---
OA_place: publisher
_id: '19759'
abstract:
- lang: eng
  text: "Despite generating remarkable results in various computer vision tasks, deep
    learning comes\r\nwith some surprising shortcomings. For example, tiny perturbations,
    often imperceptible to\r\nthe human eye, can completely change the predictions
    of image classifiers. Despite a decade\r\nof research, the field has made limited
    progress in developing image classifiers that are both\r\naccurate and robust.
    This thesis aims to address this gap.\r\nAs our first contribution, we aim to
    simplify the process of training certifiably robust image\r\nclassifiers. We do
    this by designing a convolutional layer that does not require executing an\r\niterative
    procedure in every forward pass, but relies on an explicit bound instead. We also\r\npropose
    a loss function that allows optimizing for a particular margin more precisely.\r\nNext,
    we provide an overview and comparison of various methods that create robust image\r\nclassifiers
    by constraining the Lipschitz constant. This is important since generally longer\r\ntraining
    times and more parameters improve the performance of robust classifiers, making
    it\r\nchallenging to determine the most practical and effective methods from existing
    literature.\r\nIn 1-Lipschitz classification, the performance of current methods
    is still much worse than what\r\nwe expect on the simple tasks we consider. Therefore,
    we next investigate potential causes of\r\nthis shortcoming. We first consider
    the role of the activation function. We prove a theoretical\r\nshortcoming of
    the commonly used activation function, and provide an alternative without it.\r\nHowever
    this theoretical improvement does barely translate to the empirical performance
    of\r\nrobust classifiers, suggesting a different bottleneck.\r\nTherefore, in
    the final chapter, we study how the performance depends on the amount of\r\ntraining
    data. We prove that in the worst case, we might require far more data to train
    a\r\nrobust classifier compared to a normal one. We furthermore find that the
    amount of training\r\ndata is a key determinant of the performance current methods
    achieve on popular datasets.\r\nAdditionally, we show that linear subspaces exist
    with tiny data variance, and yet we can\r\nstill train very accurate classifiers
    after projecting into those subspaces. This shows that on\r\nthe datasets considered,
    enforcing robustness in classification makes the task strictly more\r\nchallenging.\r\n\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Bernd
  full_name: Prach, Bernd
  id: 2D561D42-C427-11E9-89B4-9C1AE6697425
  last_name: Prach
citation:
  ama: Prach B. Robust image classification with 1-Lipschitz networks. 2025. doi:<a
    href="https://doi.org/10.15479/10.15479/at-ista-19759">10.15479/10.15479/at-ista-19759</a>
  apa: Prach, B. (2025). <i>Robust image classification with 1-Lipschitz networks</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/10.15479/at-ista-19759">https://doi.org/10.15479/10.15479/at-ista-19759</a>
  chicago: Prach, Bernd. “Robust Image Classification with 1-Lipschitz Networks.”
    Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/10.15479/at-ista-19759">https://doi.org/10.15479/10.15479/at-ista-19759</a>.
  ieee: B. Prach, “Robust image classification with 1-Lipschitz networks,” Institute
    of Science and Technology Austria, 2025.
  ista: Prach B. 2025. Robust image classification with 1-Lipschitz networks. Institute
    of Science and Technology Austria.
  mla: Prach, Bernd. <i>Robust Image Classification with 1-Lipschitz Networks</i>.
    Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/10.15479/at-ista-19759">10.15479/10.15479/at-ista-19759</a>.
  short: B. Prach, Robust Image Classification with 1-Lipschitz Networks, Institute
    of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-05-28T16:20:48Z
date_published: 2025-05-30T00:00:00Z
date_updated: 2026-07-27T12:47:44Z
day: '30'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ChLa
doi: 10.15479/10.15479/at-ista-19759
doi_confirm: '1'
file:
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  date_updated: 2025-06-10T18:11:05Z
  file_id: '19829'
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has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '84'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publisher_comment: "In reference to IEEE copyrighted material which is used with permission
  in this thesis, the IEEE does not\r\nendorse any of ISTA's products or services.
  Internal or personal use of this\r\nmaterial is permitted. If interested in reprinting/republishing
  IEEE copyrighted material for advertising or promotional\r\npurposes or for creating
  new collective works for resale or redistribution, please go to\r\nhttp://www.ieee.org/publications_standards/publications/rights/rights_link.html
  to learn how to obtain a License from\r\nRightsLink.  If applicable, University
  Microfilms and/or ProQuest Library, or the Archives of Canada may supply single
  copies of the dissertation."
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supervisor:
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
title: Robust image classification with 1-Lipschitz networks
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20138'
abstract:
- lang: eng
  text: "The evolution shapes the world around us.\r\nNot only in biology, where the
    fittest individuals spread their genes but also in physics and social dynamics,
    the evolutionary forces determine the development of a state of matter or public
    opinions.\r\nMany models describe these dynamics.\r\nThis thesis examines the
    role of the structure in the models of selection.\r\nThe population structure
    is represented as a graph or a network, and each vertex is occupied by one individual.\r\nEvery
    individual has a type and fitness that represents the reproductive potential and
    depends on the type, occupied vertex, and the arrangement of the neighbors.\r\nThe
    evolution is modeled in discrete steps; in one step, one individual is replaced
    by a neighbor selected randomly with the influence of fitness.\r\n\r\n\r\n\r\nThe
    role of the networks is widely examined in the literature.\r\nThe structures that
    promote the spread of the desired type compared to the structureless case are
    called amplifiers.\r\nThe existence of amplifiers in various settings is an intensively
    studied topic, and in some settings, the amplifiers have been identified.\r\nMoreover,
    there are other important questions about the number of steps until one type spreads
    over the whole network (fixation time), the computational complexity, and the
    questions about the robustness of these processes.\r\n\r\n\r\nThis thesis explores
    the role of structure in evolution from many perspectives.\r\nFirst, it introduces
    different models and various choices that can be made in the models of evolution.\r\nIt
    highlights the role of the structure in the real world and how this is reflected
    in these models.\r\nThen, it describes the previous results and open problems.\r\nSecond,
    the thesis describes an amplifier for two variants of the Moran process: one with
    a constant birth rate and the other with a constant death rate.\r\nThis is an
    important contribution to the robustness of the amplification.\r\nThird, the thesis
    determines the complexity of spatial games.\r\nThese are processes where the fitness
    comes from a game, and the strength of selection is high.\r\nIt shows that determining
    the fate of cooperation in these games is a PSPACE-complete problem.\r\nFourth,
    the thesis describes the amplifier of cooperation for spatial games.\r\nThis is
    the first amplifier in this setting.\r\nFifth, the thesis examines the coexistence
    in the Moran process with environmental heterogeneity.\r\nIn this setting, the
    fitness depends not only on the type of the individual but also on the occupied
    vertex.\r\nThe chapter determines the relationship between the interactions of
    vertices of different types and the coexistence time.\r\nSixth, the thesis examines
    the social balance on networks and proposes a stochastic dynamic partially aware
    of the state of the graph, which reaches a balanced position quickly.\r\nFinally,
    the thesis presents conclusions and outlines the directions for future work.\r\n\r\n\r\n"
acknowledgement: "This work was supported by the European Research Council CoG 863818
  (ForMSMArt) and Austrian Science Fund 10.55776/COE12.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jakub
  full_name: Svoboda, Jakub
  id: 130759D2-D7DD-11E9-87D2-DE0DE6697425
  last_name: Svoboda
  orcid: 0000-0002-1419-3267
citation:
  ama: Svoboda J. Structural properties of games on graphs. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20138">10.15479/AT-ISTA-20138</a>
  apa: Svoboda, J. (2025). <i>Structural properties of games on graphs</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20138">https://doi.org/10.15479/AT-ISTA-20138</a>
  chicago: Svoboda, Jakub. “Structural Properties of Games on Graphs.” Institute of
    Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20138">https://doi.org/10.15479/AT-ISTA-20138</a>.
  ieee: J. Svoboda, “Structural properties of games on graphs,” Institute of Science
    and Technology Austria, 2025.
  ista: Svoboda J. 2025. Structural properties of games on graphs. Institute of Science
    and Technology Austria.
  mla: Svoboda, Jakub. <i>Structural Properties of Games on Graphs</i>. Institute
    of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20138">10.15479/AT-ISTA-20138</a>.
  short: J. Svoboda, Structural Properties of Games on Graphs, Institute of Science
    and Technology Austria, 2025.
corr_author: '1'
das_tickbox: '1'
date_created: 2025-08-05T14:33:59Z
date_published: 2025-08-05T00:00:00Z
date_updated: 2026-07-27T12:52:04Z
day: '05'
ddc:
- '000'
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrCh
doi: 10.15479/AT-ISTA-20138
doi_confirm: '1'
ec_funded: 1
file:
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has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '08'
oa: 1
oa_version: Published Version
page: '167'
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publisher_comment: "Chapter 4 is copyrighted by CC BY-NC-ND\r\n4.0, which prohibits
  derivatives. Chapter 6 is copyrighted: Copyright (2025) by the American\r\nPhysical
  Society. For a copy, redistribution, or modification needs to be permitted by the\r\nAmerican
  Physical Society.\r\n"
related_material:
  record:
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    relation: part_of_dissertation
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    relation: part_of_dissertation
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status: public
supervisor:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
title: Structural properties of games on graphs
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  short: CC BY-NC-SA (4.0)
type: dissertation
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...
---
OA_place: publisher
_id: '20607'
acknowledged_ssus:
- _id: Bio
- _id: SSU
- _id: LifeSc
- _id: M-Shop
acknowledgement: "I gratefully acknowledge the support of the ISTA Graduate School
  and the Scientific Service Units of\r\nISTA, whose resources made this work possible—especially
  the Imaging & Optics Facility, the Lab\r\nSupport Facility, and the Miba Machine
  Shop. I would like to thank two staff scientists in particular:\r\nRobert Hauschild
  (Imaging & Optics Facility) and Daniel Balazs (Lab Support Facility), for their\r\nassistance
  and advice. My PhD was partially funded by the Austrian Science Fund (FWF)\r\n(10.55776/P37169
  and 10.55776/COE5)."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Soumyadip
  full_name: Mondal, Soumyadip
  id: d25d21ef-dc8d-11ea-abe3-ec4576307f48
  last_name: Mondal
citation:
  ama: 'Mondal S. Oxygen and sulfur redox: Conversion kinetics and phase equilibria.
    2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20607">10.15479/AT-ISTA-20607</a>'
  apa: 'Mondal, S. (2025). <i>Oxygen and sulfur redox: Conversion kinetics and phase
    equilibria</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20607">https://doi.org/10.15479/AT-ISTA-20607</a>'
  chicago: 'Mondal, Soumyadip. “Oxygen and Sulfur Redox: Conversion Kinetics and Phase
    Equilibria.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20607">https://doi.org/10.15479/AT-ISTA-20607</a>.'
  ieee: 'S. Mondal, “Oxygen and sulfur redox: Conversion kinetics and phase equilibria,”
    Institute of Science and Technology Austria, 2025.'
  ista: 'Mondal S. 2025. Oxygen and sulfur redox: Conversion kinetics and phase equilibria.
    Institute of Science and Technology Austria.'
  mla: 'Mondal, Soumyadip. <i>Oxygen and Sulfur Redox: Conversion Kinetics and Phase
    Equilibria</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20607">10.15479/AT-ISTA-20607</a>.'
  short: 'S. Mondal, Oxygen and Sulfur Redox: Conversion Kinetics and Phase Equilibria,
    Institute of Science and Technology Austria, 2025.'
corr_author: '1'
das_tickbox: '1'
date_created: 2025-11-07T12:40:54Z
date_published: 2025-09-19T00:00:00Z
date_updated: 2026-07-29T12:57:15Z
day: '19'
ddc:
- '541'
- '543'
- '542'
degree_awarded: PhD
department:
- _id: GradSch
- _id: StFr
doi: 10.15479/AT-ISTA-20607
doi_confirm: '1'
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language:
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oa_version: Published Version
page: '71'
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- _id: 8df062be-16d5-11f0-9cad-f559b6612c7e
  grant_number: P37169
  name: Singlet oxygen in non-aqueous oxygen redox chemistry
publication_identifier:
  isbn:
  - 978-3-99078-071-8
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: part_of_dissertation
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status: public
supervisor:
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
title: 'Oxygen and sulfur redox: Conversion kinetics and phase equilibria'
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type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
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...
