[{"title":"Emerging qubit systems: Guest editorial","date_created":"2022-05-29T22:01:53Z","oa_version":"Published Version","publication_identifier":{"issn":["0003-6951"]},"publication_status":"published","article_processing_charge":"No","publisher":"American Institute of Physics","author":[{"last_name":"Sigillito","full_name":"Sigillito, Anthony J.","first_name":"Anthony J."},{"full_name":"Covey, Jacob P.","last_name":"Covey","first_name":"Jacob P."},{"last_name":"Fink","full_name":"Fink, Johannes M","orcid":"0000-0001-8112-028X","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87","first_name":"Johannes M"},{"full_name":"Petersson, Karl","last_name":"Petersson","first_name":"Karl"},{"last_name":"Preble","full_name":"Preble, Stefan","first_name":"Stefan"}],"volume":120,"article_type":"letter_note","department":[{"_id":"JoFi"}],"month":"05","acknowledgement":"We would like to thank all of the authors who contributed to\r\nthis Special Topic. We would also like to thank the editorial team at\r\nAPL including Jessica Trudeau, Emma Van Burns, Martin Weides,\r\nand Lesley Cohen.","oa":1,"doi":"10.1063/5.0097339","date_published":"2022-05-12T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.1063/5.0097339","open_access":"1"}],"intvolume":"       120","article_number":"190401","year":"2022","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","day":"12","citation":{"mla":"Sigillito, Anthony J., et al. “Emerging Qubit Systems: Guest Editorial.” <i>Applied Physics Letters</i>, vol. 120, no. 19, 190401, American Institute of Physics, 2022, doi:<a href=\"https://doi.org/10.1063/5.0097339\">10.1063/5.0097339</a>.","short":"A.J. Sigillito, J.P. Covey, J.M. Fink, K. Petersson, S. Preble, Applied Physics Letters 120 (2022).","ieee":"A. J. Sigillito, J. P. Covey, J. M. Fink, K. Petersson, and S. Preble, “Emerging qubit systems: Guest editorial,” <i>Applied Physics Letters</i>, vol. 120, no. 19. American Institute of Physics, 2022.","apa":"Sigillito, A. J., Covey, J. P., Fink, J. M., Petersson, K., &#38; Preble, S. (2022). Emerging qubit systems: Guest editorial. <i>Applied Physics Letters</i>. American Institute of Physics. <a href=\"https://doi.org/10.1063/5.0097339\">https://doi.org/10.1063/5.0097339</a>","ama":"Sigillito AJ, Covey JP, Fink JM, Petersson K, Preble S. Emerging qubit systems: Guest editorial. <i>Applied Physics Letters</i>. 2022;120(19). doi:<a href=\"https://doi.org/10.1063/5.0097339\">10.1063/5.0097339</a>","ista":"Sigillito AJ, Covey JP, Fink JM, Petersson K, Preble S. 2022. Emerging qubit systems: Guest editorial. Applied Physics Letters. 120(19), 190401.","chicago":"Sigillito, Anthony J., Jacob P. Covey, Johannes M Fink, Karl Petersson, and Stefan Preble. “Emerging Qubit Systems: Guest Editorial.” <i>Applied Physics Letters</i>. American Institute of Physics, 2022. <a href=\"https://doi.org/10.1063/5.0097339\">https://doi.org/10.1063/5.0097339</a>."},"_id":"11417","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Over the past few years, the field of quantum information science has seen tremendous progress toward realizing large-scale quantum computers. With demonstrations of quantum computers outperforming classical computers for a select range of problems,1–3 we have finally entered the noisy, intermediate-scale quantum (NISQ) computing era. While the quantum computers of today are technological marvels, they are not yet error corrected, and it is unclear whether any system will scale beyond a few hundred logical qubits without significant changes to architecture and control schemes. Today's quantum systems are analogous to the ENIAC (Electronic Numerical Integrator And Computer) and EDVAC (Electronic Discrete Variable Automatic Computer) systems of the 1940s, which ran on vacuum tubes. These machines were built on a solid, nominally scalable architecture and when they were developed, nobody could have predicted the development of the transistor and the impact of the resulting semiconductor industry. Simply put, the computers of today are nothing like the early computers of the 1940s. We believe that the qubits of future fault-tolerant quantum systems will look quite different from the qubits of the NISQ machines in operation today. This Special Topic issue is devoted to new and emerging quantum systems with a focus on enabling technologies that can eventually lead to the quantum analog to the transistor. We have solicited both research4–18 and perspective articles19–21 to discuss new and emerging qubit systems with a focus on novel materials, encodings, and architectures. We are proud to present a collection that touches on a wide range of technologies including superconductors,7–13,21 semiconductors,15–17,19 and individual atomic qubits.18\r\n"}],"external_id":{"isi":["000796002100002"]},"type":"journal_article","quality_controlled":"1","issue":"19","scopus_import":"1","status":"public","date_updated":"2023-08-03T07:16:20Z","publication":"Applied Physics Letters","isi":1},{"page":"66:1-66:9","status":"public","editor":[{"first_name":"Xavier","last_name":"Goaoc","full_name":"Goaoc, Xavier"},{"first_name":"Michael","last_name":"Kerber","full_name":"Kerber, Michael"}],"scopus_import":"1","ec_funded":1,"file_date_updated":"2022-06-07T07:58:30Z","publication":"38th International Symposium on Computational Geometry","date_updated":"2025-04-14T07:43:57Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","ddc":["510"],"year":"2022","intvolume":"       224","date_published":"2022-06-01T00:00:00Z","quality_controlled":"1","type":"conference","abstract":[{"text":"The medial axis of a set consists of the points in the ambient space without a unique closest point on the original set. Since its introduction, the medial axis has been used extensively in many applications as a method of computing a topologically equivalent skeleton. Unfortunately, one limiting factor in the use of the medial axis of a smooth manifold is that it is not necessarily topologically stable under small perturbations of the manifold. To counter these instabilities various prunings of the medial axis have been proposed. Here, we examine one type of pruning, called burning. Because of the good experimental results, it was hoped that the burning method of simplifying the medial axis would be stable. In this work we show a simple example that dashes such hopes based on Bing’s house with two rooms, demonstrating an isotopy of a shape where the medial axis goes from collapsible to non-collapsible.","lang":"eng"}],"_id":"11428","language":[{"iso":"eng"}],"citation":{"ama":"Chambers E, Fillmore CD, Stephenson ER, Wintraecken M. A cautionary tale: Burning the medial axis is unstable. In: Goaoc X, Kerber M, eds. <i>38th International Symposium on Computational Geometry</i>. Vol 224. LIPIcs. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2022:66:1-66:9. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2022.66\">10.4230/LIPIcs.SoCG.2022.66</a>","ista":"Chambers E, Fillmore CD, Stephenson ER, Wintraecken M. 2022. A cautionary tale: Burning the medial axis is unstable. 38th International Symposium on Computational Geometry. SoCG: Symposium on Computational GeometryLIPIcs vol. 224, 66:1-66:9.","chicago":"Chambers, Erin, Christopher D Fillmore, Elizabeth R Stephenson, and Mathijs Wintraecken. “A Cautionary Tale: Burning the Medial Axis Is Unstable.” In <i>38th International Symposium on Computational Geometry</i>, edited by Xavier Goaoc and Michael Kerber, 224:66:1-66:9. LIPIcs. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2022.66\">https://doi.org/10.4230/LIPIcs.SoCG.2022.66</a>.","mla":"Chambers, Erin, et al. “A Cautionary Tale: Burning the Medial Axis Is Unstable.” <i>38th International Symposium on Computational Geometry</i>, edited by Xavier Goaoc and Michael Kerber, vol. 224, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022, p. 66:1-66:9, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2022.66\">10.4230/LIPIcs.SoCG.2022.66</a>.","short":"E. Chambers, C.D. Fillmore, E.R. Stephenson, M. Wintraecken, in:, X. Goaoc, M. Kerber (Eds.), 38th International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022, p. 66:1-66:9.","ieee":"E. Chambers, C. D. Fillmore, E. R. Stephenson, and M. Wintraecken, “A cautionary tale: Burning the medial axis is unstable,” in <i>38th International Symposium on Computational Geometry</i>, Berlin, Germany, 2022, vol. 224, p. 66:1-66:9.","apa":"Chambers, E., Fillmore, C. D., Stephenson, E. R., &#38; Wintraecken, M. (2022). A cautionary tale: Burning the medial axis is unstable. In X. Goaoc &#38; M. Kerber (Eds.), <i>38th International Symposium on Computational Geometry</i> (Vol. 224, p. 66:1-66:9). Berlin, Germany: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2022.66\">https://doi.org/10.4230/LIPIcs.SoCG.2022.66</a>"},"day":"01","has_accepted_license":"1","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","article_processing_charge":"No","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"corr_author":"1","series_title":"LIPIcs","oa":1,"doi":"10.4230/LIPIcs.SoCG.2022.66","acknowledgement":"Partially supported by the DFG Collaborative Research Center TRR 109, “Discretization in Geometry and Dynamics” and the European Research Council (ERC), grant no. 788183, “Alpha Shape Theory Extended”. Erin Chambers: Supported in part by the National Science Foundation through grants DBI-1759807, CCF-1907612, and CCF-2106672. Mathijs Wintraecken: Supported by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 754411. The Austrian science fund (FWF) M-3073 Acknowledgements We thank André Lieutier, David Letscher, Ellen Gasparovic, Kathryn Leonard, and Tao Ju for early discussions on this work. We also thank Lu Liu, Yajie Yan and Tao Ju for sharing code to generate the examples.","department":[{"_id":"HeEd"}],"month":"06","project":[{"name":"Learning and triangulating manifolds via collapses","grant_number":"M03073","_id":"fc390959-9c52-11eb-aca3-afa58bd282b2"},{"grant_number":"788183","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Alpha Shape Theory Extended"},{"name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411"}],"author":[{"full_name":"Chambers, Erin","last_name":"Chambers","first_name":"Erin"},{"first_name":"Christopher D","id":"35638A5C-AAC7-11E9-B0BF-5503E6697425","full_name":"Fillmore, Christopher D","last_name":"Fillmore"},{"first_name":"Elizabeth R","id":"2D04F932-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6862-208X","full_name":"Stephenson, Elizabeth R","last_name":"Stephenson"},{"last_name":"Wintraecken","full_name":"Wintraecken, Mathijs","orcid":"0000-0002-7472-2220","first_name":"Mathijs","id":"307CFBC8-F248-11E8-B48F-1D18A9856A87"}],"volume":224,"publication_identifier":{"issn":["1868-8969"],"isbn":["978-3-95977-227-3"]},"oa_version":"Published Version","title":"A cautionary tale: Burning the medial axis is unstable","date_created":"2022-06-01T14:18:04Z","publication_status":"published","conference":{"location":"Berlin, Germany","end_date":"2022-06-10","start_date":"2022-06-07","name":"SoCG: Symposium on Computational Geometry"},"file":[{"access_level":"open_access","success":1,"content_type":"application/pdf","date_created":"2022-06-07T07:58:30Z","file_size":17580705,"checksum":"b25ce40fade4ebc0bcaae176db4f5f1f","file_name":"2022_LIPICs_Chambers.pdf","file_id":"11437","date_updated":"2022-06-07T07:58:30Z","creator":"dernst","relation":"main_file"}]},{"intvolume":"     13238","place":"Cham","year":"2022","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783031062445"],"eisbn":["9783031062452"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2022-05-01T00:00:00Z","title":"Web and Wireless Geographical Information Systems","date_created":"2022-06-02T05:40:53Z","alternative_title":["LNCS"],"oa_version":"None","_id":"11429","abstract":[{"lang":"eng","text":"This book constitutes the refereed proceedings of the 18th International Symposium on Web and Wireless Geographical Information Systems, W2GIS 2022, held in Konstanz, Germany, in April 2022.\r\nThe 7 full papers presented together with 6 short papers in the volume were carefully reviewed and selected from 16 submissions.  The papers cover topics that range from mobile GIS and Location-Based Services to Spatial Information Retrieval and Wireless Sensor Networks."}],"edition":"1","language":[{"iso":"eng"}],"type":"book_editor","quality_controlled":"1","publication_status":"published","citation":{"chicago":"Karimipour, Farid, and Sabine Storandt, eds. <i>Web and Wireless Geographical Information Systems</i>. 