[{"language":[{"iso":"eng"}],"publication":"Chemical Communications","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","doi":"10.1039/d1cc07081a","publication_status":"published","type":"journal_article","quality_controlled":"1","abstract":[{"lang":"eng","text":"We show that the optical properties of indigo carmine can be modulated by encapsulation within a coordination cage. Depending on the host/guest molar ratio, the cage can predominantly encapsulate either one or two dye molecules. The 1 : 1 complex is fluorescent, unique for an indigo dye in an aqueous solution. We have also found that binding two dye molecules stabilizes a previously unknown conformation of the cage."}],"day":"22","page":"3461-3464","date_published":"2022-01-22T00:00:00Z","keyword":["Materials Chemistry","Metals and Alloys","Surfaces","Coatings and Films","General Chemistry","Ceramics and Composites","Electronic","Optical and Magnetic Materials","Catalysis"],"publication_identifier":{"eissn":["1364-548X"],"issn":["1359-7345"]},"fulldoi":"https://doi.org/10.1039/d1cc07081a","date_updated":"2024-10-14T12:10:24Z","year":"2022","oa_version":"Published Version","author":[{"first_name":"Oksana","full_name":"Yanshyna, Oksana","last_name":"Yanshyna"},{"first_name":"Liat","full_name":"Avram, Liat","last_name":"Avram"},{"full_name":"Shimon, Linda J. W.","last_name":"Shimon","first_name":"Linda J. W."},{"id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn","full_name":"Klajn, Rafal","first_name":"Rafal"}],"issue":"21","month":"01","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1039/D1CC07081A"}],"extern":"1","citation":{"mla":"Yanshyna, Oksana, et al. “Coexistence of 1:1 and 2:1 Inclusion Complexes of Indigo Carmine.” <i>Chemical Communications</i>, vol. 58, no. 21, Royal Society of Chemistry, 2022, pp. 3461–64, doi:<a href=\"https://doi.org/10.1039/d1cc07081a\">10.1039/d1cc07081a</a>.","ama":"Yanshyna O, Avram L, Shimon LJW, Klajn R. Coexistence of 1:1 and 2:1 inclusion complexes of indigo carmine. <i>Chemical Communications</i>. 2022;58(21):3461-3464. doi:<a href=\"https://doi.org/10.1039/d1cc07081a\">10.1039/d1cc07081a</a>","ista":"Yanshyna O, Avram L, Shimon LJW, Klajn R. 2022. Coexistence of 1:1 and 2:1 inclusion complexes of indigo carmine. Chemical Communications. 58(21), 3461–3464.","short":"O. Yanshyna, L. Avram, L.J.W. Shimon, R. Klajn, Chemical Communications 58 (2022) 3461–3464.","apa":"Yanshyna, O., Avram, L., Shimon, L. J. W., &#38; Klajn, R. (2022). Coexistence of 1:1 and 2:1 inclusion complexes of indigo carmine. <i>Chemical Communications</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d1cc07081a\">https://doi.org/10.1039/d1cc07081a</a>","ieee":"O. Yanshyna, L. Avram, L. J. W. Shimon, and R. Klajn, “Coexistence of 1:1 and 2:1 inclusion complexes of indigo carmine,” <i>Chemical Communications</i>, vol. 58, no. 21. Royal Society of Chemistry, pp. 3461–3464, 2022.","chicago":"Yanshyna, Oksana, Liat Avram, Linda J. W. Shimon, and Rafal Klajn. “Coexistence of 1:1 and 2:1 Inclusion Complexes of Indigo Carmine.” <i>Chemical Communications</i>. Royal Society of Chemistry, 2022. <a href=\"https://doi.org/10.1039/d1cc07081a\">https://doi.org/10.1039/d1cc07081a</a>."},"date_created":"2023-08-01T09:32:55Z","volume":58,"article_processing_charge":"No","publisher":"Royal Society of Chemistry","_id":"13353","article_type":"original","external_id":{"pmid":["35064258"]},"oa":1,"title":"Coexistence of 1:1 and 2:1 inclusion complexes of indigo carmine","intvolume":"        58","pmid":1,"status":"public"},{"fulldoi":"https://doi.org/10.2533/chimia.2022.520","keyword":["General Medicine","General Chemistry"],"publication_identifier":{"eissn":["2673-2424"],"issn":["0009-4293"]},"page":"520-528","date_published":"2022-06-29T00:00:00Z","abstract":[{"text":"Photoionization is a process taking place on attosecond time scales. How its properties evolve from isolated particles to the condensed phase is an open question of both fundamental and practical relevance. Here, we review recent work that has advanced the study of photoionization dynamics from atoms to molecules, clusters and the liquid phase. The first measurements of molecular photoionization delays have revealed the attosecond dynamics of electron emission from a molecular shape resonance and their sensitivity to the molecular potential. Using electron-ion coincidence spectroscopy these measurements have been extended from isolated molecules to clusters. A continuous increase of the delays with the water-cluster size has been observed up to a size of 4-5 molecules, followed by a saturation towards larger clusters. Comparison with calculations has revealed a correlation of the time delay with the spatial extension of the created electron hole. Using cylindrical liquid-microjet techniques, these measurements have also been extended to liquid water, revealing a delay relative to isolated water molecules that was very similar to the largest water clusters studied. Detailed modeling based on Monte-Carlo simulations confirmed that these delays are dominated by the contributions of the first two solvation shells, which agrees with the results of the cluster measurements. These combined results open the perspective of experimentally characterizing the delocalization of electronic wave functions in complex systems and studying their evolution on attosecond time scales.","lang":"eng"}],"day":"29","quality_controlled":"1","type":"journal_article","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.2533/chimia.2022.520","scopus_import":"1","publication":"Chimia","language":[{"iso":"eng"}],"status":"public","title":"Attosecond photoionization dynamics: from molecules over clusters to the liquid phase","intvolume":"        76","oa":1,"article_type":"original","_id":"13993","article_processing_charge":"No","citation":{"ista":"Gong X, Jordan I, Huppert M, Heck S, Baykusheva DR, Jelovina D, Schild A, Wörner HJ. 2022. Attosecond photoionization dynamics: from molecules over clusters to the liquid phase. Chimia. 76(6), 520–528.","ama":"Gong X, Jordan I, Huppert M, et al. Attosecond photoionization dynamics: from molecules over clusters to the liquid phase. <i>Chimia</i>. 2022;76(6):520-528. doi:<a href=\"https://doi.org/10.2533/chimia.2022.520\">10.2533/chimia.2022.520</a>","mla":"Gong, Xiaochun, et al. “Attosecond Photoionization Dynamics: From Molecules over Clusters to the Liquid Phase.” <i>Chimia</i>, vol. 76, no. 6, Swiss Chemical Society, 2022, pp. 520–28, doi:<a href=\"https://doi.org/10.2533/chimia.2022.520\">10.2533/chimia.2022.520</a>.","short":"X. Gong, I. Jordan, M. Huppert, S. Heck, D.R. Baykusheva, D. Jelovina, A. Schild, H.J. Wörner, Chimia 76 (2022) 520–528.","apa":"Gong, X., Jordan, I., Huppert, M., Heck, S., Baykusheva, D. R., Jelovina, D., … Wörner, H. J. (2022). Attosecond photoionization dynamics: from molecules over clusters to the liquid phase. <i>Chimia</i>. Swiss Chemical Society. <a href=\"https://doi.org/10.2533/chimia.2022.520\">https://doi.org/10.2533/chimia.2022.520</a>","ieee":"X. Gong <i>et al.</i>, “Attosecond photoionization dynamics: from molecules over clusters to the liquid phase,” <i>Chimia</i>, vol. 76, no. 6. Swiss Chemical Society, pp. 520–528, 2022.","chicago":"Gong, Xiaochun, Inga Jordan, Martin Huppert, Saijoscha Heck, Denitsa Rangelova Baykusheva, Denis Jelovina, Axel Schild, and Hans Jakob Wörner. “Attosecond Photoionization Dynamics: From Molecules over Clusters to the Liquid Phase.” <i>Chimia</i>. Swiss Chemical Society, 2022. <a href=\"https://doi.org/10.2533/chimia.2022.520\">https://doi.org/10.2533/chimia.2022.520</a>."},"date_created":"2023-08-09T13:08:15Z","volume":76,"publisher":"Swiss Chemical Society","main_file_link":[{"open_access":"1","url":"https://doi.org/10.2533/chimia.2022.520"}],"month":"06","extern":"1","issue":"6","year":"2022","oa_version":"Published Version","author":[{"first_name":"Xiaochun","full_name":"Gong, Xiaochun","last_name":"Gong"},{"first_name":"Inga","full_name":"Jordan, Inga","last_name":"Jordan"},{"first_name":"Martin","last_name":"Huppert","full_name":"Huppert, Martin"},{"first_name":"Saijoscha","last_name":"Heck","full_name":"Heck, Saijoscha"},{"id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva","full_name":"Baykusheva, Denitsa Rangelova","first_name":"Denitsa Rangelova"},{"full_name":"Jelovina, Denis","last_name":"Jelovina","first_name":"Denis"},{"full_name":"Schild, Axel","last_name":"Schild","first_name":"Axel"},{"first_name":"Hans Jakob","full_name":"Wörner, Hans Jakob","last_name":"Wörner"}],"date_updated":"2023-08-22T07:26:39Z"},{"language":[{"iso":"eng"}],"publication":"Nature Communications","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","doi":"10.1038/s41467-022-30673-1","publication_status":"published","quality_controlled":"1","type":"journal_article","abstract":[{"text":"In the evolutionary arms race against phage, bacteria have assembled a diverse arsenal of antiviral immune strategies. While the recently discovered DISARM (Defense Island System Associated with Restriction-Modification) systems can provide protection against a wide range of phage, the molecular mechanisms that underpin broad antiviral targeting but avoiding autoimmunity remain enigmatic. Here, we report cryo-EM structures of the core DISARM complex, DrmAB, both alone and in complex with an unmethylated phage DNA mimetic. These structures reveal that DrmAB core complex is autoinhibited by a trigger loop (TL) within DrmA and binding to DNA substrates containing a 5′ overhang dislodges the TL, initiating a long-range structural rearrangement for DrmAB activation. Together with structure-guided in vivo studies, our work provides insights into the mechanism of phage DNA recognition and specific activation of this widespread antiviral defense system.","lang":"eng"}],"day":"27","date_published":"2022-05-27T00:00:00Z","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"publication_identifier":{"issn":["2041-1723"]},"fulldoi":"https://doi.org/10.1038/s41467-022-30673-1","article_number":"2987","date_updated":"2024-06-04T06:16:38Z","oa_version":"Published Version","year":"2022","author":[{"id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","last_name":"Bravo","full_name":"Bravo, Jack Peter Kelly","first_name":"Jack Peter Kelly","orcid":"0000-0003-0456-0753"},{"first_name":"Cristian","full_name":"Aparicio-Maldonado, Cristian","last_name":"Aparicio-Maldonado"},{"full_name":"Nobrega, Franklin L.","last_name":"Nobrega","first_name":"Franklin L."},{"first_name":"Stan J. J.","full_name":"Brouns, Stan J. J.","last_name":"Brouns"},{"full_name":"Taylor, David W.","last_name":"Taylor","first_name":"David W."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-022-30673-1"}],"month":"05","extern":"1","volume":13,"article_processing_charge":"Yes","date_created":"2024-03-20T10:41:59Z","citation":{"ama":"Bravo JPK, Aparicio-Maldonado C, Nobrega FL, Brouns SJJ, Taylor DW. Structural basis for broad anti-phage immunity by DISARM. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-30673-1\">10.1038/s41467-022-30673-1</a>","ista":"Bravo JPK, Aparicio-Maldonado C, Nobrega FL, Brouns SJJ, Taylor DW. 2022. Structural basis for broad anti-phage immunity by DISARM. Nature Communications. 13, 2987.","mla":"Bravo, Jack Peter Kelly, et al. “Structural Basis for Broad Anti-Phage Immunity by DISARM.” <i>Nature Communications</i>, vol. 13, 2987, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-30673-1\">10.1038/s41467-022-30673-1</a>.","short":"J.P.K. Bravo, C. Aparicio-Maldonado, F.L. Nobrega, S.J.J. Brouns, D.W. Taylor, Nature Communications 13 (2022).","apa":"Bravo, J. P. K., Aparicio-Maldonado, C., Nobrega, F. L., Brouns, S. J. J., &#38; Taylor, D. W. (2022). Structural basis for broad anti-phage immunity by DISARM. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-30673-1\">https://doi.org/10.1038/s41467-022-30673-1</a>","ieee":"J. P. K. Bravo, C. Aparicio-Maldonado, F. L. Nobrega, S. J. J. Brouns, and D. W. Taylor, “Structural basis for broad anti-phage immunity by DISARM,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","chicago":"Bravo, Jack Peter Kelly, Cristian Aparicio-Maldonado, Franklin L. Nobrega, Stan J. J. Brouns, and David W. Taylor. “Structural Basis for Broad Anti-Phage Immunity by DISARM.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-30673-1\">https://doi.org/10.1038/s41467-022-30673-1</a>."},"publisher":"Springer Nature","_id":"15133","article_type":"original","external_id":{"pmid":["35624106"]},"oa":1,"title":"Structural basis for broad anti-phage immunity by DISARM","intvolume":"        13","pmid":1,"status":"public"},{"_id":"15134","article_type":"original","external_id":{"pmid":["35595728"]},"citation":{"chicago":"Schwartz, Evan A., Tess M. McBride, Jack Peter Kelly Bravo, Daniel Wrapp, Peter C. Fineran, Robert D. Fagerlund, and David W. Taylor. “Structural Rearrangements Allow Nucleic Acid Discrimination by Type I-D Cascade.