[{"acknowledgement":"We thank Nataliia Gnyliukh and Lukas Hörmayer for technical assistance and Nadine Paris for sharing PM-Cyto seeds. We gratefully acknowledge Life Science, Machine Shop and Bioimaging Facilities of IST Austria. This project has received funding from the European Research Council Advanced Grant (ETAP-742985) and the Austrian Science Fund (FWF) I 3630-B25 to J.F., the National Institutes of Health (GM067203) to W.M.G., the Netherlands Organization for Scientific Research (NWO; VIDI-864.13.001.), the Research Foundation-Flanders (FWO; Odysseus II G0D0515N) and a European Research Council Starting Grant (TORPEDO-714055) to W.S. and B.D.R., the VICI grant (865.14.001) from the Netherlands Organization for Scientific Research to M.R and D.W., the Australian Research Council and China National Distinguished Expert Project (WQ20174400441) to S.S., the MEXT/JSPS KAKENHI to K.T. (20K06685) and T.K. (20H05687 and 20H05910),  the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 665385 and the DOC Fellowship of the Austrian Academy of Sciences to L.L., the China Scholarship Council to J.C.","date_created":"2021-10-06T08:56:22Z","main_file_link":[{"open_access":"1","url":"https://www.doi.org/10.21203/rs.3.rs-266395/v3"}],"status":"public","article_processing_charge":"No","publication_identifier":{"issn":["2693-5015"]},"ec_funded":1,"publication":"Research Square","related_material":{"record":[{"relation":"later_version","id":"10223","status":"public"},{"relation":"dissertation_contains","id":"10083","status":"public"}]},"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"Bio"}],"day":"09","title":"Cell surface and intracellular auxin signalling for H+-fluxes in root growth","department":[{"_id":"JiFr"},{"_id":"NanoFab"}],"project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program"},{"_id":"261099A6-B435-11E9-9278-68D0E5697425","grant_number":"742985","call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants"},{"_id":"26538374-B435-11E9-9278-68D0E5697425","grant_number":"I03630","call_identifier":"FWF","name":"Molecular mechanisms of endocytic cargo recognition in plants"},{"_id":"26B4D67E-B435-11E9-9278-68D0E5697425","grant_number":"25351","name":"A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated Rapid Growth Inhibition in Arabidopsis Root"}],"author":[{"first_name":"Lanxin","id":"367EF8FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5607-272X","last_name":"Li","full_name":"Li, Lanxin"},{"orcid":"0000-0001-7241-2328","id":"362BF7FE-F248-11E8-B48F-1D18A9856A87","first_name":"Inge","full_name":"Verstraeten, Inge","last_name":"Verstraeten"},{"last_name":"Roosjen","full_name":"Roosjen, Mark","first_name":"Mark"},{"first_name":"Koji","full_name":"Takahashi, Koji","last_name":"Takahashi"},{"full_name":"Rodriguez Solovey, Lesia","last_name":"Rodriguez Solovey","orcid":"0000-0002-7244-7237","id":"3922B506-F248-11E8-B48F-1D18A9856A87","first_name":"Lesia"},{"last_name":"Merrin","full_name":"Merrin, Jack","first_name":"Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5145-4609"},{"full_name":"Chen, Jian","last_name":"Chen","first_name":"Jian"},{"full_name":"Shabala, Lana","last_name":"Shabala","first_name":"Lana"},{"first_name":"Wouter","full_name":"Smet, Wouter","last_name":"Smet"},{"last_name":"Ren","full_name":"Ren, Hong","first_name":"Hong"},{"full_name":"Vanneste, Steffen","last_name":"Vanneste","first_name":"Steffen"},{"last_name":"Shabala","full_name":"Shabala, Sergey","first_name":"Sergey"},{"first_name":"Bert","last_name":"De Rybel","full_name":"De Rybel, Bert"},{"full_name":"Weijers, Dolf","last_name":"Weijers","first_name":"Dolf"},{"full_name":"Kinoshita, Toshinori","last_name":"Kinoshita","first_name":"Toshinori"},{"first_name":"William M.","last_name":"Gray","full_name":"Gray, William M."},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří","full_name":"Friml, Jiří","last_name":"Friml"}],"abstract":[{"text":"Growth regulation tailors plant development to its environment. A showcase is response to gravity, where shoots bend up and roots down1. This paradox is based on opposite effects of the phytohormone auxin, which promotes cell expansion in shoots, while inhibiting it in roots via a yet unknown cellular mechanism2. Here, by combining microfluidics, live imaging, genetic engineering and phospho-proteomics in Arabidopsis thaliana, we advance our understanding how auxin inhibits root growth. We show that auxin activates two distinct, antagonistically acting signalling pathways that converge on the rapid regulation of the apoplastic pH, a causative growth determinant. Cell surface-based TRANSMEMBRANE KINASE1 (TMK1) interacts with and mediates phosphorylation and activation of plasma membrane H+-ATPases for apoplast acidification, while intracellular canonical auxin signalling promotes net cellular H+-influx, causing apoplast alkalinisation. The simultaneous activation of these two counteracting mechanisms poises the root for a rapid, fine-tuned growth modulation while navigating complex soil environment.","lang":"eng"}],"article_number":"266395","oa_version":"Preprint","date_updated":"2026-07-01T22:30:49Z","date_published":"2021-09-09T00:00:00Z","doi":"10.21203/rs.3.rs-266395/v3","language":[{"iso":"eng"}],"oa":1,"year":"2021","month":"09","_id":"10095","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"preprint","corr_author":"1","publication_status":"draft","citation":{"short":"L. Li, I. Verstraeten, M. Roosjen, K. Takahashi, L. Rodriguez Solovey, J. Merrin, J. Chen, L. Shabala, W. Smet, H. Ren, S. Vanneste, S. Shabala, B. De Rybel, D. Weijers, T. Kinoshita, W.M. Gray, J. Friml, Research Square (n.d.).","mla":"Li, Lanxin, et al. “Cell Surface and Intracellular Auxin Signalling for H+-Fluxes in Root Growth.” <i>Research Square</i>, 266395, doi:<a href=\"https://doi.org/10.21203/rs.3.rs-266395/v3\">10.21203/rs.3.rs-266395/v3</a>.","ista":"Li L, Verstraeten I, Roosjen M, Takahashi K, Rodriguez Solovey L, Merrin J, Chen J, Shabala L, Smet W, Ren H, Vanneste S, Shabala S, De Rybel B, Weijers D, Kinoshita T, Gray WM, Friml J. Cell surface and intracellular auxin signalling for H+-fluxes in root growth. Research Square, 266395.","chicago":"Li, Lanxin, Inge Verstraeten, Mark Roosjen, Koji Takahashi, Lesia Rodriguez Solovey, Jack Merrin, Jian Chen, et al. “Cell Surface and Intracellular Auxin Signalling for H+-Fluxes in Root Growth.” <i>Research Square</i>, n.d. <a href=\"https://doi.org/10.21203/rs.3.rs-266395/v3\">https://doi.org/10.21203/rs.3.rs-266395/v3</a>.","ieee":"L. Li <i>et al.</i>, “Cell surface and intracellular auxin signalling for H+-fluxes in root growth,” <i>Research Square</i>. .","apa":"Li, L., Verstraeten, I., Roosjen, M., Takahashi, K., Rodriguez Solovey, L., Merrin, J., … Friml, J. (n.d.). Cell surface and intracellular auxin signalling for H+-fluxes in root growth. <i>Research Square</i>. <a href=\"https://doi.org/10.21203/rs.3.rs-266395/v3\">https://doi.org/10.21203/rs.3.rs-266395/v3</a>","ama":"Li L, Verstraeten I, Roosjen M, et al. Cell surface and intracellular auxin signalling for H+-fluxes in root growth. <i>Research Square</i>. doi:<a href=\"https://doi.org/10.21203/rs.3.rs-266395/v3\">10.21203/rs.3.rs-266395/v3</a>"}},{"status":"public","file_date_updated":"2022-12-20T23:30:05Z","date_created":"2021-10-13T13:42:48Z","article_processing_charge":"No","publication_identifier":{"isbn":["978-3-99078-014-5"],"issn":["2663-337X"]},"related_material":{"record":[{"status":"public","id":"9160","relation":"part_of_dissertation"}]},"title":"Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis","alternative_title":["ISTA Thesis"],"day":"13","ddc":["570"],"has_accepted_license":"1","project":[{"name":"Molecular mechanisms of the cytokinin regulated endomembrane trafficking to coordinate plant organogenesis","grant_number":"24746","_id":"261821BC-B435-11E9-9278-68D0E5697425"}],"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"author":[{"id":"42FE702E-F248-11E8-B48F-1D18A9856A87","first_name":"Hana","full_name":"Semerádová, Hana","last_name":"Semerádová"}],"date_updated":"2026-04-08T07:12:06Z","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Plants maintain the capacity to develop new organs e.g. lateral roots post-embryonically throughout their whole life and thereby flexibly adapt to ever-changing environmental conditions. Plant hormones auxin and cytokinin are the main regulators of the lateral root organogenesis. Additionally to their solo activities, the interaction between auxin and\r\ncytokinin plays crucial role in fine-tuning of lateral root development and growth. In particular, cytokinin modulates auxin distribution within the developing lateral root by affecting the endomembrane trafficking of auxin transporter PIN1 and promoting its vacuolar degradation (Marhavý et al., 2011, 2014). This effect is independent of transcription and\r\ntranslation. Therefore, it suggests novel, non-canonical cytokinin activity occuring possibly on the posttranslational level. Impact of cytokinin and other plant hormones on auxin transporters (including PIN1) on the posttranslational level is described in detail in the introduction part of this thesis in a form of a review (Semeradova et al., 2020). To gain insights into the molecular machinery underlying cytokinin effect on the endomembrane trafficking in the plant cell, in particular on the PIN1 degradation, we conducted two large proteomic screens: 1) Identification of cytokinin binding proteins using\r\nchemical proteomics. 2) Monitoring of proteomic and phosphoproteomic changes upon cytokinin treatment. In the first screen, we identified DYNAMIN RELATED PROTEIN 2A (DRP2A). We found that DRP2A plays a role in cytokinin regulated processes during the plant growth and that cytokinin treatment promotes destabilization of DRP2A protein. However, the role of DRP2A in the PIN1 degradation remains to be elucidated. In the second screen, we found VACUOLAR PROTEIN SORTING 9A (VPS9A). VPS9a plays crucial role in plant’s response to cytokin and in cytokinin mediated PIN1 degradation. Altogether, we identified proteins, which bind to cytokinin and proteins that in response to\r\ncytokinin exhibit significantly changed abundance or phosphorylation pattern. By combining information from these two screens, we can pave our way towards understanding of noncanonical cytokinin effects."}],"oa":1,"file":[{"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_updated":"2022-12-20T23:30:05Z","file_size":28508629,"file_id":"10186","embargo_to":"open_access","file_name":"Hana_Semeradova_Disertation_Thesis_II_Revised_3.docx","checksum":"ce7108853e6cec6224f17cd6429b51fe","access_level":"closed","creator":"cziletti","relation":"source_file","date_created":"2021-10-27T07:45:37Z"},{"relation":"main_file","creator":"cziletti","date_created":"2021-10-27T07:45:57Z","file_size":10623525,"date_updated":"2022-12-20T23:30:05Z","content_type":"application/pdf","access_level":"open_access","embargo":"2022-10-28","checksum":"0d7afb846e8e31ec794de47bf44e12ef","file_name":"Hana_Semeradova_Disertation_Thesis_II_Revised_3PDFA.pdf","file_id":"10187"}],"doi":"10.15479/at:ista:10135","date_published":"2021-10-13T00:00:00Z","language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","year":"2021","month":"10","_id":"10135","OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","citation":{"ieee":"H. Semerádová, “Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis,” Institute of Science and Technology Austria, 2021.","ama":"Semerádová H. Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:10135\">10.15479/at:ista:10135</a>","apa":"Semerádová, H. (2021). <i>Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:10135\">https://doi.org/10.15479/at:ista:10135</a>","mla":"Semerádová, Hana. <i>Molecular Mechanisms of the Cytokinin-Regulated Endomembrane Trafficking to Coordinate Plant Organogenesis</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:10135\">10.15479/at:ista:10135</a>.","ista":"Semerádová H. 2021. Molecular mechanisms of the cytokinin-regulated endomembrane trafficking to coordinate plant organogenesis. Institute of Science and Technology Austria.","chicago":"Semerádová, Hana. “Molecular Mechanisms of the Cytokinin-Regulated Endomembrane Trafficking to Coordinate Plant Organogenesis.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:10135\">https://doi.org/10.15479/at:ista:10135</a>.","short":"H. Semerádová, Molecular Mechanisms of the Cytokinin-Regulated Endomembrane Trafficking to Coordinate Plant Organogenesis, Institute of Science and Technology Austria, 2021."},"supervisor":[{"orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","full_name":"Benková, Eva","last_name":"Benková"}],"publication_status":"published","type":"dissertation","corr_author":"1","degree_awarded":"PhD"},{"_id":"9438","pmid":1,"month":"06","scopus_import":"1","publication_status":"published","citation":{"ista":"Vandael DH, Okamoto Y, Borges Merjane C, Vargas Barroso VM, Suter B, Jonas PM. 2021. Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. Nature Protocols. 16(6), 2947–2967.","mla":"Vandael, David H., et al. “Subcellular Patch-Clamp Techniques for Single-Bouton Stimulation and Simultaneous Pre- and Postsynaptic Recording at Cortical Synapses.” <i>Nature Protocols</i>, vol. 16, no. 6, Springer Nature, 2021, pp. 2947–2967, doi:<a href=\"https://doi.org/10.1038/s41596-021-00526-0\">10.1038/s41596-021-00526-0</a>.","chicago":"Vandael, David H, Yuji Okamoto, Carolina Borges Merjane, Victor M Vargas Barroso, Benjamin Suter, and Peter M Jonas. “Subcellular Patch-Clamp Techniques for Single-Bouton Stimulation and Simultaneous Pre- and Postsynaptic Recording at Cortical Synapses.” <i>Nature Protocols</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41596-021-00526-0\">https://doi.org/10.1038/s41596-021-00526-0</a>.","short":"D.H. Vandael, Y. Okamoto, C. Borges Merjane, V.M. Vargas Barroso, B. Suter, P.M. Jonas, Nature Protocols 16 (2021) 2947–2967.","apa":"Vandael, D. H., Okamoto, Y., Borges Merjane, C., Vargas Barroso, V. M., Suter, B., &#38; Jonas, P. M. (2021). Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. <i>Nature Protocols</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41596-021-00526-0\">https://doi.org/10.1038/s41596-021-00526-0</a>","ama":"Vandael DH, Okamoto Y, Borges Merjane C, Vargas Barroso VM, Suter B, Jonas PM. Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses. <i>Nature Protocols</i>. 2021;16(6):2947–2967. doi:<a href=\"https://doi.org/10.1038/s41596-021-00526-0\">10.1038/s41596-021-00526-0</a>","ieee":"D. H. Vandael, Y. Okamoto, C. Borges Merjane, V. M. Vargas Barroso, B. Suter, and P. M. Jonas, “Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses,” <i>Nature Protocols</i>, vol. 16, no. 6. Springer Nature, pp. 2947–2967, 2021."