---
OA_place: publisher
_id: '20811'
abstract:
- lang: eng
  text: "\tThis thesis is organized into two parts, each comprising two chapters:
    Chapter 1 and 2 offer models for the evolution of vaccine resistance in response
    to diverse vaccination strategies. Chapter 3 and 4 review the statistics of records,
    their connection to models of innovation and an application to the cultural evolution
    of sports.\r\n\tIn chapter 1 we present a modelling study from 2021 on the evolution
    of SARS-CoV-2. At that time the vaccine-resistant Omicron variant had not yet
    evolved. In our model we consider a population that is becoming vaccinated over
    time, while a pathogen is spreading in the population and eventually becoming
    resistant to the vaccine. We explore effective pharmaceutical and non-pharmaceutical
    interventions to prevent the emergence of vaccine resistance. \r\n\tIn chapter
    2 we model a particular set of complex vaccination strategies, mosaic and pyramid
    vaccination, where an immunologically diverse portfolio of vaccines is considered.
    We find that a bet-hatching strategy, in which vaccine types are distributed in
    the population, is effective at hindering the evolution of vaccine resistance
    if mutation rates are high. \r\n\tIn chapter 3 we switch gears and present a review
    on the statistics of records. We highlight similarities and analogies to other
    models in the fields of statistical physics, evolution and innovation. This offers
    interesting complimentary perspectives on well-known models. \r\n\tIn chapter
    4 we apply models of record statistics and innovation to study cultural evolution
    in sport. We propose a model of sport evolution that combines deterministic improvements
    in performance and stochastic bursts of improvements due to innovation. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Simon
  full_name: Rella, Simon
  id: B4765ACA-AA38-11E9-AC9A-0930E6697425
  last_name: Rella
citation:
  ama: 'Rella S. Adaptive processes in biology and culture: Models of evolving vaccine
    resistance and the record statistics of innovation. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20811">10.15479/AT-ISTA-20811</a>'
  apa: 'Rella, S. (2025). <i>Adaptive processes in biology and culture: Models of
    evolving vaccine resistance and the record statistics of innovation</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20811">https://doi.org/10.15479/AT-ISTA-20811</a>'
  chicago: 'Rella, Simon. “Adaptive Processes in Biology and Culture: Models of Evolving
    Vaccine Resistance and the Record Statistics of Innovation.” Institute of Science
    and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20811">https://doi.org/10.15479/AT-ISTA-20811</a>.'
  ieee: 'S. Rella, “Adaptive processes in biology and culture: Models of evolving
    vaccine resistance and the record statistics of innovation,” Institute of Science
    and Technology Austria, 2025.'
  ista: 'Rella S. 2025. Adaptive processes in biology and culture: Models of evolving
    vaccine resistance and the record statistics of innovation. Institute of Science
    and Technology Austria.'
  mla: 'Rella, Simon. <i>Adaptive Processes in Biology and Culture: Models of Evolving
    Vaccine Resistance and the Record Statistics of Innovation</i>. Institute of Science
    and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20811">10.15479/AT-ISTA-20811</a>.'
  short: 'S. Rella, Adaptive Processes in Biology and Culture: Models of Evolving
    Vaccine Resistance and the Record Statistics of Innovation, Institute of Science
    and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-12-12T14:39:56Z
date_published: 2025-12-15T00:00:00Z
date_updated: 2026-07-29T12:57:49Z
day: '15'
ddc:
- '616'
- '576'
- '614'
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: GaTk
- _id: FyKo
doi: 10.15479/AT-ISTA-20811
doi_confirm: '1'
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  date_created: 2025-12-16T21:52:19Z
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language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '95'
publication_identifier:
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  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
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status: public
supervisor:
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
title: 'Adaptive processes in biology and culture: Models of evolving vaccine resistance
  and the record statistics of innovation'
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20276'
abstract:
- lang: eng
  text: "Complex 3D shapes can be created by morphing flat 2D configurations. Such
    deformations\r\neither preserve the intrinsic material geometry (e.g., folding
    paper) or modify it through\r\nlocalized contraction. Once transformed, the 3D
    shape can be further controlled to achieve a\r\ntarget functionality. A key challenge
    is to take the material specifications and the actuation\r\nprocess as input to
    automatically design the target 3D shape and its functionality. This thesis\r\npresents
    two novel computational pipelines for the design and control of shape-morphing\r\nstructures
    used to create functional prototypes.\r\nThe first pipeline borrows from the art
    of origami to fold paper into intricate shapes and\r\napplies this principle to
    make 3D lighting displays. We introduce, PCBend a computational\r\ndesign approach
    that covers a surface with individually addressable RGB LEDs, effectively\r\nforming
    a low-resolution surface by folding rigid printed circuit boards (PCBs). We optimize\r\ncut
    patterns on PCBs to act as hinges and co-design LED placement, circuit routing,
    and\r\nfabrication constraints to produce PCB blueprints. The PCBs are fabricated
    using automated\r\nstandard manufacturing services with LEDs embedded on them.
    Finally, the fabricated PCBs\r\nare cut along the contour and folded onto a 3D-printed
    support. The 3D lighting display is\r\nthen controlled to display complex surface
    light patterns.\r\nCreating 3D shapes through folding is only possible if their
    planar configuration, called ”unfolding” exists without any distortion or overlap.
    Existing methods often permit distortion\r\nor require multiple patches, which
    are unsuitable for fabrication pipelines that rely on folding\r\nnon-stretchable
    materials. We reinforce such fabrication pipelines by providing a geometric\r\nrelaxation
    to the problem, where the input shape is modified to admit overlap-free unfolding.\r\nThe
    second fabrication pipeline extends shape morphing to soft robotics by emulating
    nature’s\r\nblueprint of distributed actuation. Inspired by vertebrates, we build
    musculoskeletal robots\r\nusing modular active actuators, employing Liquid Crystal
    Elastomers (LCEs) as shrinkable\r\nartificial muscles integrated with 3D-printed
    bones. The chemical composition of LCEs is\r\naltered to enable untethered actuation
    through infrared radiation, allowing active control of\r\nindividual muscles and
    their corresponding bones. The combined motion of individual bones\r\ndefines
    the robot’s overall shape and functionality. Our proposed system significantly
    expands\r\nboth the design and control spaces of soft robots, which we harness
    using our computational\r\ndesign tools. We build several physical robots that
    exhibit complex shape morphing and varied\r\nterrain navigation, showcasing the
    versatility of our pipeline.\r\nThis thesis explores applications ranging from
    intricate light patterns displayed on 3D shapes\r\nformed by folding rigid PCBs
    to untethered robots that use contractile muscles to exhibit\r\nshape morphing
    and locomotion. Through these examples, the thesis highlights how computational
    design and distributed actuation, integrated with novel materials, can transform\r\npassive
    structures into functional prototypes."
acknowledgement: "Financial support was provided by the European Research Council
  (ERC) under grant agreement No 715767 - MATERIALIZABLE: Intelligent fabrication-oriented
  Computational Design\r\nand Modeling that I gratefully acknowledge.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Manas
  full_name: Bhargava, Manas
  id: FF8FA64C-AA6A-11E9-99AD-50D4E5697425
  last_name: Bhargava
  orcid: 0009-0007-6138-6890
citation:
  ama: 'Bhargava M. Design and control of deformable structures: From PCB lighting
    displays to elastomer robots. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20276">10.15479/AT-ISTA-20276</a>'
  apa: 'Bhargava, M. (2025). <i>Design and control of deformable structures: From
    PCB lighting displays to elastomer robots</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT-ISTA-20276">https://doi.org/10.15479/AT-ISTA-20276</a>'
  chicago: 'Bhargava, Manas. “Design and Control of Deformable Structures: From PCB
    Lighting Displays to Elastomer Robots.” Institute of Science and Technology Austria,
    2025. <a href="https://doi.org/10.15479/AT-ISTA-20276">https://doi.org/10.15479/AT-ISTA-20276</a>.'
  ieee: 'M. Bhargava, “Design and control of deformable structures: From PCB lighting
    displays to elastomer robots,” Institute of Science and Technology Austria, 2025.'
  ista: 'Bhargava M. 2025. Design and control of deformable structures: From PCB lighting
    displays to elastomer robots. Institute of Science and Technology Austria.'
  mla: 'Bhargava, Manas. <i>Design and Control of Deformable Structures: From PCB
    Lighting Displays to Elastomer Robots</i>. Institute of Science and Technology
    Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20276">10.15479/AT-ISTA-20276</a>.'
  short: 'M. Bhargava, Design and Control of Deformable Structures: From PCB Lighting
    Displays to Elastomer Robots, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-09-02T14:48:39Z
date_published: 2025-09-02T00:00:00Z
date_updated: 2026-07-29T13:03:31Z
day: '02'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: BeBi
doi: 10.15479/AT-ISTA-20276
doi_confirm: '1'
ec_funded: 1
file:
- access_level: open_access
  checksum: 5baf8ca46c86a94fc8380ff1007aabd4
  content_type: application/pdf
  creator: mbhargav
  date_created: 2025-09-03T10:40:52Z
  date_updated: 2025-09-03T10:40:52Z
  file_id: '20284'
  file_name: 2025-Bhargava-Manas-Thesis.pdf
  file_size: 161436245
  relation: main_file
  success: 1
- access_level: closed
  checksum: 66878fafbc0074f88ddd18f24a9fc647
  content_type: application/x-zip-compressed
  creator: mbhargav
  date_created: 2025-09-03T13:18:05Z
  date_updated: 2025-09-04T09:22:29Z
  file_id: '20285'
  file_name: manas_phd_thesis_source_files.zip
  file_size: 198831315
  relation: source_file
file_date_updated: 2025-09-04T09:22:29Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: '96'
project:
- _id: 24F9549A-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '715767'
  name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and
    Modeling'
publication_identifier:
  isbn:
  - 978-3-99078-065-7
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '13049'
    relation: part_of_dissertation
    status: public
  - id: '18565'
    relation: part_of_dissertation
    status: public
  - id: '20286'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Bernd
  full_name: Bickel, Bernd
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
title: 'Design and control of deformable structures: From PCB lighting displays to
  elastomer robots'
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20203'
abstract:
- lang: eng
  text: Tribocharging, or contact electrification, is the phenomenon in which two
    initially neutral materials exchange electric charge through contact and subsequent
    separation. While it is widely observed in everyday life and crucial to numerous
    natural processes, even the most basic aspects of tribocharging are still a mystery—what
    are the charge carriers involved and what drives their exchange? This work spans
    three separate projects that address different aspects of tribocharging. First,
    we introduce a novel strategy combining Finite Element Method (FEM) simulations
    with Kelvin Probe Force Microscopy (KPFM) to quantitatively extract surface charge
    density from surface voltage maps. Second, we present a simple theoretical model
    that allows for the existence of triboelectric cycles, under the assumption that
    multiple charge carrying species are involved. Third, we present experimental
    evidence that identical materials can spontaneously evolve into a triboelectric
    series, driven by contact history. Modeling this behavior enables the replication
    of experimental results with simulations, and even experimentally forcing the
    appearance of a pre-designed series by manipulating contact history. Together,
    the findings from these projects challenge traditional views on tribocharging,
    provide new tools for probing it, and open up new avenues of research—all with
    the hopes of bringing us closer to understanding this puzzling phenomenon.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: EM-Fac
- _id: LifeSc
- _id: ScienComp
acknowledgement: "The project in Chapter 2 has received funding from the European
  Research Council (ERC) under\r\nthe European Union’s Horizon 2020 research and innovation
  programme (Grant Agreement\r\nNo. 949120).\r\nThe project in Chapter 3 has received
  funding from the European Research Council (ERC) under\r\nthe European Union’s Horizon
  2020 research and innovation programme (Grant Agreement\r\nNo. 949120).\r\nThe project
  in Chapter 4 has received financing from the European Research Council grant\r\nagreement
  No. 949120 under the European Union’s Horizon 2020 research and innovation\r\nprogramme.
