---
OA_place: repository
OA_type: green
_id: '259'
abstract:
- lang: eng
text: "The Hasse principle and weak approximation is established for\r\nnon-singular
cubic hypersurfaces X over the function field Fq(t), provided that\r\nchar(Fq)
> 3 and X has dimension at least 6."
acknowledgement: "EP/J018260/1\tEngineering and Physical Sciences Research Council
EPSRC"
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Pankaj
full_name: Vishe, Pankaj
last_name: Vishe
citation:
ama: Browning TD, Vishe P. Rational points on cubic hypersurfaces over F_q(t) .
Geometric and Functional Analysis. 2015;25(3):671-732. doi:10.1007/s00039-015-0328-5
apa: Browning, T. D., & Vishe, P. (2015). Rational points on cubic hypersurfaces
over F_q(t) . Geometric and Functional Analysis. Springer Nature. https://doi.org/10.1007/s00039-015-0328-5
chicago: Browning, Timothy D, and Pankaj Vishe. “Rational Points on Cubic Hypersurfaces
over F_q(T) .” Geometric and Functional Analysis. Springer Nature, 2015.
https://doi.org/10.1007/s00039-015-0328-5.
ieee: T. D. Browning and P. Vishe, “Rational points on cubic hypersurfaces over
F_q(t) ,” Geometric and Functional Analysis, vol. 25, no. 3. Springer Nature,
pp. 671–732, 2015.
ista: Browning TD, Vishe P. 2015. Rational points on cubic hypersurfaces over F_q(t)
. Geometric and Functional Analysis. 25(3), 671–732.
mla: Browning, Timothy D., and Pankaj Vishe. “Rational Points on Cubic Hypersurfaces
over F_q(T) .” Geometric and Functional Analysis, vol. 25, no. 3, Springer
Nature, 2015, pp. 671–732, doi:10.1007/s00039-015-0328-5.
short: T.D. Browning, P. Vishe, Geometric and Functional Analysis 25 (2015) 671–732.
date_created: 2018-12-11T11:45:29Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2026-05-19T09:46:04Z
day: '11'
doi: 10.1007/s00039-015-0328-5
extern: '1'
external_id:
arxiv:
- '1502.00772'
intvolume: ' 25'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.1502.00772'
month: '06'
oa: 1
oa_version: Preprint
page: 671 - 732
publication: Geometric and Functional Analysis
publication_identifier:
eissn:
- 1420-8970
issn:
- 1016-443X
publication_status: published
publisher: Springer Nature
publist_id: '7643'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Rational points on cubic hypersurfaces over F_q(t) '
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 25
year: '2015'
...
---
_id: '2085'
abstract:
- lang: eng
text: 'We study the spectrum of a large system of N identical bosons interacting
via a two-body potential with strength 1/N. In this mean-field regime, Bogoliubov''s
theory predicts that the spectrum of the N-particle Hamiltonian can be approximated
by that of an effective quadratic Hamiltonian acting on Fock space, which describes
the fluctuations around a condensed state. Recently, Bogoliubov''s theory has
been justified rigorously in the case that the low-energy eigenvectors of the
N-particle Hamiltonian display complete condensation in the unique minimizer of
the corresponding Hartree functional. In this paper, we shall justify Bogoliubov''s
theory for the high-energy part of the spectrum of the N-particle Hamiltonian
corresponding to (non-linear) excited states of the Hartree functional. Moreover,
we shall extend the existing results on the excitation spectrum to the case of
non-uniqueness and/or degeneracy of the Hartree minimizer. In particular, the
latter covers the case of rotating Bose gases, when the rotation speed is large
enough to break the symmetry and to produce multiple quantized vortices in the
Hartree minimizer. '
article_processing_charge: No
arxiv: 1
author:
- first_name: Phan
full_name: Nam, Phan
id: 404092F4-F248-11E8-B48F-1D18A9856A87
last_name: Nam
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Nam P, Seiringer R. Collective excitations of Bose gases in the mean-field
regime. Archive for Rational Mechanics and Analysis. 2015;215(2):381-417.
doi:10.1007/s00205-014-0781-6
apa: Nam, P., & Seiringer, R. (2015). Collective excitations of Bose gases in
the mean-field regime. Archive for Rational Mechanics and Analysis. Springer.
https://doi.org/10.1007/s00205-014-0781-6
chicago: Nam, Phan, and Robert Seiringer. “Collective Excitations of Bose Gases
in the Mean-Field Regime.” Archive for Rational Mechanics and Analysis.
Springer, 2015. https://doi.org/10.1007/s00205-014-0781-6.
ieee: P. Nam and R. Seiringer, “Collective excitations of Bose gases in the mean-field
regime,” Archive for Rational Mechanics and Analysis, vol. 215, no. 2.
Springer, pp. 381–417, 2015.
ista: Nam P, Seiringer R. 2015. Collective excitations of Bose gases in the mean-field
regime. Archive for Rational Mechanics and Analysis. 215(2), 381–417.
mla: Nam, Phan, and Robert Seiringer. “Collective Excitations of Bose Gases in the
Mean-Field Regime.” Archive for Rational Mechanics and Analysis, vol. 215,
no. 2, Springer, 2015, pp. 381–417, doi:10.1007/s00205-014-0781-6.
short: P. Nam, R. Seiringer, Archive for Rational Mechanics and Analysis 215 (2015)
381–417.
corr_author: '1'
date_created: 2018-12-11T11:55:37Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2025-09-23T08:17:14Z
day: '01'
department:
- _id: RoSe
doi: 10.1007/s00205-014-0781-6
external_id:
arxiv:
- '1402.1153'
isi:
- '000347150400002'
intvolume: ' 215'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1402.1153
month: '02'
oa: 1
oa_version: Preprint
page: 381 - 417
publication: Archive for Rational Mechanics and Analysis
publication_status: published
publisher: Springer
publist_id: '4951'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Collective excitations of Bose gases in the mean-field regime
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 215
year: '2015'
...
---
_id: '1502'
abstract:
- lang: eng
text: We extend the theory of input-output conformance with operators for merge
and quotient. The former is useful when testing against multiple requirements
or views. The latter can be used to generate tests for patches of an already tested
system. Both operators can combine systems with different action alphabets, which
is usually the case when constructing complex systems and specifications from
parts, for instance different views as well as newly defined functionality of
a~previous version of the system.
acknowledgement: "This research was funded in part by the European Research Council
(ERC) under grant agreement 267989 (QUAREM), by the Austrian Science Fund (FWF)
projects S11402-N23(RiSE) and Z211-N23 (Wittgestein Award), by People Programme
(Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013)
under REA grant agreement 291734, and by the ARTEMIS JU under grant agreement 295373
(nSafeCer). Jan Křetínský has been partially supported by the Czech Science Foundation,
grant No. P202/12/G061. Nikola Beneš has been supported by the\r\nMEYS project
No. CZ.1.07/2.3.00/30.0009 Employment of Newly Graduated Doctors of Science for
Scientific Excellence."
alternative_title:
- 'Proceedings of the 18th International ACM SIGSOFT Symposium on Component-Based
Software Engineering '
article_processing_charge: No
author:
- first_name: Nikola
full_name: Beneš, Nikola
last_name: Beneš
- first_name: Przemyslaw
full_name: Daca, Przemyslaw
id: 49351290-F248-11E8-B48F-1D18A9856A87
last_name: Daca
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Dejan
full_name: Nickovic, Dejan
last_name: Nickovic
citation:
ama: 'Beneš N, Daca P, Henzinger TA, Kretinsky J, Nickovic D. Complete composition
operators for IOCO-testing theory. In: ACM; 2015:101-110. doi:10.1145/2737166.2737175'
apa: 'Beneš, N., Daca, P., Henzinger, T. A., Kretinsky, J., & Nickovic, D. (2015).
Complete composition operators for IOCO-testing theory (pp. 101–110). Presented
at the CBSE: Component-Based Software Engineering , Montreal, QC, Canada: ACM.
https://doi.org/10.1145/2737166.2737175'
chicago: Beneš, Nikola, Przemyslaw Daca, Thomas A Henzinger, Jan Kretinsky, and
Dejan Nickovic. “Complete Composition Operators for IOCO-Testing Theory,” 101–10.
ACM, 2015. https://doi.org/10.1145/2737166.2737175.
ieee: 'N. Beneš, P. Daca, T. A. Henzinger, J. Kretinsky, and D. Nickovic, “Complete
composition operators for IOCO-testing theory,” presented at the CBSE: Component-Based
Software Engineering , Montreal, QC, Canada, 2015, pp. 101–110.'
ista: 'Beneš N, Daca P, Henzinger TA, Kretinsky J, Nickovic D. 2015. Complete composition
operators for IOCO-testing theory. CBSE: Component-Based Software Engineering
, Proceedings of the 18th International ACM SIGSOFT Symposium on Component-Based
Software Engineering , , 101–110.'
mla: Beneš, Nikola, et al. Complete Composition Operators for IOCO-Testing Theory.
ACM, 2015, pp. 101–10, doi:10.1145/2737166.2737175.
short: N. Beneš, P. Daca, T.A. Henzinger, J. Kretinsky, D. Nickovic, in:, ACM, 2015,
pp. 101–110.
conference:
end_date: 2015-05-08
location: Montreal, QC, Canada
name: 'CBSE: Component-Based Software Engineering '
start_date: 2015-05-04
date_created: 2018-12-11T11:52:24Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2026-04-15T10:02:12Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1145/2737166.2737175
ec_funded: 1
external_id:
isi:
- '000380554800013'
file:
- access_level: open_access
checksum: c6ce681035c163a158751f240cb7d389
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:46Z
date_updated: 2020-07-14T12:44:59Z
file_id: '5303'
file_name: IST-2016-625-v1+1_conf-cbse-BenesDHKN15.pdf
file_size: 467561
relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 101 - 110
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: Formal methods for the design and analysis of complex systems
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_identifier:
isbn:
- 978-1-4503-3471-6
publication_status: published
publisher: ACM
publist_id: '5676'
pubrep_id: '625'
quality_controlled: '1'
related_material:
record:
- id: '1155'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Complete composition operators for IOCO-testing theory
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2015'
...
---
_id: '1530'
abstract:
- lang: eng
text: In growing cells, protein synthesis and cell growth are typically not synchronous,
and, thus, protein concentrations vary over the cell division cycle. We have developed
a theoretical description of genetic regulatory systems in bacteria that explicitly
considers the cell division cycle to investigate its impact on gene expression.