},"volume":16,"corr_author":"1","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","file":[{"file_name":"VandaeletalAuthorVersion2021.pdf","access_level":"open_access","embargo":"2021-12-01","checksum":"7eb580abd8893cdb0b410cf41bc8c263","file_id":"9639","file_size":38574802,"content_type":"application/pdf","date_updated":"2021-12-02T23:30:05Z","date_created":"2021-07-08T12:27:55Z","relation":"main_file","creator":"cziletti"}],"oa":1,"date_published":"2021-06-01T00:00:00Z","language":[{"iso":"eng"}],"publisher":"Springer Nature","doi":"10.1038/s41596-021-00526-0","issue":"6","quality_controlled":"1","year":"2021","external_id":{"pmid":["33990799"],"isi":["000650528700003"]},"page":"2947–2967","isi":1,"has_accepted_license":"1","department":[{"_id":"PeJo"}],"project":[{"_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"692692","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse"},{"name":"Synaptic communication in neuronal microcircuits","call_identifier":"FWF","grant_number":"Z00312","_id":"25C5A090-B435-11E9-9278-68D0E5697425"},{"_id":"2696E7FE-B435-11E9-9278-68D0E5697425","grant_number":"V00739","call_identifier":"FWF","name":"Structural plasticity at mossy fiber-CA3 synapses"}],"title":"Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses","ddc":["570"],"day":"01","oa_version":"Submitted Version","intvolume":"        16","date_updated":"2025-04-22T22:30:43Z","abstract":[{"text":"Rigorous investigation of synaptic transmission requires analysis of unitary synaptic events by simultaneous recording from presynaptic terminals and postsynaptic target neurons. However, this has been achieved at only a limited number of model synapses, including the squid giant synapse and the mammalian calyx of Held. Cortical presynaptic terminals have been largely inaccessible to direct presynaptic recording, due to their small size. Here, we describe a protocol for improved subcellular patch-clamp recording in rat and mouse brain slices, with the synapse in a largely intact environment. Slice preparation takes ~2 h, recording ~3 h and post hoc morphological analysis 2 d. Single presynaptic hippocampal mossy fiber terminals are stimulated minimally invasively in the bouton-attached configuration, in which the cytoplasmic content remains unperturbed, or in the whole-bouton configuration, in which the cytoplasmic composition can be precisely controlled. Paired pre–postsynaptic recordings can be integrated with biocytin labeling and morphological analysis, allowing correlative investigation of synapse structure and function. Paired recordings can be obtained from mossy fiber terminals in slices from both rats and mice, implying applicability to genetically modified synapses. Paired recordings can also be performed together with axon tract stimulation or optogenetic activation, allowing comparison of unitary and compound synaptic events in the same target cell. Finally, paired recordings can be combined with spontaneous event analysis, permitting collection of miniature events generated at a single identified synapse. In conclusion, the subcellular patch-clamp techniques detailed here should facilitate analysis of biophysics, plasticity and circuit function of cortical synapses in the mammalian central nervous system.","lang":"eng"}],"author":[{"first_name":"David H","id":"3AE48E0A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7577-1676","last_name":"Vandael","full_name":"Vandael, David H"},{"last_name":"Okamoto","full_name":"Okamoto, Yuji","first_name":"Yuji","id":"3337E116-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0408-6094"},{"full_name":"Borges Merjane, Carolina","last_name":"Borges Merjane","orcid":"0000-0003-0005-401X","id":"4305C450-F248-11E8-B48F-1D18A9856A87","first_name":"Carolina"},{"first_name":"Victor M","id":"2F55A9DE-F248-11E8-B48F-1D18A9856A87","last_name":"Vargas Barroso","full_name":"Vargas Barroso, Victor M"},{"id":"4952F31E-F248-11E8-B48F-1D18A9856A87","first_name":"Benjamin","orcid":"0000-0002-9885-6936","last_name":"Suter","full_name":"Suter, Benjamin"},{"last_name":"Jonas","full_name":"Jonas, Peter M","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804"}],"article_processing_charge":"No","date_created":"2021-05-30T22:01:24Z","status":"public","file_date_updated":"2021-12-02T23:30:05Z","acknowledgement":"This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 692692 to P.J.) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award to P.J., V 739-B27 to C.B.M.). We are grateful to F. Marr and C. Altmutter for excellent technical assistance and cell reconstruction, E. Kralli-Beller for manuscript editing, and the Scientific Service Units of IST Austria, especially T. Asenov and Miba machine shop, for maximally efficient support.","publication":"Nature Protocols","acknowledged_ssus":[{"_id":"M-Shop"}],"ec_funded":1,"publication_identifier":{"issn":["1754-2189"],"eissn":["1750-2799"]}},{"month":"07","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"_id":"9623","OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publication_status":"published","citation":{"short":"S. Caballero Mancebo, Fertilization-Induced Deformations Are Controlled by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes, Institute of Science and Technology Austria, 2021.","ista":"Caballero Mancebo S. 2021. Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes. Institute of Science and Technology Austria.","chicago":"Caballero Mancebo, Silvia. “Fertilization-Induced Deformations Are Controlled by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes.” Institute of Science and Technology Austria, 2021. <a href=\"https://doi.org/10.15479/at:ista:9623\">https://doi.org/10.15479/at:ista:9623</a>.","mla":"Caballero Mancebo, Silvia. <i>Fertilization-Induced Deformations Are Controlled by the Actin Cortex and a Mitochondria-Rich Subcortical Layer in Ascidian Oocytes</i>. Institute of Science and Technology Austria, 2021, doi:<a href=\"https://doi.org/10.15479/at:ista:9623\">10.15479/at:ista:9623</a>.","ama":"Caballero Mancebo S. Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes. 2021. doi:<a href=\"https://doi.org/10.15479/at:ista:9623\">10.15479/at:ista:9623</a>","apa":"Caballero Mancebo, S. (2021). <i>Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:9623\">https://doi.org/10.15479/at:ista:9623</a>","ieee":"S. Caballero Mancebo, “Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes,” Institute of Science and Technology Austria, 2021."},"supervisor":[{"first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0912-4566","last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J"}],"degree_awarded":"PhD","type":"dissertation","corr_author":"1","file":[{"access_level":"closed","checksum":"e039225a47ef32666d59bf35ddd30ecf","embargo_to":"open_access","file_name":"PhDThesis_SCM.docx","file_id":"9624","file_size":131946790,"date_updated":"2022-07-02T22:30:06Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_created":"2021-07-01T14:48:54Z","relation":"source_file","creator":"scaballe"},{"file_id":"9625","file_name":"PhDThesis_SCM.pdf","checksum":"dd4d78962ea94ad95e97ca7d9af08f4b","access_level":"open_access","embargo":"2022-07-01","content_type":"application/pdf","date_updated":"2022-07-02T22:30:06Z","file_size":17094958,"date_created":"2021-07-01T14:46:25Z","creator":"scaballe","relation":"main_file"}],"oa":1,"doi":"10.15479/at:ista:9623","language":[{"iso":"eng"}],"date_published":"2021-07-01T00:00:00Z","publisher":"Institute of Science and Technology Austria","page":"111","year":"2021","title":"Fertilization-induced deformations are controlled by the actin cortex and a mitochondria-rich subcortical layer in ascidian oocytes","ddc":["570"],"alternative_title":["ISTA Thesis"],"has_accepted_license":"1","department":[{"_id":"GradSch"},{"_id":"CaHe"}],"author":[{"orcid":"0000-0002-5223-3346","first_name":"Silvia","id":"2F1E1758-F248-11E8-B48F-1D18A9856A87","full_name":"Caballero Mancebo, Silvia","last_name":"Caballero Mancebo"}],"oa_version":"Published Version","date_updated":"2026-06-18T19:38:50Z","abstract":[{"lang":"eng","text":"Cytoplasmic reorganizations are essential for morphogenesis. In large cells like oocytes, these reorganizations become crucial in patterning the oocyte for later stages of embryonic development. Ascidians oocytes reorganize their cytoplasm (ooplasm) in a spectacular manner. Ooplasmic reorganization is initiated at fertilization with the contraction of the actomyosin cortex along the animal-vegetal axis of the oocyte, driving the accumulation of cortical endoplasmic reticulum (cER), maternal mRNAs associated to it and a mitochondria-rich subcortical layer – the myoplasm – in a region of the vegetal pole termed contraction pole (CP). Here we have used the species Phallusia mammillata to investigate the changes in cell shape that accompany these reorganizations and the mechanochemical mechanisms underlining CP formation.\r\nWe report that the length of the animal-vegetal (AV) axis oscillates upon fertilization: it first undergoes a cycle of fast elongation-lengthening followed by a slow expansion of mainly the vegetal pole (VP) of the cell. We show that the fast oscillation corresponds to a dynamic polarization of the actin cortex as a result of a fertilization-induced increase in cortical tension in the oocyte that triggers a rupture of the cortex at the animal pole and the establishment of vegetal-directed cortical flows. These flows are responsible for the vegetal accumulation of actin causing the VP to flatten. \r\nWe find that the slow expansion of the VP, leading to CP formation, correlates with a relaxation of the vegetal cortex and that the myoplasm plays a role in the expansion. We show that the myoplasm is a solid-like layer that buckles under compression forces arising from the contracting actin cortex at the VP. Straightening of the myoplasm when actin flows stops, facilitates the expansion of the VP and the CP. Altogether, our results present a previously unrecognized role for the myoplasm in ascidian ooplasmic segregation. \r\n"}],"date_created":"2021-07-01T14:50:17Z","status":"public","file_date_updated":"2022-07-02T22:30:06Z","article_processing_charge":"No","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-012-1"]},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"NanoFab"},{"_id":"M-Shop"}],"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"9750"},{"id":"9006","relation":"part_of_dissertation","status":"public"}]}},{"isi":1,"place":"Cham","title":"Witness maps and applications","day":"29","date_updated":"2026-04-16T10:21:31Z","intvolume":"     12110","oa_version":"Preprint","abstract":[{"lang":"eng","text":"We introduce the notion of Witness Maps as a cryptographic notion of a proof system. A Unique Witness Map (UWM) deterministically maps all witnesses for an   NP  statement to a single representative witness, resulting in a computationally sound, deterministic-prover, non-interactive witness independent proof system. A relaxation of UWM, called Compact Witness Map (CWM), maps all the witnesses to a small number of witnesses, resulting in a “lossy” deterministic-prover, non-interactive proof-system. We also define a Dual Mode Witness Map (DMWM) which adds an “extractable” mode to a CWM.\r\nOur main construction is a DMWM for all   NP  relations, assuming sub-exponentially secure indistinguishability obfuscation (  iO ), along with standard cryptographic assumptions. The DMWM construction relies on a CWM and a new primitive called Cumulative All-Lossy-But-One Trapdoor Functions (C-ALBO-TDF), both of which are in turn instantiated based on   iO  and other primitives. Our instantiation of a CWM is in fact a UWM; in turn, we show that a UWM implies Witness Encryption. Along the way to constructing UWM and C-ALBO-TDF, we also construct, from standard assumptions, Puncturable Digital Signatures and a new primitive called Cumulative Lossy Trapdoor Functions (C-LTDF). The former improves up on a construction of Bellare et al. (Eurocrypt 2016), who relied on sub-exponentially secure   iO  and sub-exponentially secure OWF.\r\nAs an application of our constructions, we show how to use a DMWM to construct the first leakage and tamper-resilient signatures with a deterministic signer, thereby solving a decade old open problem posed by Katz and Vaikunthanathan (Asiacrypt 2009), by Boyle, Segev and Wichs (Eurocrypt 2011), as well as by Faonio and Venturi (Asiacrypt 2016). Our construction achieves the optimal leakage rate of   1−o(1) ."}],"author":[{"first_name":"Suvradip","id":"B9CD0494-D033-11E9-B219-A439E6697425","full_name":"Chakraborty, Suvradip","last_name":"Chakraborty"},{"first_name":"Manoj","full_name":"Prabhakaran, Manoj","last_name":"Prabhakaran"},{"first_name":"Daniel","full_name":"Wichs, Daniel","last_name":"Wichs"}],"article_processing_charge":"No","status":"public","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2020/090"}],"date_created":"2022-03-18T11:35:51Z","acknowledgement":"We would like to thank the anonymous reviewers of PKC 2019 for their useful comments and suggestions. We thank Omer Paneth for pointing out to us the connection between Unique Witness Maps (UWM) and Witness encryption (WE). The first author would like to acknowledge Pandu Rangan for his involvement during the initial discussion phase of the project.","publication":"Public-Key Cryptography","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783030453732"],"issn":["0302-9743"],"eisbn":["9783030453749"]},"_id":"10865","scopus_import":"1","month":"04","citation":{"ieee":"S. Chakraborty, M. Prabhakaran, and D. Wichs, “Witness maps and applications,” in <i>Public-Key Cryptography</i>, vol. 12110, A. Kiayias, Ed. Cham: Springer Nature, 2020, pp. 220–246.","apa":"Chakraborty, S., Prabhakaran, M., &#38; Wichs, D. (2020). Witness maps and applications. In A. Kiayias (Ed.), <i>Public-Key Cryptography</i> (Vol. 12110, pp. 220–246). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">https://doi.org/10.1007/978-3-030-45374-9_8</a>","ama":"Chakraborty S, Prabhakaran M, Wichs D. Witness maps and applications. In: Kiayias A, ed. <i>Public-Key Cryptography</i>. Vol 12110. LNCS. Cham: Springer Nature; 2020:220-246. doi:<a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">10.1007/978-3-030-45374-9_8</a>","short":"S. Chakraborty, M. Prabhakaran, D. Wichs, in:, A. Kiayias (Ed.), Public-Key Cryptography, Springer Nature, Cham, 2020, pp. 220–246.","ista":"Chakraborty S, Prabhakaran M, Wichs D. 2020.Witness maps and applications. In: Public-Key Cryptography. vol. 12110, 220–246.","mla":"Chakraborty, Suvradip, et al. “Witness Maps and Applications.” <i>Public-Key Cryptography</i>, edited by A Kiayias, vol. 12110, Springer Nature, 2020, pp. 220–46, doi:<a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">10.1007/978-3-030-45374-9_8</a>.","chicago":"Chakraborty, Suvradip, Manoj Prabhakaran, and Daniel Wichs. “Witness Maps and Applications.” In <i>Public-Key Cryptography</i>, edited by A Kiayias, 12110:220–46. LNCS. Cham: Springer Nature, 2020. <a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">https://doi.org/10.1007/978-3-030-45374-9_8</a>."