[{"publisher":"Springer Nature","main_file_link":[{"url":"https://doi.org/10.1038/s41467-023-38540-3","open_access":"1"}],"volume":14,"citation":{"short":"J. Hales, U. Bajpai, T. Liu, D.R. Baykusheva, M. Li, M. Mitrano, Y. Wang, Nature Communications 14 (2023).","chicago":"Hales, Jordyn, Utkarsh Bajpai, Tongtong Liu, Denitsa Rangelova Baykusheva, Mingda Li, Matteo Mitrano, and Yao Wang. “Witnessing Light-Driven Entanglement Using Time-Resolved Resonant Inelastic X-Ray Scattering.” <i>Nature Communications</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1038/s41467-023-38540-3\">https://doi.org/10.1038/s41467-023-38540-3</a>.","ista":"Hales J, Bajpai U, Liu T, Baykusheva DR, Li M, Mitrano M, Wang Y. 2023. Witnessing light-driven entanglement using time-resolved resonant inelastic X-ray scattering. Nature Communications. 14, 3512.","mla":"Hales, Jordyn, et al. “Witnessing Light-Driven Entanglement Using Time-Resolved Resonant Inelastic X-Ray Scattering.” <i>Nature Communications</i>, vol. 14, 3512, Springer Nature, 2023, doi:<a href=\"https://doi.org/10.1038/s41467-023-38540-3\">10.1038/s41467-023-38540-3</a>.","ama":"Hales J, Bajpai U, Liu T, et al. Witnessing light-driven entanglement using time-resolved resonant inelastic X-ray scattering. <i>Nature Communications</i>. 2023;14. doi:<a href=\"https://doi.org/10.1038/s41467-023-38540-3\">10.1038/s41467-023-38540-3</a>","ieee":"J. Hales <i>et al.</i>, “Witnessing light-driven entanglement using time-resolved resonant inelastic X-ray scattering,” <i>Nature Communications</i>, vol. 14. Springer Nature, 2023.","apa":"Hales, J., Bajpai, U., Liu, T., Baykusheva, D. R., Li, M., Mitrano, M., &#38; Wang, Y. (2023). Witnessing light-driven entanglement using time-resolved resonant inelastic X-ray scattering. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-023-38540-3\">https://doi.org/10.1038/s41467-023-38540-3</a>"},"pmid":1,"type":"journal_article","abstract":[{"lang":"eng","text":"Characterizing and controlling entanglement in quantum materials is crucial for the development of next-generation quantum technologies. However, defining a quantifiable figure of merit for entanglement in macroscopic solids is theoretically and experimentally challenging. At equilibrium the presence of entanglement can be diagnosed by extracting entanglement witnesses from spectroscopic observables and a nonequilibrium extension of this method could lead to the discovery of novel dynamical phenomena. Here, we propose a systematic approach to quantify the time-dependent quantum Fisher information and entanglement depth of transient states of quantum materials with time-resolved resonant inelastic x-ray scattering. Using a quarter-filled extended Hubbard model as an example, we benchmark the efficiency of this approach and predict a light-enhanced many-body entanglement due to the proximity to a phase boundary. Our work sets the stage for experimentally witnessing and controlling entanglement in light-driven quantum materials via ultrafast spectroscopic measurements."}],"extern":"1","quality_controlled":"1","month":"06","scopus_import":"1","_id":"13989","external_id":{"pmid":["37316515"],"arxiv":["2209.02283"]},"publication_status":"published","date_created":"2023-08-09T13:06:59Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"publication":"Nature Communications","article_number":"3512","article_type":"original","year":"2023","publication_identifier":{"eissn":["2041-1723"]},"oa":1,"doi":"10.1038/s41467-023-38540-3","day":"14","date_published":"2023-06-14T00:00:00Z","intvolume":"        14","status":"public","language":[{"iso":"eng"}],"article_processing_charge":"No","author":[{"first_name":"Jordyn","last_name":"Hales","full_name":"Hales, Jordyn"},{"first_name":"Utkarsh","full_name":"Bajpai, Utkarsh","last_name":"Bajpai"},{"first_name":"Tongtong","full_name":"Liu, Tongtong","last_name":"Liu"},{"first_name":"Denitsa Rangelova","full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","id":"71b4d059-2a03-11ee-914d-dfa3beed6530"},{"full_name":"Li, Mingda","last_name":"Li","first_name":"Mingda"},{"first_name":"Matteo","last_name":"Mitrano","full_name":"Mitrano, Matteo"},{"first_name":"Yao","last_name":"Wang","full_name":"Wang, Yao"}],"title":"Witnessing light-driven entanglement using time-resolved resonant inelastic X-ray scattering","date_updated":"2023-08-22T06:50:04Z","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"oa_version":"Published Version"},{"publisher":"Springer Nature","department":[{"_id":"Bio"}],"volume":13,"quality_controlled":"1","abstract":[{"lang":"eng","text":"Current methods for assessing cell proliferation in 3D scaffolds rely on changes in metabolic activity or total DNA, however, direct quantification of cell number in 3D scaffolds remains a challenge. To address this issue, we developed an unbiased stereology approach that uses systematic-random sampling and thin focal-plane optical sectioning of the scaffolds followed by estimation of total cell number (StereoCount). This approach was validated against an indirect method for measuring the total DNA (DNA content); and the Bürker counting chamber, the current reference method for quantifying cell number. We assessed the total cell number for cell seeding density (cells per unit volume) across four values and compared the methods in terms of accuracy, ease-of-use and time demands. The accuracy of StereoCount markedly outperformed the DNA content for cases with ~ 10,000 and ~ 125,000 cells/scaffold. For cases with ~ 250,000 and ~ 375,000 cells/scaffold both StereoCount and DNA content showed lower accuracy than the Bürker but did not differ from each other. In terms of ease-of-use, there was a strong advantage for the StereoCount due to output in terms of absolute cell numbers along with the possibility for an overview of cell distribution and future use of automation for high throughput analysis. Taking together, the StereoCount method is an efficient approach for direct cell quantification in 3D collagen scaffolds. Its major benefit is that automated StereoCount could accelerate research using 3D scaffolds focused on drug discovery for a wide variety of human diseases."}],"type":"journal_article","pmid":1,"citation":{"ama":"Zavadakova A, Vistejnova L, Belinova T, Tichanek F, Bilikova D, Mouton PR. Novel stereological method for estimation of cell counts in 3D collagen scaffolds. <i>Scientific Reports</i>. 2023;13(1). doi:<a href=\"https://doi.org/10.1038/s41598-023-35162-z\">10.1038/s41598-023-35162-z</a>","ieee":"A. Zavadakova, L. Vistejnova, T. Belinova, F. Tichanek, D. Bilikova, and P. R. Mouton, “Novel stereological method for estimation of cell counts in 3D collagen scaffolds,” <i>Scientific Reports</i>, vol. 13, no. 1. Springer Nature, 2023.","apa":"Zavadakova, A., Vistejnova, L., Belinova, T., Tichanek, F., Bilikova, D., &#38; Mouton, P. R. (2023). Novel stereological method for estimation of cell counts in 3D collagen scaffolds. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-023-35162-z\">https://doi.org/10.1038/s41598-023-35162-z</a>","mla":"Zavadakova, Anna, et al. “Novel Stereological Method for Estimation of Cell Counts in 3D Collagen Scaffolds.” <i>Scientific Reports</i>, vol. 13, no. 1, 7959, Springer Nature, 2023, doi:<a href=\"https://doi.org/10.1038/s41598-023-35162-z\">10.1038/s41598-023-35162-z</a>.","chicago":"Zavadakova, Anna, Lucie Vistejnova, Tereza Belinova, Filip Tichanek, Dagmar Bilikova, and Peter R. Mouton. “Novel Stereological Method for Estimation of Cell Counts in 3D Collagen Scaffolds.” <i>Scientific Reports</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1038/s41598-023-35162-z\">https://doi.org/10.1038/s41598-023-35162-z</a>.","ista":"Zavadakova A, Vistejnova L, Belinova T, Tichanek F, Bilikova D, Mouton PR. 2023. Novel stereological method for estimation of cell counts in 3D collagen scaffolds. Scientific Reports. 13(1), 7959.","short":"A. Zavadakova, L. Vistejnova, T. Belinova, F. Tichanek, D. Bilikova, P.R. Mouton, Scientific Reports 13 (2023)."},"scopus_import":"1","issue":"1","month":"05","_id":"13033","external_id":{"pmid":["37198326"],"isi":["000995271600104"]},"date_created":"2023-05-19T11:12:25Z","publication_status":"published","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Scientific Reports","isi":1,"year":"2023","acknowledgement":"The study was supported by Project No. CZ.02.1.01/0.0/0.0/16_019/0000787 “Fighting INfectious Diseases”, awarded by the MEYS CR, financed from EFRR, by the Cooperatio Program, research area DIAG and research area MED/DIAG, by the profiBONE project (TO01000309) benefitting from a € (1.433.000) grant from Iceland, Liechtenstein and Norway through the EEA Grants and the Technology Agency of the Czech Republic and by a Grant (#1926990) to PRM and SRC Biosciences from the National Science Foundation (U.S. Public Health Service). The authors acknowledge the invaluable assistance provided by Iveta Paurova via her support in terms of the provision of laboratory services.","article_type":"original","publication_identifier":{"issn":["2045-2322"]},"article_number":"7959","intvolume":"        13","date_published":"2023-05-17T00:00:00Z","doi":"10.1038/s41598-023-35162-z","day":"17","file":[{"access_level":"open_access","creator":"dernst","file_size":3055077,"success":1,"date_created":"2023-05-22T07:57:37Z","file_name":"2023_ScientificReports_Zavadakova.pdf","checksum":"8c1b769693ff4288df8376e59ad1176d","content_type":"application/pdf","relation":"main_file","date_updated":"2023-05-22T07:57:37Z","file_id":"13047"}],"oa":1,"file_date_updated":"2023-05-22T07:57:37Z","has_accepted_license":"1","article_processing_charge":"No","status":"public","language":[{"iso":"eng"}],"related_material":{"link":[{"url":"https://doi.org/10.1038/s41598-023-37265-z","relation":"erratum"}]},"date_updated":"2025-04-23T08:56:48Z","author":[{"last_name":"Zavadakova","full_name":"Zavadakova, Anna","first_name":"Anna"},{"first_name":"Lucie","full_name":"Vistejnova, Lucie","last_name":"Vistejnova"},{"first_name":"Tereza","last_name":"Belinova","full_name":"Belinova, Tereza","id":"0bf89b6a-d28b-11eb-8bd6-f43768e4d368"},{"first_name":"Filip","full_name":"Tichanek, Filip","last_name":"Tichanek"},{"full_name":"Bilikova, Dagmar","last_name":"Bilikova","first_name":"Dagmar"},{"last_name":"Mouton","full_name":"Mouton, Peter R.","first_name":"Peter R."}],"title":"Novel stereological method for estimation of cell counts in 3D collagen scaffolds","keyword":["Multidisciplinary"],"oa_version":"Published Version"},{"article_type":"original","year":"2023","publication_identifier":{"issn":["2375-2548"]},"acknowledgement":"This work was supported by a postdoctoral fellowship from the Swedish Society for Medical Research to J.R., a CAPES-STINT joint grant to R.G.G. and L.S.W., a PhD fellowship from Karolinska Institutet (KID) to E.D., a PhD fellowship from Fundação para a Ciência e a Tecnologia and European Social Fund to M.M.S.O., the program of fundamental research (theme 65.1) of the Institute for Biomedical Problems of the Russian Academy of Sciences (IBMP RAS) to A.A.S., S.M.S., V.A.S., O.V.K., D.D.V., K.D.O., M.P.R., and S.A.P., the Tamkeen under the NYU Abu Dhabi Research Institute Award to the NYUAD Center for Genomics and Systems Biology (ADHPG-CGSB) to P.P., the Knut and Alice Wallenberg foundation to C.K., the Swedish National Space Agency to N.V.K. and L.S.W., Swedish Research Council, Gösta Fraenckel Foundation, and Karolinska Institutet to L.S.W.","article_number":"adg1610","date_published":"2023-08-25T00:00:00Z","intvolume":"         9","oa":1,"file":[{"access_level":"open_access","creator":"dernst","file_size":1596639,"date_created":"2024-01-16T09:35:28Z","file_name":"2023_ScienceAdvances_GallardoDodd.pdf","success":1,"content_type":"application/pdf","checksum":"b9072e20e2d5d9d34d2c53319bafee41","relation":"main_file","date_updated":"2024-01-16T09:35:28Z","file_id":"14809"}],"day":"25","doi":"10.1126/sciadv.adg1610","ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"publication":"Science Advances","keyword":["Multidisciplinary"],"oa_version":"Published Version","has_accepted_license":"1","article_processing_charge":"Yes","file_date_updated":"2024-01-16T09:35:28Z","language":[{"iso":"eng"}],"status":"public","date_updated":"2024-09-09T08:03:13Z","title":"Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells","author":[{"last_name":"Gallardo-Dodd","full_name":"Gallardo-Dodd, Carlos J.","first_name":"Carlos J."},{"first_name":"Christian","last_name":"Oertlin","full_name":"Oertlin, Christian"},{"full_name":"Record, Julien","last_name":"Record","first_name":"Julien"},{"last_name":"Galvani","full_name":"Galvani, Rômulo G.","first_name":"Rômulo G."},{"first_name":"Christian","last_name":"Sommerauer","full_name":"Sommerauer, Christian"},{"first_name":"Nikolai V.","last_name":"Kuznetsov","full_name":"Kuznetsov, Nikolai V."},{"first_name":"Evangelos","full_name":"Doukoumopoulos, Evangelos","last_name":"Doukoumopoulos"},{"first_name":"Liaqat","last_name":"Ali","full_name":"Ali, Liaqat"},{"first_name":"Mariana M. S.","full_name":"Oliveira, Mariana M. S.","last_name":"Oliveira"},{"last_name":"Seitz","full_name":"Seitz, Christina","first_name":"Christina"},{"first_name":"Mathias","id":"4986e21c-eb97-11eb-a6c2-a4ef0b629971","last_name":"Percipalle","full_name":"Percipalle, Mathias"},{"last_name":"Nikić","full_name":"Nikić, Tijana","first_name":"Tijana"},{"full_name":"Sadova, Anastasia A.","last_name":"Sadova","first_name":"Anastasia A."},{"full_name":"Shulgina, Sofia M.","last_name":"Shulgina","first_name":"Sofia M."},{"first_name":"Vjacheslav A.","last_name":"Shmarov","full_name":"Shmarov, Vjacheslav A."},{"last_name":"Kutko","full_name":"Kutko, Olga V.","first_name":"Olga V."},{"last_name":"Vlasova","full_name":"Vlasova, Daria D.","first_name":"Daria D."},{"last_name":"Orlova","full_name":"Orlova, Kseniya D.","first_name":"Kseniya D."},{"last_name":"Rykova","full_name":"Rykova, Marina P.","first_name":"Marina P."},{"full_name":"Andersson, John","last_name":"Andersson","first_name":"John"},{"first_name":"Piergiorgio","last_name":"Percipalle","full_name":"Percipalle, Piergiorgio"},{"full_name":"Kutter, Claudia","last_name":"Kutter","first_name":"Claudia"},{"first_name":"Sergey A.","last_name":"Ponomarev","full_name":"Ponomarev, Sergey A."