---
_id: '5767'
abstract:
- lang: eng
text: 'Cuprate superconductors have long been thought of as having strong electronic
correlations but negligible spin-orbit coupling. Using spin- and angle-resolved
photoemission spectroscopy, we discovered that one of the most studied cuprate
superconductors, Bi2212, has a nontrivial spin texture with a spin-momentum locking
that circles the Brillouin zone center and a spin-layer locking that allows states
of opposite spin to be localized in different parts of the unit cell. Our findings
pose challenges for the vast majority of models of cuprates, such as the Hubbard
model and its variants, where spin-orbit interaction has been mostly neglected,
and open the intriguing question of how the high-temperature superconducting state
emerges in the presence of this nontrivial spin texture. '
acknowledgement: ' M.S. was supported by the Gordon and Betty Moore Foundation s EPiQS
Initiative through grant GBMF4307'
article_processing_charge: No
article_type: original
author:
- first_name: Kenneth
full_name: Gotlieb, Kenneth
last_name: Gotlieb
- first_name: Chiu-Yun
full_name: Lin, Chiu-Yun
last_name: Lin
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Wentao
full_name: Zhang, Wentao
last_name: Zhang
- first_name: Christopher L.
full_name: Smallwood, Christopher L.
last_name: Smallwood
- first_name: Christopher
full_name: Jozwiak, Christopher
last_name: Jozwiak
- first_name: Hiroshi
full_name: Eisaki, Hiroshi
last_name: Eisaki
- first_name: Zahid
full_name: Hussain, Zahid
last_name: Hussain
- first_name: Ashvin
full_name: Vishwanath, Ashvin
last_name: Vishwanath
- first_name: Alessandra
full_name: Lanzara, Alessandra
last_name: Lanzara
citation:
ama: Gotlieb K, Lin C-Y, Serbyn M, et al. Revealing hidden spin-momentum locking
in a high-temperature cuprate superconductor. Science. 2018;362(6420):1271-1275.
doi:10.1126/science.aao0980
apa: Gotlieb, K., Lin, C.-Y., Serbyn, M., Zhang, W., Smallwood, C. L., Jozwiak,
C., … Lanzara, A. (2018). Revealing hidden spin-momentum locking in a high-temperature
cuprate superconductor. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.aao0980
chicago: Gotlieb, Kenneth, Chiu-Yun Lin, Maksym Serbyn, Wentao Zhang, Christopher
L. Smallwood, Christopher Jozwiak, Hiroshi Eisaki, Zahid Hussain, Ashvin Vishwanath,
and Alessandra Lanzara. “Revealing Hidden Spin-Momentum Locking in a High-Temperature
Cuprate Superconductor.” Science. American Association for the Advancement
of Science, 2018. https://doi.org/10.1126/science.aao0980.
ieee: K. Gotlieb et al., “Revealing hidden spin-momentum locking in a high-temperature
cuprate superconductor,” Science, vol. 362, no. 6420. American Association
for the Advancement of Science, pp. 1271–1275, 2018.
ista: Gotlieb K, Lin C-Y, Serbyn M, Zhang W, Smallwood CL, Jozwiak C, Eisaki H,
Hussain Z, Vishwanath A, Lanzara A. 2018. Revealing hidden spin-momentum locking
in a high-temperature cuprate superconductor. Science. 362(6420), 1271–1275.
mla: Gotlieb, Kenneth, et al. “Revealing Hidden Spin-Momentum Locking in a High-Temperature
Cuprate Superconductor.” Science, vol. 362, no. 6420, American Association
for the Advancement of Science, 2018, pp. 1271–75, doi:10.1126/science.aao0980.
short: K. Gotlieb, C.-Y. Lin, M. Serbyn, W. Zhang, C.L. Smallwood, C. Jozwiak, H.
Eisaki, Z. Hussain, A. Vishwanath, A. Lanzara, Science 362 (2018) 1271–1275.
date_created: 2018-12-19T14:53:50Z
date_published: 2018-12-14T00:00:00Z
date_updated: 2026-06-18T18:55:21Z
day: '14'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1126/science.aao0980
external_id:
isi:
- '000452994400048'
intvolume: ' 362'
isi: 1
issue: '6420'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1126/science.aao0980
month: '12'
oa: 1
oa_version: Published Version
page: 1271-1275
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 362
year: '2018'
...
---
_id: '7718'
abstract:
- lang: eng
text: Flores Island, Indonesia, was inhabited by the small-bodied hominin species
Homo floresiensis, which has an unknown evolutionary relationship to modern humans.
This island is also home to an extant human pygmy population. Here we describe
genome-scale single-nucleotide polymorphism data and whole-genome sequences from
a contemporary human pygmy population living on Flores near the cave where H.
floresiensis was found. The genomes of Flores pygmies reveal a complex history
of admixture with Denisovans and Neanderthals but no evidence for gene flow with
other archaic hominins. Modern individuals bear the signatures of recent positive
selection encompassing the FADS (fatty acid desaturase) gene cluster, likely related
to diet, and polygenic selection acting on standing variation that contributed
to their short-stature phenotype. Thus, multiple independent instances of hominin
insular dwarfism occurred on Flores.
article_processing_charge: No
article_type: original
author:
- first_name: Serena
full_name: Tucci, Serena
last_name: Tucci
- first_name: Samuel H.
full_name: Vohr, Samuel H.
last_name: Vohr
- first_name: Rajiv C.
full_name: McCoy, Rajiv C.
last_name: McCoy
- first_name: Benjamin
full_name: Vernot, Benjamin
last_name: Vernot
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
- first_name: Chiara
full_name: Barbieri, Chiara
last_name: Barbieri
- first_name: Brad J.
full_name: Nelson, Brad J.
last_name: Nelson
- first_name: Wenqing
full_name: Fu, Wenqing
last_name: Fu
- first_name: Gludhug A.
full_name: Purnomo, Gludhug A.
last_name: Purnomo
- first_name: Herawati
full_name: Sudoyo, Herawati
last_name: Sudoyo
- first_name: Evan E.
full_name: Eichler, Evan E.
last_name: Eichler
- first_name: Guido
full_name: Barbujani, Guido
last_name: Barbujani
- first_name: Peter M.
full_name: Visscher, Peter M.
last_name: Visscher
- first_name: Joshua M.
full_name: Akey, Joshua M.
last_name: Akey
- first_name: Richard E.
full_name: Green, Richard E.
last_name: Green
citation:
ama: Tucci S, Vohr SH, McCoy RC, et al. Evolutionary history and adaptation of a
human pygmy population of Flores Island, Indonesia. Science. 2018;361(6401):511-516.
doi:10.1126/science.aar8486
apa: Tucci, S., Vohr, S. H., McCoy, R. C., Vernot, B., Robinson, M. R., Barbieri,
C., … Green, R. E. (2018). Evolutionary history and adaptation of a human pygmy
population of Flores Island, Indonesia. Science. American Association for
the Advancement of Science. https://doi.org/10.1126/science.aar8486
chicago: Tucci, Serena, Samuel H. Vohr, Rajiv C. McCoy, Benjamin Vernot, Matthew
Richard Robinson, Chiara Barbieri, Brad J. Nelson, et al. “Evolutionary History
and Adaptation of a Human Pygmy Population of Flores Island, Indonesia.” Science.
American Association for the Advancement of Science, 2018. https://doi.org/10.1126/science.aar8486.
ieee: S. Tucci et al., “Evolutionary history and adaptation of a human pygmy
population of Flores Island, Indonesia,” Science, vol. 361, no. 6401. American
Association for the Advancement of Science, pp. 511–516, 2018.
ista: Tucci S, Vohr SH, McCoy RC, Vernot B, Robinson MR, Barbieri C, Nelson BJ,
Fu W, Purnomo GA, Sudoyo H, Eichler EE, Barbujani G, Visscher PM, Akey JM, Green
RE. 2018. Evolutionary history and adaptation of a human pygmy population of Flores
Island, Indonesia. Science. 361(6401), 511–516.
mla: Tucci, Serena, et al. “Evolutionary History and Adaptation of a Human Pygmy
Population of Flores Island, Indonesia.” Science, vol. 361, no. 6401, American
Association for the Advancement of Science, 2018, pp. 511–16, doi:10.1126/science.aar8486.
short: S. Tucci, S.H. Vohr, R.C. McCoy, B. Vernot, M.R. Robinson, C. Barbieri, B.J.
Nelson, W. Fu, G.A. Purnomo, H. Sudoyo, E.E. Eichler, G. Barbujani, P.M. Visscher,
J.M. Akey, R.E. Green, Science 361 (2018) 511–516.
date_created: 2020-04-30T10:43:24Z
date_published: 2018-08-03T00:00:00Z
date_updated: 2021-01-12T08:15:04Z
day: '03'
doi: 10.1126/science.aar8486
extern: '1'
external_id:
pmid:
- '30072539'
intvolume: ' 361'
issue: '6401'
language:
- iso: eng
month: '08'
oa_version: None
page: 511-516
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
- 1095-9203
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
status: public
title: Evolutionary history and adaptation of a human pygmy population of Flores Island,
Indonesia
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 361
year: '2018'
...