},"publication_status":"published","volume":12110,"type":"book_chapter","corr_author":"1","editor":[{"full_name":"Kiayias, A","last_name":"Kiayias","first_name":"A"}],"series_title":"LNCS","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa":1,"doi":"10.1007/978-3-030-45374-9_8","publisher":"Springer Nature","language":[{"iso":"eng"}],"date_published":"2020-04-29T00:00:00Z","year":"2020","quality_controlled":"1","external_id":{"isi":["001299210200008"]},"page":"220-246"},{"acknowledgement":"We thank Margherita Talia, Stéphane Charlot, Adele Plat and Alba Vidal-García for helpful discussions. This work is supported by the ERC advanced grant 339659-MUSICOS (R. Bacon). AF acknowledges the support from grant PRIN MIUR 2017 20173ML3WW. MVM and JP would like to thank the Leiden/ESA Astrophysics Program for Summer Students (LEAPS) for funding at the outset of this project. FL, HK, and AV acknowledge support from the ERC starting grant ERC-757258-TRIPLE. TH was supported by Leading Initiative for Excellent Young Researchers, MEXT, Japan. JB acknowledges support by FCT/MCTES through national funds by the grant UID/FIS/04434/2019, UIDB/04434/2020 and UIDP/04434/2020 and through the Investigador FCT Contract No. IF/01654/2014/CP1215/CT0003. HI acknowledges support from JSPS KAKENHI Grant Number JP19K23462. We would also like to thank the organizers and participants of the Leiden Lorentz Center workshop: Revolutionary Spectroscopy of Today as a Springboard to Webb. This work made use of several open source python packages: NUMPY (van der Walt et al. 2011), MATPLOTLIB (Hunter 2007), ASTROPY (Astropy Collaboration 2013) and MPDAF (MUSE Python Data Analysis Framework, Piqueras et al. 2019).","date_created":"2022-07-06T09:38:16Z","main_file_link":[{"url":"https://arxiv.org/abs/2007.01878","open_access":"1"}],"status":"public","article_processing_charge":"No","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"publication":"Astronomy & Astrophysics","day":"18","title":"The MUSE Hubble Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα emitters at z > 3","author":[{"first_name":"Anna","full_name":"Feltre, Anna","last_name":"Feltre"},{"first_name":"Michael V.","full_name":"Maseda, Michael V.","last_name":"Maseda"},{"last_name":"Bacon","full_name":"Bacon, Roland","first_name":"Roland"},{"first_name":"Jayadev","last_name":"Pradeep","full_name":"Pradeep, Jayadev"},{"full_name":"Leclercq, Floriane","last_name":"Leclercq","first_name":"Floriane"},{"last_name":"Kusakabe","full_name":"Kusakabe, Haruka","first_name":"Haruka"},{"first_name":"Lutz","last_name":"Wisotzki","full_name":"Wisotzki, Lutz"},{"first_name":"Takuya","last_name":"Hashimoto","full_name":"Hashimoto, Takuya"},{"last_name":"Schmidt","full_name":"Schmidt, Kasper B.","first_name":"Kasper B."},{"first_name":"Jeremy","full_name":"Blaizot, Jeremy","last_name":"Blaizot"},{"full_name":"Brinchmann, Jarle","last_name":"Brinchmann","first_name":"Jarle"},{"first_name":"Leindert","full_name":"Boogaard, Leindert","last_name":"Boogaard"},{"last_name":"Cantalupo","full_name":"Cantalupo, Sebastiano","first_name":"Sebastiano"},{"last_name":"Carton","full_name":"Carton, David","first_name":"David"},{"first_name":"Hanae","last_name":"Inami","full_name":"Inami, Hanae"},{"first_name":"Wolfram","full_name":"Kollatschny, Wolfram","last_name":"Kollatschny"},{"first_name":"Raffaella A.","full_name":"Marino, Raffaella A.","last_name":"Marino"},{"first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X","last_name":"Matthee","full_name":"Matthee, Jorryt J"},{"last_name":"Nanayakkara","full_name":"Nanayakkara, Themiya","first_name":"Themiya"},{"last_name":"Richard","full_name":"Richard, Johan","first_name":"Johan"},{"first_name":"Joop","last_name":"Schaye","full_name":"Schaye, Joop"},{"first_name":"Laurence","last_name":"Tresse","full_name":"Tresse, Laurence"},{"first_name":"Tanya","last_name":"Urrutia","full_name":"Urrutia, Tanya"},{"last_name":"Verhamme","full_name":"Verhamme, Anne","first_name":"Anne"},{"first_name":"Peter M.","full_name":"Weilbacher, Peter M.","last_name":"Weilbacher"}],"abstract":[{"text":"We investigated the ultraviolet (UV) spectral properties of faint Lyman-α emitters (LAEs) in the redshift range 2.9 ≤ z ≤ 4.6, and we provide material to prepare future observations of the faint Universe. We used data from the MUSE Hubble Ultra Deep Survey to construct mean rest-frame spectra of continuum-faint (median MUV of −18 and down to MUV of −16), low stellar mass (median value of 108.4 M⊙ and down to 107 M⊙) LAEs at redshift z ≳ 3. We computed various averaged spectra of LAEs, subsampled on the basis of their observational (e.g., Lyα strength, UV magnitude and spectral slope) and physical (e.g., stellar mass and star-formation rate) properties. We searched for UV spectral features other than Lyα, such as higher ionization nebular emission lines and absorption features. We successfully observed the O III]λ1666 and [C III]λ1907+C III]λ1909 collisionally excited emission lines and the He IIλ1640 recombination feature, as well as the resonant C IVλλ1548,1551 doublet either in emission or P-Cygni. We compared the observed spectral properties of the different mean spectra and find the emission lines to vary with the observational and physical properties of the LAEs. In particular, the mean spectra of LAEs with larger Lyα equivalent widths, fainter UV magnitudes, bluer UV spectral slopes, and lower stellar masses show the strongest nebular emission. The line ratios of these lines are similar to those measured in the spectra of local metal-poor galaxies, while their equivalent widths are weaker compared to the handful of extreme values detected in individual spectra of z >  2 galaxies. This suggests that weak UV features are likely ubiquitous in high z, low-mass, and faint LAEs. We publicly released the stacked spectra, as they can serve as empirical templates for the design of future observations, such as those with the James Webb Space Telescope and the Extremely Large Telescope.","lang":"eng"}],"article_number":"A118","oa_version":"Published Version","intvolume":"       641","date_updated":"2022-07-19T09:35:43Z","date_published":"2020-09-18T00:00:00Z","doi":"10.1051/0004-6361/202038133","publisher":"EDP Sciences","language":[{"iso":"eng"}],"oa":1,"keyword":["Space and Planetary Science","Astronomy and Astrophysics","galaxies: evolution / galaxies: high-redshift / ISM: lines and bands / ultraviolet: ISM / ultraviolet: galaxies"],"article_type":"original","extern":"1","external_id":{"arxiv":["2007.01878"]},"quality_controlled":"1","year":"2020","scopus_import":"1","month":"09","arxiv":1,"_id":"11501","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":641,"type":"journal_article","publication_status":"published","citation":{"ieee":"A. Feltre <i>et al.</i>, “The MUSE Hubble Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα emitters at z &#62; 3,” <i>Astronomy &#38; Astrophysics</i>, vol. 641. EDP Sciences, 2020.","apa":"Feltre, A., Maseda, M. V., Bacon, R., Pradeep, J., Leclercq, F., Kusakabe, H., … Weilbacher, P. M. (2020). The MUSE Hubble Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα emitters at z &#62; 3. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202038133\">https://doi.org/10.1051/0004-6361/202038133</a>","ama":"Feltre A, Maseda MV, Bacon R, et al. The MUSE Hubble Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα emitters at z &#62; 3. <i>Astronomy &#38; Astrophysics</i>. 2020;641. doi:<a href=\"https://doi.org/10.1051/0004-6361/202038133\">10.1051/0004-6361/202038133</a>","mla":"Feltre, Anna, et al. “The MUSE Hubble Ultra Deep Field Survey: XV. The Mean Rest-UV Spectra of Lyα Emitters at z &#62; 3.” <i>Astronomy &#38; Astrophysics</i>, vol. 641, A118, EDP Sciences, 2020, doi:<a href=\"https://doi.org/10.1051/0004-6361/202038133\">10.1051/0004-6361/202038133</a>.","chicago":"Feltre, Anna, Michael V. Maseda, Roland Bacon, Jayadev Pradeep, Floriane Leclercq, Haruka Kusakabe, Lutz Wisotzki, et al. “The MUSE Hubble Ultra Deep Field Survey: XV. The Mean Rest-UV Spectra of Lyα Emitters at z &#62; 3.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2020. <a href=\"https://doi.org/10.1051/0004-6361/202038133\">https://doi.org/10.1051/0004-6361/202038133</a>.","ista":"Feltre A, Maseda MV, Bacon R, Pradeep J, Leclercq F, Kusakabe H, Wisotzki L, Hashimoto T, Schmidt KB, Blaizot J, Brinchmann J, Boogaard L, Cantalupo S, Carton D, Inami H, Kollatschny W, Marino RA, Matthee JJ, Nanayakkara T, Richard J, Schaye J, Tresse L, Urrutia T, Verhamme A, Weilbacher PM. 2020. The MUSE Hubble Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα emitters at z &#62; 3. Astronomy &#38; Astrophysics. 641, A118.","short":"A. Feltre, M.V. Maseda, R. Bacon, J. Pradeep, F. Leclercq, H. Kusakabe, L. Wisotzki, T. Hashimoto, K.B. Schmidt, J. Blaizot, J. Brinchmann, L. Boogaard, S. Cantalupo, D. Carton, H. Inami, W. Kollatschny, R.A. Marino, J.J. Matthee, T. Nanayakkara, J. Richard, J. Schaye, L. Tresse, T. Urrutia, A. Verhamme, P.M. Weilbacher, Astronomy &#38; Astrophysics 641 (2020)."}},{"abstract":[{"text":"Context. The Lyα emitter (LAE) fraction, XLAE, is a potentially powerful probe of the evolution of the intergalactic neutral hydrogen gas fraction. However, uncertainties in the measurement of XLAE are still under debate.\r\nAims. Thanks to deep data obtained with the integral field spectrograph Multi Unit Spectroscopic Explorer (MUSE), we can measure the evolution of the LAE fraction homogeneously over a wide redshift range of z ≈ 3–6 for UV-faint galaxies (down to UV magnitudes of M1500 ≈ −17.75). This is a significantly fainter range than in former studies (M1500 ≤ −18.75) and it allows us to probe the bulk of the population of high-redshift star-forming galaxies.\r\nMethods. We constructed a UV-complete photometric-redshift sample following UV luminosity functions and measured the Lyα emission with MUSE using the latest (second) data release from the MUSE Hubble Ultra Deep Field Survey.\r\nResults. We derived the redshift evolution of XLAE for M1500 ∈ [ − 21.75; −17.75] for the first time with a equivalent width range EW(Lyα) ≥ 65 Å and found low values of XLAE ≲ 30% at z ≲ 6. The best-fit linear relation is XLAE = 0.07+0.06−0.03z − 0.22+0.12−0.24. For M1500 ∈ [ − 20.25; −18.75] and EW(Lyα) ≥ 25 Å, our XLAE values are consistent with those in the literature within 1σ at z ≲ 5, but our median values are systematically lower than reported values over the whole redshift range. In addition, we do not find a significant dependence of XLAE on M1500 for EW(Lyα) ≥ 50 Å at z ≈ 3–4, in contrast with previous work. The differences in XLAE mainly arise from selection biases for Lyman Break Galaxies (LBGs) in the literature: UV-faint LBGs are more easily selected if they have strong Lyα emission, hence XLAE is biased towards higher values when those samples are used.\r\nConclusions. Our results suggest either a lower increase of XLAE towards z ≈ 6 than previously suggested, or even a turnover of XLAE at z ≈ 5.5, which may be the signature of a late or patchy reionization process. We compared our results with predictions from a cosmological galaxy evolution model. We find that a model with a bursty star formation (SF) can reproduce our observed LAE fractions much better than models where SF is a smooth function of time.","lang":"eng"}],"article_number":"A12","oa_version":"Published Version","intvolume":"       638","date_updated":"2022-07-19T09:35:20Z","author":[{"last_name":"Kusakabe","full_name":"Kusakabe, Haruka","first_name":"Haruka"},{"first_name":"Jérémy","full_name":"Blaizot, Jérémy","last_name":"Blaizot"},{"first_name":"Thibault","full_name":"Garel, Thibault","last_name":"Garel"},{"first_name":"Anne","last_name":"Verhamme","full_name":"Verhamme, Anne"},{"first_name":"Roland","full_name":"Bacon, Roland","last_name":"Bacon"},{"full_name":"Richard, Johan","last_name":"Richard","first_name":"Johan"},{"first_name":"Takuya","last_name":"Hashimoto","full_name":"Hashimoto, Takuya"},{"last_name":"Inami","full_name":"Inami, Hanae","first_name":"Hanae"},{"full_name":"Conseil, Simon","last_name":"Conseil","first_name":"Simon"},{"first_name":"Bruno","last_name":"Guiderdoni","full_name":"Guiderdoni, Bruno"},{"full_name":"Drake, Alyssa B.","last_name":"Drake","first_name":"Alyssa B."},{"full_name":"Christian Herenz, Edmund","last_name":"Christian Herenz","first_name":"Edmund"},{"full_name":"Schaye, Joop","last_name":"Schaye","first_name":"Joop"},{"first_name":"Pascal","last_name":"Oesch","full_name":"Oesch, Pascal"},{"last_name":"Matthee","full_name":"Matthee, Jorryt J","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X"},{"first_name":"Raffaella","last_name":"Anna Marino","full_name":"Anna Marino, Raffaella"},{"first_name":"Kasper","last_name":"Borello Schmidt","full_name":"Borello Schmidt, Kasper"},{"last_name":"Pelló","full_name":"Pelló, Roser","first_name":"Roser"},{"first_name":"Michael","full_name":"Maseda, Michael","last_name":"Maseda"},{"full_name":"Leclercq, Floriane","last_name":"Leclercq","first_name":"Floriane"},{"first_name":"Josephine","last_name":"Kerutt","full_name":"Kerutt, Josephine"},{"full_name":"Mahler, Guillaume","last_name":"Mahler","first_name":"Guillaume"}],"day":"03","title":"The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6","publication":"Astronomy & Astrophysics","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"article_processing_charge":"No","acknowledgement":"We thank the anonymous referee for constructive comments and suggestions. We would like to express our gratitude to Stephane De Barros and Pablo Arrabal Haro for kindly providing their data plotted in Figs. 1, 2, and 8. We are grateful to Kazuhiro Shimasaku, Masami Ouchi, Rieko Momose, Daniel Schaerer, Hidenobu Yajima, Taku Okamura, Makoto Ando, and Hinako Goto for giving insightful comments and suggestions. This work is based on observations taken by VLT, which is operated by European Southern Observatory. This research made use of Astropy (http://www.astropy.org), which is a community-developed core Python package for Astronomy (Astropy Collaboration 2013, 2018), MARZ, MPDAF, and matplotlib (Hunter 2007). H.K. acknowledges support from Japan Society for the Promotion of Science (JSPS) through the JSPS Research Fellowship for Young Scientists and Overseas Challenge Program for Young Researchers. AV acknowledges support from the ERC starting grant 757258-TRIPLE and the SNF Professorship 176808-TRIPLE. This work was supported by the project FOGHAR (Agence Nationale de la Recherche, ANR-13-BS05-0010-02). JB acknowledges support from the ORAGE project from the Agence Nationale de la Recherche under grant ANR-14-CE33-0016-03. JR acknowledges support from the ERC starting grant 336736-CALENDS. T. H. acknowledges supports by the Grant-inAid for Scientic Research 19J01620.","date_created":"2022-07-06T09:50:48Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2003.12083"}],"status":"public","type":"journal_article","volume":638,"publication_status":"published","citation":{"short":"H. Kusakabe, J. Blaizot, T. Garel, A. Verhamme, R. Bacon, J. Richard, T. Hashimoto, H. Inami, S. Conseil, B. Guiderdoni, A.B. Drake, E. Christian Herenz, J. Schaye, P. Oesch, J.J. Matthee, R. Anna Marino, K. Borello Schmidt, R. Pelló, M. Maseda, F. Leclercq, J. Kerutt, G. Mahler, Astronomy &#38; Astrophysics 638 (2020).","chicago":"Kusakabe, Haruka, Jérémy Blaizot, Thibault Garel, Anne Verhamme, Roland Bacon, Johan Richard, Takuya Hashimoto, et al. “The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα Emitter Fraction from z = 3 to z = 6.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2020. <a href=\"https://doi.org/10.1051/0004-6361/201937340\">https://doi.org/10.1051/0004-6361/201937340</a>.","ista":"Kusakabe H, Blaizot J, Garel T, Verhamme A, Bacon R, Richard J, Hashimoto T, Inami H, Conseil S, Guiderdoni B, Drake AB, Christian Herenz E, Schaye J, Oesch P, Matthee JJ, Anna Marino R, Borello Schmidt K, Pelló R, Maseda M, Leclercq F, Kerutt J, Mahler G. 2020. The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6. Astronomy &#38; Astrophysics. 638, A12.","mla":"Kusakabe, Haruka, et al. “The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα Emitter Fraction from z = 3 to z = 6.” <i>Astronomy &#38; Astrophysics</i>, vol. 638, A12, EDP Sciences, 2020, doi:<a href=\"https://doi.org/10.1051/0004-6361/201937340\">10.1051/0004-6361/201937340</a>.","ama":"Kusakabe H, Blaizot J, Garel T, et al. The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6. <i>Astronomy &#38; Astrophysics</i>. 