},{"first_name":"Lisa S.","full_name":"Westerberg, Lisa S.","last_name":"Westerberg"}],"quality_controlled":"1","citation":{"short":"C.J. Gallardo-Dodd, C. Oertlin, J. Record, R.G. Galvani, C. Sommerauer, N.V. Kuznetsov, E. Doukoumopoulos, L. Ali, M.M.S. Oliveira, C. Seitz, M. Percipalle, T. Nikić, A.A. Sadova, S.M. Shulgina, V.A. Shmarov, O.V. Kutko, D.D. Vlasova, K.D. Orlova, M.P. Rykova, J. Andersson, P. Percipalle, C. Kutter, S.A. Ponomarev, L.S. Westerberg, Science Advances 9 (2023).","ista":"Gallardo-Dodd CJ, Oertlin C, Record J, Galvani RG, Sommerauer C, Kuznetsov NV, Doukoumopoulos E, Ali L, Oliveira MMS, Seitz C, Percipalle M, Nikić T, Sadova AA, Shulgina SM, Shmarov VA, Kutko OV, Vlasova DD, Orlova KD, Rykova MP, Andersson J, Percipalle P, Kutter C, Ponomarev SA, Westerberg LS. 2023. Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells. Science Advances. 9(34), adg1610.","chicago":"Gallardo-Dodd, Carlos J., Christian Oertlin, Julien Record, Rômulo G. Galvani, Christian Sommerauer, Nikolai V. Kuznetsov, Evangelos Doukoumopoulos, et al. “Exposure of Volunteers to Microgravity by Dry Immersion Bed over 21 Days Results in Gene Expression Changes and Adaptation of T Cells.” <i>Science Advances</i>. American Association for the Advancement of Science, 2023. <a href=\"https://doi.org/10.1126/sciadv.adg1610\">https://doi.org/10.1126/sciadv.adg1610</a>.","mla":"Gallardo-Dodd, Carlos J., et al. “Exposure of Volunteers to Microgravity by Dry Immersion Bed over 21 Days Results in Gene Expression Changes and Adaptation of T Cells.” <i>Science Advances</i>, vol. 9, no. 34, adg1610, American Association for the Advancement of Science, 2023, doi:<a href=\"https://doi.org/10.1126/sciadv.adg1610\">10.1126/sciadv.adg1610</a>.","ieee":"C. J. Gallardo-Dodd <i>et al.</i>, “Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells,” <i>Science Advances</i>, vol. 9, no. 34. American Association for the Advancement of Science, 2023.","apa":"Gallardo-Dodd, C. J., Oertlin, C., Record, J., Galvani, R. G., Sommerauer, C., Kuznetsov, N. V., … Westerberg, L. S. (2023). Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.adg1610\">https://doi.org/10.1126/sciadv.adg1610</a>","ama":"Gallardo-Dodd CJ, Oertlin C, Record J, et al. Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells. <i>Science Advances</i>. 2023;9(34). doi:<a href=\"https://doi.org/10.1126/sciadv.adg1610\">10.1126/sciadv.adg1610</a>"},"pmid":1,"type":"journal_article","abstract":[{"text":"The next steps of deep space exploration are manned missions to Moon and Mars. For safe space missions for crew members, it is important to understand the impact of space flight on the immune system. We studied the effects of 21 days dry immersion (DI) exposure on the transcriptomes of T cells isolated from blood samples of eight healthy volunteers. Samples were collected 7 days before DI, at day 7, 14, and 21 during DI, and 7 days after DI. RNA sequencing of CD3+T cells revealed transcriptional alterations across all time points, with most changes occurring 14 days after DI exposure. At day 21, T cells showed evidence of adaptation with a transcriptional profile resembling that of 7 days before DI. At 7 days after DI, T cells again changed their transcriptional profile. These data suggest that T cells adapt by rewiring their transcriptomes in response to simulated weightlessness and that remodeling cues persist when reexposed to normal gravity.","lang":"eng"}],"publisher":"American Association for the Advancement of Science","department":[{"_id":"FlSc"}],"volume":9,"external_id":{"pmid":["37624890"],"isi":["001054596800007"]},"date_created":"2024-01-10T09:48:01Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","issue":"34","month":"08","_id":"14784"},{"isi":1,"publication":"Science Advances","ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"grant_number":"P33367","name":"Structure and isoform diversity of the Arp2/3 complex","_id":"9B954C5C-BA93-11EA-9121-9846C619BF3A"}],"date_published":"2023-01-20T00:00:00Z","intvolume":"         9","file":[{"relation":"main_file","content_type":"application/pdf","checksum":"ce81a6d0b84170e5e8c62f6acfa15d9e","file_id":"12335","date_updated":"2023-01-23T07:45:54Z","access_level":"open_access","date_created":"2023-01-23T07:45:54Z","success":1,"file_name":"2023_ScienceAdvances_Faessler.pdf","file_size":1756234,"creator":"dernst"}],"oa":1,"doi":"10.1126/sciadv.add6495","day":"20","article_type":"original","publication_identifier":{"issn":["2375-2548"]},"year":"2023","acknowledgement":"We would like to thank K. von Peinen and B. Denker (Helmholtz Centre for Infection Research, Braunschweig, Germany) for experimental and technical assistance, respectively.\r\nThis research was supported by the Scientific Service Units (SSUs) of ISTA through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), the Imaging and Optics facility (IOF), and the Electron Microscopy Facility (EMF). We acknowledge support from ISTA and from the Austrian Science Fund (FWF) (P33367) to F.K.M.S., from the Research Training Group GRK2223 and the Helmholtz Society to K.R,. and from the Deutsche Forschungsgemeinschaft (DFG) to J.F. and K.R.","article_number":"add6495","acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"Bio"},{"_id":"EM-Fac"}],"date_updated":"2026-04-07T12:59:44Z","related_material":{"record":[{"relation":"research_data","id":"14562","status":"public"},{"status":"public","relation":"dissertation_contains","id":"18766"}]},"author":[{"last_name":"Fäßler","full_name":"Fäßler, Florian","id":"404F5528-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7149-769X","first_name":"Florian"},{"first_name":"Manjunath","orcid":"0000-0003-2311-2112","full_name":"Javoor, Manjunath","last_name":"Javoor","id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2"},{"orcid":"0000-0002-3616-8580","full_name":"Datler, Julia","last_name":"Datler","id":"3B12E2E6-F248-11E8-B48F-1D18A9856A87","first_name":"Julia"},{"first_name":"Hermann","last_name":"Döring","full_name":"Döring, Hermann"},{"last_name":"Hofer","full_name":"Hofer, Florian","id":"b9d234ba-9e33-11ed-95b6-cd561df280e6","first_name":"Florian"},{"last_name":"Dimchev","full_name":"Dimchev, Georgi A","id":"38C393BE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8370-6161","first_name":"Georgi A"},{"orcid":"0000-0003-3904-947X","last_name":"Hodirnau","full_name":"Hodirnau, Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87","first_name":"Victor-Valentin"},{"first_name":"Jan","full_name":"Faix, Jan","last_name":"Faix"},{"first_name":"Klemens","last_name":"Rottner","full_name":"Rottner, Klemens"},{"orcid":"0000-0003-4790-8078","last_name":"Schur","full_name":"Schur, Florian KM","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian KM"}],"title":"ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning","has_accepted_license":"1","article_processing_charge":"No","file_date_updated":"2023-01-23T07:45:54Z","status":"public","language":[{"iso":"eng"}],"oa_version":"Published Version","keyword":["Multidisciplinary"],"department":[{"_id":"FlSc"},{"_id":"EM-Fac"}],"volume":9,"publisher":"American Association for the Advancement of Science","corr_author":"1","quality_controlled":"1","citation":{"short":"F. Fäßler, M. Javoor, J. Datler, H. Döring, F. Hofer, G.A. Dimchev, V.-V. Hodirnau, J. Faix, K. Rottner, F.K. Schur, Science Advances 9 (2023).","chicago":"Fäßler, Florian, Manjunath Javoor, Julia Datler, Hermann Döring, Florian Hofer, Georgi A Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner, and Florian KM Schur. “ArpC5 Isoforms Regulate Arp2/3 Complex–Dependent Protrusion through Differential Ena/VASP Positioning.” <i>Science Advances</i>. American Association for the Advancement of Science, 2023. <a href=\"https://doi.org/10.1126/sciadv.add6495\">https://doi.org/10.1126/sciadv.add6495</a>.","ista":"Fäßler F, Javoor M, Datler J, Döring H, Hofer F, Dimchev GA, Hodirnau V-V, Faix J, Rottner K, Schur FK. 2023. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. Science Advances. 9(3), add6495.","mla":"Fäßler, Florian, et al. “ArpC5 Isoforms Regulate Arp2/3 Complex–Dependent Protrusion through Differential Ena/VASP Positioning.” <i>Science Advances</i>, vol. 9, no. 3, add6495, American Association for the Advancement of Science, 2023, doi:<a href=\"https://doi.org/10.1126/sciadv.add6495\">10.1126/sciadv.add6495</a>.","ama":"Fäßler F, Javoor M, Datler J, et al. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. <i>Science Advances</i>. 2023;9(3). doi:<a href=\"https://doi.org/10.1126/sciadv.add6495\">10.1126/sciadv.add6495</a>","apa":"Fäßler, F., Javoor, M., Datler, J., Döring, H., Hofer, F., Dimchev, G. A., … Schur, F. K. (2023). ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.add6495\">https://doi.org/10.1126/sciadv.add6495</a>","ieee":"F. Fäßler <i>et al.</i>, “ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning,” <i>Science Advances</i>, vol. 9, no. 3. American Association for the Advancement of Science, 2023."},"type":"journal_article","pmid":1,"abstract":[{"lang":"eng","text":"Regulation of the Arp2/3 complex is required for productive nucleation of branched actin networks. An emerging aspect of regulation is the incorporation of subunit isoforms into the Arp2/3 complex. Specifically, both ArpC5 subunit isoforms, ArpC5 and ArpC5L, have been reported to fine-tune nucleation activity and branch junction stability. We have combined reverse genetics and cellular structural biology to describe how ArpC5 and ArpC5L differentially affect cell migration. Both define the structural stability of ArpC1 in branch junctions and, in turn, by determining protrusion characteristics, affect protein dynamics and actin network ultrastructure. ArpC5 isoforms also affect the positioning of members of the Ena/Vasodilator-stimulated phosphoprotein (VASP) family of actin filament elongators, which mediate ArpC5 isoform–specific effects on the actin assembly level. Our results suggest that ArpC5 and Ena/VASP proteins are part of a signaling pathway enhancing cell migration.</jats:p>"}],"_id":"12334","issue":"3","scopus_import":"1","month":"01","date_created":"2023-01-23T07:26:42Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","external_id":{"pmid":["36662867"],"isi":["000964550100015"]}},{"_id":"13106","month":"05","issue":"6646","scopus_import":"1","publication_status":"published","date_created":"2023-05-31T11:39:24Z","external_id":{"pmid":["37200415"],"arxiv":["2301.03315"],"isi":["000996515200004"]},"volume":380,"department":[{"_id":"JoFi"}],"corr_author":"1","publisher":"American Association for the Advancement of Science","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2301.03315","open_access":"1"}],"citation":{"short":"R. Sahu, L. Qiu, W.J. Hease, G.M. Arnold, Y. Minoguchi, P. Rabl, J.M. Fink, Science 380 (2023) 718–721.","apa":"Sahu, R., Qiu, L., Hease, W. J., Arnold, G. M., Minoguchi, Y., Rabl, P., &#38; Fink, J. M. (2023). Entangling microwaves with light. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.adg3812\">https://doi.org/10.1126/science.adg3812</a>","ama":"Sahu R, Qiu L, Hease WJ, et al. Entangling microwaves with light. <i>Science</i>. 2023;380(6646):718-721. doi:<a href=\"https://doi.org/10.1126/science.adg3812\">10.1126/science.adg3812</a>","ieee":"R. Sahu <i>et al.</i>, “Entangling microwaves with light,” <i>Science</i>, vol. 380, no. 6646. American Association for the Advancement of Science, pp. 718–721, 2023.","mla":"Sahu, Rishabh, et al. “Entangling Microwaves with Light.” <i>Science</i>, vol. 380, no. 6646, American Association for the Advancement of Science, 2023, pp. 718–21, doi:<a href=\"https://doi.org/10.1126/science.adg3812\">10.1126/science.adg3812</a>.","ista":"Sahu R, Qiu L, Hease WJ, Arnold GM, Minoguchi Y, Rabl P, Fink JM. 2023. Entangling microwaves with light. Science. 380(6646), 718–721.","chicago":"Sahu, Rishabh, Liu Qiu, William J Hease, Georg M Arnold, Y. Minoguchi, P. Rabl, and Johannes M Fink. “Entangling Microwaves with Light.” <i>Science</i>. American Association for the Advancement of Science, 2023. <a href=\"https://doi.org/10.1126/science.adg3812\">https://doi.org/10.1126/science.adg3812</a>."},"abstract":[{"text":"Quantum entanglement is a key resource in currently developed quantum technologies. Sharing this fragile property between superconducting microwave circuits and optical or atomic systems would enable new functionalities, but this has been hindered by an energy scale mismatch of >104 and the resulting mutually imposed loss and noise. In this work, we created and verified entanglement between microwave and optical fields in a millikelvin environment. Using an optically pulsed superconducting electro-optical device, we show entanglement between propagating microwave and optical fields in the continuous variable domain. This achievement not only paves the way for entanglement between superconducting circuits and telecom wavelength light, but also has wide-ranging implications for hybrid quantum networks in the context of modularization, scaling, sensing, and cross-platform verification.","lang":"eng"}],"pmid":1,"type":"journal_article","quality_controlled":"1","title":"Entangling microwaves with light","author":[{"first_name":"Rishabh","orcid":"0000-0001-6264-2162","full_name":"Sahu, Rishabh","last_name":"Sahu","id":"47D26E34-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0003-4345-4267","full_name":"Qiu, Liu","last_name":"Qiu","id":"45e99c0d-1eb1-11eb-9b96-ed8ab2983cac","first_name":"Liu"},{"orcid":"0000-0001-9868-2166","id":"29705398-F248-11E8-B48F-1D18A9856A87","full_name":"Hease, William J","last_name":"Hease","first_name":"William J"},{"last_name":"Arnold","full_name":"Arnold, Georg M","id":"3770C838-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1397-7876","first_name":"Georg M"},{"full_name":"Minoguchi, Y.","last_name":"Minoguchi","first_name":"Y."},{"first_name":"P.","last_name":"Rabl","full_name":"Rabl, P."