1st ed. Vol. 13238. Cham: Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-06245-2\">https://doi.org/10.1007/978-3-031-06245-2</a>.","ista":"Karimipour F, Storandt S eds. 2022. Web and Wireless Geographical Information Systems 1st ed., Cham: Springer Nature, 153p.","ama":"Karimipour F, Storandt S, eds. <i>Web and Wireless Geographical Information Systems</i>. Vol 13238. 1st ed. Cham: Springer Nature; 2022. doi:<a href=\"https://doi.org/10.1007/978-3-031-06245-2\">10.1007/978-3-031-06245-2</a>","apa":"Karimipour, F., &#38; Storandt, S. (Eds.). (2022). <i>Web and Wireless Geographical Information Systems</i> (1st ed., Vol. 13238). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-06245-2\">https://doi.org/10.1007/978-3-031-06245-2</a>","ieee":"F. Karimipour and S. Storandt, Eds., <i>Web and Wireless Geographical Information Systems</i>, 1st ed., vol. 13238. Cham: Springer Nature, 2022.","short":"F. Karimipour, S. Storandt, eds., Web and Wireless Geographical Information Systems, 1st ed., Springer Nature, Cham, 2022.","mla":"Karimipour, Farid, and Sabine Storandt, editors. <i>Web and Wireless Geographical Information Systems</i>. 1st ed., vol. 13238, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/978-3-031-06245-2\">10.1007/978-3-031-06245-2</a>."},"day":"01","corr_author":"1","article_processing_charge":"No","publisher":"Springer Nature","page":"153","status":"public","editor":[{"id":"2A2BCDC4-CF62-11E9-BE5E-3B1EE6697425","first_name":"Farid","orcid":"0000-0001-6746-4174","full_name":"Karimipour, Farid","last_name":"Karimipour"},{"last_name":"Storandt","full_name":"Storandt, Sabine","first_name":"Sabine"}],"doi":"10.1007/978-3-031-06245-2","date_updated":"2024-10-09T21:02:30Z","volume":13238,"month":"05","department":[{"_id":"HeEd"}]},{"month":"04","department":[{"_id":"UlWa"}],"article_type":"original","volume":36,"author":[{"last_name":"Ivanov","full_name":"Ivanov, Grigory","first_name":"Grigory","id":"87744F66-5C6F-11EA-AFE0-D16B3DDC885E"},{"full_name":"Naszodi, Marton","last_name":"Naszodi","first_name":"Marton"}],"oa":1,"doi":"10.1137/21M1403308","acknowledgement":"G.I. acknowledges the financial support from the Ministry of Educational and Science of the Russian Federation in the framework of MegaGrant no 075-15-2019-1926. M.N. was supported by the National Research, Development and Innovation Fund (NRDI) grants K119670 and\r\nKKP-133864 as well as the Bolyai Scholarship of the Hungarian Academy of Sciences and the New National Excellence Programme and the TKP2020-NKA-06 program provided by the NRDI.","publisher":"Society for Industrial and Applied Mathematics","article_processing_charge":"No","publication_status":"published","oa_version":"Preprint","title":"A quantitative Helly-type theorem: Containment in a homothet","date_created":"2022-06-05T22:01:50Z","publication_identifier":{"issn":["0895-4801"]},"arxiv":1,"isi":1,"publication":"SIAM Journal on Discrete Mathematics","date_updated":"2023-10-18T06:58:03Z","scopus_import":"1","issue":"2","page":"951-957","status":"public","citation":{"apa":"Ivanov, G., &#38; Naszodi, M. (2022). A quantitative Helly-type theorem: Containment in a homothet. <i>SIAM Journal on Discrete Mathematics</i>. Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/21M1403308\">https://doi.org/10.1137/21M1403308</a>","mla":"Ivanov, Grigory, and Marton Naszodi. “A Quantitative Helly-Type Theorem: Containment in a Homothet.” <i>SIAM Journal on Discrete Mathematics</i>, vol. 36, no. 2, Society for Industrial and Applied Mathematics, 2022, pp. 951–57, doi:<a href=\"https://doi.org/10.1137/21M1403308\">10.1137/21M1403308</a>.","ieee":"G. Ivanov and M. Naszodi, “A quantitative Helly-type theorem: Containment in a homothet,” <i>SIAM Journal on Discrete Mathematics</i>, vol. 36, no. 2. Society for Industrial and Applied Mathematics, pp. 951–957, 2022.","short":"G. Ivanov, M. Naszodi, SIAM Journal on Discrete Mathematics 36 (2022) 951–957.","chicago":"Ivanov, Grigory, and Marton Naszodi. “A Quantitative Helly-Type Theorem: Containment in a Homothet.” <i>SIAM Journal on Discrete Mathematics</i>. Society for Industrial and Applied Mathematics, 2022. <a href=\"https://doi.org/10.1137/21M1403308\">https://doi.org/10.1137/21M1403308</a>.","ama":"Ivanov G, Naszodi M. A quantitative Helly-type theorem: Containment in a homothet. <i>SIAM Journal on Discrete Mathematics</i>. 2022;36(2):951-957. doi:<a href=\"https://doi.org/10.1137/21M1403308\">10.1137/21M1403308</a>","ista":"Ivanov G, Naszodi M. 2022. A quantitative Helly-type theorem: Containment in a homothet. SIAM Journal on Discrete Mathematics. 36(2), 951–957."},"day":"11","quality_controlled":"1","type":"journal_article","external_id":{"arxiv":["2103.04122"],"isi":["000793158200002"]},"abstract":[{"lang":"eng","text":"We introduce a new variant of quantitative Helly-type theorems: the minimal homothetic distance of the intersection of a family of convex sets to the intersection of a subfamily of a fixed size. As an application, we establish the following quantitative Helly-type result for the diameter. If $K$ is the intersection of finitely many convex bodies in $\\mathbb{R}^d$, then one can select $2d$ of these bodies whose intersection is of diameter at most $(2d)^3{diam}(K)$. The best previously known estimate, due to Brazitikos [Bull. Hellenic Math. Soc., 62 (2018), pp. 19--25], is $c d^{11/2}$. Moreover, we confirm that the multiplicative factor $c d^{1/2}$ conjectured by Bárány, Katchalski, and Pach [Proc. Amer. Math. Soc., 86 (1982), pp. 109--114] cannot be improved. The bounds above follow from our key result that concerns sparse approximation of a convex polytope by the convex hull of a well-chosen subset of its vertices: Assume that $Q \\subset {\\mathbb R}^d$ is a polytope whose centroid is the origin. Then there exist at most 2d vertices of $Q$ whose convex hull $Q^{\\prime \\prime}$ satisfies $Q \\subset - 8d^3 Q^{\\prime \\prime}.$"}],"_id":"11435","language":[{"iso":"eng"}],"main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2103.04122"}],"date_published":"2022-04-11T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2022","intvolume":"        36"},{"issue":"31","status":"public","date_updated":"2026-02-20T07:04:18Z","publication":"Chemistry – A European Journal","main_file_link":[{"url":"https://doi.org/10.1002/chem.202200538","open_access":"1"}],"OA_place":"publisher","date_published":"2022-06-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["540"],"year":"2022","intvolume":"        28","article_number":"e202200538","day":"01","citation":{"chicago":"Bindl, Daniel, Pradeep K Mandal, and Ivan Huc. “Generalizing the Aromatic Δ‐amino Acid Foldamer Helix.” <i>Chemistry – A European Journal</i>. Wiley, 2022. <a href=\"https://doi.org/10.1002/chem.202200538\">https://doi.org/10.1002/chem.202200538</a>.","ama":"Bindl D, Mandal PK, Huc I. Generalizing the aromatic δ‐amino acid foldamer helix. <i>Chemistry – A European Journal</i>. 2022;28(31). doi:<a href=\"https://doi.org/10.1002/chem.202200538\">10.1002/chem.202200538</a>","ista":"Bindl D, Mandal PK, Huc I. 2022. Generalizing the aromatic δ‐amino acid foldamer helix. Chemistry – A European Journal. 28(31), e202200538.","apa":"Bindl, D., Mandal, P. K., &#38; Huc, I. (2022). Generalizing the aromatic δ‐amino acid foldamer helix. <i>Chemistry – A European Journal</i>. Wiley. <a href=\"https://doi.org/10.1002/chem.202200538\">https://doi.org/10.1002/chem.202200538</a>","mla":"Bindl, Daniel, et al. “Generalizing the Aromatic Δ‐amino Acid Foldamer Helix.” <i>Chemistry – A European Journal</i>, vol. 28, no. 31, e202200538, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/chem.202200538\">10.1002/chem.202200538</a>.","short":"D. Bindl, P.K. Mandal, I. Huc, Chemistry – A European Journal 28 (2022).","ieee":"D. Bindl, P. K. Mandal, and I. Huc, “Generalizing the aromatic δ‐amino acid foldamer helix,” <i>Chemistry – A European Journal</i>, vol. 28, no. 31. Wiley, 2022."},"has_accepted_license":"1","quality_controlled":"1","type":"journal_article","external_id":{"pmid":["35332956"]},"language":[{"iso":"eng"}],"_id":"21079","abstract":[{"text":"<jats:title>Abstract</jats:title><jats:p>A series of aromatic oligoamide foldamer sequences containing different proportions of three δ‐amino acids derived from quinoline, pyridine, and benzene and possessing varying flexibility, for example due to methylene bridges, were synthesized. Crystallographic structures of two key sequences and <jats:sup>1</jats:sup>H NMR data in water concur to show that a canonical aromatic helix fold prevails in almost all cases and that helix stability critically depends on the ratio between rigid and flexible units. Notwithstanding subtle variations of curvature, i. e. the numbers of units per turn, the aromatic δ‐peptide helix is therefore shown to be general and tolerant of a great number of sp<jats:sup>3</jats:sup> centers. We also demonstrate canonical helical folding upon alternating two monomers that do not promote folding when taken separately: folding occurs with two methylenes between every other unit, not with one methylene between every unit. These findings highlight that a fine‐tuning of helix handedness inversion kinetics, curvature, and side chain positioning in aromatic δ‐peptidic foldamers can be realized by systematically combining different yet compatible δ‐amino acids.</jats:p>","lang":"eng"}],"pmid":1,"extern":"1","publisher":"Wiley","article_processing_charge":"No","tmp":{"image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode"},"month":"06","article_type":"original","author":[{"first_name":"Daniel","last_name":"Bindl","full_name":"Bindl, Daniel"},{"last_name":"Mandal","full_name":"Mandal, Pradeep K","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","first_name":"Pradeep K"},{"last_name":"Huc","full_name":"Huc, Ivan","first_name":"Ivan"}],"volume":28,"oa":1,"doi":"10.1002/chem.202200538","OA_type":"hybrid","oa_version":"Published Version","date_created":"2026-01-29T15:05:40Z","title":"Generalizing the aromatic δ‐amino acid foldamer helix","publication_identifier":{"eissn":["1521-3765"],"issn":["0947-6539"]},"publication_status":"published"},{"publisher":"Public Library of Science","article_processing_charge":"Yes","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"pmid":1,"oa":1,"doi":"10.1371/journal.pbio.3001786","acknowledgement":"We thank members of the Conradt, Lambie, and Hajnal labs for discussions and comments on the manuscript. We thank M. Bauer, L. Jocham, N. Lebedeva, and L. McGuinness for excellent technical support; A. Hajnal and T. Kohlbrenner (University of Zurich, Switzerland) for allele zh135; and H.R. Horvitz (Massachusetts of Technology, USA) for plasmid pET-CED-3.\r\nSome strains were provided by the Caenorhabditis Genetics Center (CGC), which is funded by NIH Office of Research Infrastructure Programs (https://orip.nih.gov/) (P40 OD010440). This work was supported by UCL (Capital Equipment Fund, CEF2), a predoctoral fellowship from the China Scholarship Council (https://www.csc.edu.cn/) to HW, a predoctoral fellowship from the Studienstiftung des Deutschen Volkes (https://www.studienstiftung.de/) to NM, a Wolfson Fellowship from the Royal Society (https://royalsociety.org/) to BC (RSWF\\R1\\180008), the Deutsche Forschungsgemeinschaft (https://www.dfg.de/en/index.jsp) (ZA619/3-1 and ZA619/3-2 to EZ; C0204/10-1 and EXC114 to BC), and the Biotechnology and Biological Sciences Research Council (https://bbsrc.ukri.org/) (BB/V007572/1 to BC). ","month":"10","department":[{"_id":"CaHe"}],"article_type":"original","author":[{"first_name":"Aditya","full_name":"Sethi, Aditya","last_name":"Sethi"},{"first_name":"Hai","last_name":"Wei","full_name":"Wei, Hai"},{"first_name":"Nikhil","id":"C4D70E82-1081-11EA-B3ED-9A4C3DDC885E","orcid":"0000-0002-6425-5788","last_name":"Mishra","full_name":"Mishra, Nikhil"},{"full_name":"Segos, Ioannis","last_name":"Segos","first_name":"Ioannis"},{"last_name":"Lambie","full_name":"Lambie, Eric J.","first_name":"Eric J."