---
_id: '7060'
abstract:
- lang: eng
text: The anomalous metallic state in the high-temperature superconducting cuprates
is masked by superconductivity near a quantum critical point. Applying high magnetic
fields to suppress superconductivity has enabled detailed studies of the normal
state, yet the direct effect of strong magnetic fields on the metallic state is
poorly understood. We report the high-field magnetoresistance of thin-film La2–xSrxCuO4
cuprate in the vicinity of the critical doping, 0.161 ≤ p ≤ 0.190. We find that
the metallic state exposed by suppressing superconductivity is characterized by
magnetoresistance that is linear in magnetic fields up to 80 tesla. The magnitude
of the linear-in-field resistivity mirrors the magnitude and doping evolution
of the well-known linear-in-temperature resistivity that has been associated with
quantum criticality in high-temperature superconductors.
article_processing_charge: No
article_type: original
author:
- first_name: P.
full_name: Giraldo-Gallo, P.
last_name: Giraldo-Gallo
- first_name: J. A.
full_name: Galvis, J. A.
last_name: Galvis
- first_name: Z.
full_name: Stegen, Z.
last_name: Stegen
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
- first_name: F. F.
full_name: Balakirev, F. F.
last_name: Balakirev
- first_name: J. B.
full_name: Betts, J. B.
last_name: Betts
- first_name: X.
full_name: Lian, X.
last_name: Lian
- first_name: C.
full_name: Moir, C.
last_name: Moir
- first_name: S. C.
full_name: Riggs, S. C.
last_name: Riggs
- first_name: J.
full_name: Wu, J.
last_name: Wu
- first_name: A. T.
full_name: Bollinger, A. T.
last_name: Bollinger
- first_name: X.
full_name: He, X.
last_name: He
- first_name: I.
full_name: Božović, I.
last_name: Božović
- first_name: B. J.
full_name: Ramshaw, B. J.
last_name: Ramshaw
- first_name: R. D.
full_name: McDonald, R. D.
last_name: McDonald
- first_name: G. S.
full_name: Boebinger, G. S.
last_name: Boebinger
- first_name: A.
full_name: Shekhter, A.
last_name: Shekhter
citation:
ama: Giraldo-Gallo P, Galvis JA, Stegen Z, et al. Scale-invariant magnetoresistance
in a cuprate superconductor. Science. 2018;361(6401):479-481. doi:10.1126/science.aan3178
apa: Giraldo-Gallo, P., Galvis, J. A., Stegen, Z., Modic, K. A., Balakirev, F. F.,
Betts, J. B., … Shekhter, A. (2018). Scale-invariant magnetoresistance in a cuprate
superconductor. Science. AAAS. https://doi.org/10.1126/science.aan3178
chicago: Giraldo-Gallo, P., J. A. Galvis, Z. Stegen, Kimberly A Modic, F. F. Balakirev,
J. B. Betts, X. Lian, et al. “Scale-Invariant Magnetoresistance in a Cuprate Superconductor.”
Science. AAAS, 2018. https://doi.org/10.1126/science.aan3178.
ieee: P. Giraldo-Gallo et al., “Scale-invariant magnetoresistance in a cuprate
superconductor,” Science, vol. 361, no. 6401. AAAS, pp. 479–481, 2018.
ista: Giraldo-Gallo P, Galvis JA, Stegen Z, Modic KA, Balakirev FF, Betts JB, Lian
X, Moir C, Riggs SC, Wu J, Bollinger AT, He X, Božović I, Ramshaw BJ, McDonald
RD, Boebinger GS, Shekhter A. 2018. Scale-invariant magnetoresistance in a cuprate
superconductor. Science. 361(6401), 479–481.
mla: Giraldo-Gallo, P., et al. “Scale-Invariant Magnetoresistance in a Cuprate Superconductor.”
Science, vol. 361, no. 6401, AAAS, 2018, pp. 479–81, doi:10.1126/science.aan3178.
short: P. Giraldo-Gallo, J.A. Galvis, Z. Stegen, K.A. Modic, F.F. Balakirev, J.B.
Betts, X. Lian, C. Moir, S.C. Riggs, J. Wu, A.T. Bollinger, X. He, I. Božović,
B.J. Ramshaw, R.D. McDonald, G.S. Boebinger, A. Shekhter, Science 361 (2018) 479–481.
date_created: 2019-11-19T13:03:16Z
date_published: 2018-08-03T00:00:00Z
date_updated: 2021-01-12T08:11:37Z
day: '03'
doi: 10.1126/science.aan3178
extern: '1'
intvolume: ' 361'
issue: '6401'
language:
- iso: eng
month: '08'
oa_version: None
page: 479-481
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
status: public
title: Scale-invariant magnetoresistance in a cuprate superconductor
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 361
year: '2018'
...
---
_id: '1132'
abstract:
- lang: eng
text: The hippocampus is thought to initiate systems-wide mnemonic processes through
the reactivation of previously acquired spatial and episodic memory traces, which
can recruit the entorhinal cortex as a first stage of memory redistribution to
other brain areas. Hippocampal reactivation occurs during sharp wave-ripples,
in which synchronous network firing encodes sequences of places.We investigated
the coordination of this replay by recording assembly activity simultaneously
in the CA1 region of the hippocampus and superficial layers of the medial entorhinal
cortex. We found that entorhinal cell assemblies can replay trajectories independently
of the hippocampus and sharp wave-ripples. This suggests that the hippocampus
is not the sole initiator of spatial and episodic memory trace reactivation. Memory
systems involved in these processes may include nonhierarchical, parallel components.
article_processing_charge: No
author:
- first_name: Joseph
full_name: O'Neill, Joseph
id: 426376DC-F248-11E8-B48F-1D18A9856A87
last_name: O'Neill
- first_name: Charlotte
full_name: Boccara, Charlotte
id: 3FC06552-F248-11E8-B48F-1D18A9856A87
last_name: Boccara
orcid: 0000-0001-7237-5109
- first_name: Federico
full_name: Stella, Federico
id: 39AF1E74-F248-11E8-B48F-1D18A9856A87
last_name: Stella
orcid: 0000-0001-9439-3148
- first_name: Philipp
full_name: Schönenberger, Philipp
id: 3B9D816C-F248-11E8-B48F-1D18A9856A87
last_name: Schönenberger
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
citation:
ama: O’Neill J, Boccara CN, Stella F, Schönenberger P, Csicsvari JL. Superficial
layers of the medial entorhinal cortex replay independently of the hippocampus.
Science. 2017;355(6321):184-188. doi:10.1126/science.aag2787
apa: O’Neill, J., Boccara, C. N., Stella, F., Schönenberger, P., & Csicsvari,
J. L. (2017). Superficial layers of the medial entorhinal cortex replay independently
of the hippocampus. Science. American Association for the Advancement of
Science. https://doi.org/10.1126/science.aag2787
chicago: O’Neill, Joseph, Charlotte N. Boccara, Federico Stella, Philipp Schönenberger,
and Jozsef L Csicsvari. “Superficial Layers of the Medial Entorhinal Cortex Replay
Independently of the Hippocampus.” Science. American Association for the
Advancement of Science, 2017. https://doi.org/10.1126/science.aag2787.
ieee: J. O’Neill, C. N. Boccara, F. Stella, P. Schönenberger, and J. L. Csicsvari,
“Superficial layers of the medial entorhinal cortex replay independently of the
hippocampus,” Science, vol. 355, no. 6321. American Association for the
Advancement of Science, pp. 184–188, 2017.
ista: O’Neill J, Boccara CN, Stella F, Schönenberger P, Csicsvari JL. 2017. Superficial
layers of the medial entorhinal cortex replay independently of the hippocampus.
Science. 355(6321), 184–188.
mla: O’Neill, Joseph, et al. “Superficial Layers of the Medial Entorhinal Cortex
Replay Independently of the Hippocampus.” Science, vol. 355, no. 6321,
American Association for the Advancement of Science, 2017, pp. 184–88, doi:10.1126/science.aag2787.
short: J. O’Neill, C.N. Boccara, F. Stella, P. Schönenberger, J.L. Csicsvari, Science
355 (2017) 184–188.
date_created: 2018-12-11T11:50:19Z
date_published: 2017-01-13T00:00:00Z
date_updated: 2025-07-10T11:50:09Z
day: '13'
ddc:
- '571'
department:
- _id: JoCs
doi: 10.1126/science.aag2787
ec_funded: 1
external_id:
isi:
- '000391743700044'
file:
- access_level: open_access
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:22Z
date_updated: 2018-12-12T10:10:22Z
file_id: '4809'
file_name: IST-2018-976-v1+1_2017Preprint_ONeill_Superficial_layers.pdf
file_size: 3761201
relation: main_file
file_date_updated: 2018-12-12T10:10:22Z
has_accepted_license: '1'
intvolume: ' 355'
isi: 1
issue: '6321'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 184 - 188
project:
- _id: 257A4776-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '281511'
name: Memory-related information processing in neuronal circuits of the hippocampus
and entorhinal cortex
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '6226'
pubrep_id: '976'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Superficial layers of the medial entorhinal cortex replay independently of
the hippocampus
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 355
year: '2017'
...
---
_id: '13381'
abstract:
- lang: eng
text: Self-assembly of inorganic nanoparticles has been used to prepare hundreds
of different colloidal crystals, but almost invariably with the restriction that
the particles must be densely packed. Here, we show that non–close-packed nanoparticle
arrays can be fabricated through the selective removal of one of two components
comprising binary nanoparticle superlattices. First, a variety of binary nanoparticle
superlattices were prepared at the liquid-air interface, including several arrangements
that were previously unknown. Molecular dynamics simulations revealed the particular
role of the liquid in templating the formation of superlattices not achievable
through self-assembly in bulk solution. Second, upon stabilization, all of these
binary superlattices could be transformed into distinct “nanoallotropes”—nanoporous
materials having the same chemical composition but differing in their nanoscale
architectures.
article_processing_charge: No
article_type: original
author:
- first_name: Thumu
full_name: Udayabhaskararao, Thumu
last_name: Udayabhaskararao
- first_name: Thomas
full_name: Altantzis, Thomas
last_name: Altantzis
- first_name: Lothar
full_name: Houben, Lothar
last_name: Houben
- first_name: Marc
full_name: Coronado-Puchau, Marc
last_name: Coronado-Puchau
- first_name: Judith
full_name: Langer, Judith
last_name: Langer
- first_name: Ronit
full_name: Popovitz-Biro, Ronit
last_name: Popovitz-Biro
- first_name: Luis M.
full_name: Liz-Marzán, Luis M.
last_name: Liz-Marzán
- first_name: Lela
full_name: Vuković, Lela
last_name: Vuković
- first_name: Petr
full_name: Král, Petr
last_name: Král
- first_name: Sara
full_name: Bals, Sara
last_name: Bals
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Udayabhaskararao T, Altantzis T, Houben L, et al. Tunable porous nanoallotropes
prepared by post-assembly etching of binary nanoparticle superlattices. Science.
