020 research and
  innovation programme under Marie Skłodowska-Curie grant agreement no. 665385 and
  the DOC Fellowship of the Austrian Academy of Sciences to L.L., and the China Scholarship
  Council to J.C.
article_processing_charge: No
article_type: original
author:
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Inge
  full_name: Verstraeten, Inge
  id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
  last_name: Verstraeten
  orcid: 0000-0001-7241-2328
- first_name: Mark
  full_name: Roosjen, Mark
  last_name: Roosjen
- first_name: Koji
  full_name: Takahashi, Koji
  last_name: Takahashi
- first_name: Lesia
  full_name: Rodriguez Solovey, Lesia
  id: 3922B506-F248-11E8-B48F-1D18A9856A87
  last_name: Rodriguez Solovey
  orcid: 0000-0002-7244-7237
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Jian
  full_name: Chen, Jian
  last_name: Chen
- first_name: Lana
  full_name: Shabala, Lana
  last_name: Shabala
- first_name: Wouter
  full_name: Smet, Wouter
  last_name: Smet
- first_name: Hong
  full_name: Ren, Hong
  last_name: Ren
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
- first_name: Sergey
  full_name: Shabala, Sergey
  last_name: Shabala
- first_name: Bert
  full_name: De Rybel, Bert
  last_name: De Rybel
- first_name: Dolf
  full_name: Weijers, Dolf
  last_name: Weijers
- first_name: Toshinori
  full_name: Kinoshita, Toshinori
  last_name: Kinoshita
- first_name: William M.
  full_name: Gray, William M.
  last_name: Gray
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Li L, Verstraeten I, Roosjen M, et al. Cell surface and intracellular auxin
    signalling for H<sup>+</sup> fluxes in root growth. <i>Nature</i>. 2021;599(7884):273-277.
    doi:<a href="https://doi.org/10.1038/s41586-021-04037-6">10.1038/s41586-021-04037-6</a>
  apa: Li, L., Verstraeten, I., Roosjen, M., Takahashi, K., Rodriguez Solovey, L.,
    Merrin, J., … Friml, J. (2021). Cell surface and intracellular auxin signalling
    for H<sup>+</sup> fluxes in root growth. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/s41586-021-04037-6">https://doi.org/10.1038/s41586-021-04037-6</a>
  chicago: Li, Lanxin, Inge Verstraeten, Mark Roosjen, Koji Takahashi, Lesia Rodriguez
    Solovey, Jack Merrin, Jian Chen, et al. “Cell Surface and Intracellular Auxin
    Signalling for H<sup>+</sup> Fluxes in Root Growth.” <i>Nature</i>. Springer Nature,
    2021. <a href="https://doi.org/10.1038/s41586-021-04037-6">https://doi.org/10.1038/s41586-021-04037-6</a>.
  ieee: L. Li <i>et al.</i>, “Cell surface and intracellular auxin signalling for
    H<sup>+</sup> fluxes in root growth,” <i>Nature</i>, vol. 599, no. 7884. Springer
    Nature, pp. 273–277, 2021.
  ista: Li L, Verstraeten I, Roosjen M, Takahashi K, Rodriguez Solovey L, Merrin J,
    Chen J, Shabala L, Smet W, Ren H, Vanneste S, Shabala S, De Rybel B, Weijers D,
    Kinoshita T, Gray WM, Friml J. 2021. Cell surface and intracellular auxin signalling
    for H<sup>+</sup> fluxes in root growth. Nature. 599(7884), 273–277.
  mla: Li, Lanxin, et al. “Cell Surface and Intracellular Auxin Signalling for H<sup>+</sup>
    Fluxes in Root Growth.” <i>Nature</i>, vol. 599, no. 7884, Springer Nature, 2021,
    pp. 273–77, doi:<a href="https://doi.org/10.1038/s41586-021-04037-6">10.1038/s41586-021-04037-6</a>.
  short: L. Li, I. Verstraeten, M. Roosjen, K. Takahashi, L. Rodriguez Solovey, J.