},{"id":"4B591CBA-F248-11E8-B48F-1D18A9856A87","full_name":"Fink, Johannes M","last_name":"Fink","orcid":"0000-0001-8112-028X","first_name":"Johannes M"}],"date_updated":"2026-04-15T06:39:33Z","related_material":{"record":[{"status":"public","id":"13122","relation":"research_data"}],"link":[{"relation":"press_release","url":"https://ista.ac.at/en/news/wiring-up-quantum-circuits-with-light/","description":"News on ISTA Website"}]},"page":"718-721","language":[{"iso":"eng"}],"status":"public","article_processing_charge":"No","oa_version":"Preprint","keyword":["Multidisciplinary"],"isi":1,"publication":"Science","arxiv":1,"project":[{"call_identifier":"H2020","_id":"26336814-B435-11E9-9278-68D0E5697425","name":"A Fiber Optic Transceiver for Superconducting Qubits","grant_number":"758053"},{"name":"Quantum Local Area Networks with Superconducting Qubits","_id":"9B868D20-BA93-11EA-9121-9846C619BF3A","grant_number":"899354","call_identifier":"H2020"},{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"},{"_id":"237CBA6C-32DE-11EA-91FC-C7463DDC885E","name":"Quantum readout techniques and technologies","grant_number":"862644","call_identifier":"H2020"},{"_id":"2671EB66-B435-11E9-9278-68D0E5697425","name":"Coherent on-chip conversion of superconducting qubit signals from microwaves to optical frequencies"},{"_id":"bdb108fd-d553-11ed-ba76-83dc74a9864f","name":"QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration of Superconducting Quantum Circuits","grant_number":"F07105"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"day":"18","doi":"10.1126/science.adg3812","date_published":"2023-05-18T00:00:00Z","intvolume":"       380","article_type":"original","year":"2023","publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"acknowledgement":"This work was supported by the European Research Council (grant no. 758053, ERC StG QUNNECT) and the European Union’s Horizon 2020 Research and Innovation Program (grant no. 899354, FETopen SuperQuLAN). L.Q. acknowledges generous support from the ISTFELLOW program. W.H. is the recipient of an ISTplus postdoctoral fellowship with funding from the European Union’s Horizon 2020 Research and Innovation Program (Marie Sklodowska-Curie grant no. 754411). G.A. is the recipient of a DOC fellowship of the Austrian Academy of Sciences at IST Austria. J.M.F. acknowledges support from the Austrian Science Fund (FWF) through BeyondC (grant no. F7105) and the European Union’s Horizon 2020 Research and Innovation Program (grant no. 862644, FETopen QUARTET).","ec_funded":1},{"keyword":["Multidisciplinary"],"oa_version":"Published Version","has_accepted_license":"1","article_processing_charge":"No","file_date_updated":"2022-08-08T07:42:09Z","language":[{"iso":"eng"}],"status":"public","date_updated":"2025-05-14T11:01:00Z","title":"RALF1 peptide triggers biphasic root growth inhibition upstream of auxin biosynthesis","author":[{"id":"367EF8FA-F248-11E8-B48F-1D18A9856A87","full_name":"Li, Lanxin","last_name":"Li","orcid":"0000-0002-5607-272X","first_name":"Lanxin"},{"full_name":"Chen, Huihuang","last_name":"Chen","id":"83c96512-15b2-11ec-abd3-b7eede36184f","first_name":"Huihuang"},{"last_name":"Alotaibi","full_name":"Alotaibi, Saqer S.","first_name":"Saqer S."},{"first_name":"Aleš","last_name":"Pěnčík","full_name":"Pěnčík, Aleš"},{"id":"45F536D2-F248-11E8-B48F-1D18A9856A87","full_name":"Adamowski, Maciek","last_name":"Adamowski","orcid":"0000-0001-6463-5257","first_name":"Maciek"},{"full_name":"Novák, Ondřej","last_name":"Novák","first_name":"Ondřej"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří"}],"year":"2022","article_type":"original","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"acknowledgement":"We thank Sarah M. Assmann, Kris Vissenberg, and Nadine Paris for kindly sharing seeds; Matyáš Fendrych for initiating this project and providing constant support; Lukas Fiedler for revising the manuscript; and Huibin Han and Arseny Savin for contributing to genotyping. This work was supported by the Austrian Science Fund (FWF) I 3630-B25 (to J.F.) and the Doctoral Fellowship Progrmme of the Austrian Academy of Sciences (to L.L.) We also acknowledge Taif University Researchers Supporting Project TURSP-HC2021/02 and funding “Plants as a tool for sustainable global development (no. CZ.02.1.01/0.0/0.0/16_019/0000827).”","article_number":"e2121058119","date_published":"2022-07-25T00:00:00Z","intvolume":"       119","oa":1,"file":[{"access_level":"open_access","date_created":"2022-08-08T07:42:09Z","success":1,"file_name":"2022_PNAS_Li.pdf","creator":"dernst","file_size":2506262,"content_type":"application/pdf","checksum":"ae6f19b0d9efba6687f9e4dc1bab1d6e","relation":"main_file","date_updated":"2022-08-08T07:42:09Z","file_id":"11747"}],"doi":"10.1073/pnas.2121058119","day":"25","ddc":["580"],"project":[{"call_identifier":"FWF","grant_number":"I03630","_id":"26538374-B435-11E9-9278-68D0E5697425","name":"Molecular mechanisms of endocytic cargo recognition in plants"},{"name":"A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated Rapid Growth Inhibition in Arabidopsis Root","_id":"26B4D67E-B435-11E9-9278-68D0E5697425","grant_number":"25351"}],"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"publication":"Proceedings of the National Academy of Sciences of the United States of America","external_id":{"pmid":["35878023"],"isi":["000881496900002"]},"date_created":"2022-08-04T20:06:49Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png"},"publication_status":"published","issue":"31","scopus_import":"1","month":"07","_id":"11723","quality_controlled":"1","citation":{"chicago":"Li, Lanxin, Huihuang Chen, Saqer S. Alotaibi, Aleš Pěnčík, Maciek Adamowski, Ondřej Novák, and Jiří Friml. “RALF1 Peptide Triggers Biphasic Root Growth Inhibition Upstream of Auxin Biosynthesis.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2022. <a href=\"https://doi.org/10.1073/pnas.2121058119\">https://doi.org/10.1073/pnas.2121058119</a>.","ista":"Li L, Chen H, Alotaibi SS, Pěnčík A, Adamowski M, Novák O, Friml J. 2022. RALF1 peptide triggers biphasic root growth inhibition upstream of auxin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 119(31), e2121058119.","mla":"Li, Lanxin, et al. “RALF1 Peptide Triggers Biphasic Root Growth Inhibition Upstream of Auxin Biosynthesis.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 119, no. 31, e2121058119, National Academy of Sciences, 2022, doi:<a href=\"https://doi.org/10.1073/pnas.2121058119\">10.1073/pnas.2121058119</a>.","ama":"Li L, Chen H, Alotaibi SS, et al. RALF1 peptide triggers biphasic root growth inhibition upstream of auxin biosynthesis. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2022;119(31). doi:<a href=\"https://doi.org/10.1073/pnas.2121058119\">10.1073/pnas.2121058119</a>","ieee":"L. Li <i>et al.</i>, “RALF1 peptide triggers biphasic root growth inhibition upstream of auxin biosynthesis,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 119, no. 31. National Academy of Sciences, 2022.","apa":"Li, L., Chen, H., Alotaibi, S. S., Pěnčík, A., Adamowski, M., Novák, O., &#38; Friml, J. (2022). RALF1 peptide triggers biphasic root growth inhibition upstream of auxin biosynthesis. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2121058119\">https://doi.org/10.1073/pnas.2121058119</a>","short":"L. Li, H. Chen, S.S. Alotaibi, A. Pěnčík, M. Adamowski, O. Novák, J. Friml, Proceedings of the National Academy of Sciences of the United States of America 119 (2022)."},"type":"journal_article","abstract":[{"lang":"eng","text":"Plant cell growth responds rapidly to various stimuli, adapting architecture to environmental changes. Two major endogenous signals regulating growth are the phytohormone auxin and the secreted peptides rapid alkalinization factors (RALFs). Both trigger very rapid cellular responses and also exert long-term effects [Du et al., Annu. Rev. Plant Biol. 71, 379–402 (2020); Blackburn et al., Plant Physiol. 182, 1657–1666 (2020)]. However, the way, in which these distinct signaling pathways converge to regulate growth, remains unknown. Here, using vertical confocal microscopy combined with a microfluidic chip, we addressed the mechanism of RALF action on growth. We observed correlation between RALF1-induced rapid Arabidopsis thaliana root growth inhibition and apoplast alkalinization during the initial phase of the response, and revealed that RALF1 reversibly inhibits primary root growth through apoplast alkalinization faster than within 1 min. This rapid apoplast alkalinization was the result of RALF1-induced net H+ influx and was mediated by the receptor FERONIA (FER). Furthermore, we investigated the cross-talk between RALF1 and the auxin signaling pathways during root growth regulation. The results showed that RALF-FER signaling triggered auxin signaling with a delay of approximately 1 h by up-regulating auxin biosynthesis, thus contributing to sustained RALF1-induced growth inhibition. This biphasic RALF1 action on growth allows plants to respond rapidly to environmental stimuli and also reprogram growth and development in the long term."}],"pmid":1,"corr_author":"1","publisher":"National Academy of Sciences","department":[{"_id":"GradSch"},{"_id":"JiFr"}],"volume":119},{"status":"public","language":[{"iso":"eng"}],"article_processing_charge":"No","has_accepted_license":"1","file_date_updated":"2022-08-26T11:51:40Z","title":"A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory","author":[{"id":"43DF3136-F248-11E8-B48F-1D18A9856A87","last_name":"Ben Simon","full_name":"Ben Simon, Yoav","first_name":"Yoav"},{"full_name":"Käfer, Karola","last_name":"Käfer","id":"2DAA49AA-F248-11E8-B48F-1D18A9856A87","first_name":"Karola"},{"orcid":"0000-0002-2340-7431","id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","last_name":"Velicky","full_name":"Velicky, Philipp","first_name":"Philipp"},{"orcid":"0000-0002-5193-4036","last_name":"Csicsvari","full_name":"Csicsvari, Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","first_name":"Jozsef L"},{"first_name":"Johann G","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","full_name":"Danzl, Johann G","last_name":"Danzl","orcid":"0000-0001-8559-3973"},{"orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M"}],"date_updated":"2025-06-12T06:10:44Z","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"oa_version":"Published Version","project":[{"call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","grant_number":"692692"},{"_id":"265CB4D0-B435-11E9-9278-68D0E5697425","name":"Optical control of synaptic function via adhesion molecules","grant_number":"I03600","call_identifier":"FWF"},{"call_identifier":"FWF","grant_number":"Z00312","name":"Synaptic communication in neuronal microcircuits","_id":"25C5A090-B435-11E9-9278-68D0E5697425"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"isi":1,"publication":"Nature Communications","article_number":"4826","acknowledged_ssus":[{"_id":"Bio"},{"_id":"SSU"}],"year":"2022","publication_identifier":{"issn":["2041-1723"]},"article_type":"original","acknowledgement":"We thank F. Marr and A. Schlögl for technical assistance, E. Kralli-Beller for manuscript editing, as well as C. Sommer and the Imaging and Optics Facility of the Institute of Science and Technology Austria (ISTA) for image analysis scripts and microscopy support. We extend our gratitude to J. Wallenschus and D. Rangel Guerrero for technical assistance acquiring single-unit data and I. Gridchyn for help with single-unit clustering. Finally, we also thank B. Suter for discussions, A. Saunders, M. Jösch, and H. Monyer for critically reading earlier versions of the manuscript, C. Petersen for sharing clearing protocols, and the Scientific Service Units of ISTA for efficient support. This project was funded by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (ERC advanced grant No 692692 to P.J.) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award for P.J. and I3600-B27 for J.G.D. and P.V.).","ec_funded":1,"file":[{"file_size":5910357,"creator":"dernst","file_name":"2022_NatureCommunications_BenSimon.pdf","success":1,"date_created":"2022-08-26T11:51:40Z","access_level":"open_access","file_id":"11990","date_updated":"2022-08-26T11:51:40Z","relation":"main_file","content_type":"application/pdf","checksum":"405936d9e4d33625d80c093c9713a91f"}],"oa":1,"day":"16","doi":"10.1038/s41467-022-32559-8","date_published":"2022-08-16T00:00:00Z","intvolume":"        13","month":"08","scopus_import":"1","_id":"11951","external_id":{"isi":["000841396400008"],"pmid":["35974109"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","date_created":"2022-08-24T08:25:50Z","publisher":"Springer Nature","corr_author":"1","volume":13,"department":[{"_id":"JoCs"},{"_id":"PeJo"},{"_id":"JoDa"}],"citation":{"ieee":"Y. Ben Simon, K. Käfer, P. Velicky, J. L. Csicsvari, J. G. Danzl, and P. M. Jonas, “A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","ama":"Ben Simon Y, Käfer K, Velicky P, Csicsvari JL, Danzl JG, Jonas PM. A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-32559-8\">10.1038/s41467-022-32559-8</a>","apa":"Ben Simon, Y., Käfer, K., Velicky, P., Csicsvari, J. L., Danzl, J. G., &#38; Jonas, P. M. (2022). A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-32559-8\">https://doi.org/10.1038/s41467-022-32559-8</a>","mla":"Ben Simon, Yoav, et al. “A Direct Excitatory Projection from Entorhinal Layer 6b Neurons to the Hippocampus Contributes to Spatial Coding and Memory.” <i>Nature Communications</i>, vol. 13, 4826, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-32559-8\">10.1038/s41467-022-32559-8</a>.","ista":"Ben Simon Y, Käfer K, Velicky P, Csicsvari JL, Danzl JG, Jonas PM. 2022. A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory. Nature Communications. 13, 4826.","chicago":"Ben Simon, Yoav, Karola Käfer, Philipp Velicky, Jozsef L Csicsvari, Johann G Danzl, and Peter M Jonas. “A Direct Excitatory Projection from Entorhinal Layer 6b Neurons to the Hippocampus Contributes to Spatial Coding and Memory.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-32559-8\">https://doi.org/10.1038/s41467-022-32559-8</a>.","short":"Y. Ben Simon, K. Käfer, P. Velicky, J.L. Csicsvari, J.G. Danzl, P.M. Jonas, Nature Communications 13 (2022)."},"type":"journal_article","abstract":[{"lang":"eng","text":"The mammalian hippocampal formation (HF) plays a key role in several higher brain functions, such as spatial coding, learning and memory. Its simple circuit architecture is often viewed as a trisynaptic loop, processing input originating from the superficial layers of the entorhinal cortex (EC) and sending it back to its deeper layers. Here, we show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the HF and receive input from the CA1, thalamus and claustrum. Furthermore, their output is characterized by unique slow-decaying excitatory postsynaptic currents capable of driving plateau-like potentials in their postsynaptic targets. Optogenetic inhibition of the EC-6b pathway affects spatial coding in CA1 pyramidal neurons, while cell ablation impairs not only acquisition of new spatial memories, but also degradation of previously acquired ones. Our results provide evidence of a functional role for cortical layer 6b neurons in the adult brain."