[{"_id":"22684","doi_confirm":"1","oa_version":"Published Version","department":[{"_id":"GradSch"},{"_id":"ScWa"}],"project":[{"name":"Tribocharge: a multi-scale approach to an enduring problem in physics","grant_number":"949120","call_identifier":"H2020","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa"}],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.15479/AT-ISTA-22684","citation":{"chicago":"Pertl, Felix. “Experimental Probing of Nanoscale Charge Features and Surface Morphology Changes during Tribocharging.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22684\">https://doi.org/10.15479/AT-ISTA-22684</a>.","short":"F. Pertl, Experimental Probing of Nanoscale Charge Features and Surface Morphology Changes during Tribocharging, Institute of Science and Technology Austria, 2026.","ieee":"F. Pertl, “Experimental probing of nanoscale charge features and surface morphology changes during tribocharging,” Institute of Science and Technology Austria, 2026.","mla":"Pertl, Felix. <i>Experimental Probing of Nanoscale Charge Features and Surface Morphology Changes during Tribocharging</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22684\">10.15479/AT-ISTA-22684</a>.","ista":"Pertl F. 2026. Experimental probing of nanoscale charge features and surface morphology changes during tribocharging. Institute of Science and Technology Austria.","apa":"Pertl, F. (2026). <i>Experimental probing of nanoscale charge features and surface morphology changes during tribocharging</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22684\">https://doi.org/10.15479/AT-ISTA-22684</a>","ama":"Pertl F. Experimental probing of nanoscale charge features and surface morphology changes during tribocharging. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22684\">10.15479/AT-ISTA-22684</a>"},"author":[{"full_name":"Pertl, Felix","id":"6313aec0-15b2-11ec-abd3-ed67d16139af","last_name":"Pertl","orcid":"0000-0003-0463-5794","first_name":"Felix"}],"date_updated":"2026-08-27T11:42:44Z","title":"Experimental probing of nanoscale charge features and surface morphology changes during tribocharging","related_material":{"record":[{"relation":"part_of_dissertation","id":"20481","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"12109"},{"status":"public","id":"19278","relation":"part_of_dissertation"},{"id":"17373","relation":"part_of_dissertation","status":"public"}]},"acknowledgement":"This project has received financing from the European Research Council grant agreement\r\nno. 949120 under the European Union’s Horizon 2020 research and innovation programme.\r\nThis research was supported by the Scientific Service Units of The Institute of Science\r\nand Technology Austria (ISTA) through resources provided by the Miba Machine Shop, the\r\nNanofabrication Facility, the Lab Support Facility, the Scientific Computing Facility and the\r\nElectron Microscopy Facility. We thank Florian Stumpf from Park Systems for useful discussions\r\nand support with scanning probe microscopy. We thank Joaquin Garcia-Suarez and Guillaume\r\nAnciaux for the suggestion to look into the roughness power spectral density. We thank\r\nIrina-Malina Strugaru for help with testing the device for Young’s modulus measurements.\r\n","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-083-1"]},"file_date_updated":"2026-08-12T13:04:21Z","day":"12","OA_place":"publisher","degree_awarded":"PhD","acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"EM-Fac"}],"month":"08","ddc":["530"],"status":"public","corr_author":"1","alternative_title":["ISTA Thesis"],"date_created":"2026-08-12T09:44:40Z","has_accepted_license":"1","abstract":[{"text":"Contact electrification (CE) is a simple yet elusive phenomenon that occurs when two materials come into contact and separate, leaving behind net electrical charge. Despite its ubiquity, the microscopic origin of CE remains unclear. In this thesis, we investigate CE from three complementary perspectives: developing a quantitative method to measure charge at the nanoscale, exploring the dynamic behavior of charge on insulating surfaces, and uncovering the role of mechanical history in forming a triboelectric series.\r\n\r\nIn the first part, we establish a rigorous framework for converting qualitative Kelvin probe force microscopy (KPFM) voltage maps into quantitative charge density distributions. Using finite element method (FEM) simulations, we determine the point-spread function of the KPFM tip–sample geometry and demonstrate that the true surface charge can be reconstructed by numerical deconvolution. This procedure enables the recovery of both the magnitude and sign of charge density with high fidelity, resolving nanoscale features that are otherwise obscured. Applying the method to contact-charged SiO$_2$ surfaces, we show that existing analytical approximations, such as parallel plate or spherical models, can miscalculate charge magnitude by orders of magnitude. Our hybrid FEM/KPFM approach therefore provides a fast and general method to convert qualitative KPFM signals into quantitative charge data, enabling nanoscale charge mapping under realistic experimental conditions.\r\n\r\nIn the second part, we study the temporal stability of CE-induced charges and identify the key material factors that determine whether KPFM can capture meaningful charge patterns. Through time-resolved experiments combining a custom-built transfer system with both microscopic and macroscopic measurements, we demonstrate that only the best insulators, such as SiO$_2$, preserve CE charge long enough for stationary imaging. For less conductive polymers, such as PDMS, charge decays within the duration of a single KPFM scan due to bulk conduction. Using a simple capacitor-based model, we reproduce the observed decay dynamics and confirm that the transferred charge decays characteristic to the sample's bulk conductivity. Further, we always observe homogeneous charge transfer.\r\n\r\nIn the third part, we address the question: can we form a triboelectric series with identical materials? Using controlled repetitive contact experiments, we show that nominally identical materials can progressively order themselves into a triboelectric series, where surfaces with more contact history charge negatively relative to fresher ones. By constructing a minimal model based on this ``contact bias'', we replicate the evolution from random to ordered charging observed in experiments. Supporting surface analyses, including atomic force microscopy, reveal that repeated contact induces nanoscale morphological changes, suggesting a mechanism tightly coupled to mechanical strain. These results highlight the crucial role of surface history and nanoscale mechanics in dictating charge transfer, motivating further exploration of mechanisms such as mechanochemical bond cleavage and flexoelectric polarization.","lang":"eng"}],"publisher":"Institute of Science and Technology Austria","supervisor":[{"full_name":"Waitukaitis, Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","last_name":"Waitukaitis","orcid":"0000-0002-2299-3176"}],"language":[{"iso":"eng"}],"article_processing_charge":"No","year":"2026","publication_status":"published","file":[{"date_created":"2026-08-12T13:04:21Z","relation":"source_file","creator":"fpertl","file_name":"2026_Pertl_Felix_Thesis.zip","checksum":"0a4f5a941c40b921447e72291d72bc6f","file_size":31192621,"access_level":"closed","content_type":"application/x-zip-compressed","file_id":"22690","date_updated":"2026-08-12T13:04:21Z"},{"access_level":"open_access","content_type":"application/pdf","file_size":27882509,"checksum":"ae60dcdb363222138886b2857643d4e3","creator":"fpertl","file_name":"2026_Pertl_Felix_Thesis.pdf","date_created":"2026-08-12T13:04:21Z","relation":"main_file","date_updated":"2026-08-12T13:04:21Z","file_id":"22691"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2026-08-12T00:00:00Z","page":"107","type":"dissertation","ec_funded":1,"oa":1},{"degree_awarded":"PhD","status":"public","month":"08","corr_author":"1","ddc":["572"],"date_created":"2026-08-21T09:29:34Z","has_accepted_license":"1","alternative_title":["ISTA Thesis"],"publisher":"Institute of Science and Technology Austria","language":[{"iso":"eng"}],"supervisor":[{"full_name":"Bernecky, Carrie A","id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","last_name":"Bernecky","orcid":"0000-0003-0893-7036","first_name":"Carrie A"}],"publication_status":"published","article_processing_charge":"No","year":"2026","file":[{"file_id":"22763","embargo":"2027-08-26","date_updated":"2026-08-26T08:46:02Z","embargo_to":"open_access","checksum":"cd80d2076a5155ab6a12ec0b05adbee5","creator":"cchlebak","file_name":"2026_Michalik_David_Thesis.pdf","date_created":"2026-08-26T08:46:02Z","relation":"main_file","access_level":"closed","content_type":"application/pdf","file_size":13624837},{"file_id":"22764","date_updated":"2026-08-26T08:46:35Z","file_name":"2026_Michalik_David_Thesis.docx","checksum":"16ae6cd206ba0eb04ce8a7198042f24f","creator":"cchlebak","relation":"source_file","date_created":"2026-08-26T08:46:35Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","file_size":20499216}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2026-08-21T00:00:00Z","page":"182","type":"dissertation","_id":"22745","oa_version":"Published Version","doi_confirm":"1","department":[{"_id":"CaBe"},{"_id":"GradSch"}],"project":[{"_id":"059C9F64-7A3F-11EA-A408-12923DDC885E","grant_number":"F8003","name":"RNAdeco: decorating RNA for a purpose"}],"tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png"},"citation":{"ista":"Michalik D. 2026. Mechanistic insights into MDA5 selectivity and regulation. Institute of Science and Technology Austria.","apa":"Michalik, D. (2026). <i>Mechanistic insights into MDA5 selectivity and regulation</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22745\">https://doi.org/10.15479/AT-ISTA-22745</a>","ama":"Michalik D. Mechanistic insights into MDA5 selectivity and regulation. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22745\">10.15479/AT-ISTA-22745</a>","ieee":"D. Michalik, “Mechanistic insights into MDA5 selectivity and regulation,” Institute of Science and Technology Austria, 2026.","mla":"Michalik, David. <i>Mechanistic Insights into MDA5 Selectivity and Regulation</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22745\">10.15479/AT-ISTA-22745</a>.","short":"D. Michalik, Mechanistic Insights into MDA5 Selectivity and Regulation, Institute of Science and Technology Austria, 2026.","chicago":"Michalik, David. “Mechanistic Insights into MDA5 Selectivity and Regulation.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22745\">https://doi.org/10.15479/AT-ISTA-22745</a>."