2017;358(6362):514-518. doi:10.1126/science.aan6046
apa: Udayabhaskararao, T., Altantzis, T., Houben, L., Coronado-Puchau, M., Langer,
J., Popovitz-Biro, R., … Klajn, R. (2017). Tunable porous nanoallotropes prepared
by post-assembly etching of binary nanoparticle superlattices. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.aan6046
chicago: Udayabhaskararao, Thumu, Thomas Altantzis, Lothar Houben, Marc Coronado-Puchau,
Judith Langer, Ronit Popovitz-Biro, Luis M. Liz-Marzán, et al. “Tunable Porous
Nanoallotropes Prepared by Post-Assembly Etching of Binary Nanoparticle Superlattices.”
Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aan6046.
ieee: T. Udayabhaskararao et al., “Tunable porous nanoallotropes prepared
by post-assembly etching of binary nanoparticle superlattices,” Science,
vol. 358, no. 6362. American Association for the Advancement of Science, pp. 514–518,
2017.
ista: Udayabhaskararao T, Altantzis T, Houben L, Coronado-Puchau M, Langer J, Popovitz-Biro
R, Liz-Marzán LM, Vuković L, Král P, Bals S, Klajn R. 2017. Tunable porous nanoallotropes
prepared by post-assembly etching of binary nanoparticle superlattices. Science.
358(6362), 514–518.
mla: Udayabhaskararao, Thumu, et al. “Tunable Porous Nanoallotropes Prepared by
Post-Assembly Etching of Binary Nanoparticle Superlattices.” Science, vol.
358, no. 6362, American Association for the Advancement of Science, 2017, pp.
514–18, doi:10.1126/science.aan6046.
short: T. Udayabhaskararao, T. Altantzis, L. Houben, M. Coronado-Puchau, J. Langer,
R. Popovitz-Biro, L.M. Liz-Marzán, L. Vuković, P. Král, S. Bals, R. Klajn, Science
358 (2017) 514–518.
date_created: 2023-08-01T09:41:16Z
date_published: 2017-10-27T00:00:00Z
date_updated: 2024-10-14T12:15:38Z
day: '27'
doi: 10.1126/science.aan6046
extern: '1'
external_id:
pmid:
- '29074773'
intvolume: ' 358'
issue: '6362'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://repository.uantwerpen.be/docman/irua/8d722e/147242_2018_06_07.pdf
month: '10'
oa: 1
oa_version: Submitted Version
page: 514-518
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tunable porous nanoallotropes prepared by post-assembly etching of binary nanoparticle
superlattices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 358
year: '2017'
...
---
_id: '13384'
abstract:
- lang: eng
text: Although methane is a volatile gas, it can be efficiently trapped in ice,
which can then be readily set on fire. Beyond the curiosity of this “burning ice,”
caged methane is of great importance as one of the world's largest natural gas
resources. In these materials, known as clathrates, methane molecules are tightly
bound in nanometer-sized, regularly interspaced cages. Other inorganic materials,
such as the silica mineral chibaite, can similarly encapsulate methane and higher
hydrocarbons. Simple organic compounds have also been found to trap various organic
molecules upon crystallization.
article_processing_charge: No
article_type: original
author:
- first_name: Dipak
full_name: Samanta, Dipak
last_name: Samanta
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Samanta D, Klajn R. Clathrates grow up. Science. 2017;355(6328):912-912.
doi:10.1126/science.aam7927
apa: Samanta, D., & Klajn, R. (2017). Clathrates grow up. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.aam7927
chicago: Samanta, Dipak, and Rafal Klajn. “Clathrates Grow Up.” Science.
American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aam7927.
ieee: D. Samanta and R. Klajn, “Clathrates grow up,” Science, vol. 355, no.
6328. American Association for the Advancement of Science, pp. 912–912, 2017.
ista: Samanta D, Klajn R. 2017. Clathrates grow up. Science. 355(6328), 912–912.
mla: Samanta, Dipak, and Rafal Klajn. “Clathrates Grow Up.” Science, vol.
355, no. 6328, American Association for the Advancement of Science, 2017, pp.
912–912, doi:10.1126/science.aam7927.
short: D. Samanta, R. Klajn, Science 355 (2017) 912–912.
date_created: 2023-08-01T09:41:55Z
date_published: 2017-03-03T00:00:00Z
date_updated: 2024-10-14T12:16:09Z
day: '03'
doi: 10.1126/science.aam7927
extern: '1'
external_id:
pmid:
- '28254902'
intvolume: ' 355'
issue: '6328'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '03'
oa_version: None
page: 912-912
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Clathrates grow up
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 355
year: '2017'
...
---
_id: '14008'
abstract:
- lang: eng
text: Time-resolved x-ray absorption spectroscopy (TR-XAS) has so far practically
been limited to large-scale facilities, to subpicosecond temporal resolution,
and to the condensed phase. We report the realization of TR-XAS with a temporal
resolution in the low femtosecond range by developing a tabletop high-harmonic
source reaching up to 350 electron volts, thus partially covering the spectral
region of 280 to 530 electron volts, where water is transmissive. We used this
source to follow previously unexamined light-induced chemical reactions in the
lowest electronic states of isolated CF4+ and SF6+ molecules in the gas phase.
By probing element-specific core-to-valence transitions at the carbon K-edge or
the sulfur L-edges, we characterized their reaction paths and observed the effect
of symmetry breaking through the splitting of absorption bands and Rydberg-valence
mixing induced by the geometry changes.
article_processing_charge: No
article_type: original
author:
- first_name: Yoann
full_name: Pertot, Yoann
last_name: Pertot
- first_name: Cédric
full_name: Schmidt, Cédric
last_name: Schmidt
- first_name: Mary
full_name: Matthews, Mary
last_name: Matthews
- first_name: Adrien
full_name: Chauvet, Adrien
last_name: Chauvet
- first_name: Martin
full_name: Huppert, Martin
last_name: Huppert
- first_name: Vit
full_name: Svoboda, Vit
last_name: Svoboda
- first_name: Aaron
full_name: von Conta, Aaron
last_name: von Conta
- first_name: Andres
full_name: Tehlar, Andres
last_name: Tehlar
- first_name: Denitsa Rangelova
full_name: Baykusheva, Denitsa Rangelova
id: 71b4d059-2a03-11ee-914d-dfa3beed6530
last_name: Baykusheva
- first_name: Jean-Pierre
full_name: Wolf, Jean-Pierre
last_name: Wolf
- first_name: Hans Jakob
full_name: Wörner, Hans Jakob
last_name: Wörner
citation:
ama: Pertot Y, Schmidt C, Matthews M, et al. Time-resolved x-ray absorption spectroscopy
with a water window high-harmonic source. Science. 2017;355(6322):264-267.
doi:10.1126/science.aah6114
apa: Pertot, Y., Schmidt, C., Matthews, M., Chauvet, A., Huppert, M., Svoboda, V.,
… Wörner, H. J. (2017). Time-resolved x-ray absorption spectroscopy with a water
window high-harmonic source. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.aah6114
chicago: Pertot, Yoann, Cédric Schmidt, Mary Matthews, Adrien Chauvet, Martin Huppert,
Vit Svoboda, Aaron von Conta, et al. “Time-Resolved x-Ray Absorption Spectroscopy
with a Water Window High-Harmonic Source.” Science. American Association
for the Advancement of Science, 2017. https://doi.org/10.1126/science.aah6114.
ieee: Y. Pertot et al., “Time-resolved x-ray absorption spectroscopy with
a water window high-harmonic source,” Science, vol. 355, no. 6322. American
Association for the Advancement of Science, pp. 264–267, 2017.
ista: Pertot Y, Schmidt C, Matthews M, Chauvet A, Huppert M, Svoboda V, von Conta
A, Tehlar A, Baykusheva DR, Wolf J-P, Wörner HJ. 2017. Time-resolved x-ray absorption
spectroscopy with a water window high-harmonic source. Science. 355(6322), 264–267.
mla: Pertot, Yoann, et al. “Time-Resolved x-Ray Absorption Spectroscopy with a Water
Window High-Harmonic Source.” Science, vol. 355, no. 6322, American Association
for the Advancement of Science, 2017, pp. 264–67, doi:10.1126/science.aah6114.
short: Y. Pertot, C. Schmidt, M. Matthews, A. Chauvet, M. Huppert, V. Svoboda, A.
von Conta, A. Tehlar, D.R. Baykusheva, J.-P. Wolf, H.J. Wörner, Science 355 (2017)
264–267.
date_created: 2023-08-10T06:36:39Z
date_published: 2017-01-05T00:00:00Z
date_updated: 2023-08-22T08:34:38Z
day: '05'
doi: 10.1126/science.aah6114
extern: '1'
external_id:
pmid:
- '28059713'
intvolume: ' 355'
issue: '6322'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '01'
oa_version: None
page: 264-267
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Time-resolved x-ray absorption spectroscopy with a water window high-harmonic
source
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 355
year: '2017'
...
---
_id: '14287'
abstract:
- lang: eng
text: We describe an approach to bottom-up fabrication that allows integration of
the functional diversity of proteins into designed three-dimensional structural
frameworks. A set of custom staple proteins based on transcription activator–like
effector proteins folds a double-stranded DNA template into a user-defined shape.