  The Analytical Instrumentation Center of the TU Wien acknowledges support by\r\nthe
  FFG project ‘ELSA’ under grant no. 884672. C.M.P. and M.O. acknowledge the state\r\nof
  Lower Austria and the European Regional Development Fund under grant no. WST3-F542638/004-2021.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Juan Carlos A
  full_name: Sobarzo Ponce, Juan Carlos A
  id: 4B807D68-AE37-11E9-AC72-31CAE5697425
  last_name: Sobarzo Ponce
citation:
  ama: 'Sobarzo Ponce JCA. Tribocharging of identical insulators: Triboelectric series,
    triboelectric cycles and surface charges. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20203">10.15479/AT-ISTA-20203</a>'
  apa: 'Sobarzo Ponce, J. C. A. (2025). <i>Tribocharging of identical insulators:
    Triboelectric series, triboelectric cycles and surface charges</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20203">https://doi.org/10.15479/AT-ISTA-20203</a>'
  chicago: 'Sobarzo Ponce, Juan Carlos A. “Tribocharging of Identical Insulators:
    Triboelectric Series, Triboelectric Cycles and Surface Charges.” Institute of
    Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20203">https://doi.org/10.15479/AT-ISTA-20203</a>.'
  ieee: 'J. C. A. Sobarzo Ponce, “Tribocharging of identical insulators: Triboelectric
    series, triboelectric cycles and surface charges,” Institute of Science and Technology
    Austria, 2025.'
  ista: 'Sobarzo Ponce JCA. 2025. Tribocharging of identical insulators: Triboelectric
    series, triboelectric cycles and surface charges. Institute of Science and Technology
    Austria.'
  mla: 'Sobarzo Ponce, Juan Carlos A. <i>Tribocharging of Identical Insulators: Triboelectric
    Series, Triboelectric Cycles and Surface Charges</i>. Institute of Science and
    Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20203">10.15479/AT-ISTA-20203</a>.'
  short: 'J.C.A. Sobarzo Ponce, Tribocharging of Identical Insulators: Triboelectric
    Series, Triboelectric Cycles and Surface Charges, Institute of Science and Technology
    Austria, 2025.'
corr_author: '1'
date_created: 2025-08-21T11:42:59Z
date_published: 2025-08-27T00:00:00Z
date_updated: 2026-07-29T13:11:25Z
day: '27'
ddc:
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ScWa
doi: 10.15479/AT-ISTA-20203
doi_confirm: '1'
ec_funded: 1
file:
- access_level: open_access
  checksum: 661b9d3786cfc985be811befc3262bf5
  content_type: application/pdf
  creator: jsobarzo
  date_created: 2025-08-27T14:50:32Z
  date_updated: 2025-08-27T14:50:32Z
  file_id: '20237'
  file_name: 2025_Sobarzo_JuanCarlos_Thesis.pdf
  file_size: 12667200
  relation: main_file
  success: 1
- access_level: closed
  checksum: ca2f24e6c3b55912982521707552a0f5
  content_type: application/x-zip-compressed
  creator: jsobarzo
  date_created: 2025-08-27T14:50:32Z
  date_updated: 2025-08-28T08:19:07Z
  file_id: '20238'
  file_name: 2025_Sobarzo_JuanCarlos_Thesis.zip
  file_size: 18940521
  relation: source_file
file_date_updated: 2025-08-28T08:19:07Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '96'
project:
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
  call_identifier: H2020
  grant_number: '949120'
  name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
publication_identifier:
  isbn:
  - 978-3-99078-062-6
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '12109'
    relation: part_of_dissertation
    status: public
  - id: '15322'
    relation: part_of_dissertation
    status: public
  - id: '19278'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
title: 'Tribocharging of identical insulators: Triboelectric series, triboelectric
  cycles and surface charges'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20371'
abstract:
- lang: eng
  text: "Quantum mechanics reveals a world that defies classical determinism, where
    uncertainty, superposition, and fluctuations are fundamental aspects. Engineering
    devices that harness these quantum features requires not only precision, but also
    a deep understanding of how they interact with their surrounding environment.
    Superconducting circuits, which exploit\r\nmacroscopic quantum coherence in low-loss
    superconducting materials, provide a scalable platform for implementing such systems.
    Among the critical elements in these circuits, superinductors—high-impedance,
    dissipation-free inductive components—play a central role by suppressing charge
    fluctuations. They allow quantum states to be delocalized in phase space, protect
    qubits from environmental noise, and facilitate access to phenomena such as dual
    Josephson physics and ultra-strong coupling regimes. \r\nThis thesis explores
    two complementary implementations of high-impedance circuits: geometric superinductors,
    demonstrating that high impedance can be achieved beyond kinetic inductance,\r\nand
    Josephson junction chains, used to investigate both microwave mode properties
    and DC transport across the superconductor-to-insulator transition. \r\nPart I
    addresses geometric superinductors. Contrary to the common belief that high-impedance
    superconducting circuits require kinetic inductance, we demonstrate that purely
    geometric designs can achieve characteristic impedance exceeding the resistance
    quantum. By exploiting mutual coupling between adjacent turns, coil-based inductors
    achieve enhanced self-inductance, creating a reliable platform for qubits and
    resonators. Modeling, simulation, fabrication, and\r\ncharacterization confirm
    that these elements behave as superinductor. With low loss, high linearity, and
    minimal stray capacitance, these elements are reproducible, free of uncontrolled
    tunneling events, and capable of strong magnetic coupling. This establishes geometric
    superinductors as robust, single-wave-function superconducting devices suitable
    for hardware protected qubits and hybrid systems.\r\nPart II presents classical
    numerical simulations of a Quantum Phase Slip circuit to study dual Shapiro steps.
    The circuit consists of an ideal Quantum Phase Slip element embedded in a resistive-inductive
    environment with a parasitic capacitance.\r\nPart III extends the investigation
    of high characteristic-impedance circuit elements to one-dimensional Josephson
    junction chains, which act as a quantum simulator for many-body physics and the
    superconductor–insulator transition. Different devices are realized on both sides
    of the DC phase transition, showing either a supercurrent branch or Coulomb blockade
    at zero bias. The effect of the crossover on microwave modes, however, remains
    insufficiently investigated. Studying these modes provides insight into the interplay
    between disorder and phase-slip events. Small differences in circuit component
    sizes determine which side of the transition a device falls on, making these results
    relevant not only for fundamental understanding but also for the design of quantum
    devices, emphasizing the crucial role of the\r\nelectromagnetic environment in
    stabilizing and controlling fragile quantum states. \r\nTogether, these results
    illustrate how carefully engineered high characteristic-impedance elements provide
    a link between macroscopic circuits and the inherently uncertain quantum world,
    enabling experiments that probe, control, and ultimately exploit quantum fluctuations
    for applications in quantum information, metrology, solid state physics and beyond.\r\n\r\n"
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
acknowledgement: "I also gratefully acknowledge the generous support of the NOMIS
  Foundation Project \"Protected\r\nStates of Quantum Matter\" and the grant from
  the Beyond-C consortium. Their funding\r\nmade this research possible and gave me
  the freedom to ask ambitious questions, and try to\r\nanswer them.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Andrea
  full_name: Trioni, Andrea
  id: 42F71B44-F248-11E8-B48F-1D18A9856A87
  last_name: Trioni
citation:
  ama: 'Trioni A. High-impedance quantum circuits for mesoscopic physics: Geometric
    superinductors and insulating Josephson Chains. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20371">10.15479/AT-ISTA-20371</a>'
  apa: 'Trioni, A. (2025). <i>High-impedance quantum circuits for mesoscopic physics:
    Geometric superinductors and insulating Josephson Chains</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20371">https://doi.org/10.15479/AT-ISTA-20371</a>'
  chicago: 'Trioni, Andrea. “High-Impedance Quantum Circuits for Mesoscopic Physics:
    Geometric Superinductors and Insulating Josephson Chains.” Institute of Science
    and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20371">https://doi.org/10.15479/AT-ISTA-20371</a>.'
  ieee: 'A. Trioni, “High-impedance quantum circuits for mesoscopic physics: Geometric
    superinductors and insulating Josephson Chains,” Institute of Science and Technology
    Austria, 2025.'
  ista: 'Trioni A. 2025. High-impedance quantum circuits for mesoscopic physics: Geometric
    superinductors and insulating Josephson Chains. Institute of Science and Technology
    Austria.'
  mla: 'Trioni, Andrea. <i>High-Impedance Quantum Circuits for Mesoscopic Physics:
    Geometric Superinductors and Insulating Josephson Chains</i>. Institute of Science
    and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20371">10.15479/AT-ISTA-20371</a>.'
  short: 'A. Trioni, High-Impedance Quantum Circuits for Mesoscopic Physics: Geometric
    Superinductors and Insulating Josephson Chains, Institute of Science and Technology
    Austria, 2025.'
corr_author: '1'
date_created: 2025-09-23T09:57:57Z
date_published: 2025-09-23T00:00:00Z
date_updated: 2026-07-29T13:12:10Z
day: '23'
ddc:
- '539'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JoFi
doi: 10.15479/AT-ISTA-20371
doi_confirm: '1'
ec_funded: 1
file:
- access_level: open_access
  checksum: 6fb925648dfa5f4384814c552ee2f099
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  creator: atrioni
  date_created: 2025-09-25T07:15:05Z
  date_updated: 2025-09-25T14:25:31Z
  file_id: '20392'
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  checksum: 619dc614bdfbf3999b76ac8890b2cebd
  content_type: application/x-zip-compressed
  creator: atrioni
  date_created: 2025-09-25T14:45:43Z
  date_updated: 2025-09-26T07:20:48Z
  file_id: '20396'
  file_name: 2025_Trioni_Andrea_Thesis.zip
  file_size: 60079009
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file_date_updated: 2025-09-26T07:20:48Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '202'
project:
- _id: eb9b30ac-77a9-11ec-83b8-871f581d53d2
  name: Protected states of quantum matter
- _id: bdb108fd-d553-11ed-ba76-83dc74a9864f
  grant_number: F07105
  name: QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration
    of Superconducting Quantum Circuits
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication_identifier:
  isbn:
  - 978-3-99078-067-1
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '8755'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
title: 'High-impedance quantum circuits for mesoscopic physics: Geometric superinductors
  and insulating Josephson Chains'
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20339'
abstract:
- lang: eng
  text: "This thesis investigates the interplay between algebraic and topological
    methods and combinatorial problems, focusing on approximate graph colourings and
    mass partitioning. The unifying theme throughout the dissertation is the use of
    continuous maps and symmetry constraints to extract combinatorial insights.\r\n\r\nWe
    first explore approximate graph colouring problems and more generally promise
    constraint satisfaction problems. Using tools from equivariant topology in combination
    with the general theory of polymorphism of a promise constraint satisfaction problem,
    we establish hardness for specific types of approximations.\r\n\r\nIn the second
    part, we address mass partitioning problems, where one seeks to divide geometric
    objects or measures in Euclidean space into parts of equal size using hyperplanes.
    Employing techniques from topological combinatorics (configuration space/test
    map setup and Borsuk–Ulam type theorems), we both obtain a new equipartitioning
    result in the and provide a fast algorithm for computing equipartitioning of point
    sets in 3D.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Gianluca
  full_name: Tasinato, Gianluca
  id: 0433290C-AF8F-11E9-A4C7-F729E6697425
  last_name: Tasinato
citation:
  ama: 'Tasinato G. Topological methods in discrete geometry and theoretical computer
    science: Measure partitioning and constraint satisfaction problems. 2025. doi:<a
    href="https://doi.org/10.15479/AT-ISTA-20339">10.15479/AT-ISTA-20339</a>'
  apa: 'Tasinato, G. (2025). <i>Topological methods in discrete geometry and theoretical
    computer science: Measure partitioning and constraint satisfaction problems</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20339">https://doi.org/10.15479/AT-ISTA-20339</a>'
  chicago: 'Tasinato, Gianluca. “Topological Methods in Discrete Geometry and Theoretical
    Computer Science: Measure Partitioning and Constraint Satisfaction Problems.”
    Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20339">https://doi.org/10.15479/AT-ISTA-20339</a>.'
  ieee: 'G. Tasinato, “Topological methods in discrete geometry and theoretical computer
    science: Measure partitioning and constraint satisfaction problems,” Institute
    of Science and Technology Austria, 2025.'
  ista: 'Tasinato G. 2025. Topological methods in discrete geometry and theoretical
    computer science: Measure partitioning and constraint satisfaction problems. Institute
    of Science and Technology Austria.'
  mla: 'Tasinato, Gianluca. <i>Topological Methods in Discrete Geometry and Theoretical
    Computer Science: Measure Partitioning and Constraint Satisfaction Problems</i>.
    Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20339">10.15479/AT-ISTA-20339</a>.'
  short: 'G. Tasinato, Topological Methods in Discrete Geometry and Theoretical Computer
    Science: Measure Partitioning and Constraint Satisfaction Problems, Institute
    of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-09-10T12:17:55Z
date_published: 2025-09-10T00:00:00Z
date_updated: 2026-07-29T13:13:18Z
day: '10'
ddc:
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degree_awarded: PhD
department:
- _id: GradSch
- _id: UlWa
doi: 10.15479/AT-ISTA-20339
doi_confirm: '1'
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  issn:
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supervisor:
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
title: 'Topological methods in discrete geometry and theoretical computer science:
  Measure partitioning and constraint satisfaction problems'
tmp:
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...
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abstract:
- lang: eng
  text: "Game Theory is the mathematical formalization of social dynamics - systems
    where agents interact over time and the evolution of the state of the system depends
    on the decisions of every player. \r\nThis thesis takes the perspective of a single
    player and focuses on what they can guarantee in the worst case over the behavior
    of other players.\r\nIn other words, we consider that the objective of every other
    player in the game is exactly the opposite to the player.\r\nWe focus on sustained
    interactions over time, where the players repeatedly obtain quantitative rewards
    over time, and they are interested in maximizing their long-term performance.\t\r\nFormally,
    this thesis focuses on zero-sum games with the liminf average objective.\r\nTwo
    fundamental questions that Game Theory aims to answer are the following.\r\n\r\n1.
    How much can a player guarantee to obtain after the interaction?\r\n\r\n2. How
    to act in order to obtain the previously mentioned guarantee?\r\n\r\nThese questions
    are formalized by the concepts of \"value\" and \"optimal strategies\". \t\r\nWe
    study their properties on games that exhibit one or more of the following properties.
    \r\n\r\n1. Partial Observation: \r\nthe players can not perfectly observe the
    current state of the system during the game. We consider the model of (finite)
    Partially Observable Markov Decision Processes and prove that finite-memory strategies
    are sufficient to approximately guarantee the value.\r\n\r\n2. Perturbed Description:
    \r\nthe formal description of the game is perturbed by a small parameter.\r\nWe
    consider the model of (finite) Perturbed Matrix Games, and provide algorithms
    to check various robustness properties and to compute the parameterized value
    and optimal strategies.\r\n\r\n3. Stochastic Transitions: \r\nthe actions of the
    players determine the behavior of the evolution of the system, described as a
    probability distribution over the next state.\r\nWe consider the model of (finite)
    Perturbed Stochastic Games and provide formulas for the marginal value.\r\n\r\n4.
    Infinite States: \r\nthe system can be in infinitely many states.\r\nWe consider
    the model of Random Dynamic Games on a class of infinite graphs, prove the existence
    of the value, and quantify the concentration of finite-horizon values."
acknowledgement: "Funding sources The works included in this thesis were partially
  supported by:\r\n• Austrian Science Fund (FWF), grants 10.55776/COE12 and No RiSE/SHiNE
  S11407,\r\n• French Agence Nationale de la Recherche (ANR), grants ANR-21-CE40-0020
  (CONVERGENCE) and ANR-20-CE40-0002 (GrHyDy),\r\n• Fondation Mathématique Jaques
  Hadamard, grant PGMO RSG 2018-0031H,\r\n• European Research Council (ERC), Consolidator
  grant 863818 (ForM-SMArt),\r\n• Agencia Nacional de Investigación y Desarrollo (ANID
  Chile), grant ACT210005,\r\n• Fondo Nacional de Desarrollo Científico y Tecnológico
  (Fondecyt Chile), grant 1220174,\r\n• Comisión Nacional de Investigación Científica
  y Tecnológica (CONICYT Chile), grant\r\nPII 20150140,\r\n• Evaluation-orientation
  de la Coopération Scientifique and Comisión Nacional de Investigación Científica
  y Tecnológica (ECOS-CONICYT), grant C15E03,\r\n• European Cooperation in Science
  and Technology (E-COST), grants CA16228 - European\r\nNetwork for Game Theory (GAMENET)
  and E-COST-GRANT-CA16228-c5a69859.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Raimundo J
  full_name: Saona Urmeneta, Raimundo J
  id: BD1DF4C4-D767-11E9-B658-BC13E6697425
  last_name: Saona Urmeneta
  orcid: 0000-0001-5103-038X
citation:
  ama: 'Saona Urmeneta RJ. Robustness of solutions in game theory: Values and strategies
    in partially observable, perturbed, stochastic, and infinite games. 2025. doi:<a
    href="https://doi.org/10.15479/AT-ISTA-20234">10.15479/AT-ISTA-20234</a>'
  apa: 'Saona Urmeneta, R. J. (2025). <i>Robustness of solutions in game theory: Values
    and strategies in partially observable, perturbed, stochastic, and infinite games</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20234">https://doi.org/10.15479/AT-ISTA-20234</a>'
  chicago: 'Saona Urmeneta, Raimundo J. “Robustness of Solutions in Game Theory: Values
    and Strategies in Partially Observable, Perturbed, Stochastic, and Infinite Games.”
    Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20234">https://doi.org/10.15479/AT-ISTA-20234</a>.'
  ieee: 'R. J. Saona Urmeneta, “Robustness of solutions in game theory: Values and
    strategies in partially observable, perturbed, stochastic, and infinite games,”
    Institute of Science and Technology Austria, 2025.'
  ista: 'Saona Urmeneta RJ. 2025. Robustness of solutions in game theory: Values and
    strategies in partially observable, perturbed, stochastic, and infinite games.
    Institute of Science and Technology Austria.'
  mla: 'Saona Urmeneta, Raimundo J. <i>Robustness of Solutions in Game Theory: Values
    and Strategies in Partially Observable, Perturbed, Stochastic, and Infinite Games</i>.
    Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20234">10.15479/AT-ISTA-20234</a>.'
  short: 'R.J. Saona Urmeneta, Robustness of Solutions in Game Theory: Values and
    Strategies in Partially Observable, Perturbed, Stochastic, and Infinite Games,
    Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-08-27T14:00:13Z
date_published: 2025-08-27T00:00:00Z
date_updated: 2026-07-29T13:14:37Z
day: '27'
ddc:
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrCh
doi: 10.15479/AT-ISTA-20234
doi_confirm: '1'
ec_funded: 1
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project:
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  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
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  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
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supervisor:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
title: 'Robustness of solutions in game theory: Values and strategies in partially
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type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
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...
---
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abstract:
- lang: eng
  text: "This thesis deals with several different models for complex quantum mechanical
    systems and is structured in three main parts. \r\n\t\r\nIn Part I, we study mean
    field random matrices as models for quantum Hamiltonians. Our focus lies on proving
    concentration estimates for resolvents of random matrices, so-called local laws,
    mostly in the setting of multiple resolvents. These estimates have profound consequences
    for eigenvector overlaps and thermalization problems. More concretely, we obtain,
    e.g., the optimal eigenstate thermalization hypothesis (ETH) uniformly in the
    spectrum for Wigner matrices, an optimal lower bound on non-Hermitian eigenvector
    overlaps, and prethermalization for deformed Wigner matrices.\tIn order to prove
    our novel multi-resolvent local laws, we develop and devise two main methods,
    the static Psi-method and the dynamical Zigzag strategy. \r\n\t\r\nIn Part II,
    we study Bardeen-Cooper-Schrieffer (BCS) theory, the standard mean field microscopic
    theory of superconductivity. We focus on asymptotic formulas for the characteristic
    critical temperature and energy gap of a superconductor and prove universality
    of their ratio in various physical regimes. Additionally, we investigate multi-band
    superconductors and show that inter-band coupling effects can only enhance the
    critical temperature. \r\n\t\r\nIn Part III, we study quantum lattice systems.
    On the one hand, we show a strong version of the local-perturbations-perturb-locally
    (LPPL) principle for the ground state of weakly interacting quantum spin systems
    with a uniform on-site gap. On the other hand, we introduce a notion of a local
    gap and rigorously justify response theory and the Kubo formula under the weakened
    assumption of a local gap. \r\n\t\r\nAdditionally, we discuss two classes of problems
    which do not fit into the three main parts of the thesis. These are deformational
    rigidity of Liouville metrics on the torus and relativistic toy models of particle
    creation via interior-boundary-conditions (IBCs).  "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
citation:
  ama: 'Henheik SJ. Modeling complex quantum systems: Random matrices, BCS theory,
    and quantum lattice systems. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19540">10.15479/AT-ISTA-19540</a>'
  apa: 'Henheik, S. J. (2025). <i>Modeling complex quantum systems: Random matrices,
    BCS theory, and quantum lattice systems</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT-ISTA-19540">https://doi.org/10.15479/AT-ISTA-19540</a>'
  chicago: 'Henheik, Sven Joscha. “Modeling Complex Quantum Systems: Random Matrices,
    BCS Theory, and Quantum Lattice Systems.” Institute of Science and Technology
    Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-19540">https://doi.org/10.15479/AT-ISTA-19540</a>.'
  ieee: 'S. J. Henheik, “Modeling complex quantum systems: Random matrices, BCS theory,
    and quantum lattice systems,” Institute of Science and Technology Austria, 2025.'
  ista: 'Henheik SJ. 2025. Modeling complex quantum systems: Random matrices, BCS
    theory, and quantum lattice systems. Institute of Science and Technology Austria.'
  mla: 'Henheik, Sven Joscha. <i>Modeling Complex Quantum Systems: Random Matrices,
    BCS Theory, and Quantum Lattice Systems</i>. Institute of Science and Technology
    Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19540">10.15479/AT-ISTA-19540</a>.'
  short: 'S.J. Henheik, Modeling Complex Quantum Systems: Random Matrices, BCS Theory,
    and Quantum Lattice Systems, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-04-10T21:21:18Z
date_published: 2025-04-10T00:00:00Z
date_updated: 2026-07-29T13:18:17Z
day: '10'
ddc:
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: LaEr
doi: 10.15479/AT-ISTA-19540
doi_confirm: '1'
ec_funded: 1
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- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '720'
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication_identifier:
  isbn:
  - 978-3-99078-057-2
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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status: public
supervisor:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
title: 'Modeling complex quantum systems: Random matrices, BCS theory, and quantum
  lattice systems'
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type: dissertation
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---
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acknowledged_ssus:
- _id: ScienComp
- _id: E-Lib
acknowledgement: "I would also like to acknowledge the Austrian Academy of Sciences
  for funding through the\r\nDOC Fellowship program (fellowship number 26917), the
  Grants Office at ISTA for their\r\nassistance with the application, and the Scientific
  Computing Unit for their support regarding\r\nhigh-performance computation.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Natalia
  full_name: Ruzickova, Natalia
  id: D2761128-D73D-11E9-A1BF-BA0DE6697425
  last_name: Ruzickova
citation:
  ama: Ruzickova N. Effect propagation in biological networks. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20357">10.15479/AT-ISTA-20357</a>
  apa: Ruzickova, N. (2025). <i>Effect propagation in biological networks</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20357">https://doi.org/10.15479/AT-ISTA-20357</a>
  chicago: Ruzickova, Natalia. “Effect Propagation in Biological Networks.” Institute
    of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20357">https://doi.org/10.15479/AT-ISTA-20357</a>.
