---
_id: '2175'
abstract:
- lang: eng
  text: The cerebral cortex, the seat of our cognitive abilities, is composed of an
    intricate network of billions of excitatory projection and inhibitory interneurons.
    Postmitotic cortical neurons are generated by a diverse set of neural stem cell
    progenitors within dedicated zones and defined periods of neurogenesis during
    embryonic development. Disruptions in neurogenesis can lead to alterations in
    the neuronal cytoarchitecture, which is thought to represent a major underlying
    cause for several neurological disorders, including microcephaly, autism and epilepsy.
    Although a number of signaling pathways regulating neurogenesis have been described,
    the precise cellular and molecular mechanisms regulating the functional neural
    stem cell properties in cortical neurogenesis remain unclear. Here, we discuss
    the most up-to-date strategies to monitor the fundamental mechanistic parameters
    of neuronal progenitor proliferation, and recent advances deciphering the logic
    and dynamics of neurogenesis.
article_processing_charge: No
author:
- first_name: Maria P
  full_name: Postiglione, Maria P
  id: 2C67902A-F248-11E8-B48F-1D18A9856A87
  last_name: Postiglione
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: 'Postiglione MP, Hippenmeyer S. Monitoring neurogenesis in the cerebral cortex:
    an update. <i>Future Neurology</i>. 2014;9(3):323-340. doi:<a href="https://doi.org/10.2217/fnl.14.18">10.2217/fnl.14.18</a>'
  apa: 'Postiglione, M. P., &#38; Hippenmeyer, S. (2014). Monitoring neurogenesis
    in the cerebral cortex: an update. <i>Future Neurology</i>. Future Science Group.
    <a href="https://doi.org/10.2217/fnl.14.18">https://doi.org/10.2217/fnl.14.18</a>'
  chicago: 'Postiglione, Maria P, and Simon Hippenmeyer. “Monitoring Neurogenesis
    in the Cerebral Cortex: An Update.” <i>Future Neurology</i>. Future Science Group,
    2014. <a href="https://doi.org/10.2217/fnl.14.18">https://doi.org/10.2217/fnl.14.18</a>.'
  ieee: 'M. P. Postiglione and S. Hippenmeyer, “Monitoring neurogenesis in the cerebral
    cortex: an update,” <i>Future Neurology</i>, vol. 9, no. 3. Future Science Group,
    pp. 323–340, 2014.'
  ista: 'Postiglione MP, Hippenmeyer S. 2014. Monitoring neurogenesis in the cerebral
    cortex: an update. Future Neurology. 9(3), 323–340.'
  mla: 'Postiglione, Maria P., and Simon Hippenmeyer. “Monitoring Neurogenesis in
    the Cerebral Cortex: An Update.” <i>Future Neurology</i>, vol. 9, no. 3, Future
    Science Group, 2014, pp. 323–40, doi:<a href="https://doi.org/10.2217/fnl.14.18">10.2217/fnl.14.18</a>.'
  short: M.P. Postiglione, S. Hippenmeyer, Future Neurology 9 (2014) 323–340.
corr_author: '1'
date_created: 2018-12-11T11:56:09Z
date_published: 2014-05-01T00:00:00Z
date_updated: 2025-04-15T07:31:57Z
day: '01'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.2217/fnl.14.18
ec_funded: 1
file:
- access_level: open_access
  checksum: ba06659ecadabceec9a37dd8c4586dce
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:25Z
  date_updated: 2020-07-14T12:45:31Z
  file_id: '4812'
  file_name: IST-2016-528-v1+1_fnl.14.18.pdf
  file_size: 3848424
  relation: main_file
file_date_updated: 2020-07-14T12:45:31Z
has_accepted_license: '1'
intvolume: '         9'
issue: '3'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 323 - 340
project:
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '618444'
  name: Molecular Mechanisms of Cerebral Cortex Development
publication: Future Neurology
publication_identifier:
  eissn:
  - 1748-6971
  issn:
  - 1479-6708
publication_status: published
publisher: Future Science Group
publist_id: '4806'
pubrep_id: '528'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Monitoring neurogenesis in the cerebral cortex: an update'
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2014'
...