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-30402-8\">https://doi.org/10.1038/s41467-022-30402-8</a>.","ieee":"E. A. Schwartz <i>et al.</i>, “Structural rearrangements allow nucleic acid discrimination by type I-D Cascade,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","short":"E.A. Schwartz, T.M. McBride, J.P.K. Bravo, D. Wrapp, P.C. Fineran, R.D. Fagerlund, D.W. Taylor, Nature Communications 13 (2022).","apa":"Schwartz, E. A., McBride, T. M., Bravo, J. P. K., Wrapp, D., Fineran, P. C., Fagerlund, R. D., &#38; Taylor, D. W. (2022). Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-30402-8\">https://doi.org/10.1038/s41467-022-30402-8</a>","mla":"Schwartz, Evan A., et al. “Structural Rearrangements Allow Nucleic Acid Discrimination by Type I-D Cascade.” <i>Nature Communications</i>, vol. 13, 2829, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-30402-8\">10.1038/s41467-022-30402-8</a>.","ista":"Schwartz EA, McBride TM, Bravo JPK, Wrapp D, Fineran PC, Fagerlund RD, Taylor DW. 2022. Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. Nature Communications. 13, 2829.","ama":"Schwartz EA, McBride TM, Bravo JPK, et al. Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-30402-8\">10.1038/s41467-022-30402-8</a>"},"article_processing_charge":"Yes","date_created":"2024-03-20T10:42:05Z","volume":13,"publisher":"Springer Nature","pmid":1,"status":"public","oa":1,"title":"Structural rearrangements allow nucleic acid discrimination by type I-D Cascade","intvolume":"        13","oa_version":"Published Version","year":"2022","author":[{"full_name":"Schwartz, Evan A.","last_name":"Schwartz","first_name":"Evan A."},{"last_name":"McBride","full_name":"McBride, Tess M.","first_name":"Tess M."},{"last_name":"Bravo","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","full_name":"Bravo, Jack Peter Kelly","first_name":"Jack Peter Kelly","orcid":"0000-0003-0456-0753"},{"last_name":"Wrapp","full_name":"Wrapp, Daniel","first_name":"Daniel"},{"first_name":"Peter C.","last_name":"Fineran","full_name":"Fineran, Peter C."},{"first_name":"Robert D.","full_name":"Fagerlund, Robert D.","last_name":"Fagerlund"},{"first_name":"David W.","full_name":"Taylor, David W.","last_name":"Taylor"}],"article_number":"2829","date_updated":"2024-06-04T06:14:28Z","month":"05","main_file_link":[{"url":"https://doi.org/10.1038/s41467-022-30402-8","open_access":"1"}],"extern":"1","date_published":"2022-05-20T00:00:00Z","abstract":[{"text":"CRISPR-Cas systems are adaptive immune systems that protect prokaryotes from foreign nucleic acids, such as bacteriophages. Two of the most prevalent CRISPR-Cas systems include type I and type III. Interestingly, the type I-D interference proteins contain characteristic features of both type I and type III systems. Here, we present the structures of type I-D Cascade bound to both a double-stranded (ds)DNA and a single-stranded (ss)RNA target at 2.9 and 3.1 Å, respectively. We show that type I-D Cascade is capable of specifically binding ssRNA and reveal how PAM recognition of dsDNA targets initiates long-range structural rearrangements that likely primes Cas10d for Cas3′ binding and subsequent non-target strand DNA cleavage. These structures allow us to model how binding of the anti-CRISPR protein AcrID1 likely blocks target dsDNA binding via competitive inhibition of the DNA substrate engagement with the Cas10d active site. This work elucidates the unique mechanisms used by type I-D Cascade for discrimination of single-stranded and double stranded targets. Thus, our data supports a model for the hybrid nature of this complex with features of type III and type I systems.","lang":"eng"}],"day":"20","fulldoi":"https://doi.org/10.1038/s41467-022-30402-8","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"publication_identifier":{"issn":["2041-1723"]},"publication":"Nature Communications","language":[{"iso":"eng"}],"publication_status":"published","quality_controlled":"1","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","doi":"10.1038/s41467-022-30402-8"},{"publication_identifier":{"eissn":["1520-5002"],"issn":["0897-4756"]},"project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","name":"International IST Doctoral Program","call_identifier":"H2020"}],"keyword":["Materials Chemistry","General Chemical Engineering","General Chemistry"],"fulldoi":"https://doi.org/10.1021/acs.chemmater.2c01967","ec_funded":1,"corr_author":"1","day":"20","abstract":[{"lang":"eng","text":"Thermoelectric technology requires synthesizing complex materials where not only the crystal structure but also other structural features such as defects, grain size and orientation, and interfaces must be controlled. To date, conventional solid-state techniques are unable to provide this level of control. Herein, we present a synthetic approach in which dense inorganic thermoelectric materials are produced by the consolidation of well-defined nanoparticle powders. The idea is that controlling the characteristics of the powder allows the chemical transformations that take place during consolidation to be guided, ultimately yielding inorganic solids with targeted features. Different from conventional methods, syntheses in solution can produce particles with unprecedented control over their size, shape, crystal structure, composition, and surface chemistry. However, to date, most works have focused only on the low-cost benefits of this strategy. In this perspective, we first cover the opportunities that solution processing of the powder offers, emphasizing the potential structural features that can be controlled by precisely engineering the inorganic core of the particle, the surface, and the organization of the particles before consolidation. We then discuss the challenges of this synthetic approach and more practical matters related to solution processing. Finally, we suggest some good practices for adequate knowledge transfer and improving reproducibility among different laboratories."}],"file":[{"file_id":"12434","access_level":"open_access","checksum":"f7143e44ab510519d1949099c3558532","date_created":"2023-01-30T07:35:09Z","date_updated":"2023-01-30T07:35:09Z","creator":"dernst","success":1,"content_type":"application/pdf","file_size":10923495,"file_name":"2022_ChemistryMaterials_Fiedler.pdf","relation":"main_file"}],"date_published":"2022-09-20T00:00:00Z","license":"https://creativecommons.org/licenses/by/4.0/","page":"8471-8489","scopus_import":"1","doi":"10.1021/acs.chemmater.2c01967","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_status":"published","type":"journal_article","quality_controlled":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"related_material":{"record":[{"status":"public","id":"20415","relation":"dissertation_contains"},{"status":"public","relation":"dissertation_contains","id":"12885"},{"status":"public","relation":"dissertation_contains","id":"22017"},{"relation":"dissertation_contains","id":"22626","status":"public"}]},"language":[{"iso":"eng"}],"publication":"Chemistry of Materials","oa":1,"intvolume":"        34","title":"Solution-processed inorganic thermoelectric materials: Opportunities and challenges ∇","status":"public","pmid":1,"file_date_updated":"2023-01-30T07:35:09Z","publisher":"American Chemical Society","citation":{"apa":"Fiedler, C., Kleinhanns, T., Garcia, M., Lee, S., Calcabrini, M., &#38; Ibáñez, M. (2022). Solution-processed inorganic thermoelectric materials: Opportunities and challenges ∇. <i>Chemistry of Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">https://doi.org/10.1021/acs.chemmater.2c01967</a>","short":"C. Fiedler, T. Kleinhanns, M. Garcia, S. Lee, M. Calcabrini, M. Ibáñez, Chemistry of Materials 34 (2022) 8471–8489.","ama":"Fiedler C, Kleinhanns T, Garcia M, Lee S, Calcabrini M, Ibáñez M. Solution-processed inorganic thermoelectric materials: Opportunities and challenges ∇. <i>Chemistry of Materials</i>. 2022;34(19):8471-8489. doi:<a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">10.1021/acs.chemmater.2c01967</a>","ista":"Fiedler C, Kleinhanns T, Garcia M, Lee S, Calcabrini M, Ibáñez M. 2022. Solution-processed inorganic thermoelectric materials: Opportunities and challenges ∇. Chemistry of Materials. 34(19), 8471–8489.","mla":"Fiedler, Christine, et al. “Solution-Processed Inorganic Thermoelectric Materials: Opportunities and Challenges ∇.” <i>Chemistry of Materials</i>, vol. 34, no. 19, American Chemical Society, 2022, pp. 8471–89, doi:<a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">10.1021/acs.chemmater.2c01967</a>.","chicago":"Fiedler, Christine, Tobias Kleinhanns, Maria Garcia, Seungho Lee, Mariano Calcabrini, and Maria Ibáñez. “Solution-Processed Inorganic Thermoelectric Materials: Opportunities and Challenges ∇.” <i>Chemistry of Materials</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">https://doi.org/10.1021/acs.chemmater.2c01967</a>.","ieee":"C. Fiedler, T. Kleinhanns, M. Garcia, S. Lee, M. Calcabrini, and M. Ibáñez, “Solution-processed inorganic thermoelectric materials: Opportunities and challenges ∇,” <i>Chemistry of Materials</i>, vol. 34, no. 19. American Chemical Society, pp. 8471–8489, 2022."},"volume":34,"article_processing_charge":"Yes (via OA deal)","date_created":"2023-01-16T09:51:26Z","external_id":{"pmid":["36248227"],"isi":["000917837600001"]},"_id":"12237","article_type":"original","issue":"19","has_accepted_license":"1","department":[{"_id":"MaIb"}],"isi":1,"month":"09","ddc":["540"],"date_updated":"2026-08-11T12:39:14Z","author":[{"first_name":"Christine","full_name":"Fiedler, Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366","last_name":"Fiedler"},{"full_name":"Kleinhanns, Tobias","last_name":"Kleinhanns","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425","orcid":"0000-0003-1537-7436","first_name":"Tobias"},{"first_name":"Maria","full_name":"Garcia, Maria","last_name":"Garcia","id":"6e5c50b8-97dc-11ed-be98-b0a74c84cae0"},{"first_name":"Seungho","orcid":"0000-0002-6962-8598","full_name":"Lee, Seungho","last_name":"Lee","id":"BB243B88-D767-11E9-B658-BC13E6697425"},{"last_name":"Calcabrini","id":"45D7531A-F248-11E8-B48F-1D18A9856A87","full_name":"Calcabrini, Mariano","orcid":"0000-0003-4566-5877","first_name":"Mariano"},{"first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87"}],"acknowledgement":"This work was financially supported by ISTA and the Werner Siemens Foundation. M.C. has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement no. 665385.","oa_version":"Published Version","year":"2022"},{"acknowledgement":"We acknowledge members of the Loose laboratory at IST Austria for helpful discussions—in particular L. Lindorfer for his assistance with cloning and purifications. We thank J. Löwe and T. Nierhaus (MRC-LMB Cambridge, UK) for sharing unpublished work and helpful discussions, as well as D. Vavylonis and D. Rutkowski (Lehigh University, Bethlehem, PA, USA) and S. Martin (University of Lausanne, Switzerland) for sharing their code for FRAP analysis. We are also thankful for the support by the Scientific Service Units (SSU) of IST Austria through resources provided by the Imaging and Optics Facility (IOF) and the Lab Support Facility (LSF). This work was supported by the European Research Council through grant ERC 2015-StG-679239 and by the Austrian Science Fund (FWF) StandAlone P34607 to M.L. and HFSP LT 000824/2016-L4 to N.B. For the purpose of open access, we have applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.","author":[{"full_name":"Radler, Philipp","last_name":"Radler","id":"40136C2A-F248-11E8-B48F-1D18A9856A87","first_name":"Philipp","orcid":"0000-0001-9198-2182 "},{"orcid":"0000-0002-3086-9124","first_name":"Natalia S.","full_name":"Baranova, Natalia S.","id":"38661662-F248-11E8-B48F-1D18A9856A87","last_name":"Baranova"},{"first_name":"Paulo R","orcid":"0000-0001-6730-4461","full_name":"Dos Santos Caldas, Paulo R","id":"38FCDB4C-F248-11E8-B48F-1D18A9856A87","last_name":"Dos Santos Caldas"},{"full_name":"Sommer, Christoph M","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","last_name":"Sommer","orcid":"0000-0003-1216-9105","first_name":"Christoph M"},{"first_name":"Maria D","id":"319AA9CE-F248-11E8-B48F-1D18A9856A87","last_name":"Lopez Pelegrin","full_name":"Lopez Pelegrin, Maria D"},{"first_name":"David","last_name":"Michalik","id":"B9577E20-AA38-11E9-AC9A-0930E6697425","full_name":"Michalik, David"},{"full_name":"Loose, Martin","id":"462D4284-F248-11E8-B48F-1D18A9856A87","last_name":"Loose","first_name":"Martin","orcid":"0000-0001-7309-9724"}],"oa_version":"Published Version","year":"2022","ddc":["570"],"date_updated":"2026-09-25T22:30:08Z","article_number":"2635","department":[{"_id":"MaLo"}],"month":"05","isi":1,"has_accepted_license":"1","external_id":{"isi":["000795171100037"]},"article_type":"original","_id":"11373","publisher":"Springer Nature","article_processing_charge":"No","volume":13,"citation":{"ista":"Radler P, Baranova NS, Dos Santos Caldas PR, Sommer CM, Lopez Pelegrin MD, Michalik D, Loose M. 2022. In vitro reconstitution of Escherichia coli divisome activation. Nature Communications. 