---
_id: '8957'
abstract:
- lang: eng
  text: Global tissue tension anisotropy has been shown to trigger stereotypical cell
    division orientation by elongating mitotic cells along the main tension axis.
    Yet, how tissue tension elongates mitotic cells despite those cells undergoing
    mitotic rounding (MR) by globally upregulating cortical actomyosin tension remains
    unclear. We addressed this question by taking advantage of ascidian embryos, consisting
    of a small number of interphasic and mitotic blastomeres and displaying an invariant
    division pattern. We found that blastomeres undergo MR by locally relaxing cortical
    tension at their apex, thereby allowing extrinsic pulling forces from neighboring
    interphasic blastomeres to polarize their shape and thus division orientation.
    Consistently, interfering with extrinsic forces by reducing the contractility
    of interphasic blastomeres or disrupting the establishment of asynchronous mitotic
    domains leads to aberrant mitotic cell division orientations. Thus, apical relaxation
    during MR constitutes a key mechanism by which tissue tension anisotropy controls
    stereotypical cell division orientation.
acknowledged_ssus:
- _id: Bio
- _id: NanoFab
acknowledgement: 'We thank members of the Heisenberg and McDougall groups for technical
  advice and discussion, Hitoyoshi Yasuo for sharing lab equipment, Lucas Leclère
  and Hitoyoshi Yasuo for their comments on a preliminary version of the manuscript,
  and Philippe Dru for the Rose plots. We are grateful to the Bioimaging and Nanofabrication
  facilities of IST Austria and the Imaging Platform (PIM) and animal facility (CRB)
  of Institut de la Mer de Villefranche (IMEV), which is supported by EMBRC-France,
  whose French state funds are managed by the ANR within the Investments of the Future
  program under reference ANR-10-INBS-0, for continuous support. This work was supported
  by a grant from the French Government funding agency Agence National de la Recherche
  (ANR “MorCell”: ANR-17-CE 13-002 8).'
article_processing_charge: No
article_type: original
author:
- first_name: Benoit G
  full_name: Godard, Benoit G
  id: 33280250-F248-11E8-B48F-1D18A9856A87
  last_name: Godard
- first_name: Rémi
  full_name: Dumollard, Rémi
  last_name: Dumollard
- first_name: Edwin
  full_name: Munro, Edwin
  last_name: Munro
- first_name: Janet
  full_name: Chenevert, Janet
  last_name: Chenevert
- first_name: Céline
  full_name: Hebras, Céline
  last_name: Hebras
- first_name: Alex
  full_name: Mcdougall, Alex
  last_name: Mcdougall
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Godard BG, Dumollard R, Munro E, et al. Apical relaxation during mitotic rounding
    promotes tension-oriented cell division. <i>Developmental Cell</i>. 2020;55(6):695-706.
    doi:<a href="https://doi.org/10.1016/j.devcel.2020.10.016">10.1016/j.devcel.2020.10.016</a>
  apa: Godard, B. G., Dumollard, R., Munro, E., Chenevert, J., Hebras, C., Mcdougall,
    A., &#38; Heisenberg, C.-P. J. (2020). Apical relaxation during mitotic rounding
    promotes tension-oriented cell division. <i>Developmental Cell</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.devcel.2020.10.016">https://doi.org/10.1016/j.devcel.2020.10.016</a>
  chicago: Godard, Benoit G, Rémi Dumollard, Edwin Munro, Janet Chenevert, Céline
    Hebras, Alex Mcdougall, and Carl-Philipp J Heisenberg. “Apical Relaxation during
    Mitotic Rounding Promotes Tension-Oriented Cell Division.” <i>Developmental Cell</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.devcel.2020.10.016">https://doi.org/10.1016/j.devcel.2020.10.016</a>.
  ieee: B. G. Godard <i>et al.</i>, “Apical relaxation during mitotic rounding promotes
    tension-oriented cell division,” <i>Developmental Cell</i>, vol. 55, no. 6. Elsevier,
    pp. 695–706, 2020.
  ista: Godard BG, Dumollard R, Munro E, Chenevert J, Hebras C, Mcdougall A, Heisenberg
    C-PJ. 2020. Apical relaxation during mitotic rounding promotes tension-oriented
    cell division. Developmental Cell. 55(6), 695–706.
  mla: Godard, Benoit G., et al. “Apical Relaxation during Mitotic Rounding Promotes
    Tension-Oriented Cell Division.” <i>Developmental Cell</i>, vol. 55, no. 6, Elsevier,
    2020, pp. 695–706, doi:<a href="https://doi.org/10.1016/j.devcel.2020.10.016">10.1016/j.devcel.2020.10.016</a>.
  short: B.G. Godard, R. Dumollard, E. Munro, J. Chenevert, C. Hebras, A. Mcdougall,
    C.-P.J. Heisenberg, Developmental Cell 55 (2020) 695–706.
corr_author: '1'
date_created: 2020-12-20T23:01:19Z
date_published: 2020-12-21T00:00:00Z
date_updated: 2025-07-10T12:01:28Z
day: '21'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2020.10.016
external_id:
  isi:
  - '000600665700008'
  pmid:
  - '33207225'
intvolume: '        55'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 695-706
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/relaxing-cell-divisions/
scopus_import: '1'
status: public
title: Apical relaxation during mitotic rounding promotes tension-oriented cell division
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2020'
...
---
_id: '1067'
abstract:
- lang: eng
  text: Embryo morphogenesis relies on highly coordinated movements of different tissues.
    However, remarkably little is known about how tissues coordinate their movements
    to shape the embryo. In zebrafish embryogenesis, coordinated tissue movements
    first become apparent during “doming,” when the blastoderm begins to spread over
    the yolk sac, a process involving coordinated epithelial surface cell layer expansion
    and mesenchymal deep cell intercalations. Here, we find that active surface cell
    expansion represents the key process coordinating tissue movements during doming.