2020;638. doi:<a href=\"https://doi.org/10.1051/0004-6361/201937340\">10.1051/0004-6361/201937340</a>","apa":"Kusakabe, H., Blaizot, J., Garel, T., Verhamme, A., Bacon, R., Richard, J., … Mahler, G. (2020). The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/201937340\">https://doi.org/10.1051/0004-6361/201937340</a>","ieee":"H. Kusakabe <i>et al.</i>, “The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6,” <i>Astronomy &#38; Astrophysics</i>, vol. 638. EDP Sciences, 2020."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"11503","scopus_import":"1","month":"06","arxiv":1,"quality_controlled":"1","year":"2020","external_id":{"arxiv":["2003.12083"]},"keyword":["Space and Planetary Science","Astronomy and Astrophysics","dark ages / reionization / first stars / early Universe / cosmology: observations / galaxies: evolution / galaxies: high-redshift / intergalactic medium"],"article_type":"original","extern":"1","publisher":"EDP Sciences","date_published":"2020-06-03T00:00:00Z","doi":"10.1051/0004-6361/201937340","language":[{"iso":"eng"}],"oa":1},{"title":"The MUSE Hubble Ultra Deep field survey: XIII. Spatially resolved spectral properties of Lyman α haloes around star-forming galaxies at z > 3","day":"11","author":[{"first_name":"Floriane","full_name":"Leclercq, Floriane","last_name":"Leclercq"},{"first_name":"Roland","full_name":"Bacon, Roland","last_name":"Bacon"},{"full_name":"Verhamme, Anne","last_name":"Verhamme","first_name":"Anne"},{"first_name":"Thibault","full_name":"Garel, Thibault","last_name":"Garel"},{"last_name":"Blaizot","full_name":"Blaizot, Jérémy","first_name":"Jérémy"},{"first_name":"Jarle","last_name":"Brinchmann","full_name":"Brinchmann, Jarle"},{"full_name":"Cantalupo, Sebastiano","last_name":"Cantalupo","first_name":"Sebastiano"},{"first_name":"Adélaïde","last_name":"Claeyssens","full_name":"Claeyssens, Adélaïde"},{"first_name":"Simon","last_name":"Conseil","full_name":"Conseil, Simon"},{"full_name":"Contini, Thierry","last_name":"Contini","first_name":"Thierry"},{"first_name":"Takuya","full_name":"Hashimoto, Takuya","last_name":"Hashimoto"},{"last_name":"Herenz","full_name":"Herenz, Edmund Christian","first_name":"Edmund Christian"},{"full_name":"Kusakabe, Haruka","last_name":"Kusakabe","first_name":"Haruka"},{"full_name":"Marino, Raffaella Anna","last_name":"Marino","first_name":"Raffaella Anna"},{"last_name":"Maseda","full_name":"Maseda, Michael","first_name":"Michael"},{"last_name":"Matthee","full_name":"Matthee, Jorryt J","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X"},{"first_name":"Peter","full_name":"Mitchell, Peter","last_name":"Mitchell"},{"last_name":"Pezzulli","full_name":"Pezzulli, Gabriele","first_name":"Gabriele"},{"last_name":"Richard","full_name":"Richard, Johan","first_name":"Johan"},{"last_name":"Schmidt","full_name":"Schmidt, Kasper Borello","first_name":"Kasper Borello"},{"first_name":"Lutz","full_name":"Wisotzki, Lutz","last_name":"Wisotzki"}],"date_updated":"2022-07-19T09:36:58Z","intvolume":"       635","oa_version":"Published Version","article_number":"A82","abstract":[{"text":"We present spatially resolved maps of six individually-detected Lyman α haloes (LAHs) as well as a first statistical analysis of the Lyman α (Lyα) spectral signature in the circum-galactic medium of high-redshift star-forming galaxies (−17.5 >  MUV >  −21.5) using the Multi-Unit Spectroscopic Explorer. Our resolved spectroscopic analysis of the LAHs reveals significant intrahalo variations of the Lyα line profile. Using a three-dimensional two-component model for the Lyα emission, we measured the full width at half maximum (FWHM), the peak velocity shift, and the asymmetry of the Lyα line in the core and in the halo of 19 galaxies. We find that the Lyα line shape is statistically different in the halo compared to the core (in terms of width, peak wavelength, and asymmetry) for ≈40% of our galaxies. Similarly to object-by-object based studies and a recent resolved study using lensing, we find a correlation between the peak velocity shift and the width of the Lyα line both at the interstellar and circum-galactic scales. This trend has been predicted by radiative transfer simulations of galactic winds as a result of resonant scattering in outflows. While there is a lack of correlation between the spectral properties and the spatial scale lengths of our LAHs, we find a correlation between the width of the line in the LAH and the halo flux fraction. Interestingly, UV bright galaxies (MUV <  −20) show broader, more redshifted, and less asymmetric Lyα lines in their haloes. The most significant correlation found is for the FWHM of the line and the UV continuum slope of the galaxy, suggesting that the redder galaxies have broader Lyα lines. The generally broad and red line shapes found in the halo component suggest that the Lyα haloes are powered either by scattering processes through an outflowing medium, fluorescent emission from outflowing cold clumps of gas, or a mix of both. Considering the large diversity of the Lyα line profiles observed in our sample and the lack of strong correlation, the interpretation of our results is still broadly open and underlines the need for realistic spatially resolved models of the LAHs.","lang":"eng"}],"status":"public","date_created":"2022-07-06T09:56:20Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2002.05731"}],"acknowledgement":"F.L., R.B., and S.C. acknowledge support from the ERC advanced grant 339659-MUSICOS. F.L., T.G., H.K., and A.V. acknowledge support from the ERC starting grant ERC-757258-TRIPLE. A.C. and J.R. acknowledge support from the ERC starting grant 336736-CALENDS. J.B. acknowledges support by FCT/MCTES through national funds (PID-DAC) by grant UID/FIS/04434/2019 and through Investigador FCT Contract No.IF/01654/2014/CP1215/CT0003. T.H. was supported by Leading Initiative for Excellent Young Researchers, MEXT, Japan.","article_processing_charge":"No","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"publication":"Astronomy & Astrophysics","arxiv":1,"month":"03","scopus_import":"1","_id":"11504","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ieee":"F. Leclercq <i>et al.</i>, “The MUSE Hubble Ultra Deep field survey: XIII. Spatially resolved spectral properties of Lyman α haloes around star-forming galaxies at z &#62; 3,” <i>Astronomy &#38; Astrophysics</i>, vol. 635. EDP Sciences, 2020.","ama":"Leclercq F, Bacon R, Verhamme A, et al. The MUSE Hubble Ultra Deep field survey: XIII. Spatially resolved spectral properties of Lyman α haloes around star-forming galaxies at z &#62; 3. <i>Astronomy &#38; Astrophysics</i>. 2020;635. doi:<a href=\"https://doi.org/10.1051/0004-6361/201937339\">10.1051/0004-6361/201937339</a>","apa":"Leclercq, F., Bacon, R., Verhamme, A., Garel, T., Blaizot, J., Brinchmann, J., … Wisotzki, L. (2020). The MUSE Hubble Ultra Deep field survey: XIII. Spatially resolved spectral properties of Lyman α haloes around star-forming galaxies at z &#62; 3. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/201937339\">https://doi.org/10.1051/0004-6361/201937339</a>","ista":"Leclercq F, Bacon R, Verhamme A, Garel T, Blaizot J, Brinchmann J, Cantalupo S, Claeyssens A, Conseil S, Contini T, Hashimoto T, Herenz EC, Kusakabe H, Marino RA, Maseda M, Matthee JJ, Mitchell P, Pezzulli G, Richard J, Schmidt KB, Wisotzki L. 2020. The MUSE Hubble Ultra Deep field survey: XIII. Spatially resolved spectral properties of Lyman α haloes around star-forming galaxies at z &#62; 3. Astronomy &#38; Astrophysics. 635, A82.","mla":"Leclercq, Floriane, et al. “The MUSE Hubble Ultra Deep Field Survey: XIII. Spatially Resolved Spectral Properties of Lyman α Haloes around Star-Forming Galaxies at z &#62; 3.” <i>Astronomy &#38; Astrophysics</i>, vol. 635, A82, EDP Sciences, 2020, doi:<a href=\"https://doi.org/10.1051/0004-6361/201937339\">10.1051/0004-6361/201937339</a>.","chicago":"Leclercq, Floriane, Roland Bacon, Anne Verhamme, Thibault Garel, Jérémy Blaizot, Jarle Brinchmann, Sebastiano Cantalupo, et al. “The MUSE Hubble Ultra Deep Field Survey: XIII. Spatially Resolved Spectral Properties of Lyman α Haloes around Star-Forming Galaxies at z &#62; 3.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2020. <a href=\"https://doi.org/10.1051/0004-6361/201937339\">https://doi.org/10.1051/0004-6361/201937339</a>.","short":"F. Leclercq, R. Bacon, A. Verhamme, T. Garel, J. Blaizot, J. Brinchmann, S. Cantalupo, A. Claeyssens, S. Conseil, T. Contini, T. Hashimoto, E.C. Herenz, H. Kusakabe, R.A. Marino, M. Maseda, J.J. Matthee, P. Mitchell, G. Pezzulli, J. Richard, K.B. Schmidt, L. Wisotzki, Astronomy &#38; Astrophysics 635 (2020)."},"publication_status":"published","volume":635,"type":"journal_article","oa":1,"date_published":"2020-03-11T00:00:00Z","publisher":"EDP Sciences","language":[{"iso":"eng"}],"doi":"10.1051/0004-6361/201937339","extern":"1","article_type":"original","keyword":["Space and Planetary Science","Astronomy and Astrophysics galaxies: high-redshift / galaxies: formation / galaxies: evolution / cosmology: observations"],"external_id":{"arxiv":["2002.05731"]},"year":"2020","quality_controlled":"1"},{"article_processing_charge":"No","acknowledgement":"We are thankful to the anonymous referee for useful comments and suggestions that improved the quality of this paper. B.D. acknowledges financial support from NASA through the Astrophysics Data Analysis Program (ADAP), grant number NNX12AE20G, and the National Science Foundation, grant number 1716907. B.D. is thankful to Andreas Faisst, Laura Danly, and Matthew Burlando for their companionship during the observing run. B.D. is grateful to the COSMOS team for their useful comments during the team meeting in New York City 2019 May 14–17. A.R. research was made possible by Friends of W. M. Keck Observatory who philanthropically support the Keck Science Collaborative (KSC) fund. The observations presented herein were obtained at the W. M. Keck Observatory (program C236, PI Scoville), which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. The authors would like to recognize and acknowledge the very prominent cultural role and reverence that the summit of Maunakea has always had within the indigenous Hawaiian community. We are fortunate to have the opportunity to perform observations from this mountain.","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2002.06207"}],"date_created":"2022-07-06T13:10:51Z","status":"public","publication":"The Astrophysical Journal","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"day":"19","title":"Spectroscopic confirmation of a coma cluster progenitor at z ∼ 2.2","abstract":[{"text":"We report the spectroscopic confirmation of a new protocluster in the COSMOS field at z ∼ 2.2, COSMOS Cluster 2.2 (CC2.2), originally identified as an overdensity of narrowband selected Hα emitting candidates. With only two masks of Keck/MOSFIRE near-IR spectroscopy in both H (∼1.47–1.81 μm) and K (∼1.92–2.40 μm) bands (∼1.5 hr each), we confirm 35 unique protocluster members with at least two emission lines detected with S/N > 3. Combined with 12 extra members from the zCOSMOS-deep spectroscopic survey (47 in total), we estimate a mean redshift and a line-of-sight velocity dispersion of zmean = 2.23224 ± 0.00101 and σlos = 645 ± 69 km s−1 for this protocluster, respectively. Assuming virialization and spherical symmetry for the system, we estimate a total mass of Mvir ∼ (1–2) ×1014M⊙ for the structure. We evaluate a number density enhancement of δg ∼ 7 for this system and we argue that the structure is likely not fully virialized at z ∼ 2.2. However, in a spherical collapse model, δg is expected to grow to a linear matter enhancement of ∼1.9 by z = 0, exceeding the collapse threshold of 1.69, and leading to a fully collapsed and virialized Coma-type structure with a total mass of Mdyn(z = 0) ∼ 9.2 × 1014M⊙ by now. This observationally efficient confirmation suggests that large narrowband emission-line galaxy surveys, when combined with ancillary photometric data, can be used to effectively trace the large-scale structure and protoclusters at a time when they are mostly dominated by star-forming galaxies.","lang":"eng"}],"oa_version":"Preprint","article_number":"8","intvolume":"       892","date_updated":"2022-07-19T09:31:35Z","author":[{"last_name":"Darvish","full_name":"Darvish, Behnam","first_name":"Behnam"},{"first_name":"Nick Z.","last_name":"Scoville","full_name":"Scoville, Nick Z."},{"first_name":"Christopher","full_name":"Martin, Christopher","last_name":"Martin"},{"full_name":"Sobral, David","last_name":"Sobral","first_name":"David"},{"first_name":"Bahram","last_name":"Mobasher","full_name":"Mobasher, Bahram"},{"first_name":"Alessandro","last_name":"Rettura","full_name":"Rettura, Alessandro"},{"last_name":"Matthee","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","orcid":"0000-0003-2871-127X"},{"full_name":"Capak, Peter","last_name":"Capak","first_name":"Peter"},{"last_name":"Chartab","full_name":"Chartab, Nima","first_name":"Nima"},{"last_name":"Hemmati","full_name":"Hemmati, Shoubaneh","first_name":"Shoubaneh"},{"full_name":"Masters, Daniel","last_name":"Masters","first_name":"Daniel"},{"first_name":"Hooshang","last_name":"Nayyeri","full_name":"Nayyeri, Hooshang"},{"last_name":"O’Sullivan","full_name":"O’Sullivan, Donal","first_name":"Donal"},{"first_name":"Ana","full_name":"Paulino-Afonso, Ana","last_name":"Paulino-Afonso"},{"first_name":"Zahra","full_name":"Sattari, Zahra","last_name":"Sattari"},{"last_name":"Shahidi","full_name":"Shahidi, Abtin","first_name":"Abtin"},{"full_name":"Salvato, Mara","last_name":"Salvato","first_name":"Mara"},{"last_name":"Lemaux","full_name":"Lemaux, Brian C.","first_name":"Brian C."},{"first_name":"Olivier Le","last_name":"Fèvre","full_name":"Fèvre, Olivier Le"},{"first_name":"Olga","full_name":"Cucciati, Olga","last_name":"Cucciati"}],"keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"article_type":"original","extern":"1","language":[{"iso":"eng"}],"date_published":"2020-03-19T00:00:00Z","publisher":"IOP Publishing","doi":"10.3847/1538-4357/ab75c3","issue":"1","oa":1,"quality_controlled":"1","year":"2020","external_id":{"arxiv":["2002.06207"]},"_id":"11513","month":"03","scopus_import":"1","arxiv":1,"type":"journal_article","volume":892,"publication_status":"published","citation":{"short":"B. Darvish, N.Z. Scoville, C. Martin, D. Sobral, B. Mobasher, A. Rettura, J.J. Matthee, P. Capak, N. Chartab, S. Hemmati, D. Masters, H. Nayyeri, D. O’Sullivan, A. Paulino-Afonso, Z. Sattari, A. Shahidi, M. Salvato, B.C. Lemaux, O.L. Fèvre, O. Cucciati, The Astrophysical Journal 892 (2020).","ista":"Darvish B, Scoville NZ, Martin C, Sobral D, Mobasher B, Rettura A, Matthee JJ, Capak P, Chartab N, Hemmati S, Masters D, Nayyeri H, O’Sullivan D, Paulino-Afonso A, Sattari Z, Shahidi A, Salvato M, Lemaux BC, Fèvre OL, Cucciati O. 2020. Spectroscopic confirmation of a coma cluster progenitor at z ∼ 2.2. The Astrophysical Journal. 892(1), 8.","mla":"Darvish, Behnam, et al. “Spectroscopic Confirmation of a Coma Cluster Progenitor at z ∼ 2.2.” <i>The Astrophysical Journal</i>, vol. 892, no. 1, 8, IOP Publishing, 2020, doi:<a href=\"https://doi.org/10.3847/1538-4357/ab75c3\">10.3847/1538-4357/ab75c3</a>.","chicago":"Darvish, Behnam, Nick Z. Scoville, Christopher Martin, David Sobral, Bahram Mobasher, Alessandro Rettura, Jorryt J Matthee, et al. “Spectroscopic Confirmation of a Coma Cluster Progenitor at z ∼ 2.2.” <i>The Astrophysical Journal</i>. IOP Publishing, 2020. <a href=\"https://doi.org/10.3847/1538-4357/ab75c3\">https://doi.org/10.3847/1538-4357/ab75c3</a>.","ama":"Darvish B, Scoville NZ, Martin C, et al. Spectroscopic confirmation of a coma cluster progenitor at z ∼ 2.2. <i>The Astrophysical Journal</i>. 