---
_id: '3798'
abstract:
- lang: eng
  text: Glutamate is the main excitatory transmitter in the mammalian CNS, mediating
    fast synaptic transmission primarily by activation of AMPA-type glutamate receptor
    channels. Both synaptic structure and a cell-specific molecular switch in the
    AMPA receptor subunit expression are involved in the regulation of the synaptic
    signaling time course.
acknowledgement: I thank Drs. J.R.P. Geiger,  K.  Haverkampf,  and  B.  Taskin  for  helpful
  discussions.  This review is based on a lecture  given in Lisbon in March 1998 on
  the occasion of the first award of the Medinfar European Prize in Physiology. My
  studies are supported by the Deutsche Forschungsgemeinschaft, the German Israeli
  Foundation, and the Human Frontiers Science Program Organization. I regret that
  many relevant papers could not be cited due to editorial restric-tions on the maximum
  number of references.
article_processing_charge: No
article_type: original
author:
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Jonas PM. The time course of signaling at central glutamatergic synapses. <i>Physiology</i>.
    2000;15(2):83-89. doi:<a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">10.1152/physiologyonline.2000.15.2.83</a>
  apa: Jonas, P. M. (2000). The time course of signaling at central glutamatergic
    synapses. <i>Physiology</i>. American Physiological Society. <a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">https://doi.org/10.1152/physiologyonline.2000.15.2.83</a>
  chicago: Jonas, Peter M. “The Time Course of Signaling at Central Glutamatergic
    Synapses.” <i>Physiology</i>. American Physiological Society, 2000. <a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">https://doi.org/10.1152/physiologyonline.2000.15.2.83</a>.
  ieee: P. M. Jonas, “The time course of signaling at central glutamatergic synapses,”
    <i>Physiology</i>, vol. 15, no. 2. American Physiological Society, pp. 83–89,
    2000.
  ista: Jonas PM. 2000. The time course of signaling at central glutamatergic synapses.
    Physiology. 15(2), 83–89.
  mla: Jonas, Peter M. “The Time Course of Signaling at Central Glutamatergic Synapses.”
    <i>Physiology</i>, vol. 15, no. 2, American Physiological Society, 2000, pp. 83–89,
    doi:<a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">10.1152/physiologyonline.2000.15.2.83</a>.
  short: P.M. Jonas, Physiology 15 (2000) 83–89.
date_created: 2018-12-11T12:05:14Z
date_published: 2000-04-01T00:00:00Z
date_updated: 2023-05-02T11:57:50Z
day: '01'
doi: 10.1152/physiologyonline.2000.15.2.83
extern: '1'
external_id:
  pmid:
  - '11390884'
intvolume: '        15'
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 83 - 89
pmid: 1
publication: Physiology
publication_identifier:
  issn:
  - 1548-9213
publication_status: published
publisher: American Physiological Society
publist_id: '2412'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The time course of signaling at central glutamatergic synapses
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2000'
...