},"doi":"10.15479/AT-ISTA-22745","author":[{"last_name":"Michalik","first_name":"David","id":"B9577E20-AA38-11E9-AC9A-0930E6697425","full_name":"Michalik, David"}],"title":"Mechanistic insights into MDA5 selectivity and regulation","date_updated":"2026-08-28T08:34:46Z","day":"21","publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"This research was supported by the Scientific Service Units of Institute of Science and\r\nTechnology Austria through resources provided by the Lab Support Facility and Electron\r\nMicroscopy Facility at ISTA. Monoclonal Antibody Facility at Max Perutz laboratories are\r\nacknowledged for raising anti-pSer1022 MDA5 antibody. Proteomics core facility CEITEC MUNI\r\nBrno, namely David Pospíšil, are acknowledged for their help with measuring MS data as well\r\nas help with interpreting them and the introduction into MS data analysis. CIISB, Instruct-CZ\r\nCentre of Instruct-ERIC EU consortium, funded by MEYS CR infrastructure project LM2023042,\r\nis gratefully acknowledged for the financial support of the measurements at the CEITEC\r\nProteomics Core Facility. Computational resources were provided by the e-INFRA CZ project\r\n(ID:90254), supported by MEYS CR.\r\nThis work was supported by the Austrian Science Fund (FWF) grant F8003-B RNA-DECO:\r\nDecorating RNA for a purpose (10.55776/F80).","file_date_updated":"2026-08-26T08:46:35Z","OA_place":"publisher","license":"https://creativecommons.org/licenses/by-sa/4.0/"},{"researchdata_availability":"upon request","title":"Calibrating the teacher synapse: Mechanisms and functional significance of presynaptic inhibition at hippocampal mossy fiber synapses","date_updated":"2026-08-31T11:11:55Z","author":[{"id":"7E3060D0-A92C-11E9-A326-26C8E5697425","full_name":"Lin, Peipeng","first_name":"Peipeng","last_name":"Lin"}],"OA_place":"publisher","day":"25","acknowledgement":"This project was supported by the following funding agencies: ERC under the European\r\nUnion's Horizon 2020 research and innovation program (ERC Advanced Grants No 692692\r\n“GIANTSYN” and 101199096 “CA3-SYNGRAM” to P.J.), the Fonds zur Förderung der\r\nwissenschaftlichen Forschung (P 36232-B, stand-alone grant, PAT 4178023, principal\r\ninvestigator project, and 10.55776/CoE 16 “GABA neurons” to P.J.), and the European Union’s\r\nHorizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant\r\nagreement (No 101034413, to K.L.).","file_date_updated":"2026-08-26T10:09:53Z","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-088-6"]},"_id":"22735","oa_version":"Published Version","doi_confirm":"1","project":[{"grant_number":"692692","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"_id":"e62b56fe-ab3c-11f0-94c7-d181dd352b3b","name":"Synaptic mechanisms of engram storage and retrieval in CA3 hippocampal microcircuits","grant_number":"101199096"},{"name":"Mechanisms of GABA release in hippocampal circuits","grant_number":"P36232","_id":"bd88be38-d553-11ed-ba76-81d5a70a6ef5"},{"_id":"8d9195e9-16d5-11f0-9cad-d075be887a1e","name":"Synaptic networks of human brain","grant_number":"PAT 4178023"},{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"doi":"10.15479/AT-ISTA-22735","tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"citation":{"short":"P. Lin, Calibrating the Teacher Synapse: Mechanisms and Functional Significance of Presynaptic Inhibition at Hippocampal Mossy Fiber Synapses, Institute of Science and Technology Austria, 2026.","chicago":"Lin, Peipeng. “Calibrating the Teacher Synapse: Mechanisms and Functional Significance of Presynaptic Inhibition at Hippocampal Mossy Fiber Synapses.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22735\">https://doi.org/10.15479/AT-ISTA-22735</a>.","ama":"Lin P. Calibrating the teacher synapse: Mechanisms and functional significance of presynaptic inhibition at hippocampal mossy fiber synapses. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22735\">10.15479/AT-ISTA-22735</a>","ista":"Lin P. 2026. Calibrating the teacher synapse: Mechanisms and functional significance of presynaptic inhibition at hippocampal mossy fiber synapses. Institute of Science and Technology Austria.","apa":"Lin, P. (2026). <i>Calibrating the teacher synapse: Mechanisms and functional significance of presynaptic inhibition at hippocampal mossy fiber synapses</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22735\">https://doi.org/10.15479/AT-ISTA-22735</a>","ieee":"P. Lin, “Calibrating the teacher synapse: Mechanisms and functional significance of presynaptic inhibition at hippocampal mossy fiber synapses,” Institute of Science and Technology Austria, 2026.","mla":"Lin, Peipeng. <i>Calibrating the Teacher Synapse: Mechanisms and Functional Significance of Presynaptic Inhibition at Hippocampal Mossy Fiber Synapses</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22735\">10.15479/AT-ISTA-22735</a>."},"department":[{"_id":"GradSch"},{"_id":"PeJo"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2026-08-25T00:00:00Z","publication_status":"published","article_processing_charge":"No","year":"2026","file":[{"relation":"main_file","date_created":"2026-08-26T10:09:48Z","creator":"plin","file_name":"2026_Lin_Peipeng_Thesis.pdf","checksum":"13cc7ead72aad90a134f310b531c73cd","file_size":6376229,"content_type":"application/pdf","access_level":"closed","file_id":"22765","embargo":"2027-09-01","embargo_to":"open_access","date_updated":"2026-08-26T10:09:48Z"},{"file_id":"22766","date_updated":"2026-08-26T10:09:53Z","creator":"plin","checksum":"8c9c1445a7df284377be1a8c9dadd7c5","file_name":"2026_Lin_Peipeng_Thesis.docx","relation":"source_file","date_created":"2026-08-26T10:09:53Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","file_size":17681883}],"type":"dissertation","ec_funded":1,"page":"88","das_tickbox":"0","corr_author":"1","status":"public","month":"08","ddc":["571","573"],"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"PreCl"},{"_id":"Bio"}],"degree_awarded":"PhD","language":[{"iso":"eng"}],"supervisor":[{"last_name":"Jonas","orcid":"0000-0001-5001-4804","first_name":"Peter M","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2026-08-18T15:23:41Z","has_accepted_license":"1","alternative_title":["ISTA Thesis"],"publisher":"Institute of Science and Technology Austria","supplementarymaterial":"yes"},{"oa_version":"Published Version","_id":"18979","department":[{"_id":"GradSch"},{"_id":"HeEd"}],"citation":{"mla":"Draganov, Ondrej. <i>Structures and Computations in Topological Data Analysis</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/at:ista:18979\">10.15479/at:ista:18979</a>.","ieee":"O. Draganov, “Structures and computations in topological data analysis,” Institute of Science and Technology Austria, 2025.","ista":"Draganov O. 2025. Structures and computations in topological data analysis. Institute of Science and Technology Austria.","apa":"Draganov, O. (2025). <i>Structures and computations in topological data analysis</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:18979\">https://doi.org/10.15479/at:ista:18979</a>","ama":"Draganov O. Structures and computations in topological data analysis. 2025. doi:<a href=\"https://doi.org/10.15479/at:ista:18979\">10.15479/at:ista:18979</a>","chicago":"Draganov, Ondrej. “Structures and Computations in Topological Data Analysis.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/at:ista:18979\">https://doi.org/10.15479/at:ista:18979</a>.","short":"O. Draganov, Structures and Computations in Topological Data Analysis, Institute of Science and Technology Austria, 2025."},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.15479/at:ista:18979","project":[{"call_identifier":"FWF","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35"},{"call_identifier":"FWF","_id":"268116B8-B435-11E9-9278-68D0E5697425","name":"Mathematics, Computer Science","grant_number":"Z00342"}],"author":[{"id":"2B23F01E-F248-11E8-B48F-1D18A9856A87","full_name":"Draganov, Ondrej","first_name":"Ondrej","orcid":"0000-0003-0464-3823","last_name":"Draganov"}],"title":"Structures and computations in topological data analysis","date_updated":"2026-04-07T11:47:30Z","day":"03","file_date_updated":"2025-02-04T16:22:07Z","publication_identifier":{"issn":["2663-337X"]},"related_material":{"record":[{"id":"15091","relation":"part_of_dissertation","status":"public"},{"relation":"part_of_dissertation","id":"18981","status":"public"}]},"acknowledgement":"The research presented in this thesis was funded with the Wittgenstein Prize,\r\nAustrian Science Fund (FWF), grant no. Z 342-N31, and from the DFG Collaborative Research\r\nCenter TRR 109, ‘Discretization in Geometry and Dynamics’, Austrian Science Fund (FWF),\r\ngrant no. I 02979-N35.\r\n","OA_place":"publisher","degree_awarded":"PhD","status":"public","month":"02","corr_author":"1","ddc":["514","004"],"publisher":"Institute of Science and Technology Austria","date_created":"2025-01-31T17:04:40Z","has_accepted_license":"1","abstract":[{"text":"Topological Data Analysis (TDA) is a discipline utilizing the mathematical field of topology to study data, most prominently collections of point sets. This thesis summarizes three projects related to computations in TDA.\r\n\r\nThe first one establishes a variant of TDA for chromatic point sets, where each point is given a color. For example, we are given positions of cells within a tumor microenvironment, and color the cancerous cells red, and the immune cells blue.\r\n\r\nThe aim is then to give a quantitative description of how the two or more sets of points spatially interact. Building on image, kernel and cokernel variants of persistent homology, we suggest six-packs of persistent diagrams as such a descriptor.\r\n\r\nWe describe a construction of a chromatic alpha complex, which enables  efficient computation of several variants of the six-packs. We give topological descriptions of natural subcomplexes of the chromatic alpha complex, and show that the radii of the simplices form a discrete Morse function. Finally, we provide an implementation of the presented chromatic TDA pipeline.\r\n\r\nThe second part aims to translate a powerful tool of sheaf theory to elementary terms using labeled matrices. The goal is to enable their use in computational settings. We show that derived categories of sheaves over finite posets have, up to isomorphism, unique objects---minimal injective resolutions---and give a concrete algorithm to compute them. We further describe simple algorithms to compute derived pushforwards and pullbacks for monotonic maps, and their proper variants for inclusions, and demonstrate their tractability by providing an implementation. Finally, we suggest a discrete definition of microsupport and show desirable properties inspired by discrete Morse theory.