2020;892(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ab75c3\">10.3847/1538-4357/ab75c3</a>","apa":"Darvish, B., Scoville, N. Z., Martin, C., Sobral, D., Mobasher, B., Rettura, A., … Cucciati, O. (2020). Spectroscopic confirmation of a coma cluster progenitor at z ∼ 2.2. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ab75c3\">https://doi.org/10.3847/1538-4357/ab75c3</a>","ieee":"B. Darvish <i>et al.</i>, “Spectroscopic confirmation of a coma cluster progenitor at z ∼ 2.2,” <i>The Astrophysical Journal</i>, vol. 892, no. 1. IOP Publishing, 2020."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"abstract":[{"text":"A prediction of the classic active galactic nucleus (AGN) unification model is the presence of ionization cones with different orientations depending on the AGN type. Confirmations of this model exist for present times, but it is less clear in the early Universe. Here, we use the morphology of giant Ly α nebulae around AGNs at redshift z ∼ 3 to probe AGN emission and therefore the validity of the AGN unification model at this redshift. We compare the spatial morphology of 19 nebulae previously found around type I AGNs with a new sample of four Ly α nebulae detected around type II AGNs. Using two independent techniques, we find that nebulae around type II AGNs are more asymmetric than around type I, at least at radial distances r > 30 physical kpc (pkpc) from the ionizing source. We conclude that the type I and type II AGNs in our sample show evidence of different surrounding ionizing geometries. This suggests that the classical AGN unification model is also valid for high-redshift sources. Finally, we discuss how the lack of asymmetry in the inner parts (r ≲ 30 pkpc) and the associated high values of the He II to Ly α ratios in these regions could indicate additional sources of (hard) ionizing radiation originating within or in proximity of the AGN host galaxies. This work demonstrates that the morphologies of giant Ly α nebulae can be used to understand and study the geometry of high-redshift AGNs on circumnuclear scales and it lays the foundation for future studies using much larger statistical samples.","lang":"eng"}],"oa_version":"Preprint","intvolume":"       495","date_updated":"2022-08-18T11:17:47Z","author":[{"first_name":"J S","last_name":"den Brok","full_name":"den Brok, J S"},{"last_name":"Cantalupo","full_name":"Cantalupo, S","first_name":"S"},{"first_name":"R","full_name":"Mackenzie, R","last_name":"Mackenzie"},{"full_name":"Marino, R A","last_name":"Marino","first_name":"R A"},{"first_name":"G","last_name":"Pezzulli","full_name":"Pezzulli, G"},{"full_name":"Matthee, Jorryt J","last_name":"Matthee","orcid":"0000-0003-2871-127X","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720"},{"first_name":"S D","full_name":"Johnson, S D","last_name":"Johnson"},{"first_name":"M","last_name":"Krumpe","full_name":"Krumpe, M"},{"last_name":"Urrutia","full_name":"Urrutia, T","first_name":"T"},{"last_name":"Kollatschny","full_name":"Kollatschny, W","first_name":"W"}],"day":"01","title":"Probing the AGN unification model at redshift z ∼ 3 with MUSE observations of giant Lyα nebulae","publication":"Monthly Notices of the Royal Astronomical Society","publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"article_processing_charge":"No","acknowledgement":"SC and GP gratefully acknowledge support from Swiss National Science Foundation grant PP00P2 163824. MK acknowledges support by DLR500R1904.","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2005.01732"}],"date_created":"2022-07-07T10:40:17Z","status":"public","volume":495,"type":"journal_article","publication_status":"published","citation":{"ista":"den Brok JS, Cantalupo S, Mackenzie R, Marino RA, Pezzulli G, Matthee JJ, Johnson SD, Krumpe M, Urrutia T, Kollatschny W. 2020. Probing the AGN unification model at redshift z ∼ 3 with MUSE observations of giant Lyα nebulae. Monthly Notices of the Royal Astronomical Society. 495(2), 1874–1887.","chicago":"den Brok, J S, S Cantalupo, R Mackenzie, R A Marino, G Pezzulli, Jorryt J Matthee, S D Johnson, M Krumpe, T Urrutia, and W Kollatschny. “Probing the AGN Unification Model at Redshift z ∼ 3 with MUSE Observations of Giant Lyα Nebulae.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2020. <a href=\"https://doi.org/10.1093/mnras/staa1269\">https://doi.org/10.1093/mnras/staa1269</a>.","mla":"den Brok, J. S., et al. “Probing the AGN Unification Model at Redshift z ∼ 3 with MUSE Observations of Giant Lyα Nebulae.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 495, no. 2, Oxford University Press, 2020, pp. 1874–87, doi:<a href=\"https://doi.org/10.1093/mnras/staa1269\">10.1093/mnras/staa1269</a>.","short":"J.S. den Brok, S. Cantalupo, R. Mackenzie, R.A. Marino, G. Pezzulli, J.J. Matthee, S.D. Johnson, M. Krumpe, T. Urrutia, W. Kollatschny, Monthly Notices of the Royal Astronomical Society 495 (2020) 1874–1887.","ieee":"J. S. den Brok <i>et al.</i>, “Probing the AGN unification model at redshift z ∼ 3 with MUSE observations of giant Lyα nebulae,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 495, no. 2. Oxford University Press, pp. 1874–1887, 2020.","ama":"den Brok JS, Cantalupo S, Mackenzie R, et al. Probing the AGN unification model at redshift z ∼ 3 with MUSE observations of giant Lyα nebulae. <i>Monthly Notices of the Royal Astronomical Society</i>. 2020;495(2):1874-1887. doi:<a href=\"https://doi.org/10.1093/mnras/staa1269\">10.1093/mnras/staa1269</a>","apa":"den Brok, J. S., Cantalupo, S., Mackenzie, R., Marino, R. A., Pezzulli, G., Matthee, J. J., … Kollatschny, W. (2020). Probing the AGN unification model at redshift z ∼ 3 with MUSE observations of giant Lyα nebulae. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/staa1269\">https://doi.org/10.1093/mnras/staa1269</a>"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"11530","scopus_import":"1","month":"06","arxiv":1,"quality_controlled":"1","year":"2020","page":"1874-1887","external_id":{"arxiv":["2005.01732"]},"keyword":["Space and Planetary Science","Astronomy and Astrophysics","galaxies: active","galaxies: high-redshift","intergalactic medium","quasars: emission lines","quasars: general"],"article_type":"original","extern":"1","publisher":"Oxford University Press","date_published":"2020-06-01T00:00:00Z","doi":"10.1093/mnras/staa1269","language":[{"iso":"eng"}],"issue":"2","oa":1},{"page":"5120-5130","external_id":{"arxiv":["2002.11117"]},"quality_controlled":"1","year":"2020","date_published":"2020-04-01T00:00:00Z","doi":"10.1093/mnras/staa622","publisher":"Oxford University Press","language":[{"iso":"eng"}],"issue":"4","oa":1,"keyword":["Space and Planetary Science","Astronomy and Astrophysics","Galaxies: evolution","Galaxies: high-redshift","Galaxies: ISM"],"article_type":"original","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","volume":493,"publication_status":"published","citation":{"mla":"Maseda, Michael V., et al. “Elevated Ionizing Photon Production Efficiency in Faint High-Equivalent-Width Lyman-α Emitters.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 493, no. 4, Oxford University Press, 2020, pp. 5120–30, doi:<a href=\"https://doi.org/10.1093/mnras/staa622\">10.1093/mnras/staa622</a>.","chicago":"Maseda, Michael V, Roland Bacon, Daniel Lam, Jorryt J Matthee, Jarle Brinchmann, Joop Schaye, Ivo Labbe, et al. “Elevated Ionizing Photon Production Efficiency in Faint High-Equivalent-Width Lyman-α Emitters.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2020. <a href=\"https://doi.org/10.1093/mnras/staa622\">https://doi.org/10.1093/mnras/staa622</a>.","ista":"Maseda MV, Bacon R, Lam D, Matthee JJ, Brinchmann J, Schaye J, Labbe I, Schmidt KB, Boogaard L, Bouwens R, Cantalupo S, Franx M, Hashimoto T, Inami H, Kusakabe H, Mahler G, Nanayakkara T, Richard J, Wisotzki L. 2020. Elevated ionizing photon production efficiency in faint high-equivalent-width Lyman-α emitters. Monthly Notices of the Royal Astronomical Society. 493(4), 5120–5130.","short":"M.V. Maseda, R. Bacon, D. Lam, J.J. Matthee, J. Brinchmann, J. Schaye, I. Labbe, K.B. Schmidt, L. Boogaard, R. Bouwens, S. Cantalupo, M. Franx, T. Hashimoto, H. Inami, H. Kusakabe, G. Mahler, T. Nanayakkara, J. Richard, L. Wisotzki, Monthly Notices of the Royal Astronomical Society 493 (2020) 5120–5130.","ama":"Maseda MV, Bacon R, Lam D, et al. Elevated ionizing photon production efficiency in faint high-equivalent-width Lyman-α emitters. <i>Monthly Notices of the Royal Astronomical Society</i>. 2020;493(4):5120-5130. doi:<a href=\"https://doi.org/10.1093/mnras/staa622\">10.1093/mnras/staa622</a>","apa":"Maseda, M. V., Bacon, R., Lam, D., Matthee, J. J., Brinchmann, J., Schaye, J., … Wisotzki, L. (2020). Elevated ionizing photon production efficiency in faint high-equivalent-width Lyman-α emitters. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/staa622\">https://doi.org/10.1093/mnras/staa622</a>","ieee":"M. V. Maseda <i>et al.</i>, “Elevated ionizing photon production efficiency in faint high-equivalent-width Lyman-α emitters,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 493, no. 4. Oxford University Press, pp. 5120–5130, 2020."},"scopus_import":"1","month":"04","arxiv":1,"_id":"11531","publication_identifier":{"issn":["0035-8711"],"eissn":["1365-2966"]},"publication":"Monthly Notices of the Royal Astronomical Society","acknowledgement":"We would like to thank the anonymous referee for a thoughtful report and suggestions that have improved this manuscript. We are also grateful to everyone involved in the Spitzer Space Telescope mission and everyone at the Spitzer Science Center: we are truly fortunate to have been able to use data from this facility. J. B. acknowledges support by FCT/MCTES through national funds by this grant UID/FIS/04434/2019 and through the Investigador FCT contract no. IF/01654/2014/CP1215/CT0003. S. C. gratefully acknowledges support from Swiss National Science Foundation grant PP00P2 163824. We would also like to thank Mauro Stefanon for his assistance with de-blending the IRAC photometry, Pieter van Dokkum for a number of useful suggestions, and Daniel Schaerer for information regarding the stellar population models. This study is based on observations made with ESO telescopes at the La Silla Paranal Observatory under programs IDs 094.A-2089(B), 095.A0010(A), 096.A-0045(A), and 096.A-0045(B).","date_created":"2022-07-07T10:46:41Z","main_file_link":[{"url":"https://doi.org/10.1093/mnras/staa622","open_access":"1"}],"status":"public","article_processing_charge":"No","author":[{"last_name":"Maseda","full_name":"Maseda, Michael V","first_name":"Michael V"},{"last_name":"Bacon","full_name":"Bacon, Roland","first_name":"Roland"},{"first_name":"Daniel","full_name":"Lam, Daniel","last_name":"Lam"},{"last_name":"Matthee","full_name":"Matthee, Jorryt J","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X"},{"first_name":"Jarle","last_name":"Brinchmann","full_name":"Brinchmann, Jarle"},{"full_name":"Schaye, Joop","last_name":"Schaye","first_name":"Joop"},{"first_name":"Ivo","last_name":"Labbe","full_name":"Labbe, Ivo"},{"last_name":"Schmidt","full_name":"Schmidt, Kasper B","first_name":"Kasper B"},{"first_name":"Leindert","full_name":"Boogaard, Leindert","last_name":"Boogaard"},{"first_name":"Rychard","full_name":"Bouwens, Rychard","last_name":"Bouwens"},{"full_name":"Cantalupo, Sebastiano","last_name":"Cantalupo","first_name":"Sebastiano"},{"first_name":"Marijn","last_name":"Franx","full_name":"Franx, Marijn"},{"first_name":"Takuya","full_name":"Hashimoto, Takuya","last_name":"Hashimoto"},{"first_name":"Hanae","full_name":"Inami, Hanae","last_name":"Inami"},{"first_name":"Haruka","last_name":"Kusakabe","full_name":"Kusakabe, Haruka"},{"full_name":"Mahler, Guillaume","last_name":"Mahler","first_name":"Guillaume"},{"first_name":"Themiya","last_name":"Nanayakkara","full_name":"Nanayakkara, Themiya"},{"first_name":"Johan","full_name":"Richard, Johan","last_name":"Richard"},{"full_name":"Wisotzki, Lutz","last_name":"Wisotzki","first_name":"Lutz"}],"abstract":[{"text":"While low-luminosity galaxies dominate number counts at all redshifts, their contribution to cosmic reionization is poorly understood due to a lack of knowledge of their physical properties. We isolate a sample of 35 z ≈ 4–5 continuum-faint Lyman-α emitters from deep VLT/MUSE spectroscopy and directly measure their H α emission using stacked Spitzer/IRAC Ch. 1 photometry. Based on Hubble Space Telescope imaging, we determine that the average UV continuum magnitude is fainter than −16 (≈ 0.01 L⋆), implying a median Lyman-α equivalent width of 259 Å. By combining the H α measurement with the UV magnitude, we determine the ionizing photon production efficiency, ξion, a first for such faint galaxies. The measurement of log10 (ξion [Hz erg−1]) = 26.28 (⁠+0.28−0.40⁠) is in excess of literature measurements of both continuum- and emission line-selected samples, implying a more efficient production of ionizing photons in these lower luminosity, Lyman-α-selected systems. We conclude that this elevated efficiency can be explained by stellar populations with metallicities between 4 × 10−4 and 0.008, with light-weighted ages less than 3 Myr.","lang":"eng"}],"oa_version":"Published Version","date_updated":"2022-08-18T11:23:27Z","intvolume":"       493","day":"01","title":"Elevated ionizing photon production efficiency in faint high-equivalent-width Lyman-α emitters"},{"day":"01","title":"The evolution of rest-frame UV properties, Ly α EWs, and the SFR–stellar mass relation at z ∼ 2–6 for SC4K LAEs","abstract":[{"text":"We explore deep rest-frame UV to FIR data in the COSMOS field to measure the individual spectral energy distributions (SED) of the ∼4000 SC4K (Sobral et al.) Lyman α (Ly α) emitters (LAEs) at z ∼ 2–6. We find typical stellar masses of 109.3 ± 0.6 M⊙ and star formation rates (SFR) of SFRSED=4.4+10.5−2.4 M⊙ yr−1 and SFRLyα=5.9+6.3−2.6 M⊙ yr−1, combined with very blue UV slopes of β=−2.1+0.5−0.4⁠, but with significant variations within the population. MUV and β are correlated in a similar way to UV-selected sources, but LAEs are consistently bluer. This suggests that LAEs are the youngest and/or most dust-poor subset of the UV-selected population. We also study the Ly α rest-frame equivalent width (EW0) and find 45 ‘extreme’ LAEs with EW0 > 240 Å (3σ), implying a low number density of (7 ± 1) × 10−7 Mpc−3. Overall, we measure little to no evolution of the Ly α EW0 and scale length parameter (w0), which are consistently high (EW0=140+280−70 Å, w0=129+11−11 Å) from z ∼ 6 to z ∼ 2 and below. However, w0 is anticorrelated with MUV and stellar mass. Our results imply that sources selected as LAEs have a high Ly α escape fraction (fesc,Ly α) irrespective of cosmic time, but fesc,Ly α is still higher for UV-fainter and lower mass LAEs. The least massive LAEs (<109.5 M⊙) are typically located above the star formation ‘main sequence’ (MS), but the offset from the MS decreases towards z ∼ 6 and towards 1010 M⊙. Our results imply a lack of evolution in the properties of LAEs across time and reveals the increasing overlap in properties of LAEs and UV-continuum selected galaxies as typical star-forming galaxies at high redshift effectively become LAEs.","lang":"eng"}],"intvolume":"       