We calculate the cell-to-cell variations arising from cells being at different
stages in the division cycle for unregulated genes and for basic regulatory mechanisms.
These variations contribute to the extrinsic noise observed in single-cell experiments,
and are most significant for proteins with short lifetimes. Negative autoregulation
buffers against variation of protein concentration over the division cycle, but
the effect is found to be relatively weak. Stronger buffering is achieved by an
increased protein lifetime. Positive autoregulation can strongly amplify such
variation if the parameters are set to values that lead to resonance-like behaviour.
For cooperative positive autoregulation, the concentration variation over the
division cycle diminishes the parameter region of bistability and modulates the
switching times between the two stable states. The same effects are seen for a
two-gene mutual-repression toggle switch. By contrast, an oscillatory circuit,
the repressilator, is only weakly affected by the division cycle.
article_number: '066003'
article_processing_charge: No
author:
- first_name: Veronika
full_name: Bierbaum, Veronika
id: 3FD04378-F248-11E8-B48F-1D18A9856A87
last_name: Bierbaum
- first_name: Stefan
full_name: Klumpp, Stefan
last_name: Klumpp
citation:
ama: Bierbaum V, Klumpp S. Impact of the cell division cycle on gene circuits. Physical
Biology. 2015;12(6). doi:10.1088/1478-3975/12/6/066003
apa: Bierbaum, V., & Klumpp, S. (2015). Impact of the cell division cycle on
gene circuits. Physical Biology. IOP Publishing. https://doi.org/10.1088/1478-3975/12/6/066003
chicago: Bierbaum, Veronika, and Stefan Klumpp. “Impact of the Cell Division Cycle
on Gene Circuits.” Physical Biology. IOP Publishing, 2015. https://doi.org/10.1088/1478-3975/12/6/066003.
ieee: V. Bierbaum and S. Klumpp, “Impact of the cell division cycle on gene circuits,”
Physical Biology, vol. 12, no. 6. IOP Publishing, 2015.
ista: Bierbaum V, Klumpp S. 2015. Impact of the cell division cycle on gene circuits.
Physical Biology. 12(6), 066003.
mla: Bierbaum, Veronika, and Stefan Klumpp. “Impact of the Cell Division Cycle on
Gene Circuits.” Physical Biology, vol. 12, no. 6, 066003, IOP Publishing,
2015, doi:10.1088/1478-3975/12/6/066003.
short: V. Bierbaum, S. Klumpp, Physical Biology 12 (2015).
corr_author: '1'
date_created: 2018-12-11T11:52:33Z
date_published: 2015-09-25T00:00:00Z
date_updated: 2025-09-23T09:19:53Z
day: '25'
department:
- _id: MiSi
doi: 10.1088/1478-3975/12/6/066003
external_id:
isi:
- '000368186300009'
intvolume: ' 12'
isi: 1
issue: '6'
language:
- iso: eng
month: '09'
oa_version: None
publication: Physical Biology
publication_status: published
publisher: IOP Publishing
publist_id: '5641'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Impact of the cell division cycle on gene circuits
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 12
year: '2015'
...
---
_id: '1536'
abstract:
- lang: eng
text: Strigolactones, first discovered as germination stimulants for parasitic weeds
[1], are carotenoid-derived phytohormones that play major roles in inhibiting
lateral bud outgrowth and promoting plant-mycorrhizal symbiosis [2-4]. Furthermore,
strigolactones are involved in the regulation of lateral and adventitious root
development, root cell division [5, 6], secondary growth [7], and leaf senescence
[8]. Recently, we discovered the strigolactone transporter Petunia axillaris PLEIOTROPIC
DRUG RESISTANCE 1 (PaPDR1), which is required for efficient mycorrhizal colonization
and inhibition of lateral bud outgrowth [9]. However, how strigolactones are transported
through the plant remained unknown. Here we show that PaPDR1 exhibits a cell-type-specific
asymmetric localization in different root tissues. In root tips, PaPDR1 is co-expressed
with the strigolactone biosynthetic gene DAD1 (CCD8), and it is localized at the
apical membrane of root hypodermal cells, presumably mediating the shootward transport
of strigolactone. Above the root tip, in the hypodermal passage cells that form
gates for the entry of mycorrhizal fungi, PaPDR1 is present in the outer-lateral
membrane, compatible with its postulated function as strigolactone exporter from
root to soil. Transport studies are in line with our localization studies since
(1) a papdr1 mutant displays impaired transport of strigolactones out of the root
tip to the shoot as well as into the rhizosphere and (2) DAD1 expression and PIN1/PIN2
levels change in plants deregulated for PDR1 expression, suggestive of variations
in endogenous strigolactone contents. In conclusion, our results indicate that
the polar localizations of PaPDR1 mediate directional shootward strigolactone
transport as well as localized exudation into the soil.
acknowledgement: "This work was funded by a grant of the Swiss National Foundation
to E.M.\r\nWe thank Dr. José María Mateos (University of Zurich) for providing us
with the vibratome, Prof. Dolf Weijers (Wageningen University, the Netherlands)
for shipping us his set of ligation-independent cloning vectors, Prof. Bruno Humbel
(University of Lausanne) for suggestions on GFP-PDR1 detection, and Dr. Undine Krügel
(University of Zurich) and Prof. Michal Jasinski (Polish Academy of Science) for
hints on protein quantification."
article_processing_charge: No
author:
- first_name: Joëlle
full_name: Sasse, Joëlle
last_name: Sasse
- first_name: Sibu
full_name: Simon, Sibu
id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
last_name: Simon
orcid: 0000-0002-1998-6741
- first_name: Christian
full_name: Gübeli, Christian
last_name: Gübeli
- first_name: Guowei
full_name: Liu, Guowei
last_name: Liu
- first_name: Xi
full_name: Cheng, Xi
last_name: Cheng
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Harro
full_name: Bouwmeester, Harro
last_name: Bouwmeester
- first_name: Enrico
full_name: Martinoia, Enrico
last_name: Martinoia
- first_name: Lorenzo
full_name: Borghi, Lorenzo
last_name: Borghi
citation:
ama: Sasse J, Simon S, Gübeli C, et al. Asymmetric localizations of the ABC transporter
PaPDR1 trace paths of directional strigolactone transport. Current Biology.
2015;25(5):647-655. doi:10.1016/j.cub.2015.01.015
apa: Sasse, J., Simon, S., Gübeli, C., Liu, G., Cheng, X., Friml, J., … Borghi,
L. (2015). Asymmetric localizations of the ABC transporter PaPDR1 trace paths
of directional strigolactone transport. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2015.01.015
chicago: Sasse, Joëlle, Sibu Simon, Christian Gübeli, Guowei Liu, Xi Cheng, Jiří
Friml, Harro Bouwmeester, Enrico Martinoia, and Lorenzo Borghi. “Asymmetric Localizations
of the ABC Transporter PaPDR1 Trace Paths of Directional Strigolactone Transport.”
Current Biology. Cell Press, 2015. https://doi.org/10.1016/j.cub.2015.01.015.
ieee: J. Sasse et al., “Asymmetric localizations of the ABC transporter PaPDR1
trace paths of directional strigolactone transport,” Current Biology, vol.
25, no. 5. Cell Press, pp. 647–655, 2015.
ista: Sasse J, Simon S, Gübeli C, Liu G, Cheng X, Friml J, Bouwmeester H, Martinoia
E, Borghi L. 2015. Asymmetric localizations of the ABC transporter PaPDR1 trace
paths of directional strigolactone transport. Current Biology. 25(5), 647–655.
mla: Sasse, Joëlle, et al. “Asymmetric Localizations of the ABC Transporter PaPDR1
Trace Paths of Directional Strigolactone Transport.” Current Biology, vol.
25, no. 5, Cell Press, 2015, pp. 647–55, doi:10.1016/j.cub.2015.01.015.
short: J. Sasse, S. Simon, C. Gübeli, G. Liu, X. Cheng, J. Friml, H. Bouwmeester,
E. Martinoia, L. Borghi, Current Biology 25 (2015) 647–655.
date_created: 2018-12-11T11:52:35Z
date_published: 2015-02-12T00:00:00Z
date_updated: 2025-09-23T07:57:02Z
day: '12'
department:
- _id: JiFr
doi: 10.1016/j.cub.2015.01.015
external_id:
isi:
- '000350708800029'
intvolume: ' 25'
isi: 1
issue: '5'
language:
- iso: eng
month: '02'
oa_version: None
page: 647 - 655
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '5635'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Asymmetric localizations of the ABC transporter PaPDR1 trace paths of directional
strigolactone transport
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 25
year: '2015'
...
---
_id: '1541'
abstract:
- lang: eng
text: We present XSpeed a parallel state-space exploration algorithm for continuous
systems with linear dynamics and nondeterministic inputs. The motivation of having
parallel algorithms is to exploit the computational power of multi-core processors
to speed-up performance. The parallelization is achieved on two fronts. First,
we propose a parallel implementation of the support function algorithm by sampling
functions in parallel. Second, we propose a parallel state-space exploration by
slicing the time horizon and computing the reachable states in the time slices
in parallel. The second method can be however applied only to a class of linear
systems with invertible dynamics and fixed input. A GP-GPU implementation is also
presented following a lazy evaluation strategy on support functions. The parallel
algorithms are implemented in the tool XSpeed. We evaluated the performance on
two benchmarks including an 28 dimension Helicopter model. Comparison with the
sequential counterpart shows a maximum speed-up of almost 7× on a 6 core, 12 thread
Intel Xeon CPU E5-2420 processor. Our GP-GPU implementation shows a maximum speed-up
of 12× over the sequential implementation and 53× over SpaceEx (LGG scenario),
the state of the art tool for reachability analysis of linear hybrid systems.
