---
OA_type: closed access
_id: '3908'
abstract:
- lang: eng
  text: 'It is commonly believed that both the average length and the frequency of
    microsatellites correlate with genome size. We have estimated the frequency and
    the average length for 69 perfect dinucleotide microsatellites in an insect with
    an exceptionally large genome: Chorthippus biguttulus (Orthoptera, Acrididae).
    Dinucleotide microsatellites are not more frequent in C. biguttulus, but repeat
    arrays are 1.4 to 2 times longer than in other insect species. The average repeat
    number in C. biguttulus lies in the range of higher vertebrates. Natural populations
    are highly variable. At least 30 alleles per locus were found and the expected
    heterozygosity is above 0.95 at all three loci studied. In contrast, the observed
    heterozygosity is much lower (≤0.51), which could be caused by long null alleles.'
article_processing_charge: No
article_type: original
author:
- first_name: Jana
  full_name: Ustinova, Jana
  last_name: Ustinova
- first_name: Roland
  full_name: Achmann, Roland
  last_name: Achmann
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Frieder
  full_name: Mayer, Frieder
  last_name: Mayer
citation:
  ama: 'Ustinova J, Achmann R, Cremer S, Mayer F. Long repeats in a huge gemome: microsatellite
    loci in the grasshopper Chorthippus biguttulus. <i>Journal of Molecular Evolution</i>.
    2006;62(2):158-167. doi:<a href="https://doi.org/10.1007/s00239-005-0022-6">10.1007/s00239-005-0022-6</a>'
  apa: 'Ustinova, J., Achmann, R., Cremer, S., &#38; Mayer, F. (2006). Long repeats
    in a huge gemome: microsatellite loci in the grasshopper Chorthippus biguttulus.
    <i>Journal of Molecular Evolution</i>. Springer Nature. <a href="https://doi.org/10.1007/s00239-005-0022-6">https://doi.org/10.1007/s00239-005-0022-6</a>'
  chicago: 'Ustinova, Jana, Roland Achmann, Sylvia Cremer, and Frieder Mayer. “Long
    Repeats in a Huge Gemome: Microsatellite Loci in the Grasshopper Chorthippus Biguttulus.”
    <i>Journal of Molecular Evolution</i>. Springer Nature, 2006. <a href="https://doi.org/10.1007/s00239-005-0022-6">https://doi.org/10.1007/s00239-005-0022-6</a>.'
  ieee: 'J. Ustinova, R. Achmann, S. Cremer, and F. Mayer, “Long repeats in a huge
    gemome: microsatellite loci in the grasshopper Chorthippus biguttulus,” <i>Journal
    of Molecular Evolution</i>, vol. 62, no. 2. Springer Nature, pp. 158–167, 2006.'
  ista: 'Ustinova J, Achmann R, Cremer S, Mayer F. 2006. Long repeats in a huge gemome:
    microsatellite loci in the grasshopper Chorthippus biguttulus. Journal of Molecular
    Evolution. 62(2), 158–167.'
  mla: 'Ustinova, Jana, et al. “Long Repeats in a Huge Gemome: Microsatellite Loci
    in the Grasshopper Chorthippus Biguttulus.” <i>Journal of Molecular Evolution</i>,
    vol. 62, no. 2, Springer Nature, 2006, pp. 158–67, doi:<a href="https://doi.org/10.1007/s00239-005-0022-6">10.1007/s00239-005-0022-6</a>.'
  short: J. Ustinova, R. Achmann, S. Cremer, F. Mayer, Journal of Molecular Evolution
    62 (2006) 158–167.
date_created: 2018-12-11T12:05:49Z
date_published: 2006-02-01T00:00:00Z
date_updated: 2026-08-27T07:31:36Z
day: '01'
doi: 10.1007/s00239-005-0022-6
extern: '1'
external_id:
  pmid:
  - '16474983 '
intvolume: '        62'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 158 - 167
pmid: 1
publication: Journal of Molecular Evolution
publication_identifier:
  eissn:
  - 1432-1432
  issn:
  - 0022-2844
publication_status: published
publisher: Springer Nature
publist_id: '2242'
status: public
title: 'Long repeats in a huge gemome: microsatellite loci in the grasshopper Chorthippus
  biguttulus'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 62
year: '2006'
...