  ieee: N. Ruzickova, “Effect propagation in biological networks,” Institute of Science
    and Technology Austria, 2025.
  ista: Ruzickova N. 2025. Effect propagation in biological networks. Institute of
    Science and Technology Austria.
  mla: Ruzickova, Natalia. <i>Effect Propagation in Biological Networks</i>. Institute
    of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20357">10.15479/AT-ISTA-20357</a>.
  short: N. Ruzickova, Effect Propagation in Biological Networks, Institute of Science
    and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-09-15T17:04:48Z
date_published: 2025-09-15T00:00:00Z
date_updated: 2026-08-10T07:47:56Z
day: '15'
ddc:
- '570'
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: GaTk
doi: 10.15479/AT-ISTA-20357
doi_confirm: '1'
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has_accepted_license: '1'
keyword:
- gene regulation
- networks
- omnigenic model
- pancreas
- collective behaviour
language:
- iso: eng
month: '09'
oa_version: Published Version
page: '156'
project:
- _id: 7bec9174-9f16-11ee-852c-ded9fe5f810e
  name: Collective behaviour of cells in pancreatic Islets of Langerhans
publication_identifier:
  isbn:
  - 978-3-99078-066-4
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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  - id: '18525'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
title: Effect propagation in biological networks
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20074'
abstract:
- lang: eng
  text: "Prenatal immune challenges pose significant risks to human embryonic brain
    and eye development. However, we still lack knowledge about the safe usage of
    anti-inflammatory drugs during pregnancy. Human induced pluripotent stem cell
    (hIPSC)-derived brain organoid models provide a unique opportunity to investigate
    neuronal development and have started to explore functional consequences upon
    viral infection. However, brain organoids usually lack microglia, the brain-resident
    immune cells. They are present in the early human embryonic brain and actively
    participate in neuronal circuit development. At the same time, microglia are known
    for their immune-sensing properties and will influence viral-mediated effects.
    In my thesis, I was interested to study the multifunctional role of human microglia
    during retinal development. \r\nIn chapter 1, I characterize the innate occurrence
    of IBA1+-microglia-like cells within the retinal organoid differentiation (Bartalska
    et al., 2022). Therefore, we differentiate hIPSC using an unguided retinal organoid
    differentiation protocol and observe the presence of IBA1+-microglia-like cells
    alongside retinal cups between week 3 and 4 in 2.5D culture. However, instead
    of infiltrating the neuroectodermal sides, they enrich within non-pigmented, 3D-cystic
    compartments that develop in low numbers parallel to 3D-retinal organoids. To
    enrich for IBA1+-microglia precursors (preMG), we guided the differentiation with
    a low-dosed BMP4 application, which prevents retinal cup development and enhances
    microglia and 3D-cysts formation. We characterize the differentiated preMG for
    their microglia-like identity and validated their functionality. In parallel,
    mass spectrometry identifies the 3D-cysts to express mesenchymal and epithelial
    markers. We confirm that comparable 3D-cysts are also the preferential environment
    for IBA1+-microglia-like cells within the unguided retinal organoid differentiation.
    \r\nIn chapter 2, I investigate how microglia influence retinal development and
    whether they contribute to viral-mediated consequences (Schmied et al., 2025).
    Here, we assemble preMG, which we have characterized in chapter 1, into 3D-retinal
    organoids. Once the outer plexiform layer forms, microglia-like cells (iMG) populate
    them and interact with retinal cell types. However, at this developmental stage,
    the ganglion cell number decreases in 3D-retinal organoids. Thus, we adapted the
    model into 2D which promotes their survival. Integrated iMG engulf ganglion cells
    and control their cell number. In parallel, we apply the immunostimulant POLY(I:C)
    to mimic a fetal viral infection. Although POLY(I:C) stimulation affects iMG phenotype,
    it does not influence their interaction with ganglion cells. Furthermore, iMG
    presence significantly contributes to the supernatant’s inflammatory secretome
    and increases retinal cell proliferation. Simultaneous exposure to the non-steroidal
    anti-inflammatory drug (NSAID) ibuprofen dampens POLY(I:C)-mediated consequences
    of the iMG phenotype and ameliorates cell proliferation. Remarkably, while POLY(I:C)
    disrupts neuronal calcium dynamics independent of iMG presence, ibuprofen rescues
    this effect only in the presence of iMG. Mechanistically, ibuprofen blocks the
    enzymes cyclooxygenase 1 and 2 (COX1/ PTGS1 and COX2/ PTGS2) simultaneously, from
    which iMG predominantly express COX1. Selective inhibition of COX1 does not restore
    the calcium peak amplitude upon POLY(I:C) stimulation, indicating ibuprofen’s
    effect depends on the presence and interplay of both, COX1 and COX2. \r\nIn summary,
    we characterized the 3D-retinal organoid model for the occurrence of IBA1+-microglia
    like cells. As the innately developing IBA1+-cells enrich in mesenchymal over
    retinal structures, we optimized a protocol to differentiate IBA1+-microglia precursors.
    By combining these two models we generate microglia-assembled retinal organoids.
    Our results underscore the importance of microglia during neurodevelopment, in
    the context of prenatal immune challenges and provide insight into the mechanisms
    by which ibuprofen exerts its protective effects during embryonic development."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Verena
  full_name: Hübschmann, Verena
  id: 32B7C918-F248-11E8-B48F-1D18A9856A87
  last_name: Hübschmann
citation:
  ama: Schmied V. Human microglia impact neuronal development in retinal organoids.
    2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20074">10.15479/AT-ISTA-20074</a>
  apa: Schmied, V. (2025). <i>Human microglia impact neuronal development in retinal
    organoids</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20074">https://doi.org/10.15479/AT-ISTA-20074</a>
  chicago: Schmied, Verena. “Human Microglia Impact Neuronal Development in Retinal
    Organoids.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20074">https://doi.org/10.15479/AT-ISTA-20074</a>.
  ieee: V. Schmied, “Human microglia impact neuronal development in retinal organoids,”
    Institute of Science and Technology Austria, 2025.
  ista: Schmied V. 2025. Human microglia impact neuronal development in retinal organoids.
    Institute of Science and Technology Austria.
  mla: Schmied, Verena. <i>Human Microglia Impact Neuronal Development in Retinal
    Organoids</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20074">10.15479/AT-ISTA-20074</a>.
  short: V. Schmied, Human Microglia Impact Neuronal Development in Retinal Organoids,
    Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-07-24T12:37:22Z
date_published: 2025-07-24T00:00:00Z
date_updated: 2026-08-12T08:45:16Z
day: '24'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: SaSi
doi: 10.15479/AT-ISTA-20074
doi_confirm: '1'
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language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '151'
project:
- _id: 9B99D380-BA93-11EA-9121-9846C619BF3A
  grant_number: SC19-017
  name: How human microglia shape developing neurons during health and inflammation
publication_identifier:
  isbn:
  - 978-3-99078-060-2
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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  - id: '11478'
    relation: part_of_dissertation
    status: public
  - id: '19593'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Sandra
  full_name: Siegert, Sandra
  id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
  last_name: Siegert
  orcid: 0000-0001-8635-0877
title: Human microglia impact neuronal development in retinal organoids
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
_id: '20147'
abstract:
- lang: eng
  text: "Quantitative properties offer a framework for specifying and verifying system
    behaviors beyond the traditional boolean perspective. For example, while a boolean
    property may specify whether a server eventually grants every request it receives,
    a quantitative one may map each server execution to its average response time.
    This quantitative view is relatively well-studied in the context of static verification.
    However, although such properties often appear in practice as performance or robustness
    measures in a dynamic verification context, a general theoretical framework for
    their analysis and classification from a monitoring perspective is still missing.\r\n\r\nIn
    this thesis, we aim to develop such a framework that takes resource-precision
    tradeoffs of monitors as a central consideration. We present the first theory
    of monitorability for quantitative properties where monitors can be naturally
    approximate and compared regarding their precision and resource use. In particular,
    we show that additional monitor resources such as registers or states lead to
    strictly better approximations for some properties. To enable such analyses in
    a machine-model independent way, we describe an abstract notion of monitors that
    can be instantiated with concrete models of monitors. Within this framework, we
    study how abstract monitors behave and identify classes of properties amenable
    to approximate monitoring with resource-precision considerations. We then extend
    the boolean safety-liveness dichotomy and safety-progress hierarchy to the quantitative
    setting with a monitoring perspective. In particular, we prove that every property
    is the pointwise minimum of a safety property and a liveness property, and properties
    that are both safe and co-safe can be approximately monitored arbitrarily precisely
    using only finitely many states. We also study the classes of quantitative properties
    definable by finite-state quantitative automata and provide algorithms for deciding
    their safety or liveness as well as their safety-liveness decompositions. Finally,
    we present the first general-purpose tool for automating the analysis, verification,
    and monitoring of quantitative automata.\r\n\r\n\r\n"
acknowledgement: "This work was supported in part by the Austrian Science Fund (FWF)\r\nunder
  grant Z211-N23 (Wittgenstein Award) and the ERC-2020-AdG 101020093.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Naci E
  full_name: Sarac, Naci E
  id: 8C6B42F8-C8E6-11E9-A03A-F2DCE5697425
  last_name: Sarac
citation:
  ama: Sarac NE. A monitoring-oriented theory and classification of quantitative specifications.
    2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20147">10.15479/AT-ISTA-20147</a>
  apa: Sarac, N. E. (2025). <i>A monitoring-oriented theory and classification of
    quantitative specifications</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-20147">https://doi.org/10.15479/AT-ISTA-20147</a>
  chicago: Sarac, Naci E. “A Monitoring-Oriented Theory and Classification of Quantitative
    Specifications.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20147">https://doi.org/10.15479/AT-ISTA-20147</a>.
  ieee: N. E. Sarac, “A monitoring-oriented theory and classification of quantitative
    specifications,” Institute of Science and Technology Austria, 2025.
  ista: Sarac NE. 2025. A monitoring-oriented theory and classification of quantitative
    specifications. Institute of Science and Technology Austria.
  mla: Sarac, Naci E. <i>A Monitoring-Oriented Theory and Classification of Quantitative
    Specifications</i>. Institute of Science and Technology Austria, 2025, doi:<a
    href="https://doi.org/10.15479/AT-ISTA-20147">10.15479/AT-ISTA-20147</a>.
  short: N.E. Sarac, A Monitoring-Oriented Theory and Classification of Quantitative
    Specifications, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-07T15:57:57Z
date_published: 2025-08-07T00:00:00Z
date_updated: 2026-08-12T08:46:04Z
day: '07'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ToHe
doi: 10.15479/AT-ISTA-20147
doi_confirm: '1'
ec_funded: 1
file:
- access_level: closed
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  date_updated: 2025-09-10T08:19:51Z
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  file_name: 2025_Sarac_NaciEge_Thesis.zip
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file_date_updated: 2025-09-10T08:19:51Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '149'
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: Formal methods for the design and analysis of complex systems
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publisher_comment: "In reference to IEEE copyrighted material which is used with permission
  in this thesis, the IEEE does not\r\nendorse any of ISTA's products or services.