}],"pmid":1,"quality_controlled":"1"},{"quality_controlled":"1","type":"journal_article","abstract":[{"lang":"eng","text":"Germline determination is essential for species survival and evolution in multicellular organisms. In most flowering plants, formation of the female germline is initiated with specification of one megaspore mother cell (MMC) in each ovule; however, the molecular mechanism underlying this key event remains unclear. Here we report that spatially restricted auxin signaling promotes MMC fate in Arabidopsis. Our results show that the microRNA160 (miR160) targeted gene ARF17 (AUXIN RESPONSE FACTOR17) is required for promoting MMC specification by genetically interacting with the SPL/NZZ (SPOROCYTELESS/NOZZLE) gene. Alterations of auxin signaling cause formation of supernumerary MMCs in an ARF17- and SPL/NZZ-dependent manner. Furthermore, miR160 and ARF17 are indispensable for attaining a normal auxin maximum at the ovule apex via modulating the expression domain of PIN1 (PIN-FORMED1) auxin transporter. Our findings elucidate the mechanism by which auxin signaling promotes the acquisition of female germline cell fate in plants."}],"pmid":1,"citation":{"ama":"Huang J, Zhao L, Malik S, et al. Specification of female germline by microRNA orchestrated auxin signaling in Arabidopsis. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-34723-6\">10.1038/s41467-022-34723-6</a>","ieee":"J. Huang <i>et al.</i>, “Specification of female germline by microRNA orchestrated auxin signaling in Arabidopsis,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","apa":"Huang, J., Zhao, L., Malik, S., Gentile, B. R., Xiong, V., Arazi, T., … Zhao, D. (2022). Specification of female germline by microRNA orchestrated auxin signaling in Arabidopsis. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-34723-6\">https://doi.org/10.1038/s41467-022-34723-6</a>","mla":"Huang, Jian, et al. “Specification of Female Germline by MicroRNA Orchestrated Auxin Signaling in Arabidopsis.” <i>Nature Communications</i>, vol. 13, 6960, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-34723-6\">10.1038/s41467-022-34723-6</a>.","ista":"Huang J, Zhao L, Malik S, Gentile BR, Xiong V, Arazi T, Owen HA, Friml J, Zhao D. 2022. Specification of female germline by microRNA orchestrated auxin signaling in Arabidopsis. Nature Communications. 13, 6960.","chicago":"Huang, Jian, Lei Zhao, Shikha Malik, Benjamin R. Gentile, Va Xiong, Tzahi Arazi, Heather A. Owen, Jiří Friml, and Dazhong Zhao. “Specification of Female Germline by MicroRNA Orchestrated Auxin Signaling in Arabidopsis.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-34723-6\">https://doi.org/10.1038/s41467-022-34723-6</a>.","short":"J. Huang, L. Zhao, S. Malik, B.R. Gentile, V. Xiong, T. Arazi, H.A. Owen, J. Friml, D. Zhao, Nature Communications 13 (2022)."},"department":[{"_id":"JiFr"}],"volume":13,"publisher":"Springer Nature","date_created":"2023-01-12T12:02:41Z","publication_status":"published","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"external_id":{"isi":["000884426700001"],"pmid":["36379956"]},"_id":"12130","scopus_import":"1","month":"11","intvolume":"        13","date_published":"2022-11-15T00:00:00Z","doi":"10.1038/s41467-022-34723-6","day":"15","file":[{"file_size":3375249,"creator":"dernst","file_name":"2022_NatureCommunications_Huang.pdf","success":1,"date_created":"2023-01-23T11:17:33Z","access_level":"open_access","file_id":"12346","date_updated":"2023-01-23T11:17:33Z","relation":"main_file","content_type":"application/pdf","checksum":"233922a7b9507d9d48591e6799e4526e"}],"oa":1,"year":"2022","publication_identifier":{"eissn":["2041-1723"]},"article_type":"original","acknowledgement":"We thank A. Cheung,W. Lukowitz, V.Walbot, D.Weijers, and R. Yadegari for critically reading the manuscript; E. Xiong and G. Zhang for preparing some experiments, T. Schuck, J. Gonnering, and P. Engevold for plant care, the Arabidopsis Biological Resource Center (ABRC) for ARF10,ARF16, ARF17, EMS1,MIR160a BAC clones and cDNAs, the SALK_090804 seed, T. Nakagawa for pGBW vectors, Y. Zhao for the YUC1 cDNA, Q. Chen for the pHEE401E vector, R. Yadegari for pAT5G01860::n1GFP, pAT5G45980:n1GFP, pAT5G50490::n1GFP, pAT5G56200:n1GFP vectors, and D.Weijers for the pGreenII KAN SV40-3×GFP and R2D2 vectors, W. Yang for the splmutant, Y. Qin for the pKNU::KNU-VENUS vector and seed, G. Tang for the STTM160/160-48 vector, and L. Colombo for pPIN1::PIN1-GFP spl and pin1-5 seeds. This work was supported by the US National Science Foundation (NSF)-Israel Binational Science Foundation (BSF) research grant to D.Z. (IOS-1322796) and T.A. (2012756). D.Z. also\r\ngratefully acknowledges supports of the Shaw Scientist Award from the Greater Milwaukee Foundation, USDA National Institute of Food and Agriculture (NIFA, 2022-67013-36294), the UWM Discovery and Innovation Grant, the Bradley Catalyst Award from the UWM Research\r\nFoundation, and WiSys and UW System Applied Research Funding Programs.","article_number":"6960","publication":"Nature Communications","isi":1,"ddc":["580"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"date_updated":"2025-07-08T09:01:02Z","author":[{"last_name":"Huang","full_name":"Huang, Jian","first_name":"Jian"},{"first_name":"Lei","last_name":"Zhao","full_name":"Zhao, Lei"},{"first_name":"Shikha","last_name":"Malik","full_name":"Malik, Shikha"},{"last_name":"Gentile","full_name":"Gentile, Benjamin R.","first_name":"Benjamin R."},{"first_name":"Va","last_name":"Xiong","full_name":"Xiong, Va"},{"first_name":"Tzahi","full_name":"Arazi, Tzahi","last_name":"Arazi"},{"full_name":"Owen, Heather A.","last_name":"Owen","first_name":"Heather A."},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","last_name":"Friml","orcid":"0000-0002-8302-7596","first_name":"Jiří"},{"first_name":"Dazhong","full_name":"Zhao, Dazhong","last_name":"Zhao"}],"title":"Specification of female germline by microRNA orchestrated auxin signaling in Arabidopsis","file_date_updated":"2023-01-23T11:17:33Z","article_processing_charge":"No","has_accepted_license":"1","language":[{"iso":"eng"}],"status":"public"},{"volume":13,"department":[{"_id":"StFr"}],"publisher":"Springer Nature","corr_author":"1","citation":{"short":"C. Prehal, J.-M. von Mentlen, S. Drvarič Talian, A. Vizintin, R. Dominko, H. Amenitsch, L. Porcar, S.A. Freunberger, V. Wood, Nature Communications 13 (2022).","ieee":"C. Prehal <i>et al.</i>, “On the nanoscale structural evolution of solid discharge products in lithium-sulfur batteries using operando scattering,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","ama":"Prehal C, von Mentlen J-M, Drvarič Talian S, et al. On the nanoscale structural evolution of solid discharge products in lithium-sulfur batteries using operando scattering. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-33931-4\">10.1038/s41467-022-33931-4</a>","apa":"Prehal, C., von Mentlen, J.-M., Drvarič Talian, S., Vizintin, A., Dominko, R., Amenitsch, H., … Wood, V. (2022). On the nanoscale structural evolution of solid discharge products in lithium-sulfur batteries using operando scattering. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-33931-4\">https://doi.org/10.1038/s41467-022-33931-4</a>","ista":"Prehal C, von Mentlen J-M, Drvarič Talian S, Vizintin A, Dominko R, Amenitsch H, Porcar L, Freunberger SA, Wood V. 2022. On the nanoscale structural evolution of solid discharge products in lithium-sulfur batteries using operando scattering. Nature Communications. 13, 6326.","chicago":"Prehal, Christian, Jean-Marc von Mentlen, Sara Drvarič Talian, Alen Vizintin, Robert Dominko, Heinz Amenitsch, Lionel Porcar, Stefan Alexander Freunberger, and Vanessa Wood. “On the Nanoscale Structural Evolution of Solid Discharge Products in Lithium-Sulfur Batteries Using Operando Scattering.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-33931-4\">https://doi.org/10.1038/s41467-022-33931-4</a>.","mla":"Prehal, Christian, et al. “On the Nanoscale Structural Evolution of Solid Discharge Products in Lithium-Sulfur Batteries Using Operando Scattering.” <i>Nature Communications</i>, vol. 13, 6326, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-33931-4\">10.1038/s41467-022-33931-4</a>."},"type":"journal_article","pmid":1,"abstract":[{"text":"The inadequate understanding of the mechanisms that reversibly convert molecular sulfur (S) into lithium sulfide (Li<jats:sub>2</jats:sub>S) via soluble polysulfides (PSs) formation impedes the development of high-performance lithium-sulfur (Li-S) batteries with non-aqueous electrolyte solutions. Here, we use operando small and wide angle X-ray scattering and operando small angle neutron scattering (SANS) measurements to track the nucleation, growth and dissolution of solid deposits from atomic to sub-micron scales during real-time Li-S cell operation. In particular, stochastic modelling based on the SANS data allows quantifying the nanoscale phase evolution during battery cycling. We show that next to nano-crystalline Li<jats:sub>2</jats:sub>S the deposit comprises solid short-chain PSs particles. The analysis of the experimental data suggests that initially, Li<jats:sub>2</jats:sub>S<jats:sub>2</jats:sub> precipitates from the solution and then is partially converted via solid-state electroreduction to Li<jats:sub>2</jats:sub>S. We further demonstrate that mass transport, rather than electron transport through a thin passivating film, limits the discharge capacity and rate performance in Li-S cells.","lang":"eng"}],"quality_controlled":"1","_id":"12208","month":"10","scopus_import":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","date_created":"2023-01-16T09:45:09Z","external_id":{"isi":["000871563700006"],"pmid":["36280671"]},"isi":1,"publication":"Nature Communications","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","ddc":["540"],"oa":1,"file":[{"access_level":"open_access","creator":"dernst","file_size":4216931,"date_created":"2023-01-27T07:19:11Z","success":1,"file_name":"2022_NatureCommunications_Prehal.pdf","checksum":"5034336dbf0f860030ef745c08df9e0e","content_type":"application/pdf","relation":"main_file","date_updated":"2023-01-27T07:19:11Z","file_id":"12411"}],"doi":"10.1038/s41467-022-33931-4","day":"24","date_published":"2022-10-24T00:00:00Z","intvolume":"        13","article_number":"6326","publication_identifier":{"issn":["2041-1723"]},"article_type":"original","acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant NanoEvolution, grant agreement No 894042. The authors acknowledge the CERIC-ERIC Consortium for the access to the Austrian SAXS beamline and TU Graz for support through the Lead Project LP-03.\r\nLikewise, the use of SOMAPP Lab, a core facility supported by the Austrian Federal Ministry of Education, Science and Research, the Graz University of Technology, the University of Graz, and Anton Paar GmbH is acknowledged. In addition, the authors acknowledge access to the D-22SANS beamline at the ILL neutron source. Electron microscopy measurements were performed at the Scientific Scenter for Optical and Electron Microscopy (ScopeM) of the Swiss Federal Institute of Technology. C.P. and J.M.M. thank A. Senol for her support with the SANS\r\nbeamtime preparation. S.D.T, A.V. and R.D. acknowledge the financial support by the Slovenian Research Agency (ARRS) research core funding P2-0393 and P2-0423. Furthermore, A.V. acknowledge the funding from the Slovenian Research Agency, research project Z2−1863.\r\nS.A.F. is indebted to IST Austria for support. ","year":"2022","author":[{"first_name":"Christian","last_name":"Prehal","full_name":"Prehal, Christian"},{"full_name":"von Mentlen, Jean-Marc","last_name":"von Mentlen","first_name":"Jean-Marc"},{"first_name":"Sara","full_name":"Drvarič Talian, Sara","last_name":"Drvarič Talian"},{"full_name":"Vizintin, Alen","last_name":"Vizintin","first_name":"Alen"},{"first_name":"Robert","full_name":"Dominko, Robert","last_name":"Dominko"},{"first_name":"Heinz","last_name":"Amenitsch","full_name":"Amenitsch, Heinz"},{"full_name":"Porcar, Lionel","last_name":"Porcar","first_name":"Lionel"},{"orcid":"0000-0003-2902-5319","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","last_name":"Freunberger","full_name":"Freunberger, Stefan Alexander","first_name":"Stefan Alexander"},{"first_name":"Vanessa","full_name":"Wood, Vanessa","last_name":"Wood"}],"title":"On the nanoscale structural evolution of solid discharge products in lithium-sulfur batteries using operando scattering","date_updated":"2024-10-09T21:03:47Z","status":"public","language":[{"iso":"eng"}],"has_accepted_license":"1","article_processing_charge":"No","file_date_updated":"2023-01-27T07:19:11Z","oa_version":"Published Version","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"]},{"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"oa_version":"Published Version","file_date_updated":"2023-01-27T08:14:48Z","has_accepted_license":"1","article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","related_material":{"record":[{"status":"public","id":"13068","relation":"research_data"}]},"date_updated":"2025-06-11T13:53:55Z","author":[{"first_name":"S.","full_name":"Randriamanantsoa, S.","last_name":"Randriamanantsoa"},{"first_name":"A.","last_name":"Papargyriou","full_name":"Papargyriou, A."},{"first_name":"H. C.","full_name":"Maurer, H. C.","last_name":"Maurer"},{"full_name":"Peschke, K.","last_name":"Peschke","first_name":"K."},{"first_name":"M.","last_name":"Schuster","full_name":"Schuster, M."},{"first_name":"G.","last_name":"Zecchin","full_name":"Zecchin, G."},{"first_name":"K.","last_name":"Steiger","full_name":"Steiger, K."},{"first_name":"R.","full_name":"Öllinger, R.","last_name":"Öllinger"},{"full_name":"Saur, D.","last_name":"Saur","first_name":"D."},{"full_name":"Scheel, C.","last_name":"Scheel","first_name":"C."},{"full_name":"Rad, R.","last_name":"Rad","first_name":"R."},{"first_name":"Edouard B","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","last_name":"Hannezo"},{"last_name":"Reichert","full_name":"Reichert, M.","first_name":"M."},{"first_name":"A. R.","last_name":"Bausch","full_name":"Bausch, A. R."