---
_id: '859'
abstract:
- lang: eng
  text: The polymeric ubiquitin (poly-u) genes are composed of tandem 228-bp repeats
    with no spacer sequences between individual monomer units. Ubiquitin is one of
    the most conserved proteins known to date, and the individual units within a number
    of poly-u genes are significantly more similar to each other than would be expected
    if each unit evolved independently. It has been proposed that the rather striking
    similarity among poly-u monomers in some lineages is caused by a series of homogenization
    events. Here we report the sequences of the polyubiquitin-C (Ubc) genes in two
    mouse strains. Analysis of these sequences, as well as those of the previously
    reported Chinese hamster and rat poly-u genes, supports the assertion that the
    homogenization of the ubiquitin-C gene in rodents is due to unequal crossing-over
    events. The sequence divergence of noncoding DNA was used to estimate the frequency
    of unequal crossing-over events (6.3 x 10-5 events per generation) in the Ubc
    gene, as well as to provide evidence of apparent selection in the poly-u gene.
acknowledgement: We are thankful to J.A. Southerland and P.L. Jiang for technical
  assistance in DNA sequencing, as well as to Y.I. Pavlov for helpful discussions.
  This work was supported by public Health Service Research Grant AI45135 from the
  Institute of Allergy and Infectious Diseases, National Institutes of Health.
article_processing_charge: No
article_type: original
author:
- first_name: Andrey
  full_name: Perelygin, Andrey
  last_name: Perelygin
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Igor
  full_name: Rogozin, Igor
  last_name: Rogozin
- first_name: Margo
  full_name: Brinton, Margo
  last_name: Brinton
citation:
  ama: Perelygin A, Kondrashov F, Rogozin I, Brinton M. Evolution of the mouse polyubiquitin
    C gene. <i>Journal of Molecular Evolution</i>. 2002;55(2):202-210. doi:<a href="https://doi.org/10.1007/s00239-002-2318-0">10.1007/s00239-002-2318-0</a>
  apa: Perelygin, A., Kondrashov, F., Rogozin, I., &#38; Brinton, M. (2002). Evolution
    of the mouse polyubiquitin C gene. <i>Journal of Molecular Evolution</i>. Springer.
    <a href="https://doi.org/10.1007/s00239-002-2318-0">https://doi.org/10.1007/s00239-002-2318-0</a>
  chicago: Perelygin, Andrey, Fyodor Kondrashov, Igor Rogozin, and Margo Brinton.
    “Evolution of the Mouse Polyubiquitin C Gene.” <i>Journal of Molecular Evolution</i>.
    Springer, 2002. <a href="https://doi.org/10.1007/s00239-002-2318-0">https://doi.org/10.1007/s00239-002-2318-0</a>.
  ieee: A. Perelygin, F. Kondrashov, I. Rogozin, and M. Brinton, “Evolution of the
    mouse polyubiquitin C gene,” <i>Journal of Molecular Evolution</i>, vol. 55, no.
    2. Springer, pp. 202–210, 2002.
  ista: Perelygin A, Kondrashov F, Rogozin I, Brinton M. 2002. Evolution of the mouse
    polyubiquitin C gene. Journal of Molecular Evolution. 55(2), 202–210.
  mla: Perelygin, Andrey, et al. “Evolution of the Mouse Polyubiquitin C Gene.” <i>Journal
    of Molecular Evolution</i>, vol. 55, no. 2, Springer, 2002, pp. 202–10, doi:<a
    href="https://doi.org/10.1007/s00239-002-2318-0">10.1007/s00239-002-2318-0</a>.
  short: A. Perelygin, F. Kondrashov, I. Rogozin, M. Brinton, Journal of Molecular
    Evolution 55 (2002) 202–210.
date_created: 2018-12-11T11:48:53Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-26T12:01:34Z
day: '01'
doi: 10.1007/s00239-002-2318-0
extern: '1'
external_id:
  pmid:
  - '12107596'
intvolume: '        55'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 202 - 210
pmid: 1
publication: Journal of Molecular Evolution
publication_identifier:
  issn:
  - 0022-2844
publication_status: published
publisher: Springer
publist_id: '6787'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolution of the mouse polyubiquitin C gene
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 55
year: '2002'
...