\r\n\r\nIn the last part, we present a collection of observations about collapses. We give a characterization of collapsibility in terms of unitriangular submatrices of the boundary matrix, a cotree-tree decomposition, and the optimal solution to a variant of the Procrustes problem. We establish relation between dual collapses and relative Morse theory and pose several open questions. Finally, focusing on complexes embedded in the three-dimensional Euclidean space, we describe a relation between the collapsibility and the triviality of a polygonal knot.","lang":"eng"}],"alternative_title":["ISTA Thesis"],"supervisor":[{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","full_name":"Edelsbrunner, Herbert","first_name":"Herbert","orcid":"0000-0002-9823-6833","last_name":"Edelsbrunner"}],"language":[{"iso":"eng"}],"file":[{"file_size":11899491,"content_type":"application/zip","access_level":"closed","relation":"source_file","date_created":"2025-01-31T16:58:30Z","creator":"odragano","file_name":"Thesis.zip","checksum":"af6567e5d35e5eb330b8925ae37f1998","date_updated":"2025-01-31T16:58:30Z","file_id":"18983"},{"date_updated":"2025-02-04T16:22:07Z","file_id":"19000","content_type":"application/pdf","access_level":"open_access","file_size":8857514,"file_name":"Thesis.pdf","checksum":"c3fef68e35b9dc2020b2ca6006da6343","creator":"odragano","relation":"main_file","date_created":"2025-02-04T16:22:07Z"}],"publication_status":"published","article_processing_charge":"No","year":"2025","keyword":["topological data analysis","chromatic point set","alpha complex","persistent homology","six pack","sheaf","microlocal discrete Morse","injective resolution","collapse","knot","discrete Morse theory"],"date_published":"2025-02-03T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"140","oa":1,"type":"dissertation"},{"page":"86","type":"dissertation","ec_funded":1,"oa":1,"publication_status":"published","article_processing_charge":"No","year":"2025","file":[{"date_updated":"2025-02-18T14:25:59Z","file_id":"19061","file_size":7779825,"content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2025-02-18T14:25:59Z","creator":"mmaslov","file_name":"thesis_Maslov.pdf","checksum":"5822a4dd31724c512b37c658af1787ab"},{"date_updated":"2025-02-18T14:25:59Z","file_id":"19062","file_size":14453726,"access_level":"open_access","content_type":"application/zip","date_created":"2025-02-18T14:25:59Z","relation":"source_file","checksum":"89bdce4774406d26ceca88a8bbcd6a9a","creator":"mmaslov","file_name":"thesis_Maslov_source.zip"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_published":"2025-02-18T00:00:00Z","abstract":[{"text":"Rotations are found in physics problems at all scales: from spatial motion of celestial bodies, to transitions between quantum states of atoms and molecules. Mathematically, they represent a fundamental class of transformations and symmetries. Unlike spatial displacements, rotational transformations in three-dimensional space  are non-commutative: the result of applying a sequence of rotations depends on the order of these operations. This feature makes the emergent physics that involves rotations rather intricate, but instrumental for studies of highly-interconnected many-body systems. In the presence of an environment, rotational properties of an object change, due to the interaction with particles of the environment. Owing to the complexity of this interaction, it can be engineered to exhibit certain properties of interest. In this Thesis, we examine several scenarios of how the rotational behavior of an impurity can be modified by interactions with its environment.","lang":"eng"}],"date_created":"2025-02-18T01:41:27Z","has_accepted_license":"1","alternative_title":["ISTA Thesis"],"publisher":"Institute of Science and Technology Austria","language":[{"iso":"eng"}],"supervisor":[{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","first_name":"Mikhail","orcid":"0000-0002-6990-7802","last_name":"Lemeshko"}],"degree_awarded":"PhD","corr_author":"1","ddc":["539","535","541"],"month":"02","status":"public","acknowledged_ssus":[{"_id":"CampIT"},{"_id":"E-Lib"},{"_id":"SSU"}],"day":"18","file_date_updated":"2025-02-18T14:25:59Z","acknowledgement":"I am grateful to the European Research Council (ERC) [10.3030/801770] and Austrian\r\nScience Fund (FWF) [10.55776/F1004] for funding my research and to the Physical\r\nReview journals for publishing it. I also want to thank the VCQ (previously CoQuS) and\r\nIQOQI for organizing wonderful networking events for the physics community in Vienna\r\nand Innsbruck, respectively. Moreover, I thank Austrian Science Fund (FWF) for the\r\ncontinuous support for quantum research.","publication_identifier":{"issn":["2663-337X"]},"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"10845"},{"relation":"part_of_dissertation","id":"7933","status":"public"},{"status":"public","id":"18087","relation":"part_of_dissertation"}]},"OA_place":"publisher","author":[{"last_name":"Maslov","orcid":"0000-0003-4074-2570","first_name":"Mikhail","full_name":"Maslov, Mikhail","id":"2E65BB0E-F248-11E8-B48F-1D18A9856A87"}],"title":"Emergent physics of rotating quantum impurities in many-body environments","date_updated":"2026-04-16T12:20:38Z","department":[{"_id":"GradSch"},{"_id":"MiLe"}],"project":[{"name":"Angulon: physics and applications of a new quasiparticle","grant_number":"801770","call_identifier":"H2020","_id":"2688CF98-B435-11E9-9278-68D0E5697425"},{"_id":"7c040762-9f16-11ee-852c-dd79eeee4ab3","grant_number":"F100403","name":"Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions"}],"doi":"10.15479/at:ista:19048","tmp":{"short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png"},"citation":{"short":"M. Maslov, Emergent Physics of Rotating Quantum Impurities in Many-Body Environments, Institute of Science and Technology Austria, 2025.","chicago":"Maslov, Mikhail. “Emergent Physics of Rotating Quantum Impurities in Many-Body Environments.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/at:ista:19048\">https://doi.org/10.15479/at:ista:19048</a>.","ista":"Maslov M. 2025. Emergent physics of rotating quantum impurities in many-body environments. Institute of Science and Technology Austria.","apa":"Maslov, M. (2025). <i>Emergent physics of rotating quantum impurities in many-body environments</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:19048\">https://doi.org/10.15479/at:ista:19048</a>","ama":"Maslov M. Emergent physics of rotating quantum impurities in many-body environments. 2025. doi:<a href=\"https://doi.org/10.15479/at:ista:19048\">10.15479/at:ista:19048</a>","ieee":"M. Maslov, “Emergent physics of rotating quantum impurities in many-body environments,” Institute of Science and Technology Austria, 2025.","mla":"Maslov, Mikhail. <i>Emergent Physics of Rotating Quantum Impurities in Many-Body Environments</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/at:ista:19048\">10.15479/at:ista:19048</a>."},"_id":"19048","oa_version":"Published Version"},{"day":"14","publication_identifier":{"issn":["2663-337X"]},"related_material":{"record":[{"relation":"part_of_dissertation","id":"12802","status":"public"},{"status":"public","id":"9429","relation":"part_of_dissertation"}]},"file_date_updated":"2026-03-27T13:15:08Z","acknowledgement":"The work presented in this doctoral thesis was performed at the Institute of Science\r\nand Technology (ISTA) and financially supported by a European Research Council\r\n(ERC) Consolidator Grant (PR1028ERC02), by SFARI (PR1028SIM02) and by the\r\nAustrian Science Fund (FWF) to Gaia Novarino (PE1028W1232). I am very thankful\r\nto the Doctoral Program “Molecular Drug Targets” (MolTag) for offering me financial\r\nsupport to perform essential experiments during my PhD studies and to participate in\r\ninternational conferences and courses.","OA_place":"publisher","author":[{"first_name":"Lena A","last_name":"Schwarz","full_name":"Schwarz, Lena A","id":"29A8453C-F248-11E8-B48F-1D18A9856A87"}],"title":"Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution","date_updated":"2026-04-14T09:07:14Z","department":[{"_id":"GradSch"},{"_id":"GaNo"}],"project":[{"_id":"9B91375C-BA93-11EA-9121-9846C619BF3A","name":"Critical windows and reversibility of ASD associated with mutations in chromatin remodelers","grant_number":"707964"},{"_id":"34ba8964-11ca-11ed-8bc3-e15864e7e9a6","grant_number":"101044865","name":"Toward an understanding of the brain interstitial system and the extracellular proteome in health and autism spectrum disorders"},{"grant_number":"W1232","name":"Molecular Drug Targets","_id":"2548AE96-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"citation":{"chicago":"Schwarz, Lena A. “Mapping Developmental Dynamics of Autism Spectrum Disorder Mouse Models at Single-Cell Resolution.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-19557\">https://doi.org/10.15479/AT-ISTA-19557</a>.","short":"L.A. Schwarz, Mapping Developmental Dynamics of Autism Spectrum Disorder Mouse Models at Single-Cell Resolution, Institute of Science and Technology Austria, 2025.","mla":"Schwarz, Lena A. <i>Mapping Developmental Dynamics of Autism Spectrum Disorder Mouse Models at Single-Cell Resolution</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19557\">10.15479/AT-ISTA-19557</a>.","ieee":"L. A. Schwarz, “Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution,” Institute of Science and Technology Austria, 2025.","ama":"Schwarz LA. Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19557\">10.15479/AT-ISTA-19557</a>","apa":"Schwarz, L. A. (2025). <i>Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-19557\">https://doi.org/10.15479/AT-ISTA-19557</a>","ista":"Schwarz LA. 2025. Mapping developmental dynamics of autism spectrum disorder mouse models at single-cell resolution. Institute of Science and Technology Austria."},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.15479/AT-ISTA-19557","_id":"19557","oa_version":"Published Version","page":"124","type":"dissertation","publication_status":"published","year":"2025","article_processing_charge":"No","file":[{"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","file_size":21783427,"file_name":"Schwarz_Thesis_2025_FINAL.docx","creator":"lschwarz","checksum":"50290a8604edb0a720387f01e9d59fe4","relation":"source_file","date_created":"2025-04-15T08:43:36Z","date_updated":"2025-04-15T08:43:36Z","file_id":"19561"},{"file_name":"Schwarz_Thesis_2025_FINALpdfa.pdf","creator":"lschwarz","checksum":"ed028488180ac4901e018ef1c330cf01","date_created":"2025-04-15T08:43:42Z","relation":"main_file","access_level":"closed","content_type":"application/pdf","file_size":11432175,"file_id":"19562","embargo":"2026-10-15","date_updated":"2026-03-27T13:15:08Z","embargo_to":"open_access"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_published":"2025-04-14T00:00:00Z","has_accepted_license":"1","date_created":"2025-04-14T06:59:06Z","alternative_title":["ISTA Thesis"],"publisher":"Institute of Science and Technology Austria","supervisor":[{"id":"3E57A680-F248-11E8-B48F-1D18A9856A87","full_name":"Novarino, Gaia","first_name":"Gaia","orcid":"0000-0002-7673-7178","last_name":"Novarino"}],"language":[{"iso":"eng"}],"degree_awarded":"PhD","month":"04","corr_author":"1","status":"public","ddc":["570"],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"ScienComp"}]},{"publisher":"Institute of Science and Technology Austria","alternative_title":["ISTA Thesis"],"abstract":[{"lang":"eng","text":"This thesis consists of three chapters, each corresponding to one publication. While each of these projects tackles a topic in a different area of research, they all share a common thread in the type of topological structure they handle - a partition of space into volumes separated by interfaces that meet in non-manifold junctions.