Experiments illustrate that our parallel algorithm with time slicing not only
speeds-up performance but also improves precision.
acknowledgement: This work was supported in part by the European Research Council
(ERC) under grant 267989 (QUAREM) and by the Austrian Science Fund (FWF) under grants
S11402-N23, S11405-N23 and S11412-N23 (RiSE/SHiNE) and Z211-N23 (Wittgenstein Award).
alternative_title:
- LNCS
author:
- first_name: Rajarshi
full_name: Ray, Rajarshi
last_name: Ray
- first_name: Amit
full_name: Gurung, Amit
last_name: Gurung
- first_name: Binayak
full_name: Das, Binayak
last_name: Das
- first_name: Ezio
full_name: Bartocci, Ezio
last_name: Bartocci
- first_name: Sergiy
full_name: Bogomolov, Sergiy
id: 369D9A44-F248-11E8-B48F-1D18A9856A87
last_name: Bogomolov
orcid: 0000-0002-0686-0365
- first_name: Radu
full_name: Grosu, Radu
last_name: Grosu
citation:
ama: 'Ray R, Gurung A, Das B, Bartocci E, Bogomolov S, Grosu R. XSpeed: Accelerating
reachability analysis on multi-core processors. 2015;9434:3-18. doi:10.1007/978-3-319-26287-1_1'
apa: 'Ray, R., Gurung, A., Das, B., Bartocci, E., Bogomolov, S., & Grosu, R.
(2015). XSpeed: Accelerating reachability analysis on multi-core processors. Presented
at the HVC: Haifa Verification Conference, Haifa, Israel: Springer. https://doi.org/10.1007/978-3-319-26287-1_1'
chicago: 'Ray, Rajarshi, Amit Gurung, Binayak Das, Ezio Bartocci, Sergiy Bogomolov,
and Radu Grosu. “XSpeed: Accelerating Reachability Analysis on Multi-Core Processors.”
Lecture Notes in Computer Science. Springer, 2015. https://doi.org/10.1007/978-3-319-26287-1_1.'
ieee: 'R. Ray, A. Gurung, B. Das, E. Bartocci, S. Bogomolov, and R. Grosu, “XSpeed:
Accelerating reachability analysis on multi-core processors,” vol. 9434. Springer,
pp. 3–18, 2015.'
ista: 'Ray R, Gurung A, Das B, Bartocci E, Bogomolov S, Grosu R. 2015. XSpeed: Accelerating
reachability analysis on multi-core processors. 9434, 3–18.'
mla: 'Ray, Rajarshi, et al. XSpeed: Accelerating Reachability Analysis on Multi-Core
Processors. Vol. 9434, Springer, 2015, pp. 3–18, doi:10.1007/978-3-319-26287-1_1.'
short: R. Ray, A. Gurung, B. Das, E. Bartocci, S. Bogomolov, R. Grosu, 9434 (2015)
3–18.
conference:
end_date: 2015-11-19
location: Haifa, Israel
name: 'HVC: Haifa Verification Conference'
start_date: 2015-11-17
date_created: 2018-12-11T11:52:37Z
date_published: 2015-11-28T00:00:00Z
date_updated: 2025-04-15T06:26:02Z
day: '28'
department:
- _id: ToHe
doi: 10.1007/978-3-319-26287-1_1
ec_funded: 1
intvolume: ' 9434'
language:
- iso: eng
month: '11'
oa_version: None
page: 3 - 18
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: Formal methods for the design and analysis of complex systems
publication_status: published
publisher: Springer
publist_id: '5630'
quality_controlled: '1'
scopus_import: 1
series_title: Lecture Notes in Computer Science
status: public
title: 'XSpeed: Accelerating reachability analysis on multi-core processors'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9434
year: '2015'
...
---
_id: '1549'
abstract:
- lang: eng
text: Nature has incorporated small photochromic molecules, colloquially termed
'photoswitches', in photoreceptor proteins to sense optical cues in photo-taxis
and vision. While Nature's ability to employ light-responsive functionalities
has long been recognized, it was not until recently that scientists designed,
synthesized and applied synthetic photochromes to manipulate many of which open
rapidly and locally in their native cell types, biological processes with the
temporal and spatial resolution of light. Ion channels in particular have come
to the forefront of proteins that can be put under the designer control of synthetic
photochromes. Photochromic ion channel controllers are comprised of three classes,
photochromic soluble ligands (PCLs), photochromic tethered ligands (PTLs) and
photochromic crosslinkers (PXs), and in each class ion channel functionality is
controlled through reversible changes in photochrome structure. By acting as light-dependent
ion channel agonists, antagonist or modulators, photochromic controllers effectively
converted a wide range of ion channels, including voltage-gated ion channels,
'leak channels', tri-, tetra- and pentameric ligand-gated ion channels, and temperaturesensitive
ion channels, into man-made photoreceptors. Control by photochromes can be reversible,
unlike in the case of 'caged' compounds, and non-invasive with high spatial precision,
unlike pharmacology and electrical manipulation. Here, we introduce design principles
of emerging photochromic molecules that act on ion channels and discuss the impact
that these molecules are beginning to have on ion channel biophysics and neuronal
physiology.
article_processing_charge: No
author:
- first_name: Catherine
full_name: Mckenzie, Catherine
id: 3EEDE19A-F248-11E8-B48F-1D18A9856A87
last_name: Mckenzie
- first_name: Inmaculada
full_name: Sanchez Romero, Inmaculada
id: 3D9C5D30-F248-11E8-B48F-1D18A9856A87
last_name: Sanchez Romero
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: 'Mckenzie C, Sanchez-Romero I, Janovjak HL. Flipping the photoswitch: Ion channels
under light control. In: Novel Chemical Tools to Study Ion Channel Biology.
Vol 869. Advances in Experimental Medicine and Biology. Springer; 2015:101-117.
doi:10.1007/978-1-4939-2845-3_6'
apa: 'Mckenzie, C., Sanchez-Romero, I., & Janovjak, H. L. (2015). Flipping the
photoswitch: Ion channels under light control. In Novel chemical tools to study
ion channel biology (Vol. 869, pp. 101–117). Springer. https://doi.org/10.1007/978-1-4939-2845-3_6'
chicago: 'Mckenzie, Catherine, Inmaculada Sanchez-Romero, and Harald L Janovjak.
“Flipping the Photoswitch: Ion Channels under Light Control.” In Novel Chemical
Tools to Study Ion Channel Biology, 869:101–17. Advances in Experimental Medicine
and Biology. Springer, 2015. https://doi.org/10.1007/978-1-4939-2845-3_6.'
ieee: 'C. Mckenzie, I. Sanchez-Romero, and H. L. Janovjak, “Flipping the photoswitch:
Ion channels under light control,” in Novel chemical tools to study ion channel
biology, vol. 869, Springer, 2015, pp. 101–117.'
ista: 'Mckenzie C, Sanchez-Romero I, Janovjak HL. 2015.Flipping the photoswitch:
Ion channels under light control. In: Novel chemical tools to study ion channel
biology. vol. 869, 101–117.'
mla: 'Mckenzie, Catherine, et al. “Flipping the Photoswitch: Ion Channels under
Light Control.” Novel Chemical Tools to Study Ion Channel Biology, vol.
869, Springer, 2015, pp. 101–17, doi:10.1007/978-1-4939-2845-3_6.'
short: C. Mckenzie, I. Sanchez-Romero, H.L. Janovjak, in:, Novel Chemical Tools
to Study Ion Channel Biology, Springer, 2015, pp. 101–117.
corr_author: '1'
date_created: 2018-12-11T11:52:39Z
date_published: 2015-09-18T00:00:00Z
date_updated: 2025-09-23T08:52:05Z
day: '18'
ddc:
- '571'
- '576'
department:
- _id: HaJa
doi: 10.1007/978-1-4939-2845-3_6
external_id:
isi:
- '000361794300006'
file:
- access_level: open_access
checksum: bd1bfdf2423a0c3b6e7cabfa8b44bc0f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:02Z
date_updated: 2020-07-14T12:45:01Z
file_id: '4854'
file_name: IST-2017-839-v1+1_mckenzie.pdf
file_size: 1919655
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 869'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 101 - 117
publication: Novel chemical tools to study ion channel biology
publication_identifier:
isbn:
- 978-1-4939-2844-6
publication_status: published
publisher: Springer
publist_id: '5622'
pubrep_id: '839'
quality_controlled: '1'
scopus_import: '1'
series_title: Advances in Experimental Medicine and Biology
status: public
title: 'Flipping the photoswitch: Ion channels under light control'
type: book_chapter
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 869
year: '2015'
...
---
_id: '1878'
abstract:
- lang: eng
text: Petrocoptis is a small genus of chasmophytic plants endemic to the Iberian
Peninsula, with some localized populations in the French Pyrenees. Within the
genus, a dozen species have been recognized based on morphological diversity,
most of them with limited distribution area, in small populations and frequently
with potential threats to their survival. To date, however, a molecular evaluation
of the current systematic treatments has not been carried out. The aim of the
present study is to infer phylogenetic relationships among its subordinate taxa
by using plastidial rps16 intron and nuclear internal transcribed spacer (ITS)
DNA sequences; and evaluate the phylogenetic placement of the genus Petrocoptis
within the family Caryophyllaceae. The monophyly of Petrocoptis is supported by
both ITS and rps16 intron sequence analyses. Furthermore, time estimates using
BEAST analyses indicate a Middle to Late Miocene diversification (10.59 Myr, 6.44–15.26
Myr highest posterior densities [HPD], for ITS; 14.30 Myr, 8.61–21.00 Myr HPD,
for rps16 intron).
article_processing_charge: No
author:
- first_name: Eduardo
full_name: Cires Rodriguez, Eduardo
id: 2AD56A7A-F248-11E8-B48F-1D18A9856A87
last_name: Cires Rodriguez
- first_name: José
full_name: Prieto, José
last_name: Prieto
citation:
ama: Cires Rodriguez E, Prieto J. Phylogenetic relationships of Petrocoptis A. Braun
ex Endl. (Caryophyllaceae), a discussed genus from the Iberian Peninsula. Journal
of Plant Research. 2015;128(2):223-238. doi:10.1007/s10265-014-0691-6
apa: Cires Rodriguez, E., & Prieto, J. (2015). Phylogenetic relationships of
Petrocoptis A. Braun ex Endl. (Caryophyllaceae), a discussed genus from the Iberian
Peninsula. Journal of Plant Research. Springer. https://doi.org/10.1007/s10265-014-0691-6
chicago: Cires Rodriguez, Eduardo, and José Prieto. “Phylogenetic Relationships
of Petrocoptis A. Braun Ex Endl. (Caryophyllaceae), a Discussed Genus from the
Iberian Peninsula.” Journal of Plant Research. Springer, 2015. https://doi.org/10.1007/s10265-014-0691-6.