493","date_updated":"2022-08-18T11:27:43Z","oa_version":"Preprint","author":[{"first_name":"S","full_name":"Santos, S","last_name":"Santos"},{"last_name":"Sobral","full_name":"Sobral, D","first_name":"D"},{"orcid":"0000-0003-2871-127X","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","last_name":"Matthee"},{"last_name":"Calhau","full_name":"Calhau, J","first_name":"J"},{"full_name":"da Cunha, E","last_name":"da Cunha","first_name":"E"},{"first_name":"B","last_name":"Ribeiro","full_name":"Ribeiro, B"},{"last_name":"Paulino-Afonso","full_name":"Paulino-Afonso, A","first_name":"A"},{"first_name":"P","last_name":"Arrabal Haro","full_name":"Arrabal Haro, P"},{"first_name":"J","full_name":"Butterworth, J","last_name":"Butterworth"}],"article_processing_charge":"No","acknowledgement":"We thank the anonymous referee for the valuable feedback that significantly improved the quality and clarity of this paper. SS and JC acknowledge studentships from Lancaster University. APA acknowledges support from Fundação para a Ciência e a Tecnologia through the project PTDC/FISAST/31546/2017. The authors would like to thank Ali Khostovan, Sara Perez Sanchez, Alex Bennett and Tom Rose for contributions and discussions in the early stages of this work. Based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under ESO programme ID 179.A-2005 and on data products produced by CALET and the Cambridge Astronomy Survey Unit on behalf of the UltraVISTA consortium. Finally, the authors acknowledge the unique value of the publicly available analysis software TOPCAT (Taylor 2005) and publicly available programming language Python, including the numpy, pyfits, matplotlib, scipy and astropy (Astropy Collaboration et al. 2013) packages. This work is based on the public SC4K sample of LAEs (Sobral et al. 2018a) and we release the full catalogue with all the photometry and properties derived in this paper, in electronic format, along with the relevant tables.","status":"public","date_created":"2022-07-07T12:05:23Z","main_file_link":[{"url":"https://arxiv.org/abs/1910.02959","open_access":"1"}],"publication":"Monthly Notices of the Royal Astronomical Society","publication_identifier":{"issn":["0035-8711"],"eissn":["1365-2966"]},"_id":"11533","month":"03","scopus_import":"1","arxiv":1,"type":"journal_article","volume":493,"citation":{"apa":"Santos, S., Sobral, D., Matthee, J. J., Calhau, J., da Cunha, E., Ribeiro, B., … Butterworth, J. (2020). The evolution of rest-frame UV properties, Ly α EWs, and the SFR–stellar mass relation at z ∼ 2–6 for SC4K LAEs. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/staa093\">https://doi.org/10.1093/mnras/staa093</a>","ama":"Santos S, Sobral D, Matthee JJ, et al. The evolution of rest-frame UV properties, Ly α EWs, and the SFR–stellar mass relation at z ∼ 2–6 for SC4K LAEs. <i>Monthly Notices of the Royal Astronomical Society</i>. 2020;493(1):141-160. doi:<a href=\"https://doi.org/10.1093/mnras/staa093\">10.1093/mnras/staa093</a>","ieee":"S. Santos <i>et al.</i>, “The evolution of rest-frame UV properties, Ly α EWs, and the SFR–stellar mass relation at z ∼ 2–6 for SC4K LAEs,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 493, no. 1. Oxford University Press, pp. 141–160, 2020.","ista":"Santos S, Sobral D, Matthee JJ, Calhau J, da Cunha E, Ribeiro B, Paulino-Afonso A, Arrabal Haro P, Butterworth J. 2020. The evolution of rest-frame UV properties, Ly α EWs, and the SFR–stellar mass relation at z ∼ 2–6 for SC4K LAEs. Monthly Notices of the Royal Astronomical Society. 493(1), 141–160.","chicago":"Santos, S, D Sobral, Jorryt J Matthee, J Calhau, E da Cunha, B Ribeiro, A Paulino-Afonso, P Arrabal Haro, and J Butterworth. “The Evolution of Rest-Frame UV Properties, Ly α EWs, and the SFR–Stellar Mass Relation at z ∼ 2–6 for SC4K LAEs.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2020. <a href=\"https://doi.org/10.1093/mnras/staa093\">https://doi.org/10.1093/mnras/staa093</a>.","mla":"Santos, S., et al. “The Evolution of Rest-Frame UV Properties, Ly α EWs, and the SFR–Stellar Mass Relation at z ∼ 2–6 for SC4K LAEs.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 493, no. 1, Oxford University Press, 2020, pp. 141–60, doi:<a href=\"https://doi.org/10.1093/mnras/staa093\">10.1093/mnras/staa093</a>.","short":"S. Santos, D. Sobral, J.J. Matthee, J. Calhau, E. da Cunha, B. Ribeiro, A. Paulino-Afonso, P. Arrabal Haro, J. Butterworth, Monthly Notices of the Royal Astronomical Society 493 (2020) 141–160."},"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Space and Planetary Science","Astronomy and Astrophysics","galaxies: evolution","galaxies: formation","galaxies: high-redshift","galaxies: star formation"],"extern":"1","article_type":"original","issue":"1","publisher":"Oxford University Press","language":[{"iso":"eng"}],"date_published":"2020-03-01T00:00:00Z","doi":"10.1093/mnras/staa093","oa":1,"year":"2020","quality_controlled":"1","page":"141-160","external_id":{"arxiv":["1910.02959"]}},{"publication_identifier":{"issn":["0035-8711"],"eissn":["1365-2966"]},"publication":"Monthly Notices of the Royal Astronomical Society","acknowledgement":"JM acknowledges the support of a Huygens PhD fellowship from Leiden University. We thank Camila Correa for help analysing snipshot merger trees. We thank the anonymous referee for constructive comments. We also thank Jarle Brinchmann, Rob Crain, Antonios Katsianis, Paola Popesso, and David Sobral for discussions and suggestions. We also thank the participants of the Lorentz Center workshop ‘A Decade of the Star-Forming Main Sequence’ held on 2017 September 4–8, for discussions and ideas. We have benefited from the public available programming language PYTHON, including the NUMPY, MATPLOTLIB, and SCIPY (Hunter 2007) packages and the TOPCAT analysis tool (Taylor 2013).","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1909.11672"}],"date_created":"2022-07-08T07:34:10Z","status":"public","article_processing_charge":"No","author":[{"last_name":"Calhau","full_name":"Calhau, João","first_name":"João"},{"first_name":"David","last_name":"Sobral","full_name":"Sobral, David"},{"first_name":"Sérgio","last_name":"Santos","full_name":"Santos, Sérgio"},{"last_name":"Matthee","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","orcid":"0000-0003-2871-127X"},{"first_name":"Ana","full_name":"Paulino-Afonso, Ana","last_name":"Paulino-Afonso"},{"full_name":"Stroe, Andra","last_name":"Stroe","first_name":"Andra"},{"first_name":"Brooke","last_name":"Simmons","full_name":"Simmons, Brooke"},{"full_name":"Barlow-Hall, Cassandra","last_name":"Barlow-Hall","first_name":"Cassandra"},{"full_name":"Adams, Benjamin","last_name":"Adams","first_name":"Benjamin"}],"abstract":[{"lang":"eng","text":"Despite recent progress in understanding Ly α emitters (LAEs), relatively little is known regarding their typical black hole activity across cosmic time. Here, we study the X-ray and radio properties of ∼4000 LAEs at 2.2 < z < 6 from the SC4K survey in the COSMOS field. We detect 254 (⁠6.8per cent±0.4per cent⁠) LAEs individually in the X-rays (S/N > 3) with an average luminosity of 1044.31±0.01ergs−1 and average black hole accretion rate (BHAR) of 0.72±0.01 M⊙ yr−1, consistent with moderate to high accreting active galactic neuclei (AGNs). We detect 120 sources in deep radio data (radio AGN fraction of 3.2per cent±0.3per cent⁠). The global AGN fraction (⁠8.6per cent±0.4per cent⁠) rises with Ly α luminosity and declines with increasing redshift. For X-ray-detected LAEs, Ly α luminosities correlate with the BHARs, suggesting that Ly α luminosity becomes a BHAR indicator. Most LAEs (⁠93.1per cent±0.6per cent⁠) at 2 < z < 6 have no detectable X-ray emission (BHARs < 0.017 M⊙ yr−1). The median star formation rate (SFR) of star-forming LAEs from Ly α and radio luminosities is 7.6+6.6−2.8 M⊙ yr−1. The black hole to galaxy growth ratio (BHAR/SFR) for LAEs is <0.0022, consistent with typical star-forming galaxies and the local BHAR/SFR relation. We conclude that LAEs at 2 < z < 6 include two different populations: an AGN population, where Ly α luminosity traces BHAR, and another with low SFRs which remain undetected in even the deepest X-ray stacks but is detected in the radio stacks."}],"oa_version":"Preprint","intvolume":"       493","date_updated":"2022-08-18T11:25:31Z","day":"01","title":"The X-ray and radio activity of typical and luminous Ly α emitters from z ∼ 2 to z ∼ 6: Evidence for a diverse, evolving population","page":"3341-3362","external_id":{"arxiv":["1909.11672"]},"quality_controlled":"1","year":"2020","language":[{"iso":"eng"}],"publisher":"Oxford University Press","doi":"10.1093/mnras/staa476","date_published":"2020-04-01T00:00:00Z","issue":"3","oa":1,"keyword":["Space and Planetary Science","Astronomy and Astrophysics","galaxies: active","galaxies: evolution","galaxies: high-redshift","quasars: supermassive black holes","galaxies: star formation","cosmology: observations","X-rays: galaxies"],"article_type":"original","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","volume":493,"publication_status":"published","citation":{"ieee":"J. Calhau <i>et al.</i>, “The X-ray and radio activity of typical and luminous Ly α emitters from z ∼ 2 to z ∼ 6: Evidence for a diverse, evolving population,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 493, no. 3. Oxford University Press, pp. 3341–3362, 2020.","ama":"Calhau J, Sobral D, Santos S, et al. The X-ray and radio activity of typical and luminous Ly α emitters from z ∼ 2 to z ∼ 6: Evidence for a diverse, evolving population. <i>Monthly Notices of the Royal Astronomical Society</i>. 2020;493(3):3341-3362. doi:<a href=\"https://doi.org/10.1093/mnras/staa476\">10.1093/mnras/staa476</a>","apa":"Calhau, J., Sobral, D., Santos, S., Matthee, J. J., Paulino-Afonso, A., Stroe, A., … Adams, B. (2020). The X-ray and radio activity of typical and luminous Ly α emitters from z ∼ 2 to z ∼ 6: Evidence for a diverse, evolving population. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/staa476\">https://doi.org/10.1093/mnras/staa476</a>","short":"J. Calhau, D. Sobral, S. Santos, J.J. Matthee, A. Paulino-Afonso, A. Stroe, B. Simmons, C. Barlow-Hall, B. Adams, Monthly Notices of the Royal Astronomical Society 493 (2020) 3341–3362.","chicago":"Calhau, João, David Sobral, Sérgio Santos, Jorryt J Matthee, Ana Paulino-Afonso, Andra Stroe, Brooke Simmons, Cassandra Barlow-Hall, and Benjamin Adams. “The X-Ray and Radio Activity of Typical and Luminous Ly α Emitters from z ∼ 2 to z ∼ 6: Evidence for a Diverse, Evolving Population.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2020. <a href=\"https://doi.org/10.1093/mnras/staa476\">https://doi.org/10.1093/mnras/staa476</a>.","ista":"Calhau J, Sobral D, Santos S, Matthee JJ, Paulino-Afonso A, Stroe A, Simmons B, Barlow-Hall C, Adams B. 2020. The X-ray and radio activity of typical and luminous Ly α emitters from z ∼ 2 to z ∼ 6: Evidence for a diverse, evolving population. Monthly Notices of the Royal Astronomical Society. 493(3), 3341–3362.","mla":"Calhau, João, et al. “The X-Ray and Radio Activity of Typical and Luminous Ly α Emitters from z ∼ 2 to z ∼ 6: Evidence for a Diverse, Evolving Population.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 493, no. 3, Oxford University Press, 2020, pp. 3341–62, doi:<a href=\"https://doi.org/10.1093/mnras/staa476\">10.1093/mnras/staa476</a>."},"scopus_import":"1","month":"04","arxiv":1,"_id":"11539"},{"place":"Cham","title":"The impact of a fossil magnetic field on dipolar mixed-mode frequencies in sub- and red-giant stars","day":"19","alternative_title":["Astrophysics and Space Science Proceedings"],"author":[{"orcid":"0000-0003-0142-4000","id":"d9edb345-f866-11ec-9b37-d119b5234501","first_name":"Lisa Annabelle","full_name":"Bugnet, Lisa Annabelle","last_name":"Bugnet"},{"full_name":"Prat, V.","last_name":"Prat","first_name":"V."},{"last_name":"Mathis","full_name":"Mathis, S.","first_name":"S."},{"first_name":"R. A.","last_name":"García","full_name":"García, R. A."},{"first_name":"S.","last_name":"Mathur","full_name":"Mathur, S."},{"first_name":"K.","last_name":"Augustson","full_name":"Augustson, K."},{"last_name":"Neiner","full_name":"Neiner, C.","first_name":"C."},{"first_name":"M. J.","full_name":"Thompson, M. J.","last_name":"Thompson"}],"date_updated":"2024-10-14T11:42:19Z","intvolume":"        57","oa_version":"Preprint","abstract":[{"text":"The recent discovery of low-amplitude dipolar oscillation mixed modes in massive red giants indicates the presence of a missing physical process inside their cores. Stars more massive than ∼ 1.3 M⊙ are known to develop a convective core during the main-sequence: the dynamo process triggered by this convection could be the origin of a strong magnetic field inside the core of the star, trapped when it becomes stably stratified and for the rest of its evolution. The presence of highly magnetized white dwarfs strengthens the hypothesis of buried fossil magnetic fields inside the core of evolved low-mass stars. If such a fossil field exists, it should affect the mixed modes of red giants as they are sensitive to processes affecting the deepest layers of these stars. The impact of a magnetic field on dipolar oscillations modes was one of Pr. Michael J. Thompson’s research topics during the 90s when preparing the helioseismic SoHO space mission. As the detection of gravity modes in the Sun is still controversial, the investigation of the solar oscillation modes did not provide any hint of the existence of a magnetic field in the solar radiative core. Today we have access to the core of evolved stars thanks to the asteroseismic observation of mixed modes from CoRoT, Kepler, K2 and TESS missions. The idea of applying and generalizing the work done for the Sun came from discussions with Pr. Michael Thompson in early 2018 before we lost him. Following the path we drew together, we theoretically investigate the effect of a stable axisymmetric mixed poloidal and toroidal magnetic field, aligned with the rotation axis of the star, on the mixed modes frequencies of a typical evolved low-mass star. This enables us to estimate the magnetic perturbations to the eigenfrequencies of mixed dipolar modes, depending on the magnetic field strength and the evolutionary state of the star. We conclude that strong magnetic fields of ∼ 1MG should perturb the mixed-mode frequency pattern enough for its effects to be detectable inside current asteroseismic data.","lang":"eng"}],"status":"public","date_created":"2022-07-19T08:25:41Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2012.08684"}],"acknowledgement":"The authors of this work acknowledge the support received from the PLATO CNES grant, the National Aeronautics and Space Administration under Grant NNX15AF13G, by the National Science Foundation grant AST-1411685, the Ramon y Cajal fellowship number RYC-2015-17697, the ERC SPIRE grant (647383), and the Fundation L’Oréal-Unesco-Académie des sciences.","article_processing_charge":"No","publication_identifier":{"eissn":["1570-6605"],"isbn":["978-3-030-55335-7"],"issn":["1570-6591"],"eisbn":["978-3-030-55336-4"]},"publication":"Dynamics of the Sun and Stars","arxiv":1,"month":"12","scopus_import":"1","_id":"11622","editor":[{"first_name":"Mario","full_name":"Monteiro, Mario","last_name":"Monteiro"},{"first_name":"Rafael A","full_name":"Garcia, Rafael A","last_name":"Garcia"},{"first_name":"Jorgen","full_name":"Christensen-Dalsgaard, Jorgen","last_name":"Christensen-Dalsgaard"},{"first_name":"Scott W","full_name":"McIntosh, Scott W","last_name":"McIntosh"}],"series_title":"ASSSP","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Bugnet, Lisa Annabelle, V. Prat, S. Mathis, R. A. García, S. Mathur, K. Augustson, C. Neiner, and M. J. Thompson. “The Impact of a Fossil Magnetic Field on Dipolar Mixed-Mode Frequencies in Sub- and Red-Giant Stars.” In <i>Dynamics of the Sun and Stars</i>, edited by Mario Monteiro, Rafael A Garcia, Jorgen Christensen-Dalsgaard, and Scott W McIntosh, 1st ed., 57:251–57. ASSSP. Cham: Springer Nature, 2020. <a href=\"https://doi.org/10.1007/978-3-030-55336-4_33\">https://doi.org/10.1007/978-3-030-55336-4_33</a>.","ista":"Bugnet LA, Prat V, Mathis S, García RA, Mathur S, Augustson K, Neiner C, Thompson MJ. 2020.The impact of a fossil magnetic field on dipolar mixed-mode frequencies in sub- and red-giant stars. In: Dynamics of the Sun and Stars. Astrophysics and Space Science Proceedings, vol. 57, 251–257.","mla":"Bugnet, Lisa Annabelle, et al. “The Impact of a Fossil Magnetic Field on Dipolar Mixed-Mode Frequencies in Sub- and Red-Giant Stars.” <i>Dynamics of the Sun and Stars</i>, edited by Mario Monteiro et al., 1st ed., vol. 57, Springer Nature, 2020, pp. 251–57, doi:<a href=\"https://doi.org/10.1007/978-3-030-55336-4_33\">10.1007/978-3-030-55336-4_33</a>.","short":"L.A. Bugnet, V. Prat, S. Mathis, R.A. García, S. Mathur, K. Augustson, C. Neiner, M.J. Thompson, in:, M. Monteiro, R.A. Garcia, J. Christensen-Dalsgaard, S.W. McIntosh (Eds.), Dynamics of the Sun and Stars, 1st ed., Springer Nature, Cham, 2020, pp. 251–257.","ieee":"L. A. Bugnet <i>et al.