@article{21103,
  abstract     = {The structure of the decadeoxyribonucleotide d(GCATGCATGC) is presented at a resolution of 1.8 Å. The decamer adopts a novel double-folded structure in which the direction of progression of the backbone changes at the two thymine residues. Intra-strand stacking interactions (including an interaction between the endocylic O atom of a ribose moiety and the adjacent purine base), hydrogen bonds and cobalt-ion interactions stabilize the double-folded structure of the single strand. Two such double-folded strands come together in the crystal to form a dimer. Inter-strand Watson–Crick hydrogen bonds form four base pairs. This portion of the decamer structure is similar to that observed in other previously reported oligonucleotide structures and has been dubbed a `bi-loop'. Both the double-folded single-strand structure, as well as the dimeric bi-loop structure, serve as starting points to construct models for triplet-repeat DNA sequences, which have been implicated in many human diseases.},
  author       = {Thirugnanasambandam, Arunachalam and Karthik, Selvam and Mandal, Pradeep K and Gautham, Namasivayam},
  issn         = {1399-0047},
  journal      = {Acta Crystallographica Section D Structural Biology},
  number       = {10},
  pages        = {2119--2126},
  publisher    = {International Union of Crystallography},
  title        = {{The novel double-folded structure of d(GCATGCATGC): A possible model for triplet-repeat sequences}},
  doi          = {10.1107/s1399004715013930},
  volume       = {71},
  year         = {2015},
}