---
_id: '4229'
abstract:
- lang: eng
  text: Bacteriophage of the family Leviviridae have played an important role in molecular
    biology where representative species, such as Qβ and MS2, have been studied as
    model systems for replication, translation, and the role of secondary structure
    in gene regulation. Using nucleotide sequences from the coat and replicase genes
    we present the first statistical estimate of phylogeny for the family Leviviridae
    using maximum-likelihood and Bayesian estimation. Our analyses reveal that the
    coliphage species are a monophyletic group consisting of two clades representing
    the genera Levivirus and Allolevivirus. The Pseudomonas species PP7 diverged from
    its common ancestor with the coliphage prior to the ancient split between these
    genera and their subsequent diversification. Differences in genome size, gene
    composition, and gene expression are shown with a high probability to have changed
    along the lineage leading to the Allolevivirus through gene expansion. The change
    in genome size of the Allolevivirus ancestor may have catalyzed subsequent changes
    that led to their current genome organization and gene expression.
acknowledgement: "We thank Kenneth G. Karol, Andrea J. Betancourt, Daven C. Presgraves,
  and Bret Larget for helpful comments and\r\nsuggestions. This work was supported
  by funding from the National Science Foundation (MCB-0075404 and DEB-0075406) to
  J.P.H."
article_processing_charge: No
article_type: original
author:
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
- first_name: John
  full_name: Huelsenbeck, John
  last_name: Huelsenbeck
citation:
  ama: Bollback JP, Huelsenbeck J. Phylogeny, genome evolution, and host specificity
    of single-stranded RNA bacteriophage (Family Leviviridae). <i>Journal of Molecular
    Evolution</i>. 2001;52(2):117-128. doi:<a href="https://doi.org/10.1007/s002390010140">10.1007/s002390010140</a>
  apa: Bollback, J. P., &#38; Huelsenbeck, J. (2001). Phylogeny, genome evolution,
    and host specificity of single-stranded RNA bacteriophage (Family Leviviridae).
    <i>Journal of Molecular Evolution</i>. Springer. <a href="https://doi.org/10.1007/s002390010140">https://doi.org/10.1007/s002390010140</a>
  chicago: Bollback, Jonathan P, and John Huelsenbeck. “Phylogeny, Genome Evolution,
    and Host Specificity of Single-Stranded RNA Bacteriophage (Family Leviviridae).”
    <i>Journal of Molecular Evolution</i>. Springer, 2001. <a href="https://doi.org/10.1007/s002390010140">https://doi.org/10.1007/s002390010140</a>.
  ieee: J. P. Bollback and J. Huelsenbeck, “Phylogeny, genome evolution, and host
    specificity of single-stranded RNA bacteriophage (Family Leviviridae),” <i>Journal
    of Molecular Evolution</i>, vol. 52, no. 2. Springer, pp. 117–128, 2001.
  ista: Bollback JP, Huelsenbeck J. 2001. Phylogeny, genome evolution, and host specificity
    of single-stranded RNA bacteriophage (Family Leviviridae). Journal of Molecular
    Evolution. 52(2), 117–128.
  mla: Bollback, Jonathan P., and John Huelsenbeck. “Phylogeny, Genome Evolution,
    and Host Specificity of Single-Stranded RNA Bacteriophage (Family Leviviridae).”
    <i>Journal of Molecular Evolution</i>, vol. 52, no. 2, Springer, 2001, pp. 117–28,
    doi:<a href="https://doi.org/10.1007/s002390010140">10.1007/s002390010140</a>.
  short: J.P. Bollback, J. Huelsenbeck, Journal of Molecular Evolution 52 (2001) 117–128.
date_created: 2018-12-11T12:07:43Z
date_published: 2001-02-01T00:00:00Z
date_updated: 2023-05-10T12:23:49Z
day: '01'
doi: 10.1007/s002390010140
extern: '1'
external_id:
  pmid:
  - '11231891'
intvolume: '        52'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 117 - 128
pmid: 1
publication: Journal of Molecular Evolution
publication_identifier:
  issn:
  - 0022-2844
publication_status: published
publisher: Springer
publist_id: '1886'
quality_controlled: '1'
status: public
title: Phylogeny, genome evolution, and host specificity of single-stranded RNA bacteriophage
  (Family Leviviridae)
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 52
year: '2001'
...