Each staple protein is designed to recognize and closely link two distinct double-helical
DNA sequences at separate positions on the template. We present design rules for
constructing megadalton-scale DNA-protein hybrid shapes; introduce various structural
motifs, such as custom curvature, corners, and vertices; and describe principles
for creating multilayer DNA-protein objects with enhanced rigidity. We demonstrate
self-assembly of our hybrid nanostructures in one-pot mixtures that include the
genetic information for the designed proteins, the template DNA, RNA polymerase,
ribosomes, and cofactors for transcription and translation.
article_number: eaam5488
article_processing_charge: No
article_type: original
author:
- first_name: Florian M
full_name: Praetorius, Florian M
id: dfec9381-4341-11ee-8fd8-faa02bba7d62
last_name: Praetorius
- first_name: Hendrik
full_name: Dietz, Hendrik
last_name: Dietz
citation:
ama: Praetorius FM, Dietz H. Self-assembly of genetically encoded DNA-protein hybrid
nanoscale shapes. Science. 2017;355(6331). doi:10.1126/science.aam5488
apa: Praetorius, F. M., & Dietz, H. (2017). Self-assembly of genetically encoded
DNA-protein hybrid nanoscale shapes. Science. American Association for
the Advancement of Science. https://doi.org/10.1126/science.aam5488
chicago: Praetorius, Florian M, and Hendrik Dietz. “Self-Assembly of Genetically
Encoded DNA-Protein Hybrid Nanoscale Shapes.” Science. American Association
for the Advancement of Science, 2017. https://doi.org/10.1126/science.aam5488.
ieee: F. M. Praetorius and H. Dietz, “Self-assembly of genetically encoded DNA-protein
hybrid nanoscale shapes,” Science, vol. 355, no. 6331. American Association
for the Advancement of Science, 2017.
ista: Praetorius FM, Dietz H. 2017. Self-assembly of genetically encoded DNA-protein
hybrid nanoscale shapes. Science. 355(6331), eaam5488.
mla: Praetorius, Florian M., and Hendrik Dietz. “Self-Assembly of Genetically Encoded
DNA-Protein Hybrid Nanoscale Shapes.” Science, vol. 355, no. 6331, eaam5488,
American Association for the Advancement of Science, 2017, doi:10.1126/science.aam5488.
short: F.M. Praetorius, H. Dietz, Science 355 (2017).
date_created: 2023-09-06T12:08:55Z
date_published: 2017-03-24T00:00:00Z
date_updated: 2023-11-07T12:33:05Z
day: '24'
doi: 10.1126/science.aam5488
extern: '1'
external_id:
pmid:
- '28336611'
intvolume: ' 355'
issue: '6331'
language:
- iso: eng
month: '03'
oa_version: None
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 355
year: '2017'
...
---
_id: '15156'
abstract:
- lang: eng
text: Circadian clocks are ubiquitous timing systems that induce rhythms of biological
activities in synchrony with night and day. In cyanobacteria, timing is generated
by a posttranslational clock consisting of KaiA, KaiB, and KaiC proteins and a
set of output signaling proteins, SasA and CikA, which transduce this rhythm to
control gene expression. Here, we describe crystal and nuclear magnetic resonance
structures of KaiB-KaiC,KaiA-KaiB-KaiC, and CikA-KaiB complexes. They reveal how
the metamorphic properties of KaiB, a protein that adopts two distinct folds,
and the post–adenosine triphosphate hydrolysis state of KaiC create a hub around
which nighttime signaling events revolve, including inactivation of KaiA and reciprocal
regulation of the mutually antagonistic signaling proteins, SasA and CikA.
article_processing_charge: No
article_type: original
author:
- first_name: Roger
full_name: Tseng, Roger
last_name: Tseng
- first_name: Nicolette F.
full_name: Goularte, Nicolette F.
last_name: Goularte
- first_name: Archana
full_name: Chavan, Archana
last_name: Chavan
- first_name: Jansen
full_name: Luu, Jansen
last_name: Luu
- first_name: Susan E.
full_name: Cohen, Susan E.
last_name: Cohen
- first_name: Yong-Gang
full_name: Chang, Yong-Gang
last_name: Chang
- first_name: Joel
full_name: Heisler, Joel
last_name: Heisler
- first_name: Sheng
full_name: Li, Sheng
last_name: Li
- first_name: Alicia Kathleen
full_name: Michael, Alicia Kathleen
id: 6437c950-2a03-11ee-914d-d6476dd7b75c
last_name: Michael
- first_name: Sarvind
full_name: Tripathi, Sarvind
last_name: Tripathi
- first_name: Susan S.
full_name: Golden, Susan S.
last_name: Golden
- first_name: Andy
full_name: LiWang, Andy
last_name: LiWang
- first_name: Carrie L.
full_name: Partch, Carrie L.
last_name: Partch
citation:
ama: Tseng R, Goularte NF, Chavan A, et al. Structural basis of the day-night transition
in a bacterial circadian clock. Science. 2017;355(6330):1174-1180. doi:10.1126/science.aag2516
apa: Tseng, R., Goularte, N. F., Chavan, A., Luu, J., Cohen, S. E., Chang, Y.-G.,
… Partch, C. L. (2017). Structural basis of the day-night transition in a bacterial
circadian clock. Science. American Association for the Advancement of Science.
https://doi.org/10.1126/science.aag2516
chicago: Tseng, Roger, Nicolette F. Goularte, Archana Chavan, Jansen Luu, Susan
E. Cohen, Yong-Gang Chang, Joel Heisler, et al. “Structural Basis of the Day-Night
Transition in a Bacterial Circadian Clock.” Science. American Association
for the Advancement of Science, 2017. https://doi.org/10.1126/science.aag2516.
ieee: R. Tseng et al., “Structural basis of the day-night transition in a
bacterial circadian clock,” Science, vol. 355, no. 6330. American Association
for the Advancement of Science, pp. 1174–1180, 2017.
ista: Tseng R, Goularte NF, Chavan A, Luu J, Cohen SE, Chang Y-G, Heisler J, Li
S, Michael AK, Tripathi S, Golden SS, LiWang A, Partch CL. 2017. Structural basis
of the day-night transition in a bacterial circadian clock. Science. 355(6330),
1174–1180.
mla: Tseng, Roger, et al. “Structural Basis of the Day-Night Transition in a Bacterial
Circadian Clock.” Science, vol. 355, no. 6330, American Association for
the Advancement of Science, 2017, pp. 1174–80, doi:10.1126/science.aag2516.
short: R. Tseng, N.F. Goularte, A. Chavan, J. Luu, S.E. Cohen, Y.-G. Chang, J. Heisler,
S. Li, A.K. Michael, S. Tripathi, S.S. Golden, A. LiWang, C.L. Partch, Science
355 (2017) 1174–1180.
date_created: 2024-03-21T07:56:24Z
date_published: 2017-03-17T00:00:00Z
date_updated: 2024-03-25T12:16:44Z
day: '17'
doi: 10.1126/science.aag2516
extern: '1'
intvolume: ' 355'
issue: '6330'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '03'
oa_version: None
page: 1174-1180
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural basis of the day-night transition in a bacterial circadian clock
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 355
year: '2017'
...
---
_id: '611'
abstract:
- lang: eng
text: Small RNAs (sRNAs) regulate genes in plants and animals. Here, we show that
population-wide differences in color patterns in snapdragon flowers are caused
by an inverted duplication that generates sRNAs. The complexity and size of the
transcripts indicate that the duplication represents an intermediate on the pathway
to microRNA evolution. The sRNAs repress a pigment biosynthesis gene, creating
a yellow highlight at the site of pollinator entry. The inverted duplication exhibits
steep clines in allele frequency in a natural hybrid zone, showing that the allele
is under selection. Thus, regulatory interactions of evolutionarily recent sRNAs
can be acted upon by selection and contribute to the evolution of phenotypic diversity.
article_processing_charge: No
author:
- first_name: Desmond
full_name: Bradley, Desmond
last_name: Bradley
- first_name: Ping
full_name: Xu, Ping
last_name: Xu
- first_name: Irina
full_name: Mohorianu, Irina
last_name: Mohorianu
- first_name: Annabel
full_name: Whibley, Annabel
last_name: Whibley
- first_name: David
full_name: Field, David
id: 419049E2-F248-11E8-B48F-1D18A9856A87
last_name: Field
orcid: 0000-0002-4014-8478
- first_name: Hugo
full_name: Tavares, Hugo
last_name: Tavares
- first_name: Matthew
full_name: Couchman, Matthew
last_name: Couchman
- first_name: Lucy
full_name: Copsey, Lucy
last_name: Copsey
- first_name: Rosemary
full_name: Carpenter, Rosemary
last_name: Carpenter
- first_name: Miaomiao
full_name: Li, Miaomiao
last_name: Li
- first_name: Qun
full_name: Li, Qun
last_name: Li
- first_name: Yongbiao
full_name: Xue, Yongbiao
last_name: Xue
- first_name: Tamas
full_name: Dalmay, Tamas
last_name: Dalmay
- first_name: Enrico
full_name: Coen, Enrico
last_name: Coen
citation:
ama: Bradley D, Xu P, Mohorianu I, et al. Evolution of flower color pattern through
selection on regulatory small RNAs. Science. 2017;358(6365):925-928. doi:10.1126/science.aao3526
apa: Bradley, D., Xu, P., Mohorianu, I., Whibley, A., Field, D., Tavares, H., …
Coen, E. (2017). Evolution of flower color pattern through selection on regulatory
small RNAs. Science. American Association for the Advancement of Science.
https://doi.org/10.1126/science.aao3526
chicago: Bradley, Desmond, Ping Xu, Irina Mohorianu, Annabel Whibley, David Field,
Hugo Tavares, Matthew Couchman, et al. “Evolution of Flower Color Pattern through
Selection on Regulatory Small RNAs.” Science. American Association for
the Advancement of Science, 2017. https://doi.org/10.1126/science.aao3526.
ieee: D. Bradley et al., “Evolution of flower color pattern through selection
on regulatory small RNAs,” Science, vol. 358, no. 6365. American Association
for the Advancement of Science, pp. 925–928, 2017.
ista: Bradley D, Xu P, Mohorianu I, Whibley A, Field D, Tavares H, Couchman M, Copsey
L, Carpenter R, Li M, Li Q, Xue Y, Dalmay T, Coen E. 2017. Evolution of flower
color pattern through selection on regulatory small RNAs. Science. 358(6365),
925–928.
mla: Bradley, Desmond, et al. “Evolution of Flower Color Pattern through Selection
on Regulatory Small RNAs.” Science, vol. 358, no. 6365, American Association
for the Advancement of Science, 2017, pp. 925–28, doi:10.1126/science.aao3526.
short: D. Bradley, P. Xu, I. Mohorianu, A. Whibley, D. Field, H. Tavares, M. Couchman,
L. Copsey, R. Carpenter, M. Li, Q. Li, Y. Xue, T. Dalmay, E. Coen, Science 358
(2017) 925–928.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-11-17T00:00:00Z
date_updated: 2025-09-11T07:34:49Z
day: '17'
department:
- _id: NiBa
doi: 10.1126/science.aao3526
external_id:
isi:
- '000415293000047'
intvolume: ' 358'
isi: 1
issue: '6365'
language:
- iso: eng
month: '11'
oa_version: None
page: 925 - 928
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7193'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolution of flower color pattern through selection on regulatory small RNAs
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 358
year: '2017'
...
