@article{700,
  abstract     = {Microtubules provide the mechanical force required for chromosome separation during mitosis. However, little is known about the dynamic (high-frequency) mechanical properties of microtubules. Here, we theoretically propose to control the vibrations of a doubly clamped microtubule by tip electrodes and to detect its motion via the optomechanical coupling between the vibrational modes of the microtubule and an optical cavity. In the presence of a red-detuned strong pump laser, this coupling leads to optomechanical-induced transparency of an optical probe field, which can be detected with state-of-the art technology. The center frequency and line width of the transparency peak give the resonance frequency and damping rate of the microtubule, respectively, while the height of the peak reveals information about the microtubule-cavity field coupling. Our method opens the new possibilities to gain information about the physical properties of microtubules, which will enhance our capability to design physical cancer treatment protocols as alternatives to chemotherapeutic drugs.},
  author       = {Barzanjeh, Shabir and Salari, Vahid and Tuszynski, Jack and Cifra, Michal and Simon, Christoph},
  issn         = {2470-0045},
  journal      = {Physical Review E},
  number       = {1},
  publisher    = {American Physical Society},
  title        = {{Optomechanical proposal for monitoring microtubule mechanical vibrations}},
  doi          = {10.1103/PhysRevE.96.012404},
  volume       = {96},
  year         = {2017},
}

@article{959,
  abstract     = {In this work it is shown that scale-free tails in metabolic flux distributions inferred in stationary models are an artifact due to reactions involved in thermodynamically unfeasible cycles, unbounded by physical constraints and in principle able to perform work without expenditure of free energy. After implementing thermodynamic constraints by removing such loops, metabolic flux distributions scale meaningfully with the physical limiting factors, acquiring in turn a richer multimodal structure potentially leading to symmetry breaking while optimizing for objective functions.},
  author       = {De Martino, Daniele},
  issn         = {2470-0045},
  journal      = {Physical Review E},
  number       = {6},
  pages        = {062419},
  publisher    = {American Physical Society},
  title        = {{Scales and multimodal flux distributions in stationary metabolic network models via thermodynamics}},
  doi          = {10.1103/PhysRevE.95.062419},
  volume       = {95},
  year         = {2017},
}

@article{931,
  abstract     = {In many adult tissues, stem cells and differentiated cells are not homogeneously distributed: stem cells are arranged in periodic &quot;niches,&quot; and differentiated cells are constantly produced and migrate out of these niches. In this article, we provide a general theoretical framework to study mixtures of dividing and actively migrating particles, which we apply to biological tissues. We show in particular that the interplay between the stresses arising from active cell migration and stem cell division give rise to robust stem cell patterns. The instability of the tissue leads to spatial patterns which are either steady or oscillating in time. The wavelength of the instability has an order of magnitude consistent with the biological observations. We also discuss the implications of these results for future in vitro and in vivo experiments.},
  author       = {Hannezo, Edouard B and Coucke, Alice and Joanny, Jean},
  issn         = {2470-0053},
  journal      = {Physical Review E },
  number       = {2},
  publisher    = {American Institute of Physics},
  title        = {{Interplay of migratory and division forces as a generic mechanism for stem cell patterns}},
  doi          = {10.1103/PhysRevE.93.022405},
  volume       = {93},
  year         = {2016},
}