  Internal or personal use of this\r\nmaterial is permitted. If interested in reprinting/republishing
  IEEE copyrighted material for advertising or promotional\r\npurposes or for creating
  new collective works for resale or redistribution, please go to\r\nhttp://www.ieee.org/publications_standards/publications/rights/rights_link.html
  to learn how to obtain a License from\r\nRightsLink.  If applicable, University
  Microfilms and/or ProQuest Library, or the Archives of Canada may supply single
  copies of the dissertation."
related_material:
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  - id: '11775'
    relation: part_of_dissertation
    status: public
  - id: '13140'
    relation: part_of_dissertation
    status: deleted
  - id: '19741'
    relation: part_of_dissertation
    status: public
  - id: '19643'
    relation: part_of_dissertation
    status: deleted
  - id: '17634'
    relation: part_of_dissertation
    status: public
  - id: '13221'
    relation: part_of_dissertation
    status: public
  - id: '9356'
    relation: part_of_dissertation
    status: public
  - id: '20342'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
title: A monitoring-oriented theory and classification of quantitative specifications
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20167'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "This work was supported by EMBO (ALTF 302-2019 to Niko Amin-Wetzel),
  the FWF\r\n(ESPRIT PR1054E140 to Niko Amin-Wetzel), the European Research Council\r\n(Advanced
  Grant 269058 to Mario de Bono) and Wellcome (209504/A/17/Z\r\nInvestigator Award
  to Mario de Bono). "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Hanna
  full_name: Schön, Hanna
  id: C8E17EDC-D7AA-11E9-B7B7-45ECE5697425
  last_name: Schön
citation:
  ama: Schön H. The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding
    GPCRs. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20167">10.15479/AT-ISTA-20167</a>
  apa: Schön, H. (2025). <i>The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs
    encoding GPCRs</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20167">https://doi.org/10.15479/AT-ISTA-20167</a>
  chicago: Schön, Hanna. “The ER Complex SUTU-7/MACO-1 Regulates the Fate of MRNAs
    Encoding GPCRs.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20167">https://doi.org/10.15479/AT-ISTA-20167</a>.
  ieee: H. Schön, “The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding
    GPCRs,” Institute of Science and Technology Austria, 2025.
  ista: Schön H. 2025. The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding
    GPCRs. Institute of Science and Technology Austria.
  mla: Schön, Hanna. <i>The ER Complex SUTU-7/MACO-1 Regulates the Fate of MRNAs Encoding
    GPCRs</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20167">10.15479/AT-ISTA-20167</a>.
  short: H. Schön, The ER Complex SUTU-7/MACO-1 Regulates the Fate of MRNAs Encoding
    GPCRs, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-13T11:13:13Z
date_published: 2025-08-13T00:00:00Z
date_updated: 2026-08-13T13:05:37Z
day: '13'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaDe
doi: 10.15479/AT-ISTA-20167
doi_confirm: '1'
file:
- access_level: closed
  checksum: b40c74404b8d9593802dabf57bfdf10f
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: hschoen
  date_created: 2025-09-08T14:33:50Z
  date_updated: 2025-09-09T08:57:04Z
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  creator: hschoen
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  date_updated: 2026-08-13T13:05:36Z
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file_date_updated: 2026-08-13T13:05:36Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa_version: Published Version
page: '171'
project:
- _id: 23870BE8-32DE-11EA-91FC-C7463DDC885E
  grant_number: 209504/A/17/Z
  name: Molecular mechanisms of neural circuit function
- _id: 23813290-32DE-11EA-91FC-C7463DDC885E
  grant_number: ALTF 302-2019
  name: Control of gene expression at the endoplasmic reticulum
publication_identifier:
  isbn:
  - 978-3-99078-061-9
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
title: The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding GPCRs
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '19684'
abstract:
- lang: eng
  text: "The overarching goal of this thesis is to break down the complexity of turbulent
    flows in terms of enumerable, coherent structures and patterns. In a five-paper
    series, we adopt a variety of perspectives and techniques to relate the properties
    of systems of increasing complexity to their underlying coherent structures. \r\n\r\nInitially,
    we take a dynamical systems point of view, seeing turbulent flow as a chaotic
    trajectory bouncing between exact unstable solutions of the underlying equations
    of motion. Using persistent homology, the main tool of topological data analysis
    capturing the persistence across scales of topological features in a point cloud,
    we introduce a method that quantifies visits of turbulent trajectories to unstable
    time-periodic solutions, also called periodic orbits. We demonstrate this method
    first in the Rössler and Kuramoto–Sivashinsky systems. Using this method in 3D
    Kolmogorov flow, we extract a Markov chain from turbulent data, where each node
    corresponds to the neighbourhood of a periodic orbit. The invariant distribution
    of this Markov chain reproduces expectation values on turbulent data when it is
    used to weight averages on the respective periodic orbits.\r\n\r\nIn more realistic,
    wall-bounded settings, such as plane-Couette flow (pcf) driven by the relative
    motion of the walls, or plane-Poiseuille flow (ppf) driven by a pressure gradient,
    finding exact solutions is difficult. We use dynamic mode decomposition (DMD),
    a dimensionality reduction method for sequential data, to identify and approximate
    low-dimensional dynamics without knowing any exact solutions. Most spatially-extended
    systems are equivariant under translations, and in such cases spatial drifts dominate
    DMD, hindering its use in the search for and modelling of low-dimensional dynamics.
    We augment DMD with a symmetry reduction method trained on turbulent data to stop
    it from seeing translations as a feature, improving its ability to extract dynamical
    information in translation-equivariant systems. We find segments of turbulent
    trajectories that linearize well with their symmetry-reduced DMD spectra, akin
    to dynamics near exact solutions. Searching for harmonics in the spectra gives
    leads for periodic orbits with spatial drifts, one of which converges to a new
    solution.\r\n\r\nIn larger domains, turbulence can localize and coexist with surrounding
    laminar flow. Our preceding approaches are global, taking all of a domain into
    account at once, and cannot readily treat each localized patch individually. Working
    first in a minimal oblique domain that can host a single 1D-localized turbulent
    patch, we find that turbulence in ppf is connected to a stable periodic orbit
    at a flow velocity much lower than when turbulence is first onset. We show that,
    well in advance of sustained turbulence, chaos sets in explosively, and for long
    time horizons, time series are consistent with that of a random process.\r\n\r\nFinally,
    in much larger domains, we study and compare 2D-localized turbulence that appears
    as large-scale inclined structures, called stripes, in ppf and pcf. While appearing
    similar, we find that stripes in these two settings differ significantly in terms
    of how they sustain themselves, and in higher velocities, how they proliferate."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "The work in this thesis was supported by a grant from the Simons
  Foundation (662960, BH).\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Gökhan
  full_name: Yalniz, Gökhan
  id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425
  last_name: Yalniz
  orcid: 0000-0002-8490-9312
citation:
  ama: 'Yalniz G. Transition to turbulence: Data-, solution-, and pattern-driven approaches.
    2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19684">10.15479/AT-ISTA-19684</a>'
  apa: 'Yalniz, G. (2025). <i>Transition to turbulence: Data-, solution-, and pattern-driven
    approaches</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-19684">https://doi.org/10.15479/AT-ISTA-19684</a>'
  chicago: 'Yalniz, Gökhan. “Transition to Turbulence: Data-, Solution-, and Pattern-Driven
    Approaches.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-19684">https://doi.org/10.15479/AT-ISTA-19684</a>.'
  ieee: 'G. Yalniz, “Transition to turbulence: Data-, solution-, and pattern-driven
    approaches,” Institute of Science and Technology Austria, 2025.'
  ista: 'Yalniz G. 2025. Transition to turbulence: Data-, solution-, and pattern-driven
    approaches. Institute of Science and Technology Austria.'
  mla: 'Yalniz, Gökhan. <i>Transition to Turbulence: Data-, Solution-, and Pattern-Driven
    Approaches</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19684">10.15479/AT-ISTA-19684</a>.'
  short: 'G. Yalniz, Transition to Turbulence: Data-, Solution-, and Pattern-Driven
    Approaches, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-05-12T15:12:28Z
date_published: 2025-05-13T00:00:00Z
date_updated: 2026-09-02T08:16:32Z
day: '13'
ddc:
- '514'
- '519'
- '532'
- '004'
degree_awarded: PhD
department:
- _id: GradSch
- _id: BjHo
doi: 10.15479/AT-ISTA-19684
doi_confirm: '1'
file:
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  checksum: 0e452642b79f13633f1595bde71a67e3
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  creator: gyalniz
  date_created: 2025-05-12T15:13:28Z
  date_updated: 2025-05-12T15:13:28Z
  file_id: '19685'
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  success: 1
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:15:59Z
  date_updated: 2025-05-12T15:43:28Z
  description: '3D visualizations of the turbulent flow (left) and the periodic orbits
    (middle) that are being shadowed along with the local state space projections
    (right) onto the principal components of the respective periodic orbit. Shown
    here are the isosurfaces of velocity (red/blue: ±95% of the instantaneous maximum)
    and vorticity (purple/green: ±65% of the instantaneous maximum) in the x-direction.
    Markers along the projections are in sync with the 3D visualizations. The movie
    corresponds to the initial time interval (up to t = 100) of figure 2.2 (a,b);
    periodic orbits and the state space projections are shown only through the shadowing
    events indicated in figure 2.2 (b).'
  file_id: '19686'
  file_name: Movie 2A.1.mp4
  file_size: 37763743
  relation: supplementary_material
  title: Chapter 2 - Movie 2A.1
- access_level: open_access
  checksum: 0ae5ac7d9896003c0c4207dd746808dc
  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:09Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Turbulent flow (left) in HKW domain and its symmetry reduction (right).
    Shown here are the isosurfaces of streamwise velocity (red/blue: u = 0.5 max/min
    u) and streamwise vorticity (green/purple: ω_x = 0.5 max/min ω_x).'
  file_id: '19687'
  file_name: Movie 3A.1.mp4
  file_size: 3902655
  relation: supplementary_material
  title: Chapter 3 - Movie 3A.1
- access_level: open_access
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:21Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Turbulent flow (left) in P2K domain and its symmetry reduction (right).
    Shown here are the isosurfaces of streamwise velocity (red/blue: u = 0.5 max/min
    u) and streamwise vorticity (green/purple: ω_x = 0.5 max/min ω_x).'
  file_id: '19688'
  file_name: Movie 3A.2.mp4
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:36Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Relative periodic orbit RPO_79.4 (left) of the plane-Couette flow
    (HKW domain) and its symmetry reduction (right). Shown here are the isosurfaces
    of streamwise velocity (red/blue: u = 0.5 max/min u) and streamwise vorticity
    (green/purple: ω_x = 0.5 max/min ω_x).'
  file_id: '19689'
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:16:50Z
  date_updated: 2025-05-12T15:43:28Z
  description: 'Symmetry-reduced flow (left), its SRDMD approximation (middle), and
    state space projection (right) showing the spiral-out episode in P2K domain (figure
    3.6 (b) and figure 3.8 (b)). Shown here are the isosurfaces of streamwise velocity
    (red/blue: u = 0.5 max/min u) and streamwise vorticity (green/purple: ω_x = 0.5
    max/min ω_x).'
  file_id: '19690'
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  file_size: 5873052
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  title: Chapter 3 - Movie 3A.4
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:11Z
  date_updated: 2025-05-12T15:43:28Z
  description: Movie demonstrating the quasi-steady Reynolds number descent from turbulence
    to a periodic orbit.
  file_id: '19691'
  file_name: Movie 4A.1.mp4
  file_size: 9209327
  relation: supplementary_material
  title: Chapter 4 - Movie 4A.1
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:43Z
  date_updated: 2025-05-12T15:43:28Z
  description: Streamwise velocity fluctuations (from laminar) of plane-Couette flow
    (Re^C =335) at the y = 0 wall-normal plane in coordinates stationary with respect
    to the bulk velocity. Here, x is the streamwise direction (the wall at y = 1 moves
    to the right) and z is the spanwise direction. Time is in advectime time units.