\r\n\r\nIn Chapter 2, we study clusters of soap bubbles from a simulation perspective. In particular, we develop a surface-only algorithm that couples large scale motion and shape deformation of soap bubble clusters with the small scale evolution of the thin film's thickness, which is responsible for visual phenomena like surface vortices, Newton's interference patterns, capillary waves, and deformation-dependent rupturing of films in a foam. We model film thickness as a reduced degree of freedom in the Navier-Stokes equations and from them derive three sets of equations governing normal and tangential motion of the soap film surface, as well as the evolution of the thin film thickness. We discretize these equations on a non-manifold triangle mesh, extending and adapting operators to handle complex topology. We also present an incompressible fluid solver for 2.5D films and an advection algorithm for convecting fields across non-manifold surface junctions. Our simulations enhance bubble solvers with additional effects caused by convection, rippling, draining, and evaporation of the thin film.\r\n\r\nIn Chapter 3, we introduce a multi-material non-manifold mesh-based surface tracking algorithm that converts mesh defects, such as overlaps, self-intersections, and inversions into topological changes. Our algorithm generalizes prior work on manifold surface tracking with topological changes: it preserves surface features like mesh-based methods, and it robustly handles topological changes like level set methods. Our method also offers improved efficiency and robustness over the state of the art. We demonstrate the effectiveness of the approach on a range of examples, including complex soap film simulations, such as those presented in Chapter 2, but with an order of magnitude more interacting bubbles than what we could achieve before, and Boolean unions of non-manifold meshes consisting of millions of triangles.\r\n\r\nLastly, in Chapter 4, we utilize developments in the theory of random geometric complexes facilitated by observations from Discrete Morse theory. We survey the methods and results obtained with this new approach, and discuss some of its shortcomings. We use simulations to illustrate the results and to form conjectures, getting numerical estimates for combinatorial, topological, and geometric properties of weighted and unweighted Delaunay mosaics, their dual Voronoi tessellations, and the Alpha and Wrap complexes contained in the mosaics."}],"date_created":"2025-04-29T09:39:34Z","has_accepted_license":"1","supervisor":[{"orcid":"0000-0001-6646-5546","last_name":"Wojtan","first_name":"Christopher J","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","full_name":"Wojtan, Christopher J"}],"language":[{"iso":"eng"}],"degree_awarded":"PhD","acknowledged_ssus":[{"_id":"ScienComp"}],"status":"public","ddc":["519","006"],"month":"04","corr_author":"1","page":"106","oa":1,"ec_funded":1,"type":"dissertation","file":[{"file_id":"19633","date_updated":"2025-04-30T14:02:25Z","date_created":"2025-04-30T14:02:25Z","relation":"source_file","checksum":"f00b519c27529daa0c3b2d4102b4fa7b","file_name":"Thesis_source_Heiss_Synak.zip","creator":"cchlebak","file_size":60670543,"access_level":"closed","content_type":"application/x-zip-compressed"},{"file_id":"19634","date_updated":"2025-04-30T15:49:16Z","date_created":"2025-04-30T14:02:42Z","relation":"main_file","creator":"cchlebak","checksum":"6e40a2fd3b1b881af1385670854a682e","file_name":"Thesis_PDFA_Heiss_Synak.pdf","file_size":21319043,"access_level":"open_access","content_type":"application/pdf"}],"year":"2025","article_processing_charge":"No","publication_status":"published","date_published":"2025-04-29T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","department":[{"_id":"ChWo"},{"_id":"GradSch"}],"doi":"10.15479/AT-ISTA-19630","citation":{"mla":"Synak, Peter. <i>Methods for Fluid Simulation, Surface Tracking, and Statistics of Non-Manifold Structures</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19630\">10.15479/AT-ISTA-19630</a>.","ieee":"P. Synak, “Methods for fluid simulation, surface tracking, and statistics of non-manifold structures,” Institute of Science and Technology Austria, 2025.","ista":"Synak P. 2025. Methods for fluid simulation, surface tracking, and statistics of non-manifold structures. Institute of Science and Technology Austria.","apa":"Synak, P. (2025). <i>Methods for fluid simulation, surface tracking, and statistics of non-manifold structures</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-19630\">https://doi.org/10.15479/AT-ISTA-19630</a>","ama":"Synak P. Methods for fluid simulation, surface tracking, and statistics of non-manifold structures. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19630\">10.15479/AT-ISTA-19630</a>","chicago":"Synak, Peter. “Methods for Fluid Simulation, Surface Tracking, and Statistics of Non-Manifold Structures.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-19630\">https://doi.org/10.15479/AT-ISTA-19630</a>.","short":"P. Synak, Methods for Fluid Simulation, Surface Tracking, and Statistics of Non-Manifold Structures, Institute of Science and Technology Austria, 2025."},"project":[{"_id":"2533E772-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"638176","name":"Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large Scales"},{"_id":"34bc2376-11ca-11ed-8bc3-9a3b3961a088","name":"Computational Discovery of Numerical Algorithms for Animation and Simulation of Natural Phenomena","grant_number":"101045083"},{"grant_number":"788183","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"grant_number":"638176","name":"Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large Scales","_id":"2533E772-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35","call_identifier":"FWF","_id":"2561EBF4-B435-11E9-9278-68D0E5697425"}],"oa_version":"Published Version","_id":"19630","related_material":{"record":[{"id":"8135","relation":"part_of_dissertation","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"17219"},{"status":"public","id":"8384","relation":"part_of_dissertation"}]},"publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"The project in Chapter 2 has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme under grant agreement No. 638176. The project in Chapter 3 was funded in part by the European Union (ERC-2021-COG 101045083 CoDiNA). The project in Chapter 4 has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreements No 78818 Alpha and No 638176). It was also partially supported by the DFG Collaborative Research Center TRR 109, 'Discretization in Geometry and Dynamics', through grant no. I02979-N35 of the Austrian Science Fund (FWF). Thank you for providing funds to support my work.","file_date_updated":"2025-04-30T15:49:16Z","day":"29","OA_place":"publisher","author":[{"id":"331776E2-F248-11E8-B48F-1D18A9856A87","full_name":"Synak, Peter","last_name":"Synak","first_name":"Peter"}],"date_updated":"2026-04-16T08:29:34Z","title":"Methods for fluid simulation, surface tracking, and statistics of non-manifold structures"},{"alternative_title":["ISTA Thesis"],"date_created":"2025-06-25T13:50:10Z","abstract":[{"text":"Cooperation, that is, one person paying a cost for another's benefit, is a fundamental principle without which no form of society could exist. The extent to which humans cooperate with each other is also an essential feature that differentiates them from other animals. Cooperation occurs even in the absence of altruistic motivations, when it is selfishly incentivised by the expectation of a future reward. For example, many economic interactions are well described that way. This kind of cooperation requires that people exhibit reciprocal behaviour that acts as a mechanism that rewards cooperation.\r\nWith game-theoretic models, it is possible to formally study potential such mechanisms and under what conditions they can exist. This thesis contributes to this effort by analysing recently introduced models of cooperation that advance on previous work by taking into account the potential for pre-existing inequality among cooperating individuals as well as the different forms that reciprocity can take.\r\nIndividuals may differ both intrinsically, in their abilities, as well as extrinsically, in the amount of resources they have available. Allowing for such differences in a model of cooperation helps to understand how inequality affects the potential for, and outcomes of, cooperation among unequals. In this thesis, it is shown that in the presence of intrinsic inequality, a similar unequal distribution of resources can increase the potential for cooperation. This effect is stronger the smaller the group is in which cooperation takes place. It is also shown that under particular assumptions, if the unequal members of a group vary the size of their contributions to a cooperative effort over time, they can thereby increase their efficiency and improve the collective outcome.