---
_id: '18198'
abstract:
- lang: eng
text: Higgs and Goldstone modes are collective excitations of the amplitude and
phase of an order parameter that is related to the breaking of a continuous symmetry.
We directly studied these modes in a supersolid quantum gas created by coupling
a Bose-Einstein condensate to two optical cavities, whose field amplitudes form
the real and imaginary parts of a U(1)-symmetric order parameter. Monitoring the
cavity fields in real time allowed us to observe the dynamics of the associated
Higgs and Goldstone modes and revealed their amplitude and phase nature. We used
a spectroscopic method to measure their frequencies, and we gave a tunable mass
to the Goldstone mode by exploring the crossover between continuous and discrete
symmetry. Our experiments link spectroscopic measurements to the theoretical concept
of Higgs and Goldstone modes.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Julian
full_name: Leonard, Julian
id: b75b3f45-7995-11ef-9bfd-9a9cd02c3577
last_name: Leonard
- first_name: Andrea
full_name: Morales, Andrea
last_name: Morales
- first_name: Philip
full_name: Zupancic, Philip
last_name: Zupancic
- first_name: Tobias
full_name: Donner, Tobias
last_name: Donner
- first_name: Tilman
full_name: Esslinger, Tilman
last_name: Esslinger
citation:
ama: Leonard J, Morales A, Zupancic P, Donner T, Esslinger T. Monitoring and manipulating
Higgs and Goldstone modes in a supersolid quantum gas. Science. 2017;358(6369):1415-1418.
doi:10.1126/science.aan2608
apa: Leonard, J., Morales, A., Zupancic, P., Donner, T., & Esslinger, T. (2017).
Monitoring and manipulating Higgs and Goldstone modes in a supersolid quantum
gas. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aan2608
chicago: Leonard, Julian, Andrea Morales, Philip Zupancic, Tobias Donner, and Tilman
Esslinger. “Monitoring and Manipulating Higgs and Goldstone Modes in a Supersolid
Quantum Gas.” Science. American Association for the Advancement of Science,
2017. https://doi.org/10.1126/science.aan2608.
ieee: J. Leonard, A. Morales, P. Zupancic, T. Donner, and T. Esslinger, “Monitoring
and manipulating Higgs and Goldstone modes in a supersolid quantum gas,” Science,
vol. 358, no. 6369. American Association for the Advancement of Science, pp. 1415–1418,
2017.
ista: Leonard J, Morales A, Zupancic P, Donner T, Esslinger T. 2017. Monitoring
and manipulating Higgs and Goldstone modes in a supersolid quantum gas. Science.
358(6369), 1415–1418.
mla: Leonard, Julian, et al. “Monitoring and Manipulating Higgs and Goldstone Modes
in a Supersolid Quantum Gas.” Science, vol. 358, no. 6369, American Association
for the Advancement of Science, 2017, pp. 1415–18, doi:10.1126/science.aan2608.
short: J. Leonard, A. Morales, P. Zupancic, T. Donner, T. Esslinger, Science 358
(2017) 1415–1418.
date_created: 2024-10-07T11:49:27Z
date_published: 2017-12-15T00:00:00Z
date_updated: 2024-10-07T12:12:46Z
day: '15'
doi: 10.1126/science.aan2608
extern: '1'
external_id:
pmid:
- '29242343'
intvolume: ' 358'
issue: '6369'
language:
- iso: eng
month: '12'
oa_version: None
page: 1415-1418
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Monitoring and manipulating Higgs and Goldstone modes in a supersolid quantum
gas
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 358
year: '2017'
...
---
_id: '943'
abstract:
- lang: eng
text: Like many developing tissues, the vertebrate neural tube is patterned by antiparallel
morphogen gradients. To understand how these inputs are interpreted, we measured
morphogen signaling and target gene expression in mouse embryos and chick ex vivo
assays. From these data, we derived and validated a characteristic decoding map
that relates morphogen input to the positional identity of neural progenitors.
Analysis of the observed responses indicates that the underlying interpretation
strategy minimizes patterning errors in response to the joint input of noisy opposing
gradients. We reverse-engineered a transcriptional network that provides a mechanistic
basis for the observed cell fate decisions and accounts for the precision and
dynamics of pattern formation. Together, our data link opposing gradient dynamics
in a growing tissue to precise pattern formation.
article_processing_charge: No
author:
- first_name: Marcin P
full_name: Zagórski, Marcin P
id: 343DA0DC-F248-11E8-B48F-1D18A9856A87
last_name: Zagórski
orcid: 0000-0001-7896-7762
- first_name: Yoji
full_name: Tabata, Yoji
last_name: Tabata
- first_name: Nathalie
full_name: Brandenberg, Nathalie
last_name: Brandenberg
- first_name: Matthias
full_name: Lutolf, Matthias
last_name: Lutolf
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Tobias
full_name: Bollenbach, Tobias
last_name: Bollenbach
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Anna
full_name: Kicheva, Anna
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
citation:
ama: Zagórski MP, Tabata Y, Brandenberg N, et al. Decoding of position in the developing
neural tube from antiparallel morphogen gradients. Science. 2017;356(6345):1379-1383.
doi:10.1126/science.aam5887
apa: Zagórski, M. P., Tabata, Y., Brandenberg, N., Lutolf, M., Tkačik, G., Bollenbach,
T., … Kicheva, A. (2017). Decoding of position in the developing neural tube from
antiparallel morphogen gradients. Science. American Association for the
Advancement of Science. https://doi.org/10.1126/science.aam5887
chicago: Zagórski, Marcin P, Yoji Tabata, Nathalie Brandenberg, Matthias Lutolf,
Gašper Tkačik, Tobias Bollenbach, James Briscoe, and Anna Kicheva. “Decoding of
Position in the Developing Neural Tube from Antiparallel Morphogen Gradients.”
Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aam5887.
ieee: M. P. Zagórski et al., “Decoding of position in the developing neural
tube from antiparallel morphogen gradients,” Science, vol. 356, no. 6345.
American Association for the Advancement of Science, pp. 1379–1383, 2017.
ista: Zagórski MP, Tabata Y, Brandenberg N, Lutolf M, Tkačik G, Bollenbach T, Briscoe
J, Kicheva A. 2017. Decoding of position in the developing neural tube from antiparallel
morphogen gradients. Science. 356(6345), 1379–1383.
mla: Zagórski, Marcin P., et al. “Decoding of Position in the Developing Neural
Tube from Antiparallel Morphogen Gradients.” Science, vol. 356, no. 6345,
American Association for the Advancement of Science, 2017, pp. 1379–83, doi:10.1126/science.aam5887.
short: M.P. Zagórski, Y. Tabata, N. Brandenberg, M. Lutolf, G. Tkačik, T. Bollenbach,
J. Briscoe, A. Kicheva, Science 356 (2017) 1379–1383.
corr_author: '1'
date_created: 2018-12-11T11:49:20Z
date_published: 2017-06-30T00:00:00Z
date_updated: 2025-07-10T12:01:45Z
day: '30'
department:
- _id: AnKi
- _id: GaTk
doi: 10.1126/science.aam5887
ec_funded: 1
external_id:
isi:
- '000404351500036'
pmid:
- '28663499'
intvolume: ' 356'
isi: 1
issue: '6345'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568706/
month: '06'
oa: 1
oa_version: Submitted Version
page: 1379 - 1383
pmid: 1
project:
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
- _id: B6FC0238-B512-11E9-945C-1524E6697425
call_identifier: H2020
grant_number: '680037'
name: Coordination of Patterning And Growth In the Spinal Cord
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 2524F500-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '201439'
name: Developing High-Throughput Bioassays for Human Cancers in Zebrafish
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '6474'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Decoding of position in the developing neural tube from antiparallel morphogen
gradients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 356
year: '2017'
...
---
_id: '665'
abstract:
- lang: eng
text: The molecular mechanisms underlying phenotypic variation in isogenic bacterial
populations remain poorly understood.We report that AcrAB-TolC, the main multidrug
efflux pump of Escherichia coli, exhibits a strong partitioning bias for old cell
poles by a segregation mechanism that is mediated by ternary AcrAB-TolC complex
formation. Mother cells inheriting old poles are phenotypically distinct and display
increased drug efflux activity relative to daughters. Consequently, we find systematic
and long-lived growth differences between mother and daughter cells in the presence
of subinhibitory drug concentrations. A simple model for biased partitioning predicts
a population structure of long-lived and highly heterogeneous phenotypes. This
straightforward mechanism of generating sustained growth rate differences at subinhibitory
antibiotic concentrations has implications for understanding the emergence of
multidrug resistance in bacteria.
article_processing_charge: No
article_type: original
author:
- first_name: Tobias
full_name: Bergmiller, Tobias
id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
last_name: Bergmiller
orcid: 0000-0001-5396-4346
- first_name: Anna M
full_name: Andersson, Anna M
id: 2B8A40DA-F248-11E8-B48F-1D18A9856A87
last_name: Andersson
orcid: 0000-0003-2912-6769
- first_name: Kathrin
full_name: Tomasek, Kathrin
id: 3AEC8556-F248-11E8-B48F-1D18A9856A87
last_name: Tomasek
orcid: 0000-0003-3768-877X
- first_name: Enrique
full_name: Balleza, Enrique
last_name: Balleza
- first_name: Daniel
full_name: Kiviet, Daniel
last_name: Kiviet
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
citation:
ama: Bergmiller T, Andersson AM, Tomasek K, et al. Biased partitioning of the multidrug
efflux pump AcrAB TolC underlies long lived phenotypic heterogeneity. Science.