},{"last_name":"Zanin","full_name":"Zanin, Esther","first_name":"Esther"},{"last_name":"Conradt","full_name":"Conradt, Barbara","first_name":"Barbara"}],"volume":20,"publication_identifier":{"issn":["1545-7885"]},"oa_version":"Published Version","title":"A caspase–RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans","date_created":"2024-05-29T06:09:34Z","publication_status":"published","file":[{"file_size":2515388,"date_created":"2024-08-06T07:07:52Z","success":1,"content_type":"application/pdf","access_level":"open_access","file_id":"17399","date_updated":"2024-08-06T07:07:52Z","creator":"dernst","relation":"main_file","file_name":"2022_PlosBio_Sethi.pdf","checksum":"a7b46460b7819c196028481cc18a7c85"}],"status":"public","scopus_import":"1","issue":"10","file_date_updated":"2024-08-06T07:07:52Z","publication":"PLOS Biology","date_updated":"2024-08-06T07:08:54Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"year":"2022","intvolume":"        20","article_number":"e3001786","date_published":"2022-10-06T00:00:00Z","quality_controlled":"1","type":"journal_article","external_id":{"pmid":["36201522"]},"_id":"17066","abstract":[{"text":"A cell’s size affects the likelihood that it will die. But how is cell size controlled in this context and how does cell size impact commitment to the cell death fate? We present evidence that the caspase CED-3 interacts with the RhoGEF ECT-2 in Caenorhabditis elegans neuroblasts that generate “unwanted” cells. We propose that this interaction promotes polar actomyosin contractility, which leads to unequal neuroblast division and the generation of a daughter cell that is below the critical “lethal” size threshold. Furthermore, we find that hyperactivation of ECT-2 RhoGEF reduces the sizes of unwanted cells. Importantly, this suppresses the “cell death abnormal” phenotype caused by the partial loss of ced-3 caspase and therefore increases the likelihood that unwanted cells die. A putative null mutation of ced-3 caspase, however, is not suppressed, which indicates that cell size affects CED-3 caspase activation and/or activity. Therefore, we have uncovered novel sequential and reciprocal interactions between the apoptosis pathway and cell size that impact a cell’s commitment to the cell death fate.","lang":"eng"}],"language":[{"iso":"eng"}],"citation":{"apa":"Sethi, A., Wei, H., Mishra, N., Segos, I., Lambie, E. J., Zanin, E., &#38; Conradt, B. (2022). A caspase–RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans. <i>PLOS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.3001786\">https://doi.org/10.1371/journal.pbio.3001786</a>","mla":"Sethi, Aditya, et al. “A Caspase–RhoGEF Axis Contributes to the Cell Size Threshold for Apoptotic Death in Developing Caenorhabditis Elegans.” <i>PLOS Biology</i>, vol. 20, no. 10, e3001786, Public Library of Science, 2022, doi:<a href=\"https://doi.org/10.1371/journal.pbio.3001786\">10.1371/journal.pbio.3001786</a>.","ieee":"A. Sethi <i>et al.</i>, “A caspase–RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans,” <i>PLOS Biology</i>, vol. 20, no. 10. Public Library of Science, 2022.","short":"A. Sethi, H. Wei, N. Mishra, I. Segos, E.J. Lambie, E. Zanin, B. Conradt, PLOS Biology 20 (2022).","chicago":"Sethi, Aditya, Hai Wei, Nikhil Mishra, Ioannis Segos, Eric J. Lambie, Esther Zanin, and Barbara Conradt. “A Caspase–RhoGEF Axis Contributes to the Cell Size Threshold for Apoptotic Death in Developing Caenorhabditis Elegans.” <i>PLOS Biology</i>. Public Library of Science, 2022. <a href=\"https://doi.org/10.1371/journal.pbio.3001786\">https://doi.org/10.1371/journal.pbio.3001786</a>.","ama":"Sethi A, Wei H, Mishra N, et al. A caspase–RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans. <i>PLOS Biology</i>. 2022;20(10). doi:<a href=\"https://doi.org/10.1371/journal.pbio.3001786\">10.1371/journal.pbio.3001786</a>","ista":"Sethi A, Wei H, Mishra N, Segos I, Lambie EJ, Zanin E, Conradt B. 2022. A caspase–RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans. PLOS Biology. 20(10), e3001786."},"day":"06","has_accepted_license":"1"},{"scopus_import":"1","editor":[{"full_name":"Blau, Nenad","last_name":"Blau","first_name":"Nenad"},{"last_name":"Vici","full_name":"Vici, Carlo Dionisi","first_name":"Carlo Dionisi"},{"first_name":"Carlos R. ","full_name":"Ferreira, Carlos R. ","last_name":"Ferreira"},{"first_name":"Christine","full_name":"Vianey-Saban, Christine","last_name":"Vianey-Saban"},{"last_name":"van Karnebeek","full_name":"van Karnebeek, Clara D.M.","first_name":"Clara D.M."}],"article_processing_charge":"No","publisher":"Springer Nature","page":"291-312","status":"public","publication":"Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases","date_updated":"2024-07-31T11:45:50Z","author":[{"last_name":"Palacín","full_name":"Palacín, Manuel","first_name":"Manuel"},{"full_name":"Bröer, Stefan","last_name":"Bröer","first_name":"Stefan"},{"full_name":"Novarino, Gaia","last_name":"Novarino","first_name":"Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7673-7178"}],"month":"02","department":[{"_id":"GaNo"}],"acknowledgement":"The authors thank Dr. Christian Lueck (Canberra Hospital) for clarification of differential diagnosis in cases of episodic ataxia. The authors thank Dr. Rafael Artuch (Hospital San Joan de Deu, Barcelona) for reference values of plasma amino acid concentration. The authors also thank Lisa Kraus (Institute of Science and Technology-Austria) and Dr. Susanna Bodoy (IRB-Barcelona) that helped in preparing tables and bibliography.","doi":"10.1007/978-3-030-67727-5_18","date_published":"2022-02-22T00:00:00Z","title":"Amino Acid Transport Defects","date_created":"2024-05-29T06:13:04Z","oa_version":"None","place":"Cham","publication_identifier":{"eisbn":["9783030677275"],"isbn":["9783030677268"]},"year":"2022","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"22","citation":{"ama":"Palacín M, Bröer S, Novarino G. Amino Acid Transport Defects. In: Blau N, Vici CD, Ferreira CR, Vianey-Saban C, van Karnebeek CDM, eds. <i>Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases</i>. 2nd ed. Cham: Springer Nature; 2022:291-312. doi:<a href=\"https://doi.org/10.1007/978-3-030-67727-5_18\">10.1007/978-3-030-67727-5_18</a>","ista":"Palacín M, Bröer S, Novarino G. 2022.Amino Acid Transport Defects. In: Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases. , 291–312.","chicago":"Palacín, Manuel, Stefan Bröer, and Gaia Novarino. “Amino Acid Transport Defects.” In <i>Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases</i>, edited by Nenad Blau, Carlo Dionisi Vici, Carlos R.  Ferreira, Christine Vianey-Saban, and Clara D.M. van Karnebeek, 2nd ed., 291–312. Cham: Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-030-67727-5_18\">https://doi.org/10.1007/978-3-030-67727-5_18</a>.","mla":"Palacín, Manuel, et al. “Amino Acid Transport Defects.” <i>Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases</i>, edited by Nenad Blau et al., 2nd ed., Springer Nature, 2022, pp. 291–312, doi:<a href=\"https://doi.org/10.1007/978-3-030-67727-5_18\">10.1007/978-3-030-67727-5_18</a>.","short":"M. Palacín, S. Bröer, G. Novarino, in:, N. Blau, C.D. Vici, C.R. Ferreira, C. Vianey-Saban, C.D.M. van Karnebeek (Eds.), Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases, 2nd ed., Springer Nature, Cham, 2022, pp. 291–312.","ieee":"M. Palacín, S. Bröer, and G. Novarino, “Amino Acid Transport Defects,” in <i>Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases</i>, 2nd ed., N. Blau, C. D. Vici, C. R. Ferreira, C. Vianey-Saban, and C. D. M. van Karnebeek, Eds. Cham: Springer Nature, 2022, pp. 291–312.","apa":"Palacín, M., Bröer, S., &#38; Novarino, G. (2022). Amino Acid Transport Defects. In N. Blau, C. D. Vici, C. R. Ferreira, C. Vianey-Saban, &#38; C. D. M. van Karnebeek (Eds.), <i>Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases</i> (2nd ed., pp. 291–312). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-67727-5_18\">https://doi.org/10.1007/978-3-030-67727-5_18</a>"},"_id":"17075","edition":"2","abstract":[{"text":"Disorders associated with the malfunction of amino acid transporters mainly affect the function of the intestine, kidney, brain, and liver. Mutations of brain amino acid transporters, for example, alter neuronal excitability (e.g., episodic ataxia due to SLC1A3 (EAAT1) defect and hyperekplexia due to SLC6A5 (GLYT2) deficiency) or brain development (SLC1A1 (EAAT3), SLC3A2/SLC7A5 (CD98hc/LAT1), and SLC1A4 (ASCT1) deficiencies). Mutations of renal and intestinal amino acid transporters SLC3A1/SLC7A9 (rBAT/b0,+AT) and SLC1A1 (EAAT3) cause renal problems (cystinuria and dicarboxylic aminoaciduria, respectively) and malabsorption that can affect whole-body homoeostasis (Hartnup disorder SLC6A19 (B0AT1), lysinuric protein intolerance SLC3A2/SLC7A7 (CD98hc/y+LAT1), and hyperdibasic aminoaciduria type 1). Mutations in the neuronal system A amino acid transporter SLC38A8 (SNAT8) cause eye developmental and visual defects. Inborn errors associated with mitochondrial SLC25 family members such as SLC25A12 (neuronal- and muscle-specific mitochondrial aspartate/glutamate transporter 1; AGC1) (global cerebral hypomyelination), SLC25A13 (aspartate/glutamate transporter 2) (citrin deficiency), SLC25A15 (ornithine-citrulline carrier 2) (homocitrullinuria, hyperornithinemia, and hyperammonemia syndrome), and SLC25A22 (mitochondrial glutamate/H+ symporter 1, GC1) (neonatal myoclonic epilepsy) will be dealt within Chap. 43 (defects of mitochondrial carriers).","lang":"eng"}],"language":[{"iso":"eng"}],"type":"book_chapter","quality_controlled":"1","publication_status":"published"},{"citation":{"ieee":"R. E. O’Brien, J. P. K. Bravo, D. Ramos, G. N. Hibshman, J. T. Wright, and D. W. Taylor, “Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory, 2022.","short":"R.E. O’Brien, J.P.K. Bravo, D. Ramos, G.N. Hibshman, J.T. Wright, D.W. Taylor, BioRxiv (2022).","mla":"O’Brien, Roisin E., et al. “Modes of Inhibition Used by Phage Anti-CRISPRs to Evade Type I-C Cascade.” <i>BioRxiv</i>, Cold Spring Harbor Laboratory, 2022, doi:<a href=\"https://doi.org/10.1101/2022.06.15.496202\">10.1101/2022.06.15.496202</a>.","apa":"O’Brien, R. E., Bravo, J. P. K., Ramos, D., Hibshman, G. N., Wright, J. T., &#38; Taylor, D. W. (2022). Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade. <i>bioRxiv</i>. Cold Spring Harbor Laboratory. <a href=\"https://doi.org/10.1101/2022.06.15.496202\">https://doi.org/10.1101/2022.06.15.496202</a>","ista":"O’Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. 2022. Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade. bioRxiv, <a href=\"https://doi.org/10.1101/2022.06.15.496202\">10.1101/2022.06.15.496202</a>.","ama":"O’Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade. <i>bioRxiv</i>. 2022. doi:<a href=\"https://doi.org/10.1101/2022.06.15.496202\">10.1101/2022.06.15.496202</a>","chicago":"O’Brien, Roisin E., Jack Peter Kelly Bravo, Delisa Ramos, Grace N. Hibshman, Jacquelyn T. Wright, and David W. Taylor. “Modes of Inhibition Used by Phage Anti-CRISPRs to Evade Type I-C Cascade.” <i>BioRxiv</i>. Cold Spring Harbor Laboratory, 2022. <a href=\"https://doi.org/10.1101/2022.06.15.496202\">https://doi.org/10.1101/2022.06.15.496202</a>."},"day":"15","type":"preprint","publication_status":"published","_id":"17115","abstract":[{"text":"Cascades are RNA-guided multi-subunit CRISPR-Cas surveillances complexes that target foreign nucleic acids for destruction. Here, we present a 2.9-Å resolution cryo-electron (cryo-EM) structure of the <jats:italic>D. vulgaris</jats:italic> type I-C Cascade bound to a double-stranded (ds)DNA target. Our data shows how the 5’-TTC-3’ protospacer adjacent motif (PAM) sequence is recognized, and provides a unique mechanism through which the displaced, single-stranded non-target strand (NTS) is stabilized via stacking interactions with protein subunits in order to favor R-loop formation and prevent dsDNA re-annealing. Additionally, we provide structural insights into how diverse anti-CRISPR (Acr) proteins utilize distinct strategies to achieve a shared mechanism of type I-C Cascade inhibition by blocking initial DNA binding. These observations provide a structural basis for directional R-loop formation and reveal how divergent Acr proteins have converged upon common molecular mechanisms to efficiently shut down CRISPR immunity.","lang":"eng"}],"language":[{"iso":"eng"}],"oa_version":"Preprint","main_file_link":[{"url":"https://doi.org/10.1101/2022.06.15.496202","open_access":"1"}],"date_published":"2022-06-15T00:00:00Z","date_created":"2024-06-04T06:43:30Z","title":"Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade","year":"2022","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"06","date_updated":"2024-06-04T07:03:02Z","publication":"bioRxiv","author":[{"full_name":"O’Brien, Roisin E.","last_name":"O’Brien","first_name":"Roisin E."