---
OA_type: closed access
_id: '18878'
abstract:
- lang: eng
  text: Thermoelectric (TE) materials, with the ability to convert heat into electrical
    energy, can generate micro-electrical fields at electronic interfaces with biological
    systems, making them applicable in electric-catalyzing as nanozymes, and modulate
    the infected microenvironment of skin wounds. Thereby, by harnessing temperature
    differences in vitro or in vivo, TE nanomaterials can provide antimicrobial reactive
    oxygen species (ROS) by catalyzing redox reactions, thereby accelerating wound
    healing by suppressing infection. However, despite their promising potential,
    there is still a lack of comprehensive understanding of the antimicrobial mechanisms,
    biocompatibility, and practical applications of TE nanomaterials in wound healing,
    as this is a newly-emerged sub-area of energy-related biomedical applications.
    This review aims to address this gap by highlighting the emerging progress of
    TE materials in wound healing, clarifying their mechanism and advances, emphasizing
    their potential challenges for commercialization and clinical use, and proposing
    novel design strategies of TE nanomaterials for effective antibacterial performance.
acknowledgement: This work was financially supported by the Sichuan Science and Technology
  Program (Nos. 2023ZYD0064 and 2023YFG0220), the Fundamental Research Funds for the
  Central Universities (No. YJ202242), and the Research Funding from West China School/Hospital
  of Stomatology, Sichuan University (No. QDJF2022–2).
article_processing_charge: No
article_type: review
author:
- first_name: Shiyu
  full_name: Jia, Shiyu
  last_name: Jia
- first_name: Cai
  full_name: Qi, Cai
  last_name: Qi
- first_name: Shengduo
  full_name: Xu, Shengduo
  id: 12ab8624-4c8a-11ec-9e11-e1ac2438f22f
  last_name: Xu
- first_name: Lei
  full_name: Yang, Lei
  last_name: Yang
- first_name: Qiang
  full_name: Sun, Qiang
  last_name: Sun
citation:
  ama: Jia S, Qi C, Xu S, Yang L, Sun Q. Advancements of thermoelectric nanomaterials
    in ROS-mediated broad-spectrum antibacterial therapies for wound healing. <i>Journal
    of Materials Science and Technology</i>. 2025;225(08):212-226. doi:<a href="https://doi.org/10.1016/j.jmst.2024.11.039">10.1016/j.jmst.2024.11.039</a>
  apa: Jia, S., Qi, C., Xu, S., Yang, L., &#38; Sun, Q. (2025). Advancements of thermoelectric
    nanomaterials in ROS-mediated broad-spectrum antibacterial therapies for wound
    healing. <i>Journal of Materials Science and Technology</i>. Elsevier. <a href="https://doi.org/10.1016/j.jmst.2024.11.039">https://doi.org/10.1016/j.jmst.2024.11.039</a>
  chicago: Jia, Shiyu, Cai Qi, Shengduo Xu, Lei Yang, and Qiang Sun. “Advancements
    of Thermoelectric Nanomaterials in ROS-Mediated Broad-Spectrum Antibacterial Therapies
    for Wound Healing.” <i>Journal of Materials Science and Technology</i>. Elsevier,
    2025. <a href="https://doi.org/10.1016/j.jmst.2024.11.039">https://doi.org/10.1016/j.jmst.2024.11.039</a>.
  ieee: S. Jia, C. Qi, S. Xu, L. Yang, and Q. Sun, “Advancements of thermoelectric
    nanomaterials in ROS-mediated broad-spectrum antibacterial therapies for wound
    healing,” <i>Journal of Materials Science and Technology</i>, vol. 225, no. 08.
    Elsevier, pp. 212–226, 2025.
  ista: Jia S, Qi C, Xu S, Yang L, Sun Q. 2025. Advancements of thermoelectric nanomaterials
    in ROS-mediated broad-spectrum antibacterial therapies for wound healing. Journal
    of Materials Science and Technology. 225(08), 212–226.
  mla: Jia, Shiyu, et al. “Advancements of Thermoelectric Nanomaterials in ROS-Mediated
    Broad-Spectrum Antibacterial Therapies for Wound Healing.” <i>Journal of Materials
    Science and Technology</i>, vol. 225, no. 08, Elsevier, 2025, pp. 212–26, doi:<a
    href="https://doi.org/10.1016/j.jmst.2024.11.039">10.1016/j.jmst.2024.11.039</a>.
  short: S. Jia, C. Qi, S. Xu, L. Yang, Q. Sun, Journal of Materials Science and Technology
    225 (2025) 212–226.
date_created: 2025-01-26T23:01:49Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-12-30T07:19:04Z
day: '01'
department:
- _id: MaIb
doi: 10.1016/j.jmst.2024.11.039
external_id:
  isi:
  - '001407204300001'
intvolume: '       225'
isi: 1
issue: '08'
language:
- iso: eng
month: '08'
oa_version: None
page: 212-226
publication: Journal of Materials Science and Technology
publication_identifier:
  issn:
  - 1005-0302
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Advancements of thermoelectric nanomaterials in ROS-mediated broad-spectrum
  antibacterial therapies for wound healing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 225
year: '2025'
...