ieee: E. Cires Rodriguez and J. Prieto, “Phylogenetic relationships of Petrocoptis
A. Braun ex Endl. (Caryophyllaceae), a discussed genus from the Iberian Peninsula,”
Journal of Plant Research, vol. 128, no. 2. Springer, pp. 223–238, 2015.
ista: Cires Rodriguez E, Prieto J. 2015. Phylogenetic relationships of Petrocoptis
A. Braun ex Endl. (Caryophyllaceae), a discussed genus from the Iberian Peninsula.
Journal of Plant Research. 128(2), 223–238.
mla: Cires Rodriguez, Eduardo, and José Prieto. “Phylogenetic Relationships of Petrocoptis
A. Braun Ex Endl. (Caryophyllaceae), a Discussed Genus from the Iberian Peninsula.”
Journal of Plant Research, vol. 128, no. 2, Springer, 2015, pp. 223–38,
doi:10.1007/s10265-014-0691-6.
short: E. Cires Rodriguez, J. Prieto, Journal of Plant Research 128 (2015) 223–238.
corr_author: '1'
date_created: 2018-12-11T11:54:30Z
date_published: 2015-01-24T00:00:00Z
date_updated: 2025-09-23T09:49:04Z
day: '24'
department:
- _id: JiFr
doi: 10.1007/s10265-014-0691-6
external_id:
isi:
- '000350826000001'
intvolume: ' 128'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 223 - 238
publication: Journal of Plant Research
publication_status: published
publisher: Springer
publist_id: '5217'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phylogenetic relationships of Petrocoptis A. Braun ex Endl. (Caryophyllaceae),
a discussed genus from the Iberian Peninsula
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 128
year: '2015'
...
---
_id: '1834'
abstract:
- lang: eng
text: Huge body of evidences demonstrated that volatile anesthetics affect the hippocampal
neurogenesis and neurocognitive functions, and most of them showed impairment
at anesthetic dose. Here, we investigated the effect of low dose (1.8%) sevoflurane
on hippocampal neurogenesis and dentate gyrus-dependent learning. Neonatal rats
at postnatal day 4 to 6 (P4-6) were treated with 1.8% sevoflurane for 6 hours.
Neurogenesis was quantified by bromodeoxyuridine labeling and electrophysiology
recording. Four and seven weeks after treatment, the Morris water maze and contextual-fear
discrimination learning tests were performed to determine the influence on spatial
learning and pattern separation. A 6-hour treatment with 1.8% sevoflurane promoted
hippocampal neurogenesis and increased the survival of newborn cells and the proportion
of immature granular cells in the dentate gyrus of neonatal rats. Sevoflurane-treated
rats performed better during the training days of the Morris water maze test and
in contextual-fear discrimination learning test. These results suggest that a
subanesthetic dose of sevoflurane promotes hippocampal neurogenesis in neonatal
rats and facilitates their performance in dentate gyrus-dependent learning tasks.
article_processing_charge: No
article_type: original
author:
- first_name: Chong
full_name: Chen, Chong
id: 3DFD581A-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Chao
full_name: Wang, Chao
last_name: Wang
- first_name: Xuan
full_name: Zhao, Xuan
last_name: Zhao
- first_name: Tao
full_name: Zhou, Tao
last_name: Zhou
- first_name: Dao
full_name: Xu, Dao
last_name: Xu
- first_name: Zhi
full_name: Wang, Zhi
last_name: Wang
- first_name: Ying
full_name: Wang, Ying
last_name: Wang
citation:
ama: Chen C, Wang C, Zhao X, et al. Low-dose sevoflurane promoteshippocampal neurogenesis
and facilitates the development of dentate gyrus-dependent learning in neonatal
rats. ASN Neuro. 2015;7(2). doi:10.1177/1759091415575845
apa: Chen, C., Wang, C., Zhao, X., Zhou, T., Xu, D., Wang, Z., & Wang, Y. (2015).
Low-dose sevoflurane promoteshippocampal neurogenesis and facilitates the development
of dentate gyrus-dependent learning in neonatal rats. ASN Neuro. SAGE Publications.
https://doi.org/10.1177/1759091415575845
chicago: Chen, Chong, Chao Wang, Xuan Zhao, Tao Zhou, Dao Xu, Zhi Wang, and Ying
Wang. “Low-Dose Sevoflurane Promoteshippocampal Neurogenesis and Facilitates the
Development of Dentate Gyrus-Dependent Learning in Neonatal Rats.” ASN Neuro.
SAGE Publications, 2015. https://doi.org/10.1177/1759091415575845.
ieee: C. Chen et al., “Low-dose sevoflurane promoteshippocampal neurogenesis
and facilitates the development of dentate gyrus-dependent learning in neonatal
rats,” ASN Neuro, vol. 7, no. 2. SAGE Publications, 2015.
ista: Chen C, Wang C, Zhao X, Zhou T, Xu D, Wang Z, Wang Y. 2015. Low-dose sevoflurane
promoteshippocampal neurogenesis and facilitates the development of dentate gyrus-dependent
learning in neonatal rats. ASN Neuro. 7(2).
mla: Chen, Chong, et al. “Low-Dose Sevoflurane Promoteshippocampal Neurogenesis
and Facilitates the Development of Dentate Gyrus-Dependent Learning in Neonatal
Rats.” ASN Neuro, vol. 7, no. 2, SAGE Publications, 2015, doi:10.1177/1759091415575845.
short: C. Chen, C. Wang, X. Zhao, T. Zhou, D. Xu, Z. Wang, Y. Wang, ASN Neuro 7
(2015).
date_created: 2018-12-11T11:54:16Z
date_published: 2015-04-13T00:00:00Z
date_updated: 2025-09-23T09:31:50Z
day: '13'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1177/1759091415575845
external_id:
isi:
- '000353223200002'
file:
- access_level: open_access
checksum: 53e16bd3fc2ae2c0d7de9164626c37aa
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:08Z
date_updated: 2020-07-14T12:45:18Z
file_id: '5057'
file_name: IST-2016-456-v1+1_ASN_Neuro-2015-Chen-.pdf
file_size: 1146814
relation: main_file
file_date_updated: 2020-07-14T12:45:18Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
issue: '2'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '04'
oa: 1
oa_version: Published Version
publication: ASN Neuro
publication_status: published
publisher: SAGE Publications
publist_id: '5269'
pubrep_id: '456'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Low-dose sevoflurane promoteshippocampal neurogenesis and facilitates the development
of dentate gyrus-dependent learning in neonatal rats
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
short: CC BY (3.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 7
year: '2015'
...
---
_id: '11967'
abstract:
- lang: eng
text: An experimentally easy to perform method for the generation of alumina-supported
Fe3O4 nanoparticles [(6±1) nm size, 0.67 wt %]and the use of this material in
hydrazine-mediated heterogeneously catalyzed reductions of nitroarenes to anilines
under batch and continuous-flow conditions is presented. The bench-stable, reusable
nano-Fe3O4@Al2O3 catalyst can selectively reduce functionalized nitroarenes at
1 mol % catalyst loading by using a 20 mol % excess of hydrazine hydrate in an
elevated temperature regime (150 °C, reaction time 2–6 min in batch). For continuous-flow
processing, the catalyst material is packed into dedicated cartridges and used
in a commercially available high-temperature/-pressure flow device. In continuous
mode, reaction times can be reduced to less than 1 min at 150 °C (30 bar back
pressure) in a highly intensified process. The nano-Fe3O4@Al2O3 catalyst demonstrated
stable reduction of nitrobenzene (0.5 M in MeOH) for more than 10 h on stream
at a productivity of 30 mmol h−1 (0.72 mol per day). Importantly, virtually no
leaching of the catalytically active material could be observed by inductively
coupled plasma MS monitoring.
article_processing_charge: No
article_type: original
author:
- first_name: Mojtaba Mirhosseini
full_name: Moghaddam, Mojtaba Mirhosseini
last_name: Moghaddam
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Toma
full_name: Glasnov, Toma
last_name: Glasnov
- first_name: C. Oliver
full_name: Kappe, C. Oliver
last_name: Kappe
citation:
ama: Moghaddam MM, Pieber B, Glasnov T, Kappe CO. Immobilized iron oxide nanoparticles
as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous
flow. ChemSusChem. 2014;7(11):3122-3131. doi:10.1002/cssc.201402455
apa: Moghaddam, M. M., Pieber, B., Glasnov, T., & Kappe, C. O. (2014). Immobilized
iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated
nitro reductions in continuous flow. ChemSusChem. Wiley. https://doi.org/10.1002/cssc.201402455
chicago: Moghaddam, Mojtaba Mirhosseini, Bartholomäus Pieber, Toma Glasnov, and
C. Oliver Kappe. “Immobilized Iron Oxide Nanoparticles as Stable and Reusable
Catalysts for Hydrazine-Mediated Nitro Reductions in Continuous Flow.” ChemSusChem.
Wiley, 2014. https://doi.org/10.1002/cssc.201402455.
ieee: M. M. Moghaddam, B. Pieber, T. Glasnov, and C. O. Kappe, “Immobilized iron
oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro
reductions in continuous flow,” ChemSusChem, vol. 7, no. 11. Wiley, pp.
3122–3131, 2014.
ista: Moghaddam MM, Pieber B, Glasnov T, Kappe CO. 2014. Immobilized iron oxide
nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions
in continuous flow. ChemSusChem. 7(11), 3122–3131.
mla: Moghaddam, Mojtaba Mirhosseini, et al. “Immobilized Iron Oxide Nanoparticles
as Stable and Reusable Catalysts for Hydrazine-Mediated Nitro Reductions in Continuous
Flow.” ChemSusChem, vol. 7, no. 11, Wiley, 2014, pp. 3122–31, doi:10.1002/cssc.201402455.
short: M.M. Moghaddam, B. Pieber, T. Glasnov, C.O. Kappe, ChemSusChem 7 (2014) 3122–3131.
date_created: 2022-08-25T08:36:54Z
date_published: 2014-11-01T00:00:00Z
date_updated: 2023-02-21T10:09:42Z
day: '01'
doi: 10.1002/cssc.201402455
extern: '1'
external_id:
pmid:
- '25209099'
intvolume: ' 7'
issue: '11'
language:
- iso: eng
month: '11'
oa_version: None
page: 3122-3131
pmid: 1
publication: ChemSusChem
publication_identifier:
eissn:
- 1864-564X
issn:
- 1864-5631
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated
nitro reductions in continuous flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2014'
...