</i>, “The impact of a fossil magnetic field on dipolar mixed-mode frequencies in sub- and red-giant stars,” in <i>Dynamics of the Sun and Stars</i>, 1st ed., vol. 57, M. Monteiro, R. A. Garcia, J. Christensen-Dalsgaard, and S. W. McIntosh, Eds. Cham: Springer Nature, 2020, pp. 251–257.","ama":"Bugnet LA, Prat V, Mathis S, et al. The impact of a fossil magnetic field on dipolar mixed-mode frequencies in sub- and red-giant stars. In: Monteiro M, Garcia RA, Christensen-Dalsgaard J, McIntosh SW, eds. <i>Dynamics of the Sun and Stars</i>. Vol 57. 1st ed. ASSSP. Cham: Springer Nature; 2020:251-257. doi:<a href=\"https://doi.org/10.1007/978-3-030-55336-4_33\">10.1007/978-3-030-55336-4_33</a>","apa":"Bugnet, L. A., Prat, V., Mathis, S., García, R. A., Mathur, S., Augustson, K., … Thompson, M. J. (2020). The impact of a fossil magnetic field on dipolar mixed-mode frequencies in sub- and red-giant stars. In M. Monteiro, R. A. Garcia, J. Christensen-Dalsgaard, &#38; S. W. McIntosh (Eds.), <i>Dynamics of the Sun and Stars</i> (1st ed., Vol. 57, pp. 251–257). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-55336-4_33\">https://doi.org/10.1007/978-3-030-55336-4_33</a>"},"publication_status":"published","edition":"1","type":"book_chapter","volume":57,"oa":1,"language":[{"iso":"eng"}],"date_published":"2020-12-19T00:00:00Z","doi":"10.1007/978-3-030-55336-4_33","publisher":"Springer Nature","extern":"1","external_id":{"arxiv":["2012.08684"]},"page":"251-257","year":"2020","quality_controlled":"1"},{"author":[{"last_name":"Chen","full_name":"Chen, Li","first_name":"Li"},{"first_name":"Gramoz","full_name":"Goranci, Gramoz","last_name":"Goranci"},{"orcid":"0000-0002-5008-6530","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H","full_name":"Henzinger, Monika H","last_name":"Henzinger"},{"last_name":"Peng","full_name":"Peng, Richard","first_name":"Richard"},{"full_name":"Saranurak, Thatchaphol","last_name":"Saranurak","first_name":"Thatchaphol"}],"abstract":[{"lang":"eng","text":"We present a general framework of designing efficient dynamic approximate algorithms for optimization problems on undirected graphs. In particular, we develop a technique that, given any problem that admits a certain notion of vertex sparsifiers, gives data structures that maintain approximate solutions in sub-linear update and query time. We illustrate the applicability of our paradigm to the following problems. (1)A fully-dynamic algorithm that approximates all-pair maximum-flows/minimum-cuts up to a nearly logarithmic factor in O~(n2/3) 11The O~(⋅) notation is used in this paper to hide poly-logarithmic factors. amortized time against an oblivious adversary, and O~(m3/4) time against an adaptive adversary. (2)An incremental data structure that maintains O(1) - approximate shortest path in no(1) time per operation, as well as fully dynamic approximate all-pair shortest path and transshipment in O~(n2/3+o(1)) amortized time per operation. (3)A fully-dynamic algorithm that approximates all-pair effective resistance up to an (1+ϵ) factor in O~(n2/3+o(1)ϵ−O(1)) amortized update time per operation. The key tool behind result (1) is the dynamic maintenance of an algorithmic construction due to Madry [FOCS' 10], which partitions a graph into a collection of simpler graph structures (known as j-trees) and approximately captures the cut-flow and metric structure of the graph. The O(1)-approximation guarantee of (2) is by adapting the distance oracles by [Thorup-Zwick JACM '05]. Result (3) is obtained by invoking the random-walk based spectral vertex sparsifier by [Durfee et al. STOC '19] in a hierarchical manner, while carefully keeping track of the recourse among levels in the hierarchy. See https://arxiv.org/pdf/2005.02368.pdf for the full version of this paper."}],"date_updated":"2024-11-06T12:17:53Z","oa_version":"Preprint","day":"01","title":"Fast dynamic cuts, distances and effective resistances via vertex sparsifiers","publication_identifier":{"eissn":["2575-8454"],"isbn":["978-1-7281-9622-0"],"eisbn":["978-1-7281-9621-3"]},"conference":{"location":"Durham, NC, United States","start_date":"2020-11-16","end_date":"2020-11-19","name":"FOCS: Annual Symposium on Foundations of Computer Science"},"publication":"61st Annual Symposium on Foundations of Computer Science","status":"public","main_file_link":[{"url":"https://arxiv.org/abs/2005.02368","open_access":"1"}],"date_created":"2022-08-16T07:33:12Z","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"conference","citation":{"ista":"Chen L, Goranci G, Henzinger M, Peng R, Saranurak T. 2020. Fast dynamic cuts, distances and effective resistances via vertex sparsifiers. 61st Annual Symposium on Foundations of Computer Science. FOCS: Annual Symposium on Foundations of Computer Science, 1135–1146.","mla":"Chen, Li, et al. “Fast Dynamic Cuts, Distances and Effective Resistances via Vertex Sparsifiers.” <i>61st Annual Symposium on Foundations of Computer Science</i>, Institute of Electrical and Electronics Engineers, 2020, pp. 1135–46, doi:<a href=\"https://doi.org/10.1109/focs46700.2020.00109\">10.1109/focs46700.2020.00109</a>.","chicago":"Chen, Li, Gramoz Goranci, Monika Henzinger, Richard Peng, and Thatchaphol Saranurak. “Fast Dynamic Cuts, Distances and Effective Resistances via Vertex Sparsifiers.” In <i>61st Annual Symposium on Foundations of Computer Science</i>, 1135–46. Institute of Electrical and Electronics Engineers, 2020. <a href=\"https://doi.org/10.1109/focs46700.2020.00109\">https://doi.org/10.1109/focs46700.2020.00109</a>.","short":"L. Chen, G. Goranci, M. Henzinger, R. Peng, T. Saranurak, in:, 61st Annual Symposium on Foundations of Computer Science, Institute of Electrical and Electronics Engineers, 2020, pp. 1135–1146.","apa":"Chen, L., Goranci, G., Henzinger, M., Peng, R., &#38; Saranurak, T. (2020). Fast dynamic cuts, distances and effective resistances via vertex sparsifiers. In <i>61st Annual Symposium on Foundations of Computer Science</i> (pp. 1135–1146). Durham, NC, United States: Institute of Electrical and Electronics Engineers. <a href=\"https://doi.org/10.1109/focs46700.2020.00109\">https://doi.org/10.1109/focs46700.2020.00109</a>","ama":"Chen L, Goranci G, Henzinger M, Peng R, Saranurak T. Fast dynamic cuts, distances and effective resistances via vertex sparsifiers. In: <i>61st Annual Symposium on Foundations of Computer Science</i>. Institute of Electrical and Electronics Engineers; 2020:1135-1146. doi:<a href=\"https://doi.org/10.1109/focs46700.2020.00109\">10.1109/focs46700.2020.00109</a>","ieee":"L. Chen, G. Goranci, M. Henzinger, R. Peng, and T. Saranurak, “Fast dynamic cuts, distances and effective resistances via vertex sparsifiers,” in <i>61st Annual Symposium on Foundations of Computer Science</i>, Durham, NC, United States, 2020, pp. 1135–1146."},"publication_status":"published","scopus_import":"1","month":"11","arxiv":1,"_id":"11852","page":"1135-1146","external_id":{"arxiv":["2005.02368"]},"year":"2020","quality_controlled":"1","doi":"10.1109/focs46700.2020.00109","language":[{"iso":"eng"}],"publisher":"Institute of Electrical and Electronics Engineers","date_published":"2020-11-01T00:00:00Z","oa":1,"extern":"1"},{"title":"Evidence for photocatalyst involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations","day":"24","author":[{"first_name":"Jamal A.","full_name":"Malik, Jamal A.","last_name":"Malik"},{"first_name":"Amiera","full_name":"Madani, Amiera","last_name":"Madani"},{"orcid":"0000-0001-8689-388X","first_name":"Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","full_name":"Pieber, Bartholomäus","last_name":"Pieber"},{"last_name":"Seeberger","full_name":"Seeberger, Peter H.","first_name":"Peter H."}],"date_updated":"2024-10-14T12:06:34Z","intvolume":"       142","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Dual photocatalysis and nickel catalysis can effect cross-coupling under mild conditions, but little is known about the in situ kinetics of this class of reactions. We report a comprehensive kinetic examination of a model carboxylate O-arylation, comparing a state-of-the-art homogeneous photocatalyst (Ir(ppy)3) with a competitive heterogeneous photocatalyst (graphitic carbon nitride). Experimental conditions were adjusted such that the nickel catalytic cycle is saturated with excited photocatalyst. This approach was designed to remove the role of the photocatalyst, by which only the intrinsic behaviors of the nickel catalytic cycles are observed. The two reactions did not display identical kinetics. Ir(ppy)3 deactivates the nickel catalytic cycle and creates more dehalogenated side product. Kinetic data for the reaction using Ir(ppy)3 supports a turnover-limiting reductive elimination. Graphitic carbon nitride gave higher selectivity, even at high photocatalyst-to-nickel ratios. The heterogeneous reaction also showed a rate dependence on aryl halide, indicating that oxidative addition plays a role in rate determination. The results argue against the current mechanistic hypothesis, which states that the photocatalyst is only involved to trigger reductive elimination."}],"status":"public","main_file_link":[{"url":"https://doi.org/10.1021/jacs.0c02848","open_access":"1"}],"date_created":"2022-08-25T10:57:38Z","article_processing_charge":"No","publication_identifier":{"eissn":["1520-5126"],"issn":["0002-7863"]},"publication":"Journal of the American Chemical Society","scopus_import":"1","month":"06","pmid":1,"_id":"11978","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ieee":"J. A. Malik, A. Madani, B. Pieber, and P. H. Seeberger, “Evidence for photocatalyst involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations,” <i>Journal of the American Chemical Society</i>, vol. 142, no. 25. American Chemical Society, pp. 11042–11049, 2020.","apa":"Malik, J. A., Madani, A., Pieber, B., &#38; Seeberger, P. H. (2020). Evidence for photocatalyst involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations. <i>Journal of the American Chemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.0c02848\">https://doi.org/10.1021/jacs.0c02848</a>","ama":"Malik JA, Madani A, Pieber B, Seeberger PH. Evidence for photocatalyst involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations. <i>Journal of the American Chemical Society</i>. 2020;142(25):11042-11049. doi:<a href=\"https://doi.org/10.1021/jacs.0c02848\">10.1021/jacs.0c02848</a>","mla":"Malik, Jamal A., et al. “Evidence for Photocatalyst Involvement in Oxidative Additions of Nickel-Catalyzed Carboxylate O-Arylations.” <i>Journal of the American Chemical Society</i>, vol. 142, no. 25, American Chemical Society, 2020, pp. 11042–49, doi:<a href=\"https://doi.org/10.1021/jacs.0c02848\">10.1021/jacs.0c02848</a>.","chicago":"Malik, Jamal A., Amiera Madani, Bartholomäus Pieber, and Peter H. Seeberger. “Evidence for Photocatalyst Involvement in Oxidative Additions of Nickel-Catalyzed Carboxylate O-Arylations.” <i>Journal of the American Chemical Society</i>. American Chemical Society, 2020. <a href=\"https://doi.org/10.1021/jacs.0c02848\">https://doi.org/10.1021/jacs.0c02848</a>.","ista":"Malik JA, Madani A, Pieber B, Seeberger PH. 2020. Evidence for photocatalyst involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations. Journal of the American Chemical Society. 142(25), 11042–11049.","short":"J.A. Malik, A. Madani, B. Pieber, P.H. Seeberger, Journal of the American Chemical Society 142 (2020) 11042–11049."},"publication_status":"published","type":"journal_article","volume":142,"oa":1,"issue":"25","date_published":"2020-06-24T00:00:00Z","publisher":"American Chemical Society","language":[{"iso":"eng"}],"doi":"10.1021/jacs.0c02848","extern":"1","article_type":"original","external_id":{"pmid":["32469219"]},"page":"11042-11049","year":"2020","quality_controlled":"1"},{"keyword":["Analytical Chemistry"],"article_type":"letter_note","extern":"1","doi":"10.1021/acs.analchem.0c02615","language":[{"iso":"eng"}],"date_published":"2020-10-16T00:00:00Z","publisher":"American Chemical Society","issue":"21","oa":1,"quality_controlled":"1","year":"2020","page":"14314-14318","external_id":{"pmid":["33063994"]},"_id":"12940","pmid":1,"month":"10","scopus_import":"1","type":"journal_article","volume":92,"publication_status":"published","citation":{"apa":"Meisenbichler, C., Kluibenschedl, F., &#38; Müller, T. (2020). A 3-in-1 hand-held ambient mass spectrometry interface for identification and 2D localization of chemicals on surfaces. <i>Analytical Chemistry</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.analchem.0c02615\">https://doi.org/10.1021/acs.analchem.0c02615</a>","ama":"Meisenbichler C, Kluibenschedl F, Müller T. A 3-in-1 hand-held ambient mass spectrometry interface for identification and 2D localization of chemicals on surfaces. <i>Analytical Chemistry</i>. 2020;92(21):14314-14318. doi:<a href=\"https://doi.org/10.1021/acs.analchem.0c02615\">10.1021/acs.analchem.0c02615</a>","ieee":"C. Meisenbichler, F. Kluibenschedl, and T. Müller, “A 3-in-1 hand-held ambient mass spectrometry interface for identification and 2D localization of chemicals on surfaces,” <i>Analytical Chemistry</i>, vol. 92, no. 21. American Chemical Society, pp. 14314–14318, 2020.","mla":"Meisenbichler, Christina, et al. “A 3-in-1 Hand-Held Ambient Mass Spectrometry Interface for Identification and 2D Localization of Chemicals on Surfaces.” <i>Analytical Chemistry</i>, vol. 92, no. 21, American Chemical Society, 2020, pp. 14314–18, doi:<a href=\"https://doi.org/10.1021/acs.analchem.0c02615\">10.1021/acs.analchem.0c02615</a>.","ista":"Meisenbichler C, Kluibenschedl F, Müller T. 2020. A 3-in-1 hand-held ambient mass spectrometry interface for identification and 2D localization of chemicals on surfaces. Analytical Chemistry. 92(21), 14314–14318.","chicago":"Meisenbichler, Christina, Florian Kluibenschedl, and Thomas Müller. “A 3-in-1 Hand-Held Ambient Mass Spectrometry Interface for Identification and 2D Localization of Chemicals on Surfaces.” <i>Analytical Chemistry</i>. American Chemical Society, 2020. <a href=\"https://doi.org/10.1021/acs.analchem.0c02615\">https://doi.org/10.1021/acs.analchem.0c02615</a>.","short":"C. Meisenbichler, F. Kluibenschedl, T. Müller, Analytical Chemistry 92 (2020) 14314–14318."