2017;356(6335):311-315. doi:10.1126/science.aaf4762
apa: Bergmiller, T., Andersson, A. M., Tomasek, K., Balleza, E., Kiviet, D., Hauschild,
R., … Guet, C. C. (2017). Biased partitioning of the multidrug efflux pump AcrAB
TolC underlies long lived phenotypic heterogeneity. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.aaf4762
chicago: Bergmiller, Tobias, Anna M Andersson, Kathrin Tomasek, Enrique Balleza,
Daniel Kiviet, Robert Hauschild, Gašper Tkačik, and Calin C Guet. “Biased Partitioning
of the Multidrug Efflux Pump AcrAB TolC Underlies Long Lived Phenotypic Heterogeneity.”
Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aaf4762.
ieee: T. Bergmiller et al., “Biased partitioning of the multidrug efflux
pump AcrAB TolC underlies long lived phenotypic heterogeneity,” Science,
vol. 356, no. 6335. American Association for the Advancement of Science, pp. 311–315,
2017.
ista: Bergmiller T, Andersson AM, Tomasek K, Balleza E, Kiviet D, Hauschild R, Tkačik
G, Guet CC. 2017. Biased partitioning of the multidrug efflux pump AcrAB TolC
underlies long lived phenotypic heterogeneity. Science. 356(6335), 311–315.
mla: Bergmiller, Tobias, et al. “Biased Partitioning of the Multidrug Efflux Pump
AcrAB TolC Underlies Long Lived Phenotypic Heterogeneity.” Science, vol.
356, no. 6335, American Association for the Advancement of Science, 2017, pp.
311–15, doi:10.1126/science.aaf4762.
short: T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild,
G. Tkačik, C.C. Guet, Science 356 (2017) 311–315.
corr_author: '1'
date_created: 2018-12-11T11:47:48Z
date_published: 2017-04-21T00:00:00Z
date_updated: 2025-09-11T07:05:04Z
day: '21'
department:
- _id: CaGu
- _id: GaTk
- _id: Bio
doi: 10.1126/science.aaf4762
external_id:
isi:
- '000399540100060'
intvolume: ' 356'
isi: 1
issue: '6335'
language:
- iso: eng
month: '04'
oa_version: None
page: 311 - 315
project:
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7064'
quality_controlled: '1'
related_material:
record:
- id: '5560'
relation: popular_science
status: public
scopus_import: '1'
status: public
title: Biased partitioning of the multidrug efflux pump AcrAB TolC underlies long
lived phenotypic heterogeneity
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 356
year: '2017'
...
---
OA_place: repository
OA_type: green
_id: '587'
abstract:
- lang: eng
text: Quantum metrology exploits entangled states of particles to improve sensing
precision beyond the limit achievable with uncorrelated particles. All previous
methods required detection noise levels below this standard quantum limit to realize
the benefits of the intrinsic sensitivity provided by these states.We experimentally
demonstrate a widely applicable method for entanglement-enhanced measurements
without low-noise detection. The method involves an intermediate quantum phase
magnification step that eases implementation complexity. We used it to perform
squeezed-state metrology 8 decibels below the standard quantum limit with a detection
system that has a noise floor 10 decibels above the standard quantum limit.
article_processing_charge: No
arxiv: 1
author:
- first_name: Onur
full_name: Hosten, Onur
id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
last_name: Hosten
orcid: 0000-0002-2031-204X
- first_name: Rajiv
full_name: Krishnakumar, Rajiv
last_name: Krishnakumar
- first_name: Nils
full_name: Engelsen, Nils
last_name: Engelsen
- first_name: Mark
full_name: Kasevich, Mark
last_name: Kasevich
citation:
ama: Hosten O, Krishnakumar R, Engelsen N, Kasevich M. Quantum Phase Magnification.
Vol 352. American Association for the Advancement of Science; 2016:1552-1555.
doi:10.1126/science.aaf3397
apa: Hosten, O., Krishnakumar, R., Engelsen, N., & Kasevich, M. (2016). Quantum
phase magnification (Vol. 352, pp. 1552–1555). American Association for the
Advancement of Science. https://doi.org/10.1126/science.aaf3397
chicago: Hosten, Onur, Rajiv Krishnakumar, Nils Engelsen, and Mark Kasevich. Quantum
Phase Magnification. Vol. 352. American Association for the Advancement of
Science, 2016. https://doi.org/10.1126/science.aaf3397.
ieee: O. Hosten, R. Krishnakumar, N. Engelsen, and M. Kasevich, Quantum phase
magnification, vol. 352. American Association for the Advancement of Science,
2016, pp. 1552–1555.
ista: Hosten O, Krishnakumar R, Engelsen N, Kasevich M. 2016. Quantum phase magnification,
American Association for the Advancement of Science,p.
mla: Hosten, Onur, et al. Quantum Phase Magnification. Vol. 352, American
Association for the Advancement of Science, 2016, pp. 1552–55, doi:10.1126/science.aaf3397.
short: O. Hosten, R. Krishnakumar, N. Engelsen, M. Kasevich, Quantum Phase Magnification,
American Association for the Advancement of Science, 2016.
date_created: 2018-12-11T11:47:21Z
date_published: 2016-06-24T00:00:00Z
date_updated: 2026-05-20T07:21:32Z
day: '24'
doi: 10.1126/science.aaf3397
extern: '1'
external_id:
arxiv:
- '1601.07683'
pmid:
- '27339982'
intvolume: ' 352'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.1601.07683'
month: '06'
oa: 1
oa_version: Preprint
page: 1552 - 1555
pmid: 1
publication_identifier:
eisbn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7214'
status: public
title: Quantum phase magnification
type: report
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 352
year: '2016'
...
---
_id: '816'
abstract:
- lang: eng
text: Immature HIV-1 assembles at and buds from the plasma membrane before proteolytic
cleavage of the viral Gag polyprotein induces structural maturation. Maturation
can be blocked by maturation inhibitors (MIs), thereby abolishing infectivity.
The CA (capsid) and SP1 (spacer peptide 1) region of Gag is the key regulator
of assembly and maturation and is the target of MIs.We applied optimized cryo-electron
tomography and subtomogram averaging to resolve this region within assembled immature
HIV-1 particles at 3.9 angstrom resolution and built an atomic model. The structure
reveals a network of intra- And intermolecular interactions mediating immature
HIV-1 assembly. The proteolytic cleavage site between CA and SP1 is inaccessible
to protease.We suggest that MIs prevent CA-SP1 cleavage by stabilizing the structure,
and MI resistance develops by destabilizing CA-SP1.
acknowledgement: The authors thank B. Glass for preparation of the immature HIV-1
(D25A) sample; J. Plitzko and D. Tegunov for providing the K2Align software; and
S. Mattei, N. Hoffman, F. Thommen, A. Sonnen, and S. Dodonova for technical assistance
and/or discussion. This study was supported by Deutsche Forschungsgemeinschaft grants
BR 3635/2-1 (to J.A.G.B.) and KR 906/7-1 (to H.-G.K.). The Briggs laboratory acknowledges
financial support from the European Molecular Biology Laboratory (EMBL) and from
the Chica und Heinz Schaller Stiftung. W.W. was supported by a European Molecular
Biology Organization Long-Term Fellowship (ALTF 748-2014). A.J.J. acknowledges support
by the EMBL Interdisciplinary Postdoc Program under the Marie Curie Action COFUND
(PCOFUND-GA-2008-229597) and by the Joachim Herz Stiftung. This study was technically
supported by the EMBL information technology services unit and the EMBL Proteomics
Core Facility. F.K.M.S., M.O., H.-G.K., and J.A.G.B. designed the experiments, with
J.M.K. assisting in the design of those involving mass spectrometry. F.K.M.S. and
M.O. prepared samples. W.J.H.H. implemented tomography acquisition schemes. F.K.M.S.
and W.J.H.H. acquired the data. F.K.M.S. and W.W. processed images. F.K.M.S., A.J.J.,
and C.S. refined the model. F.K.M.S., M.O., and J.A.G.B. analyzed the data. F.K.M.S.
and J.A.G.B. wrote the manuscript with support from all authors. Representative
tomograms and the final electron microscopy structures have been deposited in the
Electron Microscopy Data Bank with accession numbers EMD-4015, EMD-4016, EMD-4017,
EMD-4018, EMD-4019, and EMD-4020. The refined HIV-1 CA-SP1 model has been deposited
in the Protein Data Bank with accession number 5L93.
article_processing_charge: No
author:
- first_name: Florian
full_name: Schur, Florian
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Martin
full_name: Obr, Martin
id: 4741CA5A-F248-11E8-B48F-1D18A9856A87
last_name: Obr
orcid: 0000-0003-1756-6564
- first_name: Wim
full_name: Hagen, Wim
last_name: Hagen
- first_name: William
full_name: Wan, William
last_name: Wan
- first_name: Arjen
full_name: Jakobi, Arjen
last_name: Jakobi
- first_name: Joanna
full_name: Kirkpatrick, Joanna
last_name: Kirkpatrick
- first_name: Carsten
full_name: Sachse, Carsten
last_name: Sachse
- first_name: Hans
full_name: Kraüsslich, Hans
last_name: Kraüsslich
- first_name: John
full_name: Briggs, John
last_name: Briggs
citation:
ama: Schur FK, Obr M, Hagen W, et al. An Atomic Model of HIV-1 Capsid-SP1 Reveals
Structures Regulating Assembly and Maturation. Vol 353. American Association
for the Advancement of Science; 2016:506-508. doi:10.1126/science.aaf9620
apa: Schur, F. K., Obr, M., Hagen, W., Wan, W., Jakobi, A., Kirkpatrick, J., … Briggs,
J. (2016). An atomic model of HIV-1 capsid-SP1 reveals structures regulating
assembly and maturation (Vol. 353, pp. 506–508). American Association for
the Advancement of Science. https://doi.org/10.1126/science.aaf9620
chicago: Schur, Florian KM, Martin Obr, Wim Hagen, William Wan, Arjen Jakobi, Joanna
Kirkpatrick, Carsten Sachse, Hans Kraüsslich, and John Briggs. An Atomic Model
of HIV-1 Capsid-SP1 Reveals Structures Regulating Assembly and Maturation.