13, 2635.","ama":"Radler P, Baranova NS, Dos Santos Caldas PR, et al. In vitro reconstitution of Escherichia coli divisome activation. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-30301-y\">10.1038/s41467-022-30301-y</a>","mla":"Radler, Philipp, et al. “In Vitro Reconstitution of Escherichia Coli Divisome Activation.” <i>Nature Communications</i>, vol. 13, 2635, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-30301-y\">10.1038/s41467-022-30301-y</a>.","apa":"Radler, P., Baranova, N. S., Dos Santos Caldas, P. R., Sommer, C. M., Lopez Pelegrin, M. D., Michalik, D., &#38; Loose, M. (2022). In vitro reconstitution of Escherichia coli divisome activation. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-30301-y\">https://doi.org/10.1038/s41467-022-30301-y</a>","short":"P. Radler, N.S. Baranova, P.R. Dos Santos Caldas, C.M. Sommer, M.D. Lopez Pelegrin, D. Michalik, M. Loose, Nature Communications 13 (2022).","ieee":"P. Radler <i>et al.</i>, “In vitro reconstitution of Escherichia coli divisome activation,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","chicago":"Radler, Philipp, Natalia S. Baranova, Paulo R Dos Santos Caldas, Christoph M Sommer, Maria D Lopez Pelegrin, David Michalik, and Martin Loose. “In Vitro Reconstitution of Escherichia Coli Divisome Activation.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-30301-y\">https://doi.org/10.1038/s41467-022-30301-y</a>."},"date_created":"2022-05-13T09:06:28Z","status":"public","file_date_updated":"2022-05-13T09:10:51Z","title":"In vitro reconstitution of Escherichia coli divisome activation","intvolume":"        13","oa":1,"publication":"Nature Communications","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1038/s41467-022-34485-1"}],"record":[{"status":"public","relation":"research_data","id":"10934"},{"relation":"dissertation_contains","id":"14280","status":"public"}]},"language":[{"iso":"eng"}],"quality_controlled":"1","type":"journal_article","publication_status":"published","doi":"10.1038/s41467-022-30301-y","scopus_import":"1","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","file":[{"date_created":"2022-05-13T09:10:51Z","date_updated":"2022-05-13T09:10:51Z","file_id":"11374","access_level":"open_access","checksum":"5af863ee1b95a0710f6ee864d68dc7a6","content_type":"application/pdf","file_size":6945191,"relation":"main_file","file_name":"2022_NatureCommunications_Radler.pdf","creator":"dernst","success":1}],"date_published":"2022-05-12T00:00:00Z","day":"12","abstract":[{"text":"The actin-homologue FtsA is essential for E. coli cell division, as it links FtsZ filaments in the Z-ring to transmembrane proteins. FtsA is thought to initiate cell constriction by switching from an inactive polymeric to an active monomeric conformation, which recruits downstream proteins and stabilizes the Z-ring. However, direct biochemical evidence for this mechanism is missing. Here, we use reconstitution experiments and quantitative fluorescence microscopy to study divisome activation in vitro. By comparing wild-type FtsA with FtsA R286W, we find that this hyperactive mutant outperforms FtsA WT in replicating FtsZ treadmilling dynamics, FtsZ filament stabilization and recruitment of FtsN. We could attribute these differences to a faster exchange and denser packing of FtsA R286W below FtsZ filaments. Using FRET microscopy, we also find that FtsN binding promotes FtsA self-interaction. We propose that in the active divisome FtsA and FtsN exist as a dynamic copolymer that follows treadmilling filaments of FtsZ.","lang":"eng"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"fulldoi":"https://doi.org/10.1038/s41467-022-30301-y","corr_author":"1","ec_funded":1,"publication_identifier":{"issn":["2041-1723"]},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry"],"project":[{"grant_number":"679239","name":"Self-Organization of the Bacterial Cell","call_identifier":"H2020","_id":"2595697A-B435-11E9-9278-68D0E5697425"},{"name":"In vitro reconstitution of bacterial cell division","grant_number":"P34607","_id":"fc38323b-9c52-11eb-aca3-ff8afb4a011d"}]},{"publisher":"Springer Nature","date_created":"2023-02-20T08:11:29Z","article_processing_charge":"No","volume":12,"citation":{"ama":"Miles E, McCarthy M, Dehecq A, Kneib M, Fugger S, Pellicciotti F. Health and sustainability of glaciers in High Mountain Asia. <i>Nature Communications</i>. 2021;12. doi:<a href=\"https://doi.org/10.1038/s41467-021-23073-4\">10.1038/s41467-021-23073-4</a>","ista":"Miles E, McCarthy M, Dehecq A, Kneib M, Fugger S, Pellicciotti F. 2021. Health and sustainability of glaciers in High Mountain Asia. Nature Communications. 12, 2868.","mla":"Miles, Evan, et al. “Health and Sustainability of Glaciers in High Mountain Asia.” <i>Nature Communications</i>, vol. 12, 2868, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23073-4\">10.1038/s41467-021-23073-4</a>.","short":"E. Miles, M. McCarthy, A. Dehecq, M. Kneib, S. Fugger, F. Pellicciotti, Nature Communications 12 (2021).","apa":"Miles, E., McCarthy, M., Dehecq, A., Kneib, M., Fugger, S., &#38; Pellicciotti, F. (2021). Health and sustainability of glaciers in High Mountain Asia. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-23073-4\">https://doi.org/10.1038/s41467-021-23073-4</a>","ieee":"E. Miles, M. McCarthy, A. Dehecq, M. Kneib, S. Fugger, and F. Pellicciotti, “Health and sustainability of glaciers in High Mountain Asia,” <i>Nature Communications</i>, vol. 12. Springer Nature, 2021.","chicago":"Miles, Evan, Michael McCarthy, Amaury Dehecq, Marin Kneib, Stefan Fugger, and Francesca Pellicciotti. “Health and Sustainability of Glaciers in High Mountain Asia.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23073-4\">https://doi.org/10.1038/s41467-021-23073-4</a>."},"article_type":"original","_id":"12585","intvolume":"        12","title":"Health and sustainability of glaciers in High Mountain Asia","oa":1,"status":"public","date_updated":"2023-02-28T13:21:51Z","article_number":"2868","author":[{"first_name":"Evan","full_name":"Miles, Evan","last_name":"Miles"},{"last_name":"McCarthy","full_name":"McCarthy, Michael","first_name":"Michael"},{"last_name":"Dehecq","full_name":"Dehecq, Amaury","first_name":"Amaury"},{"full_name":"Kneib, Marin","last_name":"Kneib","first_name":"Marin"},{"full_name":"Fugger, Stefan","last_name":"Fugger","first_name":"Stefan"},{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca"}],"oa_version":"Published Version","year":"2021","extern":"1","month":"05","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-021-23073-4"}],"day":"17","abstract":[{"lang":"eng","text":"Glaciers in High Mountain Asia generate meltwater that supports the water needs of 250 million people, but current knowledge of annual accumulation and ablation is limited to sparse field measurements biased in location and glacier size. Here, we present altitudinally-resolved specific mass balances (surface, internal, and basal combined) for 5527 glaciers in High Mountain Asia for 2000–2016, derived by correcting observed glacier thinning patterns for mass redistribution due to ice flow. We find that 41% of glaciers accumulated mass over less than 20% of their area, and only 60% ± 10% of regional annual ablation was compensated by accumulation. Even without 21st century warming, 21% ± 1% of ice volume will be lost by 2100 due to current climatic-geometric imbalance, representing a reduction in glacier ablation into rivers of 28% ± 1%. The ablation of glaciers in the Himalayas and Tien Shan was mostly unsustainable and ice volume in these regions will reduce by at least 30% by 2100. The most important and vulnerable glacier-fed river basins (Amu Darya, Indus, Syr Darya, Tarim Interior) were supplied with >50% sustainable glacier ablation but will see long-term reductions in ice mass and glacier meltwater supply regardless of the Karakoram Anomaly."}],"date_published":"2021-05-17T00:00:00Z","publication_identifier":{"issn":["2041-1723"]},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"fulldoi":"https://doi.org/10.1038/s41467-021-23073-4","language":[{"iso":"eng"}],"publication":"Nature Communications","doi":"10.1038/s41467-021-23073-4","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","quality_controlled":"1","publication_status":"published"},{"language":[{"iso":"eng"}],"publication":"Nature Chemistry","scopus_import":"1","doi":"10.1038/s41557-021-00752-9","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","quality_controlled":"1","type":"journal_article","day":"01","abstract":[{"lang":"eng","text":"Coulombic interactions can be used to assemble charged nanoparticles into higher-order structures, but the process requires oppositely charged partners that are similarly sized. The ability to mediate the assembly of such charged nanoparticles using structurally simple small molecules would greatly facilitate the fabrication of nanostructured materials and harnessing their applications in catalysis, sensing and photonics. Here we show that small molecules with as few as three electric charges can effectively induce attractive interactions between oppositely charged nanoparticles in water. These interactions can guide the assembly of charged nanoparticles into colloidal crystals of a quality previously only thought to result from their co-crystallization with oppositely charged nanoparticles of a similar size. Transient nanoparticle assemblies can be generated using positively charged nanoparticles and multiply charged anions that are enzymatically hydrolysed into mono- and/or dianions. Our findings demonstrate an approach for the facile fabrication, manipulation and further investigation of static and dynamic nanostructured materials in aqueous environments."}],"date_published":"2021-10-01T00:00:00Z","page":"940-949","publication_identifier":{"eissn":["1755-4349"],"issn":["1755-4330"]},"keyword":["General Chemical Engineering","General Chemistry"],"fulldoi":"https://doi.org/10.1038/s41557-021-00752-9","date_updated":"2024-10-14T12:11:57Z","author":[{"last_name":"Bian","full_name":"Bian, Tong","first_name":"Tong"},{"last_name":"Gardin","full_name":"Gardin, Andrea","first_name":"Andrea"},{"full_name":"Gemen, Julius","last_name":"Gemen","first_name":"Julius"},{"last_name":"Houben","full_name":"Houben, Lothar","first_name":"Lothar"},{"first_name":"Claudio","full_name":"Perego, Claudio","last_name":"Perego"},{"first_name":"Byeongdu","last_name":"Lee","full_name":"Lee, Byeongdu"},{"first_name":"Nadav","full_name":"Elad, Nadav","last_name":"Elad"},{"first_name":"Zonglin","last_name":"Chu","full_name":"Chu, Zonglin"},{"last_name":"Pavan","full_name":"Pavan, Giovanni M.","first_name":"Giovanni M."},{"first_name":"Rafal","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn","full_name":"Klajn, Rafal"}],"oa_version":"Published Version","year":"2021","issue":"10","extern":"1","month":"10","main_file_link":[{"url":"https://doi.org/10.1038/s41557-021-00752-9","open_access":"1"}],"publisher":"Springer Nature","volume":13,"article_processing_charge":"No","date_created":"2023-08-01T09:34:54Z","citation":{"ieee":"T. Bian <i>et al.</i>, “Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures,” <i>Nature Chemistry</i>, vol. 13, no. 10. Springer Nature, pp. 940–949, 2021.","chicago":"Bian, Tong, Andrea Gardin, Julius Gemen, Lothar Houben, Claudio Perego, Byeongdu Lee, Nadav Elad, Zonglin Chu, Giovanni M. Pavan, and Rafal Klajn. “Electrostatic Co-Assembly of Nanoparticles with Oppositely Charged Small Molecules into Static and Dynamic Superstructures.” <i>Nature Chemistry</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41557-021-00752-9\">https://doi.org/10.1038/s41557-021-00752-9</a>.","ista":"Bian T, Gardin A, Gemen J, Houben L, Perego C, Lee B, Elad N, Chu Z, Pavan GM, Klajn R. 2021. Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures. Nature Chemistry. 13(10), 940–949.","ama":"Bian T, Gardin A, Gemen J, et al. Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures. <i>Nature Chemistry</i>. 2021;13(10):940-949. doi:<a href=\"https://doi.org/10.1038/s41557-021-00752-9\">10.1038/s41557-021-00752-9</a>","mla":"Bian, Tong, et al. “Electrostatic Co-Assembly of Nanoparticles with Oppositely Charged Small Molecules into Static and Dynamic Superstructures.” <i>Nature Chemistry</i>, vol. 13, no. 10, Springer Nature, 2021, pp. 940–49, doi:<a href=\"https://doi.org/10.1038/s41557-021-00752-9\">10.1038/s41557-021-00752-9</a>.","short":"T. Bian, A. Gardin, J. Gemen, L. Houben, C. Perego, B. Lee, N. Elad, Z. Chu, G.M. Pavan, R. Klajn, Nature Chemistry 13 (2021) 940–949.","apa":"Bian, T., Gardin, A., Gemen, J., Houben, L., Perego, C., Lee, B., … Klajn, R. (2021). Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures. <i>Nature Chemistry</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41557-021-00752-9\">https://doi.org/10.1038/s41557-021-00752-9</a>"},"external_id":{"pmid":["34489564"]},"_id":"13357","article_type":"original","oa":1,"title":"Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures","intvolume":"        13","status":"public","pmid":1},{"fulldoi":"https://doi.org/10.1002/anie.202014963","publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"keyword":["General Chemistry","Catalysis"],"date_published":"2021-03-08T00:00:00Z","page":"5859-5863","day":"08","abstract":[{"text":"DNA nanotechnology offers a versatile toolbox for precise spatial and temporal manipulation of matter on the nanoscale. However, rendering DNA-based systems responsive to light has remained challenging. Herein, we describe the remote manipulation of native (non-photoresponsive) chiral plasmonic molecules (CPMs) using light. Our strategy is based on the use of a photoresponsive medium comprising a merocyanine-based photoacid. Upon exposure to visible light, the medium decreases its pH, inducing the formation of DNA triplex links, leading to a spatial reconfiguration of the CPMs. The process can be reversed simply by turning the light off and it can be repeated for multiple cycles. The degree of the overall chirality change in an ensemble of CPMs depends on the CPM fraction undergoing reconfiguration, which, remarkably, depends on and can be tuned by the intensity of incident light. Such a dynamic, remotely controlled system could aid in further advancing DNA-based devices and nanomaterials.","lang":"eng"}],"quality_controlled":"1","type":"journal_article","publication_status":"published","doi":"10.1002/anie.202014963","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Angewandte Chemie International Edition","language":[{"iso":"eng"}],"related_material":{"link":[{"url":"https://doi.org/10.1002/anie.202210394","relation":"erratum"}]},"status":"public","intvolume":"        60","title":"Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies","oa":1,"article_type":"original","_id":"13358","publisher":"Wiley","article_processing_charge":"No","volume":60,"date_created":"2023-08-01T09:35:06Z","citation":{"ista":"Ryssy J, Natarajan AK, Wang J, Lehtonen AJ, Nguyen M, Klajn R, Kuzyk A. 2021. Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies. Angewandte Chemie International Edition. 60(11), 5859–5863.","mla":"Ryssy, Joonas, et al. “Light‐responsive Dynamic DNA‐origami‐based Plasmonic Assemblies.” <i>Angewandte Chemie International Edition</i>, vol. 60, no. 11, Wiley, 2021, pp. 5859–63, doi:<a href=\"https://doi.org/10.1002/anie.202014963\">10.1002/anie.202014963</a>.","ama":"Ryssy J, Natarajan AK, Wang J, et al. Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies. <i>Angewandte Chemie International Edition</i>. 2021;60(11):5859-5863. doi:<a href=\"https://doi.org/10.1002/anie.202014963\">10.1002/anie.202014963</a>","apa":"Ryssy, J., Natarajan, A. K., Wang, J., Lehtonen, A. J., Nguyen, M., Klajn, R., &#38; Kuzyk, A. (2021). Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202014963\">https://doi.org/10.1002/anie.202014963</a>","short":"J. Ryssy, A.K. Natarajan, J. Wang, A.J. Lehtonen, M. Nguyen, R. Klajn, A. Kuzyk, Angewandte Chemie International Edition 60 (2021) 5859–5863.","ieee":"J. Ryssy <i>et al.</i>, “Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies,” <i>Angewandte Chemie International Edition</i>, vol. 60, no. 11. Wiley, pp. 5859–5863, 2021.","chicago":"Ryssy, Joonas, Ashwin K. Natarajan, Jinhua Wang, Arttu J. Lehtonen, Minh‐Kha Nguyen, Rafal Klajn, and Anton Kuzyk. “Light‐responsive Dynamic DNA‐origami‐based Plasmonic Assemblies.” <i>Angewandte Chemie International Edition</i>. Wiley, 2021. <a href=\"https://doi.org/10.1002/anie.202014963\">https://doi.org/10.1002/anie.202014963</a>."},"extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1002/anie.202014963"}],"month":"03","issue":"11","author":[{"last_name":"Ryssy","full_name":"Ryssy, Joonas","first_name":"Joonas"},{"full_name":"Natarajan, Ashwin K.","last_name":"Natarajan","first_name":"Ashwin K."},{"first_name":"Jinhua","full_name":"Wang, Jinhua","last_name":"Wang"},{"last_name":"Lehtonen","full_name":"Lehtonen, Arttu J.","first_name":"Arttu J."},{"first_name":"Minh‐Kha","full_name":"Nguyen, Minh‐Kha","last_name":"Nguyen"},{"id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn","full_name":"Klajn, Rafal","first_name":"Rafal"},{"first_name":"Anton","last_name":"Kuzyk","full_name":"Kuzyk, Anton"}],"oa_version":"Published Version","year":"2021","date_updated":"2023-08-02T07:22:23Z"},{"publication_identifier":{"issn":["2451-9294"]},"keyword":["Materials Chemistry","Biochemistry (medical)","General Chemical Engineering","Environmental Chemistry","Biochemistry","General Chemistry"],"fulldoi":"https://doi.org/10.1016/j.chempr.2020.11.025","day":"14","abstract":[{"text":"Dissipative self-assembly is ubiquitous in nature, where it gives rise to complex structures and functions such as self-healing, homeostasis, and camouflage. These phenomena are enabled by the continuous conversion of energy stored in chemical fuels, such as ATP. Over the past decade, an increasing number of synthetic chemically driven systems have been reported that mimic the features of their natural counterparts. At the same time, it has been shown that dissipative self-assembly can also be fueled by light; these optically fueled systems have been developed in parallel to the chemically fueled ones. In this perspective, we critically compare these two classes of systems. Despite the complementarity and fundamental differences between these two modes of dissipative self-assembly, our analysis reveals that multiple analogies exist between chemically and light-fueled systems. We hope that these considerations will facilitate further development of the field of dissipative self-assembly.","lang":"eng"}],"date_published":"2021-01-14T00:00:00Z","page":"23-37","doi":"10.1016/j.chempr.2020.11.025","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","type":"journal_article","publication_status":"published","language":[{"iso":"eng"}],"publication":"Chem","title":"Dissipative self-assembly: Fueling with chemicals versus light","intvolume":"         7","oa":1,"status":"public","publisher":"Elsevier","citation":{"mla":"Weißenfels, Maren, et al. “Dissipative Self-Assembly: Fueling with Chemicals versus Light.” <i>Chem</i>, vol. 7, no. 1, Elsevier, 2021, pp. 23–37, doi:<a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">10.1016/j.chempr.2020.11.025</a>.","ista":"Weißenfels M, Gemen J, Klajn R. 2021. Dissipative self-assembly: Fueling with chemicals versus light. Chem. 7(1), 23–37.","ama":"Weißenfels M, Gemen J, Klajn R. Dissipative self-assembly: Fueling with chemicals versus light. <i>Chem</i>. 2021;7(1):23-37. doi:<a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">10.1016/j.chempr.2020.11.025</a>","short":"M. Weißenfels, J. Gemen, R. Klajn, Chem 7 (2021) 23–37.","apa":"Weißenfels, M., Gemen, J., &#38; Klajn, R. (2021). Dissipative self-assembly: Fueling with chemicals versus light. <i>Chem</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">https://doi.org/10.1016/j.chempr.2020.11.025</a>","ieee":"M. Weißenfels, J. Gemen, and R. Klajn, “Dissipative self-assembly: Fueling with chemicals versus light,” <i>Chem</i>, vol. 7, no. 1. Elsevier, pp. 23–37, 2021.","chicago":"Weißenfels, Maren, Julius Gemen, and Rafal Klajn. “Dissipative Self-Assembly: Fueling with Chemicals versus Light.” <i>Chem</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">https://doi.org/10.1016/j.chempr.2020.11.025</a>."},"date_created":"2023-08-01T09:35:19Z","article_processing_charge":"No","volume":7,"article_type":"original","_id":"13359","issue":"1","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.chempr.2020.11.025"}],"month":"01","date_updated":"2024-10-14T12:12:18Z","author":[{"last_name":"Weißenfels","full_name":"Weißenfels, Maren","first_name":"Maren"},{"full_name":"Gemen, Julius","last_name":"Gemen","first_name":"Julius"},{"full_name":"Klajn, Rafal","last_name":"Klajn","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","first_name":"Rafal"}],"oa_version":"Published Version","year":"2021"},{"page":"8970-8978","date_published":"2021-10-22T00:00:00Z","abstract":[{"text":"We report the observation of an anomalous nonlinear optical response of the prototypical three-dimensional topological insulator bismuth selenide through the process of high-order harmonic generation. We find that the generation efficiency increases as the laser polarization is changed from linear to elliptical, and it becomes maximum for circular polarization. With the aid of a microscopic theory and a detailed analysis of the measured spectra, we reveal that such anomalous enhancement encodes the characteristic topology of the band structure that originates from the interplay of strong spin–orbit coupling and time-reversal symmetry protection. The implications are in ultrafast probing of topological phase transitions, light-field driven dissipationless electronics, and quantum computation.","lang":"eng"}],"day":"22","fulldoi":"https://doi.org/10.1021/acs.nanolett.1c02145","keyword":["Mechanical Engineering","Condensed Matter Physics","General Materials Science","General Chemistry","Bioengineering"],"publication_identifier":{"issn":["1530-6984"],"eissn":["1530-6992"]},"publication":"Nano Letters","language":[{"iso":"eng"}],"publication_status":"published","type":"journal_article","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","doi":"10.1021/acs.nanolett.1c02145","_id":"13996","article_type":"original","external_id":{"arxiv":["2109.15291"],"pmid":["34676752"]},"citation":{"apa":"Baykusheva, D. R., Chacón, A., Lu, J., Bailey, T. P., Sobota, J. A., Soifer, H., … Ghimire, S. (2021). All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">https://doi.org/10.1021/acs.nanolett.1c02145</a>","short":"D.R. Baykusheva, A. Chacón, J. Lu, T.P. Bailey, J.A. Sobota, H. Soifer, P.S. Kirchmann, C. Rotundu, C. Uher, T.F. Heinz, D.A. Reis, S. Ghimire, Nano Letters 21 (2021) 8970–8978.","ama":"Baykusheva DR, Chacón A, Lu J, et al. All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields. <i>Nano Letters</i>. 2021;21(21):8970-8978. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">10.1021/acs.nanolett.1c02145</a>","mla":"Baykusheva, Denitsa Rangelova, et al. “All-Optical Probe of Three-Dimensional Topological Insulators Based on High-Harmonic Generation by Circularly Polarized Laser Fields.” <i>Nano Letters</i>, vol. 21, no. 21, American Chemical Society, 2021, pp. 8970–78, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">10.1021/acs.nanolett.1c02145</a>.","ista":"Baykusheva DR, Chacón A, Lu J, Bailey TP, Sobota JA, Soifer H, Kirchmann PS, Rotundu C, Uher C, Heinz TF, Reis DA, Ghimire S. 2021. All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields. Nano Letters. 21(21), 8970–8978.","chicago":"Baykusheva, Denitsa Rangelova, Alexis Chacón, Jian Lu, Trevor P. Bailey, Jonathan A. Sobota, Hadas Soifer, Patrick S. Kirchmann, et al. “All-Optical Probe of Three-Dimensional Topological Insulators Based on High-Harmonic Generation by Circularly Polarized Laser Fields.” <i>Nano Letters</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">https://doi.org/10.1021/acs.nanolett.1c02145</a>.","ieee":"D. R. Baykusheva <i>et al.</i>, “All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields,” <i>Nano Letters</i>, vol. 21, no. 21. American Chemical Society, pp. 8970–8978, 2021."},"article_processing_charge":"No","date_created":"2023-08-09T13:09:15Z","volume":21,"publisher":"American Chemical Society","pmid":1,"arxiv":1,"status":"public","oa":1,"intvolume":"        21","title":"All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields","year":"2021","oa_version":"Published Version","author":[{"id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva","full_name":"Baykusheva, Denitsa Rangelova","first_name":"Denitsa Rangelova"},{"full_name":"Chacón, Alexis","last_name":"Chacón","first_name":"Alexis"},{"first_name":"Jian","full_name":"Lu, Jian","last_name":"Lu"},{"full_name":"Bailey, Trevor P.","last_name":"Bailey","first_name":"Trevor P."},{"first_name":"Jonathan A.","full_name":"Sobota, Jonathan A.","last_name":"Sobota"},{"first_name":"Hadas","full_name":"Soifer, Hadas","last_name":"Soifer"},{"first_name":"Patrick S.","full_name":"Kirchmann, Patrick S.","last_name":"Kirchmann"},{"first_name":"Costel","full_name":"Rotundu, Costel","last_name":"Rotundu"},{"first_name":"Ctirad","last_name":"Uher","full_name":"Uher, Ctirad"},{"first_name":"Tony F.","last_name":"Heinz","full_name":"Heinz, Tony F."},{"full_name":"Reis, David A.","last_name":"Reis","first_name":"David A."},{"full_name":"Ghimire, Shambhu","last_name":"Ghimire","first_name":"Shambhu"}],"date_updated":"2024-10-14T12:26:13Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1021/acs.nanolett.1c02145"}],"month":"10","extern":"1","issue":"21"},{"author":[{"first_name":"Jurre A.","last_name":"Steens","full_name":"Steens, Jurre A."