\r\nCooperative behaviour in a two-person interaction can be rewarded either by direct reciprocation whenever the same two people interact again, or indirectly by a third party who observed the interaction. In the latter case of indirect reciprocity, individuals are proximally rewarded by a good reputation, which ultimately translates to being rewarded with cooperative behaviour by others. This mechanism can enable selfishly motivated cooperation even in circumstances where individuals are unlikely to meet again, akin to how money facilitates trade. While these two forms of reciprocity have mostly been studied in isolation, this thesis analyses both direct and indirect reciprocity in a general model in order to compare their relative effectiveness under different circumstances. The contribution of this thesis is an extension of previous work regarding a specific kind of interaction, whose parameters allow for convenient mathematical analysis, to the most general set of possible interactions.","lang":"eng"}],"has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","supervisor":[{"orcid":"0000-0002-4561-241X","last_name":"Chatterjee","first_name":"Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","full_name":"Chatterjee, Krishnendu"}],"language":[{"iso":"eng"}],"degree_awarded":"PhD","status":"public","corr_author":"1","ddc":["519"],"month":"06","page":"157","ec_funded":1,"type":"dissertation","oa":1,"year":"2025","article_processing_charge":"No","publication_status":"published","file":[{"file_size":6192760,"access_level":"closed","content_type":"application/x-xz","date_created":"2025-06-25T13:38:07Z","relation":"source_file","file_name":"Thesis Valentin Hübner source.tar.xz","checksum":"794c02f8c82ca59ba6dda3bd7eed871a","creator":"vhuebner","date_updated":"2025-06-25T13:38:07Z","file_id":"19905"},{"file_size":4837864,"access_level":"open_access","content_type":"application/pdf","date_created":"2025-07-09T13:37:00Z","relation":"main_file","file_name":"Thesis Valentin Hübner.pdf","checksum":"ac56063d81c81e40322b6ff5a8c4912e","creator":"vhuebner","date_updated":"2025-07-09T13:37:00Z","file_id":"19976"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_published":"2025-06-25T00:00:00Z","department":[{"_id":"GradSch"},{"_id":"KrCh"}],"project":[{"_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020","grant_number":"863818","name":"Formal Methods for Stochastic Models: Algorithms and Applications"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"}],"citation":{"apa":"Hübner, V. (2025). <i>Reciprocity and inequality in social dilemmas</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-19903\">https://doi.org/10.15479/AT-ISTA-19903</a>","ista":"Hübner V. 2025. Reciprocity and inequality in social dilemmas. Institute of Science and Technology Austria.","ama":"Hübner V. Reciprocity and inequality in social dilemmas. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19903\">10.15479/AT-ISTA-19903</a>","ieee":"V. Hübner, “Reciprocity and inequality in social dilemmas,” Institute of Science and Technology Austria, 2025.","mla":"Hübner, Valentin. <i>Reciprocity and Inequality in Social Dilemmas</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-19903\">10.15479/AT-ISTA-19903</a>.","short":"V. Hübner, Reciprocity and Inequality in Social Dilemmas, Institute of Science and Technology Austria, 2025.","chicago":"Hübner, Valentin. “Reciprocity and Inequality in Social Dilemmas.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-19903\">https://doi.org/10.15479/AT-ISTA-19903</a>."},"tmp":{"image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)"},"doi":"10.15479/AT-ISTA-19903","_id":"19903","oa_version":"Published Version","related_material":{"record":[{"relation":"part_of_dissertation","id":"19843","status":"public"},{"status":"public","id":"15083","relation":"part_of_dissertation"},{"id":"19074","relation":"part_of_dissertation","status":"public"}]},"file_date_updated":"2025-07-09T13:37:00Z","publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"The research for this thesis was supported by the European Research Council\r\n(grant agreements No. 863818 and No. 850529), the European Union’s Horizon 2020 research and innovation programme (Marie Skłodowska-Curie grant agreement No. 754411),\r\nthe Austrian Science Fund (grant DOI 10.55776/COE12), the French Agence Nationale\r\nde la Recherche under the Programme d’investissements d’avenir (project reference 17-\r\nEURE-0010) and the Australian Government through the Australian Research Council\r\n(grant No. SR200100005, “Securing Antarctica’s Environmental Future”).","day":"25","license":"https://creativecommons.org/licenses/by-nc/4.0/","OA_place":"publisher","author":[{"first_name":"Valentin","orcid":"0009-0001-5009-4987","last_name":"Hübner","id":"2c8aa207-dc7d-11ea-9b2f-f22972ecd910","full_name":"Hübner, Valentin"}],"date_updated":"2026-04-07T12:30:57Z","title":"Reciprocity and inequality in social dilemmas"},{"_id":"20117","oa_version":"Published Version","doi":"10.15479/AT-ISTA-20117","citation":{"chicago":"Wang, Yiqun. “The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20117\">https://doi.org/10.15479/AT-ISTA-20117</a>.","short":"Y. Wang, The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development, Institute of Science and Technology Austria, 2025.","mla":"Wang, Yiqun. <i>The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20117\">10.15479/AT-ISTA-20117</a>.","ieee":"Y. Wang, “The role of dynamin related protein 2A in cytokinin regulated plant growth and development,” Institute of Science and Technology Austria, 2025.","ama":"Wang Y. The role of dynamin related protein 2A in cytokinin regulated plant growth and development. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20117\">10.15479/AT-ISTA-20117</a>","apa":"Wang, Y. (2025). <i>The role of dynamin related protein 2A in cytokinin regulated plant growth and development</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20117\">https://doi.org/10.15479/AT-ISTA-20117</a>","ista":"Wang Y. 2025. The role of dynamin related protein 2A in cytokinin regulated plant growth and development. Institute of Science and Technology Austria."},"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"date_updated":"2026-04-07T11:49:34Z","title":"The role of dynamin related protein 2A in cytokinin regulated plant growth and development","author":[{"id":"82F537F2-B517-11E9-84D7-6433E6697425","full_name":"Wang, Yiqun","last_name":"Wang","first_name":"Yiqun"}],"OA_place":"publisher","file_date_updated":"2025-09-03T09:36:52Z","related_material":{"record":[{"status":"public","id":"18063","relation":"part_of_dissertation"}]},"acknowledgement":"I would also like to acknowledge the invaluable assistance provided by the Plant\r\nFacility, Imaging & Optics Facility, and the Lab Support Facility. The technical support and\r\nresources offered by these facilities were indispensable to the successful completion of my\r\nexperiments.","publication_identifier":{"issn":["2663-337X"]},"day":"04","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"corr_author":"1","status":"public","month":"08","ddc":["580"],"degree_awarded":"PhD","language":[{"iso":"eng"}],"supervisor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","last_name":"Benková","first_name":"Eva"}],"alternative_title":["ISTA Thesis"],"date_created":"2025-08-04T15:24:21Z","has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_published":"2025-08-04T00:00:00Z","article_processing_charge":"No","year":"2025","publication_status":"published","file":[{"file_id":"20209","date_updated":"2025-08-22T08:53:46Z","checksum":"36b87c17d12c7bf5955d6d812acb8d77","creator":"yiqwang","file_name":"2025_Wang_Yiqun_Thesis.docx","relation":"source_file","date_created":"2025-08-22T08:22:10Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","file_size":25798848},{"file_size":12628313,"access_level":"closed","content_type":"application/pdf","date_created":"2025-08-22T10:32:30Z","relation":"main_file","file_name":"2025_Wang_Yiqun_Thesis.pdf","creator":"yiqwang","checksum":"8d7a2383f66377da675d379ec30ea0fe","embargo_to":"open_access","date_updated":"2025-09-03T09:36:52Z","file_id":"20211","embargo":"2026-09-03"}],"type":"dissertation","page":"108"},{"day":"08","publication_identifier":{"issn":["2663-337X"]},"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"10703"},{"relation":"part_of_dissertation","id":"20082","status":"public"}]},"file_date_updated":"2025-08-27T13:02:28Z","acknowledgement":"I would like to acknowledge the\r\nfinancial support of the European Research Council through the ERC-SyG grant “Pushing from\r\nwithin: Control of cell shape, integrity and motility by cytoskeletal pushing forces”\r\n(01071793), which made this research possible. ","OA_place":"publisher","author":[{"first_name":"Patricia","orcid":"0000-0003-1681-508X","last_name":"Dos Reis Rodrigues","id":"26E95904-5160-11E9-9C0B-C5B0DC97E90F","full_name":"Dos Reis Rodrigues, Patricia"}],"title":"Coordination of protrusive forces in immune cell migration ","date_updated":"2026-04-28T13:26:50Z","department":[{"_id":"GradSch"},{"_id":"MiSi"}],"tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"doi":"10.15479/AT-ISTA-20149","citation":{"short":"P. Dos Reis Rodrigues, Coordination of Protrusive Forces in Immune Cell Migration , Institute of Science and Technology Austria, 2025.","chicago":"Dos Reis Rodrigues, Patricia. “Coordination of Protrusive Forces in Immune Cell Migration .” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20149\">https://doi.org/10.15479/AT-ISTA-20149</a>.","apa":"Dos Reis Rodrigues, P. (2025). <i>Coordination of protrusive forces in immune cell migration </i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20149\">https://doi.org/10.15479/AT-ISTA-20149</a>","ista":"Dos Reis Rodrigues P. 2025. Coordination of protrusive forces in immune cell migration . Institute of Science and Technology Austria.","ama":"Dos Reis Rodrigues P. Coordination of protrusive forces in immune cell migration . 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20149\">10.15479/AT-ISTA-20149</a>","mla":"Dos Reis Rodrigues, Patricia. <i>Coordination of Protrusive Forces in Immune Cell Migration </i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20149\">10.15479/AT-ISTA-20149</a>.","ieee":"P. Dos Reis Rodrigues, “Coordination of protrusive forces in immune cell migration ,” Institute of Science and Technology Austria, 2025."},"project":[{"_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd","grant_number":"101071793","name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces"}],"oa_version":"Published Version","_id":"20149","page":"114","oa":1,"type":"dissertation","file":[{"content_type":"application/pdf","access_level":"open_access","file_size":63885565,"file_name":"2025_ReisRodrigues_Patricia_Thesis.pdf","checksum":"fda8a1070667c3562263f4867609b41b","creator":"prodrigu","relation":"main_file","date_created":"2025-08-27T12:59:10Z","date_updated":"2025-08-27T12:59:10Z","file_id":"20232","success":1},{"file_size":50483434,"access_level":"closed","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_created":"2025-08-27T13:00:30Z","relation":"source_file","file_name":"2025_ReisRodrigues_Patricia_Thesis.docx","checksum":"e8b65affcbce846a926454df4b2867b9","creator":"prodrigu","date_updated":"2025-08-27T13:02:28Z","file_id":"20233"}],"publication_status":"published","article_processing_charge":"No","year":"2025","date_published":"2025-08-08T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","date_created":"2025-08-08T09:18:02Z","abstract":[{"text":"Immune responses depend on the coordinated and efficient migration of leukocytes. These\r\ncells, which are embedded and tightly confined within tissues, must navigate and traverse\r\ndiverse and complex three-dimensional environments. Leukocytes adapt their locomotory\r\nbehavior to the mechanical, geometrical, and biochemical characteristics of their\r\nsurroundings. In low-density environments, where the pore size of the interstitial matrix\r\nallows free passage, these cells position the nucleus directly behind the lamellipodium, the\r\nprotrusive actin structure that forms the leading front of the cell. In this configuration, they\r\nuse the nucleus as a gauge to identify the path of least resistance.