    By using a combination of theory and experiments, we show that epithelial surface
    cells not only trigger blastoderm expansion by reducing tissue surface tension,
    but also drive blastoderm thinning by inducing tissue contraction through radial
    deep cell intercalations. Thus, coordinated tissue expansion and thinning during
    doming relies on surface cells simultaneously controlling tissue surface tension
    and radial tissue contraction.
acknowledged_ssus:
- _id: PreCl
article_processing_charge: No
author:
- first_name: Hitoshi
  full_name: Morita, Hitoshi
  id: 4C6E54C6-F248-11E8-B48F-1D18A9856A87
  last_name: Morita
- first_name: Silvia
  full_name: Grigolon, Silvia
  last_name: Grigolon
- first_name: Martin
  full_name: Bock, Martin
  last_name: Bock
- first_name: Gabriel
  full_name: Krens, Gabriel
  id: 2B819732-F248-11E8-B48F-1D18A9856A87
  last_name: Krens
  orcid: 0000-0003-4761-5996
- first_name: Guillaume
  full_name: Salbreux, Guillaume
  last_name: Salbreux
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Morita H, Grigolon S, Bock M, Krens G, Salbreux G, Heisenberg C-PJ. The physical
    basis of coordinated tissue spreading in zebrafish gastrulation. <i>Developmental
    Cell</i>. 2017;40(4):354-366. doi:<a href="https://doi.org/10.1016/j.devcel.2017.01.010">10.1016/j.devcel.2017.01.010</a>
  apa: Morita, H., Grigolon, S., Bock, M., Krens, G., Salbreux, G., &#38; Heisenberg,
    C.-P. J. (2017). The physical basis of coordinated tissue spreading in zebrafish
    gastrulation. <i>Developmental Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.devcel.2017.01.010">https://doi.org/10.1016/j.devcel.2017.01.010</a>
  chicago: Morita, Hitoshi, Silvia Grigolon, Martin Bock, Gabriel Krens, Guillaume
    Salbreux, and Carl-Philipp J Heisenberg. “The Physical Basis of Coordinated Tissue
    Spreading in Zebrafish Gastrulation.” <i>Developmental Cell</i>. Cell Press, 2017.
    <a href="https://doi.org/10.1016/j.devcel.2017.01.010">https://doi.org/10.1016/j.devcel.2017.01.010</a>.
  ieee: H. Morita, S. Grigolon, M. Bock, G. Krens, G. Salbreux, and C.-P. J. Heisenberg,
    “The physical basis of coordinated tissue spreading in zebrafish gastrulation,”
    <i>Developmental Cell</i>, vol. 40, no. 4. Cell Press, pp. 354–366, 2017.
  ista: Morita H, Grigolon S, Bock M, Krens G, Salbreux G, Heisenberg C-PJ. 2017.
    The physical basis of coordinated tissue spreading in zebrafish gastrulation.
    Developmental Cell. 40(4), 354–366.
  mla: Morita, Hitoshi, et al. “The Physical Basis of Coordinated Tissue Spreading
    in Zebrafish Gastrulation.” <i>Developmental Cell</i>, vol. 40, no. 4, Cell Press,
    2017, pp. 354–66, doi:<a href="https://doi.org/10.1016/j.devcel.2017.01.010">10.1016/j.devcel.2017.01.010</a>.
  short: H. Morita, S. Grigolon, M. Bock, G. Krens, G. Salbreux, C.-P.J. Heisenberg,
    Developmental Cell 40 (2017) 354–366.
corr_author: '1'
date_created: 2018-12-11T11:49:58Z
date_published: 2017-02-27T00:00:00Z
date_updated: 2025-07-10T11:49:55Z
day: '27'
ddc:
- '572'
- '597'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2017.01.010
ec_funded: 1
external_id:
  isi:
  - '000395368300007'
file:
- access_level: open_access
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:57Z
  date_updated: 2018-12-12T10:10:57Z
  file_id: '4849'
  file_name: IST-2017-869-v1+1_1-s2.0-S1534580717300370-main.pdf
  file_size: 6866187
  relation: main_file
file_date_updated: 2018-12-12T10:10:57Z
has_accepted_license: '1'
intvolume: '        40'
isi: 1
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 354 - 366
project:
- _id: 2524F500-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '201439'
  name: Developing High-Throughput Bioassays for Human Cancers in Zebrafish
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Cell Press
publist_id: '6320'
pubrep_id: '869'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The physical basis of coordinated tissue spreading in zebrafish gastrulation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 40
year: '2017'
...
---
_id: '729'
abstract:
- lang: eng
  text: The cellular mechanisms allowing tissues to efficiently regenerate are not
    fully understood. In this issue of Developmental Cell, Cao et al. (2017)) discover
    that during zebrafish heart regeneration, epicardial cells at the leading edge
    of regenerating tissue undergo endoreplication, possibly due to increased tissue
    tension, thereby boosting their regenerative capacity.
article_processing_charge: No
author:
- first_name: Zoltan P
  full_name: Spiro, Zoltan P
  id: 426AD026-F248-11E8-B48F-1D18A9856A87
  last_name: Spiro
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Spiro ZP, Heisenberg C-PJ. Regeneration tensed up polyploidy takes the lead.