},{"first_name":"Yifan","full_name":"Zhu, Yifan","last_name":"Zhu"},{"full_name":"Taylor, David W.","last_name":"Taylor","first_name":"David W."},{"orcid":"0000-0003-0456-0753","first_name":"Jack Peter Kelly","full_name":"Bravo, Jack Peter Kelly","last_name":"Bravo","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e"},{"first_name":"Stijn H. P.","last_name":"Prinsen","full_name":"Prinsen, Stijn H. P."},{"last_name":"Schoen","full_name":"Schoen, Cor D.","first_name":"Cor D."},{"full_name":"Keijser, Bart J. F.","last_name":"Keijser","first_name":"Bart J. F."},{"full_name":"Ossendrijver, Michel","last_name":"Ossendrijver","first_name":"Michel"},{"first_name":"L. Marije","full_name":"Hofstra, L. Marije","last_name":"Hofstra"},{"full_name":"Brouns, Stan J. J.","last_name":"Brouns","first_name":"Stan J. J."},{"first_name":"Akeo","full_name":"Shinkai, Akeo","last_name":"Shinkai"},{"full_name":"van der Oost, John","last_name":"van der Oost","first_name":"John"},{"first_name":"Raymond H. J.","last_name":"Staals","full_name":"Staals, Raymond H. J."}],"year":"2021","oa_version":"Published Version","article_number":"5033","date_updated":"2024-06-04T06:11:54Z","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-021-25337-5"}],"month":"08","external_id":{"pmid":["34413302"]},"_id":"15137","article_type":"original","publisher":"Springer Nature","volume":12,"article_processing_charge":"Yes","date_created":"2024-03-20T10:42:33Z","citation":{"mla":"Steens, Jurre A., et al. “SCOPE Enables Type III CRISPR-Cas Diagnostics Using Flexible Targeting and Stringent CARF Ribonuclease Activation.” <i>Nature Communications</i>, vol. 12, 5033, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-25337-5\">10.1038/s41467-021-25337-5</a>.","ama":"Steens JA, Zhu Y, Taylor DW, et al. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. <i>Nature Communications</i>. 2021;12. doi:<a href=\"https://doi.org/10.1038/s41467-021-25337-5\">10.1038/s41467-021-25337-5</a>","ista":"Steens JA, Zhu Y, Taylor DW, Bravo JPK, Prinsen SHP, Schoen CD, Keijser BJF, Ossendrijver M, Hofstra LM, Brouns SJJ, Shinkai A, van der Oost J, Staals RHJ. 2021. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. Nature Communications. 12, 5033.","apa":"Steens, J. A., Zhu, Y., Taylor, D. W., Bravo, J. P. K., Prinsen, S. H. P., Schoen, C. D., … Staals, R. H. J. (2021). SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-25337-5\">https://doi.org/10.1038/s41467-021-25337-5</a>","short":"J.A. Steens, Y. Zhu, D.W. Taylor, J.P.K. Bravo, S.H.P. Prinsen, C.D. Schoen, B.J.F. Keijser, M. Ossendrijver, L.M. Hofstra, S.J.J. Brouns, A. Shinkai, J. van der Oost, R.H.J. Staals, Nature Communications 12 (2021).","ieee":"J. A. Steens <i>et al.</i>, “SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation,” <i>Nature Communications</i>, vol. 12. Springer Nature, 2021.","chicago":"Steens, Jurre A., Yifan Zhu, David W. Taylor, Jack Peter Kelly Bravo, Stijn H. P. Prinsen, Cor D. Schoen, Bart J. F. Keijser, et al. “SCOPE Enables Type III CRISPR-Cas Diagnostics Using Flexible Targeting and Stringent CARF Ribonuclease Activation.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-25337-5\">https://doi.org/10.1038/s41467-021-25337-5</a>."},"status":"public","pmid":1,"oa":1,"title":"SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation","intvolume":"        12","publication":"Nature Communications","language":[{"iso":"eng"}],"publication_status":"published","type":"journal_article","quality_controlled":"1","scopus_import":"1","doi":"10.1038/s41467-021-25337-5","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2021-08-19T00:00:00Z","day":"19","abstract":[{"lang":"eng","text":"Characteristic properties of type III CRISPR-Cas systems include recognition of target RNA and the subsequent induction of a multifaceted immune response. This involves sequence-specific cleavage of the target RNA and production of cyclic oligoadenylate (cOA) molecules. Here we report that an exposed seed region at the 3′ end of the crRNA is essential for target RNA binding and cleavage, whereas cOA production requires base pairing at the 5′ end of the crRNA. Moreover, we uncover that the variation in the size and composition of type III complexes within a single host results in variable seed regions. This may prevent escape by invading genetic elements, while controlling cOA production tightly to prevent unnecessary damage to the host. Lastly, we use these findings to develop a new diagnostic tool, SCOPE, for the specific detection of SARS-CoV-2 from human nasal swab samples, revealing sensitivities in the atto-molar range."}],"fulldoi":"https://doi.org/10.1038/s41467-021-25337-5","publication_identifier":{"issn":["2041-1723"]},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"]},{"_id":"15260","article_type":"original","publisher":"American Chemical Society","volume":33,"date_created":"2024-04-03T07:23:30Z","citation":{"ista":"Cimada daSilva J, Balazs D, Dunbar TA, Hanrath T. 2021. Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface. Chemistry of Materials. 33(24), 9457–9472.","ama":"Cimada daSilva J, Balazs D, Dunbar TA, Hanrath T. Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface. <i>Chemistry of Materials</i>. 2021;33(24):9457-9472. doi:<a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">10.1021/acs.chemmater.1c02910</a>","mla":"Cimada daSilva, Jessica, et al. “Fundamental Processes and Practical Considerations of Lead Chalcogenide Mesocrystals Formed via Self-Assembly and Directed Attachment of Nanocrystals at a Fluid Interface.” <i>Chemistry of Materials</i>, vol. 33, no. 24, American Chemical Society, 2021, pp. 9457–72, doi:<a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">10.1021/acs.chemmater.1c02910</a>.","apa":"Cimada daSilva, J., Balazs, D., Dunbar, T. A., &#38; Hanrath, T. (2021). Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface. <i>Chemistry of Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">https://doi.org/10.1021/acs.chemmater.1c02910</a>","short":"J. Cimada daSilva, D. Balazs, T.A. Dunbar, T. Hanrath, Chemistry of Materials 33 (2021) 9457–9472.","ieee":"J. Cimada daSilva, D. Balazs, T. A. Dunbar, and T. Hanrath, “Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface,” <i>Chemistry of Materials</i>, vol. 33, no. 24. American Chemical Society, pp. 9457–9472, 2021.","chicago":"Cimada daSilva, Jessica, Daniel Balazs, Tyler A. Dunbar, and Tobias Hanrath. “Fundamental Processes and Practical Considerations of Lead Chalcogenide Mesocrystals Formed via Self-Assembly and Directed Attachment of Nanocrystals at a Fluid Interface.” <i>Chemistry of Materials</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">https://doi.org/10.1021/acs.chemmater.1c02910</a>."},"article_processing_charge":"No","status":"public","oa":1,"title":"Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface","intvolume":"        33","author":[{"full_name":"Cimada daSilva, Jessica","last_name":"Cimada daSilva","first_name":"Jessica"},{"first_name":"Daniel","orcid":"0000-0001-7597-043X","last_name":"Balazs","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","full_name":"Balazs, Daniel"},{"last_name":"Dunbar","full_name":"Dunbar, Tyler A.","first_name":"Tyler A."},{"first_name":"Tobias","last_name":"Hanrath","full_name":"Hanrath, Tobias"}],"year":"2021","oa_version":"Submitted Version","date_updated":"2024-04-03T13:50:53Z","department":[{"_id":"LifeSc"}],"main_file_link":[{"url":"https://www.osti.gov/servlets/purl/1836502","open_access":"1"}],"month":"12","issue":"24","date_published":"2021-12-16T00:00:00Z","page":"9457-9472","day":"16","abstract":[{"text":"Significant advances in the synthesis and processing of colloidal nanocrystals have given scientists and engineers access to a vast library of building blocks with precisely defined size, shape, and composition. These materials have inspired exciting prospects to enable bottom-up fabrication of programmable materials with properties by design. Successfully assembling and connecting the building blocks into superstructures in which constituent nanocrystals can purposefully interact requires robust understanding of and control over a complex interplay of dynamic physicochemical processes. Fluid interfaces provide an advantageous experimental workbench to both probe and control these processes. Despite the ostensible simplicity of fabricating nanocrystal assemblies at a fluid interface, sensitivity to processing conditions and limited reproducibility have underscored the complexity of this process. In situ studies have provided mechanistic insights into the competing dynamics of key subprocesses including solvent spreading and evaporation, superlattice formation, ligand detachment kinetics, and nanocrystal attachment. Understanding how these subprocesses influence the complex choreography of self-assembly, structure transformation, and oriented attachment processes presents a rich research challenge. In this context, we present a detailed methodology for self-assembly and attachment of lead chalcogenide nanocrystals at a liquid–gas interface as a model system for the fabrication of mono- and multilayer cubic connected superlattices. We discuss key experimental parameters such as the characteristics of the building blocks and processing conditions and detailed steps from colloidal nanocrystal injection to superlattice transfer. We hope that this Methods/Protocols paper will provide guidance for future advances in the exciting path toward bringing the prospect of nanocrystal-based programmable materials to fruition.","lang":"eng"}],"fulldoi":"https://doi.org/10.1021/acs.chemmater.1c02910","publication_identifier":{"issn":["0897-4756"],"eissn":["1520-5002"]},"keyword":["Materials Chemistry","General Chemical Engineering","General Chemistry"],"publication":"Chemistry of Materials","language":[{"iso":"eng"}],"publication_status":"published","type":"journal_article","quality_controlled":"1","scopus_import":"1","doi":"10.1021/acs.chemmater.1c02910","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"keyword":["general physics and astronomy","general biochemistry","genetics and molecular biology","general chemistry"],"publication_identifier":{"eissn":["2041-1723"]},"fulldoi":"https://doi.org/10.1038/s41467-021-26360-2","abstract":[{"text":"The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a regulatory hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) as a regulator of transcription and mRNA stability that docks onto Pol II CTD through its SPOC domain. We characterize SPOC as a CTD reader domain that preferentially binds two phosphorylated Serine-2 marks in adjacent CTD repeats. PHF3 drives liquid-liquid phase separation of phosphorylated Pol II, colocalizes with Pol II clusters and tracks with Pol II across the length of genes. PHF3 knock-out or SPOC deletion in human cells results in increased Pol II stalling, reduced elongation rate and an increase in mRNA stability, with marked derepression of neuronal genes. Key neuronal genes are aberrantly expressed in Phf3 knock-out mouse embryonic stem cells, resulting in impaired neuronal differentiation. Our data suggest that PHF3 acts as a prominent effector of neuronal gene regulation by bridging transcription with mRNA decay.","lang":"eng"}],"day":"19","file":[{"date_created":"2021-10-21T13:51:49Z","date_updated":"2021-10-21T13:51:49Z","checksum":"d99fcd51aebde19c21314e3de0148007","file_id":"10169","access_level":"open_access","relation":"main_file","file_name":"2021_NatComm_Appel.pdf","content_type":"application/pdf","file_size":5111706,"success":1,"creator":"cchlebak"}],"date_published":"2021-10-19T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","scopus_import":"1","doi":"10.1038/s41467-021-26360-2","publication_status":"published","quality_controlled":"1","type":"journal_article","related_material":{"link":[{"relation":"earlier_version","description":"Preprint ","url":"https://www.biorxiv.org/content/10.1101/2020.02.11.943159"}]},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"publication":"Nature Communications","oa":1,"intvolume":"        12","title":"PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC","file_date_updated":"2021-10-21T13:51:49Z","status":"public","date_created":"2021-10-20T14:40:32Z","volume":12,"citation":{"chicago":"Appel, Lisa-Marie, Vedran Franke, Melania Bruno, Irina Grishkovskaya, Aiste Kasiliauskaite, Tanja Kaufmann, Ursula E. Schoeberl, et al. “PHF3 Regulates Neuronal Gene Expression through the Pol II CTD Reader Domain SPOC.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-26360-2\">https://doi.org/10.1038/s41467-021-26360-2</a>.","ieee":"L.-M. Appel <i>et al.</i>, “PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC,” <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.","short":"L.