\r\nHere, we show that in high-density environments, where the pore size precludes free passage\r\nof the cell body, leukocytes reposition the microtubule-organizing center (MTOC) and\r\nassociated organelles in front of the nucleus. In this configuration, they use actin structures\r\nprotruding orthogonally to the direction of migration in order to open a path for the cell body.\r\nWe identify two distinct actin populations that serve this purpose at different subcellular\r\nlocalizations. At the leading edge, local indentation of the plasma membrane leads to\r\nrecruitment of the Wiskott-Aldrich syndrome protein (WASp), which, via Arp2/3, results in\r\nthe formation of individual actin foci. At the cell body, actin polymerization is triggered by\r\nDOCK8, a Cdc42 exchange factor, resulting in the formation of a central actin pool.\r\nWe demonstrate that the central and peripheral actin pools are functionally communicating\r\nand that depletion of the central actin pool leads to increased actin accumulation at the cell\r\nfront, resulting in excessive extension of the leading edge.","lang":"eng"}],"alternative_title":["ISTA Thesis"],"supervisor":[{"orcid":"0000-0002-6620-9179","last_name":"Sixt","first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K"}],"language":[{"iso":"eng"}],"degree_awarded":"PhD","month":"08","status":"public","ddc":["570"],"corr_author":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"NanoFab"}]},{"date_updated":"2026-04-07T11:48:07Z","title":"Construction of a cryo-super-resolution microscope to guide in situ structure analysis","author":[{"id":"937696FA-C996-11E9-8C7C-CF13E6697425","full_name":"Vorlaufer, Jakob","first_name":"Jakob","orcid":"0009-0000-7590-3501","last_name":"Vorlaufer"}],"OA_place":"publisher","publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"The project was supported by CZI grant DAF2021-234754 and grant\r\nDOI: https://doi.org/10.37921/812628ebpcwg from the Chan Zuckerberg Initiative DAF, an\r\nadvised fund of Silicon Valley Community Foundation (funder\r\nDOI: https://doi.org/10.13039/100014989), as well as internal grants from ISTA’s Equipment\r\nInvestment Committee and Interdisciplinary Project Committee. ","file_date_updated":"2025-08-25T13:49:56Z","related_material":{"record":[{"status":"public","id":"19795","relation":"part_of_dissertation"}]},"day":"25","oa_version":"Published Version","_id":"20206","citation":{"short":"J. Vorlaufer, Construction of a Cryo-Super-Resolution Microscope to Guide in Situ Structure Analysis, Institute of Science and Technology Austria, 2025.","chicago":"Vorlaufer, Jakob. “Construction of a Cryo-Super-Resolution Microscope to Guide in Situ Structure Analysis.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20206\">https://doi.org/10.15479/AT-ISTA-20206</a>.","ista":"Vorlaufer J. 2025. Construction of a cryo-super-resolution microscope to guide in situ structure analysis. Institute of Science and Technology Austria.","ama":"Vorlaufer J. Construction of a cryo-super-resolution microscope to guide in situ structure analysis. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20206\">10.15479/AT-ISTA-20206</a>","apa":"Vorlaufer, J. (2025). <i>Construction of a cryo-super-resolution microscope to guide in situ structure analysis</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20206\">https://doi.org/10.15479/AT-ISTA-20206</a>","ieee":"J. Vorlaufer, “Construction of a cryo-super-resolution microscope to guide in situ structure analysis,” Institute of Science and Technology Austria, 2025.","mla":"Vorlaufer, Jakob. <i>Construction of a Cryo-Super-Resolution Microscope to Guide in Situ Structure Analysis</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20206\">10.15479/AT-ISTA-20206</a>."},"tmp":{"short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png"},"doi":"10.15479/AT-ISTA-20206","project":[{"grant_number":"CZI01","name":"CryoMinflux-guided in-situ molecular census and structure determination","_id":"62909c6f-2b32-11ec-9570-e1476aab5308"}],"department":[{"_id":"GradSch"},{"_id":"JoDa"}],"date_published":"2025-08-25T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","file":[{"date_created":"2025-08-25T13:49:55Z","relation":"source_file","creator":"jvorlauf","checksum":"191db3367c19c9b32b65f4bc3a7c19de","file_name":"2025_Vorlaufer_Jakob_Thesis.docx","file_size":39735535,"access_level":"closed","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_id":"20228","date_updated":"2025-08-25T13:49:55Z"},{"success":1,"file_id":"20229","date_updated":"2025-08-25T13:49:56Z","relation":"main_file","date_created":"2025-08-25T13:49:56Z","checksum":"104400e6036921569610230c1d4899dc","creator":"jvorlauf","file_name":"2025_Vorlaufer_Jakob_Thesis.pdf","file_size":10947446,"content_type":"application/pdf","access_level":"open_access"}],"year":"2025","article_processing_charge":"No","publication_status":"published","oa":1,"type":"dissertation","page":"107","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"EM-Fac"},{"_id":"Bio"}],"status":"public","corr_author":"1","ddc":["621","535"],"month":"08","degree_awarded":"PhD","language":[{"iso":"eng"}],"supervisor":[{"last_name":"Danzl","orcid":"0000-0001-8559-3973","first_name":"Johann G","full_name":"Danzl, Johann G","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87"}],"publisher":"Institute of Science and Technology Austria","alternative_title":["ISTA Thesis"],"date_created":"2025-08-22T08:12:55Z","abstract":[{"lang":"eng","text":"The internal structure of biomolecules and their organization in higher-order arrangements are key factors governing the working principles of biological systems. Bioimaging has successfully revealed arrangements across relevant spatial scales. For example, cryo-electron tomography has become widely used for analyzing biomolecular structures in situ due to its comprehensive structural visualization of near-natively preserved samples, and its capability of sub-nm resolution via averaging. However, the identification of molecules within crowded cellular environments is often hindered by low contrast. Fluorescence microscopy, on the other hand, routinely visualizes specifically labeled targets at single-molecule contrast against essentially zero background. Moreover, it provides comparatively high throughput and is amenable to multiplexing. Due to this complementarity, combining datasets from both modalities acquired on the same region via correlative light and electron microscopy can reveal novel types of information. \r\nThe spatial scale at which information can be extracted depends on imaging resolution and correlation accuracy. Since diffraction of light limits the resolution of conventional fluorescence microscopy to few hundreds of nanometers, reaching the full potential of correlative imaging requires super-resolution approaches. Performing imaging at cryogenic temperature preserves structures in a near-native state and minimizes distortions between the fluorescence and the electron microscopy datasets. Implementations of this concept have achieved correlation on the scale of cellular organelles or bacterial domains.\r\nWe have worked towards pushing correlative imaging to the single-molecule scale by improving cryo-super-resolution microscopy, and devising a refined image correlation workflow. As part of this project, I constructed a microscopy setup and adopted it for super-resolution fluorescence microscopy at room temperature and cryogenic conditions. I explored different cryo-stages and acquisition strategies. Specifically, I developed a new scheme for correcting sample drift, thus increasing mechanical stability during microscopy acquisitions.\r\n"}],"has_accepted_license":"1"},{"author":[{"last_name":"Babic","first_name":"David","full_name":"Babic, David","id":"db566d23-f6e0-11ea-865d-e6f270e968e7"}],"date_updated":"2026-04-07T11:52:02Z","title":"Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana","related_material":{"record":[{"id":"20187","relation":"part_of_dissertation","status":"public"}]},"publication_identifier":{"issn":["2663-337X"]},"file_date_updated":"2025-09-26T07:29:11Z","day":"18","OA_place":"publisher","oa_version":"Published Version","_id":"20362","department":[{"_id":"GradSch"},{"_id":"JiFr"},{"_id":"EvBe"}],"doi":"10.15479/AT-ISTA-20362","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"chicago":"Babic, David. “Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis Thaliana.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20362\">https://doi.org/10.15479/AT-ISTA-20362</a>.","short":"D. Babic, Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis Thaliana, Institute of Science and Technology Austria, 2025.","ieee":"D. Babic, “Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana,” Institute of Science and Technology Austria, 2025.","mla":"Babic, David. <i>Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis Thaliana</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20362\">10.15479/AT-ISTA-20362</a>.","apa":"Babic, D. (2025). <i>Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20362\">https://doi.org/10.15479/AT-ISTA-20362</a>","ama":"Babic D. Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20362\">10.15479/AT-ISTA-20362</a>","ista":"Babic D. 2025. Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana. 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This work would not have been possible without the contribution and support of people\r\nbehind the scientific service units at ISTA: the Life Science Facility (LSF), Imaging and\r\nOptics Facility (IOF), the Bioinformatics Unit, Protein Services Unit and\r\nElectrophysiology Unit. I would also like to recognize the work of people at the Vienna\r\nBiocenter (VBC) Mass Spectrometry Facility, particularly Markus Hartl and WeiQiang\r\nChen. ","day":"23","OA_place":"publisher","oa_version":"Published Version","_id":"20485","department":[{"_id":"GradSch"},{"_id":"MaDe"}],"doi":"10.15479/AT-ISTA-20485","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"chicago":"Misova, Michaela. “Dissecting Gap Junction Biology Using the C. 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This thesis explores geometric structures and dynamics on this space, with emphasis on their implications for physics, particularly hydrodynamics.