},{"orcid":"0000-0003-0456-0753","first_name":"Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","full_name":"Bravo, Jack Peter Kelly","last_name":"Bravo"},{"last_name":"Ramos","full_name":"Ramos, Delisa","first_name":"Delisa"},{"full_name":"Hibshman, Grace N.","last_name":"Hibshman","first_name":"Grace N."},{"full_name":"Wright, Jacquelyn T.","last_name":"Wright","first_name":"Jacquelyn T."},{"full_name":"Taylor, David W.","last_name":"Taylor","first_name":"David W."}],"oa":1,"doi":"10.1101/2022.06.15.496202","extern":"1","publisher":"Cold Spring Harbor Laboratory","status":"public","article_processing_charge":"No"},{"publication_status":"published","title":"How binaries accrete: Hydrodynamic simulations with passive tracer particles","date_created":"2024-09-05T10:17:13Z","oa_version":"Published Version","publication_identifier":{"issn":["0004-637X","1538-4357"]},"volume":932,"author":[{"first_name":"Christopher","full_name":"Tiede, Christopher","last_name":"Tiede"},{"last_name":"Zrake","full_name":"Zrake, Jonathan","first_name":"Jonathan"},{"last_name":"MacFadyen","full_name":"MacFadyen, Andrew","first_name":"Andrew"},{"full_name":"Haiman, Zoltán","last_name":"Haiman","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán"}],"article_type":"original","month":"06","doi":"10.3847/1538-4357/ac6c2b","oa":1,"extern":"1","article_processing_charge":"No","publisher":"American Astronomical Society","citation":{"chicago":"Tiede, Christopher, Jonathan Zrake, Andrew MacFadyen, and Zoltán Haiman. “How Binaries Accrete: Hydrodynamic Simulations with Passive Tracer Particles.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2022. <a href=\"https://doi.org/10.3847/1538-4357/ac6c2b\">https://doi.org/10.3847/1538-4357/ac6c2b</a>.","ista":"Tiede C, Zrake J, MacFadyen A, Haiman Z. 2022. How binaries accrete: Hydrodynamic simulations with passive tracer particles. The Astrophysical Journal. 932(1), 24.","ama":"Tiede C, Zrake J, MacFadyen A, Haiman Z. How binaries accrete: Hydrodynamic simulations with passive tracer particles. <i>The Astrophysical Journal</i>. 2022;932(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ac6c2b\">10.3847/1538-4357/ac6c2b</a>","apa":"Tiede, C., Zrake, J., MacFadyen, A., &#38; Haiman, Z. (2022). How binaries accrete: Hydrodynamic simulations with passive tracer particles. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/ac6c2b\">https://doi.org/10.3847/1538-4357/ac6c2b</a>","ieee":"C. Tiede, J. Zrake, A. MacFadyen, and Z. Haiman, “How binaries accrete: Hydrodynamic simulations with passive tracer particles,” <i>The Astrophysical Journal</i>, vol. 932, no. 1. American Astronomical Society, 2022.","short":"C. Tiede, J. Zrake, A. MacFadyen, Z. Haiman, The Astrophysical Journal 932 (2022).","mla":"Tiede, Christopher, et al. “How Binaries Accrete: Hydrodynamic Simulations with Passive Tracer Particles.” <i>The Astrophysical Journal</i>, vol. 932, no. 1, 24, American Astronomical Society, 2022, doi:<a href=\"https://doi.org/10.3847/1538-4357/ac6c2b\">10.3847/1538-4357/ac6c2b</a>."},"day":"13","_id":"17553","language":[{"iso":"eng"}],"abstract":[{"text":"Linear analysis of gas flows around orbiting binaries suggests that a centrifugal barrier ought to clear a low-density cavity around the binary and inhibit mass transfer onto it. Modern hydrodynamics simulations have confirmed the low-density cavity, but show that any mass flowing from large scales into the circumbinary disk is eventually transferred onto the binary components. Even though many numerical studies confirm this picture, it is still not understood precisely how gas parcels overcome the centrifugal barrier and ultimately accrete. We present a detailed analysis of the binary accretion process, using an accurate prescription for evolving grid-based hydrodynamics with Lagrangian tracer particles that track the trajectories of individual gas parcels. We find that binary accretion can be described in four phases: (1) gas is viscously transported through the circumbinary disk up to the centrifugal barrier at the cavity wall, (2) the cavity wall is tidally distorted into accretion streams consisting of near-ballistic gas parcels on eccentric orbits, (3) the portion of each stream moving inwards of an ``accretion horizon'' radius r¯≃a -- the radius beyond which no material is returned to the cavity wall -- becomes bound to a minidisk orbiting an individual binary component, and (4) the minidisk gas accretes onto the binary component through the combined effect of viscous and tidal stresses.","lang":"eng"}],"type":"journal_article","quality_controlled":"1","date_published":"2022-06-13T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.3847/1538-4357/ac6c2b"}],"intvolume":"       932","article_number":"24","year":"2022","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"The Astrophysical Journal","date_updated":"2024-09-18T10:18:01Z","issue":"1","scopus_import":"1","status":"public"},{"scopus_import":"1","issue":"2","status":"public","date_updated":"2024-09-18T12:38:14Z","publication":"The Astrophysical Journal Letters","main_file_link":[{"url":"https://doi.org/10.3847/2041-8213/ac7c0b","open_access":"1"}],"date_published":"2022-07-07T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2022","intvolume":"       933","article_number":"L28","citation":{"apa":"Yang, Y., Bartos, I., Fragione, G., Haiman, Z., Kowalski, M., Márka, S., … Tagawa, H. (2022). Tidal disruption on stellar-mass black holes in active galactic nuclei. <i>The Astrophysical Journal Letters</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/2041-8213/ac7c0b\">https://doi.org/10.3847/2041-8213/ac7c0b</a>","short":"Y. Yang, I. Bartos, G. Fragione, Z. Haiman, M. Kowalski, S. Márka, R. Perna, H. Tagawa, The Astrophysical Journal Letters 933 (2022).","ieee":"Y. Yang <i>et al.</i>, “Tidal disruption on stellar-mass black holes in active galactic nuclei,” <i>The Astrophysical Journal Letters</i>, vol. 933, no. 2. American Astronomical Society, 2022.","mla":"Yang, Y., et al. “Tidal Disruption on Stellar-Mass Black Holes in Active Galactic Nuclei.” <i>The Astrophysical Journal Letters</i>, vol. 933, no. 2, L28, American Astronomical Society, 2022, doi:<a href=\"https://doi.org/10.3847/2041-8213/ac7c0b\">10.3847/2041-8213/ac7c0b</a>.","chicago":"Yang, Y., I. Bartos, G. Fragione, Zoltán Haiman, M. Kowalski, S. Márka, R. Perna, and H. Tagawa. “Tidal Disruption on Stellar-Mass Black Holes in Active Galactic Nuclei.” <i>The Astrophysical Journal Letters</i>. American Astronomical Society, 2022. <a href=\"https://doi.org/10.3847/2041-8213/ac7c0b\">https://doi.org/10.3847/2041-8213/ac7c0b</a>.","ista":"Yang Y, Bartos I, Fragione G, Haiman Z, Kowalski M, Márka S, Perna R, Tagawa H. 2022. Tidal disruption on stellar-mass black holes in active galactic nuclei. The Astrophysical Journal Letters. 933(2), L28.","ama":"Yang Y, Bartos I, Fragione G, et al. Tidal disruption on stellar-mass black holes in active galactic nuclei. <i>The Astrophysical Journal Letters</i>. 2022;933(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/ac7c0b\">10.3847/2041-8213/ac7c0b</a>"},"day":"07","quality_controlled":"1","type":"journal_article","abstract":[{"lang":"eng","text":"Active galactic nuclei (AGNs) can funnel stars and stellar remnants from the vicinity of the galactic center into the inner plane of the AGN disk. Stars reaching this inner region can be tidally disrupted by the stellar-mass black holes in the disk. Such micro tidal disruption events (micro-TDEs) could be a useful probe of stellar interaction with the AGN disk. We find that micro-TDEs in AGNs occur at a rate of ∼170 Gpc−3 yr−1. Their cleanest observational probe may be the electromagnetic detection of tidal disruption in AGNs by heavy supermassive black holes (M• ≳ 108 M⊙) that cannot tidally disrupt solar-type stars. The reconstructed rate of such events from observations, nonetheless, appears to be much lower than our estimated micro-TDE rate. We discuss two such micro-TDE candidates observed to date (ASASSN-15lh and ZTF19aailpwl)."}],"_id":"17561","language":[{"iso":"eng"}],"extern":"1","publisher":"American Astronomical Society","article_processing_charge":"No","month":"07","article_type":"original","volume":933,"author":[{"full_name":"Yang, Y.","last_name":"Yang","first_name":"Y."},{"first_name":"I.","full_name":"Bartos, I.","last_name":"Bartos"},{"first_name":"G.","last_name":"Fragione","full_name":"Fragione, G."},{"last_name":"Haiman","full_name":"Haiman, Zoltán","first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36"},{"first_name":"M.","last_name":"Kowalski","full_name":"Kowalski, M."},{"last_name":"Márka","full_name":"Márka, S.","first_name":"S."},{"first_name":"R.","last_name":"Perna","full_name":"Perna, R."},{"full_name":"Tagawa, H.","last_name":"Tagawa","first_name":"H."}],"doi":"10.3847/2041-8213/ac7c0b","oa":1,"oa_version":"Published Version","title":"Tidal disruption on stellar-mass black holes in active galactic nuclei","date_created":"2024-09-05T12:01:54Z","publication_identifier":{"issn":["2041-8205","2041-8213"]},"publication_status":"published"},{"publication":"Monthly Notices of the Royal Astronomical Society","date_updated":"2024-09-19T07:18:22Z","page":"2155-2168","status":"public","scopus_import":"1","issue":"2","quality_controlled":"1","type":"journal_article","abstract":[{"text":"The existence of 109 M⊙ supermassive black holes (SMBHs) within the first billion years of the Universe remains a puzzle in our conventional understanding of black hole formation and growth. Several suggested formation pathways for these SMBHs lead to a heavy seed, with an initial black hole mass of 104–106 M⊙. This can lead to an overly massive BH galaxy (OMBG), whose nuclear black hole’s mass is comparable to or even greater than the surrounding stellar mass: the black hole to stellar mass ratio is Mbh/M* ≫ 10−3, well in excess of the typical values at lower redshift. We investigate how long these newborn BHs remain outliers in the Mbh − M* relation, by exploring the subsequent evolution of two OMBGs previously identified in the Renaissance simulations. We find that both OMBGs have Mbh/M* &amp;gt; 1 during their entire life, from their birth at z ≈ 15 until they merge with much more massive haloes at z ≈ 8. We find that the OMBGs are spatially resolvable from their more massive, 1011 M⊙, neighbouring haloes until their mergers are complete at z ≈ 8. This affords a window for future observations with JWST and sensitive X-ray telescopes to diagnose the heavy-seed scenario, by detecting similar OMBGs and establishing their uniquely high black hole-to-stellar mass ratio.","lang":"eng"}],"_id":"17571","language":[{"iso":"eng"}],"day":"20","citation":{"chicago":"Scoggins, Matthew T, Zoltán Haiman, and John H Wise. “How Long Do High Redshift Massive Black Hole Seeds Remain Outliers in Black Hole versus Host Galaxy Relations?” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2022. <a href=\"https://doi.org/10.1093/mnras/stac3715\">https://doi.org/10.1093/mnras/stac3715</a>.","ama":"Scoggins MT, Haiman Z, Wise JH. How long do high redshift massive black hole seeds remain outliers in black hole versus host galaxy relations? <i>Monthly Notices of the Royal Astronomical Society</i>. 2022;519(2):2155-2168. doi:<a href=\"https://doi.org/10.1093/mnras/stac3715\">10.1093/mnras/stac3715</a>","ista":"Scoggins MT, Haiman Z, Wise JH. 2022. How long do high redshift massive black hole seeds remain outliers in black hole versus host galaxy relations? Monthly Notices of the Royal Astronomical Society. 519(2), 2155–2168.","apa":"Scoggins, M. T., Haiman, Z., &#38; Wise, J. H. (2022). How long do high redshift massive black hole seeds remain outliers in black hole versus host galaxy relations? <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stac3715\">https://doi.org/10.1093/mnras/stac3715</a>","mla":"Scoggins, Matthew T., et al. “How Long Do High Redshift Massive Black Hole Seeds Remain Outliers in Black Hole versus Host Galaxy Relations?” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 519, no. 2, Oxford University Press, 2022, pp. 2155–68, doi:<a href=\"https://doi.org/10.1093/mnras/stac3715\">10.1093/mnras/stac3715</a>.","ieee":"M. T. Scoggins, Z. Haiman, and J. H. Wise, “How long do high redshift massive black hole seeds remain outliers in black hole versus host galaxy relations?,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 519, no. 2. Oxford University Press, pp. 2155–2168, 2022.","short":"M.T. Scoggins, Z. Haiman, J.H. Wise, Monthly Notices of the Royal Astronomical Society 519 (2022) 2155–2168."