---
_id: '2227'
abstract:
- lang: eng
text: The Balkan Peninsula, characterized by high rates of endemism, is recognised
as one of the most diverse and species-rich areas of Europe. However, little is
known about the origin of Balkan endemics. The present study addresses the phylogenetic
position of the Balkan endemic Ranunculus wettsteinii, as well as its taxonomic
status and relationship with the widespread R. parnassiifolius, based on nuclear
DNA (internal transcribed spacer, ITS) and plastid regions (rpl32-trnL, rps16-trnQ,
trnK-matK and ycf6-psbM). Maximum parsimony and Bayesian inference analyses revealed
a well-supported clade formed by accessions of R. wettsteinii. Furthermore, our
phylogenetic and network analyses supported previous hypotheses of a likely allopolyploid
origin for R. wettsteinii between R. montenegrinus and R. parnassiifolius, with
the latter as the maternal parent.
article_processing_charge: No
author:
- first_name: Eduardo
full_name: Cires Rodriguez, Eduardo
id: 2AD56A7A-F248-11E8-B48F-1D18A9856A87
last_name: Cires Rodriguez
- first_name: Matthias
full_name: Baltisberger, Matthias
last_name: Baltisberger
- first_name: Candela
full_name: Cuesta, Candela
id: 33A3C818-F248-11E8-B48F-1D18A9856A87
last_name: Cuesta
orcid: 0000-0003-1923-2410
- first_name: Pablo
full_name: Vargas, Pablo
last_name: Vargas
- first_name: José
full_name: Prieto, José
last_name: Prieto
citation:
ama: Cires Rodriguez E, Baltisberger M, Cuesta C, Vargas P, Prieto J. Allopolyploid
origin of the Balkan endemic Ranunculus wettsteinii (Ranunculaceae) inferred from
nuclear and plastid DNA sequences. Organisms Diversity and Evolution. 2014;14(1):1-10.
doi:10.1007/s13127-013-0150-6
apa: Cires Rodriguez, E., Baltisberger, M., Cuesta, C., Vargas, P., & Prieto,
J. (2014). Allopolyploid origin of the Balkan endemic Ranunculus wettsteinii (Ranunculaceae)
inferred from nuclear and plastid DNA sequences. Organisms Diversity and Evolution.
Springer. https://doi.org/10.1007/s13127-013-0150-6
chicago: Cires Rodriguez, Eduardo, Matthias Baltisberger, Candela Cuesta, Pablo
Vargas, and José Prieto. “Allopolyploid Origin of the Balkan Endemic Ranunculus
Wettsteinii (Ranunculaceae) Inferred from Nuclear and Plastid DNA Sequences.”
Organisms Diversity and Evolution. Springer, 2014. https://doi.org/10.1007/s13127-013-0150-6.
ieee: E. Cires Rodriguez, M. Baltisberger, C. Cuesta, P. Vargas, and J. Prieto,
“Allopolyploid origin of the Balkan endemic Ranunculus wettsteinii (Ranunculaceae)
inferred from nuclear and plastid DNA sequences,” Organisms Diversity and Evolution,
vol. 14, no. 1. Springer, pp. 1–10, 2014.
ista: Cires Rodriguez E, Baltisberger M, Cuesta C, Vargas P, Prieto J. 2014. Allopolyploid
origin of the Balkan endemic Ranunculus wettsteinii (Ranunculaceae) inferred from
nuclear and plastid DNA sequences. Organisms Diversity and Evolution. 14(1), 1–10.
mla: Cires Rodriguez, Eduardo, et al. “Allopolyploid Origin of the Balkan Endemic
Ranunculus Wettsteinii (Ranunculaceae) Inferred from Nuclear and Plastid DNA Sequences.”
Organisms Diversity and Evolution, vol. 14, no. 1, Springer, 2014, pp.
1–10, doi:10.1007/s13127-013-0150-6.
short: E. Cires Rodriguez, M. Baltisberger, C. Cuesta, P. Vargas, J. Prieto, Organisms
Diversity and Evolution 14 (2014) 1–10.
corr_author: '1'
date_created: 2018-12-11T11:56:26Z
date_published: 2014-03-01T00:00:00Z
date_updated: 2025-09-29T11:25:37Z
day: '01'
department:
- _id: JiFr
- _id: EvBe
doi: 10.1007/s13127-013-0150-6
external_id:
isi:
- '000332585400001'
intvolume: ' 14'
isi: 1
issue: '1'
language:
- iso: eng
month: '03'
oa_version: None
page: 1 - 10
publication: Organisms Diversity and Evolution
publication_identifier:
issn:
- 1439-6092
publication_status: published
publisher: Springer
publist_id: '4734'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Allopolyploid origin of the Balkan endemic Ranunculus wettsteinii (Ranunculaceae)
inferred from nuclear and plastid DNA sequences
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 14
year: '2014'
...
---
_id: '252'
abstract:
- lang: eng
text: For any number field k, upper bounds are established for the number of k-rational
points of bounded height on non-singular del Pezzo surfaces defined over k, which
are equipped with suitable conic bundle structures over k.
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Michael
full_name: Jones, Michael S
last_name: Jones
citation:
ama: Browning TD, Jones M. Counting rational points on del Pezzo surfaces with a
conic bundle structure. Acta Arithmetica. 2014;163(3):271-298. doi:10.4064/aa163-3-6
apa: Browning, T. D., & Jones, M. (2014). Counting rational points on del Pezzo
surfaces with a conic bundle structure. Acta Arithmetica. Instytut Matematyczny.
https://doi.org/10.4064/aa163-3-6
chicago: Browning, Timothy D, and Michael Jones. “Counting Rational Points on Del
Pezzo Surfaces with a Conic Bundle Structure.” Acta Arithmetica. Instytut
Matematyczny, 2014. https://doi.org/10.4064/aa163-3-6.
ieee: T. D. Browning and M. Jones, “Counting rational points on del Pezzo surfaces
with a conic bundle structure,” Acta Arithmetica, vol. 163, no. 3. Instytut
Matematyczny, pp. 271–298, 2014.
ista: Browning TD, Jones M. 2014. Counting rational points on del Pezzo surfaces
with a conic bundle structure. Acta Arithmetica. 163(3), 271–298.
mla: Browning, Timothy D., and Michael Jones. “Counting Rational Points on Del Pezzo
Surfaces with a Conic Bundle Structure.” Acta Arithmetica, vol. 163, no.
3, Instytut Matematyczny, 2014, pp. 271–98, doi:10.4064/aa163-3-6.
short: T.D. Browning, M. Jones, Acta Arithmetica 163 (2014) 271–298.
date_created: 2018-12-11T11:45:26Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:57:59Z
day: '01'
doi: 10.4064/aa163-3-6
extern: 1
intvolume: ' 163'
issue: '3'
month: '01'
page: 271 - 298
publication: Acta Arithmetica
publication_status: published
publisher: Instytut Matematyczny
publist_id: '7650'
quality_controlled: 0
status: public
title: Counting rational points on del Pezzo surfaces with a conic bundle structure
type: journal_article
volume: 163
year: '2014'
...
---
_id: '2716'
abstract:
- lang: eng
text: Multi-dimensional mean-payoff and energy games provide the mathematical foundation
for the quantitative study of reactive systems, and play a central role in the
emerging quantitative theory of verification and synthesis. In this work, we study
the strategy synthesis problem for games with such multi-dimensional objectives
along with a parity condition, a canonical way to express ω ω -regular conditions.
While in general, the winning strategies in such games may require infinite memory,
for synthesis the most relevant problem is the construction of a finite-memory
winning strategy (if one exists). Our main contributions are as follows. First,
we show a tight exponential bound (matching upper and lower bounds) on the memory
required for finite-memory winning strategies in both multi-dimensional mean-payoff
and energy games along with parity objectives. This significantly improves the
triple exponential upper bound for multi energy games (without parity) that could
be derived from results in literature for games on vector addition systems with
states. Second, we present an optimal symbolic and incremental algorithm to compute
a finite-memory winning strategy (if one exists) in such games. Finally, we give
a complete characterization of when finite memory of strategies can be traded
off for randomness. In particular, we show that for one-dimension mean-payoff
parity games, randomized memoryless strategies are as powerful as their pure finite-memory
counterparts.
acknowledgement: "Krishnendu Chatterjee is supported by Austrian Science Fund (FWF)
Grant No P 23499-N23, FWF NFN Grant No S11407 (RiSE), ERC Starting Grant (279307:
Graph Games) and Microsoft faculty fellowship. Mickael Randour is supported by F.R.S.-FNRS.
fellowship. \r\nJean-François Raskin is supported by ERC Starting Grant (279499:
inVEST).Thanks to D. Sbabo for useful pointers, V. Bruyère for comments on a preliminary
draft, and A. Bohy for fruitful discussions about the Acacia+ tool. We are grateful
to the anonymous reviewers for their insightful comments. "
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Mickael
full_name: Randour, Mickael
last_name: Randour
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
citation:
ama: Chatterjee K, Randour M, Raskin J. Strategy synthesis for multi-dimensional
quantitative objectives. Acta Informatica. 2014;51(3-4):129-163. doi:10.1007/s00236-013-0182-6
apa: Chatterjee, K., Randour, M., & Raskin, J. (2014). Strategy synthesis for
multi-dimensional quantitative objectives. Acta Informatica. Springer.
https://doi.org/10.1007/s00236-013-0182-6
chicago: Chatterjee, Krishnendu, Mickael Randour, and Jean Raskin. “Strategy Synthesis
for Multi-Dimensional Quantitative Objectives.” Acta Informatica. Springer,
2014. https://doi.org/10.1007/s00236-013-0182-6.
ieee: K. Chatterjee, M. Randour, and J. Raskin, “Strategy synthesis for multi-dimensional
quantitative objectives,” Acta Informatica, vol. 51, no. 3–4. Springer,
pp. 129–163, 2014.
ista: Chatterjee K, Randour M, Raskin J. 2014. Strategy synthesis for multi-dimensional
quantitative objectives. Acta Informatica. 51(3–4), 129–163.
mla: Chatterjee, Krishnendu, et al. “Strategy Synthesis for Multi-Dimensional Quantitative
Objectives.” Acta Informatica, vol. 51, no. 3–4, Springer, 2014, pp. 129–63,
doi:10.1007/s00236-013-0182-6.
short: K. Chatterjee, M. Randour, J. Raskin, Acta Informatica 51 (2014) 129–163.
date_created: 2018-12-11T11:59:14Z
date_published: 2014-06-01T00:00:00Z
date_updated: 2025-09-29T11:10:44Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/s00236-013-0182-6
external_id:
arxiv:
- '1201.5073'
isi:
- '000335981500002'
intvolume: ' 51'
isi: 1
issue: 3-4
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1201.5073
month: '06'
oa: 1
oa_version: Preprint
page: 129 - 163
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
publication: Acta Informatica
publication_status: published
publisher: Springer
publist_id: '4176'
quality_controlled: '1'
related_material:
record:
- id: '10904'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Strategy synthesis for multi-dimensional quantitative objectives
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 51
year: '2014'
...