    <i>Developmental Cell</i>. 2017;42(6):559-560. doi:<a href="https://doi.org/10.1016/j.devcel.2017.09.008">10.1016/j.devcel.2017.09.008</a>
  apa: Spiro, Z. P., &#38; Heisenberg, C.-P. J. (2017). Regeneration tensed up polyploidy
    takes the lead. <i>Developmental Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.devcel.2017.09.008">https://doi.org/10.1016/j.devcel.2017.09.008</a>
  chicago: Spiro, Zoltan P, and Carl-Philipp J Heisenberg. “Regeneration Tensed up
    Polyploidy Takes the Lead.” <i>Developmental Cell</i>. Cell Press, 2017. <a href="https://doi.org/10.1016/j.devcel.2017.09.008">https://doi.org/10.1016/j.devcel.2017.09.008</a>.
  ieee: Z. P. Spiro and C.-P. J. Heisenberg, “Regeneration tensed up polyploidy takes
    the lead,” <i>Developmental Cell</i>, vol. 42, no. 6. Cell Press, pp. 559–560,
    2017.
  ista: Spiro ZP, Heisenberg C-PJ. 2017. Regeneration tensed up polyploidy takes the
    lead. Developmental Cell. 42(6), 559–560.
  mla: Spiro, Zoltan P., and Carl-Philipp J. Heisenberg. “Regeneration Tensed up Polyploidy
    Takes the Lead.” <i>Developmental Cell</i>, vol. 42, no. 6, Cell Press, 2017,
    pp. 559–60, doi:<a href="https://doi.org/10.1016/j.devcel.2017.09.008">10.1016/j.devcel.2017.09.008</a>.
  short: Z.P. Spiro, C.-P.J. Heisenberg, Developmental Cell 42 (2017) 559–560.
corr_author: '1'
date_created: 2018-12-11T11:48:11Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2025-07-10T11:54:28Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2017.09.008
external_id:
  isi:
  - '000411582800003'
intvolume: '        42'
isi: 1
issue: '6'
language:
- iso: eng
month: '01'
oa_version: None
page: 559 - 560
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Cell Press
publist_id: '6948'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regeneration tensed up polyploidy takes the lead
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2017'
...
---
_id: '735'
abstract:
- lang: eng
  text: Cell-cell contact formation constitutes an essential step in evolution, leading
    to the differentiation of specialized cell types. However, remarkably little is
    known about whether and how the interplay between contact formation and fate specification
    affects development. Here, we identify a positive feedback loop between cell-cell
    contact duration, morphogen signaling, and mesendoderm cell-fate specification
    during zebrafish gastrulation. We show that long-lasting cell-cell contacts enhance
    the competence of prechordal plate (ppl) progenitor cells to respond to Nodal
    signaling, required for ppl cell-fate specification. We further show that Nodal
    signaling promotes ppl cell-cell contact duration, generating a positive feedback
    loop between ppl cell-cell contact duration and cell-fate specification. Finally,
    by combining mathematical modeling and experimentation, we show that this feedback
    determines whether anterior axial mesendoderm cells become ppl or, instead, turn
    into endoderm. Thus, the interdependent activities of cell-cell signaling and
    contact formation control fate diversification within the developing embryo.
article_processing_charge: No
author:
- first_name: Vanessa
  full_name: Barone, Vanessa
  id: 419EECCC-F248-11E8-B48F-1D18A9856A87
  last_name: Barone
  orcid: 0000-0003-2676-3367
- first_name: Moritz
  full_name: Lang, Moritz
  id: 29E0800A-F248-11E8-B48F-1D18A9856A87
  last_name: Lang
- first_name: Gabriel
  full_name: Krens, Gabriel
  id: 2B819732-F248-11E8-B48F-1D18A9856A87
  last_name: Krens
  orcid: 0000-0003-4761-5996
- first_name: Saurabh
  full_name: Pradhan, Saurabh
  last_name: Pradhan
- first_name: Shayan
  full_name: Shamipour, Shayan
  id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
  last_name: Shamipour
- first_name: Keisuke
  full_name: Sako, Keisuke
  id: 3BED66BE-F248-11E8-B48F-1D18A9856A87
  last_name: Sako
  orcid: 0000-0002-6453-8075
- first_name: Mateusz K
  full_name: Sikora, Mateusz K
  id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
  last_name: Sikora
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Barone V, Lang M, Krens G, et al. An effective feedback loop between cell-cell
    contact duration and morphogen signaling determines cell fate. <i>Developmental
    Cell</i>. 2017;43(2):198-211. doi:<a href="https://doi.org/10.1016/j.devcel.2017.09.014">10.1016/j.devcel.2017.09.014</a>
  apa: Barone, V., Lang, M., Krens, G., Pradhan, S., Shamipour, S., Sako, K., … Heisenberg,
    C.-P. J. (2017). An effective feedback loop between cell-cell contact duration
    and morphogen signaling determines cell fate. <i>Developmental Cell</i>. Cell
    Press. <a href="https://doi.org/10.1016/j.devcel.2017.09.014">https://doi.org/10.1016/j.devcel.2017.09.014</a>
  chicago: Barone, Vanessa, Moritz Lang, Gabriel Krens, Saurabh Pradhan, Shayan Shamipour,
    Keisuke Sako, Mateusz K Sikora, Calin C Guet, and Carl-Philipp J Heisenberg. “An
    Effective Feedback Loop between Cell-Cell Contact Duration and Morphogen Signaling
    Determines Cell Fate.” <i>Developmental Cell</i>. Cell Press, 2017. <a href="https://doi.org/10.1016/j.devcel.2017.09.014">https://doi.org/10.1016/j.devcel.2017.09.014</a>.
  ieee: V. Barone <i>et al.</i>, “An effective feedback loop between cell-cell contact
    duration and morphogen signaling determines cell fate,” <i>Developmental Cell</i>,
    vol. 43, no. 2. Cell Press, pp. 198–211, 2017.
  ista: Barone V, Lang M, Krens G, Pradhan S, Shamipour S, Sako K, Sikora MK, Guet
    CC, Heisenberg C-PJ. 2017. An effective feedback loop between cell-cell contact
    duration and morphogen signaling determines cell fate. Developmental Cell. 43(2),
    198–211.