    Merrin, J. Chen, L. Shabala, W. Smet, H. Ren, S. Vanneste, S. Shabala, B. De Rybel,
    D. Weijers, T. Kinoshita, W.M. Gray, J. Friml, Nature 599 (2021) 273–277.
corr_author: '1'
date_created: 2021-11-07T23:01:25Z
date_published: 2021-11-11T00:00:00Z
date_updated: 2025-07-10T11:49:46Z
day: '11'
department:
- _id: JiFr
- _id: NanoFab
doi: 10.1038/s41586-021-04037-6
ec_funded: 1
external_id:
  isi:
  - '000713338100006'
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intvolume: '       599'
isi: 1
issue: '7884'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
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  url: https://www.doi.org/10.21203/rs.3.rs-266395/v3
month: '11'
oa: 1
oa_version: Preprint
page: 273-277
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 26B4D67E-B435-11E9-9278-68D0E5697425
  grant_number: '25351'
  name: 'A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated
    Rapid Growth Inhibition in Arabidopsis Root'
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Webpage
    relation: press_release
    url: https://ist.ac.at/en/news/stop-and-grow/
  record:
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    status: public
scopus_import: '1'
status: public
title: Cell surface and intracellular auxin signalling for H<sup>+</sup> fluxes in
  root growth
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 599
year: '2021'
...
---
_id: '10280'
abstract:
- lang: eng
  text: 'Machines enabled the Industrial Revolution and are central to modern technological
    progress: A machine’s parts transmit forces, motion, and energy to one another
    in a predetermined manner. Today’s engineering frontier, building artificial micromachines
    that emulate the biological machinery of living organisms, requires faithful assembly
    and energy consumption at the microscale. Here, we demonstrate the programmable
    assembly of active particles into autonomous metamachines using optical templates.
    Metamachines, or machines made of machines, are stable, mobile and autonomous
    architectures, whose dynamics stems from the geometry. We use the interplay between
    anisotropic force generation of the active colloids with the control of their
    orientation by local geometry. This allows autonomous reprogramming of active
    particles of the metamachines to achieve multiple functions. It permits the modular
    assembly of metamachines by fusion, reconfiguration of metamachines and, we anticipate,
    a shift in focus of self-assembly towards active matter and reprogrammable materials.'
acknowledgement: The authors thank R. Jazzar for useful advice regarding the synthesis
  of heterodimers. We thank S. Sacanna for critical reading. This material is based
  upon work supported by the National Science Foundation under Grant No. DMR-1554724
  and Department of Army Research under grant W911NF-20-1-0112.
article_number: '6398'
article_processing_charge: Yes
article_type: original
author:
- first_name: Antoine
  full_name: Aubret, Antoine
  last_name: Aubret
- first_name: Quentin
  full_name: Martinet, Quentin
  id: b37485a8-d343-11eb-a0e9-df8c484ef8ab
  last_name: Martinet
  orcid: 0000-0002-2916-6632
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
citation:
  ama: Aubret A, Martinet Q, Palacci JA. Metamachines of pluripotent colloids. <i>Nature
    Communications</i>. 2021;12(1). doi:<a href="https://doi.org/10.1038/s41467-021-26699-6">10.1038/s41467-021-26699-6</a>
  apa: Aubret, A., Martinet, Q., &#38; Palacci, J. A. (2021). Metamachines of pluripotent
    colloids. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-021-26699-6">https://doi.org/10.1038/s41467-021-26699-6</a>
  chicago: Aubret, Antoine, Quentin Martinet, and Jérémie A Palacci. “Metamachines
    of Pluripotent Colloids.” <i>Nature Communications</i>. Springer Nature, 2021.
    <a href="https://doi.org/10.1038/s41467-021-26699-6">https://doi.org/10.1038/s41467-021-26699-6</a>.
  ieee: A. Aubret, Q. Martinet, and J. A. Palacci, “Metamachines of pluripotent colloids,”
    <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.
  ista: Aubret A, Martinet Q, Palacci JA. 2021. Metamachines of pluripotent colloids.
    Nature Communications. 12(1), 6398.
  mla: Aubret, Antoine, et al. “Metamachines of Pluripotent Colloids.” <i>Nature Communications</i>,
    vol. 12, no. 1, 6398, Springer Nature, 2021, doi:<a href="https://doi.org/10.1038/s41467-021-26699-6">10.1038/s41467-021-26699-6</a>.
  short: A. Aubret, Q. Martinet, J.A. Palacci, Nature Communications 12 (2021).
date_created: 2021-11-14T23:01:23Z
date_published: 2021-11-04T00:00:00Z
date_updated: 2023-08-14T11:48:37Z
day: '04'
ddc:
- '530'
department:
- _id: JePa
doi: 10.1038/s41467-021-26699-6
external_id:
  isi:
  - '000714754400010'
  pmid:
  - '34737315'
file:
- access_level: open_access
  checksum: 1c392b12b9b7b615d422d9fabe19cdb9
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-11-15T13:25:52Z
  date_updated: 2021-11-15T13:25:52Z
  file_id: '10292'
  file_name: 2021_NatComm_Aubret.pdf
  file_size: 6282703
  relation: main_file
  success: 1
file_date_updated: 2021-11-15T13:25:52Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Metamachines of pluripotent colloids
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