-M. Appel, V. Franke, M. Bruno, I. Grishkovskaya, A. Kasiliauskaite, T. Kaufmann, U.E. Schoeberl, M.G. Puchinger, S. Kostrhon, C. Ebenwaldner, M. Sebesta, E. Beltzung, K. Mechtler, G. Lin, A. Vlasova, M. Leeb, R. Pavri, A. Stark, A. Akalin, R. Stefl, C. Bernecky, K. Djinovic-Carugo, D. Slade, Nature Communications 12 (2021).","apa":"Appel, L.-M., Franke, V., Bruno, M., Grishkovskaya, I., Kasiliauskaite, A., Kaufmann, T., … Slade, D. (2021). PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-26360-2\">https://doi.org/10.1038/s41467-021-26360-2</a>","ama":"Appel L-M, Franke V, Bruno M, et al. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-26360-2\">10.1038/s41467-021-26360-2</a>","ista":"Appel L-M, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. 2021. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. Nature Communications. 12(1), 6078.","mla":"Appel, Lisa-Marie, et al. “PHF3 Regulates Neuronal Gene Expression through the Pol II CTD Reader Domain SPOC.” <i>Nature Communications</i>, vol. 12, no. 1, 6078, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-26360-2\">10.1038/s41467-021-26360-2</a>."},"article_processing_charge":"No","publisher":"Springer Nature","_id":"10163","article_type":"original","external_id":{"isi":["000709050300001"]},"has_accepted_license":"1","issue":"1","isi":1,"month":"10","department":[{"_id":"CaBe"}],"article_number":"6078","date_updated":"2024-10-21T06:02:05Z","ddc":["610"],"oa_version":"Published Version","year":"2021","author":[{"last_name":"Appel","full_name":"Appel, Lisa-Marie","first_name":"Lisa-Marie"},{"full_name":"Franke, Vedran","last_name":"Franke","first_name":"Vedran"},{"full_name":"Bruno, Melania","last_name":"Bruno","first_name":"Melania"},{"full_name":"Grishkovskaya, Irina","last_name":"Grishkovskaya","first_name":"Irina"},{"first_name":"Aiste","full_name":"Kasiliauskaite, Aiste","last_name":"Kasiliauskaite"},{"first_name":"Tanja","full_name":"Kaufmann, Tanja","last_name":"Kaufmann"},{"first_name":"Ursula E.","full_name":"Schoeberl, Ursula E.","last_name":"Schoeberl"},{"last_name":"Puchinger","full_name":"Puchinger, Martin G.","first_name":"Martin G."},{"full_name":"Kostrhon, Sebastian","last_name":"Kostrhon","first_name":"Sebastian"},{"first_name":"Carmen","last_name":"Ebenwaldner","full_name":"Ebenwaldner, Carmen"},{"last_name":"Sebesta","full_name":"Sebesta, Marek","first_name":"Marek"},{"first_name":"Etienne","full_name":"Beltzung, Etienne","last_name":"Beltzung"},{"full_name":"Mechtler, Karl","last_name":"Mechtler","first_name":"Karl"},{"first_name":"Gen","last_name":"Lin","full_name":"Lin, Gen"},{"full_name":"Vlasova, Anna","last_name":"Vlasova","first_name":"Anna"},{"last_name":"Leeb","full_name":"Leeb, Martin","first_name":"Martin"},{"last_name":"Pavri","full_name":"Pavri, Rushad","first_name":"Rushad"},{"first_name":"Alexander","last_name":"Stark","full_name":"Stark, Alexander"},{"first_name":"Altuna","last_name":"Akalin","full_name":"Akalin, Altuna"},{"last_name":"Stefl","full_name":"Stefl, Richard","first_name":"Richard"},{"full_name":"Bernecky, Carrie A","last_name":"Bernecky","id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0893-7036","first_name":"Carrie A"},{"first_name":"Kristina","full_name":"Djinovic-Carugo, Kristina","last_name":"Djinovic-Carugo"},{"first_name":"Dea","full_name":"Slade, Dea","last_name":"Slade"}],"acknowledgement":"D.S. thanks Claudine Kraft, Renée Schroeder, Verena Jantsch, Franz Klein and Peter Schlögelhofer for support. We thank Anita Testa Salmazo for help with purifying Pol II; Matthias Geyer and Robert Düster for sharing DYRK1A kinase; Felix Hartmann and Clemens Plaschka for help with mass photometry; Goran Kokic for design of the arrest assay sequences; Petra van der Lelij for help with generating mESC KO; Maximilian Freilinger for help with the purification of mEGFP-CTD; Stefan Ameres, Nina Fasching and Brian Reichholf for advice on SLAM-seq and for sharing reagents; Laura Gallego Valle for advice regarding LLPS assays; Krzysztof Chylinski for advice regarding CRISPR/Cas9 methodology; VBCF Protein Technologies facility for purifying PHF3 and providing gRNAs and Cas9; VBCF NGS facility for sequencing; Monoclonal antibody facility at the Helmholtz center for Pol II antibodies; Friedrich Propst and Elzbieta Kowalska for advice and for sharing materials; Egon Ogris for sharing materials; Martin Eilers for recommending a ChIP-grade TFIIS antibody; Susanne Opravil, Otto Hudecz, Markus Hartl and Natascha Hartl for mass spectrometry analysis; staff of the X-ray beamlines at the ESRF in Grenoble for their excellent support; Christa Bücker, Anton Meinhart, Clemens Plaschka and members of the Slade lab for critical comments on the manuscript; Life Science Editors for editing assistance. M.B. and D.S. acknowledge support by the FWF-funded DK ‘Chromosome Dynamics’. T.K. is a recipient of the DOC fellowship from the Austrian Academy of Sciences. U.S. is supported by the L’Oreal for Women in Science Austria Fellowship and the Austrian Science Fund (FWF T 795-B30). M.L is supported by the Vienna Science and Technology Fund (WWTF, VRG14-006). R.S. is supported by the Czech Science Foundation (15-17670 S and 21-24460 S), Ministry of Education, Youths and Sports of the Czech Republic (CEITEC 2020 project (LQ1601)), and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement no. 649030); this publication reflects only the author’s view and the Research Executive Agency is not responsible for any use that may be made of the information it contains. M.S. is supported by the Czech Science Foundation (GJ20-21581Y). K.D.C. research is supported by the Austrian Science Fund (FWF) Projects I525 and I1593, P22276, P19060, and W1221, Federal Ministry of Economy, Family and Youth through the initiative ‘Laura Bassi Centres of Expertise’, funding from the Centre of Optimized Structural Studies No. 253275, the Wellcome Trust Collaborative Award (201543/Z/16), COST action BM1405 Non-globular proteins - from sequence to structure, function and application in molecular physiopathology (NGP-NET), the Vienna Science and Technology Fund (WWTF LS17-008), and by the University of Vienna. This project was funded by the MFPL start-up grant, the Vienna Science and Technology Fund (WWTF LS14-001), and the Austrian Science Fund (P31546-B28 and W1258 “DK: Integrative Structural Biology”) to D.S."},{"acknowledgement":"We acknowledge support from the Royal Society (C. V. C. and A. Sˇ.), the Medical Research Council (C. V. C. and A. Sˇ.), and the European Research Council (Starting grant ‘‘NEPA’’ 802960 to A. Sˇ.). We thank Johannes Krausser and Ivan Palaia for fruitful discussions.","author":[{"first_name":"Christian","full_name":"Vanhille-Campos, Christian","last_name":"Vanhille-Campos"},{"last_name":"Šarić","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","full_name":"Šarić, Anđela","first_name":"Anđela","orcid":"0000-0002-7854-2139"}],"oa_version":"Published Version","year":"2021","date_updated":"2024-10-14T14:20:59Z","extern":"1","main_file_link":[{"open_access":"1","url":"https://pubs.rsc.org/en/content/articlehtml/2021/sm/d0sm02012e"}],"month":"02","issue":"14","OA_type":"hybrid","external_id":{"pmid":["33629089"]},"article_type":"original","_id":"10339","publisher":"Royal Society of Chemistry","article_processing_charge":"No","volume":17,"citation":{"mla":"Vanhille-Campos, Christian, and Anđela Šarić. “Modelling the Dynamics of Vesicle Reshaping and Scission under Osmotic Shocks.” <i>Soft Matter</i>, vol. 17, no. 14, Royal Society of Chemistry, 2021, pp. 3798–806, doi:<a href=\"https://doi.org/10.1039/d0sm02012e\">10.1039/d0sm02012e</a>.","ista":"Vanhille-Campos C, Šarić A. 2021. Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. Soft Matter. 17(14), 3798–3806.","ama":"Vanhille-Campos C, Šarić A. Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. <i>Soft Matter</i>. 2021;17(14):3798-3806. doi:<a href=\"https://doi.org/10.1039/d0sm02012e\">10.1039/d0sm02012e</a>","apa":"Vanhille-Campos, C., &#38; Šarić, A. (2021). Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. <i>Soft Matter</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d0sm02012e\">https://doi.org/10.1039/d0sm02012e</a>","short":"C. Vanhille-Campos, A. Šarić, Soft Matter 17 (2021) 3798–3806.","ieee":"C. Vanhille-Campos and A. Šarić, “Modelling the dynamics of vesicle reshaping and scission under osmotic shocks,” <i>Soft Matter</i>, vol. 17, no. 14. Royal Society of Chemistry, pp. 3798–3806, 2021.","chicago":"Vanhille-Campos, Christian, and Anđela Šarić. “Modelling the Dynamics of Vesicle Reshaping and Scission under Osmotic Shocks.” <i>Soft Matter</i>. Royal Society of Chemistry, 2021. <a href=\"https://doi.org/10.1039/d0sm02012e\">https://doi.org/10.1039/d0sm02012e</a>."},"date_created":"2021-11-25T16:06:42Z","status":"public","pmid":1,"title":"Modelling the dynamics of vesicle reshaping and scission under osmotic shocks","intvolume":"        17","oa":1,"publication":"Soft Matter","related_material":{"link":[{"relation":"earlier_version","url":"https://www.biorxiv.org/content/10.1101/2020.11.16.384602v2"}]},"tmp":{"short":"CC BY-NC (3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/3.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)"},"language":[{"iso":"eng"}],"type":"journal_article","quality_controlled":"1","publication_status":"published","doi":"10.1039/d0sm02012e","scopus_import":"1","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","date_published":"2021-02-16T00:00:00Z","page":"3798-3806","license":"https://creativecommons.org/licenses/by-nc/3.0/","day":"16","OA_place":"publisher","abstract":[{"text":"We study the effects of osmotic shocks on lipid vesicles via coarse-grained molecular dynamics simulations by explicitly considering the solute in the system. We find that depending on their nature (hypo- or hypertonic) such shocks can lead to bursting events or engulfing of external material into inner compartments, among other morphology transformations. We characterize the dynamics of these processes and observe a separation of time scales between the osmotic shock absorption and the shape relaxation. Our work consequently provides an insight into the dynamics of compartmentalization in vesicular systems as a result of osmotic shocks, which can be of interest in the context of early proto-cell development and proto-cell compartmentalisation.","lang":"eng"}],"fulldoi":"https://doi.org/10.1039/d0sm02012e","publication_identifier":{"eissn":["1744-6848"],"issn":["1744-683X"]},"keyword":["condensed matter physics","general chemistry"]},{"status":"public","arxiv":1,"intvolume":"         8","title":"Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3","oa":1,"external_id":{"arxiv":["2103.09029"]},"article_type":"original","_id":"9282","publisher":"IOP Publishing","citation":{"ista":"Nauman M, Kiem DH, Lee S, Son S, Park J-G, Kang W, Han MJ, Jo YJ. 2021. Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. 2D Materials. 8(3), 035011.","mla":"Nauman, Muhammad, et al. “Complete Mapping of Magnetic Anisotropy for Prototype Ising van Der Waals FePS3.” <i>2D Materials</i>, vol. 8, no. 3, 035011, IOP Publishing, 2021, doi:<a href=\"https://doi.org/10.1088/2053-1583/abeed3\">10.1088/2053-1583/abeed3</a>.","ama":"Nauman M, Kiem DH, Lee S, et al. Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. <i>2D Materials</i>. 2021;8(3). doi:<a href=\"https://doi.org/10.1088/2053-1583/abeed3\">10.1088/2053-1583/abeed3</a>","short":"M. Nauman, D.H. Kiem, S. Lee, S. Son, J.-G. Park, W. Kang, M.J. Han, Y.J. Jo, 2D Materials 8 (2021).","apa":"Nauman, M., Kiem, D. H., Lee, S., Son, S., Park, J.-G., Kang, W., … Jo, Y. J. (2021). Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. <i>2D Materials</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/2053-1583/abeed3\">https://doi.org/10.1088/2053-1583/abeed3</a>","ieee":"M. Nauman <i>et al.</i>, “Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3,” <i>2D Materials</i>, vol. 8, no. 3. IOP Publishing, 2021.","chicago":"Nauman, Muhammad, Do Hoon Kiem, Sungmin Lee, Suhan Son, J-G Park, Woun Kang, Myung Joon Han, and Youn Jung Jo. “Complete Mapping of Magnetic Anisotropy for Prototype Ising van Der Waals FePS3.” <i>2D Materials</i>. IOP Publishing, 2021. <a href=\"https://doi.org/10.1088/2053-1583/abeed3\">https://doi.org/10.1088/2053-1583/abeed3</a>."