    Shown is the full (L_x = L_z = 400) domain.
  file_id: '19692'
  file_name: Movie 5A.1.mp4
  file_size: 5893993
  relation: supplementary_material
  title: Chapter 5 - Movie 5A.1
- access_level: open_access
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:49Z
  date_updated: 2025-05-12T15:43:28Z
  description: Streamwise velocity fluctuations (from laminar) of plane-Poiseuille
    flow (Re^P =660) at the y = 0.5 wall-normal plane in coordinates stationary with
    respect to the bulk velocity. Here, x is the streamwise direction (the mean negative
    pressure gradient is to the right) and z is the spanwise direction. Time is in
    advectime time units. Shown is the full (L_x = L_z = 400) domain.
  file_id: '19693'
  file_name: Movie 5A.2.mp4
  file_size: 3990352
  relation: supplementary_material
  title: Chapter 5 - Movie 5A.2
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  content_type: video/mp4
  creator: gyalniz
  date_created: 2025-05-12T15:17:58Z
  date_updated: 2025-05-12T15:43:28Z
  description: Streamwise velocity fluctuations (from laminar) of plane-Poiseuille
    flow (Re^P=660) at the y = 0.5 wall-normal plane in coordinates stationary with
    respect to the average velocity of the downstream tip of the stripe. Here, x is
    the streamwise direction (the mean negative pressure gradient is to the right)
    and z is the spanwise direction. Time is in advectime time units. Shown is a zoom-in
    of the full (L_x = L_z) domain.
  file_id: '19694'
  file_name: Movie 5A.3.mp4
  file_size: 5171009
  relation: supplementary_material
  title: Chapter 5 - Movie 5A.3
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  creator: gyalniz
  date_created: 2025-05-12T15:27:10Z
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file_date_updated: 2025-05-12T15:43:28Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '155'
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
  grant_number: '662960'
  name: Revisiting the Turbulence Problem Using Statistical Mechanics
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
  - id: '12105'
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  - id: '13274'
    relation: part_of_dissertation
    status: public
  - id: '14466'
    relation: part_of_dissertation
    status: public
  - id: '7563'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
title: 'Transition to turbulence: Data-, solution-, and pattern-driven approaches'
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20117'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
acknowledgement: "I would also like to acknowledge the invaluable assistance provided
  by the Plant\r\nFacility, Imaging & Optics Facility, and the Lab Support Facility.
  The technical support and\r\nresources offered by these facilities were indispensable
  to the successful completion of my\r\nexperiments."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Yiqun
  full_name: Wang, Yiqun
  id: 82F537F2-B517-11E9-84D7-6433E6697425
  last_name: Wang
citation:
  ama: Wang Y. The role of dynamin related protein 2A in cytokinin regulated plant
    growth and development. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20117">10.15479/AT-ISTA-20117</a>
  apa: Wang, Y. (2025). <i>The role of dynamin related protein 2A in cytokinin regulated
    plant growth and development</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-20117">https://doi.org/10.15479/AT-ISTA-20117</a>
  chicago: Wang, Yiqun. “The Role of Dynamin Related Protein 2A in Cytokinin Regulated
    Plant Growth and Development.” Institute of Science and Technology Austria, 2025.
    <a href="https://doi.org/10.15479/AT-ISTA-20117">https://doi.org/10.15479/AT-ISTA-20117</a>.
  ieee: Y. Wang, “The role of dynamin related protein 2A in cytokinin regulated plant
    growth and development,” Institute of Science and Technology Austria, 2025.
  ista: Wang Y. 2025. The role of dynamin related protein 2A in cytokinin regulated
    plant growth and development. Institute of Science and Technology Austria.
  mla: Wang, Yiqun. <i>The Role of Dynamin Related Protein 2A in Cytokinin Regulated
    Plant Growth and Development</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20117">10.15479/AT-ISTA-20117</a>.
  short: Y. Wang, The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant
    Growth and Development, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-04T15:24:21Z
date_published: 2025-08-04T00:00:00Z
date_updated: 2026-09-03T22:30:04Z
day: '04'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/AT-ISTA-20117
file:
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  file_name: 2025_Wang_Yiqun_Thesis.docx
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  content_type: application/pdf
  creator: yiqwang
  date_created: 2025-08-22T10:32:30Z
  date_updated: 2026-09-03T22:30:03Z
  embargo: 2026-09-03
  file_id: '20211'
  file_name: 2025_Wang_Yiqun_Thesis.pdf
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file_date_updated: 2026-09-03T22:30:03Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '108'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '18063'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
title: The role of dynamin related protein 2A in cytokinin regulated plant growth
  and development
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: publisher
_id: '20212'
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: "I would also like to\r\nthank the Austrian Academy of Sciences for
  awarding me a 2-year DOC fellowship\r\n(DOC26253)."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Osvaldo
  full_name: Miranda, Osvaldo
  id: 862A3C56-A8BF-11E9-B4FA-D9E3E5697425
  last_name: Miranda
  orcid: 0000-0001-6618-6889
citation:
  ama: Miranda O. Unraveling the role of Pten in cortical stem cell lineage progression
    using MADM. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20212">10.15479/AT-ISTA-20212</a>
  apa: Miranda, O. (2025). <i>Unraveling the role of Pten in cortical stem cell lineage
    progression using MADM</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20212">https://doi.org/10.15479/AT-ISTA-20212</a>
  chicago: Miranda, Osvaldo. “Unraveling the Role of Pten in Cortical Stem Cell Lineage
    Progression Using MADM.” Institute of Science and Technology Austria, 2025. <a
    href="https://doi.org/10.15479/AT-ISTA-20212">https://doi.org/10.15479/AT-ISTA-20212</a>.
  ieee: O. Miranda, “Unraveling the role of Pten in cortical stem cell lineage progression
    using MADM,” Institute of Science and Technology Austria, 2025.
  ista: Miranda O. 2025. Unraveling the role of Pten in cortical stem cell lineage
    progression using MADM. Institute of Science and Technology Austria.
  mla: Miranda, Osvaldo. <i>Unraveling the Role of Pten in Cortical Stem Cell Lineage
    Progression Using MADM</i>. Institute of Science and Technology Austria, 2025,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-20212">10.15479/AT-ISTA-20212</a>.
  short: O. Miranda, Unraveling the Role of Pten in Cortical Stem Cell Lineage Progression
    Using MADM, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-22T14:07:00Z
date_published: 2025-08-22T00:00:00Z
date_updated: 2026-08-26T22:30:03Z
day: '22'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: SiHi
doi: 10.15479/AT-ISTA-20212
file:
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  creator: omiranda
  date_created: 2025-08-26T09:05:55Z
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  file_size: 28636240
  relation: main_file
file_date_updated: 2026-08-26T22:30:02Z
has_accepted_license: '1'
keyword:
- Pten
- mtor
- cortical development
- MADM
- Mapk
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '119'
project:
- _id: 34c9fbcb-11ca-11ed-8bc3-98fa5658610d
  grant_number: '26253'
  name: Molecular Mechanisms Regulating Cortical Neural Stem Cell Lineage Progression
    and Astrocyte Development
publication_identifier:
  isbn:
  - 978-3-99078-063-3
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17425'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
title: Unraveling the role of Pten in cortical stem cell lineage progression using
  MADM
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_embargo: '6'
OA_place: publisher
_id: '20798'
abstract:
- lang: eng
  text: "Atom interferometers measure the relative phase shifts between coherent matter-wave
    paths\r\nthat arise from interactions with external fields or inertial forces.
    Due to their exceptional\r\nphase sensitivity, atom interferometers became an
    essential tool for precision measurements\r\nand fundamental physics experiments,
    finding applications in geodesy, gravimetry, and inertial\r\nnavigation. However,
    their measurement precision is limited by quantum projection noise,\r\nwhich arises
    from the Heisenberg uncertainty principle, preventing the measurement of atomic\r\nstates
    with absolute precision. The generation of entanglement between the atoms offers
    a\r\npath to surpass this so-called standard quantum limit, thereby enhancing
    the interferometer’s\r\nphase sensitivity beyond classical measurement bounds.\r\nThis
    thesis reports on the development of an atom interferometer experiment designed
    to\r\nrealize cavity-mediated, squeezed Mach-Zehnder-type interferometry with
    ultra-cold 87Rb atoms.\r\nThe experiment combines cavity-aided spin-squeezing
    with cavity-mediated Mach-Zehnder\r\ninterferometry to demonstrate entanglement-enhanced
    phase sensitivity. The experiment is\r\ncentered on a triangular optical cavity
    that mediates all relevant atom-light interactions. The\r\ncavity provides optical
    trapping, spin-squeezing, and Raman beam-splitter operations, enabling\r\nto perform
    interferometry on a continuously trapped atomic ensemble.\r\nThe thesis elaborates
    on the fundamental theoretical framework, the cavity design, and the full\r\noptical
    setup, including the detailed configuration of the developed laser stabilization
    methods.\r\nExperimentally, continuous loading methods were explored, resulting
    in an accumulation of\r\nup to 4 × 106\r\natoms in the dipole trap within a cycle
    time of 500 ms. The AC Stark shift\r\ncompensation method developed for continuous
    loading was further applied for in-trap cooling\r\nto 10 µK, and optical pumping
    for efficient atomic state preparation. Coherent state control\r\nwas verified
    via observation of microwave-driven Rabi oscillations, and used to characterize\r\natom-cavity
    coupling.\r\nThese presented results establish the experimental groundwork for
    the future development of\r\ncavity-mediated, entanglement-enhanced Mach-Zehnder-type
    atom interferometry."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Sebastian
  full_name: Wald, Sebastian
  id: 133F200A-B015-11E9-AD41-0EDAE5697425
  last_name: Wald
  orcid: 0000-0002-5869-1604
citation:
  ama: Wald S. Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry.
    2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20798">10.15479/AT-ISTA-20798</a>
  apa: Wald, S. (2025). <i>Atoms in a propagating-wave cavity for squeezed Mach-Zehnder
    atom interferometry</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20798">https://doi.org/10.15479/AT-ISTA-20798</a>
  chicago: Wald, Sebastian. “Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder
    Atom Interferometry.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20798">https://doi.org/10.15479/AT-ISTA-20798</a>.
  ieee: S. Wald, “Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom
    interferometry,” Institute of Science and Technology Austria, 2025.
  ista: Wald S. 2025. Atoms in a propagating-wave cavity for squeezed Mach-Zehnder
    atom interferometry. Institute of Science and Technology Austria.
  mla: Wald, Sebastian. <i>Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder
    Atom Interferometry</i>. Institute of Science and Technology Austria, 2025, doi:<a
    href="https://doi.org/10.15479/AT-ISTA-20798">10.15479/AT-ISTA-20798</a>.
  short: S. Wald, Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom
    Interferometry, Institute of Science and Technology Austria, 2025.
corr_author: '1'
das_tickbox: '1'
date_created: 2025-12-11T11:48:11Z
date_published: 2025-12-11T00:00:00Z
date_updated: 2026-07-24T08:07:28Z
day: '11'
ddc:
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: OnHo
doi: 10.15479/AT-ISTA-20798
doi_confirm: '1'
file:
- access_level: open_access
  checksum: 1be72faf529a5e8a2d03cb3d5f808b77
  content_type: application/pdf
  creator: swald
  date_created: 2025-12-12T11:53:42Z
  date_updated: 2026-06-15T22:30:03Z
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keyword:
- entanglement-enhanced atom interferometry
- cavity QED
- spin-squeezing
- dipole trap
- quantum optics
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '152'
publication_identifier:
  isbn:
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  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '14759'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
title: Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '18871'
abstract:
- lang: eng
  text: "\"Can we do this with a new type of computer - a quantum computer?\". This
    famous\r\nquotation of the brilliant Richard Feynman within a conference talk
    on \"Simulating physics\r\nwith computers.” is often reverently praised as the
    origin of the field of quantum computing.\r\nThe idea was to use quantum mechanical
    systems itself to simulate \"Nature\", which is\r\ninherently quantum mechanical.
    Now, 43 years later, the theoretical framework of how such\r\na computer can operate
    has been developed. Two main important concepts for a potential\r\nquantum supremacy,
    superposition and entanglement, have been exploited to design quantum\r\nalgorithms
    to significantly speed up certain tasks. Yet, the specific hardware implementation\r\nis
    still far from being certain, in fact the race between the most promising platforms
    such as\r\nsuperconducting qubits, bosonic codes, cold atoms, trapped ions, optical
    computing as well\r\nas spin qubits has recently intensified. If one also includes
    the most mature applications of\r\nquantum communication technologies, secure
    quantum key distribution and quantum random\r\nnumber generators, as part of a
    quantum information technology ecosystem, we are confronted\r\nwith a plethora
    of different materials, concepts, and also operation frequencies. While\r\nsuperconducting
    qubits, bosonic codes and spin qubits work in the regime of approximately 5\r\nGHz
    and are controlled by electrical fields, trapped ions, cold atoms, and optical
    quantum\r\ncomputing operate with light in the infrared or visible range.\r\nConsequently,
    a quantum frequency converter or microwave-optic transducer is required\r\nto
    interface the different frequency domains or establish a long-range network connection\r\nwith
    suitable telecom fibers. In fact, the combination of different frequency regimes
    is also\r\nan essential part in our classical modern communication network, where
    computations are\r\nperformed in electrical circuits and the information exchange
    over longer distances happens\r\nvia optical fibers. However, the specific challenges
    specific to building a quantum computer,\r\nalso apply to the development of such
    a quantum frequency transducer: 1) As we deal with\r\nsingle excitations as the
    carrier of information, i.e. the smallest possible quantity, the signal\r\ncan
    easily be corrupted by other noise sources which needs to be avoided by all means.
