---
_id: '12133'
abstract:
- lang: eng
  text: Social distancing is an effective way to prevent the spread of disease in
    societies, whereas infection elimination is a key element of organismal immunity.
    Here, we discuss how the study of social insects such as ants — which form a superorganism
    of unconditionally cooperative individuals and thus represent a level of organization
    that is intermediate between a classical society of individuals and an organism
    of cells — can help to determine common principles of disease defence across levels
    of organization.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Cremer S, Sixt MK. Principles of disease defence in organisms, superorganisms
    and societies. <i>Nature Reviews Immunology</i>. 2022;22(12):713-714. doi:<a href="https://doi.org/10.1038/s41577-022-00797-y">10.1038/s41577-022-00797-y</a>
  apa: Cremer, S., &#38; Sixt, M. K. (2022). Principles of disease defence in organisms,
    superorganisms and societies. <i>Nature Reviews Immunology</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41577-022-00797-y">https://doi.org/10.1038/s41577-022-00797-y</a>
  chicago: Cremer, Sylvia, and Michael K Sixt. “Principles of Disease Defence in Organisms,
    Superorganisms and Societies.” <i>Nature Reviews Immunology</i>. Springer Nature,
    2022. <a href="https://doi.org/10.1038/s41577-022-00797-y">https://doi.org/10.1038/s41577-022-00797-y</a>.
  ieee: S. Cremer and M. K. Sixt, “Principles of disease defence in organisms, superorganisms
    and societies,” <i>Nature Reviews Immunology</i>, vol. 22, no. 12. Springer Nature,
    pp. 713–714, 2022.
  ista: Cremer S, Sixt MK. 2022. Principles of disease defence in organisms, superorganisms
    and societies. Nature Reviews Immunology. 22(12), 713–714.
  mla: Cremer, Sylvia, and Michael K. Sixt. “Principles of Disease Defence in Organisms,
    Superorganisms and Societies.” <i>Nature Reviews Immunology</i>, vol. 22, no.
    12, Springer Nature, 2022, pp. 713–14, doi:<a href="https://doi.org/10.1038/s41577-022-00797-y">10.1038/s41577-022-00797-y</a>.
  short: S. Cremer, M.K. Sixt, Nature Reviews Immunology 22 (2022) 713–714.
corr_author: '1'
date_created: 2023-01-12T12:03:14Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2024-10-09T21:03:33Z
day: '01'
department:
- _id: SyCr
- _id: MiSi
doi: 10.1038/s41577-022-00797-y
external_id:
  isi:
  - '000871836300001'
  pmid:
  - '36284178'
intvolume: '        22'
isi: 1
issue: '12'
keyword:
- Energy Engineering and Power Technology
- Fuel Technology
language:
- iso: eng
month: '12'
oa_version: None
page: 713-714
pmid: 1
publication: Nature Reviews Immunology
publication_identifier:
  eissn:
  - 1474-1741
  issn:
  - 1474-1733
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Principles of disease defence in organisms, superorganisms and societies
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2022'
...
---
_id: '6824'
abstract:
- lang: eng
  text: Platelets are small anucleate cellular fragments that are released by megakaryocytes
    and safeguard vascular integrity through a process termed ‘haemostasis’. However,
    platelets have important roles beyond haemostasis as they contribute to the initiation
    and coordination of intravascular immune responses. They continuously monitor
    blood vessel integrity and tightly coordinate vascular trafficking and functions
    of multiple cell types. In this way platelets act as ‘patrolling officers of the
    vascular highway’ that help to establish effective immune responses to infections
    and cancer. Here we discuss the distinct biological features of platelets that
    allow them to shape immune responses to pathogens and tumour cells, highlighting
    the parallels between these responses.
article_processing_charge: No
article_type: original
author:
- first_name: Florian R
  full_name: Gärtner, Florian R
  id: 397A88EE-F248-11E8-B48F-1D18A9856A87
  last_name: Gärtner
  orcid: 0000-0001-6120-3723
- first_name: Steffen
  full_name: Massberg, Steffen
  last_name: Massberg
citation:
  ama: 'Gärtner FR, Massberg S. Patrolling the vascular borders: Platelets in immunity
    to infection and cancer. <i>Nature Reviews Immunology</i>. 2019;19(12):747–760.
    doi:<a href="https://doi.org/10.1038/s41577-019-0202-z">10.1038/s41577-019-0202-z</a>'
  apa: 'Gärtner, F. R., &#38; Massberg, S. (2019). Patrolling the vascular borders:
    Platelets in immunity to infection and cancer. <i>Nature Reviews Immunology</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41577-019-0202-z">https://doi.org/10.1038/s41577-019-0202-z</a>'
  chicago: 'Gärtner, Florian R, and Steffen Massberg. “Patrolling the Vascular Borders:
    Platelets in Immunity to Infection and Cancer.” <i>Nature Reviews Immunology</i>.
    Springer Nature, 2019. <a href="https://doi.org/10.1038/s41577-019-0202-z">https://doi.org/10.1038/s41577-019-0202-z</a>.'
  ieee: 'F. R. Gärtner and S. Massberg, “Patrolling the vascular borders: Platelets
    in immunity to infection and cancer,” <i>Nature Reviews Immunology</i>, vol. 19,
    no. 12. Springer Nature, pp. 747–760, 2019.'
  ista: 'Gärtner FR, Massberg S. 2019. Patrolling the vascular borders: Platelets
    in immunity to infection and cancer. Nature Reviews Immunology. 19(12), 747–760.'
  mla: 'Gärtner, Florian R., and Steffen Massberg. “Patrolling the Vascular Borders:
    Platelets in Immunity to Infection and Cancer.” <i>Nature Reviews Immunology</i>,
    vol. 19, no. 12, Springer Nature, 2019, pp. 747–760, doi:<a href="https://doi.org/10.1038/s41577-019-0202-z">10.1038/s41577-019-0202-z</a>.'
  short: F.R. Gärtner, S. Massberg, Nature Reviews Immunology 19 (2019) 747–760.
date_created: 2019-08-20T17:24:32Z
date_published: 2019-12-01T00:00:00Z
date_updated: 2025-04-14T07:43:17Z
day: '01'
department:
- _id: MiSi
doi: 10.1038/s41577-019-0202-z
ec_funded: 1
external_id:
  isi:
  - '000499090600011'
  pmid:
  - '31409920'
intvolume: '        19'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 747–760
pmid: 1
project:
- _id: 260AA4E2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '747687'
  name: Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells
publication: Nature Reviews Immunology
publication_identifier:
  eissn:
  - 1474-1741
  issn:
  - 1474-1733
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Patrolling the vascular borders: Platelets in immunity to infection and cancer'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 19
year: '2019'
...