  mla: Barone, Vanessa, et al. “An Effective Feedback Loop between Cell-Cell Contact
    Duration and Morphogen Signaling Determines Cell Fate.” <i>Developmental Cell</i>,
    vol. 43, no. 2, Cell Press, 2017, pp. 198–211, doi:<a href="https://doi.org/10.1016/j.devcel.2017.09.014">10.1016/j.devcel.2017.09.014</a>.
  short: V. Barone, M. Lang, G. Krens, S. Pradhan, S. Shamipour, K. Sako, M.K. Sikora,
    C.C. Guet, C.-P.J. Heisenberg, Developmental Cell 43 (2017) 198–211.
corr_author: '1'
date_created: 2018-12-11T11:48:13Z
date_published: 2017-10-23T00:00:00Z
date_updated: 2026-08-13T22:30:20Z
day: '23'
department:
- _id: CaHe
- _id: CaGu
- _id: GaTk
doi: 10.1016/j.devcel.2017.09.014
ec_funded: 1
external_id:
  isi:
  - '000413443700011'
intvolume: '        43'
isi: 1
issue: '2'
language:
- iso: eng
month: '10'
oa_version: None
page: 198 - 211
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 252DD2A6-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I2058
  name: 'Cell segregation in gastrulation: the role of cell fate specification'
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Cell Press
publist_id: '6934'
quality_controlled: '1'
related_material:
  record:
  - id: '961'
    relation: dissertation_contains
    status: public
  - id: '8350'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: An effective feedback loop between cell-cell contact duration and morphogen
  signaling determines cell fate
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2017'
...
---
OA_place: publisher
OA_type: free access
_id: '932'
abstract:
- lang: eng
  text: Epithelial sheets are crucial components of all metazoan animals, enclosing
    organs and protecting the animal from its environment. Epithelial homeostasis
    poses unique challenges, as addition of new cells and loss of old cells must be
    achieved without disrupting the fluid-tight barrier and apicobasal polarity of
    the epithelium. Several studies have identified cell biological mechanisms underlying
    extrusion of cells from epithelia, but far less is known of the converse mechanism
    by which new cells are added. Here, we combine molecular, pharmacological, and
    laser-dissection experiments with theoretical modeling to characterize forces
    driving emergence of an apical surface as single nascent cells are added to a
    vertebrate epithelium in vivo. We find that this process involves the interplay
    between cell-autonomous actin-generated pushing forces in the emerging cell and
    mechanical properties of neighboring cells. Our findings define the forces driving
    this cell behavior, contributing to a more comprehensive understanding of epithelial
    homeostasis.
acknowledgement: We thank J. Bear, B. Goldstein, A. Ewald, and D. Soroldoni for critical
  reading. This work was funded by an EMBO Long Term Fellowship to J.S., a Research
  Fellowship from Trinity College, Cambridge and a Bettencourt-Schueller Foundation
  Young Researcher Prize to E.H., a Cancer Institute NSW Early Career Researcher fellowship
  (13/ECF/1–25) and a Cancer Australia/Cure Cancer Australia Foundation project grant
  (1070498) to M.B., and grants from the NHLBI (HL117164) and NIGMS (GM074104) to
  J.B.W. J.B.W. was an early career scientist of the Howard Hughes Medical Institute.
  This work was initiated at the New Quantitative Approaches to Morphogenesis Workshop
  at UCSB, which is funded in part by the National Science Foundation (PHY11-25915)
  and the NIGMS (GM067110-05).
article_processing_charge: No
article_type: original
author:
- first_name: Jakub
  full_name: Sedzinski, Jakub
  last_name: Sedzinski
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Fan
  full_name: Tu, Fan
  last_name: Tu
- first_name: Maté
  full_name: Biro, Maté
  last_name: Biro
- first_name: John
  full_name: Wallingford, John
  last_name: Wallingford
citation:
  ama: Sedzinski J, Hannezo EB, Tu F, Biro M, Wallingford J. Emergence of an Apical
    Epithelial Cell Surface In Vivo. <i>Developmental Cell</i>. 2016;36(1):24-35.
    doi:<a href="https://doi.org/10.1016/j.devcel.2015.12.013">10.1016/j.devcel.2015.12.013</a>
  apa: Sedzinski, J., Hannezo, E. B., Tu, F., Biro, M., &#38; Wallingford, J. (2016).
    Emergence of an Apical Epithelial Cell Surface In Vivo. <i>Developmental Cell</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.devcel.2015.12.013">https://doi.org/10.1016/j.devcel.2015.12.013</a>
  chicago: Sedzinski, Jakub, Edouard B Hannezo, Fan Tu, Maté Biro, and John Wallingford.
    “Emergence of an Apical Epithelial Cell Surface In Vivo.” <i>Developmental Cell</i>.
    Elsevier, 2016. <a href="https://doi.org/10.1016/j.devcel.2015.12.013">https://doi.org/10.1016/j.devcel.2015.12.013</a>.
  ieee: J. Sedzinski, E. B. Hannezo, F. Tu, M. Biro, and J. Wallingford, “Emergence
    of an Apical Epithelial Cell Surface In Vivo,” <i>Developmental Cell</i>, vol.