},"volume":8,"date_created":"2021-03-23T07:10:17Z","article_processing_charge":"No","extern":"1","department":[{"_id":"KiMo"}],"main_file_link":[{"url":"https://arxiv.org/abs/2103.09029","open_access":"1"}],"month":"04","issue":"3","author":[{"orcid":"0000-0002-2111-4846","first_name":"Muhammad","full_name":"Nauman, Muhammad","id":"32c21954-2022-11eb-9d5f-af9f93c24e71","last_name":"Nauman"},{"full_name":"Kiem, Do Hoon","last_name":"Kiem","first_name":"Do Hoon"},{"first_name":"Sungmin","full_name":"Lee, Sungmin","last_name":"Lee"},{"last_name":"Son","full_name":"Son, Suhan","first_name":"Suhan"},{"full_name":"Park, J-G","last_name":"Park","first_name":"J-G"},{"full_name":"Kang, Woun","last_name":"Kang","first_name":"Woun"},{"first_name":"Myung Joon","last_name":"Han","full_name":"Han, Myung Joon"},{"first_name":"Youn Jung","last_name":"Jo","full_name":"Jo, Youn Jung"}],"oa_version":"Preprint","year":"2021","date_updated":"2021-12-01T10:36:56Z","article_number":"035011","fulldoi":"https://doi.org/10.1088/2053-1583/abeed3","publication_identifier":{"issn":["2053-1583"]},"keyword":["Mechanical Engineering","General Materials Science","Mechanics of Materials","General Chemistry","Condensed Matter Physics"],"date_published":"2021-04-06T00:00:00Z","day":"06","abstract":[{"lang":"eng","text":"Several Ising-type magnetic van der Waals (vdW) materials exhibit stable magnetic ground states. Despite these clear experimental demonstrations, a complete theoretical and microscopic understanding of their magnetic anisotropy is still lacking. In particular, the validity limit of identifying their one-dimensional (1-D) Ising nature has remained uninvestigated in a quantitative way. Here we performed the complete mapping of magnetic anisotropy for a prototypical Ising vdW magnet FePS3 for the first time. Combining torque magnetometry measurements with their magnetostatic model analysis and the relativistic density functional total energy calculations, we successfully constructed the three-dimensional (3-D) mappings of the magnetic anisotropy in terms of magnetic torque and energy. The results not only quantitatively confirm that the easy axis is perpendicular to the ab plane, but also reveal the anisotropies within the ab, ac, and bc planes. Our approach can be applied to the detailed quantitative study of magnetism in vdW materials."}],"type":"journal_article","quality_controlled":"1","publication_status":"published","doi":"10.1088/2053-1583/abeed3","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publication":"2D Materials","language":[{"iso":"eng"}]},{"title":"Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer","intvolume":"        12","oa":1,"file_date_updated":"2021-06-09T15:21:14Z","status":"public","article_processing_charge":"No","volume":12,"citation":{"ieee":"M. Obr <i>et al.</i>, “Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer,” <i>Nature Communications</i>, vol. 12, no. 1. Nature Research, 2021.","chicago":"Obr, Martin, Clifton L. Ricana, Nadia Nikulin, Jon-Philip R. Feathers, Marco Klanschnig, Andreas Thader, Marc C. Johnson, Volker M. Vogt, Florian KM Schur, and Robert A. Dick. “Structure of the Mature Rous Sarcoma Virus Lattice Reveals a Role for IP6 in the Formation of the Capsid Hexamer.” <i>Nature Communications</i>. Nature Research, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23506-0\">https://doi.org/10.1038/s41467-021-23506-0</a>.","ista":"Obr M, Ricana CL, Nikulin N, Feathers J-PR, Klanschnig M, Thader A, Johnson MC, Vogt VM, Schur FK, Dick RA. 2021. Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nature Communications. 12(1), 3226.","ama":"Obr M, Ricana CL, Nikulin N, et al. Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23506-0\">10.1038/s41467-021-23506-0</a>","mla":"Obr, Martin, et al. “Structure of the Mature Rous Sarcoma Virus Lattice Reveals a Role for IP6 in the Formation of the Capsid Hexamer.” <i>Nature Communications</i>, vol. 12, no. 1, 3226, Nature Research, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23506-0\">10.1038/s41467-021-23506-0</a>.","short":"M. Obr, C.L. Ricana, N. Nikulin, J.-P.R. Feathers, M. Klanschnig, A. Thader, M.C. Johnson, V.M. Vogt, F.K. Schur, R.A. Dick, Nature Communications 12 (2021).","apa":"Obr, M., Ricana, C. L., Nikulin, N., Feathers, J.-P. R., Klanschnig, M., Thader, A., … Dick, R. A. (2021). Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. <i>Nature Communications</i>. Nature Research. <a href=\"https://doi.org/10.1038/s41467-021-23506-0\">https://doi.org/10.1038/s41467-021-23506-0</a>"},"date_created":"2021-05-28T14:25:50Z","publisher":"Nature Research","article_type":"original","_id":"9431","external_id":{"isi":["000659145000011"]},"has_accepted_license":"1","issue":"1","month":"05","isi":1,"department":[{"_id":"FlSc"}],"date_updated":"2025-04-15T08:24:49Z","article_number":"3226","ddc":["570"],"year":"2021","oa_version":"Published Version","author":[{"full_name":"Obr, Martin","id":"4741CA5A-F248-11E8-B48F-1D18A9856A87","last_name":"Obr","orcid":"0000-0003-1756-6564","first_name":"Martin"},{"full_name":"Ricana, Clifton L.","last_name":"Ricana","first_name":"Clifton L."},{"first_name":"Nadia","full_name":"Nikulin, Nadia","last_name":"Nikulin"},{"first_name":"Jon-Philip R.","last_name":"Feathers","full_name":"Feathers, Jon-Philip R."},{"full_name":"Klanschnig, Marco","last_name":"Klanschnig","first_name":"Marco"},{"id":"3A18A7B8-F248-11E8-B48F-1D18A9856A87","last_name":"Thader","full_name":"Thader, Andreas","first_name":"Andreas"},{"first_name":"Marc C.","full_name":"Johnson, Marc C.","last_name":"Johnson"},{"first_name":"Volker M.","last_name":"Vogt","full_name":"Vogt, Volker M."},{"first_name":"Florian KM","orcid":"0000-0003-4790-8078","last_name":"Schur","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","full_name":"Schur, Florian KM"},{"last_name":"Dick","full_name":"Dick, Robert A.","first_name":"Robert A."}],"acknowledgement":"This work was funded by the National Institute of Allergy and Infectious Diseases under awards R01AI147890 to R.A.D., R01AI150454 to V.M.V, R35GM136258 in support of J-P.R.F, and the Austrian Science Fund (FWF) grant P31445 to F.K.M.S. Access to high-resolution cryo-ET data acquisition at EMBL Heidelberg was supported by iNEXT (grant no. 653706), funded by the Horizon 2020 program of the European Union (PID 4246). We thank Wim Hagen and Felix Weis at EMBL Heidelberg for support in cryo-ET data acquisition. This work made use of the Cornell Center for Materials Research Shared Facilities, which are supported through the NSF MRSEC program (DMR-179875). This research was also supported by the Scientific Service Units (SSUs) of IST Austria through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), and the Electron Microscopy Facility (EMF).","keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"project":[{"_id":"26736D6A-B435-11E9-9278-68D0E5697425","grant_number":"P31445","name":"Structural conservation and diversity in retroviral capsid","call_identifier":"FWF"}],"publication_identifier":{"eissn":["2041-1723"]},"corr_author":"1","fulldoi":"https://doi.org/10.1038/s41467-021-23506-0","acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"abstract":[{"lang":"eng","text":"Inositol hexakisphosphate (IP6) is an assembly cofactor for HIV-1. We report here that IP6 is also used for assembly of Rous sarcoma virus (RSV), a retrovirus from a different genus. IP6 is ~100-fold more potent at promoting RSV mature capsid protein (CA) assembly than observed for HIV-1 and removal of IP6 in cells reduces infectivity by 100-fold. Here, visualized by cryo-electron tomography and subtomogram averaging, mature capsid-like particles show an IP6-like density in the CA hexamer, coordinated by rings of six lysines and six arginines. Phosphate and IP6 have opposing effects on CA in vitro assembly, inducing formation of T = 1 icosahedrons and tubes, respectively, implying that phosphate promotes pentamer and IP6 hexamer formation. Subtomogram averaging and classification optimized for analysis of pleomorphic retrovirus particles reveal that the heterogeneity of mature RSV CA polyhedrons results from an unexpected, intrinsic CA hexamer flexibility. In contrast, the CA pentamer forms rigid units organizing the local architecture. These different features of hexamers and pentamers determine the structural mechanism to form CA polyhedrons of variable shape in mature RSV particles."}],"day":"28","file":[{"success":1,"creator":"kschuh","file_name":"2021_NatureCommunications_Obr.pdf","relation":"main_file","content_type":"application/pdf","file_size":6166295,"checksum":"53ccc53d09a9111143839dbe7784e663","file_id":"9538","access_level":"open_access","date_created":"2021-06-09T15:21:14Z","date_updated":"2021-06-09T15:21:14Z"}],"date_published":"2021-05-28T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","doi":"10.1038/s41467-021-23506-0","scopus_import":"1","type":"journal_article","quality_controlled":"1","publication_status":"published","related_material":{"link":[{"description":"News on IST Homepage","relation":"press_release","url":"https://ist.ac.at/en/news/how-retroviruses-become-infectious/"}]},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"publication":"Nature Communications"},{"publication_status":"published","type":"journal_article","quality_controlled":"1","scopus_import":"1","doi":"10.1038/s41467-021-23854-x","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication":"Nature Communications","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1038/s41467-021-23854-x","publication_identifier":{"eissn":["2041-1723"]},"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"file":[{"creator":"cziletti","success":1,"content_type":"application/pdf","file_size":3397292,"file_name":"2021_NatureComm_Prattes.pdf","relation":"main_file","file_id":"9556","access_level":"open_access","checksum":"40fc24c1310930990b52a8ad1142ee97","date_created":"2021-06-15T18:55:59Z","date_updated":"2021-06-15T18:55:59Z"}],"date_published":"2021-06-09T00:00:00Z","day":"09","acknowledged_ssus":[{"_id":"EM-Fac"}],"abstract":[{"lang":"eng","text":"The hexameric AAA-ATPase Drg1 is a key factor in eukaryotic ribosome biogenesis and initiates cytoplasmic maturation of the large ribosomal subunit by releasing the shuttling maturation factor Rlp24. Drg1 monomers contain two AAA-domains (D1 and D2) that act in a concerted manner. Rlp24 release is inhibited by the drug diazaborine which blocks ATP hydrolysis in D2. The mode of inhibition was unknown. Here we show the first cryo-EM structure of Drg1 revealing the inhibitory mechanism. Diazaborine forms a covalent bond to the 2′-OH of the nucleotide in D2, explaining its specificity for this site. As a consequence, the D2 domain is locked in a rigid, inactive state, stalling the whole Drg1 hexamer. Resistance mechanisms identified include abolished drug binding and altered positioning of the nucleotide. Our results suggest nucleotide-modifying compounds as potential novel inhibitors for AAA-ATPases."}],"department":[{"_id":"EM-Fac"}],"isi":1,"month":"06","issue":"1","has_accepted_license":"1","acknowledgement":"We are deeply grateful to the late Gregor Högenauer who built the foundation for this study with his visionary work on the inhibitor diazaborine and its bacterial target. We thank Rolf Breinbauer for insightful discussions on boron chemistry. We thank Anton Meinhart and Tim Clausen for the valuable discussion of the manuscript. We are indebted to Thomas Köcher for the MS measurement of the diazaborine-ATPγS adduct. We thank the team of the VBCF for support during early phases of this work and the IST Austria Electron Microscopy Facility for providing equipment. The lab of D.H. is supported by Boehringer Ingelheim. The work was funded by FWF projects P32536 and P32977 (to H.B.).","author":[{"full_name":"Prattes, Michael","last_name":"Prattes","first_name":"Michael"},{"first_name":"Irina","last_name":"Grishkovskaya","full_name":"Grishkovskaya, Irina"},{"last_name":"Hodirnau","id":"3661B498-F248-11E8-B48F-1D18A9856A87","full_name":"Hodirnau, Victor-Valentin","orcid":"0000-0003-3904-947X","first_name":"Victor-Valentin"},{"full_name":"Rössler, Ingrid","last_name":"Rössler","first_name":"Ingrid"},{"last_name":"Klein","full_name":"Klein, Isabella","first_name":"Isabella"},{"last_name":"Hetzmannseder","full_name":"Hetzmannseder, Christina","first_name":"Christina"},{"first_name":"Gertrude","full_name":"Zisser, Gertrude","last_name":"Zisser"},{"full_name":"Gruber, Christian C.","last_name":"Gruber","first_name":"Christian C."},{"first_name":"Karl","last_name":"Gruber","full_name":"Gruber, Karl"},{"last_name":"Haselbach","full_name":"Haselbach, David","first_name":"David"},{"first_name":"Helmut","full_name":"Bergler, Helmut","last_name":"Bergler"}],"oa_version":"Published Version","year":"2021","ddc":["570"],"article_number":"3483","date_updated":"2024-10-21T06:02:01Z","status":"public","file_date_updated":"2021-06-15T18:55:59Z","pmid":1,"oa":1,"title":"Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine","intvolume":"        12","external_id":{"isi":["000664874700014"],"pmid":["34108481"]},"_id":"9540","article_type":"original","publisher":"Springer Nature","citation":{"chicago":"Prattes, Michael, Irina Grishkovskaya, Victor-Valentin Hodirnau, Ingrid Rössler, Isabella Klein, Christina Hetzmannseder, Gertrude Zisser, et al. “Structural Basis for Inhibition of the AAA-ATPase Drg1 by Diazaborine.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23854-x\">https://doi.org/10.1038/s41467-021-23854-x</a>.","ieee":"M. Prattes <i>et al.</i>, “Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine,” <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.","apa":"Prattes, M., Grishkovskaya, I., Hodirnau, V.