Vol. 353. American Association for the Advancement of Science, 2016. https://doi.org/10.1126/science.aaf9620.
ieee: F. K. Schur et al., An atomic model of HIV-1 capsid-SP1 reveals
structures regulating assembly and maturation, vol. 353. American Association
for the Advancement of Science, 2016, pp. 506–508.
ista: Schur FK, Obr M, Hagen W, Wan W, Jakobi A, Kirkpatrick J, Sachse C, Kraüsslich
H, Briggs J. 2016. An atomic model of HIV-1 capsid-SP1 reveals structures regulating
assembly and maturation, American Association for the Advancement of Science,p.
mla: Schur, Florian KM, et al. An Atomic Model of HIV-1 Capsid-SP1 Reveals Structures
Regulating Assembly and Maturation. Vol. 353, American Association for the
Advancement of Science, 2016, pp. 506–08, doi:10.1126/science.aaf9620.
short: F.K. Schur, M. Obr, W. Hagen, W. Wan, A. Jakobi, J. Kirkpatrick, C. Sachse,
H. Kraüsslich, J. Briggs, An Atomic Model of HIV-1 Capsid-SP1 Reveals Structures
Regulating Assembly and Maturation, American Association for the Advancement of
Science, 2016.
date_created: 2018-12-11T11:48:39Z
date_published: 2016-07-29T00:00:00Z
date_updated: 2026-05-20T07:41:16Z
day: '29'
doi: 10.1126/science.aaf9620
extern: '1'
external_id:
pmid:
- '27417497'
intvolume: ' 353'
language:
- iso: eng
month: '07'
oa_version: None
page: 506 - 508
pmid: 1
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '6834'
scopus_import: '1'
status: public
title: An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly
and maturation
type: report
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 353
year: '2016'
...
---
_id: '14013'
abstract:
- lang: eng
text: The ultrafast motion of electrons and holes after light-matter interaction
is fundamental to a broad range of chemical and biophysical processes. We advanced
high-harmonic spectroscopy to resolve spatially and temporally the migration of
an electron hole immediately after ionization of iodoacetylene while simultaneously
demonstrating extensive control over the process. A multidimensional approach,
based on the measurement and accurate theoretical description of both even and
odd harmonic orders, enabled us to reconstruct both quantum amplitudes and phases
of the electronic states with a resolution of ~100 attoseconds. We separately
reconstructed quasi-field-free and laser-controlled charge migration as a function
of the spatial orientation of the molecule and determined the shape of the hole
created by ionization. Our technique opens the prospect of laser control over
electronic primary processes.
article_processing_charge: No
article_type: original
author:
- first_name: P. M.
full_name: Kraus, P. M.
last_name: Kraus
- first_name: B.
full_name: Mignolet, B.
last_name: Mignolet
- first_name: Denitsa Rangelova
full_name: Baykusheva, Denitsa Rangelova
id: 71b4d059-2a03-11ee-914d-dfa3beed6530
last_name: Baykusheva
- first_name: A.
full_name: Rupenyan, A.
last_name: Rupenyan
- first_name: L.
full_name: Horný, L.
last_name: Horný
- first_name: E. F.
full_name: Penka, E. F.
last_name: Penka
- first_name: G.
full_name: Grassi, G.
last_name: Grassi
- first_name: O. I.
full_name: Tolstikhin, O. I.
last_name: Tolstikhin
- first_name: J.
full_name: Schneider, J.
last_name: Schneider
- first_name: F.
full_name: Jensen, F.
last_name: Jensen
- first_name: L. B.
full_name: Madsen, L. B.
last_name: Madsen
- first_name: A. D.
full_name: Bandrauk, A. D.
last_name: Bandrauk
- first_name: F.
full_name: Remacle, F.
last_name: Remacle
- first_name: H. J.
full_name: Wörner, H. J.
last_name: Wörner
citation:
ama: Kraus PM, Mignolet B, Baykusheva DR, et al. Measurement and laser control of
attosecond charge migration in ionized iodoacetylene. Science. 2015;350(6262):790-795.
doi:10.1126/science.aab2160
apa: Kraus, P. M., Mignolet, B., Baykusheva, D. R., Rupenyan, A., Horný, L., Penka,
E. F., … Wörner, H. J. (2015). Measurement and laser control of attosecond charge
migration in ionized iodoacetylene. Science. American Association for the
Advancement of Science. https://doi.org/10.1126/science.aab2160
chicago: Kraus, P. M., B. Mignolet, Denitsa Rangelova Baykusheva, A. Rupenyan, L.
Horný, E. F. Penka, G. Grassi, et al. “Measurement and Laser Control of Attosecond
Charge Migration in Ionized Iodoacetylene.” Science. American Association
for the Advancement of Science, 2015. https://doi.org/10.1126/science.aab2160.
ieee: P. M. Kraus et al., “Measurement and laser control of attosecond charge
migration in ionized iodoacetylene,” Science, vol. 350, no. 6262. American
Association for the Advancement of Science, pp. 790–795, 2015.
ista: Kraus PM, Mignolet B, Baykusheva DR, Rupenyan A, Horný L, Penka EF, Grassi
G, Tolstikhin OI, Schneider J, Jensen F, Madsen LB, Bandrauk AD, Remacle F, Wörner
HJ. 2015. Measurement and laser control of attosecond charge migration in ionized
iodoacetylene. Science. 350(6262), 790–795.
mla: Kraus, P. M., et al. “Measurement and Laser Control of Attosecond Charge Migration
in Ionized Iodoacetylene.” Science, vol. 350, no. 6262, American Association
for the Advancement of Science, 2015, pp. 790–95, doi:10.1126/science.aab2160.
short: P.M. Kraus, B. Mignolet, D.R. Baykusheva, A. Rupenyan, L. Horný, E.F. Penka,
G. Grassi, O.I. Tolstikhin, J. Schneider, F. Jensen, L.B. Madsen, A.D. Bandrauk,
F. Remacle, H.J. Wörner, Science 350 (2015) 790–795.
date_created: 2023-08-10T06:37:35Z
date_published: 2015-10-22T00:00:00Z
date_updated: 2023-08-22T08:47:39Z
day: '22'
doi: 10.1126/science.aab2160
extern: '1'
external_id:
pmid:
- '26494175'
intvolume: ' 350'
issue: '6262'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '10'
oa_version: None
page: 790-795
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Measurement and laser control of attosecond charge migration in ionized iodoacetylene
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 350
year: '2015'
...
---
_id: '2229'
abstract:
- lang: eng
text: The distance between Ca^2+ channels and release sensors determines the speed
and efficacy of synaptic transmission. Tight "nanodomain" channel-sensor
coupling initiates transmitter release at synapses in the mature brain, whereas
loose "microdomain" coupling appears restricted to early developmental
stages. To probe the coupling configuration at a plastic synapse in the mature
central nervous system, we performed paired recordings between mossy fiber terminals
and CA3 pyramidal neurons in rat hippocampus. Millimolar concentrations of both
the fast Ca^2+ chelator BAPTA [1,2-bis(2-aminophenoxy)ethane- N,N, N′,N′-tetraacetic
acid] and the slow chelator EGTA efficiently suppressed transmitter release, indicating
loose coupling between Ca^2+ channels and release sensors. Loose coupling enabled
the control of initial release probability by fast endogenous Ca^2+ buffers and
the generation of facilitation by buffer saturation. Thus, loose coupling provides
the molecular framework for presynaptic plasticity.
article_processing_charge: No
author:
- first_name: Nicholas
full_name: Vyleta, Nicholas
id: 36C4978E-F248-11E8-B48F-1D18A9856A87
last_name: Vyleta
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Vyleta N, Jonas PM. Loose coupling between Ca^2+ channels and release sensors
at a plastic hippocampal synapse. Science. 2014;343(6171):665-670. doi:10.1126/science.1244811
apa: Vyleta, N., & Jonas, P. M. (2014). Loose coupling between Ca^2+ channels
and release sensors at a plastic hippocampal synapse. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.1244811
chicago: Vyleta, Nicholas, and Peter M Jonas. “Loose Coupling between Ca^2+ Channels
and Release Sensors at a Plastic Hippocampal Synapse.” Science. American
Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1244811.
ieee: N. Vyleta and P. M. Jonas, “Loose coupling between Ca^2+ channels and release
sensors at a plastic hippocampal synapse,” Science, vol. 343, no. 6171.
American Association for the Advancement of Science, pp. 665–670, 2014.
ista: Vyleta N, Jonas PM. 2014. Loose coupling between Ca^2+ channels and release
sensors at a plastic hippocampal synapse. Science. 343(6171), 665–670.
mla: Vyleta, Nicholas, and Peter M. Jonas. “Loose Coupling between Ca^2+ Channels
and Release Sensors at a Plastic Hippocampal Synapse.” Science, vol. 343,
no. 6171, American Association for the Advancement of Science, 2014, pp. 665–70,
doi:10.1126/science.1244811.
short: N. Vyleta, P.M. Jonas, Science 343 (2014) 665–670.
corr_author: '1'
date_created: 2018-12-11T11:56:27Z
date_published: 2014-02-01T00:00:00Z
date_updated: 2025-09-29T11:24:38Z
day: '01'
department:
- _id: PeJo
doi: 10.1126/science.1244811
ec_funded: 1
external_id:
isi:
- '000330724000044'
intvolume: ' 343'
isi: 1
issue: '6171'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617475/
month: '02'
oa: 1
oa_version: Submitted Version
page: 665 - 670
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P24909-B24
name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4732'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Loose coupling between Ca^2+ channels and release sensors at a plastic hippocampal
synapse
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 343
year: '2014'
...