---
_id: '2178'
abstract:
- lang: eng
text: We consider the three-state toric homogeneous Markov chain model (THMC) without
loops and initial parameters. At time T, the size of the design matrix is 6 ×
3 · 2T-1 and the convex hull of its columns is the model polytope. We study the
behavior of this polytope for T ≥ 3 and we show that it is defined by 24 facets
for all T ≥ 5. Moreover, we give a complete description of these facets. From
this, we deduce that the toric ideal associated with the design matrix is generated
by binomials of degree at most 6. Our proof is based on a result due to Sturmfels,
who gave a bound on the degree of the generators of a toric ideal, provided the
normality of the corresponding toric variety. In our setting, we established the
normality of the toric variety associated to the THMC model by studying the geometric
properties of the model polytope.
acknowledgement: Research of Martín del Campo supported in part by NSF Grant DMS-915211.
article_processing_charge: No
arxiv: 1
author:
- first_name: David
full_name: Haws, David
last_name: Haws
- first_name: Abraham
full_name: Martin Del Campo Sanchez, Abraham
id: 4CF47F6A-F248-11E8-B48F-1D18A9856A87
last_name: Martin Del Campo Sanchez
- first_name: Akimichi
full_name: Takemura, Akimichi
last_name: Takemura
- first_name: Ruriko
full_name: Yoshida, Ruriko
last_name: Yoshida
citation:
ama: Haws D, Martin del Campo Sanchez A, Takemura A, Yoshida R. Markov degree of
the three-state toric homogeneous Markov chain model. Beitrage zur Algebra
und Geometrie. 2014;55(1):161-188. doi:10.1007/s13366-013-0178-y
apa: Haws, D., Martin del Campo Sanchez, A., Takemura, A., & Yoshida, R. (2014).
Markov degree of the three-state toric homogeneous Markov chain model. Beitrage
Zur Algebra Und Geometrie. Springer. https://doi.org/10.1007/s13366-013-0178-y
chicago: Haws, David, Abraham Martin del Campo Sanchez, Akimichi Takemura, and Ruriko
Yoshida. “Markov Degree of the Three-State Toric Homogeneous Markov Chain Model.”
Beitrage Zur Algebra Und Geometrie. Springer, 2014. https://doi.org/10.1007/s13366-013-0178-y.
ieee: D. Haws, A. Martin del Campo Sanchez, A. Takemura, and R. Yoshida, “Markov
degree of the three-state toric homogeneous Markov chain model,” Beitrage zur
Algebra und Geometrie, vol. 55, no. 1. Springer, pp. 161–188, 2014.
ista: Haws D, Martin del Campo Sanchez A, Takemura A, Yoshida R. 2014. Markov degree
of the three-state toric homogeneous Markov chain model. Beitrage zur Algebra
und Geometrie. 55(1), 161–188.
mla: Haws, David, et al. “Markov Degree of the Three-State Toric Homogeneous Markov
Chain Model.” Beitrage Zur Algebra Und Geometrie, vol. 55, no. 1, Springer,
2014, pp. 161–88, doi:10.1007/s13366-013-0178-y.
short: D. Haws, A. Martin del Campo Sanchez, A. Takemura, R. Yoshida, Beitrage Zur
Algebra Und Geometrie 55 (2014) 161–188.
date_created: 2018-12-11T11:56:10Z
date_published: 2014-03-01T00:00:00Z
date_updated: 2025-06-11T07:59:53Z
day: '01'
department:
- _id: CaUh
doi: 10.1007/s13366-013-0178-y
external_id:
arxiv:
- '1204.3070'
intvolume: ' 55'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1204.3070
month: '03'
oa: 1
oa_version: Submitted Version
page: 161 - 188
publication: Beitrage zur Algebra und Geometrie
publication_status: published
publisher: Springer
publist_id: '4804'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Markov degree of the three-state toric homogeneous Markov chain model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2014'
...
---
OA_place: publisher
_id: '1404'
abstract:
- lang: eng
text: "The co-evolution of hosts and pathogens is characterized by continuous adaptations
of both parties. Pathogens of social insects need to adapt towards disease defences
at two levels: 1) individual immunity of each colony member consisting of behavioural
defence strategies as well as humoral and cellular immune responses and 2) social
immunity that is collectively performed by all group members comprising behavioural,
physiological and organisational defence strategies.\r\n\r\nTo disentangle the
selection pressure on pathogens by the collective versus individual level of disease
defence in social insects, we performed an evolution experiment using the Argentine
Ant, Linepithema humile, as a host and a mixture of the general insect pathogenic
fungus Metarhizium spp. (6 strains) as a pathogen. We allowed pathogen evolution
over 10 serial host passages to two different evolution host treatments: (1) only
individual host immunity in a single host treatment, and (2) simultaneously acting
individual and social immunity in a social host treatment, in which an exposed
ant was accompanied by two untreated nestmates.\r\n\r\nBefore starting the pathogen
evolution experiment, the 6 Metarhizium spp. strains were characterised concerning
conidiospore size killing rates in singly and socially reared ants, their competitiveness
under coinfecting conditions and their influence on ant behaviour. We analysed
how the ancestral atrain mixture changed in conidiospere size, killing rate and
strain composition dependent on host treatment (single or social hosts) during
10 passages and found that killing rate and conidiospere size of the pathogen
increased under both evolution regimes, but different depending on host treatment.\r\n\r\nTesting
the evolved strain mixtures that evolved under either the single or social host
treatment under both single and social current rearing conditions in a full factorial
design experiment revealed that the additional collective defences in insect societies
add new selection pressure for their coevolving pathogens that compromise their
ability to adapt to its host at the group level. To our knowledge, this is the
first study directly measuring the influence of social immunity on pathogen evolution."
acknowledgement: This work was funded by the DFG and the ERC.
alternative_title:
- IST Austria Thesis
article_processing_charge: No
author:
- first_name: Miriam
full_name: Stock, Miriam
id: 42462816-F248-11E8-B48F-1D18A9856A87
last_name: Stock
citation:
ama: Stock M. Evolution of a fungal pathogen towards individual versus social immunity
in ants. 2014.
apa: Stock, M. (2014). Evolution of a fungal pathogen towards individual versus
social immunity in ants. IST Austria.
chicago: Stock, Miriam. “Evolution of a Fungal Pathogen towards Individual versus
Social Immunity in Ants.” IST Austria, 2014.
ieee: M. Stock, “Evolution of a fungal pathogen towards individual versus social
immunity in ants,” IST Austria, 2014.
ista: Stock M. 2014. Evolution of a fungal pathogen towards individual versus social
immunity in ants. IST Austria.
mla: Stock, Miriam. Evolution of a Fungal Pathogen towards Individual versus
Social Immunity in Ants. IST Austria, 2014.
short: M. Stock, Evolution of a Fungal Pathogen towards Individual versus Social
Immunity in Ants, IST Austria, 2014.
corr_author: '1'
date_created: 2018-12-11T11:51:49Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2026-04-09T14:33:27Z
day: '01'
department:
- _id: SyCr
language:
- iso: eng
month: '04'
oa_version: None
page: '101'
publication_status: published
publisher: IST Austria
publist_id: '5803'
status: public
supervisor:
- first_name: Sylvia M
full_name: Cremer, Sylvia M
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
title: Evolution of a fungal pathogen towards individual versus social immunity in
ants
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2014'
...
---
_id: '1913'
abstract:
- lang: eng
text: 'Deposits of phosphorylated tau protein and convergence of pathology in the
hippocampus are the hallmarks of neurodegenerative tauopathies. Thus we aimed
to evaluate whether regional and cellular vulnerability patterns in the hippocampus
distinguish tauopathies or are influenced by their concomitant presence. Methods:
We created a heat map of phospho-tau (AT8) immunoreactivity patterns in 24 hippocampal
subregions/layers in individuals with Alzheimer''s disease (AD)-related neurofibrillary
degeneration (n = 40), Pick''s disease (n = 8), progressive supranuclear palsy
(n = 7), corticobasal degeneration (n = 6), argyrophilic grain disease (AGD, n
= 18), globular glial tauopathy (n = 5), and tau-astrogliopathy of the elderly
(n = 10). AT8 immunoreactivity patterns were compared by mathematical analysis.
Results: Our study reveals disease-specific hot spots and regional selective vulnerability
for these disorders. The pattern of hippocampal AD-related tau pathology is strongly
influenced by concomitant AGD. Mathematical analysis reveals that hippocampal
involvement in primary tauopathies is distinguishable from early-stage AD-related
neurofibrillary degeneration. Conclusion: Our data demonstrate disease-specific
AT8 immunoreactivity patterns and hot spots in the hippocampus even in tauopathies,
which primarily do not affect the hippocampus. These hot spots can be shifted
to other regions by the co-occurrence of tauopathies like AGD. Our observations
support the notion that globular glial tauopathies and tau-astrogliopathy of the
elderly are distinct entities.'
acknowledgement: This study was supported by the European Commission’s 7th Framework
Programme under GA No. 278486, ‘DEVELAGE’.
article_processing_charge: No
article_type: original
author:
- first_name: Ivan
full_name: Milenković, Ivan
last_name: Milenković
- first_name: Tatjana
full_name: Petrov, Tatjana
id: 3D5811FC-F248-11E8-B48F-1D18A9856A87
last_name: Petrov
orcid: 0000-0002-9041-0905
- first_name: Gábor
full_name: Kovács, Gábor
last_name: Kovács
citation:
ama: Milenković I, Petrov T, Kovács G. Patterns of hippocampal tau pathology differentiate
neurodegenerative dementias. Dementia and Geriatric Cognitive Disorders.