    36, no. 1. Elsevier, pp. 24–35, 2016.
  ista: Sedzinski J, Hannezo EB, Tu F, Biro M, Wallingford J. 2016. Emergence of an
    Apical Epithelial Cell Surface In Vivo. Developmental Cell. 36(1), 24–35.
  mla: Sedzinski, Jakub, et al. “Emergence of an Apical Epithelial Cell Surface In
    Vivo.” <i>Developmental Cell</i>, vol. 36, no. 1, Elsevier, 2016, pp. 24–35, doi:<a
    href="https://doi.org/10.1016/j.devcel.2015.12.013">10.1016/j.devcel.2015.12.013</a>.
  short: J. Sedzinski, E.B. Hannezo, F. Tu, M. Biro, J. Wallingford, Developmental
    Cell 36 (2016) 24–35.
date_created: 2018-12-11T11:49:16Z
date_published: 2016-01-12T00:00:00Z
date_updated: 2026-05-20T09:14:43Z
day: '12'
doi: 10.1016/j.devcel.2015.12.013
extern: '1'
external_id:
  pmid:
  - '26766441'
intvolume: '        36'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2015.12.013
month: '01'
oa: 1
oa_version: Published Version
page: 24 - 35
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
publist_id: '6510'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Emergence of an Apical Epithelial Cell Surface In Vivo
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 36
year: '2016'
...
---
_id: '11968'
abstract:
- lang: eng
  text: 'Membrane phospholipids typically contain fatty acids (FAs) of 16 and 18 carbon
    atoms. This particular chain length is evolutionarily highly conserved and presumably
    provides maximum stability and dynamic properties to biological membranes in response
    to nutritional or environmental cues. Here, we show that the relative proportion
    of C16 versus C18 FAs is regulated by the activity of acetyl-CoA carboxylase (Acc1),
    the first and rate-limiting enzyme of FA de novo synthesis. Acc1 activity is attenuated
    by AMPK/Snf1-dependent phosphorylation, which is required to maintain an appropriate
    acyl-chain length distribution. Moreover, we find that the transcriptional repressor
    Opi1 preferentially binds to C16 over C18 phosphatidic acid (PA) species: thus,
    C16-chain containing PA sequesters Opi1 more effectively to the ER, enabling AMPK/Snf1
    control of PA acyl-chain length to determine the degree of derepression of Opi1
    target genes. These findings reveal an unexpected regulatory link between the
    major energy-sensing kinase, membrane lipid composition, and transcription.'
article_processing_charge: No
article_type: original
author:
- first_name: Harald F.
  full_name: Hofbauer, Harald F.
  last_name: Hofbauer
- first_name: Florian H.
  full_name: Schopf, Florian H.
  last_name: Schopf
- first_name: Hannes
  full_name: Schleifer, Hannes
  last_name: Schleifer
- first_name: Oskar L.
  full_name: Knittelfelder, Oskar L.
  last_name: Knittelfelder
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
- first_name: Gerald N.
  full_name: Rechberger, Gerald N.
  last_name: Rechberger
- first_name: Heimo
  full_name: Wolinski, Heimo
  last_name: Wolinski
- first_name: Maria L.
  full_name: Gaspar, Maria L.
  last_name: Gaspar
- first_name: C. Oliver
  full_name: Kappe, C. Oliver
  last_name: Kappe
- first_name: Johannes
  full_name: Stadlmann, Johannes
  last_name: Stadlmann
- first_name: Karl
  full_name: Mechtler, Karl
  last_name: Mechtler
- first_name: Alexandra
  full_name: Zenz, Alexandra
  last_name: Zenz
- first_name: Karl
  full_name: Lohner, Karl
  last_name: Lohner
- first_name: Oksana
  full_name: Tehlivets, Oksana
  last_name: Tehlivets
- first_name: Susan A.
  full_name: Henry, Susan A.
  last_name: Henry
- first_name: Sepp D.
  full_name: Kohlwein, Sepp D.
  last_name: Kohlwein
citation:
  ama: Hofbauer HF, Schopf FH, Schleifer H, et al. Regulation of gene expression through
    a transcriptional repressor that senses acyl-chain length in membrane phospholipids.
    <i>Developmental Cell</i>. 2014;29(6):P729-739. doi:<a href="https://doi.org/10.1016/j.devcel.2014.04.025">10.1016/j.devcel.2014.04.025</a>
  apa: Hofbauer, H. F., Schopf, F. H., Schleifer, H., Knittelfelder, O. L., Pieber,
    B., Rechberger, G. N., … Kohlwein, S. D. (2014). Regulation of gene expression
    through a transcriptional repressor that senses acyl-chain length in membrane
    phospholipids. <i>Developmental Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2014.04.025">https://doi.org/10.1016/j.devcel.2014.04.025</a>
  chicago: Hofbauer, Harald F., Florian H. Schopf, Hannes Schleifer, Oskar L. Knittelfelder,
    Bartholomäus Pieber, Gerald N. Rechberger, Heimo Wolinski, et al. “Regulation
    of Gene Expression through a Transcriptional Repressor That Senses Acyl-Chain
    Length in Membrane Phospholipids.” <i>Developmental Cell</i>. Elsevier, 2014.
    <a href="https://doi.org/10.1016/j.devcel.2014.04.025">https://doi.org/10.1016/j.devcel.2014.04.025</a>.
  ieee: H. F. Hofbauer <i>et al.</i>, “Regulation of gene expression through a transcriptional
    repressor that senses acyl-chain length in membrane phospholipids,” <i>Developmental
    Cell</i>, vol. 29, no. 6. Elsevier, pp. P729-739, 2014.
  ista: Hofbauer HF, Schopf FH, Schleifer H, Knittelfelder OL, Pieber B, Rechberger
    GN, Wolinski H, Gaspar ML, Kappe CO, Stadlmann J, Mechtler K, Zenz A, Lohner K,
    Tehlivets O, Henry SA, Kohlwein SD. 2014. Regulation of gene expression through
    a transcriptional repressor that senses acyl-chain length in membrane phospholipids.
