---
OA_type: free access
_id: '21108'
abstract:
- lang: eng
  text: We report here the crystal structure of the partially self-complementary decameric
    sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with
    sticky ends. Each junction binds to four others through Watson–Crick base pairing
    at the sticky ends to form a rhombic structure. The rhombuses bind to each other
    and form two dimensional tiles. The tiles stack to form the crystal. The crystal
    diffracted in the space group P1 to a resolution of 2.5 Å. The junction has the
    anti-parallel stacked-X conformation like other junction structures, though the
    formation of the rhombic net noticeably alters the details of the junction geometry.
article_processing_charge: No
article_type: original
author:
- first_name: S.
  full_name: Venkadesh, S.
  last_name: Venkadesh
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: N.
  full_name: Gautham, N.
  last_name: Gautham
citation:
  ama: Venkadesh S, Mandal PK, Gautham N. The sequence d(CGGCGGCCGC) self-assembles
    into a two dimensional rhombic DNA lattice. <i>Biochemical and Biophysical Research
    Communications</i>. 2011;407(3):548-551. doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.056">10.1016/j.bbrc.2011.03.056</a>
  apa: Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The sequence d(CGGCGGCCGC)
    self-assembles into a two dimensional rhombic DNA lattice. <i>Biochemical and
    Biophysical Research Communications</i>. Elsevier. <a href="https://doi.org/10.1016/j.bbrc.2011.03.056">https://doi.org/10.1016/j.bbrc.2011.03.056</a>
  chicago: Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Sequence d(CGGCGGCCGC)
    Self-Assembles into a Two Dimensional Rhombic DNA Lattice.” <i>Biochemical and
    Biophysical Research Communications</i>. Elsevier, 2011. <a href="https://doi.org/10.1016/j.bbrc.2011.03.056">https://doi.org/10.1016/j.bbrc.2011.03.056</a>.
  ieee: S. Venkadesh, P. K. Mandal, and N. Gautham, “The sequence d(CGGCGGCCGC) self-assembles
    into a two dimensional rhombic DNA lattice,” <i>Biochemical and Biophysical Research
    Communications</i>, vol. 407, no. 3. Elsevier, pp. 548–551, 2011.
  ista: Venkadesh S, Mandal PK, Gautham N. 2011. The sequence d(CGGCGGCCGC) self-assembles
    into a two dimensional rhombic DNA lattice. Biochemical and Biophysical Research
    Communications. 407(3), 548–551.
  mla: Venkadesh, S., et al. “The Sequence d(CGGCGGCCGC) Self-Assembles into a Two
    Dimensional Rhombic DNA Lattice.” <i>Biochemical and Biophysical Research Communications</i>,
    vol. 407, no. 3, Elsevier, 2011, pp. 548–51, doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.056">10.1016/j.bbrc.2011.03.056</a>.
  short: S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research
    Communications 407 (2011) 548–551.
date_created: 2026-01-29T22:09:20Z
date_published: 2011-04-15T00:00:00Z
date_updated: 2026-02-20T09:11:23Z
day: '15'
doi: 10.1016/j.bbrc.2011.03.056
extern: '1'
external_id:
  pmid:
  - '21419105'
has_accepted_license: '1'
intvolume: '       407'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.bbrc.2011.03.056
month: '04'
oa: 1
oa_version: Published Version
page: 548-551
pmid: 1
publication: Biochemical and Biophysical Research Communications
publication_identifier:
  issn:
  - 0006-291X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA
  lattice
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 407
year: '2011'
...
---
OA_type: free access
_id: '21109'
abstract:
- lang: eng
  text: We report the 2.6 Å resolution crystal structure of the tetra-decamer d(CGCGGGTACCCGCG)
    in the tetragonal space group P43. This sequence contains the KpnI restriction
    site GGTACC in the centre which is flanked by alternating ‘CG’ sequences, and
    has a ‘TA’ step at the centre. These are features could favour the left-handed
    Z type helix. Despite this, overall the molecule has the A form. This is the first
    tetra-decamer crystallized in the A-DNA conformation, i.e. more than one full
    turn of the A helix. The crystallographic asymmetric unit consists of one tetra-decamer
    duplex. The helical twist and slide, as well as the base pair–base pair stacking
    interactions show alternations at the alternating pyrimidine–purine and purine–pyrimidine
    base steps. This variation is reminiscent of the dinucleotide repeat in left-handed
    Z-DNA helices. The crystal packing is unlike other A-DNA crystal structures, with
    each helix having a large number of contacts of many different types with symmetry-related
    neighbours.
article_processing_charge: No
article_type: original
author:
- first_name: S.
  full_name: Venkadesh, S.
  last_name: Venkadesh
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: N.
  full_name: Gautham, N.
  last_name: Gautham
citation:
  ama: Venkadesh S, Mandal PK, Gautham N. The structure of a full turn of an A-DNA
    duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical Research Communications</i>.
    2011;407(2):307-312. doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.007">10.1016/j.bbrc.2011.03.007</a>
  apa: Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The structure of a
    full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical
    Research Communications</i>. Elsevier. <a href="https://doi.org/10.1016/j.bbrc.2011.03.007">https://doi.org/10.1016/j.bbrc.2011.03.007</a>
  chicago: Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Structure of a Full
    Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.” <i>Biochemical and Biophysical Research
    Communications</i>. Elsevier, 2011. <a href="https://doi.org/10.1016/j.bbrc.2011.03.007">https://doi.org/10.1016/j.bbrc.2011.03.007</a>.
  ieee: S. Venkadesh, P. K. Mandal, and N. Gautham, “The structure of a full turn
    of an A-DNA duplex d(CGCGGGTACCCGCG)2,” <i>Biochemical and Biophysical Research
    Communications</i>, vol. 407, no. 2. Elsevier, pp. 307–312, 2011.
  ista: Venkadesh S, Mandal PK, Gautham N. 2011. The structure of a full turn of an
    A-DNA duplex d(CGCGGGTACCCGCG)2. Biochemical and Biophysical Research Communications.
    407(2), 307–312.
  mla: Venkadesh, S., et al. “The Structure of a Full Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.”
    <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 2, Elsevier,
    2011, pp. 307–12, doi:<a href="https://doi.org/10.1016/j.bbrc.2011.03.007">10.1016/j.bbrc.2011.03.007</a>.
  short: S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research
    Communications 407 (2011) 307–312.
date_created: 2026-01-29T22:10:30Z
date_published: 2011-04-08T00:00:00Z
date_updated: 2026-02-20T09:01:51Z
day: '08'
doi: 10.1016/j.bbrc.2011.03.007
extern: '1'
external_id:
  pmid:
  - '21397589'
has_accepted_license: '1'
intvolume: '       407'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.bbrc.2011.03.007
month: '04'
oa: 1
oa_version: None
page: 307-312
pmid: 1
publication: Biochemical and Biophysical Research Communications
publication_identifier:
  issn:
  - 0006-291X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 407
year: '2011'
...