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","date_created":"2023-05-10T14:50:19Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1021/acs.analchem.0c02615"}],"status":"public","publication":"Analytical Chemistry","publication_identifier":{"issn":["0003-2700","1520-6882"]},"day":"16","title":"A 3-in-1 hand-held ambient mass spectrometry interface for identification and 2D localization of chemicals on surfaces","abstract":[{"lang":"eng","text":"Desorption electrospray ionization (DESI), easy ambient sonic-spray ionization (EASI) and low-temperature plasma (LTP) ionization are powerful ambient ionization techniques for mass spectrometry. However, every single method has its limitation in terms of polarity and molecular weight of analyte molecules. After the miniaturization of every possible component of the different ion sources, we finally were able to embed two emitters and an ion transfer tubing into a small, hand-held device. The pen-like interface is connected to the mass spectrometer and a separate control unit via a bundle of flexible tubing and cables. The novel device allows the user to ionize an extended range of chemicals by simple switching between DESI, voltage-free EASI, or LTP ionization as well as to freely move the interface over a surface of interest. A mini camera, which is mounted on the tip of the pen, magnifies the desorption area and enables a simple positioning of the pen. The interface was successfully tested using different types of chemicals, pharmaceuticals, and real life samples. Moreover, the combination of optical data from the camera module and chemical data obtained by mass analysis facilitates a novel type of imaging mass spectrometry, which we name “interactive mass spectrometry imaging (IMSI)”."}],"oa_version":"Published Version","date_updated":"2023-05-15T08:01:20Z","intvolume":"        92","author":[{"last_name":"Meisenbichler","full_name":"Meisenbichler, Christina","first_name":"Christina"},{"id":"7499e70e-eb2c-11ec-b98b-f925648bc9d9","first_name":"Florian","full_name":"Kluibenschedl, Florian","last_name":"Kluibenschedl"},{"first_name":"Thomas","last_name":"Müller","full_name":"Müller, Thomas"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","volume":85,"type":"journal_article","citation":{"ieee":"X. Hu, P. K. Mandal, B. Kauffmann, and I. Huc, “Hybrid sequences that express both aromatic amide and α‐peptidic folding features,” <i>ChemPlusChem</i>, vol. 85, no. 7. Wiley, pp. 1580–1586, 2020.","ama":"Hu X, Mandal PK, Kauffmann B, Huc I. Hybrid sequences that express both aromatic amide and α‐peptidic folding features. <i>ChemPlusChem</i>. 2020;85(7):1580-1586. doi:<a href=\"https://doi.org/10.1002/cplu.202000416\">10.1002/cplu.202000416</a>","apa":"Hu, X., Mandal, P. K., Kauffmann, B., &#38; Huc, I. (2020). Hybrid sequences that express both aromatic amide and α‐peptidic folding features. <i>ChemPlusChem</i>. Wiley. <a href=\"https://doi.org/10.1002/cplu.202000416\">https://doi.org/10.1002/cplu.202000416</a>","short":"X. Hu, P.K. Mandal, B. Kauffmann, I. Huc, ChemPlusChem 85 (2020) 1580–1586.","chicago":"Hu, Xiaobo, Pradeep K Mandal, Brice Kauffmann, and Ivan Huc. “Hybrid Sequences That Express Both Aromatic Amide and Α‐peptidic Folding Features.” <i>ChemPlusChem</i>. Wiley, 2020. <a href=\"https://doi.org/10.1002/cplu.202000416\">https://doi.org/10.1002/cplu.202000416</a>.","mla":"Hu, Xiaobo, et al. “Hybrid Sequences That Express Both Aromatic Amide and Α‐peptidic Folding Features.” <i>ChemPlusChem</i>, vol. 85, no. 7, Wiley, 2020, pp. 1580–86, doi:<a href=\"https://doi.org/10.1002/cplu.202000416\">10.1002/cplu.202000416</a>.","ista":"Hu X, Mandal PK, Kauffmann B, Huc I. 2020. Hybrid sequences that express both aromatic amide and α‐peptidic folding features. ChemPlusChem. 85(7), 1580–1586."},"publication_status":"published","month":"07","scopus_import":"1","pmid":1,"_id":"21085","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)"},"page":"1580-1586","external_id":{"pmid":["32729681"]},"year":"2020","quality_controlled":"1","issue":"7","doi":"10.1002/cplu.202000416","language":[{"iso":"eng"}],"publisher":"Wiley","date_published":"2020-07-06T00:00:00Z","oa":1,"extern":"1","article_type":"original","author":[{"first_name":"Xiaobo","last_name":"Hu","full_name":"Hu, Xiaobo"},{"full_name":"Mandal, Pradeep K","last_name":"Mandal","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","first_name":"Pradeep K"},{"full_name":"Kauffmann, Brice","last_name":"Kauffmann","first_name":"Brice"},{"full_name":"Huc, Ivan","last_name":"Huc","first_name":"Ivan"}],"abstract":[{"text":"Foldamers combining aliphatic and aromatic main-chain units often produce atypical structures that cannot easily be accessed from purely aromatic or aliphatic sequences. We report solid-state evidence that sequences comprising α-amino acids and quinoline-based monomers adopt conformations that combine the folding propensities of both components. Foldamers 2 and 3 having an XQQ repeat motif (X=α-amino acid, Q=quinoline) were synthesized. Crystals of 2 (X=Phe, Q with an anionic side chain) obtained from water revealed an aromatic helix where amide groups belonging to the α-amino acids created a hydrogen-bond array typical of peptidic helices. Crystals of 3 (X=Ser, Q with a lipophilic side chain) obtained from organic solvents revealed a helix-turn-helix structure in which α-amino acid side chains interfere with main-chain hydrogen bonding. High sequence-dependency of the conformation is typical of peptides but is shown here to include aromatic folding features.","lang":"eng"}],"date_updated":"2026-02-20T06:51:31Z","intvolume":"        85","oa_version":"Published Version","day":"06","title":"Hybrid sequences that express both aromatic amide and α‐peptidic folding features","has_accepted_license":"1","OA_type":"hybrid","publication_identifier":{"eissn":["2192-6506"]},"publication":"ChemPlusChem","status":"public","main_file_link":[{"url":"https://doi.org/10.1002/cplu.202000416","open_access":"1"}],"date_created":"2026-01-29T15:34:50Z","article_processing_charge":"No"},{"extern":"1","article_processing_charge":"No","date_created":"2026-03-30T12:22:48Z","status":"public","date_published":"2020-06-01T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1364/cleo_qels.2020.fm2q.3","publisher":"Optica Publishing Group","quality_controlled":"1","year":"2020","publication":"Conference on Lasers and Electro-Optics","conference":{"end_date":"2020-05-15","name":"CLEO: Fundamental Science","start_date":"2020-05-10","location":"Washington, DC, United States"},"publication_identifier":{"issnl":["2162-2701"],"eisbn":["9781943580767"]},"OA_type":"closed access","_id":"21621","title":"Toward nanophotonic free-electron lasers","day":"01","scopus_import":"1","month":"06","article_number":"FM2Q.3","oa_version":"None","publication_status":"published","date_updated":"2026-05-05T06:49:40Z","citation":{"chicago":"Rivera, Nicholas, Charles Roques-Carmes, Ido Kaminer, and Marin Soljačić. “Toward Nanophotonic Free-Electron Lasers.” In <i>Conference on Lasers and Electro-Optics</i>. Optica Publishing Group, 2020. <a href=\"https://doi.org/10.1364/cleo_qels.2020.fm2q.3\">https://doi.org/10.1364/cleo_qels.2020.fm2q.3</a>.","mla":"Rivera, Nicholas, et al. “Toward Nanophotonic Free-Electron Lasers.” <i>Conference on Lasers and Electro-Optics</i>, FM2Q.3, Optica Publishing Group, 2020, doi:<a href=\"https://doi.org/10.1364/cleo_qels.2020.fm2q.3\">10.1364/cleo_qels.2020.fm2q.3</a>.","ista":"Rivera N, Roques-Carmes C, Kaminer I, Soljačić M. 2020. Toward nanophotonic free-electron lasers. Conference on Lasers and Electro-Optics. CLEO: Fundamental Science, FM2Q.3.","short":"N. Rivera, C. Roques-Carmes, I. Kaminer, M. Soljačić, in:, Conference on Lasers and Electro-Optics, Optica Publishing Group, 2020.","ieee":"N. Rivera, C. Roques-Carmes, I. Kaminer, and M. Soljačić, “Toward nanophotonic free-electron lasers,” in <i>Conference on Lasers and Electro-Optics</i>, Washington, DC, United States, 2020.","apa":"Rivera, N., Roques-Carmes, C., Kaminer, I., &#38; Soljačić, M. (2020). Toward nanophotonic free-electron lasers. In <i>Conference on Lasers and Electro-Optics</i>. Washington, DC, United States: Optica Publishing Group. <a href=\"https://doi.org/10.1364/cleo_qels.2020.fm2q.3\">https://doi.org/10.1364/cleo_qels.2020.fm2q.3</a>","ama":"Rivera N, Roques-Carmes C, Kaminer I, Soljačić M. Toward nanophotonic free-electron lasers. In: <i>Conference on Lasers and Electro-Optics</i>. Optica Publishing Group; 2020. doi:<a href=\"https://doi.org/10.1364/cleo_qels.2020.fm2q.3\">10.1364/cleo_qels.2020.fm2q.3</a>"},"type":"conference","abstract":[{"text":"We show that nanophotonic structures enable the possibility of realizing lasers based on stimulated emission by free electrons. The associated threshold beam currents are in the nanoampere range, and could be realized in electron microscopes.","lang":"eng"}],"author":[{"first_name":"Nicholas","full_name":"Rivera, Nicholas","last_name":"Rivera"},{"full_name":"Roques-Carmes, Charles","last_name":"Roques-Carmes","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82"},{"first_name":"Ido","full_name":"Kaminer, Ido","last_name":"Kaminer"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"oa":1,"doi":"10.1051/0004-6361/202037710","date_published":"2020-08-12T00:00:00Z","language":[{"iso":"eng"}],"publisher":"EDP Sciences","extern":"1","article_type":"original","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"external_id":{"arxiv":["2002.05077"]},"year":"2020","quality_controlled":"1","arxiv":1,"scopus_import":"1","month":"08","_id":"13463","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Renzo, M., et al. “Predictions for the Hydrogen-Free Ejecta of Pulsational Pair-Instability Supernovae.” <i>Astronomy &#38; Astrophysics</i>, vol. 640, A56, EDP Sciences, 2020, doi:<a href=\"https://doi.org/10.1051/0004-6361/202037710\">10.1051/0004-6361/202037710</a>.","chicago":"Renzo, M., R. Farmer, S. Justham, Ylva Louise Linsdotter Götberg, S. E. de Mink, E. Zapartas, P. Marchant, and N. Smith. “Predictions for the Hydrogen-Free Ejecta of Pulsational Pair-Instability Supernovae.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2020. <a href=\"https://doi.org/10.1051/0004-6361/202037710\">https://doi.org/10.1051/0004-6361/202037710</a>.","ista":"Renzo M, Farmer R, Justham S, Götberg YLL, de Mink SE, Zapartas E, Marchant P, Smith N. 2020. Predictions for the hydrogen-free ejecta of pulsational pair-instability supernovae. Astronomy &#38; Astrophysics. 640, A56.","short":"M. Renzo, R. Farmer, S. Justham, Y.L.L. Götberg, S.E. de Mink, E. Zapartas, P. Marchant, N. Smith, Astronomy &#38; Astrophysics 640 (2020).","ieee":"M. Renzo <i>et al.</i>, “Predictions for the hydrogen-free ejecta of pulsational pair-instability supernovae,” <i>Astronomy &#38; Astrophysics</i>, vol. 640. EDP Sciences, 2020.","ama":"Renzo M, Farmer R, Justham S, et al. Predictions for the hydrogen-free ejecta of pulsational pair-instability supernovae. <i>Astronomy &#38; Astrophysics</i>. 2020;640. doi:<a href=\"https://doi.org/10.1051/0004-6361/202037710\">10.1051/0004-6361/202037710</a>","apa":"Renzo, M., Farmer, R., Justham, S., Götberg, Y. L. L., de Mink, S. E., Zapartas, E., … Smith, N. (2020). Predictions for the hydrogen-free ejecta of pulsational pair-instability supernovae. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202037710\">https://doi.org/10.1051/0004-6361/202037710</a>"},"publication_status":"published","type":"journal_article","volume":640,"status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1051/0004-6361/202037710"}],"date_created":"2023-08-03T10:12:58Z","article_processing_charge":"No","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"publication":"Astronomy & Astrophysics","title":"Predictions for the hydrogen-free ejecta of pulsational pair-instability supernovae","day":"12","author":[{"first_name":"M.","full_name":"Renzo, M.","last_name":"Renzo"},{"full_name":"Farmer, R.","last_name":"Farmer","first_name":"R."},{"full_name":"Justham, S.","last_name":"Justham","first_name":"S."},{"full_name":"Götberg, Ylva Louise Linsdotter","last_name":"Götberg","orcid":"0000-0002-6960-6911","id":"d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d","first_name":"Ylva Louise Linsdotter"},{"last_name":"de Mink","full_name":"de Mink, S. E.","first_name":"S. E."},{"first_name":"E.","last_name":"Zapartas","full_name":"Zapartas, E."},{"last_name":"Marchant","full_name":"Marchant, P.","first_name":"P."},{"first_name":"N.","last_name":"Smith","full_name":"Smith, N."}],"intvolume":"       640","date_updated":"2023-08-09T12:58:41Z","oa_version":"Published Version","article_number":"A56","abstract":[{"lang":"eng","text":"Present and upcoming time-domain astronomy efforts, in part driven by gravitational-wave follow-up campaigns, will unveil a variety of rare explosive transients in the sky. Here, we focus on pulsational pair-instability evolution, which can result in signatures that are observable with electromagnetic and gravitational waves. We simulated grids of bare helium stars to characterize the resulting black hole (BH) masses together with the ejecta composition, velocity, and thermal state. We find that the stars do not react “elastically” to the thermonuclear ignition in the core: there is not a one-to-one correspondence between pair-instability driven ignition and mass ejections, which causes ambiguity as to what is an observable pulse. In agreement with previous studies, we find that for initial helium core masses of 37.5 M⊙ ≲ MHe, init ≲ 41 M⊙, corresponding to carbon-oxygen core masses 27.5 M⊙ ≲ MCO ≲ 30.1 M⊙, the explosions are not strong enough to affect the surface. With increasing initial helium core mass, they become progressively stronger causing first large radial expansion (41 M⊙ ≲ MHe, init ≲ 42 M⊙, corresponding to 30.1 M⊙ ≲ MCO ≲ 30.8 M⊙) and, finally, also mass ejection episodes (for MHe, init ≳ 42 M⊙, or MCO ≳ 30.8 M⊙). The lowest mass helium core to be fully disrupted in a pair-instability supernova is MHe, init ≃ 80 M⊙, corresponding to MCO ≃ 55 M⊙. Models with MHe, init ≳ 200 M⊙ (MCO ≳ 114 M⊙) reach the photodisintegration regime, resulting in BHs with masses of MBH ≳ 125 M⊙. Although this is currently considered unlikely, if BHs from these models form via (weak) explosions, the previously-ejected material might be hit by the blast wave and convert kinetic energy into observable electromagnetic radiation. We characterize the hydrogen-free circumstellar material from the pulsational pair-instability of helium cores by simply assuming that the ejecta maintain a constant velocity after ejection. We find that our models produce helium-rich ejecta with mass of 10−3 M⊙ ≲ MCSM ≲ 40 M⊙, the larger values corresponding to the more massive progenitor stars. These ejecta are typically launched at a few thousand km s−1 and reach distances of ∼1012 − 1015 cm before the core-collapse of the star. The delays between mass ejection events and the final collapse span a wide and mass-dependent range (from subhour to 104 years), and the shells ejected can also collide with each other, powering supernova impostor events before the final core-collapse. The range of properties we find suggests a possible connection with (some) type Ibn supernovae."}]}]