    Developmental Cell. 29(6), P729-739.
  mla: Hofbauer, Harald F., et al. “Regulation of Gene Expression through a Transcriptional
    Repressor That Senses Acyl-Chain Length in Membrane Phospholipids.” <i>Developmental
    Cell</i>, vol. 29, no. 6, Elsevier, 2014, pp. P729-739, doi:<a href="https://doi.org/10.1016/j.devcel.2014.04.025">10.1016/j.devcel.2014.04.025</a>.
  short: H.F. Hofbauer, F.H. Schopf, H. Schleifer, O.L. Knittelfelder, B. Pieber,
    G.N. Rechberger, H. Wolinski, M.L. Gaspar, C.O. Kappe, J. Stadlmann, K. Mechtler,
    A. Zenz, K. Lohner, O. Tehlivets, S.A. Henry, S.D. Kohlwein, Developmental Cell
    29 (2014) P729-739.
date_created: 2022-08-25T08:42:42Z
date_published: 2014-06-23T00:00:00Z
date_updated: 2023-02-21T10:09:45Z
day: '23'
doi: 10.1016/j.devcel.2014.04.025
extern: '1'
external_id:
  pmid:
  - '24960695'
intvolume: '        29'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2014.04.025
month: '06'
oa: 1
oa_version: Published Version
page: P729-739
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of gene expression through a transcriptional repressor that senses
  acyl-chain length in membrane phospholipids
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2014'
...
---
_id: '9520'
abstract:
- lang: eng
  text: Plants undergo alternation of generation in which reproductive cells develop
    in the plant body ("sporophytic generation") and then differentiate into a multicellular
    gamete-forming "gametophytic generation." Different populations of helper cells
    assist in this transgenerational journey, with somatic tissues supporting early
    development and single nurse cells supporting gametogenesis. New data reveal a
    two-way relationship between early reproductive cells and their helpers involving
    complex epigenetic and signaling networks determining cell number and fate. Later,
    the egg cell plays a central role in specifying accessory cells, whereas in both
    gametophytes, companion cells contribute non-cell-autonomously to the epigenetic
    landscape of the gamete genomes.
article_processing_charge: No
article_type: review
author:
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
- first_name: Hugh
  full_name: Dickinson, Hugh
  last_name: Dickinson
citation:
  ama: 'Feng X, Zilberman D, Dickinson H. A conversation across generations: Soma-germ
    cell crosstalk in plants. <i>Developmental Cell</i>. 2013;24(3):215-225. doi:<a
    href="https://doi.org/10.1016/j.devcel.2013.01.014">10.1016/j.devcel.2013.01.014</a>'
  apa: 'Feng, X., Zilberman, D., &#38; Dickinson, H. (2013). A conversation across
    generations: Soma-germ cell crosstalk in plants. <i>Developmental Cell</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.devcel.2013.01.014">https://doi.org/10.1016/j.devcel.2013.01.014</a>'
  chicago: 'Feng, Xiaoqi, Daniel Zilberman, and Hugh Dickinson. “A Conversation across
    Generations: Soma-Germ Cell Crosstalk in Plants.” <i>Developmental Cell</i>. Elsevier,
    2013. <a href="https://doi.org/10.1016/j.devcel.2013.01.014">https://doi.org/10.1016/j.devcel.2013.01.014</a>.'
  ieee: 'X. Feng, D. Zilberman, and H. Dickinson, “A conversation across generations:
    Soma-germ cell crosstalk in plants,” <i>Developmental Cell</i>, vol. 24, no. 3.
    Elsevier, pp. 215–225, 2013.'
  ista: 'Feng X, Zilberman D, Dickinson H. 2013. A conversation across generations:
    Soma-germ cell crosstalk in plants. Developmental Cell. 24(3), 215–225.'
  mla: 'Feng, Xiaoqi, et al. “A Conversation across Generations: Soma-Germ Cell Crosstalk
    in Plants.” <i>Developmental Cell</i>, vol. 24, no. 3, Elsevier, 2013, pp. 215–25,
    doi:<a href="https://doi.org/10.1016/j.devcel.2013.01.014">10.1016/j.devcel.2013.01.014</a>.'
  short: X. Feng, D. Zilberman, H. Dickinson, Developmental Cell 24 (2013) 215–225.
date_created: 2021-06-08T06:14:50Z
date_published: 2013-02-11T00:00:00Z
date_updated: 2023-05-08T11:00:59Z
day: '11'
department:
- _id: DaZi
- _id: XiFe
doi: 10.1016/j.devcel.2013.01.014
extern: '1'
external_id:
  pmid:
  - '23410937'
intvolume: '        24'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2013.01.014
month: '02'
oa: 1
oa_version: Published Version
page: 215-225
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A conversation across generations: Soma-germ cell crosstalk in plants'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2013'
...
---
_id: '11093'
abstract:
- lang: eng
  text: Nuclear pore complexes (NPCs) are built from ∼30 different proteins called
    nucleoporins or Nups. Previous studies have shown that several Nups exhibit cell-type-specific
    expression and that mutations in NPC components result in tissue-specific diseases.
    Here we show that a specific change in NPC composition is required for both myogenic
    and neuronal differentiation. The transmembrane nucleoporin Nup210 is absent in
    proliferating myoblasts and embryonic stem cells (ESCs) but becomes expressed
    and incorporated into NPCs during cell differentiation. Preventing Nup210 production
    by RNAi blocks myogenesis and the differentiation of ESCs into neuroprogenitors.
    We found that the addition of Nup210 to NPCs does not affect nuclear transport
    but is required for the induction of genes that are essential for cell differentiation.