    This\r\nis also the reason why microwave quantum computers operate at temperature
    environments\r\nclose to zero temperature (< 0.1 Kelvin) to avoid corruption by
    thermal noise. 2) The\r\nfrequency interface generally needs to preserve the phase
    of the signal as an essential part\r\nof the quantum state. And 3) Quantum signals
    cannot be copied which would be a typical\r\nstrategy to account for errors in
    classical computers. And finally, there is a challenge specific to\r\nmicrowave-optic
    transducers: While quantum computers are operating in one specific frequency\r\ndomain,
    microwave-optic transducers combine microwave and optical fields in one device.\r\nThis
    results in the particular challenge that high-energy optical radiation, which
    is usually\r\nwell-shielded from superconducting microwave quantum processors,
    are now an essential part\r\nof the device. The concomitant optical radiation
    in the operating transducer will inevitably\r\nhave a detrimental effect on the
    superconducting microwave components. Together with the\r\nrequirement of minimal
    background noise for quantum-limited operation as described above,\r\nv\r\nheating
    from the absorption of optical photons within the same device where single microwave\r\nexcitations
    are processed forms a formidable challenge.\r\nThis thesis aims to address this
    challenge by developing microwave-optic transducers where\r\nthe impact of optical
    absorption on superconducting circuits in general and superconducting\r\nqubits
    specifically can be mitigated. In our first approach, we developed a compact device\r\nwith
    optimized interaction strengths between the different frequency domains. This
    minimizes\r\nthe optical powers used for transducer operation and thus the optical
    absorption heating. This\r\nwork was - to the best of our knowledge - the first
    comprehensive noise study, in an integrated\r\nmicrowave-optic transducer. Unfortunately,
    we saw that the optical absorption heating added\r\nnoise way above a single excitation.
    Consequently, a potential quantum signal would have\r\nbeen buried in the noise,
    added by the transduction.\r\nBuilding on this insight, we utilized a three-dimensional
    microwave-optic transducer instead\r\nof an integrated device. The larger heat
    capacity of the macroscopic device with a size\r\nof a few millimeters can absorb
    a larger fraction of the optical heating before it increases\r\nthe temperature
    of the device. This allowed us to interface the transducer directly with a\r\nsuperconducting
    qubit to readout the qubit state in a novel all-optical manner. We showed\r\nthat
    the microwave-optic transducer can be operated in a regime in which optical fields
    don’t\r\nharm the sensitive qubit. This is an important prerequisite for the operation
    of microwave-optic\r\ntransducers in conjunction with microwave quantum processors
    and brings the integration and\r\nseamless orchestration of different frequency
    components in a quantum network a step closer.\r\n"
acknowledged_ssus:
- _id: SSU
- _id: M-Shop
- _id: NanoFab
acknowledgement: "This work was supported by the European Research Council under grant
  agreement no. 758053\r\n(ERC StG QUNNECT) and the European Union’s Horizon 2020
  research, innovation program\r\nunder grant agreement no. 899354 (FETopen SuperQuLAN)
  and the Austrian Science Fund\r\n(FWF) through BeyondC (F7105). I want to acknowledge
  generous support from the Austrian\r\nAcademy of Sciences from a DOC [Doctoral program
  of the Austrian Academy of Sciences]\r\nfellowship (no. 25129).\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Georg M
  full_name: Arnold, Georg M
  id: 3770C838-F248-11E8-B48F-1D18A9856A87
  last_name: Arnold
  orcid: 0000-0003-1397-7876
citation:
  ama: Arnold GM. Microwave-optic interconnects for superconducting circuits. 2025.
    doi:<a href="https://doi.org/10.15479/at:ista:18871">10.15479/at:ista:18871</a>
  apa: Arnold, G. M. (2025). <i>Microwave-optic interconnects for superconducting
    circuits</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18871">https://doi.org/10.15479/at:ista:18871</a>
  chicago: Arnold, Georg M. “Microwave-Optic Interconnects for Superconducting Circuits.”
    Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/at:ista:18871">https://doi.org/10.15479/at:ista:18871</a>.
  ieee: G. M. Arnold, “Microwave-optic interconnects for superconducting circuits,”
    Institute of Science and Technology Austria, 2025.
  ista: Arnold GM. 2025. Microwave-optic interconnects for superconducting circuits.
    Institute of Science and Technology Austria.
  mla: Arnold, Georg M. <i>Microwave-Optic Interconnects for Superconducting Circuits</i>.
    Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/at:ista:18871">10.15479/at:ista:18871</a>.
  short: G.M. Arnold, Microwave-Optic Interconnects for Superconducting Circuits,
    Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-01-24T10:28:39Z
date_published: 2025-01-24T00:00:00Z
date_updated: 2026-04-16T12:20:43Z
day: '24'
ddc:
- '530'
degree_awarded: PhD
department:
- _id: JoFi
- _id: GradSch
doi: 10.15479/at:ista:18871
ec_funded: 1
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has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '135'
project:
- _id: 26336814-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '758053'
  name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 9B868D20-BA93-11EA-9121-9846C619BF3A
  call_identifier: H2020
  grant_number: '899354'
  name: Quantum Local Area Networks with Superconducting Qubits
- _id: 2671EB66-B435-11E9-9278-68D0E5697425
  name: Coherent on-chip conversion of superconducting qubit signals from microwaves
    to optical frequencies
- _id: bdb108fd-d553-11ed-ba76-83dc74a9864f
  grant_number: F07105
  name: QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration
    of Superconducting Quantum Circuits
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: part_of_dissertation
    status: public
  - id: '10924'
    relation: part_of_dissertation
    status: public
  - id: '9114'
    relation: part_of_dissertation
    status: public
  - id: '13200'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
title: Microwave-optic interconnects for superconducting circuits
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  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_embargo: '6'
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abstract:
- lang: eng
  text: "Cell migration is a crucial process in animal development and maintenance.
    It is incredibly\r\nheterogeneous, with different cell types utilizing fundamentally
    distinct migration strategies.\r\nThe strategies also depend on the cellular microenvironment,
    where cells can switch between\r\nmigration modes as they encounter new environmental
    cues. In this thesis, we investigated\r\nhow dendritic cells adapt their migration
    strategy when encountering geometrically,\r\nmechanically and chemically distinct
    environments.\r\nWhen dendritic cells are embedded in a homogeneous fibrous network,
    they migrate in a fast\r\nand directional amoeboid manner. In this migration strategy,
    extracellular proteolysis and\r\nintegrin-mediated adhesions are dispensable.
    Instead, the cells use topography of the\r\nenvironment to propel their cell body
    forward. To migrate efficiently in the maze of different\r\npore sizes, they position
    the nucleus ahead of the microtubule organizing center (MTOC) and\r\nuse it to
    gauge the pores to identify the path of least resistance. Our aim was to identify\r\nwhether
    dendritic cells adapt their migration strategy when encountering asymmetrical\r\ntransitions
    into much denser environments with limited choice of large pores. In such invasive\r\ntransitions
    it is unclear if the cells can cross tight pores without the use of adhesions
    and\r\nextracellular proteolysis and whether they maintain the nucleus in the
    cell front.\r\nUsing various cell migration assays such as fibrous 3D collagen
    gels, geometrically defined\r\nmicrochannels with constrictions and simplistic
    under agarose migration assay, we provide\r\na comprehensive characterization
    of invasive migration of dendritic cells. We show that\r\nduring invasion the
    cells stall and stretch, reflecting the difficulty to translocate the bulky cell\r\nbody
    into the dense environment. In collagen gels, we show that dendritic cells can
    invade\r\nwithout proteolysis and adhesions. Instead, they utilize contractility,
    which can lead to largescale collagen compressions. During invasion, the nucleus
    stalls at tight constrictions, leading\r\nto a transient organelle reorientation.
    To resolve the stalling, upregulated rear contractility is\r\nrequired. This contractile
    force is simultaneously necessary for reverting the nucleus back to\r\nthe cell
    front after invasion and maintaining this positioning during permissive migration.\r\nA
    functional role of the reorientation was uncovered in the first collaboration
    project.\r\nA prominent central actin pool was identified around the MTOC, especially
    pronounced in\r\ndense and compressive environments. The actin pool was shown
    to generate pushing forces\r\nto dilate the space for cell translocation. These
    forces are only necessary in non-permissive\r\nenvironments, where the nucleus
    reorients to the cell rear, allowing the actin pool to\r\ngenerate space. In permissive
    environments where space generation is dispensable, the\r\nMTOC is located behind
    the nucleus and the actin cloud has reduced intensity, allowing more\r\nactin
    to be incorporated into the lamellipodium, speeding up migration.\r\nIn the second
    collaboration project, we investigated the effects of distinct chemical\r\nenvironments
    on dendritic cell migration. The strikingly persistent migration of these cells\r\nwas
    explained by their ability to modulate and even self-generate chemokine gradients.
    This\r\nallows the cells to migrate faster and more persistent in uniform chemokine
    fields compared\r\nto imposed chemokine gradients. The chemokine receptor CCR7
    was identified as a crucial\r\nplayer in this process, both sensing the signal
    and internalizing the chemokine to create a sink."
acknowledgement: "This project has received funding from the Austrian Science Fund
  (FWF) via the doctorate\r\ncollege DK NanoCell and from the European Union’s Horizon
  2020 research and innovation\r\nprogramme under the Marie Skłodowska-Curie Grant
  Agreement No. 665385.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Nikola
  full_name: Canigova, Nikola
  id: 3795523E-F248-11E8-B48F-1D18A9856A87
  last_name: Canigova
  orcid: 0000-0002-8518-5926
citation:
  ama: Canigova N. Adaptive strategies of dendritic cell migration in response to
    environmental cues. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19745">10.15479/AT-ISTA-19745</a>
  apa: Canigova, N. (2025). <i>Adaptive strategies of dendritic cell migration in
    response to environmental cues</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-19745">https://doi.org/10.15479/AT-ISTA-19745</a>
  chicago: Canigova, Nikola. “Adaptive Strategies of Dendritic Cell Migration in Response
    to Environmental Cues.” Institute of Science and Technology Austria, 2025. <a
    href="https://doi.org/10.15479/AT-ISTA-19745">https://doi.org/10.15479/AT-ISTA-19745</a>.
  ieee: N. Canigova, “Adaptive strategies of dendritic cell migration in response
    to environmental cues,” Institute of Science and Technology Austria, 2025.
  ista: Canigova N. 2025. Adaptive strategies of dendritic cell migration in response
    to environmental cues. Institute of Science and Technology Austria.
  mla: Canigova, Nikola. <i>Adaptive Strategies of Dendritic Cell Migration in Response
    to Environmental Cues</i>. Institute of Science and Technology Austria, 2025,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-19745">10.15479/AT-ISTA-19745</a>.
  short: N. Canigova, Adaptive Strategies of Dendritic Cell Migration in Response
    to Environmental Cues, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-05-26T08:49:00Z
date_published: 2025-05-27T00:00:00Z
date_updated: 2026-06-18T17:34:48Z
day: '27'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: MiSi
- _id: GradSch
doi: 10.15479/AT-ISTA-19745
ec_funded: 1
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page: '133'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 265E2996-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: W01250-B20
  name: Nano-Analytics of Cellular Systems
publication_identifier:
  isbn:
  - 978-3-99078-058-9
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '14274'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
title: Adaptive strategies of dendritic cell migration in response to environmental
  cues
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