2014;38(5-6):375-388. doi:10.1159/000365548
apa: Milenković, I., Petrov, T., & Kovács, G. (2014). Patterns of hippocampal
tau pathology differentiate neurodegenerative dementias. Dementia and Geriatric
Cognitive Disorders. Karger Publishers. https://doi.org/10.1159/000365548
chicago: Milenković, Ivan, Tatjana Petrov, and Gábor Kovács. “Patterns of Hippocampal
Tau Pathology Differentiate Neurodegenerative Dementias.” Dementia and Geriatric
Cognitive Disorders. Karger Publishers, 2014. https://doi.org/10.1159/000365548.
ieee: I. Milenković, T. Petrov, and G. Kovács, “Patterns of hippocampal tau pathology
differentiate neurodegenerative dementias,” Dementia and Geriatric Cognitive
Disorders, vol. 38, no. 5–6. Karger Publishers, pp. 375–388, 2014.
ista: Milenković I, Petrov T, Kovács G. 2014. Patterns of hippocampal tau pathology
differentiate neurodegenerative dementias. Dementia and Geriatric Cognitive Disorders.
38(5–6), 375–388.
mla: Milenković, Ivan, et al. “Patterns of Hippocampal Tau Pathology Differentiate
Neurodegenerative Dementias.” Dementia and Geriatric Cognitive Disorders,
vol. 38, no. 5–6, Karger Publishers, 2014, pp. 375–88, doi:10.1159/000365548.
short: I. Milenković, T. Petrov, G. Kovács, Dementia and Geriatric Cognitive Disorders
38 (2014) 375–388.
date_created: 2018-12-11T11:54:41Z
date_published: 2014-11-07T00:00:00Z
date_updated: 2026-06-18T18:13:04Z
day: '07'
ddc:
- '570'
department:
- _id: CaGu
doi: 10.1159/000365548
external_id:
isi:
- '000344049900011'
pmid:
- '25195847'
intvolume: ' 38'
isi: 1
issue: 5-6
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://kops.uni-konstanz.de/bitstream/123456789/42127/1/Milenkovic_2-17ivylo2up0798.pdf
month: '11'
oa: 1
oa_version: Published Version
page: 375 - 388
pmid: 1
publication: Dementia and Geriatric Cognitive Disorders
publication_identifier:
issn:
- 1420-8008
publication_status: published
publisher: Karger Publishers
publist_id: '5181'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Patterns of hippocampal tau pathology differentiate neurodegenerative dementias
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2014'
...
---
_id: '1923'
abstract:
- lang: eng
text: We derive the equations for a thin, axisymmetric elastic shell subjected to
an internal active stress giving rise to active tension and moments within the
shell. We discuss the stability of a cylindrical elastic shell and its response
to a localized change in internal active stress. This description is relevant
to describe the cellular actomyosin cortex, a thin shell at the cell surface behaving
elastically at a short timescale and subjected to active internal forces arising
from myosin molecular motor activity. We show that the recent observations of
cell deformation following detachment of adherent cells (Maître J-L et al 2012
Science 338 253-6) are well accounted for by this mechanical description. The
actin cortex elastic and bending moduli can be obtained from a quantitative analysis
of cell shapes observed in these experiments. Our approach thus provides a non-invasive,
imaging-based method for the extraction of cellular physical parameters.
article_number: '065005'
article_processing_charge: No
author:
- first_name: Hélène
full_name: Berthoumieux, Hélène
last_name: Berthoumieux
- first_name: Jean-Léon
full_name: Maître, Jean-Léon
id: 48F1E0D8-F248-11E8-B48F-1D18A9856A87
last_name: Maître
orcid: 0000-0002-3688-1474
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Ewa
full_name: Paluch, Ewa
last_name: Paluch
- first_name: Frank
full_name: Julicher, Frank
last_name: Julicher
- first_name: Guillaume
full_name: Salbreux, Guillaume
last_name: Salbreux
citation:
ama: Berthoumieux H, Maître J-L, Heisenberg C-PJ, Paluch E, Julicher F, Salbreux
G. Active elastic thin shell theory for cellular deformations. New Journal
of Physics. 2014;16. doi:10.1088/1367-2630/16/6/065005
apa: Berthoumieux, H., Maître, J.-L., Heisenberg, C.-P. J., Paluch, E., Julicher,
F., & Salbreux, G. (2014). Active elastic thin shell theory for cellular deformations.
New Journal of Physics. IOP Publishing. https://doi.org/10.1088/1367-2630/16/6/065005
chicago: Berthoumieux, Hélène, Jean-Léon Maître, Carl-Philipp J Heisenberg, Ewa
Paluch, Frank Julicher, and Guillaume Salbreux. “Active Elastic Thin Shell Theory
for Cellular Deformations.” New Journal of Physics. IOP Publishing, 2014.
https://doi.org/10.1088/1367-2630/16/6/065005.
ieee: H. Berthoumieux, J.-L. Maître, C.-P. J. Heisenberg, E. Paluch, F. Julicher,
and G. Salbreux, “Active elastic thin shell theory for cellular deformations,”
New Journal of Physics, vol. 16. IOP Publishing, 2014.
ista: Berthoumieux H, Maître J-L, Heisenberg C-PJ, Paluch E, Julicher F, Salbreux
G. 2014. Active elastic thin shell theory for cellular deformations. New Journal
of Physics. 16, 065005.
mla: Berthoumieux, Hélène, et al. “Active Elastic Thin Shell Theory for Cellular
Deformations.” New Journal of Physics, vol. 16, 065005, IOP Publishing,
2014, doi:10.1088/1367-2630/16/6/065005.
short: H. Berthoumieux, J.-L. Maître, C.-P.J. Heisenberg, E. Paluch, F. Julicher,
G. Salbreux, New Journal of Physics 16 (2014).
date_created: 2018-12-11T11:54:44Z
date_published: 2014-06-01T00:00:00Z
date_updated: 2025-09-29T12:16:30Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1088/1367-2630/16/6/065005
external_id:
isi:
- '000339083700003'
file:
- access_level: open_access
checksum: 8dbe81ec656bf1264d8889bda9b2b985
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:16Z
date_updated: 2020-07-14T12:45:21Z
file_id: '5202'
file_name: IST-2016-429-v1+1_document.pdf
file_size: 941387
relation: main_file
file_date_updated: 2020-07-14T12:45:21Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: New Journal of Physics
publication_status: published
publisher: IOP Publishing
publist_id: '5171'
pubrep_id: '429'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active elastic thin shell theory for cellular deformations
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 16
year: '2014'
...
---
_id: '2022'
abstract:
- lang: eng
text: Radial glial progenitors (RGPs) are responsible for producing nearly all neocortical
neurons. To gain insight into the patterns of RGP division and neuron production,
we quantitatively analyzed excitatory neuron genesis in the mouse neocortex using
Mosaic Analysis with Double Markers, which provides single-cell resolution of
progenitor division patterns and potential in vivo. We found that RGPs progress
through a coherent program in which their proliferative potential diminishes in
a predictable manner. Upon entry into the neurogenic phase, individual RGPs produce
∼8–9 neurons distributed in both deep and superficial layers, indicating a unitary
output in neuronal production. Removal of OTX1, a transcription factor transiently
expressed in RGPs, results in both deep- and superficial-layer neuron loss and
a reduction in neuronal unit size. Moreover, ∼1/6 of neurogenic RGPs proceed to
produce glia. These results suggest that progenitor behavior and histogenesis
in the mammalian neocortex conform to a remarkably orderly and deterministic program.
article_processing_charge: No
author:
- first_name: Peng
full_name: Gao, Peng
last_name: Gao
- first_name: Maria P
full_name: Postiglione, Maria P
id: 2C67902A-F248-11E8-B48F-1D18A9856A87
last_name: Postiglione
- first_name: Teresa
full_name: Krieger, Teresa
last_name: Krieger
- first_name: Luisirene
full_name: Hernandez, Luisirene
last_name: Hernandez
- first_name: Chao
full_name: Wang, Chao
last_name: Wang
- first_name: Zhi
full_name: Han, Zhi
last_name: Han
- first_name: Carmen
full_name: Streicher, Carmen
id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
last_name: Streicher
- first_name: Ekaterina
full_name: Papusheva, Ekaterina
id: 41DB591E-F248-11E8-B48F-1D18A9856A87
last_name: Papusheva
- first_name: Ryan
full_name: Insolera, Ryan
last_name: Insolera
- first_name: Kritika
full_name: Chugh, Kritika
last_name: Chugh
- first_name: Oren
full_name: Kodish, Oren
last_name: Kodish
- first_name: Kun
full_name: Huang, Kun
last_name: Huang
- first_name: Benjamin
full_name: Simons, Benjamin
last_name: Simons
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Song
full_name: Shi, Song
last_name: Shi
citation:
ama: Gao P, Postiglione MP, Krieger T, et al. Deterministic progenitor behavior
and unitary production of neurons in the neocortex. Cell. 2014;159(4):775-788.
doi:10.1016/j.cell.2014.10.027
apa: Gao, P., Postiglione, M. P., Krieger, T., Hernandez, L., Wang, C., Han, Z.,
… Shi, S. (2014). Deterministic progenitor behavior and unitary production of
neurons in the neocortex. Cell. Cell Press. https://doi.org/10.1016/j.cell.2014.10.027
chicago: Gao, Peng, Maria P Postiglione, Teresa Krieger, Luisirene Hernandez, Chao
Wang, Zhi Han, Carmen Streicher, et al. “Deterministic Progenitor Behavior and
Unitary Production of Neurons in the Neocortex.” Cell. Cell Press, 2014.
https://doi.org/10.1016/j.cell.2014.10.027.
ieee: P. Gao et al., “Deterministic progenitor behavior and unitary production
of neurons in the neocortex,” Cell, vol. 159, no. 4. Cell Press, pp. 775–788,
2014.
ista: Gao P, Postiglione MP, Krieger T, Hernandez L, Wang C, Han Z, Streicher C,
Papusheva E, Insolera R, Chugh K, Kodish O, Huang K, Simons B, Luo L, Hippenmeyer
S, Shi S. 2014. Deterministic progenitor behavior and unitary production of neurons
in the neocortex. Cell. 159(4), 775–788.