},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2022","intvolume":"       519","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/mnras/stac3715"}],"date_published":"2022-12-20T00:00:00Z","oa":1,"doi":"10.1093/mnras/stac3715","month":"12","article_type":"original","author":[{"first_name":"Matthew T","last_name":"Scoggins","full_name":"Scoggins, Matthew T"},{"first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","full_name":"Haiman, Zoltán","last_name":"Haiman"},{"first_name":"John H","full_name":"Wise, John H","last_name":"Wise"}],"volume":519,"publisher":"Oxford University Press","article_processing_charge":"No","extern":"1","publication_status":"published","publication_identifier":{"issn":["0035-8711","1365-2966"]},"oa_version":"Published Version","date_created":"2024-09-05T12:14:22Z","title":"How long do high redshift massive black hole seeds remain outliers in black hole versus host galaxy relations?"},{"doi":"10.1093/mnras/stac3664","oa":1,"volume":519,"author":[{"last_name":"De Rosa","full_name":"De Rosa, Alessandra","first_name":"Alessandra"},{"last_name":"Vignali","full_name":"Vignali, Cristian","first_name":"Cristian"},{"full_name":"Severgnini, Paola","last_name":"Severgnini","first_name":"Paola"},{"last_name":"Bianchi","full_name":"Bianchi, Stefano","first_name":"Stefano"},{"full_name":"Bogdanović, Tamara","last_name":"Bogdanović","first_name":"Tamara"},{"first_name":"Maria","last_name":"Charisi","full_name":"Charisi, Maria"},{"last_name":"Guainazzi","full_name":"Guainazzi, Matteo","first_name":"Matteo"},{"full_name":"Haiman, Zoltán","last_name":"Haiman","first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36"},{"last_name":"Komossa","full_name":"Komossa, S","first_name":"S"},{"last_name":"Paragi","full_name":"Paragi, Zsolt","first_name":"Zsolt"},{"full_name":"Perez-Torres, Miguel","last_name":"Perez-Torres","first_name":"Miguel"},{"first_name":"Enrico","last_name":"Piconcelli","full_name":"Piconcelli, Enrico"},{"first_name":"Lorenzo","full_name":"Ducci, Lorenzo","last_name":"Ducci"},{"full_name":"Parvatikar, Manali","last_name":"Parvatikar","first_name":"Manali"},{"full_name":"Serafinelli, Roberto","last_name":"Serafinelli","first_name":"Roberto"}],"month":"12","article_processing_charge":"No","publisher":"Oxford University Press","extern":"1","publication_status":"published","publication_identifier":{"issn":["0035-8711","1365-2966"]},"date_created":"2024-09-05T12:23:59Z","title":"The X-ray view of optically selected dual AGN","oa_version":"None","publication":"Monthly Notices of the Royal Astronomical Society","date_updated":"2024-09-19T11:24:50Z","page":"5149-5160","status":"public","issue":"4","scopus_import":"1","language":[{"iso":"eng"}],"_id":"17580","abstract":[{"text":"We present a study of optically selected dual Active Galactic Nuclei (AGN) with projected separations of 3–97 kpc. Using multiwavelength (MWL) information (optical, X-ray, mid-IR), we characterized the intrinsic nuclear properties of this sample and compared them with those of isolated systems. Among the 124 X-ray-detected AGN candidates, 52 appear in pairs and 72 as single X-ray sources. Through MWL analysis, we confirmed the presence of the AGN in &amp;gt;80 per cent of the detected targets in pairs (42 out of 52). X-ray spectral analysis confirms the trend of increasing AGN luminosity with decreasing separation, suggesting that mergers may have contributed to triggering more luminous AGN. Through X-ray/mid-IR ratio versus X-ray colours, we estimated a fraction of Compton-thin AGN (with 1022 cm−2 &amp;lt; NH &amp;lt; 1024 cm−2) of about 80 per cent, while about 16 per cent are Compton-thick sources (with NH &amp;gt; 1024 cm−2). These fractions of obscured sources are larger than those found in samples of isolated AGN, confirming that pairs of AGN show higher obscuration. This trend is further confirmed by comparing the de-reddened [O iii] emission with the observed X-ray luminosity. However, the derived fraction of Compton-thick sources in this sample at the early stages of merging is lower than that reported for late-merging dual-AGN samples. Comparing NH from X-rays with that derived from E(B − V) from narrow-line regions, we found that the absorbing material is likely to be associated with the torus or broad-line regions. We also explored the X-ray detection efficiency of dual-AGN candidates, finding that, when observed properly (at on-axis positions and with long exposures), X-ray data represent a powerful way to confirm and investigate dual-AGN systems.","lang":"eng"}],"quality_controlled":"1","type":"journal_article","day":"15","citation":{"ista":"De Rosa A, Vignali C, Severgnini P, Bianchi S, Bogdanović T, Charisi M, Guainazzi M, Haiman Z, Komossa S, Paragi Z, Perez-Torres M, Piconcelli E, Ducci L, Parvatikar M, Serafinelli R. 2022. The X-ray view of optically selected dual AGN. Monthly Notices of the Royal Astronomical Society. 519(4), 5149–5160.","ama":"De Rosa A, Vignali C, Severgnini P, et al. The X-ray view of optically selected dual AGN. <i>Monthly Notices of the Royal Astronomical Society</i>. 2022;519(4):5149-5160. doi:<a href=\"https://doi.org/10.1093/mnras/stac3664\">10.1093/mnras/stac3664</a>","chicago":"De Rosa, Alessandra, Cristian Vignali, Paola Severgnini, Stefano Bianchi, Tamara Bogdanović, Maria Charisi, Matteo Guainazzi, et al. “The X-Ray View of Optically Selected Dual AGN.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2022. <a href=\"https://doi.org/10.1093/mnras/stac3664\">https://doi.org/10.1093/mnras/stac3664</a>.","ieee":"A. De Rosa <i>et al.</i>, “The X-ray view of optically selected dual AGN,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 519, no. 4. Oxford University Press, pp. 5149–5160, 2022.","short":"A. De Rosa, C. Vignali, P. Severgnini, S. Bianchi, T. Bogdanović, M. Charisi, M. Guainazzi, Z. Haiman, S. Komossa, Z. Paragi, M. Perez-Torres, E. Piconcelli, L. Ducci, M. Parvatikar, R. Serafinelli, Monthly Notices of the Royal Astronomical Society 519 (2022) 5149–5160.","mla":"De Rosa, Alessandra, et al. “The X-Ray View of Optically Selected Dual AGN.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 519, no. 4, Oxford University Press, 2022, pp. 5149–60, doi:<a href=\"https://doi.org/10.1093/mnras/stac3664\">10.1093/mnras/stac3664</a>.","apa":"De Rosa, A., Vignali, C., Severgnini, P., Bianchi, S., Bogdanović, T., Charisi, M., … Serafinelli, R. (2022). The X-ray view of optically selected dual AGN. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stac3664\">https://doi.org/10.1093/mnras/stac3664</a>"},"intvolume":"       519","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2022","date_published":"2022-12-15T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.1093/mnras/stac3664","open_access":"1"}]},{"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2022","intvolume":"     13681","main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2208.03160","open_access":"1"}],"date_published":"2022-10-23T00:00:00Z","quality_controlled":"1","type":"conference","external_id":{"isi":["000904104000021"],"arxiv":["2208.03160"]},"_id":"11839","abstract":[{"lang":"eng","text":"It is a highly desirable property for deep networks to be robust against\r\nsmall input changes. One popular way to achieve this property is by designing\r\nnetworks with a small Lipschitz constant. In this work, we propose a new\r\ntechnique for constructing such Lipschitz networks that has a number of\r\ndesirable properties: it can be applied to any linear network layer\r\n(fully-connected or convolutional), it provides formal guarantees on the\r\nLipschitz constant, it is easy to implement and efficient to run, and it can be\r\ncombined with any training objective and optimization method. In fact, our\r\ntechnique is the first one in the literature that achieves all of these\r\nproperties simultaneously. Our main contribution is a rescaling-based weight\r\nmatrix parametrization that guarantees each network layer to have a Lipschitz\r\nconstant of at most 1 and results in the learned weight matrices to be close to\r\northogonal. Hence we call such layers almost-orthogonal Lipschitz (AOL).\r\nExperiments and ablation studies in the context of image classification with\r\ncertified robust accuracy confirm that AOL layers achieve results that are on\r\npar with most existing methods. Yet, they are simpler to implement and more\r\nbroadly applicable, because they do not require computationally expensive\r\nmatrix orthogonalization or inversion steps as part of the network\r\narchitecture. We provide code at https://github.com/berndprach/AOL."}],"language":[{"iso":"eng"}],"citation":{"ieee":"B. Prach and C. Lampert, “Almost-orthogonal layers for efficient general-purpose Lipschitz networks,” in <i>Computer Vision – ECCV 2022</i>, Tel Aviv, Israel, 2022, vol. 13681, pp. 350–365.","short":"B. Prach, C. Lampert, in:, Computer Vision – ECCV 2022, Springer Nature, 2022, pp. 350–365.","mla":"Prach, Bernd, and Christoph Lampert. “Almost-Orthogonal Layers for Efficient General-Purpose Lipschitz Networks.” <i>Computer Vision – ECCV 2022</i>, vol. 13681, Springer Nature, 2022, pp. 350–65, doi:<a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">10.1007/978-3-031-19803-8_21</a>.","apa":"Prach, B., &#38; Lampert, C. (2022). Almost-orthogonal layers for efficient general-purpose Lipschitz networks. In <i>Computer Vision – ECCV 2022</i> (Vol. 13681, pp. 350–365). Tel Aviv, Israel: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">https://doi.org/10.1007/978-3-031-19803-8_21</a>","ista":"Prach B, Lampert C. 2022. Almost-orthogonal layers for efficient general-purpose Lipschitz networks. Computer Vision – ECCV 2022. ECCV: European Conference on Computer Vision, LNCS, vol. 13681, 350–365.","ama":"Prach B, Lampert C. Almost-orthogonal layers for efficient general-purpose Lipschitz networks. In: <i>Computer Vision – ECCV 2022</i>. Vol 13681. Springer Nature; 2022:350-365. doi:<a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">10.1007/978-3-031-19803-8_21</a>","chicago":"Prach, Bernd, and Christoph Lampert. “Almost-Orthogonal Layers for Efficient General-Purpose Lipschitz Networks.” In <i>Computer Vision – ECCV 2022</i>, 13681:350–65. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">https://doi.org/10.1007/978-3-031-19803-8_21</a>."},"day":"23","page":"350-365","status":"public","scopus_import":"1","isi":1,"publication":"Computer Vision – ECCV 2022","date_updated":"2026-04-07T11:49:51Z","arxiv":1,"publication_identifier":{"isbn":["9783031198021"],"eisbn":["9783031198038"]},"oa_version":"Preprint","title":"Almost-orthogonal layers for efficient general-purpose Lipschitz networks","alternative_title":["LNCS"],"date_created":"2022-08-12T15:09:47Z","conference":{"end_date":"2022-10-27","location":"Tel Aviv, Israel","name":"ECCV: European Conference on Computer Vision","start_date":"2022-10-23"},"publication_status":"published","publisher":"Springer Nature","article_processing_charge":"No","corr_author":"1","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"19759"}]},"doi":"10.1007/978-3-031-19803-8_21","oa":1,"department":[{"_id":"GradSch"},{"_id":"ChLa"}],"month":"10","volume":13681,"author":[{"id":"2D561D42-C427-11E9-89B4-9C1AE6697425","first_name":"Bernd","last_name":"Prach","full_name":"Prach, Bernd"},{"full_name":"Lampert, Christoph","last_name":"Lampert","first_name":"Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8622-7887"}]},{"acknowledgement":"We thank the scientific service units at ISTA, specifically the lab support facility and imaging & optics facility for their support; Nicolas Armel for performing the Mass Spectrometry. We thank Alexandra Lang and Tanja Peilnsteiner for their help in human brain tissue collection, Rouven Schulz for his insights into the functional assays We thank all members of the Siegert group for constant feedback on the project and Margaret Maes, Rouven Schulz, and Marco Benevento for feedback on the manuscript. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant No. 715571 to S.S.) and from the Gesellschaft für Forschungsförderung Niederösterreich (grant No. Sc19-017 to V.H.).","oa":1,"doi":"10.1016/j.isci.2022.104580","author":[{"full_name":"Bartalska, Katarina","last_name":"Bartalska","first_name":"Katarina","id":"4D883232-F248-11E8-B48F-1D18A9856A87"},{"id":"32B7C918-F248-11E8-B48F-1D18A9856A87","first_name":"Verena","full_name":"Hübschmann, Verena","last_name":"Hübschmann"},{"orcid":"0000-0003-4309-2251","id":"4B51CE74-F248-11E8-B48F-1D18A9856A87","first_name":"Medina","last_name":"Korkut","full_name":"Korkut, Medina"},{"last_name":"Cubero","full_name":"Cubero, Ryan J","id":"850B2E12-9CD4-11E9-837F-E719E6697425","first_name":"Ryan J","orcid":"0000-0003-0002-1867"},{"first_name":"Alessandro","id":"41CB84B2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2356-9403","last_name":"Venturino","full_name":"Venturino, Alessandro"},{"first_name":"Karl","full_name":"Rössler, Karl","last_name":"Rössler"},{"first_name":"Thomas","last_name":"Czech","full_name":"Czech, Thomas"},{"last_name":"Siegert","full_name":"Siegert, Sandra","first_name":"Sandra","id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8635-0877"}],"volume":25,"project":[{"_id":"25D4A630-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"715571","name":"Microglia action towards neuronal circuit formation and function in health and disease"},{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"},{"grant_number":"SC19-017","_id":"9B99D380-BA93-11EA-9121-9846C619BF3A","name":"How human microglia shape developing neurons during health and inflammation"}],"article_type":"original","department":[{"_id":"SaSi"}],"month":"07","corr_author":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes","publisher":"Elsevier","pmid":1,"related_material":{"record":[{"relation":"other","status":"public","id":"12117"},{"relation":"dissertation_contains","status":"public","id":"20074"}]},"publication_status":"published","file":[{"access_level":"open_access","file_size":19400048,"date_created":"2022-07-04T08:19:25Z","success":1,"content_type":"application/pdf","file_name":"2022_iScience_Bartalska.pdf","checksum":"a470b74e1b3796c710189c81a4cd4329","date_updated":"2022-07-04T08:19:25Z","creator":"cchlebak","file_id":"11480","relation":"main_file"}],"publication_identifier":{"eissn":["2589-0042"]},"title":"A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation","date_created":"2022-07-03T22:01:33Z","oa_version":"Published Version","file_date_updated":"2022-07-04T08:19:25Z","date_updated":"2026-04-07T11:51:43Z","publication":"iScience","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"isi":1,"status":"public","ec_funded":1,"issue":"7","scopus_import":"1","language":[{"iso":"eng"}],"_id":"11478","abstract":[{"lang":"eng","text":"Cerebral organoids differentiated from human-induced pluripotent stem cells (hiPSC) provide a unique opportunity to investigate brain development. However, organoids usually lack microglia, brain-resident immune cells, which are present in the early embryonic brain and participate in neuronal circuit development. Here, we find IBA1+ microglia-like cells alongside retinal cups between week 3 and 4 in 2.5D culture with an unguided retinal organoid differentiation protocol. Microglia do not infiltrate the neuroectoderm and instead enrich within non-pigmented, 3D-cystic compartments that develop in parallel to the 3D-retinal organoids. When we guide the retinal organoid differentiation with low-dosed BMP4, we prevent cup development and enhance microglia and 3D-cysts formation. Mass spectrometry identifies these 3D-cysts to express mesenchymal and epithelial markers. We confirmed this microglia-preferred environment also within the unguided protocol, providing insight into microglial behavior and migration and offer a model to study how they enter and distribute within the human brain."}],"external_id":{"pmid":["35789843"],"isi":["000830428500005"]},"type":"journal_article","quality_controlled":"1","has_accepted_license":"1","citation":{"apa":"Bartalska, K., Hübschmann, V., Korkut, M., Cubero, R. J., Venturino, A., Rössler, K., … Siegert, S. (2022). A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation. <i>IScience</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.isci.2022.104580\">https://doi.org/10.1016/j.isci.2022.104580</a>","mla":"Bartalska, Katarina, et al. “A Systematic Characterization of Microglia-like Cell Occurrence during Retinal Organoid Differentiation.” <i>IScience</i>, vol. 25, no. 7, 104580, Elsevier, 2022, doi:<a href=\"https://doi.org/10.1016/j.isci.2022.104580\">10.1016/j.isci.2022.104580</a>.","ieee":"K. Bartalska <i>et al.</i>, “A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation,” <i>iScience</i>, vol. 25, no. 7. Elsevier, 2022.","short":"K. Bartalska, V. Hübschmann, M. Korkut, R.J. Cubero, A. Venturino, K. Rössler, T. Czech, S. Siegert, IScience 25 (2022).","chicago":"Bartalska, Katarina, Verena Hübschmann, Medina Korkut, Ryan J Cubero, Alessandro Venturino, Karl Rössler, Thomas Czech, and Sandra Siegert. “A Systematic Characterization of Microglia-like Cell Occurrence during Retinal Organoid Differentiation.” <i>IScience</i>. Elsevier, 2022. <a href=\"https://doi.org/10.1016/j.isci.2022.104580\">https://doi.org/10.1016/j.isci.2022.104580</a>.","ama":"Bartalska K, Hübschmann V, Korkut M, et al. A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation. <i>iScience</i>. 2022;25(7). doi:<a href=\"https://doi.org/10.1016/j.isci.2022.104580\">10.1016/j.isci.2022.104580</a>","ista":"Bartalska K, Hübschmann V, Korkut M, Cubero RJ, Venturino A, Rössler K, Czech T, Siegert S. 2022. A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation. iScience. 25(7), 104580."},"day":"15","article_number":"104580","intvolume":"        25","year":"2022","ddc":["610"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2022-07-15T00:00:00Z"},{"publication_identifier":{"issn":["0302-9743"]},"oa_version":"Published Version","alternative_title":["LNCS"],"date_created":"2022-08-08T17:09:09Z","title":"Abstract monitors for quantitative specifications","publication_status":"published","conference":{"start_date":"2022-09-28","name":"RV: Runtime Verification","location":"Tbilisi, Georgia","end_date":"2022-09-30"},"file":[{"checksum":"05c7dcfbb9053a98f46441fb2eccb213","file_name":"2022_LNCS_RV_Henzinger.pdf","date_updated":"2023-01-20T07:34:50Z","relation":"main_file","creator":"dernst","file_id":"12317","access_level":"open_access","content_type":"application/pdf","success":1,"file_size":477110,"date_created":"2023-01-20T07:34:50Z"}],"publisher":"Springer Nature","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"corr_author":"1","article_processing_charge":"Yes","related_material":{"record":[{"status":"public","id":"20147","relation":"dissertation_contains"}]},"acknowledgement":"We thank the anonymous reviewers for their helpful comments. This work was supported in part by the ERC-2020-AdG 101020093.","doi":"10.1007/978-3-031-17196-3_11","oa":1,"project":[{"name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","grant_number":"101020093"}],"month":"09","department":[{"_id":"GradSch"},{"_id":"ToHe"}],"author":[{"last_name":"Henzinger","full_name":"Henzinger, Thomas A","first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2985-7724"},{"first_name":"Nicolas Adrien","id":"b26baa86-3308-11ec-87b0-8990f34baa85","last_name":"Mazzocchi","full_name":"Mazzocchi, Nicolas Adrien"},{"id":"8C6B42F8-C8E6-11E9-A03A-F2DCE5697425","first_name":"Naci E","full_name":"Sarac, Naci E","last_name":"Sarac"}],"volume":13498,"year":"2022","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","ddc":["000"],"intvolume":"     13498","date_published":"2022-09-23T00:00:00Z","type":"conference","quality_controlled":"1","_id":"11775","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Quantitative monitoring can be universal and approximate: For every finite sequence of observations, the specification provides a value and the monitor outputs a best-effort approximation of it. The quality of the approximation may depend on the resources that are available to the monitor. By taking to the limit the sequences of specification values and monitor outputs, we obtain precision-resource trade-offs also for limit monitoring. This paper provides a formal framework for studying such trade-offs using an abstract interpretation for monitors: For each natural number n, the aggregate semantics of a monitor at time n is an equivalence relation over all sequences of at most n observations so that two equivalent sequences are indistinguishable to the monitor and thus mapped to the same output. This abstract interpretation of quantitative monitors allows us to measure the number of equivalence classes (or “resource use”) that is necessary for a certain precision up to a certain time, or at any time. Our framework offers several insights. For example, we identify a family of specifications for which any resource-optimal exact limit monitor is independent of any error permitted over finite traces. Moreover, we present a specification for which any resource-optimal approximate limit monitor does not minimize its resource use at any time. "}],"external_id":{"isi":["000866539700011"]},"has_accepted_license":"1","citation":{"ista":"Henzinger TA, Mazzocchi NA, Sarac NE. 2022. Abstract monitors for quantitative specifications. 22nd International Conference on Runtime Verification. RV: Runtime Verification, LNCS, vol. 13498, 200–220.","ama":"Henzinger TA, Mazzocchi NA, Sarac NE. Abstract monitors for quantitative specifications. In: <i>22nd International Conference on Runtime Verification</i>. Vol 13498. Springer Nature; 2022:200-220. doi:<a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">10.1007/978-3-031-17196-3_11</a>","chicago":"Henzinger, Thomas A, Nicolas Adrien Mazzocchi, and Naci E Sarac. “Abstract Monitors for Quantitative Specifications.” In <i>22nd International Conference on Runtime Verification</i>, 13498:200–220. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">https://doi.org/10.1007/978-3-031-17196-3_11</a>.","short":"T.A. Henzinger, N.A. Mazzocchi, N.E. Sarac, in:, 22nd International Conference on Runtime Verification, Springer Nature, 2022, pp. 200–220.","ieee":"T. A. Henzinger, N. A. Mazzocchi, and N. E. Sarac, “Abstract monitors for quantitative specifications,” in <i>22nd International Conference on Runtime Verification</i>, Tbilisi, Georgia, 2022, vol. 13498, pp. 200–220.","mla":"Henzinger, Thomas A., et al. “Abstract Monitors for Quantitative Specifications.” <i>22nd International Conference on Runtime Verification</i>, vol. 13498, Springer Nature, 2022, pp. 200–20, doi:<a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">10.1007/978-3-031-17196-3_11</a>.","apa":"Henzinger, T. A., Mazzocchi, N. A., &#38; Sarac, N. E. (2022). Abstract monitors for quantitative specifications. In <i>22nd International Conference on Runtime Verification</i> (Vol. 13498, pp. 200–220). Tbilisi, Georgia: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">https://doi.org/10.1007/978-3-031-17196-3_11</a>"},"day":"23","status":"public","page":"200-220","scopus_import":"1","ec_funded":1,"file_date_updated":"2023-01-20T07:34:50Z","isi":1,"publication":"22nd International Conference on Runtime Verification","date_updated":"2026-04-07T12:02:56Z"},{"article_processing_charge":"No","corr_author":"1","publisher":"Springer Nature","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"20920"},{"relation":"dissertation_contains","id":"20556","status":"public"}]},"doi":"10.1007/978-3-031-15979-4_13","oa":1,"acknowledgement":"We would like to thank the authors of [BHR+21] for clarifying several questions we had\r\nregarding their results. Pavel Hubá£ek was supported by the Grant Agency of the Czech\r\nRepublic under the grant agreement no. 19-27871X and by the Charles University project\r\nUNCE/SCI/004. Chethan Kamath is supported by Azrieli International Postdoctoral Fellowship\r\nand ISF grants 484/18 and 1789/19. Karen Klein was supported in part by ERC CoG grant\r\n724307 and conducted part of this work at Institute of Science and Technology Austria.","author":[{"orcid":"0000-0003-2027-5549","first_name":"Charlotte","id":"0f78d746-dc7d-11ea-9b2f-83f92091afe7","last_name":"Hoffmann","full_name":"Hoffmann, Charlotte"},{"first_name":"Pavel","last_name":"Hubáček","full_name":"Hubáček, Pavel"},{"full_name":"Kamath, Chethan","last_name":"Kamath","first_name":"Chethan"},{"full_name":"Klein, Karen","last_name":"Klein","first_name":"Karen"},{"full_name":"Pietrzak, Krzysztof