}],"title":"Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids","ec_funded":1,"acknowledgement":"A.R.B. acknowledges the financial support of the European Research Council (ERC) through the funding of the grant Principles of Integrin Mechanics and Adhesion (PoINT) and the German Research Foundation (DFG, SFB 1032, project ID 201269156). E.H. was supported by the European Union (European Research Council Starting Grant 851288). D.S., M.R., and R.R. acknowledge the support by the German Research Foundation (DFG, SFB1321 Modeling and Targeting Pancreatic Cancer, Project S01, project ID 329628492). C.S. and M.R. acknowledge the support by the German Research Foundation (DFG, SFB1321 Modeling and Targeting Pancreatic Cancer, Project 12, project ID 329628492). M.R. was supported by the German Research Foundation (DFG RE 3723/4-1). A.P. and M.R. were supported by the German Cancer Aid (Max-Eder Program 111273 and 70114328).\r\nOpen Access funding enabled and organized by Projekt DEAL.","publication_identifier":{"issn":["2041-1723"]},"article_type":"original","year":"2022","article_number":"5219","intvolume":"        13","date_published":"2022-09-05T00:00:00Z","day":"05","doi":"10.1038/s41467-022-32806-y","oa":1,"file":[{"access_level":"open_access","file_name":"2022_NatureCommunications_Randriamanantsoa.pdf","date_created":"2023-01-27T08:14:48Z","success":1,"file_size":22645149,"creator":"dernst","relation":"main_file","content_type":"application/pdf","checksum":"295261b5172274fd5b8f85a6a6058828","file_id":"12416","date_updated":"2023-01-27T08:14:48Z"}],"ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"H2020","grant_number":"851288","name":"Design Principles of Branching Morphogenesis","_id":"05943252-7A3F-11EA-A408-12923DDC885E"}],"publication":"Nature Communications","isi":1,"external_id":{"pmid":["36064947"],"isi":["000850348400025"]},"date_created":"2023-01-16T09:46:53Z","publication_status":"published","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"scopus_import":"1","month":"09","_id":"12217","quality_controlled":"1","abstract":[{"text":"The development dynamics and self-organization of glandular branched epithelia is of utmost importance for our understanding of diverse processes ranging from normal tissue growth to the growth of cancerous tissues. Using single primary murine pancreatic ductal adenocarcinoma (PDAC) cells embedded in a collagen matrix and adapted media supplementation, we generate organoids that self-organize into highly branched structures displaying a seamless lumen connecting terminal end buds, replicating in vivo PDAC architecture. We identify distinct morphogenesis phases, each characterized by a unique pattern of cell invasion, matrix deformation, protein expression, and respective molecular dependencies. We propose a minimal theoretical model of a branching and proliferating tissue, capturing the dynamics of the first phases. Observing the interaction of morphogenesis, mechanical environment and gene expression in vitro sets a benchmark for the understanding of self-organization processes governing complex organoid structure formation processes and branching morphogenesis.","lang":"eng"}],"type":"journal_article","pmid":1,"citation":{"short":"S. Randriamanantsoa, A. Papargyriou, H.C. Maurer, K. Peschke, M. Schuster, G. Zecchin, K. Steiger, R. Öllinger, D. Saur, C. Scheel, R. Rad, E.B. Hannezo, M. Reichert, A.R. Bausch, Nature Communications 13 (2022).","ama":"Randriamanantsoa S, Papargyriou A, Maurer HC, et al. Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-32806-y\">10.1038/s41467-022-32806-y</a>","apa":"Randriamanantsoa, S., Papargyriou, A., Maurer, H. C., Peschke, K., Schuster, M., Zecchin, G., … Bausch, A. R. (2022). Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-32806-y\">https://doi.org/10.1038/s41467-022-32806-y</a>","ieee":"S. Randriamanantsoa <i>et al.</i>, “Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","chicago":"Randriamanantsoa, S., A. Papargyriou, H. C. Maurer, K. Peschke, M. Schuster, G. Zecchin, K. Steiger, et al. “Spatiotemporal Dynamics of Self-Organized Branching in Pancreas-Derived Organoids.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-32806-y\">https://doi.org/10.1038/s41467-022-32806-y</a>.","ista":"Randriamanantsoa S, Papargyriou A, Maurer HC, Peschke K, Schuster M, Zecchin G, Steiger K, Öllinger R, Saur D, Scheel C, Rad R, Hannezo EB, Reichert M, Bausch AR. 2022. Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. Nature Communications. 13, 5219.","mla":"Randriamanantsoa, S., et al. “Spatiotemporal Dynamics of Self-Organized Branching in Pancreas-Derived Organoids.” <i>Nature Communications</i>, vol. 13, 5219, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-32806-y\">10.1038/s41467-022-32806-y</a>."},"publisher":"Springer Nature","department":[{"_id":"EdHa"}],"volume":13},{"_id":"12225","scopus_import":"1","month":"06","date_created":"2023-01-16T09:48:30Z","publication_status":"published","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"external_id":{"isi":["000805561200024"],"pmid":["35654942"]},"department":[{"_id":"TiVo"}],"volume":12,"publisher":"Springer Nature","quality_controlled":"1","abstract":[{"text":"In social networks, users often engage with like-minded peers. This selective exposure to opinions might result in echo chambers, i.e., political fragmentation and social polarization of user interactions. When echo chambers form, opinions have a bimodal distribution with two peaks on opposite sides. In certain issues, where either extreme positions contain a degree of misinformation, neutral consensus is preferable for promoting discourse. In this paper, we use an opinion dynamics model that naturally forms echo chambers in order to find a feedback mechanism that bridges these communities and leads to a neutral consensus. We introduce the <jats:italic>random dynamical nudge</jats:italic> (RDN), which presents each agent with input from a random selection of other agents’ opinions and does not require surveillance of every person’s opinions. Our computational results in two different models suggest that the RDN leads to a unimodal distribution of opinions centered around the neutral consensus. Furthermore, the RDN is effective both for preventing the formation of echo chambers and also for depolarizing existing echo chambers. Due to the simple and robust nature of the RDN, social media networks might be able to implement a version of this self-feedback mechanism, when appropriate, to prevent the segregation of online communities on complex social issues.","lang":"eng"}],"type":"journal_article","pmid":1,"citation":{"mla":"Currin, Christopher, et al. “Depolarization of Echo Chambers by Random Dynamical Nudge.” <i>Scientific Reports</i>, vol. 12, 9234, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41598-022-12494-w\">10.1038/s41598-022-12494-w</a>.","chicago":"Currin, Christopher, Sebastián Vallejo Vera, and Ali Khaledi-Nasab. “Depolarization of Echo Chambers by Random Dynamical Nudge.” <i>Scientific Reports</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41598-022-12494-w\">https://doi.org/10.1038/s41598-022-12494-w</a>.","ista":"Currin C, Vera SV, Khaledi-Nasab A. 2022. Depolarization of echo chambers by random dynamical nudge. Scientific Reports. 12, 9234.","ieee":"C. Currin, S. V. Vera, and A. Khaledi-Nasab, “Depolarization of echo chambers by random dynamical nudge,” <i>Scientific Reports</i>, vol. 12. Springer Nature, 2022.","ama":"Currin C, Vera SV, Khaledi-Nasab A. Depolarization of echo chambers by random dynamical nudge. <i>Scientific Reports</i>. 2022;12. doi:<a href=\"https://doi.org/10.1038/s41598-022-12494-w\">10.1038/s41598-022-12494-w</a>","apa":"Currin, C., Vera, S. V., &#38; Khaledi-Nasab, A. (2022). Depolarization of echo chambers by random dynamical nudge. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-022-12494-w\">https://doi.org/10.1038/s41598-022-12494-w</a>","short":"C. Currin, S.V. Vera, A. Khaledi-Nasab, Scientific Reports 12 (2022)."},"date_updated":"2023-08-04T09:26:30Z","author":[{"first_name":"Christopher","orcid":"0000-0002-4809-5059","id":"e8321fc5-3091-11eb-8a53-83f309a11ac9","full_name":"Currin, Christopher","last_name":"Currin"},{"full_name":"Vera, Sebastián Vallejo","last_name":"Vera","first_name":"Sebastián Vallejo"},{"first_name":"Ali","last_name":"Khaledi-Nasab","full_name":"Khaledi-Nasab, Ali"}],"title":"Depolarization of echo chambers by random dynamical nudge","file_date_updated":"2023-01-27T08:56:18Z","has_accepted_license":"1","article_processing_charge":"No","status":"public","language":[{"iso":"eng"}],"oa_version":"Published Version","keyword":["Multidisciplinary"],"publication":"Scientific Reports","isi":1,"ddc":["570"],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","intvolume":"        12","date_published":"2022-06-02T00:00:00Z","doi":"10.1038/s41598-022-12494-w","day":"02","oa":1,"file":[{"access_level":"open_access","success":1,"date_created":"2023-01-27T08:56:18Z","file_name":"2022_ScientificReports_Currin.pdf","file_size":3625627,"creator":"dernst","relation":"main_file","checksum":"e024a75f14ce5667795a31e44a259c52","content_type":"application/pdf","file_id":"12418","date_updated":"2023-01-27T08:56:18Z"}],"acknowledgement":"CBC and AKN would like to thank Neuromatch Academy https://www.neuromatchacademy.org for introducing the authors to each other. We thank Dr. Krešimir Josic (University of Houston) , Fabian Baumann (Humboldt University) and Dr. Igor M. Sokolov (Humboldt University) for carefully reading the early versions of the manuscript and providing constructive feedback. CBC is supported by the German Deutscher Akademischer Austauschdienst (DAAD, https://daad.de), the South African National Research Foundation (NRF, https://nrf.ac.za), the University of Cape Town (UCT, https://uct.ac.za), and the NOMIS Foundation through the NOMIS Fellowships at IST Austria program (https://nomisfoundation.ch). SVV appreciate the generosity of Tecnológico de Monterrey for covering the publication fee.","year":"2022","article_type":"original","publication_identifier":{"issn":["2045-2322"]},"article_number":"9234"},{"oa_version":"Published Version","keyword":["Multidisciplinary"],"date_updated":"2023-08-22T07:24:01Z","author":[{"last_name":"Svoboda","full_name":"Svoboda, Vít","first_name":"Vít"},{"first_name":"Niraghatam Bhargava","full_name":"Ram, Niraghatam Bhargava","last_name":"Ram"},{"first_name":"Denitsa Rangelova","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva"},{"first_name":"Daniel","last_name":"Zindel","full_name":"Zindel, Daniel"},{"last_name":"Waters","full_name":"Waters, Max D. J.","first_name":"Max D. J."},{"full_name":"Spenger, Benjamin","last_name":"Spenger","first_name":"Benjamin"},{"first_name":"Manuel","full_name":"Ochsner, Manuel","last_name":"Ochsner"},{"full_name":"Herburger, Holger","last_name":"Herburger","first_name":"Holger"},{"first_name":"Jürgen","full_name":"Stohner, Jürgen","last_name":"Stohner"},{"last_name":"Wörner","full_name":"Wörner, Hans Jakob","first_name":"Hans Jakob"}],"title":"Femtosecond photoelectron circular dichroism of chemical reactions","article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","intvolume":"         8","date_published":"2022-07-15T00:00:00Z","doi":"10.1126/sciadv.abq2811","day":"15","oa":1,"article_type":"original","year":"2022","publication_identifier":{"eissn":["2375-2548"]},"article_number":"abq2811","arxiv":1,"publication":"Science Advances","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-08-09T13:08:04Z","publication_status":"published","external_id":{"pmid":["35857523"],"arxiv":["2206.04099"]},"_id":"13992","scopus_import":"1","issue":"28","month":"07","quality_controlled":"1","abstract":[{"lang":"eng","text":"Understanding the chirality of molecular reaction pathways is essential for a broad range of fundamental and applied sciences. However, the current ability to probe chirality on the time scale of primary processes underlying chemical reactions remains very limited. Here, we demonstrate time-resolved photoelectron circular dichroism (TRPECD) with ultrashort circularly polarized vacuum-ultraviolet (VUV) pulses from a tabletop source. We demonstrate the capabilities of VUV-TRPECD by resolving the chirality changes in time during the photodissociation of atomic iodine from two chiral molecules. We identify several general key features of TRPECD, which include the ability to probe dynamical chirality along the complete photochemical reaction path, the sensitivity to the local chirality of the evolving scattering potential, and the influence of electron scattering off dissociating photofragments. Our results are interpreted by comparison with high-level ab-initio calculations of transient PECDs from molecular photoionization calculations. Our experimental and theoretical techniques define a general approach to femtochirality."}],"pmid":1,"type":"journal_article","extern":"1","citation":{"short":"V. Svoboda, N.B. Ram, D.R. Baykusheva, D. Zindel, M.D.J. Waters, B. Spenger, M. Ochsner, H. Herburger, J. Stohner, H.J. Wörner, Science Advances 8 (2022).","mla":"Svoboda, Vít, et al. “Femtosecond Photoelectron Circular Dichroism of Chemical Reactions.” <i>Science Advances</i>, vol. 8, no. 28, abq2811, American Association for the Advancement of Science, 2022, doi:<a href=\"https://doi.org/10.1126/sciadv.abq2811\">10.1126/sciadv.abq2811</a>.","chicago":"Svoboda, Vít, Niraghatam Bhargava Ram, Denitsa Rangelova Baykusheva, Daniel Zindel, Max D. J. Waters, Benjamin Spenger, Manuel Ochsner, Holger Herburger, Jürgen Stohner, and Hans Jakob Wörner. “Femtosecond Photoelectron Circular Dichroism of Chemical Reactions.” <i>Science Advances</i>. American Association for the Advancement of Science, 2022. <a href=\"https://doi.org/10.1126/sciadv.abq2811\">https://doi.org/10.1126/sciadv.abq2811</a>.","ista":"Svoboda V, Ram NB, Baykusheva DR, Zindel D, Waters MDJ, Spenger B, Ochsner M, Herburger H, Stohner J, Wörner HJ. 2022. Femtosecond photoelectron circular dichroism of chemical reactions. Science Advances. 8(28), abq2811.","ama":"Svoboda V, Ram NB, Baykusheva DR, et al. Femtosecond photoelectron circular dichroism of chemical reactions. <i>Science Advances</i>. 2022;8(28). doi:<a href=\"https://doi.org/10.1126/sciadv.abq2811\">10.1126/sciadv.abq2811</a>","ieee":"V. Svoboda <i>et al.