---
_id: '13400'
abstract:
- lang: eng
text: Organizing inorganic nanocrystals into complex architectures is challenging
and typically relies on preexisting templates, such as properly folded DNA or
polypeptide chains. We found that under carefully controlled conditions, cubic
nanocrystals of magnetite self-assemble into arrays of helical superstructures
in a template-free manner with >99% yield. Computer simulations revealed that
the formation of helices is determined by the interplay of van der Waals and magnetic
dipole-dipole interactions, Zeeman coupling, and entropic forces and can be attributed
to spontaneous formation of chiral nanocube clusters. Neighboring helices within
their densely packed ensembles tended to adopt the same handedness in order to
maximize packing, thus revealing a novel mechanism of symmetry breaking and chirality
amplification.
article_processing_charge: No
article_type: original
author:
- first_name: Gurvinder
full_name: Singh, Gurvinder
last_name: Singh
- first_name: Henry
full_name: Chan, Henry
last_name: Chan
- first_name: Artem
full_name: Baskin, Artem
last_name: Baskin
- first_name: Elijah
full_name: Gelman, Elijah
last_name: Gelman
- first_name: Nikita
full_name: Repnin, Nikita
last_name: Repnin
- first_name: Petr
full_name: Král, Petr
last_name: Král
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Singh G, Chan H, Baskin A, et al. Self-assembly of magnetite nanocubes into
helical superstructures. Science. 2014;345(6201):1149-1153. doi:10.1126/science.1254132
apa: Singh, G., Chan, H., Baskin, A., Gelman, E., Repnin, N., Král, P., & Klajn,
R. (2014). Self-assembly of magnetite nanocubes into helical superstructures.
Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1254132
chicago: Singh, Gurvinder, Henry Chan, Artem Baskin, Elijah Gelman, Nikita Repnin,
Petr Král, and Rafal Klajn. “Self-Assembly of Magnetite Nanocubes into Helical
Superstructures.” Science. American Association for the Advancement of
Science, 2014. https://doi.org/10.1126/science.1254132.
ieee: G. Singh et al., “Self-assembly of magnetite nanocubes into helical
superstructures,” Science, vol. 345, no. 6201. American Association for
the Advancement of Science, pp. 1149–1153, 2014.
ista: Singh G, Chan H, Baskin A, Gelman E, Repnin N, Král P, Klajn R. 2014. Self-assembly
of magnetite nanocubes into helical superstructures. Science. 345(6201), 1149–1153.
mla: Singh, Gurvinder, et al. “Self-Assembly of Magnetite Nanocubes into Helical
Superstructures.” Science, vol. 345, no. 6201, American Association for
the Advancement of Science, 2014, pp. 1149–53, doi:10.1126/science.1254132.
short: G. Singh, H. Chan, A. Baskin, E. Gelman, N. Repnin, P. Král, R. Klajn, Science
345 (2014) 1149–1153.
date_created: 2023-08-01T09:45:56Z
date_published: 2014-07-24T00:00:00Z
date_updated: 2024-10-14T12:20:09Z
day: '24'
doi: 10.1126/science.1254132
extern: '1'
external_id:
pmid:
- '25061133'
intvolume: ' 345'
issue: '6201'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '07'
oa_version: None
page: 1149-1153
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Self-assembly of magnetite nanocubes into helical superstructures
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 345
year: '2014'
...
---
_id: '9055'
abstract:
- lang: eng
text: Spontaneous formation of colonies of bacteria or flocks of birds are examples
of self-organization in active living matter. Here, we demonstrate a form of self-organization
from nonequilibrium driving forces in a suspension of synthetic photoactivated
colloidal particles. They lead to two-dimensional "living crystals," which form,
break, explode, and re-form elsewhere. The dynamic assembly results from a competition
between self-propulsion of particles and an attractive interaction induced respectively
by osmotic and phoretic effects and activated by light. We measured a transition
from normal to giant-number fluctuations. Our experiments are quantitatively described
by simple numerical simulations. We show that the existence of the living crystals
is intrinsically related to the out-of-equilibrium collisions of the self-propelled
particles.
article_processing_charge: No
article_type: original
author:
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
- first_name: S.
full_name: Sacanna, S.
last_name: Sacanna
- first_name: A. P.
full_name: Steinberg, A. P.
last_name: Steinberg
- first_name: D. J.
full_name: Pine, D. J.
last_name: Pine
- first_name: P. M.
full_name: Chaikin, P. M.
last_name: Chaikin
citation:
ama: Palacci JA, Sacanna S, Steinberg AP, Pine DJ, Chaikin PM. Living crystals of
light-activated colloidal surfers. Science. 2013;339(6122):936-940. doi:10.1126/science.1230020
apa: Palacci, J. A., Sacanna, S., Steinberg, A. P., Pine, D. J., & Chaikin,
P. M. (2013). Living crystals of light-activated colloidal surfers. Science.
American Association for the Advancement of Science . https://doi.org/10.1126/science.1230020
chicago: Palacci, Jérémie A, S. Sacanna, A. P. Steinberg, D. J. Pine, and P. M.
Chaikin. “Living Crystals of Light-Activated Colloidal Surfers.” Science.
American Association for the Advancement of Science , 2013. https://doi.org/10.1126/science.1230020.
ieee: J. A. Palacci, S. Sacanna, A. P. Steinberg, D. J. Pine, and P. M. Chaikin,
“Living crystals of light-activated colloidal surfers,” Science, vol. 339,
no. 6122. American Association for the Advancement of Science , pp. 936–940, 2013.
ista: Palacci JA, Sacanna S, Steinberg AP, Pine DJ, Chaikin PM. 2013. Living crystals
of light-activated colloidal surfers. Science. 339(6122), 936–940.
mla: Palacci, Jérémie A., et al. “Living Crystals of Light-Activated Colloidal Surfers.”
Science, vol. 339, no. 6122, American Association for the Advancement of
Science , 2013, pp. 936–40, doi:10.1126/science.1230020.
short: J.A. Palacci, S. Sacanna, A.P. Steinberg, D.J. Pine, P.M. Chaikin, Science
339 (2013) 936–940.
date_created: 2021-02-01T14:37:29Z
date_published: 2013-02-22T00:00:00Z
date_updated: 2022-08-25T14:57:43Z
day: '22'
doi: 10.1126/science.1230020
extern: '1'
external_id:
pmid:
- '23371555'
intvolume: ' 339'
issue: '6122'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '02'
oa_version: None
page: 936-940
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: 'American Association for the Advancement of Science '
quality_controlled: '1'
scopus_import: '1'
status: public
title: Living crystals of light-activated colloidal surfers
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 339
year: '2013'
...
---
_id: '11092'
abstract:
- lang: eng
text: To combat the functional decline of the proteome, cells use the process of
protein turnover to replace potentially impaired polypeptides with new functional
copies. We found that extremely long-lived proteins (ELLPs) did not turn over
in postmitotic cells of the rat central nervous system. These ELLPs were associated
with chromatin and the nuclear pore complex, the central transport channels that
mediate all molecular trafficking in and out of the nucleus. The longevity of
these proteins would be expected to expose them to potentially harmful metabolites,
putting them at risk of accumulating damage over extended periods of time. Thus,
it is possible that failure to maintain proper levels and functional integrity
of ELLPs in nonproliferative cells might contribute to age-related deterioration
in cell and tissue function.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Jeffrey N.
full_name: Savas, Jeffrey N.
last_name: Savas
- first_name: Brandon H.
full_name: Toyama, Brandon H.
last_name: Toyama
- first_name: Tao
full_name: Xu, Tao
last_name: Xu
- first_name: John R.
full_name: Yates, John R.
last_name: Yates
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Savas JN, Toyama BH, Xu T, Yates JR, Hetzer M. Extremely long-lived nuclear
pore proteins in the rat brain. Science. 2012;335(6071):942-942. doi:10.1126/science.1217421
apa: Savas, J. N., Toyama, B. H., Xu, T., Yates, J. R., & Hetzer, M. (2012).
Extremely long-lived nuclear pore proteins in the rat brain. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.1217421
chicago: Savas, Jeffrey N., Brandon H. Toyama, Tao Xu, John R. Yates, and Martin
Hetzer. “Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain.” Science.
American Association for the Advancement of Science, 2012. https://doi.org/10.1126/science.1217421.
ieee: J. N. Savas, B. H. Toyama, T. Xu, J. R. Yates, and M. Hetzer, “Extremely long-lived
nuclear pore proteins in the rat brain,” Science, vol. 335, no. 6071. American
Association for the Advancement of Science, pp. 942–942, 2012.
ista: Savas JN, Toyama BH, Xu T, Yates JR, Hetzer M. 2012. Extremely long-lived
nuclear pore proteins in the rat brain. Science. 335(6071), 942–942.
mla: Savas, Jeffrey N., et al. “Extremely Long-Lived Nuclear Pore Proteins in the
Rat Brain.” Science, vol. 335, no. 6071, American Association for the Advancement
of Science, 2012, pp. 942–942, doi:10.1126/science.1217421.
short: J.N. Savas, B.H. Toyama, T. Xu, J.R. Yates, M. Hetzer, Science 335 (2012)
942–942.
date_created: 2022-04-07T07:52:01Z
date_published: 2012-02-02T00:00:00Z
date_updated: 2025-12-15T10:03:06Z
day: '02'
department:
- _id: MaHe
doi: 10.1126/science.1217421
extern: '1'
external_id:
pmid:
- '22300851'
intvolume: ' 335'
issue: '6071'
language:
- iso: eng
month: '02'
oa_version: None
page: 942-942
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extremely long-lived nuclear pore proteins in the rat brain
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 335
year: '2012'
...