Z","last_name":"Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654"}],"volume":13508,"month":"10","department":[{"_id":"KrPi"}],"publication_identifier":{"eisbn":["9783031159794"],"isbn":["9783031159787"],"eissn":["1611-3349"],"issn":["0302-9743"]},"title":"Practical statistically-sound proofs of exponentiation in any group","date_created":"2023-01-12T12:12:07Z","alternative_title":["LNCS"],"oa_version":"Preprint","publication_status":"published","conference":{"start_date":"2022-08-15","name":"CRYPTO: International Cryptology Conference","location":"Santa Barbara, CA, United States","end_date":"2022-08-18"},"status":"public","page":"370-399","scopus_import":"1","publication":"Advances in Cryptology – CRYPTO 2022","date_updated":"2026-04-07T12:34:30Z","isi":1,"intvolume":"     13508","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2022","date_published":"2022-10-13T00:00:00Z","main_file_link":[{"url":"https://eprint.iacr.org/2022/1021","open_access":"1"}],"external_id":{"isi":["000886792700013"]},"_id":"12176","abstract":[{"text":"A proof of exponentiation (PoE) in a group G of unknown order allows a prover to convince a verifier that a tuple (x,q,T,y)∈G×N×N×G satisfies xqT=y. This primitive has recently found exciting applications in the constructions of verifiable delay functions and succinct arguments of knowledge. The most practical PoEs only achieve soundness either under computational assumptions, i.e., they are arguments (Wesolowski, Journal of Cryptology 2020), or in groups that come with the promise of not having any small subgroups (Pietrzak, ITCS 2019). The only statistically-sound PoE in general groups of unknown order is due to Block et al. (CRYPTO 2021), and can be seen as an elaborate parallel repetition of Pietrzak’s PoE: to achieve λ bits of security, say λ=80, the number of repetitions required (and thus the blow-up in communication) is as large as λ.\r\n\r\nIn this work, we propose a statistically-sound PoE for the case where the exponent q is the product of all primes up to some bound B. We show that, in this case, it suffices to run only λ/log(B) parallel instances of Pietrzak’s PoE, which reduces the concrete proof-size compared to Block et al. by an order of magnitude. Furthermore, we show that in the known applications where PoEs are used as a building block such structured exponents are viable. Finally, we also discuss batching of our PoE, showing that many proofs (for the same G and q but different x and T) can be batched by adding only a single element to the proof per additional statement.","lang":"eng"}],"language":[{"iso":"eng"}],"quality_controlled":"1","type":"conference","citation":{"chicago":"Hoffmann, Charlotte, Pavel Hubáček, Chethan Kamath, Karen Klein, and Krzysztof Z Pietrzak. “Practical Statistically-Sound Proofs of Exponentiation in Any Group.” In <i>Advances in Cryptology – CRYPTO 2022</i>, 13508:370–99. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-15979-4_13\">https://doi.org/10.1007/978-3-031-15979-4_13</a>.","ama":"Hoffmann C, Hubáček P, Kamath C, Klein K, Pietrzak KZ. Practical statistically-sound proofs of exponentiation in any group. In: <i>Advances in Cryptology – CRYPTO 2022</i>. Vol 13508. Springer Nature; 2022:370-399. doi:<a href=\"https://doi.org/10.1007/978-3-031-15979-4_13\">10.1007/978-3-031-15979-4_13</a>","ista":"Hoffmann C, Hubáček P, Kamath C, Klein K, Pietrzak KZ. 2022. Practical statistically-sound proofs of exponentiation in any group. Advances in Cryptology – CRYPTO 2022. CRYPTO: International Cryptology Conference, LNCS, vol. 13508, 370–399.","apa":"Hoffmann, C., Hubáček, P., Kamath, C., Klein, K., &#38; Pietrzak, K. Z. (2022). Practical statistically-sound proofs of exponentiation in any group. In <i>Advances in Cryptology – CRYPTO 2022</i> (Vol. 13508, pp. 370–399). Santa Barbara, CA, United States: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-15979-4_13\">https://doi.org/10.1007/978-3-031-15979-4_13</a>","mla":"Hoffmann, Charlotte, et al. “Practical Statistically-Sound Proofs of Exponentiation in Any Group.” <i>Advances in Cryptology – CRYPTO 2022</i>, vol. 13508, Springer Nature, 2022, pp. 370–99, doi:<a href=\"https://doi.org/10.1007/978-3-031-15979-4_13\">10.1007/978-3-031-15979-4_13</a>.","short":"C. Hoffmann, P. Hubáček, C. Kamath, K. Klein, K.Z. Pietrzak, in:, Advances in Cryptology – CRYPTO 2022, Springer Nature, 2022, pp. 370–399.","ieee":"C. Hoffmann, P. Hubáček, C. Kamath, K. Klein, and K. Z. Pietrzak, “Practical statistically-sound proofs of exponentiation in any group,” in <i>Advances in Cryptology – CRYPTO 2022</i>, Santa Barbara, CA, United States, 2022, vol. 13508, pp. 370–399."},"day":"13"},{"author":[{"last_name":"Glas","full_name":"Glas, Jakob","id":"d6423cba-dc74-11ea-a0a7-ee61689ff5fb","first_name":"Jakob"},{"full_name":"Hochfilzer, Leonhard","last_name":"Hochfilzer","first_name":"Leonhard"}],"publication":"arXiv","date_updated":"2026-04-07T12:53:53Z","month":"08","department":[{"_id":"TiBr"}],"oa":1,"doi":"10.48550/arXiv.2208.05422","related_material":{"record":[{"id":"18705","status":"public","relation":"later_version"},{"relation":"dissertation_contains","id":"18132","status":"public"}]},"article_processing_charge":"No","corr_author":"1","status":"public","citation":{"ista":"Glas J, Hochfilzer L. On a question of Davenport and diagonal cubic forms over Fq(t). arXiv, 2208.05422.","ama":"Glas J, Hochfilzer L. On a question of Davenport and diagonal cubic forms over Fq(t). <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2208.05422\">10.48550/arXiv.2208.05422</a>","chicago":"Glas, Jakob, and Leonhard Hochfilzer. “On a Question of Davenport and Diagonal Cubic Forms over Fq(T).” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2208.05422\">https://doi.org/10.48550/arXiv.2208.05422</a>.","ieee":"J. Glas and L. Hochfilzer, “On a question of Davenport and diagonal cubic forms over Fq(t),” <i>arXiv</i>. .","short":"J. Glas, L. Hochfilzer, ArXiv (n.d.).","mla":"Glas, Jakob, and Leonhard Hochfilzer. “On a Question of Davenport and Diagonal Cubic Forms over Fq(T).” <i>ArXiv</i>, 2208.05422, doi:<a href=\"https://doi.org/10.48550/arXiv.2208.05422\">10.48550/arXiv.2208.05422</a>.","apa":"Glas, J., &#38; Hochfilzer, L. (n.d.). On a question of Davenport and diagonal cubic forms over Fq(t). <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2208.05422\">https://doi.org/10.48550/arXiv.2208.05422</a>"},"day":"10","external_id":{"arxiv":["2208.05422"]},"abstract":[{"lang":"eng","text":"Given a non-singular diagonal cubic hypersurface X⊂Pn−1 over Fq(t) with char(Fq)≠3, we show that the number of rational points of height at most |P| is O(|P|3+ε) for n=6 and O(|P|2+ε) for n=4. In fact, if n=4 and char(Fq)>3 we prove that the number of rational points away from any rational line contained in X is bounded by O(|P|3/2+ε). From the result in 6 variables we deduce weak approximation for diagonal cubic hypersurfaces for n≥7 over Fq(t) when char(Fq)>3 and handle Waring's problem for cubes in 7 variables over Fq(t) when char(Fq)≠3. Our results answer a question of Davenport regarding the number of solutions of bounded height to x31+x32+x33=x34+x35+x36 with xi∈Fq[t]."}],"_id":"18293","language":[{"iso":"eng"}],"publication_status":"draft","type":"preprint","title":"On a question of Davenport and diagonal cubic forms over Fq(t)","OA_place":"repository","date_created":"2024-10-10T12:46:41Z","date_published":"2022-08-10T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2208.05422","open_access":"1"}],"oa_version":"Preprint","article_number":"2208.05422","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"year":"2022"},{"publisher":"Springer Nature","article_processing_charge":"No","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"18667"}]},"series_title":"AWMS","oa":1,"doi":"10.1007/978-3-030-95519-9_1","acknowledgement":"This project started during the Women in Computational Topology workshop held in Canberra in July of 2019. All authors are very grateful for its organisation and the financial support for the workshop from the Mathematical Sciences Institute at ANU, the US National Science Foundation through the award CCF-1841455, the Australian Mathematical Sciences Institute and the Association for Women in Mathematics. AG is supported by the Swiss National Science Foundation grant CRSII5_177237. TH is supported by the European Research Council (ERC) Horizon 2020 project “Alpha Shape Theory Extended” No. 788183. KM is supported by the ERC Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 859860. VR was supported by Australian Research Council Future Fellowship FT140100604 during the early stages of this project.","month":"01","department":[{"_id":"HeEd"}],"project":[{"grant_number":"788183","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Alpha Shape Theory Extended"}],"author":[{"first_name":"Bea","full_name":"Bleile, Bea","last_name":"Bleile"},{"first_name":"Adélie","full_name":"Garin, Adélie","last_name":"Garin"},{"id":"4879BB4E-F248-11E8-B48F-1D18A9856A87","first_name":"Teresa","orcid":"0000-0002-1780-2689","last_name":"Heiss","full_name":"Heiss, Teresa"},{"full_name":"Maggs, Kelly","last_name":"Maggs","first_name":"Kelly"},{"last_name":"Robins","full_name":"Robins, Vanessa","first_name":"Vanessa"}],"volume":30,"arxiv":1,"publication_identifier":{"eisbn":["9783030955199"],"isbn":["9783030955182"]},"place":"Cham","oa_version":"Preprint","title":"The persistent homology of dual digital image constructions","alternative_title":["Association for Women in Mathematics Series"],"date_created":"2022-06-07T08:21:11Z","publication_status":"published","page":"1-26","status":"public","scopus_import":"1","editor":[{"last_name":"Gasparovic","full_name":"Gasparovic, Ellen","first_name":"Ellen"},{"first_name":"Vanessa","full_name":"Robins, Vanessa","last_name":"Robins"},{"first_name":"Katharine","full_name":"Turner, Katharine","last_name":"Turner"}],"ec_funded":1,"publication":"Research in Computational Topology 2","date_updated":"2026-04-07T12:54:09Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2022","intvolume":"        30","main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2102.11397","open_access":"1"}],"date_published":"2022-01-27T00:00:00Z","quality_controlled":"1","type":"book_chapter","external_id":{"arxiv":["2102.11397"]},"_id":"11440","abstract":[{"lang":"eng","text":"To compute the persistent homology of a grayscale digital image one needs to build a simplicial or cubical complex from it. For cubical complexes, the two commonly used constructions (corresponding to direct and indirect digital adjacencies) can give different results for the same image. The two constructions are almost dual to each other, and we use this relationship to extend and modify the cubical complexes to become dual filtered cell complexes. We derive a general relationship between the persistent homology of two dual filtered cell complexes, and also establish how various modifications to a filtered complex change the persistence diagram. Applying these results to images, we derive a method to transform the persistence diagram computed using one type of cubical complex into a persistence diagram for the other construction. This means software for computing persistent homology from images can now be easily adapted to produce results for either of the two cubical complex constructions without additional low-level code implementation."}],"edition":"1","language":[{"iso":"eng"}],"day":"27","citation":{"chicago":"Bleile, Bea, Adélie Garin, Teresa Heiss, Kelly Maggs, and Vanessa Robins. “The Persistent Homology of Dual Digital Image Constructions.” In <i>Research in Computational Topology 2</i>, edited by Ellen Gasparovic, Vanessa Robins, and Katharine Turner, 1st ed., 30:1–26. AWMS. Cham: Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-030-95519-9_1\">https://doi.org/10.1007/978-3-030-95519-9_1</a>.","ama":"Bleile B, Garin A, Heiss T, Maggs K, Robins V. The persistent homology of dual digital image constructions. In: Gasparovic E, Robins V, Turner K, eds. <i>Research in Computational Topology 2</i>. Vol 30. 1st ed. AWMS. Cham: Springer Nature; 2022:1-26. doi:<a href=\"https://doi.org/10.1007/978-3-030-95519-9_1\">10.1007/978-3-030-95519-9_1</a>","ista":"Bleile B, Garin A, Heiss T, Maggs K, Robins V. 2022.The persistent homology of dual digital image constructions. In: Research in Computational Topology 2. Association for Women in Mathematics Series, vol. 30, 1–26.","apa":"Bleile, B., Garin, A., Heiss, T., Maggs, K., &#38; Robins, V. (2022). The persistent homology of dual digital image constructions. In E. Gasparovic, V. Robins, &#38; K. Turner (Eds.), <i>Research in Computational Topology 2</i> (1st ed., Vol. 30, pp. 1–26). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-95519-9_1\">https://doi.org/10.1007/978-3-030-95519-9_1</a>","mla":"Bleile, Bea, et al. “The Persistent Homology of Dual Digital Image Constructions.” <i>Research in Computational Topology 2</i>, edited by Ellen Gasparovic et al., 1st ed., vol. 30, Springer Nature, 2022, pp. 1–26, doi:<a href=\"https://doi.org/10.1007/978-3-030-95519-9_1\">10.1007/978-3-030-95519-9_1</a>.","short":"B. Bleile, A. Garin, T. Heiss, K. Maggs, V. Robins, in:, E. Gasparovic, V. Robins, K. Turner (Eds.), Research in Computational Topology 2, 1st ed., Springer Nature, Cham, 2022, pp. 1–26.","ieee":"B. Bleile, A. Garin, T. Heiss, K. Maggs, and V. Robins, “The persistent homology of dual digital image constructions,” in <i>Research in Computational Topology 2</i>, 1st ed., vol. 30, E. Gasparovic, V. Robins, and K. Turner, Eds. Cham: Springer Nature, 2022, pp. 1–26."}},{"date_updated":"2026-04-07T13:01:26Z","publication":"Advances in Cryptology – EUROCRYPT 2022","isi":1,"ec_funded":1,"scopus_import":"1","status":"public","page":"815–844","day":"25","citation":{"ama":"Alwen J, Auerbach B, Cueto Noval M, et al. CoCoA: Concurrent continuous group key agreement. In: <i>Advances in Cryptology – EUROCRYPT 2022</i>. Vol 13276. Cham: Springer Nature; 2022:815–844. doi:<a href=\"https://doi.org/10.1007/978-3-031-07085-3_28\">10.1007/978-3-031-07085-3_28</a>","ista":"Alwen J, Auerbach B, Cueto Noval M, Klein K, Pascual Perez G, Pietrzak KZ, Walter M. 2022. CoCoA: Concurrent continuous group key agreement. Advances in Cryptology – EUROCRYPT 2022. EUROCRYPT: Theory and Applications of Cryptology and Information Security, LNCS, vol. 13276, 815–844.","chicago":"Alwen, Joël, Benedikt Auerbach, Miguel Cueto Noval, Karen Klein, Guillermo Pascual Perez, Krzysztof Z Pietrzak, and Michael Walter. “CoCoA: Concurrent Continuous Group Key Agreement.” In <i>Advances in Cryptology – EUROCRYPT 2022</i>, 13276:815–844. Cham: Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-07085-3_28\">https://doi.org/10.1007/978-3-031-07085-3_28</a>.","mla":"Alwen, Joël, et al. “CoCoA: Concurrent Continuous Group Key Agreement.” <i>Advances in Cryptology – EUROCRYPT 2022</i>, vol. 13276, Springer Nature, 2022, pp. 815–844, doi:<a href=\"https://doi.org/10.1007/978-3-031-07085-3_28\">10.1007/978-3-031-07085-3_28</a>.","short":"J. Alwen, B. Auerbach, M. Cueto Noval, K. Klein, G. Pascual Perez, K.Z. Pietrzak, M. Walter, in:, Advances in Cryptology – EUROCRYPT 2022, Springer Nature, Cham, 2022, pp. 815–844.","ieee":"J. Alwen <i>et al.</i>, “CoCoA: Concurrent continuous group key agreement,” in <i>Advances in Cryptology – EUROCRYPT 2022</i>, Trondheim, Norway, 2022, vol. 13276, pp. 815–844.","apa":"Alwen, J., Auerbach, B., Cueto Noval, M., Klein, K., Pascual Perez, G., Pietrzak, K. Z., &#38; Walter, M. (2022). CoCoA: Concurrent continuous group key agreement. In <i>Advances in Cryptology – EUROCRYPT 2022</i> (Vol. 13276, pp. 815–844). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-07085-3_28\">https://doi.org/10.1007/978-3-031-07085-3_28</a>"},"external_id":{"isi":["000832305300028"]},"_id":"11476","abstract":[{"text":"Messaging platforms like Signal are widely deployed and provide strong security in an asynchronous setting. It is a challenging problem to construct a protocol with similar security guarantees that can efficiently scale to large groups. A major bottleneck are the frequent key rotations users need to perform to achieve post compromise forward security.\r\n\r\nIn current proposals – most notably in TreeKEM (which is part of the IETF’s Messaging Layer Security (MLS) protocol draft) – for users in a group of size n to rotate their keys, they must each craft a message of size log(n) to be broadcast to the group using an (untrusted) delivery server.\r\n\r\nIn larger groups, having users sequentially rotate their keys requires too much bandwidth (or takes too long), so variants allowing any T≤n users to simultaneously rotate their keys in just 2 communication rounds have been suggested (e.g. “Propose and Commit” by MLS). Unfortunately, 2-round concurrent updates are either damaging or expensive (or both); i.e. they either result in future operations being more costly (e.g. via “blanking” or “tainting”) or are costly themselves requiring Ω(T) communication for each user [Bienstock et al., TCC’20].\r\n\r\nIn this paper we propose CoCoA; a new scheme that allows for T concurrent updates that are neither damaging nor costly. That is, they add no cost to future operations yet they only require Ω(log2(n)) communication per user. To circumvent the [Bienstock et al.] lower bound, CoCoA increases the number of rounds needed to complete all updates from 2 up to (at most) log(n); though typically fewer rounds are needed.\r\n\r\nThe key insight of our protocol is the following: in the (non-concurrent version of) TreeKEM, a delivery server which gets T concurrent update requests will approve one and reject the remaining T−1. In contrast, our server attempts to apply all of them. If more than one user requests to rotate the same key during a round, the server arbitrarily picks a winner. Surprisingly, we prove that regardless of how the server chooses the winners, all previously compromised users will recover after at most log(n) such update rounds.\r\n\r\nTo keep the communication complexity low, CoCoA is a server-aided CGKA. That is, the delivery server no longer blindly forwards packets, but instead actively computes individualized packets tailored to each user. As the server is untrusted, this change requires us to develop new mechanisms ensuring robustness of the protocol.","lang":"eng"}],"language":[{"iso":"eng"}],"quality_controlled":"1","type":"conference","date_published":"2022-05-25T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2022/251"}],"intvolume":"     13276","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2022","author":[{"first_name":"Joël","full_name":"Alwen, Joël","last_name":"Alwen"},{"orcid":"0000-0002-7553-6606","id":"D33D2B18-E445-11E9-ABB7-15F4E5697425","first_name":"Benedikt","last_name":"Auerbach","full_name":"Auerbach, Benedikt"},{"last_name":"Cueto Noval","full_name":"Cueto Noval, Miguel","first_name":"Miguel","id":"ffc563a3-f6e0-11ea-865d-e3cce03d17cc","orcid":"0000-0002-2505-4246"},{"id":"3E83A2F8-F248-11E8-B48F-1D18A9856A87","first_name":"Karen","full_name":"Klein, Karen","last_name":"Klein"},{"orcid":"0000-0001-8630-415X","id":"2D7ABD02-F248-11E8-B48F-1D18A9856A87","first_name":"Guillermo","full_name":"Pascual Perez, Guillermo","last_name":"Pascual Perez"},{"first_name":"Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654","last_name":"Pietrzak","full_name":"Pietrzak, Krzysztof Z"},{"first_name":"Michael","last_name":"Walter","full_name":"Walter, Michael"}],"volume":13276,"month":"05","department":[{"_id":"GradSch"},{"_id":"KrPi"}],"project":[{"grant_number":"682815","call_identifier":"H2020","_id":"258AA5B2-B435-11E9-9278-68D0E5697425","name":"Teaching Old Crypto New Tricks"},{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385"}],"doi":"10.1007/978-3-031-07085-3_28","oa":1,"acknowledgement":"We thank Marta Mularczyk and Yiannis Tselekounis for their very helpful feedback on an earlier draft of this paper.","related_material":{"record":[{"status":"public","id":"18088","relation":"dissertation_contains"}]},"article_processing_charge":"No","corr_author":"1","publisher":"Springer Nature","publication_status":"published","conference":{"end_date":"2022-06-03","location":"Trondheim, Norway","name":"EUROCRYPT: Theory and Applications of Cryptology and Information Security","start_date":"2022-05-30"},"date_created":"2022-06-30T16:48:00Z","title":"CoCoA: Concurrent continuous group key agreement","alternative_title":["LNCS"],"oa_version":"Preprint","place":"Cham","publication_identifier":{"isbn":["9783031070846"],"eisbn":["9783031070853"],"issn":["0302-9743"],"eissn":["1611-3349"]}},{"day":"29","citation":{"mla":"Henheik, Sven Joscha, and Asbjørn Bækgaard Lauritsen. “The BCS Energy Gap at High Density.” <i>Journal of Statistical Physics</i>, vol. 189, 5, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s10955-022-02965-9\">10.1007/s10955-022-02965-9</a>.","short":"S.J. Henheik, A.B. Lauritsen, Journal of Statistical Physics 189 (2022).","ieee":"S. J. Henheik and A. B. Lauritsen, “The BCS energy gap at high density,” <i>Journal of Statistical Physics</i>, vol. 189. Springer Nature, 2022.","apa":"Henheik, S. J., &#38; Lauritsen, A. B. (2022). The BCS energy gap at high density. <i>Journal of Statistical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10955-022-02965-9\">https://doi.org/10.1007/s10955-022-02965-9</a>","ama":"Henheik SJ, Lauritsen AB. The BCS energy gap at high density. <i>Journal of Statistical Physics</i>. 2022;189. doi:<a href=\"https://doi.org/10.1007/s10955-022-02965-9\">10.1007/s10955-022-02965-9</a>","ista":"Henheik SJ, Lauritsen AB. 2022. The BCS energy gap at high density. Journal of Statistical Physics. 189, 5.","chicago":"Henheik, Sven Joscha, and Asbjørn Bækgaard Lauritsen. “The BCS Energy Gap at High Density.” <i>Journal of Statistical Physics</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s10955-022-02965-9\">https://doi.org/10.1007/s10955-022-02965-9</a>."},"has_accepted_license":"1","external_id":{"isi":["000833007200002"]},"abstract":[{"text":"We study the BCS energy gap Ξ in the high–density limit and derive an asymptotic formula, which strongly depends on the strength of the interaction potential V on the Fermi surface. In combination with the recent result by one of us (Math. Phys. Anal. Geom. 25, 3, 2022) on the critical temperature Tc at high densities, we prove the universality of the ratio of the energy gap and the critical temperature.","lang":"eng"}],"_id":"11732","language":[{"iso":"eng"}],"quality_controlled":"1","type":"journal_article","date_published":"2022-07-29T00:00:00Z","intvolume":"       189","article_number":"5","ddc":["530"],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","year":"2022","publication":"Journal of Statistical Physics","date_updated":"2026-04-07T13:01:40Z","isi":1,"file_date_updated":"2022-08-08T07:36:34Z","ec_funded":1,"scopus_import":"1","status":"public","file":[{"file_name":"2022_JourStatisticalPhysics_Henheik.pdf","checksum":"b398c4dbf65f71d417981d6e366427e9","file_id":"11746","relation":"main_file","creator":"dernst","date_updated":"2022-08-08T07:36:34Z","access_level":"open_access","file_size":419563,"date_created":"2022-08-08T07:36:34Z","content_type":"application/pdf","success":1}],"publication_status":"published","title":"The BCS energy gap at high density","date_created":"2022-08-05T11:36:56Z","oa_version":"Published Version","keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"publication_identifier":{"eissn":["1572-9613"],"issn":["0022-4715"]},"volume":189,"author":[{"orcid":"0000-0003-1106-327X","id":"31d731d7-d235-11ea-ad11-b50331c8d7fb","first_name":"Sven Joscha","full_name":"Henheik, Sven Joscha","last_name":"Henheik"},{"last_name":"Lauritsen","full_name":"Lauritsen, Asbjørn Bækgaard","orcid":"0000-0003-4476-2288","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","first_name":"Asbjørn Bækgaard"}],"department":[{"_id":"GradSch"},{"_id":"LaEr"},{"_id":"RoSe"}],"month":"07","project":[{"name":"Random matrices beyond Wigner-Dyson-Mehta","_id":"62796744-2b32-11ec-9570-940b20777f1d","call_identifier":"H2020","grant_number":"101020331"}],"article_type":"original","doi":"10.1007/s10955-022-02965-9","oa":1,"acknowledgement":"We are grateful to Robert Seiringer for helpful discussions and many valuable comments\r\non an earlier version of the manuscript. J.H. acknowledges partial financial support by the ERC Advanced Grant “RMTBeyond’ No. 101020331. Open access funding provided by Institute of Science and Technology (IST Austria)","related_material":{"record":[{"id":"19540","status":"public","relation":"dissertation_contains"},{"relation":"dissertation_contains","id":"18135","status":"public"}]},"article_processing_charge":"Yes (via OA deal)","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"corr_author":"1","publisher":"Springer Nature"}]