@article{21527,
  abstract     = {Optical metasurfaces have been heralded as the platform to integrate multiple functionalities in a compact form-factor, with the potential to replace bulky optical components. A central stepping stone toward realizing this promise is the demonstration of multifunctionality under several constraints (e.g., at multiple incident wavelengths and/or angles) in a single device, an achievement being hampered by design limitations inherent to single-layer planar geometries. Here, we propose a framework for the inverse design of multilayer metaoptics via topology optimization, showing that even few-wavelength thick devices can achieve high-efficiency multifunctionality, such as multiangle light concentration and plan-achromaticity. We embody our framework in multiple closely spaced patterned layers of a low-index polymer, with fabrication constraints specific to this platform enforced in the optimization process. We experimentally demonstrate our approach with an inverse-designed 3D-printed light concentrator working at five different nonparaxial angles of incidence. Our framework paves the way toward realizing multifunctional ultracompact 3D nanophotonic devices.},
  author       = {Roques-Carmes, Charles and Lin, Zin and Christiansen, Rasmus E. and Salamin, Yannick and Kooi, Steven E. and Joannopoulos, John D. and Johnson, Steven G. and Soljačić, Marin},
  issn         = {2330-4022},
  journal      = {ACS Photonics},
  keywords     = {metasurfaces, inverse design, multilayered metaoptics, 3D printing, topology optimization},
  number       = {1},
  pages        = {43--51},
  publisher    = {American Chemical Society},
  title        = {{Toward 3D-printed inverse-designed metaoptics}},
  doi          = {10.1021/acsphotonics.1c01442},
  volume       = {9},
  year         = {2022},
}

@article{8586,
  abstract     = {Cryo-electron microscopy (cryo-EM) of cellular specimens provides insights into biological processes and structures within a native context. However, a major challenge still lies in the efficient and reproducible preparation of adherent cells for subsequent cryo-EM analysis. This is due to the sensitivity of many cellular specimens to the varying seeding and culturing conditions required for EM experiments, the often limited amount of cellular material and also the fragility of EM grids and their substrate. Here, we present low-cost and reusable 3D printed grid holders, designed to improve specimen preparation when culturing challenging cellular samples directly on grids. The described grid holders increase cell culture reproducibility and throughput, and reduce the resources required for cell culturing. We show that grid holders can be integrated into various cryo-EM workflows, including micro-patterning approaches to control cell seeding on grids, and for generating samples for cryo-focused ion beam milling and cryo-electron tomography experiments. Their adaptable design allows for the generation of specialized grid holders customized to a large variety of applications.},
  author       = {Fäßler, Florian and Zens, Bettina and Hauschild, Robert and Schur, Florian KM},
  issn         = {1047-8477},
  journal      = {Journal of Structural Biology},
  keywords     = {electron microscopy, cryo-EM, EM sample preparation, 3D printing, cell culture},
  number       = {3},
  publisher    = {Elsevier},
  title        = {{3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy}},
  doi          = {10.1016/j.jsb.2020.107633},
  volume       = {212},
  year         = {2020},
}