</i>, “Femtosecond photoelectron circular dichroism of chemical reactions,” <i>Science Advances</i>, vol. 8, no. 28. American Association for the Advancement of Science, 2022.","apa":"Svoboda, V., Ram, N. B., Baykusheva, D. R., Zindel, D., Waters, M. D. J., Spenger, B., … Wörner, H. J. (2022). Femtosecond photoelectron circular dichroism of chemical reactions. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.abq2811\">https://doi.org/10.1126/sciadv.abq2811</a>"},"volume":8,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1126/sciadv.abq2811"}],"publisher":"American Association for the Advancement of Science"},{"citation":{"ieee":"H. Utzat and M. Ibáñez, “Molecular engineering enables bright blue LEDs,” <i>Nature</i>, vol. 612, no. 7941. Springer Nature, pp. 638–639, 2022.","ama":"Utzat H, Ibáñez M. Molecular engineering enables bright blue LEDs. <i>Nature</i>. 2022;612(7941):638-639. doi:<a href=\"https://doi.org/10.1038/d41586-022-04447-0\">10.1038/d41586-022-04447-0</a>","apa":"Utzat, H., &#38; Ibáñez, M. (2022). Molecular engineering enables bright blue LEDs. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/d41586-022-04447-0\">https://doi.org/10.1038/d41586-022-04447-0</a>","ista":"Utzat H, Ibáñez M. 2022. Molecular engineering enables bright blue LEDs. Nature. 612(7941), 638–639.","chicago":"Utzat, Hendrik, and Maria Ibáñez. “Molecular Engineering Enables Bright Blue LEDs.” <i>Nature</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/d41586-022-04447-0\">https://doi.org/10.1038/d41586-022-04447-0</a>.","mla":"Utzat, Hendrik, and Maria Ibáñez. “Molecular Engineering Enables Bright Blue LEDs.” <i>Nature</i>, vol. 612, no. 7941, Springer Nature, 2022, pp. 638–39, doi:<a href=\"https://doi.org/10.1038/d41586-022-04447-0\">10.1038/d41586-022-04447-0</a>.","short":"H. Utzat, M. Ibáñez, Nature 612 (2022) 638–639."},"abstract":[{"lang":"eng","text":"Future LEDs could be based on lead halide perovskites. A breakthrough in preparing device-compatible solids composed of nanoscale perovskite crystals overcomes a long-standing hurdle in making blue perovskite LEDs."}],"pmid":1,"type":"journal_article","quality_controlled":"1","publisher":"Springer Nature","corr_author":"1","volume":612,"department":[{"_id":"MaIb"}],"external_id":{"isi":["000934065100010"],"pmid":["36543947"]},"publication_status":"published","date_created":"2023-10-17T11:14:43Z","month":"12","scopus_import":"1","issue":"7941","_id":"14437","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"article_type":"letter_note","year":"2022","day":"21","doi":"10.1038/d41586-022-04447-0","date_published":"2022-12-21T00:00:00Z","intvolume":"       612","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"publication":"Nature","keyword":["Multidisciplinary"],"oa_version":"None","status":"public","language":[{"iso":"eng"}],"article_processing_charge":"No","title":"Molecular engineering enables bright blue LEDs","author":[{"first_name":"Hendrik","last_name":"Utzat","full_name":"Utzat, Hendrik"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","first_name":"Maria"}],"date_updated":"2025-09-10T09:55:51Z","page":"638-639"},{"department":[{"_id":"EdHa"}],"volume":607,"main_file_link":[{"open_access":"1","url":"https://helda.helsinki.fi/items/94433455-4854-45c0-9de8-7326caea8780"}],"corr_author":"1","publisher":"Springer Nature","quality_controlled":"1","type":"journal_article","pmid":1,"abstract":[{"text":"The morphology and functionality of the epithelial lining differ along the intestinal tract, but tissue renewal at all sites is driven by stem cells at the base of crypts1,2,3. Whether stem cell numbers and behaviour vary at different sites is unknown. Here we show using intravital microscopy that, despite similarities in the number and distribution of proliferative cells with an Lgr5 signature in mice, small intestinal crypts contain twice as many effective stem cells as large intestinal crypts. We find that, although passively displaced by a conveyor-belt-like upward movement, small intestinal cells positioned away from the crypt base can function as long-term effective stem cells owing to Wnt-dependent retrograde cellular movement. By contrast, the near absence of retrograde movement in the large intestine restricts cell repositioning, leading to a reduction in effective stem cell number. Moreover, after suppression of the retrograde movement in the small intestine, the number of effective stem cells is reduced, and the rate of monoclonal conversion of crypts is accelerated. Together, these results show that the number of effective stem cells is determined by active retrograde movement, revealing a new channel of stem cell regulation that can be experimentally and pharmacologically manipulated.","lang":"eng"}],"citation":{"short":"M. Azkanaz, B. Corominas-Murtra, S.I.J. Ellenbroek, L. Bruens, A.T. Webb, D. Laskaris, K.C. Oost, S.J.A. Lafirenze, K. Annusver, H.A. Messal, S. Iqbal, D.J. Flanagan, D.J. Huels, F. Rojas-Rodríguez, M. Vizoso, M. Kasper, O.J. Sansom, H.J. Snippert, P. Liberali, B.D. Simons, P. Katajisto, E.B. Hannezo, J. van Rheenen, Nature 607 (2022) 548–554.","mla":"Azkanaz, Maria, et al. “Retrograde Movements Determine Effective Stem Cell Numbers in the Intestine.” <i>Nature</i>, vol. 607, no. 7919, Springer Nature, 2022, pp. 548–54, doi:<a href=\"https://doi.org/10.1038/s41586-022-04962-0\">10.1038/s41586-022-04962-0</a>.","chicago":"Azkanaz, Maria, Bernat Corominas-Murtra, Saskia I. J. Ellenbroek, Lotte Bruens, Anna T. Webb, Dimitrios Laskaris, Koen C. Oost, et al. “Retrograde Movements Determine Effective Stem Cell Numbers in the Intestine.” <i>Nature</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41586-022-04962-0\">https://doi.org/10.1038/s41586-022-04962-0</a>.","ista":"Azkanaz M, Corominas-Murtra B, Ellenbroek SIJ, Bruens L, Webb AT, Laskaris D, Oost KC, Lafirenze SJA, Annusver K, Messal HA, Iqbal S, Flanagan DJ, Huels DJ, Rojas-Rodríguez F, Vizoso M, Kasper M, Sansom OJ, Snippert HJ, Liberali P, Simons BD, Katajisto P, Hannezo EB, van Rheenen J. 2022. Retrograde movements determine effective stem cell numbers in the intestine. Nature. 607(7919), 548–554.","ama":"Azkanaz M, Corominas-Murtra B, Ellenbroek SIJ, et al. Retrograde movements determine effective stem cell numbers in the intestine. <i>Nature</i>. 2022;607(7919):548-554. doi:<a href=\"https://doi.org/10.1038/s41586-022-04962-0\">10.1038/s41586-022-04962-0</a>","apa":"Azkanaz, M., Corominas-Murtra, B., Ellenbroek, S. I. J., Bruens, L., Webb, A. T., Laskaris, D., … van Rheenen, J. (2022). Retrograde movements determine effective stem cell numbers in the intestine. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-022-04962-0\">https://doi.org/10.1038/s41586-022-04962-0</a>","ieee":"M. Azkanaz <i>et al.</i>, “Retrograde movements determine effective stem cell numbers in the intestine,” <i>Nature</i>, vol. 607, no. 7919. Springer Nature, pp. 548–554, 2022."},"_id":"12274","issue":"7919","scopus_import":"1","month":"07","date_created":"2023-01-16T10:01:29Z","publication_status":"published","external_id":{"isi":["000824430000004"],"pmid":["35831497"]},"publication":"Nature","isi":1,"project":[{"name":"Design Principles of Branching Morphogenesis","_id":"05943252-7A3F-11EA-A408-12923DDC885E","grant_number":"851288","call_identifier":"H2020"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       607","date_published":"2022-07-13T00:00:00Z","day":"13","doi":"10.1038/s41586-022-04962-0","oa":1,"ec_funded":1,"acknowledgement":"We thank the members of the van Rheenen laboratory for reading the manuscript, and the members of the bioimaging, FACS and animal facility of the NKI for experimental support. We acknowledge the staff at the MedH Flow Cytometry core facility, Karolinska Institutet, and LCI facility/Nikon Center of Excellence, Karolinska Institutet. This work was financially supported by the Netherlands Organization of Scientific Research NWO (Veni grant 863.15.011 to S.I.J.E. and Vici grant 09150182110004 to J.v.R.) and the CancerGenomics.nl (Netherlands Organisation for Scientific Research) program (to J.v.R.) the Doctor Josef Steiner Foundation (to J.v.R). B.D.S. acknowledges funding from the Royal Society E.P. Abraham Research Professorship (RP\\R1\\180165) and the Wellcome Trust (098357/Z/12/Z and 219478/Z/19/Z). B.C.-M. acknowledges the support of the field of excellence ‘Complexity of life in basic research and innovation’ of the University of Graz. O.J.S. and their laboratory acknowledge CRUK core funding to the CRUK Beatson Institute (A17196 and A31287) and CRUK core funding to the Sansom laboratory (A21139). P.K. and their laboratory are supported by grants from the Swedish Research Council (2018-03078), Cancerfonden (190634), Academy of Finland Centre of Excellence (266869, 304591 and 320185) and the Jane and Aatos Erkko Foundation. P.L. has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 758617). E.H. acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 851288).","article_type":"original","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"year":"2022","page":"548-554","related_material":{"link":[{"relation":"software","url":"https://github.com/JaccovanRheenenLab/Retrograde_movement_Azkanaz_Nature_2022"}]},"date_updated":"2025-04-14T07:52:27Z","title":"Retrograde movements determine effective stem cell numbers in the intestine","author":[{"first_name":"Maria","last_name":"Azkanaz","full_name":"Azkanaz, Maria"},{"first_name":"Bernat","orcid":"0000-0001-9806-5643","full_name":"Corominas-Murtra, Bernat","last_name":"Corominas-Murtra","id":"43BE2298-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Saskia I. J.","full_name":"Ellenbroek, Saskia I. J.","last_name":"Ellenbroek"},{"last_name":"Bruens","full_name":"Bruens, Lotte","first_name":"Lotte"},{"last_name":"Webb","full_name":"Webb, Anna T.","first_name":"Anna T."},{"first_name":"Dimitrios","last_name":"Laskaris","full_name":"Laskaris, Dimitrios"},{"first_name":"Koen C.","last_name":"Oost","full_name":"Oost, Koen C."},{"last_name":"Lafirenze","full_name":"Lafirenze, Simona J. A.","first_name":"Simona J. A."},{"first_name":"Karl","last_name":"Annusver","full_name":"Annusver, Karl"},{"first_name":"Hendrik A.","full_name":"Messal, Hendrik A.","last_name":"Messal"},{"first_name":"Sharif","last_name":"Iqbal","full_name":"Iqbal, Sharif"},{"first_name":"Dustin J.","last_name":"Flanagan","full_name":"Flanagan, Dustin J."},{"first_name":"David J.","full_name":"Huels, David J.","last_name":"Huels"},{"last_name":"Rojas-Rodríguez","full_name":"Rojas-Rodríguez, Felipe","first_name":"Felipe"},{"first_name":"Miguel","full_name":"Vizoso, Miguel","last_name":"Vizoso"},{"last_name":"Kasper","full_name":"Kasper, Maria","first_name":"Maria"},{"full_name":"Sansom, Owen J.","last_name":"Sansom","first_name":"Owen J."},{"full_name":"Snippert, Hugo J.","last_name":"Snippert","first_name":"Hugo J."},{"full_name":"Liberali, Prisca","last_name":"Liberali","first_name":"Prisca"},{"first_name":"Benjamin D.","full_name":"Simons, Benjamin D.","last_name":"Simons"},{"last_name":"Katajisto","full_name":"Katajisto, Pekka","first_name":"Pekka"},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561","first_name":"Edouard B"},{"first_name":"Jacco","full_name":"van Rheenen, Jacco","last_name":"van Rheenen"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","oa_version":"Submitted Version","keyword":["Multidisciplinary"]},{"keyword":["Multidisciplinary"],"oa_version":"None","language":[{"iso":"eng"}],"status":"public","article_processing_charge":"No","title":"Warming-induced monsoon precipitation phase change intensifies glacier mass loss in the southeastern Tibetan Plateau","author":[{"full_name":"Jouberton, Achille","last_name":"Jouberton","first_name":"Achille"},{"last_name":"Shaw","full_name":"Shaw, Thomas E.","first_name":"Thomas E."},{"full_name":"Miles, Evan","last_name":"Miles","first_name":"Evan"},{"last_name":"McCarthy","full_name":"McCarthy, Michael","first_name":"Michael"},{"full_name":"Fugger, Stefan","last_name":"Fugger","first_name":"Stefan"},{"first_name":"Shaoting","last_name":"Ren","full_name":"Ren, Shaoting"},{"first_name":"Amaury","last_name":"Dehecq","full_name":"Dehecq, Amaury"},{"last_name":"Yang","full_name":"Yang, Wei","first_name":"Wei"},{"first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti"}],"date_updated":"2023-02-28T13:50:37Z","article_number":"e2109796119","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"article_type":"original","year":"2022","doi":"10.1073/pnas.2109796119","day":"06","intvolume":"       119","date_published":"2022-09-06T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"PNAS","publication_status":"published","date_created":"2023-02-20T08:10:02Z","month":"09","scopus_import":"1","issue":"37","_id":"12577","abstract":[{"text":"Glaciers are key components of the mountain water towers of Asia and are vital for downstream domestic, agricultural, and industrial uses. The glacier mass loss rate over the southeastern Tibetan Plateau is among the highest in Asia and has accelerated in recent decades. This acceleration has been attributed to increased warming, but the mechanisms behind these glaciers’ high sensitivity to warming remain unclear, while the influence of changes in precipitation over the past decades is poorly quantified. Here, we reconstruct glacier mass changes and catchment runoff since 1975 at a benchmark glacier, Parlung No. 4, to shed light on the drivers of recent mass losses for the monsoonal, spring-accumulation glaciers of the Tibetan Plateau. Our modeling demonstrates how a temperature increase (mean of 0.39<jats:sup>∘</jats:sup>C ⋅dec<jats:sup>−1</jats:sup>since 1990) has accelerated mass loss rates by altering both the ablation and accumulation regimes in a complex manner. The majority of the post-2000 mass loss occurred during the monsoon months, caused by simultaneous decreases in the solid precipitation ratio (from 0.70 to 0.56) and precipitation amount (–10%), leading to reduced monsoon accumulation (–26%). Higher solid precipitation in spring (+18%) during the last two decades was increasingly important in mitigating glacier mass loss by providing mass to the glacier and protecting it from melting in the early monsoon. With bare ice exposed to warmer temperatures for longer periods, icemelt and catchment discharge have unsustainably intensified since the start of the 21st century, raising concerns for long-term water supply and hazard occurrence in the region.","lang":"eng"}],"type":"journal_article","extern":"1","citation":{"short":"A. Jouberton, T.E. Shaw, E. Miles, M. McCarthy, S. Fugger, S. Ren, A. Dehecq, W. Yang, F. Pellicciotti, PNAS 119 (2022).","ama":"Jouberton A, Shaw TE, Miles E, et al. Warming-induced monsoon precipitation phase change intensifies glacier mass loss in the southeastern Tibetan Plateau. <i>PNAS</i>. 