    Our results identify a single change in NPC composition as an essential step in
    cell differentiation and establish a role for Nup210 in gene expression regulation
    and cell fate determination.
article_processing_charge: No
article_type: original
author:
- first_name: Maximiliano A.
  full_name: D'Angelo, Maximiliano A.
  last_name: D'Angelo
- first_name: J. Sebastian
  full_name: Gomez-Cavazos, J. Sebastian
  last_name: Gomez-Cavazos
- first_name: Arianna
  full_name: Mei, Arianna
  last_name: Mei
- first_name: Daniel H.
  full_name: Lackner, Daniel H.
  last_name: Lackner
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: D’Angelo MA, Gomez-Cavazos JS, Mei A, Lackner DH, Hetzer M. A change in nuclear
    pore complex composition regulates cell differentiation. <i>Developmental Cell</i>.
    2012;22(2):446-458. doi:<a href="https://doi.org/10.1016/j.devcel.2011.11.021">10.1016/j.devcel.2011.11.021</a>
  apa: D’Angelo, M. A., Gomez-Cavazos, J. S., Mei, A., Lackner, D. H., &#38; Hetzer,
    M. (2012). A change in nuclear pore complex composition regulates cell differentiation.
    <i>Developmental Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2011.11.021">https://doi.org/10.1016/j.devcel.2011.11.021</a>
  chicago: D’Angelo, Maximiliano A., J. Sebastian Gomez-Cavazos, Arianna Mei, Daniel H.
    Lackner, and Martin Hetzer. “A Change in Nuclear Pore Complex Composition Regulates
    Cell Differentiation.” <i>Developmental Cell</i>. Elsevier, 2012. <a href="https://doi.org/10.1016/j.devcel.2011.11.021">https://doi.org/10.1016/j.devcel.2011.11.021</a>.
  ieee: M. A. D’Angelo, J. S. Gomez-Cavazos, A. Mei, D. H. Lackner, and M. Hetzer,
    “A change in nuclear pore complex composition regulates cell differentiation,”
    <i>Developmental Cell</i>, vol. 22, no. 2. Elsevier, pp. 446–458, 2012.
  ista: D’Angelo MA, Gomez-Cavazos JS, Mei A, Lackner DH, Hetzer M. 2012. A change
    in nuclear pore complex composition regulates cell differentiation. Developmental
    Cell. 22(2), 446–458.
  mla: D’Angelo, Maximiliano A., et al. “A Change in Nuclear Pore Complex Composition
    Regulates Cell Differentiation.” <i>Developmental Cell</i>, vol. 22, no. 2, Elsevier,
    2012, pp. 446–58, doi:<a href="https://doi.org/10.1016/j.devcel.2011.11.021">10.1016/j.devcel.2011.11.021</a>.
  short: M.A. D’Angelo, J.S. Gomez-Cavazos, A. Mei, D.H. Lackner, M. Hetzer, Developmental
    Cell 22 (2012) 446–458.
date_created: 2022-04-07T07:52:10Z
date_published: 2012-01-19T00:00:00Z
date_updated: 2024-10-14T11:26:00Z
day: '19'
doi: 10.1016/j.devcel.2011.11.021
extern: '1'
external_id:
  pmid:
  - '22264802'
intvolume: '        22'
issue: '2'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2011.11.021
month: '01'
oa: 1
oa_version: Published Version
page: 446-458
pmid: 1
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: A change in nuclear pore complex composition regulates cell differentiation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2012'
...
---
_id: '9522'
abstract:
- lang: eng
  text: Little is known about chromatin remodeling events immediately after fertilization.
    A recent report by Autran et al. (2011) in Cell now shows that chromatin regulatory
    pathways that silence transposable elements are responsible for global delayed
    activation of gene expression in the early Arabidopsis embryo.
article_processing_charge: No
author:
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Zilberman D. <i>Balancing Parental Contributions in Plant Embryonic Gene Activation</i>.
    Vol 20. Elsevier; 2011:735-736. doi:<a href="https://doi.org/10.1016/j.devcel.2011.05.018">10.1016/j.devcel.2011.05.018</a>
  apa: Zilberman, D. (2011). <i>Balancing parental contributions in plant embryonic
    gene activation</i>. <i>Developmental Cell</i> (Vol. 20, pp. 735–736). Elsevier.
    <a href="https://doi.org/10.1016/j.devcel.2011.05.018">https://doi.org/10.1016/j.devcel.2011.05.018</a>
  chicago: Zilberman, Daniel. <i>Balancing Parental Contributions in Plant Embryonic
    Gene Activation</i>. <i>Developmental Cell</i>. Vol. 20. Elsevier, 2011. <a href="https://doi.org/10.1016/j.devcel.2011.05.018">https://doi.org/10.1016/j.devcel.2011.05.018</a>.
  ieee: D. Zilberman, <i>Balancing parental contributions in plant embryonic gene
    activation</i>, vol. 20, no. 6. Elsevier, 2011, pp. 735–736.
  ista: Zilberman D. 2011. Balancing parental contributions in plant embryonic gene
    activation, Elsevier,p.
  mla: Zilberman, Daniel. “Balancing Parental Contributions in Plant Embryonic Gene
    Activation.” <i>Developmental Cell</i>, vol. 20, no. 6, Elsevier, 2011, pp. 735–36,
    doi:<a href="https://doi.org/10.1016/j.devcel.2011.05.018">10.1016/j.devcel.2011.05.018</a>.
  short: D. Zilberman, Balancing Parental Contributions in Plant Embryonic Gene Activation,
    Elsevier, 2011.
date_created: 2021-06-08T06:23:39Z
date_published: 2011-06-14T00:00:00Z
date_updated: 2021-12-14T08:34:37Z
day: '14'
department:
- _id: DaZi
doi: 10.1016/j.devcel.2011.05.018
extern: '1'
external_id:
  pmid:
  - '21664571'
intvolume: '        20'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2011.05.018
month: '06'
oa: 1
oa_version: Published Version
page: 735-736
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Balancing parental contributions in plant embryonic gene activation
type: other_academic_publication
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 20
year: '2011'
...