\r\n\r\nOur investigation ranges from theoretical studies of infinite-dimensional symplectic and prequantum geometry to numerical computation of the time evolution of shapes. The thesis presents four main contributions.\r\n\r\nIn the first part, we introduce implicit representations of codimension-2 shapes using a class of complex-valued functions, and prove that the space of these implicit representations forms a prequantum bundle over the codimension-2 shape space. This reveals a new geometric interpretation of the canonical symplectic structure on the codimension-2 shape space.\r\n\r\nIn the second part, we use implicit representations to develop a simulation method for the dynamics of space curves. To handle chaotic systems such as vortex filaments in hydrodynamics, we exploit the infinite degrees of freedom, hidden in both the configuration and dynamics of implicit representations.\r\n\r\nIn the third part, we introduce new symplectic structures on the space of space curves, which generalize the only previously known symplectic structure on this space, allowing for new Hamiltonian dynamics of space curves.\r\n\r\nIn the fourth part, we apply a symplectic viewpoint to a differential geometric problem with practical applications. We derive a new area formula for spherical polygons via prequantization. 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Ishida, Symplectic-Prequantum Structures and Dynamics on the Codimension-2 Shape Space, Institute of Science and Technology Austria, 2025.","chicago":"Ishida, Sadashige. “Symplectic-Prequantum Structures and Dynamics on the Codimension-2 Shape Space.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20551\">https://doi.org/10.15479/AT-ISTA-20551</a>.","ama":"Ishida S. Symplectic-prequantum structures and dynamics on the codimension-2 shape space. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20551\">10.15479/AT-ISTA-20551</a>","ista":"Ishida S. 2025. Symplectic-prequantum structures and dynamics on the codimension-2 shape space. Institute of Science and Technology Austria.","apa":"Ishida, S. (2025). <i>Symplectic-prequantum structures and dynamics on the codimension-2 shape space</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20551\">https://doi.org/10.15479/AT-ISTA-20551</a>","mla":"Ishida, Sadashige. <i>Symplectic-Prequantum Structures and Dynamics on the Codimension-2 Shape Space</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20551\">10.15479/AT-ISTA-20551</a>.","ieee":"S. Ishida, “Symplectic-prequantum structures and dynamics on the codimension-2 shape space,” Institute of Science and Technology Austria, 2025."},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.15479/AT-ISTA-20551","project":[{"call_identifier":"H2020","_id":"2533E772-B435-11E9-9278-68D0E5697425","name":"Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large Scales","grant_number":"638176"},{"grant_number":"101045083","name":"Computational Discovery of Numerical Algorithms for Animation and Simulation of Natural Phenomena","_id":"34bc2376-11ca-11ed-8bc3-9a3b3961a088"}],"department":[{"_id":"GradSch"},{"_id":"ChWo"}],"title":"Symplectic-prequantum structures and dynamics on the codimension-2 shape space","date_updated":"2026-04-07T12:02:23Z","author":[{"first_name":"Sadashige","orcid":"0000-0002-3121-3100","last_name":"Ishida","id":"6F7C4B96-A8E9-11E9-A7CA-09ECE5697425","full_name":"Ishida, Sadashige"}],"OA_place":"publisher","day":"31","publication_identifier":{"isbn":["978-3-99078-070-1"],"issn":["2663-337X"]},"related_material":{"record":[{"status":"public","id":"12846","relation":"part_of_dissertation"},{"status":"public","id":"12431","relation":"part_of_dissertation"},{"id":"17361","relation":"part_of_dissertation","status":"public"},{"id":"20580","relation":"part_of_dissertation","status":"public"}]},"file_date_updated":"2025-11-10T08:45:05Z","acknowledgement":"Projects contained in this thesis were financially supported in part by the\r\nEuropean Research Council with grants 1. ERC Consolidator Grant 101045083 CoDiNA,\r\nand 2. the European Union’s Horizon 2020 research and innovation programme under grant\r\nagreement No. 638176."},{"date_published":"2025-11-03T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","file":[{"checksum":"6a0487b2b66bb35d44b394756d44b8b4","creator":"vriabov","file_name":"riabov_thesis-pdfa.pdf","date_created":"2025-10-29T18:53:59Z","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_size":7536583,"success":1,"file_id":"20577","date_updated":"2025-10-29T18:53:59Z"},{"file_id":"20578","date_updated":"2025-10-29T18:54:53Z","date_created":"2025-10-29T18:54:53Z","relation":"source_file","checksum":"224efda6bf9864d296a1e5e0124c1e8f","creator":"vriabov","file_name":"manuscript.zip","file_size":17841612,"access_level":"closed","content_type":"application/x-zip-compressed"}],"year":"2025","article_processing_charge":"No","publication_status":"published","oa":1,"type":"dissertation","ec_funded":1,"page":"436","status":"public","month":"11","corr_author":"1","ddc":["515","519"],"degree_awarded":"PhD","language":[{"iso":"eng"}],"supervisor":[{"first_name":"László","last_name":"Erdös","orcid":"0000-0001-5366-9603","full_name":"Erdös, László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"}],"publisher":"Institute of Science and Technology Austria","alternative_title":["ISTA Thesis"],"abstract":[{"lang":"eng","text":"This thesis deals with eigenvalue and eigenvector universality results for random matrix ensembles equipped with non-trivial spatial structure. We consider both mean-field models with a general variance profile (Wigner-type matrices) and correlation structure (correlated matrices) among the entries, as well as non-mean-field random band matrices with bandwidth W >> N^(1/2).\r\n\r\nTo extract the universal properties of random matrix spectra and eigenvectors, we obtain concentration estimates for their resolvent, the local laws, which generalize the celebrated Wigner semicircle law for a broad class of random matrices to much finer spectral scales. The local laws hold for both a single resolvent as well as for products of multiple resolvents, known as resolvent chains, and express the remarkable approximately-deterministic behavior of these objects down to the microscopic scale.\r\n\r\nOur primary tool for establishing the local laws is the dynamical Zigzag strategy, which we develop in the setting of spatially-inhomogeneous random matrices. Our proof method systematically addresses the challenges arising from non-trivial spatial structures and is robust to all types of singularities in the spectrum, as we demonstrate in the correlated setting. Furthermore, we incorporate the analysis of the deterministic resolvent chain approximations into the dynamical framework of the Zigzag strategy, synthesizing a unified toolkit for establishing multi-resolvent local laws.\r\n\r\nUsing these methods, we prove complete eigenvector delocalization, the Eigenstate Thermalization Hypothesis, and Wigner-Dyson universality in the bulk for random band matrices down to the optimal bandwidth W >> N^(1/2). For mean-field ensembles, we establish universality of local eigenvalue statistics at the cups for random matrices with correlated entries, and the Eigenstate Thermalization Hypothesis for Wigner-type matrices in the bulk of the spectrum.\r\n\r\nFinally, this thesis also contains other applications of the multi-resolvent local laws to spatially-inhomogeneous random matrices, obtained prior to the development of the Zigzag strategy. In particular, we provide a complete analysis of mesoscopic linear-eigenvalue statistics of Wigner-type matrices in all spectral regimes, including the novel cusps, and rigorously establish the prethermalization phenomenon for deformed Wigner matrices.\r\n\r\nThe main body of this thesis consists of seven research papers (listed on page xi), each presented in a separate chapter with its own introduction and all relevant context, suitable to be read independently. We ask the reader’s indulgence for the repetitions in the historical overviews and other minor redundancies that remain among the chapters as a result. The overall Introduction, preceding the chapters, provides a condensed, informal summary of the main ideas and concepts at the core of these works.\r\n"}],"date_created":"2025-10-29T19:12:24Z","has_accepted_license":"1","date_updated":"2026-04-07T12:32:20Z","title":"Universality in random matrices with spatial structure","author":[{"last_name":"Riabov","first_name":"Volodymyr","full_name":"Riabov, Volodymyr","id":"1949f904-edfb-11eb-afb5-e2dfddabb93b"}],"OA_place":"publisher","acknowledgement":"The work comprising this thesis was supported by the ERC Advanced Grant \"RMTBeyond\"\r\nNo.101020331 awarded to my advisor.","file_date_updated":"2025-10-29T18:54:53Z","related_material":{"record":[{"status":"public","id":"20322","relation":"part_of_dissertation"},{"id":"18764","relation":"part_of_dissertation","status":"public"},{"id":"13317","relation":"part_of_dissertation","status":"public"},{"id":"19368","relation":"part_of_dissertation","status":"deleted"},{"id":"18554","relation":"part_of_dissertation","status":"public"},{"id":"20576","relation":"part_of_dissertation","status":"public"},{"relation":"part_of_dissertation","id":"17174","status":"public"},{"relation":"part_of_dissertation","id":"19547","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"19598"}]},"publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-064-0"]},"day":"3","oa_version":"Published Version","_id":"20575","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"apa":"Riabov, V. (2025). <i>Universality in random matrices with spatial structure</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20575\">https://doi.org/10.15479/AT-ISTA-20575</a>","ista":"Riabov V. 2025. Universality in random matrices with spatial structure. Institute of Science and Technology Austria.","ama":"Riabov V. Universality in random matrices with spatial structure. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20575\">10.15479/AT-ISTA-20575</a>","mla":"Riabov, Volodymyr. <i>Universality in Random Matrices with Spatial Structure</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20575\">10.15479/AT-ISTA-20575</a>.","ieee":"V. Riabov, “Universality in random matrices with spatial structure,” Institute of Science and Technology Austria, 2025.","short":"V. Riabov, Universality in Random Matrices with Spatial Structure, Institute of Science and Technology Austria, 2025.","chicago":"Riabov, Volodymyr. “Universality in Random Matrices with Spatial Structure.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20575\">https://doi.org/10.15479/AT-ISTA-20575</a>."