2022;119(37). doi:<a href=\"https://doi.org/10.1073/pnas.2109796119\">10.1073/pnas.2109796119</a>","ieee":"A. Jouberton <i>et al.</i>, “Warming-induced monsoon precipitation phase change intensifies glacier mass loss in the southeastern Tibetan Plateau,” <i>PNAS</i>, vol. 119, no. 37. Proceedings of the National Academy of Sciences, 2022.","apa":"Jouberton, A., Shaw, T. E., Miles, E., McCarthy, M., Fugger, S., Ren, S., … Pellicciotti, F. (2022). Warming-induced monsoon precipitation phase change intensifies glacier mass loss in the southeastern Tibetan Plateau. <i>PNAS</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2109796119\">https://doi.org/10.1073/pnas.2109796119</a>","chicago":"Jouberton, Achille, Thomas E. Shaw, Evan Miles, Michael McCarthy, Stefan Fugger, Shaoting Ren, Amaury Dehecq, Wei Yang, and Francesca Pellicciotti. “Warming-Induced Monsoon Precipitation Phase Change Intensifies Glacier Mass Loss in the Southeastern Tibetan Plateau.” <i>PNAS</i>. Proceedings of the National Academy of Sciences, 2022. <a href=\"https://doi.org/10.1073/pnas.2109796119\">https://doi.org/10.1073/pnas.2109796119</a>.","ista":"Jouberton A, Shaw TE, Miles E, McCarthy M, Fugger S, Ren S, Dehecq A, Yang W, Pellicciotti F. 2022. Warming-induced monsoon precipitation phase change intensifies glacier mass loss in the southeastern Tibetan Plateau. PNAS. 119(37), e2109796119.","mla":"Jouberton, Achille, et al. “Warming-Induced Monsoon Precipitation Phase Change Intensifies Glacier Mass Loss in the Southeastern Tibetan Plateau.” <i>PNAS</i>, vol. 119, no. 37, e2109796119, Proceedings of the National Academy of Sciences, 2022, doi:<a href=\"https://doi.org/10.1073/pnas.2109796119\">10.1073/pnas.2109796119</a>."},"quality_controlled":"1","publisher":"Proceedings of the National Academy of Sciences","volume":119},{"doi":"10.1038/s41467-022-30673-1","day":"27","oa":1,"intvolume":"        13","date_published":"2022-05-27T00:00:00Z","article_number":"2987","publication_identifier":{"issn":["2041-1723"]},"year":"2022","article_type":"original","publication":"Nature Communications","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"title":"Structural basis for broad anti-phage immunity by DISARM","author":[{"first_name":"Jack Peter Kelly","full_name":"Bravo, Jack Peter Kelly","last_name":"Bravo","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","orcid":"0000-0003-0456-0753"},{"first_name":"Cristian","full_name":"Aparicio-Maldonado, Cristian","last_name":"Aparicio-Maldonado"},{"last_name":"Nobrega","full_name":"Nobrega, Franklin L.","first_name":"Franklin L."},{"first_name":"Stan J. J.","full_name":"Brouns, Stan J. J.","last_name":"Brouns"},{"full_name":"Taylor, David W.","last_name":"Taylor","first_name":"David W."}],"date_updated":"2024-06-04T06:16:38Z","status":"public","language":[{"iso":"eng"}],"article_processing_charge":"Yes","type":"journal_article","abstract":[{"text":"In the evolutionary arms race against phage, bacteria have assembled a diverse arsenal of antiviral immune strategies. While the recently discovered DISARM (Defense Island System Associated with Restriction-Modification) systems can provide protection against a wide range of phage, the molecular mechanisms that underpin broad antiviral targeting but avoiding autoimmunity remain enigmatic. Here, we report cryo-EM structures of the core DISARM complex, DrmAB, both alone and in complex with an unmethylated phage DNA mimetic. These structures reveal that DrmAB core complex is autoinhibited by a trigger loop (TL) within DrmA and binding to DNA substrates containing a 5′ overhang dislodges the TL, initiating a long-range structural rearrangement for DrmAB activation. Together with structure-guided in vivo studies, our work provides insights into the mechanism of phage DNA recognition and specific activation of this widespread antiviral defense system.","lang":"eng"}],"pmid":1,"extern":"1","citation":{"short":"J.P.K. Bravo, C. Aparicio-Maldonado, F.L. Nobrega, S.J.J. Brouns, D.W. Taylor, Nature Communications 13 (2022).","ieee":"J. P. K. Bravo, C. Aparicio-Maldonado, F. L. Nobrega, S. J. J. Brouns, and D. W. Taylor, “Structural basis for broad anti-phage immunity by DISARM,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","apa":"Bravo, J. P. K., Aparicio-Maldonado, C., Nobrega, F. L., Brouns, S. J. J., &#38; Taylor, D. W. (2022). Structural basis for broad anti-phage immunity by DISARM. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-30673-1\">https://doi.org/10.1038/s41467-022-30673-1</a>","ama":"Bravo JPK, Aparicio-Maldonado C, Nobrega FL, Brouns SJJ, Taylor DW. Structural basis for broad anti-phage immunity by DISARM. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-30673-1\">10.1038/s41467-022-30673-1</a>","mla":"Bravo, Jack Peter Kelly, et al. “Structural Basis for Broad Anti-Phage Immunity by DISARM.” <i>Nature Communications</i>, vol. 13, 2987, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-30673-1\">10.1038/s41467-022-30673-1</a>.","ista":"Bravo JPK, Aparicio-Maldonado C, Nobrega FL, Brouns SJJ, Taylor DW. 2022. Structural basis for broad anti-phage immunity by DISARM. Nature Communications. 13, 2987.","chicago":"Bravo, Jack Peter Kelly, Cristian Aparicio-Maldonado, Franklin L. Nobrega, Stan J. J. Brouns, and David W. Taylor. “Structural Basis for Broad Anti-Phage Immunity by DISARM.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-30673-1\">https://doi.org/10.1038/s41467-022-30673-1</a>."},"quality_controlled":"1","volume":13,"publisher":"Springer Nature","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-022-30673-1"}],"publication_status":"published","date_created":"2024-03-20T10:41:59Z","external_id":{"pmid":["35624106"]},"_id":"15133","month":"05","scopus_import":"1"},{"external_id":{"pmid":["35595728"]},"date_created":"2024-03-20T10:42:05Z","publication_status":"published","scopus_import":"1","month":"05","_id":"15134","quality_controlled":"1","extern":"1","type":"journal_article","pmid":1,"abstract":[{"text":"CRISPR-Cas systems are adaptive immune systems that protect prokaryotes from foreign nucleic acids, such as bacteriophages. Two of the most prevalent CRISPR-Cas systems include type I and type III. Interestingly, the type I-D interference proteins contain characteristic features of both type I and type III systems. Here, we present the structures of type I-D Cascade bound to both a double-stranded (ds)DNA and a single-stranded (ss)RNA target at 2.9 and 3.1 Å, respectively. We show that type I-D Cascade is capable of specifically binding ssRNA and reveal how PAM recognition of dsDNA targets initiates long-range structural rearrangements that likely primes Cas10d for Cas3′ binding and subsequent non-target strand DNA cleavage. These structures allow us to model how binding of the anti-CRISPR protein AcrID1 likely blocks target dsDNA binding via competitive inhibition of the DNA substrate engagement with the Cas10d active site. This work elucidates the unique mechanisms used by type I-D Cascade for discrimination of single-stranded and double stranded targets. Thus, our data supports a model for the hybrid nature of this complex with features of type III and type I systems.","lang":"eng"}],"citation":{"short":"E.A. Schwartz, T.M. McBride, J.P.K. Bravo, D. Wrapp, P.C. Fineran, R.D. Fagerlund, D.W. Taylor, Nature Communications 13 (2022).","chicago":"Schwartz, Evan A., Tess M. McBride, Jack Peter Kelly Bravo, Daniel Wrapp, Peter C. Fineran, Robert D. Fagerlund, and David W. Taylor. “Structural Rearrangements Allow Nucleic Acid Discrimination by Type I-D Cascade.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-30402-8\">https://doi.org/10.1038/s41467-022-30402-8</a>.","ista":"Schwartz EA, McBride TM, Bravo JPK, Wrapp D, Fineran PC, Fagerlund RD, Taylor DW. 2022. Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. Nature Communications. 13, 2829.","mla":"Schwartz, Evan A., et al. “Structural Rearrangements Allow Nucleic Acid Discrimination by Type I-D Cascade.” <i>Nature Communications</i>, vol. 13, 2829, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-30402-8\">10.1038/s41467-022-30402-8</a>.","ama":"Schwartz EA, McBride TM, Bravo JPK, et al. Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-30402-8\">10.1038/s41467-022-30402-8</a>","apa":"Schwartz, E. A., McBride, T. M., Bravo, J. P. K., Wrapp, D., Fineran, P. C., Fagerlund, R. D., &#38; Taylor, D. W. (2022). Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-30402-8\">https://doi.org/10.1038/s41467-022-30402-8</a>","ieee":"E. A. Schwartz <i>et al.</i>, “Structural rearrangements allow nucleic acid discrimination by type I-D Cascade,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022."},"main_file_link":[{"url":"https://doi.org/10.1038/s41467-022-30402-8","open_access":"1"}],"publisher":"Springer Nature","volume":13,"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"oa_version":"Published Version","article_processing_charge":"Yes","status":"public","language":[{"iso":"eng"}],"date_updated":"2024-06-04T06:14:28Z","author":[{"first_name":"Evan A.","last_name":"Schwartz","full_name":"Schwartz, Evan A."},{"last_name":"McBride","full_name":"McBride, Tess M.","first_name":"Tess M."},{"orcid":"0000-0003-0456-0753","full_name":"Bravo, Jack Peter Kelly","last_name":"Bravo","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","first_name":"Jack Peter Kelly"},{"first_name":"Daniel","last_name":"Wrapp","full_name":"Wrapp, Daniel"},{"first_name":"Peter C.","last_name":"Fineran","full_name":"Fineran, Peter C."},{"full_name":"Fagerlund, Robert D.","last_name":"Fagerlund","first_name":"Robert D."},{"first_name":"David W.","last_name":"Taylor","full_name":"Taylor, David W."}],"title":"Structural rearrangements allow nucleic acid discrimination by type I-D Cascade","article_type":"original","publication_identifier":{"issn":["2041-1723"]},"year":"2022","article_number":"2829","intvolume":"        13","date_published":"2022-05-20T00:00:00Z","day":"20","doi":"10.1038/s41467-022-30402-8","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Nature Communications"},{"keyword":["Multidisciplinary"],"oa_version":"Preprint","article_processing_charge":"No","status":"public","language":[{"iso":"eng"}],"page":"646-650","date_updated":"2024-04-02T07:17:25Z","author":[{"full_name":"Taverna, Roberto","last_name":"Taverna","first_name":"Roberto"},{"first_name":"Roberto","last_name":"Turolla","full_name":"Turolla, Roberto"},{"first_name":"Fabio","full_name":"Muleri, Fabio","last_name":"Muleri"},{"full_name":"Heyl, Jeremy","last_name":"Heyl","first_name":"Jeremy"},{"last_name":"Zane","full_name":"Zane, Silvia","first_name":"Silvia"},{"first_name":"Luca","full_name":"Baldini, Luca","last_name":"Baldini"},{"full_name":"González-Caniulef, Denis","last_name":"González-Caniulef","first_name":"Denis"},{"first_name":"Matteo","last_name":"Bachetti","full_name":"Bachetti, Matteo"},{"first_name":"John","last_name":"Rankin","full_name":"Rankin, John"},{"first_name":"Ilaria","orcid":"0000-0002-4770-5388","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","full_name":"Caiazzo, Ilaria","last_name":"Caiazzo"},{"first_name":"Niccolò","full_name":"Di Lalla, Niccolò","last_name":"Di Lalla"},{"full_name":"Doroshenko, Victor","last_name":"Doroshenko","first_name":"Victor"},{"last_name":"Errando","full_name":"Errando, Manel","first_name":"Manel"},{"last_name":"Gau","full_name":"Gau, Ephraim","first_name":"Ephraim"},{"first_name":"Demet","full_name":"Kırmızıbayrak, Demet","last_name":"Kırmızıbayrak"},{"first_name":"Henric","full_name":"Krawczynski, Henric","last_name":"Krawczynski"},{"first_name":"Michela","full_name":"Negro, Michela","last_name":"Negro"},{"first_name":"Mason","last_name":"Ng","full_name":"Ng, Mason"},{"first_name":"Nicola","last_name":"Omodei","full_name":"Omodei, Nicola"},{"last_name":"Possenti","full_name":"Possenti, Andrea","first_name":"Andrea"},{"first_name":"Toru","last_name":"Tamagawa","full_name":"Tamagawa, Toru"},{"full_name":"Uchiyama, Keisuke","last_name":"Uchiyama","first_name":"Keisuke"},{"first_name":"Martin C.","full_name":"Weisskopf, Martin C.","last_name":"Weisskopf"},{"first_name":"Ivan","full_name":"Agudo, Ivan","last_name":"Agudo"},{"first_name":"Lucio A.","full_name":"Antonelli, Lucio A.","last_name":"Antonelli"},{"full_name":"Baumgartner, Wayne H.","last_name":"Baumgartner","first_name":"Wayne H."},{"full_name":"Bellazzini, Ronaldo","last_name":"Bellazzini","first_name":"Ronaldo"},{"first_name":"Stefano","last_name":"Bianchi","full_name":"Bianchi, Stefano"},{"first_name":"Stephen D.","last_name":"Bongiorno","full_name":"Bongiorno, Stephen D."},{"first_name":"Raffaella","full_name":"Bonino, Raffaella","last_name":"Bonino"},{"last_name":"Brez","full_name":"Brez, Alessandro","first_name":"Alessandro"},{"first_name":"Niccolò","full_name":"Bucciantini, Niccolò","last_name":"Bucciantini"},{"first_name":"Fiamma","last_name":"Capitanio","full_name":"Capitanio, Fiamma"},{"last_name":"Castellano","full_name":"Castellano, Simone","first_name":"Simone"},{"first_name":"Elisabetta","last_name":"Cavazzuti","full_name":"Cavazzuti, Elisabetta"},{"last_name":"Ciprini","full_name":"Ciprini, Stefano","first_name":"Stefano"},{"last_name":"Costa","full_name":"Costa, Enrico","first_name":"Enrico"},{"full_name":"De Rosa, Alessandra","last_name":"De Rosa","first_name":"Alessandra"},{"last_name":"Del Monte","full_name":"Del Monte, Ettore","first_name":"Ettore"},{"full_name":"Di Gesu, Laura","last_name":"Di Gesu","first_name":"Laura"},{"last_name":"Di Marco","full_name":"Di Marco, Alessandro","first_name":"Alessandro"},{"first_name":"Immacolata","last_name":"Donnarumma","full_name":"Donnarumma, Immacolata"},{"full_name":"Dovčiak, Michal","last_name":"Dovčiak","first_name":"Michal"},{"first_name":"Steven R.","last_name":"Ehlert","full_name":"Ehlert, Steven R."},{"last_name":"Enoto","full_name":"Enoto, Teruaki","first_name":"Teruaki"},{"full_name":"Evangelista, Yuri","last_name":"Evangelista","first_name":"Yuri"},{"last_name":"Fabiani","full_name":"Fabiani, Sergio","first_name":"Sergio"},{"first_name":"Riccardo","last_name":"Ferrazzoli","full_name":"Ferrazzoli, Riccardo"},{"first_name":"Javier A.","last_name":"Garcia","full_name":"Garcia, Javier A."