-V., Rössler, I., Klein, I., Hetzmannseder, C., … Bergler, H. (2021). Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-23854-x\">https://doi.org/10.1038/s41467-021-23854-x</a>","short":"M. Prattes, I. Grishkovskaya, V.-V. Hodirnau, I. Rössler, I. Klein, C. Hetzmannseder, G. Zisser, C.C. Gruber, K. Gruber, D. Haselbach, H. Bergler, Nature Communications 12 (2021).","ama":"Prattes M, Grishkovskaya I, Hodirnau V-V, et al. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23854-x\">10.1038/s41467-021-23854-x</a>","ista":"Prattes M, Grishkovskaya I, Hodirnau V-V, Rössler I, Klein I, Hetzmannseder C, Zisser G, Gruber CC, Gruber K, Haselbach D, Bergler H. 2021. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nature Communications. 12(1), 3483.","mla":"Prattes, Michael, et al. “Structural Basis for Inhibition of the AAA-ATPase Drg1 by Diazaborine.” <i>Nature Communications</i>, vol. 12, no. 1, 3483, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23854-x\">10.1038/s41467-021-23854-x</a>."},"article_processing_charge":"No","volume":12,"date_created":"2021-06-10T14:57:45Z"},{"status":"public","pmid":1,"file_date_updated":"2021-12-17T11:34:50Z","intvolume":"        12","title":"Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses","oa":1,"external_id":{"isi":["000655481800014"],"pmid":["34006874"]},"article_type":"original","_id":"9778","publisher":"Springer","citation":{"ieee":"D. H. Vandael, Y. Okamoto, and P. M. Jonas, “Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses,” <i>Nature Communications</i>, vol. 12, no. 1. Springer, 2021.","chicago":"Vandael, David H, Yuji Okamoto, and Peter M Jonas. “Transsynaptic Modulation of Presynaptic Short-Term Plasticity in Hippocampal Mossy Fiber Synapses.” <i>Nature Communications</i>. Springer, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23153-5\">https://doi.org/10.1038/s41467-021-23153-5</a>.","ama":"Vandael DH, Okamoto Y, Jonas PM. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23153-5\">10.1038/s41467-021-23153-5</a>","mla":"Vandael, David H., et al. “Transsynaptic Modulation of Presynaptic Short-Term Plasticity in Hippocampal Mossy Fiber Synapses.” <i>Nature Communications</i>, vol. 12, no. 1, 2912, Springer, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23153-5\">10.1038/s41467-021-23153-5</a>.","ista":"Vandael DH, Okamoto Y, Jonas PM. 2021. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. Nature Communications. 12(1), 2912.","short":"D.H. Vandael, Y. Okamoto, P.M. Jonas, Nature Communications 12 (2021).","apa":"Vandael, D. H., Okamoto, Y., &#38; Jonas, P. M. (2021). Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. <i>Nature Communications</i>. Springer. <a href=\"https://doi.org/10.1038/s41467-021-23153-5\">https://doi.org/10.1038/s41467-021-23153-5</a>"},"date_created":"2021-08-06T07:22:55Z","volume":12,"article_processing_charge":"Yes","department":[{"_id":"PeJo"}],"month":"05","isi":1,"issue":"1","has_accepted_license":"1","OA_type":"gold","author":[{"full_name":"Vandael, David H","last_name":"Vandael","id":"3AE48E0A-F248-11E8-B48F-1D18A9856A87","first_name":"David H","orcid":"0000-0001-7577-1676"},{"full_name":"Okamoto, Yuji","id":"3337E116-F248-11E8-B48F-1D18A9856A87","last_name":"Okamoto","orcid":"0000-0003-0408-6094","first_name":"Yuji"},{"first_name":"Peter M","orcid":"0000-0001-5001-4804","last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","full_name":"Jonas, Peter M"}],"acknowledgement":"We thank Drs. Carolina Borges-Merjane and Jose Guzman for critically reading the manuscript, and Pablo Castillo for discussions. We are grateful to Alois Schlögl for help with analysis, Florian Marr for excellent technical assistance and cell reconstruction, Christina Altmutter for technical help, Eleftheria Kralli-Beller for manuscript editing, and the Scientific Service Units of IST Austria for support. This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No 692692) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award), both to P.J.","year":"2021","oa_version":"Published Version","ddc":["570"],"date_updated":"2025-06-12T06:28:45Z","article_number":"2912","fulldoi":"https://doi.org/10.1038/s41467-021-23153-5","corr_author":"1","ec_funded":1,"publication_identifier":{"issn":["2041-1723"]},"keyword":["general physics and astronomy","general biochemistry","genetics and molecular biology","general chemistry"],"project":[{"call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse","grant_number":"692692","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FWF","name":"Synaptic communication in neuronal microcircuits","grant_number":"Z00312","_id":"25C5A090-B435-11E9-9278-68D0E5697425"}],"date_published":"2021-05-18T00:00:00Z","file":[{"file_id":"10563","access_level":"open_access","checksum":"6036a8cdae95e1707c2a04d54e325ff4","date_created":"2021-12-17T11:34:50Z","date_updated":"2021-12-17T11:34:50Z","creator":"kschuh","success":1,"content_type":"application/pdf","file_size":3108845,"relation":"main_file","file_name":"2021_NatureCommunications_Vandael.pdf"}],"day":"18","OA_place":"publisher","acknowledged_ssus":[{"_id":"SSU"}],"abstract":[{"text":"The hippocampal mossy fiber synapse is a key synapse of the trisynaptic circuit. Post-tetanic potentiation (PTP) is the most powerful form of plasticity at this synaptic connection. It is widely believed that mossy fiber PTP is an entirely presynaptic phenomenon, implying that PTP induction is input-specific, and requires neither activity of multiple inputs nor stimulation of postsynaptic neurons. To directly test cooperativity and associativity, we made paired recordings between single mossy fiber terminals and postsynaptic CA3 pyramidal neurons in rat brain slices. By stimulating non-overlapping mossy fiber inputs converging onto single CA3 neurons, we confirm that PTP is input-specific and non-cooperative. Unexpectedly, mossy fiber PTP exhibits anti-associative induction properties. EPSCs show only minimal PTP after combined pre- and postsynaptic high-frequency stimulation with intact postsynaptic Ca2+ signaling, but marked PTP in the absence of postsynaptic spiking and after suppression of postsynaptic Ca2+ signaling (10 mM EGTA). PTP is largely recovered by inhibitors of voltage-gated R- and L-type Ca2+ channels, group II mGluRs, and vacuolar-type H+-ATPase, suggesting the involvement of retrograde vesicular glutamate signaling. Transsynaptic regulation of PTP extends the repertoire of synaptic computations, implementing a brake on mossy fiber detonation and a “smart teacher” function of hippocampal mossy fiber synapses.","lang":"eng"}],"type":"journal_article","quality_controlled":"1","publication_status":"published","doi":"10.1038/s41467-021-23153-5","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Nature Communications","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"related_material":{"link":[{"url":"https://ist.ac.at/en/news/synaptic-transmission-not-a-one-way-street/","relation":"press_release","description":"News on IST Homepage"}]}},{"publication_identifier":{"eissn":["1755-4349"],"issn":["1755-4330"]},"keyword":["General Chemistry","General Chemical Engineering"],"fulldoi":"https://doi.org/10.1038/s41557-021-00643-z","corr_author":"1","day":"15","abstract":[{"text":"Aprotic alkali metal–O2 batteries face two major obstacles to their chemistry occurring efficiently, the insulating nature of the formed alkali superoxides/peroxides and parasitic reactions that are caused by the highly reactive singlet oxygen (1O2). Redox mediators are recognized to be key for improving rechargeability. However, it is unclear how they affect 1O2 formation, which hinders strategies for their improvement. Here we clarify the mechanism of mediated peroxide and superoxide oxidation and thus explain how redox mediators either enhance or suppress 1O2 formation. We show that charging commences with peroxide oxidation to a superoxide intermediate and that redox potentials above ~3.5 V versus Li/Li+ drive 1O2 evolution from superoxide oxidation, while disproportionation always generates some 1O2. We find that 1O2 suppression requires oxidation to be faster than the generation of 1O2 from disproportionation. Oxidation rates decrease with growing driving force following Marcus inverted-region behaviour, establishing a region of maximum rate.","lang":"eng"}],"acknowledged_ssus":[{"_id":"M-Shop"}],"file":[{"access_level":"open_access","file_id":"9276","checksum":"3ee3f8dd79ed1b7bb0929fce184c8012","date_updated":"2021-09-16T22:30:03Z","date_created":"2021-03-22T11:46:00Z","creator":"dernst","file_size":1811448,"embargo":"2021-09-15","content_type":"application/pdf","relation":"main_file","file_name":"2021_NatureChem_Petit_acceptedVersion.pdf"}],"date_published":"2021-03-15T00:00:00Z","page":"465-471","scopus_import":"1","doi":"10.1038/s41557-021-00643-z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication_status":"published","quality_controlled":"1","type":"journal_article","language":[{"iso":"eng"}],"publication":"Nature Chemistry","oa":1,"intvolume":"        13","title":"Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation","status":"public","pmid":1,"file_date_updated":"2021-09-16T22:30:03Z","publisher":"Springer Nature","date_created":"2021-03-16T11:12:20Z","article_processing_charge":"No","citation":{"short":"Y.K. Petit, E. Mourad, C. Prehal, C. Leypold, A. Windischbacher, D. Mijailovic, C. Slugovc, S.M. Borisov, E. Zojer, S. Brutti, O. Fontaine, S.A. Freunberger, Nature Chemistry 13 (2021) 465–471.","apa":"Petit, Y. K., Mourad, E., Prehal, C., Leypold, C., Windischbacher, A., Mijailovic, D., … Freunberger, S. A. (2021). Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. <i>Nature Chemistry</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41557-021-00643-z\">https://doi.org/10.1038/s41557-021-00643-z</a>","ista":"Petit YK, Mourad E, Prehal C, Leypold C, Windischbacher A, Mijailovic D, Slugovc C, Borisov SM, Zojer E, Brutti S, Fontaine O, Freunberger SA. 2021. Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. Nature Chemistry. 13(5), 465–471.","mla":"Petit, Yann K., et al. “Mechanism of Mediated Alkali Peroxide Oxidation and Triplet versus Singlet Oxygen Formation.” <i>Nature Chemistry</i>, vol. 13, no. 5, Springer Nature, 2021, pp. 465–71, doi:<a href=\"https://doi.org/10.1038/s41557-021-00643-z\">10.1038/s41557-021-00643-z</a>.","ama":"Petit YK, Mourad E, Prehal C, et al. Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. <i>Nature Chemistry</i>. 2021;13(5):465-471. doi:<a href=\"https://doi.org/10.1038/s41557-021-00643-z\">10.1038/s41557-021-00643-z</a>","chicago":"Petit, Yann K., Eléonore Mourad, Christian Prehal, Christian Leypold, Andreas Windischbacher, Daniel Mijailovic, Christian Slugovc, et al. “Mechanism of Mediated Alkali Peroxide Oxidation and Triplet versus Singlet Oxygen Formation.” <i>Nature Chemistry</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41557-021-00643-z\">https://doi.org/10.1038/s41557-021-00643-z</a>.","ieee":"Y. K. Petit <i>et al.</i>, “Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation,” <i>Nature Chemistry</i>, vol. 13, no. 5. Springer Nature, pp. 465–471, 2021."},"volume":13,"external_id":{"pmid":["33723377"],"isi":["000629296400001"]},"_id":"9250","article_type":"original","issue":"5","has_accepted_license":"1","department":[{"_id":"StFr"}],"isi":1,"month":"03","ddc":["540"],"date_updated":"2024-10-09T21:00:28Z","author":[{"last_name":"Petit","full_name":"Petit, Yann K.","first_name":"Yann K."},{"first_name":"Eléonore","full_name":"Mourad, Eléonore","last_name":"Mourad"},{"first_name":"Christian","full_name":"Prehal, Christian","last_name":"Prehal"},{"first_name":"Christian","last_name":"Leypold","full_name":"Leypold, Christian"},{"first_name":"Andreas","full_name":"Windischbacher, Andreas","last_name":"Windischbacher"},{"full_name":"Mijailovic, Daniel","last_name":"Mijailovic","first_name":"Daniel"},{"first_name":"Christian","full_name":"Slugovc, Christian","last_name":"Slugovc"},{"first_name":"Sergey M.","full_name":"Borisov, Sergey M.","last_name":"Borisov"},{"first_name":"Egbert","last_name":"Zojer","full_name":"Zojer, Egbert"},{"first_name":"Sergio","full_name":"Brutti, Sergio","last_name":"Brutti"},{"last_name":"Fontaine","full_name":"Fontaine, Olivier","first_name":"Olivier"},{"orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"}],"acknowledgement":"S.A.F. is indebted to the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 636069) as well as IST Austria. O.F thanks the French National Research Agency (STORE-EX Labex Project ANR-10-LABX-76-01). We thank EL-Cell GmbH (Hamburg, Germany) for the pressure test cell. We thank R. Saf for help with the mass spectrometry, J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH, G. Strohmeier and R. Fürst for HPLC measurements and S. Mondal and S. Stadlbauer for kinetic measurements.","year":"2021","oa_version":"Submitted Version"}]