---
_id: '11103'
abstract:
- lang: eng
  text: Over the last decade, the nuclear envelope (NE) has emerged as a key component
    in the organization and function of the nuclear genome. As many as 100 different
    proteins are thought to specifically localize to this double membrane that separates
    the cytoplasm and the nucleoplasm of eukaryotic cells. Selective portals through
    the NE are formed at sites where the inner and outer nuclear membranes are fused,
    and the coincident assembly of ∼30 proteins into nuclear pore complexes occurs.
    These nuclear pore complexes are essential for the control of nucleocytoplasmic
    exchange. Many of the NE and nuclear pore proteins are thought to play crucial
    roles in gene regulation and thus are increasingly linked to human diseases.
article_processing_charge: No
article_type: review
author:
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Susan R.
  full_name: Wente, Susan R.
  last_name: Wente
citation:
  ama: 'Hetzer M, Wente SR. Border control at the nucleus: Biogenesis and organization
    of the nuclear membrane and pore complexes. <i>Developmental Cell</i>. 2009;17(5):606-616.
    doi:<a href="https://doi.org/10.1016/j.devcel.2009.10.007">10.1016/j.devcel.2009.10.007</a>'
  apa: 'Hetzer, M., &#38; Wente, S. R. (2009). Border control at the nucleus: Biogenesis
    and organization of the nuclear membrane and pore complexes. <i>Developmental
    Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2009.10.007">https://doi.org/10.1016/j.devcel.2009.10.007</a>'
  chicago: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
    and Organization of the Nuclear Membrane and Pore Complexes.” <i>Developmental
    Cell</i>. Elsevier, 2009. <a href="https://doi.org/10.1016/j.devcel.2009.10.007">https://doi.org/10.1016/j.devcel.2009.10.007</a>.'
  ieee: 'M. Hetzer and S. R. Wente, “Border control at the nucleus: Biogenesis and
    organization of the nuclear membrane and pore complexes,” <i>Developmental Cell</i>,
    vol. 17, no. 5. Elsevier, pp. 606–616, 2009.'
  ista: 'Hetzer M, Wente SR. 2009. Border control at the nucleus: Biogenesis and organization
    of the nuclear membrane and pore complexes. Developmental Cell. 17(5), 606–616.'
  mla: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
    and Organization of the Nuclear Membrane and Pore Complexes.” <i>Developmental
    Cell</i>, vol. 17, no. 5, Elsevier, 2009, pp. 606–16, doi:<a href="https://doi.org/10.1016/j.devcel.2009.10.007">10.1016/j.devcel.2009.10.007</a>.'
  short: M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.
date_created: 2022-04-07T07:53:45Z
date_published: 2009-11-17T00:00:00Z
date_updated: 2024-10-14T11:28:25Z
day: '17'
doi: 10.1016/j.devcel.2009.10.007
extern: '1'
external_id:
  pmid:
  - '19922866'
intvolume: '        17'
issue: '5'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2009.10.007
month: '11'
oa: 1
oa_version: Published Version
page: 606-616
pmid: 1
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Border control at the nucleus: Biogenesis and organization of the nuclear
  membrane and pore complexes'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2009'
...
---
_id: '4168'
abstract:
- lang: eng
  text: Recent studies show that signaling through integrin receptors is required
    for normal cell movements during Xenopus gastrulation. Integrins function in this
    process by modulating the activity of cadherin adhesion molecules within tissues
    undergoing convergence and extension movements.
article_processing_charge: No
article_type: original
author:
- first_name: Juan
  full_name: Montero, Juan
  last_name: Montero
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Montero J, Heisenberg C-PJ. Adhesive crosstalk in gastrulation. <i>Developmental
    Cell</i>. 2003;5(2):190-191. doi:<a href="https://doi.org/10.1016/S1534-5807(03)00235-1">10.1016/S1534-5807(03)00235-1</a>
  apa: Montero, J., &#38; Heisenberg, C.-P. J. (2003). Adhesive crosstalk in gastrulation.
    <i>Developmental Cell</i>. Cell Press. <a href="https://doi.org/10.1016/S1534-5807(03)00235-1">https://doi.org/10.1016/S1534-5807(03)00235-1</a>
  chicago: Montero, Juan, and Carl-Philipp J Heisenberg. “Adhesive Crosstalk in Gastrulation.”
    <i>Developmental Cell</i>. Cell Press, 2003. <a href="https://doi.org/10.1016/S1534-5807(03)00235-1">https://doi.org/10.1016/S1534-5807(03)00235-1</a>.
  ieee: J. Montero and C.-P. J. Heisenberg, “Adhesive crosstalk in gastrulation,”
    <i>Developmental Cell</i>, vol. 5, no. 2. Cell Press, pp. 190–191, 2003.
  ista: Montero J, Heisenberg C-PJ. 2003. Adhesive crosstalk in gastrulation. Developmental
    Cell. 5(2), 190–191.
  mla: Montero, Juan, and Carl-Philipp J. Heisenberg. “Adhesive Crosstalk in Gastrulation.”
    <i>Developmental Cell</i>, vol. 5, no. 2, Cell Press, 2003, pp. 190–91, doi:<a
    href="https://doi.org/10.1016/S1534-5807(03)00235-1">10.1016/S1534-5807(03)00235-1</a>.
  short: J. Montero, C.-P.J. Heisenberg, Developmental Cell 5 (2003) 190–191.
date_created: 2018-12-11T12:07:21Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2024-02-27T09:54:53Z
day: '01'
doi: 10.1016/S1534-5807(03)00235-1
extern: '1'
external_id:
  pmid:
  - '12919669 '
intvolume: '         5'
issue: '2'
language:
- iso: eng
month: '08'
oa_version: None
page: 190 - 191
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Cell Press
publist_id: '1949'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adhesive crosstalk in gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 5
year: '2003'
...