},"doi":"10.15479/AT-ISTA-20575","project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","call_identifier":"H2020","grant_number":"101020331","name":"Random matrices beyond Wigner-Dyson-Mehta"}],"department":[{"_id":"GradSch"},{"_id":"LaEr"}]},{"author":[{"first_name":"Raquel","last_name":"Casado Polanco","orcid":"0000-0001-8293-4568","full_name":"Casado Polanco, Raquel","id":"15240fc1-dbcd-11ea-9d1d-ac5a786425fd"}],"date_updated":"2026-04-14T08:16:58Z","title":"Role of NOTCH signaling in radial glial progenitor lineage progression","acknowledgement":"I also want to thank ISTA and the Austrian Science Fund FWF SFB F78 (F7805) for financially\r\nsupporting my research.","file_date_updated":"2025-12-11T11:18:37Z","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-072-5"]},"day":"09","OA_place":"publisher","oa_version":"Published Version","_id":"20737","department":[{"_id":"GradSch"},{"_id":"SiHi"}],"doi":"10.15479/AT-ISTA-20737","citation":{"short":"R. Casado Polanco, Role of NOTCH Signaling in Radial Glial Progenitor Lineage Progression, Institute of Science and Technology Austria, 2025.","chicago":"Casado Polanco, Raquel. “Role of NOTCH Signaling in Radial Glial Progenitor Lineage Progression.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20737\">https://doi.org/10.15479/AT-ISTA-20737</a>.","apa":"Casado Polanco, R. (2025). <i>Role of NOTCH signaling in radial glial progenitor lineage progression</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20737\">https://doi.org/10.15479/AT-ISTA-20737</a>","ama":"Casado Polanco R. Role of NOTCH signaling in radial glial progenitor lineage progression. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20737\">10.15479/AT-ISTA-20737</a>","ista":"Casado Polanco R. 2025. Role of NOTCH signaling in radial glial progenitor lineage progression. Institute of Science and Technology Austria.","ieee":"R. Casado Polanco, “Role of NOTCH signaling in radial glial progenitor lineage progression,” Institute of Science and Technology Austria, 2025.","mla":"Casado Polanco, Raquel. <i>Role of NOTCH Signaling in Radial Glial Progenitor Lineage Progression</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20737\">10.15479/AT-ISTA-20737</a>."},"project":[{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","grant_number":"F7805"}],"file":[{"file_id":"20793","date_updated":"2025-12-11T11:18:37Z","creator":"rcasadop","checksum":"71e0fdf4619b0d70d03657ad7348137d","file_name":"2025_CasadoPolanco_Raquel_Thesis.docx","relation":"source_file","date_created":"2025-12-11T09:28:09Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","file_size":78207207},{"file_id":"20794","embargo":"2026-12-01","date_updated":"2025-12-11T09:28:04Z","embargo_to":"open_access","checksum":"58cf2f25c33567723bc754a019c3e396","file_name":"2025_CasadoPolanco_Raquel_Thesis.pdf","creator":"rcasadop","date_created":"2025-12-11T09:28:04Z","relation":"main_file","access_level":"closed","content_type":"application/pdf","file_size":6261874}],"keyword":["NOTCH","radial glial progenitor","lineage progression","cortical development"],"article_processing_charge":"No","year":"2025","publication_status":"published","date_published":"2025-12-09T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"133","type":"dissertation","degree_awarded":"PhD","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"corr_author":"1","status":"public","month":"12","ddc":["570"],"publisher":"Institute of Science and Technology Austria","alternative_title":["ISTA Thesis"],"has_accepted_license":"1","date_created":"2025-12-09T09:04:18Z","supervisor":[{"full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","first_name":"Simon"}],"language":[{"iso":"eng"}]},{"date_published":"2025-12-09T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","file":[{"file_size":142876975,"access_level":"closed","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_created":"2025-12-10T13:09:58Z","relation":"source_file","creator":"mkojic","checksum":"a3643d07e93134b2490a566b02a4517d","file_name":"2025_marko_kojic_thesis.docx","date_updated":"2025-12-10T13:09:58Z","file_id":"20774"},{"date_updated":"2025-12-10T13:09:38Z","file_id":"20775","success":1,"file_size":8597045,"access_level":"open_access","content_type":"application/pdf","date_created":"2025-12-10T13:09:38Z","relation":"main_file","file_name":"2025_marko_kojic_thesis.pdf","checksum":"0a096f0af6ccc3a8329d5bb8797ad533","creator":"mkojic"}],"year":"2025","article_processing_charge":"No","publication_status":"published","oa":1,"type":"dissertation","acknowledged_ssus":[{"_id":"Bio"}],"ddc":["572"],"status":"public","corr_author":"1","month":"12","degree_awarded":"PhD","supervisor":[{"first_name":"Martin","last_name":"Loose","orcid":"0000-0001-7309-9724","full_name":"Loose, Martin","id":"462D4284-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","alternative_title":["ISTA Thesis"],"has_accepted_license":"1","abstract":[{"lang":"eng","text":"Life on Earth emerged when biomacromolecules were membrane-enclosed in a confined space where many essential chemical reactions were more likely to happen and thereby accelerate evolution. These kinds of membranes separated internal reactions from the outside chaos while staying flexible so that those primordial cells can move, adopt their shape and, most importantly, propagate. Such membrane plasticity still remains a defining feature of all modern cell types. This remarkable ability to change their shape is most prominently observed during their propagation (i.e., cell division). Throughout division, a cell undergoes drastic change in its shape, usually at the middle of the cell, pulling the two opposite membrane sides inward, closer to each other, and, finally, culminating in pinching off to separate the cell into two daughter cells. To achieve this, a cell needs to employ a protein machinery, usually termed divisome, that can coordinate all necessary intracellular processes with membrane remodelling and synthesis of other extracellular structures that decorate a cell. The focus of this dissertation is a membrane-remodelling FtsZ system that is present across all domains of life. FtsZ forms filaments that further self-organize into ring-like structures at the cell septum and together with other division proteins perform cell envelope synthesis and constriction. However, there are still knowledge gaps in our mechanistic understanding of division in both archaea and bacteria. My work presented in this dissertation centres around a simple yet not well understood question: How is the divisome positioned correctly at the mid-cell? To achieve the proper positioning, the divisome needs to (i) be recruited to the mid-cell and (ii) localized orthogonally to the long cell axis. I tackle these processes in two different systems by applying an in vitro biochemical bottom-up reconstitution approach. I use purified components of Haloferax volcanii and Escherichia coli divisome to explore how divisome is recruited to the mid-cell in archaea and how the Z-ring positions orthogonally to the long cell axis in bacteria, respectively. \r\n\r\nFirstly, I collaborate with archaeal cell and structural biologists to explore the assembly of early division proteins in two FtsZ-containing archaeon H. volcanii, a standard model system for understudied archaeal organisms. I particularly address the hierarchy of interactions that allow a tripartite complex formation (SepF-CdpB1-CdpB2) and how the hierarchy of interactions ultimately leads to the recruitment of FtsZ filaments to the septum. This part of work has been published in (Nußbaum et al., 2024). In collaboration with evolutionary biologists, I shed light on ancient features that archaeal divisome has retained to this day and also speculate on a property that it might have lost during the course of evolution. \r\n\r\nNext, I switch my attention to E. coli divisome. Particularly, I address the FtsZ’s intrinsic biophysical property that drives the Z-ring diameter, and thereby the perpendicular orientation of the Z-ring to the long cell axis based on suggested membrane curvature sensing mechanism (Vanhille-Campos et al., 2024). This property allows formation of different Z-ring diameters that match the variety of cell diameters present in prokaryotes. The results showcase that the distribution of charged amino acids in the intrinsically disordered linker at the C-terminus (CTL) of FtsZ is the major determining factor of Z-ring diameter with inter-CTL interactions as an underlying mechanism. \r\n\r\nFinally, I thoroughly explain the methodology I used to address the abovementioned projects, and I finish with a discussion on how early archaeal divisome assembly and curvature sensing mechanism in bacteria, at first sight unrelated topics, are interconnected and important groundwork for both fundamental and translational research. "}],"date_created":"2025-12-09T13:08:11Z","date_updated":"2026-04-07T12:27:58Z","title":"Towards understanding the assembly mechanisms of the Z-ring in Archaea and Bacteria","author":[{"orcid":"0000-0001-7244-8128","last_name":"Kojic","first_name":"Marko","id":"73e7ecd4-dc85-11ea-9058-88a16394b160","full_name":"Kojic, Marko"}],"OA_place":"publisher","file_date_updated":"2025-12-10T13:09:58Z","publication_identifier":{"isbn":["978-3-99078-073-2"],"issn":["2663-337X"]},"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"15118"}]},"day":"09","oa_version":"Published Version","_id":"20741","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"apa":"Kojic, M. (2025). <i>Towards understanding the assembly mechanisms of the Z-ring in Archaea and Bacteria</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20741\">https://doi.org/10.15479/AT-ISTA-20741</a>","ista":"Kojic M. 2025. Towards understanding the assembly mechanisms of the Z-ring in Archaea and Bacteria. Institute of Science and Technology Austria.","ama":"Kojic M. Towards understanding the assembly mechanisms of the Z-ring in Archaea and Bacteria. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20741\">10.15479/AT-ISTA-20741</a>","mla":"Kojic, Marko. <i>Towards Understanding the Assembly Mechanisms of the Z-Ring in Archaea and Bacteria</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20741\">10.15479/AT-ISTA-20741</a>.","ieee":"M. Kojic, “Towards understanding the assembly mechanisms of the Z-ring in Archaea and Bacteria,” Institute of Science and Technology Austria, 2025.","short":"M. Kojic, Towards Understanding the Assembly Mechanisms of the Z-Ring in Archaea and Bacteria, Institute of Science and Technology Austria, 2025.","chicago":"Kojic, Marko. “Towards Understanding the Assembly Mechanisms of the Z-Ring in Archaea and Bacteria.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20741\">https://doi.org/10.15479/AT-ISTA-20741</a>."},"doi":"10.15479/AT-ISTA-20741","department":[{"_id":"GradSch"},{"_id":"MaLo"}]}]