mla: Gao, Peng, et al. “Deterministic Progenitor Behavior and Unitary Production
of Neurons in the Neocortex.” Cell, vol. 159, no. 4, Cell Press, 2014,
pp. 775–88, doi:10.1016/j.cell.2014.10.027.
short: P. Gao, M.P. Postiglione, T. Krieger, L. Hernandez, C. Wang, Z. Han, C. Streicher,
E. Papusheva, R. Insolera, K. Chugh, O. Kodish, K. Huang, B. Simons, L. Luo, S.
Hippenmeyer, S. Shi, Cell 159 (2014) 775–788.
corr_author: '1'
date_created: 2018-12-11T11:55:16Z
date_published: 2014-11-06T00:00:00Z
date_updated: 2025-09-29T11:57:49Z
day: '06'
ddc:
- '570'
department:
- _id: SiHi
- _id: Bio
doi: 10.1016/j.cell.2014.10.027
ec_funded: 1
external_id:
isi:
- '000344522000011'
file:
- access_level: open_access
checksum: 6c5de8329bb2ffa71cba9fda750f14ce
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:47Z
date_updated: 2020-07-14T12:45:25Z
file_id: '4709'
file_name: IST-2016-423-v1+1_1-s2.0-S0092867414013154-main.pdf
file_size: 4435787
relation: main_file
file_date_updated: 2020-07-14T12:45:25Z
has_accepted_license: '1'
intvolume: ' 159'
isi: 1
issue: '4'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 775 - 788
project:
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618444'
name: Molecular Mechanisms of Cerebral Cortex Development
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
grant_number: RGP0053/2014
name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
Level
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '5050'
pubrep_id: '423'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deterministic progenitor behavior and unitary production of neurons in the
neocortex
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 159
year: '2014'
...
---
_id: '17642'
abstract:
- lang: eng
text: The presence of quasars at redshifts z > 6 indicates the existence of supermassive
black holes (SMBHs) as massive as a few times 10^9 Msun, challenging models for
SMBH formation. One pathway is through the direct collapse of gas in T_{vir} >
10^4 K halos; however, this requires the suppression of H_2 cooling to prevent
fragmentation. In this paper, we examine a proposed new mechanism for this suppression
which relies on cold-mode accretion flows leading to shocks at high densities
(n > 10^4 cm^{-3}) and temperatures (T > 10^4 K). In such gas, H_2 is efficiently
collisionally dissociated. We use high-resolution numerical simulations to test
this idea, demonstrating that such halos typically have lower temperature progenitors,
in which cooling is efficient. Those halos do show filamentary flows; however,
the gas shocks at or near the virial radius (at low densities), thus preventing
the proposed collisional mechanism from operating. We do find that, if we artificially
suppress H_2 formation with a high UV background, so as to allow gas in the halo
center to enter the high-temperature, high-density "zone of no return", it will
remain there even if the UV flux is turned off, collapsing to high density at
high temperature. Due to computational limitations, we simulated only three halos.
However, we demonstrate, using Monte Carlo calculations of 10^6 halo merger histories,
that a few rare halos could assemble rapidly enough to avoid efficient H_2 cooling
in all of their progenitor halos, provided that the UV background exceeds J_{21}
~ few at redshifts as high as z ~ 20
article_processing_charge: No
article_type: original
author:
- first_name: Ricardo
full_name: Fernandez, Ricardo
last_name: Fernandez
- first_name: Greg L.
full_name: Bryan, Greg L.
last_name: Bryan
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Miao
full_name: Li, Miao
last_name: Li
citation:
ama: 'Fernandez R, Bryan GL, Haiman Z, Li M. H2 suppression with shocking inflows:
Testing a pathway for supermassive black hole formation. Monthly Notices of
the Royal Astronomical Society. 2014;439(4):3798-3807. doi:10.1093/mnras/stu230'
apa: 'Fernandez, R., Bryan, G. L., Haiman, Z., & Li, M. (2014). H2 suppression
with shocking inflows: Testing a pathway for supermassive black hole formation.
Monthly Notices of the Royal Astronomical Society. Oxford University Press.
https://doi.org/10.1093/mnras/stu230'
chicago: 'Fernandez, Ricardo, Greg L. Bryan, Zoltán Haiman, and Miao Li. “H2 Suppression
with Shocking Inflows: Testing a Pathway for Supermassive Black Hole Formation.”
Monthly Notices of the Royal Astronomical Society. Oxford University Press,
2014. https://doi.org/10.1093/mnras/stu230.'
ieee: 'R. Fernandez, G. L. Bryan, Z. Haiman, and M. Li, “H2 suppression with shocking
inflows: Testing a pathway for supermassive black hole formation,” Monthly
Notices of the Royal Astronomical Society, vol. 439, no. 4. Oxford University
Press, pp. 3798–3807, 2014.'
ista: 'Fernandez R, Bryan GL, Haiman Z, Li M. 2014. H2 suppression with shocking
inflows: Testing a pathway for supermassive black hole formation. Monthly Notices
of the Royal Astronomical Society. 439(4), 3798–3807.'
mla: 'Fernandez, Ricardo, et al. “H2 Suppression with Shocking Inflows: Testing
a Pathway for Supermassive Black Hole Formation.” Monthly Notices of the Royal
Astronomical Society, vol. 439, no. 4, Oxford University Press, 2014, pp.
3798–807, doi:10.1093/mnras/stu230.'
short: R. Fernandez, G.L. Bryan, Z. Haiman, M. Li, Monthly Notices of the Royal
Astronomical Society 439 (2014) 3798–3807.
date_created: 2024-09-06T07:21:52Z
date_published: 2014-02-26T00:00:00Z
date_updated: 2024-09-24T11:56:43Z
day: '26'
doi: 10.1093/mnras/stu230
extern: '1'
intvolume: ' 439'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/mnras/stu230
month: '02'
oa: 1
oa_version: Published Version
page: 3798-3807
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
issn:
- 1365-2966
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'H2 suppression with shocking inflows: Testing a pathway for supermassive black
hole formation'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 439
year: '2014'
...
---
_id: '17643'
abstract:
- lang: eng
text: Explaining the existence of supermassive black holes (SMBHs) larger than ∼10^9M⊙
at redshifts z>∼6 remains an open theoretical question. One possibility is that
gas collapsing rapidly in pristine atomic cooling halos (Tvir>∼10^4K) produces
10^4−10^6M⊙ black holes. Previous studies have shown that the formation of such
a black hole requires a strong UV background to prevent molecular hydrogen cooling
and gas fragmentation. Recently it has been proposed that a high UV background
may not be required for halos that accrete material extremely rapidly or for halos
where gas cooling is delayed due to a high baryon-dark matter streaming velocity.
In this work, we point out that building up a halo with Tvir>∼104K before molecular
cooling becomes efficient is not sufficient for forming a direct collapse black
hole (DCBH). Though molecular hydrogen formation may be delayed, it will eventually
form at high densities leading to efficient cooling and fragmentation. The only
obvious way that molecular cooling could be avoided in the absence of strong UV
radiation, is for gas to reach high enough density to cause collisional dissociation
of molecular hydrogen (∼10^4 cm^−3) before cooling occurs. However, we argue that
the minimum core entropy, set by the entropy of the intergalactic medium (IGM)
when it decouples from the CMB, prevents this from occurring for realistic halo
masses. This is confirmed by hydrodynamical cosmological simulations without radiative
cooling. We explain the maximum density versus halo mass in these simulations
with simple entropy arguments. The low densities found suggest that DCBH formation
indeed requires a strong UV background.
article_processing_charge: No
article_type: original
author:
- first_name: Eli
full_name: Visbal, Eli
last_name: Visbal
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Greg L.
full_name: Bryan, Greg L.
last_name: Bryan
citation:
ama: 'Visbal E, Haiman Z, Bryan GL. A no-go theorem for direct collapse black holes
without a strong ultraviolet background. Monthly Notices of the Royal Astronomical
Society: Letters. 2014;442(1):L100-L104. doi:10.1093/mnrasl/slu063'
apa: 'Visbal, E., Haiman, Z., & Bryan, G. L. (2014). A no-go theorem for direct
collapse black holes without a strong ultraviolet background. Monthly Notices
of the Royal Astronomical Society: Letters. Oxford University Press. https://doi.org/10.1093/mnrasl/slu063'
chicago: 'Visbal, Eli, Zoltán Haiman, and Greg L. Bryan. “A No-Go Theorem for Direct
Collapse Black Holes without a Strong Ultraviolet Background.” Monthly Notices
of the Royal Astronomical Society: Letters. Oxford University Press, 2014.
https://doi.org/10.1093/mnrasl/slu063.'
ieee: 'E. Visbal, Z. Haiman, and G. L. Bryan, “A no-go theorem for direct collapse
black holes without a strong ultraviolet background,” Monthly Notices of the
Royal Astronomical Society: Letters, vol. 442, no. 1. Oxford University Press,
pp. L100–L104, 2014.'
ista: 'Visbal E, Haiman Z, Bryan GL. 2014. A no-go theorem for direct collapse black
holes without a strong ultraviolet background. Monthly Notices of the Royal Astronomical
Society: Letters. 442(1), L100–L104.'
mla: 'Visbal, Eli, et al. “A No-Go Theorem for Direct Collapse Black Holes without
a Strong Ultraviolet Background.” Monthly Notices of the Royal Astronomical
Society: Letters, vol. 442, no. 1, Oxford University Press, 2014, pp. L100–04,
doi:10.1093/mnrasl/slu063.'
short: 'E. Visbal, Z. Haiman, G.L. Bryan, Monthly Notices of the Royal Astronomical
Society: Letters 442 (2014) L100–L104.'
date_created: 2024-09-06T07:22:36Z
date_published: 2014-06-10T00:00:00Z
date_updated: 2024-09-24T12:04:03Z
day: '10'
doi: 10.1093/mnrasl/slu063
extern: '1'
intvolume: ' 442'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/mnrasl/slu063
month: '06'
oa: 1
oa_version: Published Version
page: L100-L104
publication: 'Monthly Notices of the Royal Astronomical Society: Letters'
publication_identifier:
issn:
- 1745-3933
- 1745-3925
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A no-go theorem for direct collapse black holes without a strong ultraviolet
background
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 442
year: '2014'
...