},{"first_name":"Shuichi","full_name":"Gunji, Shuichi","last_name":"Gunji"},{"last_name":"Hayashida","full_name":"Hayashida, Kiyoshi","first_name":"Kiyoshi"},{"last_name":"Iwakiri","full_name":"Iwakiri, Wataru","first_name":"Wataru"},{"first_name":"Svetlana G.","last_name":"Jorstad","full_name":"Jorstad, Svetlana G."},{"first_name":"Vladimir","last_name":"Karas","full_name":"Karas, Vladimir"},{"last_name":"Kitaguchi","full_name":"Kitaguchi, Takao","first_name":"Takao"},{"first_name":"Jeffery J.","last_name":"Kolodziejczak","full_name":"Kolodziejczak, Jeffery J."},{"first_name":"Fabio","last_name":"La Monaca","full_name":"La Monaca, Fabio"},{"full_name":"Latronico, Luca","last_name":"Latronico","first_name":"Luca"},{"first_name":"Ioannis","last_name":"Liodakis","full_name":"Liodakis, Ioannis"},{"first_name":"Simone","last_name":"Maldera","full_name":"Maldera, Simone"},{"first_name":"Alberto","full_name":"Manfreda, Alberto","last_name":"Manfreda"},{"full_name":"Marin, Frédéric","last_name":"Marin","first_name":"Frédéric"},{"last_name":"Marinucci","full_name":"Marinucci, Andrea","first_name":"Andrea"},{"first_name":"Alan P.","last_name":"Marscher","full_name":"Marscher, Alan P."},{"full_name":"Marshall, Herman L.","last_name":"Marshall","first_name":"Herman L."},{"full_name":"Matt, Giorgio","last_name":"Matt","first_name":"Giorgio"},{"last_name":"Mitsuishi","full_name":"Mitsuishi, Ikuyuki","first_name":"Ikuyuki"},{"first_name":"Tsunefumi","last_name":"Mizuno","full_name":"Mizuno, Tsunefumi"},{"full_name":"Ng, Stephen C.-Y.","last_name":"Ng","first_name":"Stephen C.-Y."},{"last_name":"O’Dell","full_name":"O’Dell, Stephen L.","first_name":"Stephen L."},{"last_name":"Oppedisano","full_name":"Oppedisano, Chiara","first_name":"Chiara"},{"last_name":"Papitto","full_name":"Papitto, Alessandro","first_name":"Alessandro"},{"full_name":"Pavlov, George G.","last_name":"Pavlov","first_name":"George G."},{"first_name":"Abel L.","full_name":"Peirson, Abel L.","last_name":"Peirson"},{"first_name":"Matteo","last_name":"Perri","full_name":"Perri, Matteo"},{"last_name":"Pesce-Rollins","full_name":"Pesce-Rollins, Melissa","first_name":"Melissa"},{"first_name":"Maura","last_name":"Pilia","full_name":"Pilia, Maura"},{"full_name":"Poutanen, Juri","last_name":"Poutanen","first_name":"Juri"},{"last_name":"Puccetti","full_name":"Puccetti, Simonetta","first_name":"Simonetta"},{"last_name":"Ramsey","full_name":"Ramsey, Brian D.","first_name":"Brian D."},{"last_name":"Ratheesh","full_name":"Ratheesh, Ajay","first_name":"Ajay"},{"first_name":"Roger W.","last_name":"Romani","full_name":"Romani, Roger W."},{"first_name":"Carmelo","full_name":"Sgrò, Carmelo","last_name":"Sgrò"},{"first_name":"Patrick","last_name":"Slane","full_name":"Slane, Patrick"},{"full_name":"Soffitta, Paolo","last_name":"Soffitta","first_name":"Paolo"},{"full_name":"Spandre, Gloria","last_name":"Spandre","first_name":"Gloria"},{"first_name":"Fabrizio","last_name":"Tavecchio","full_name":"Tavecchio, Fabrizio"},{"first_name":"Yuzuru","full_name":"Tawara, Yuzuru","last_name":"Tawara"},{"first_name":"Allyn F.","full_name":"Tennant, Allyn F.","last_name":"Tennant"},{"full_name":"Thomas, Nicholas E.","last_name":"Thomas","first_name":"Nicholas E."},{"full_name":"Tombesi, Francesco","last_name":"Tombesi","first_name":"Francesco"},{"first_name":"Alessio","full_name":"Trois, Alessio","last_name":"Trois"},{"first_name":"Sergey S.","last_name":"Tsygankov","full_name":"Tsygankov, Sergey S."},{"full_name":"Vink, Jacco","last_name":"Vink","first_name":"Jacco"},{"last_name":"Wu","full_name":"Wu, Kinwah","first_name":"Kinwah"},{"first_name":"Fei","last_name":"Xie","full_name":"Xie, Fei"}],"title":"Polarized x-rays from a magnetar","publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"article_type":"original","year":"2022","date_published":"2022-11-03T00:00:00Z","intvolume":"       378","oa":1,"doi":"10.1126/science.add0080","day":"03","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Science","arxiv":1,"external_id":{"arxiv":["2205.08898"]},"date_created":"2024-03-26T09:51:30Z","publication_status":"published","issue":"6620","scopus_import":"1","month":"11","_id":"15205","quality_controlled":"1","citation":{"ieee":"R. Taverna <i>et al.</i>, “Polarized x-rays from a magnetar,” <i>Science</i>, vol. 378, no. 6620. American Association for the Advancement of Science, pp. 646–650, 2022.","ama":"Taverna R, Turolla R, Muleri F, et al. Polarized x-rays from a magnetar. <i>Science</i>. 2022;378(6620):646-650. doi:<a href=\"https://doi.org/10.1126/science.add0080\">10.1126/science.add0080</a>","apa":"Taverna, R., Turolla, R., Muleri, F., Heyl, J., Zane, S., Baldini, L., … Xie, F. (2022). Polarized x-rays from a magnetar. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.add0080\">https://doi.org/10.1126/science.add0080</a>","chicago":"Taverna, Roberto, Roberto Turolla, Fabio Muleri, Jeremy Heyl, Silvia Zane, Luca Baldini, Denis González-Caniulef, et al. “Polarized X-Rays from a Magnetar.” <i>Science</i>. American Association for the Advancement of Science, 2022. <a href=\"https://doi.org/10.1126/science.add0080\">https://doi.org/10.1126/science.add0080</a>.","ista":"Taverna R, Turolla R, Muleri F, Heyl J, Zane S, Baldini L, González-Caniulef D, Bachetti M, Rankin J, Caiazzo I, Di Lalla N, Doroshenko V, Errando M, Gau E, Kırmızıbayrak D, Krawczynski H, Negro M, Ng M, Omodei N, Possenti A, Tamagawa T, Uchiyama K, Weisskopf MC, Agudo I, Antonelli LA, Baumgartner WH, Bellazzini R, Bianchi S, Bongiorno SD, Bonino R, Brez A, Bucciantini N, Capitanio F, Castellano S, Cavazzuti E, Ciprini S, Costa E, De Rosa A, Del Monte E, Di Gesu L, Di Marco A, Donnarumma I, Dovčiak M, Ehlert SR, Enoto T, Evangelista Y, Fabiani S, Ferrazzoli R, Garcia JA, Gunji S, Hayashida K, Iwakiri W, Jorstad SG, Karas V, Kitaguchi T, Kolodziejczak JJ, La Monaca F, Latronico L, Liodakis I, Maldera S, Manfreda A, Marin F, Marinucci A, Marscher AP, Marshall HL, Matt G, Mitsuishi I, Mizuno T, Ng SC-Y, O’Dell SL, Oppedisano C, Papitto A, Pavlov GG, Peirson AL, Perri M, Pesce-Rollins M, Pilia M, Poutanen J, Puccetti S, Ramsey BD, Ratheesh A, Romani RW, Sgrò C, Slane P, Soffitta P, Spandre G, Tavecchio F, Tawara Y, Tennant AF, Thomas NE, Tombesi F, Trois A, Tsygankov SS, Vink J, Wu K, Xie F. 2022. Polarized x-rays from a magnetar. Science. 378(6620), 646–650.","mla":"Taverna, Roberto, et al. “Polarized X-Rays from a Magnetar.” <i>Science</i>, vol. 378, no. 6620, American Association for the Advancement of Science, 2022, pp. 646–50, doi:<a href=\"https://doi.org/10.1126/science.add0080\">10.1126/science.add0080</a>.","short":"R. Taverna, R. Turolla, F. Muleri, J. Heyl, S. Zane, L. Baldini, D. González-Caniulef, M. Bachetti, J. Rankin, I. Caiazzo, N. Di Lalla, V. Doroshenko, M. Errando, E. Gau, D. Kırmızıbayrak, H. Krawczynski, M. Negro, M. Ng, N. Omodei, A. Possenti, T. Tamagawa, K. Uchiyama, M.C. Weisskopf, I. Agudo, L.A. Antonelli, W.H. Baumgartner, R. Bellazzini, S. Bianchi, S.D. Bongiorno, R. Bonino, A. Brez, N. Bucciantini, F. Capitanio, S. Castellano, E. Cavazzuti, S. Ciprini, E. Costa, A. De Rosa, E. Del Monte, L. Di Gesu, A. Di Marco, I. Donnarumma, M. Dovčiak, S.R. Ehlert, T. Enoto, Y. Evangelista, S. Fabiani, R. Ferrazzoli, J.A. Garcia, S. Gunji, K. Hayashida, W. Iwakiri, S.G. Jorstad, V. Karas, T. Kitaguchi, J.J. Kolodziejczak, F. La Monaca, L. Latronico, I. Liodakis, S. Maldera, A. Manfreda, F. Marin, A. Marinucci, A.P. Marscher, H.L. Marshall, G. Matt, I. Mitsuishi, T. Mizuno, S.C.-Y. Ng, S.L. O’Dell, C. Oppedisano, A. Papitto, G.G. Pavlov, A.L. Peirson, M. Perri, M. Pesce-Rollins, M. Pilia, J. Poutanen, S. Puccetti, B.D. Ramsey, A. Ratheesh, R.W. Romani, C. Sgrò, P. Slane, P. Soffitta, G. Spandre, F. Tavecchio, Y. Tawara, A.F. Tennant, N.E. Thomas, F. Tombesi, A. Trois, S.S. Tsygankov, J. Vink, K. Wu, F. Xie, Science 378 (2022) 646–650."},"abstract":[{"lang":"eng","text":"Magnetars are neutron stars with ultrastrong magnetic fields, which can be observed in x-rays. Polarization measurements could provide information on their magnetic fields and surface properties. We observed polarized x-rays from the magnetar 4U 0142+61 using the Imaging X-ray Polarimetry Explorer and found a linear polarization degree of 13.5 ± 0.8% averaged over the 2– to 8–kilo–electron volt band. The polarization changes with energy: The degree is 15.0 ± 1.0% at 2 to 4 kilo–electron volts, drops below the instrumental sensitivity ~4 to 5 kilo–electron volts, and rises to 35.2 ± 7.1% at 5.5 to 8 kilo–electron volts. The polarization angle also changes by 90° at ~4 to 5 kilo–electron volts. These results are consistent with a model in which thermal radiation from the magnetar surface is reprocessed by scattering off charged particles in the magnetosphere."}],"type":"journal_article","extern":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2205.08898"}],"publisher":"American Association for the Advancement of Science","volume":378},{"language":[{"iso":"eng"}],"status":"public","article_processing_charge":"No","author":[{"first_name":"Kevin B.","full_name":"Burdge, Kevin B.","last_name":"Burdge"},{"first_name":"Thomas R.","last_name":"Marsh","full_name":"Marsh, Thomas R."},{"first_name":"Jim","full_name":"Fuller, Jim","last_name":"Fuller"},{"last_name":"Bellm","full_name":"Bellm, Eric C.","first_name":"Eric C."},{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","full_name":"Caiazzo, Ilaria","last_name":"Caiazzo","orcid":"0000-0002-4770-5388","first_name":"Ilaria"},{"last_name":"Chakrabarty","full_name":"Chakrabarty, Deepto","first_name":"Deepto"},{"last_name":"Coughlin","full_name":"Coughlin, Michael W.","first_name":"Michael W."},{"last_name":"De","full_name":"De, Kishalay","first_name":"Kishalay"},{"first_name":"V. S.","full_name":"Dhillon, V. S.","last_name":"Dhillon"},{"first_name":"Matthew J.","last_name":"Graham","full_name":"Graham, Matthew J."},{"first_name":"Pablo","full_name":"Rodríguez-Gil, Pablo","last_name":"Rodríguez-Gil"},{"full_name":"Jaodand, Amruta D.","last_name":"Jaodand","first_name":"Amruta D."},{"last_name":"Kaplan","full_name":"Kaplan, David L.","first_name":"David L."},{"first_name":"Erin","full_name":"Kara, Erin","last_name":"Kara"},{"last_name":"Kong","full_name":"Kong, Albert K. H.","first_name":"Albert K. H."},{"first_name":"S. R.","full_name":"Kulkarni, S. R.","last_name":"Kulkarni"},{"last_name":"Li","full_name":"Li, Kwan-Lok","first_name":"Kwan-Lok"},{"first_name":"S. P.","last_name":"Littlefair","full_name":"Littlefair, S. P."},{"last_name":"Majid","full_name":"Majid, Walid A.","first_name":"Walid A."},{"last_name":"Mróz","full_name":"Mróz, Przemek","first_name":"Przemek"},{"first_name":"Aaron B.","last_name":"Pearlman","full_name":"Pearlman, Aaron B."},{"full_name":"Phinney, E. S.","last_name":"Phinney","first_name":"E. S."},{"first_name":"Jan van","last_name":"Roestel","full_name":"Roestel, Jan van"},{"first_name":"Robert A.","last_name":"Simcoe","full_name":"Simcoe, Robert A."},{"first_name":"Igor","last_name":"Andreoni","full_name":"Andreoni, Igor"},{"full_name":"Drake, Andrew J.","last_name":"Drake","first_name":"Andrew J."},{"first_name":"Richard G.","full_name":"Dekany, Richard G.","last_name":"Dekany"},{"first_name":"Dmitry A.","full_name":"Duev, Dmitry A.","last_name":"Duev"},{"first_name":"Erik C.","full_name":"Kool, Erik C.","last_name":"Kool"},{"first_name":"Ashish A.","last_name":"Mahabal","full_name":"Mahabal, Ashish A."},{"full_name":"Medford, Michael S.","last_name":"Medford","first_name":"Michael S."},{"full_name":"Riddle, Reed","last_name":"Riddle","first_name":"Reed"},{"first_name":"Thomas A.","last_name":"Prince","full_name":"Prince, Thomas A."}],"title":"A 62-minute orbital period black widow binary in a wide hierarchical triple","date_updated":"2024-04-02T07:26:19Z","page":"41-45","keyword":["Multidisciplinary"],"oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"publication":"Nature","article_type":"original","year":"2022","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"day":"04","doi":"10.1038/s41586-022-04551-1","oa":1,"intvolume":"       605","date_published":"2022-05-04T00:00:00Z","month":"05","issue":"7908","scopus_import":"1","_id":"15211","external_id":{"pmid":["35508781"],"arxiv":["2205.02278"]},"publication_status":"published","date_created":"2024-03-26T10:29:26Z","publisher":"Springer Nature","main_file_link":[{"url":"https://arxiv.org/abs/2205.02278","open_access":"1"}],"volume":605,"pmid":1,"extern":"1","abstract":[{"lang":"eng","text":"Over a dozen millisecond pulsars are ablating low-mass companions in close binary systems. In the original ‘black widow’, the eight-hour orbital period eclipsing pulsar PSR J1959+2048 (PSR B1957+20)1, high-energy emission originating from the pulsar2 is irradiating and may eventually destroy3 a low-mass companion. These systems are not only physical laboratories that reveal the interesting results of exposing a close companion star to the relativistic energy output of a pulsar, but are also believed to harbour some of the most massive neutron stars4, allowing for robust tests of the neutron star equation of state. Here we report observations of ZTF J1406+1222, a wide hierarchical triple hosting a 62-minute orbital period black widow candidate, the optical flux of which varies by a factor of more than ten. ZTF J1406+1222 pushes the boundaries of evolutionary models5, falling below the 80-minute minimum orbital period of hydrogen-rich systems. The wide tertiary companion is a rare low-metallicity cool subdwarf star, and the system has a Galactic halo orbit consistent with passing near the Galactic Centre, making it a probe of formation channels, neutron star kick physics6 and binary evolution."}],"type":"journal_article","citation":{"ista":"Burdge KB, Marsh TR, Fuller J, Bellm EC, Caiazzo I, Chakrabarty D, Coughlin MW, De K, Dhillon VS, Graham MJ, Rodríguez-Gil P, Jaodand AD, Kaplan DL, Kara E, Kong AKH, Kulkarni SR, Li K-L, Littlefair SP, Majid WA, Mróz P, Pearlman AB, Phinney ES, Roestel J van, Simcoe RA, Andreoni I, Drake AJ, Dekany RG, Duev DA, Kool EC, Mahabal AA, Medford MS, Riddle R, Prince TA. 2022. A 62-minute orbital period black widow binary in a wide hierarchical triple. Nature. 605(7908), 41–45.","chicago":"Burdge, Kevin B., Thomas R. Marsh, Jim Fuller, Eric C. Bellm, Ilaria Caiazzo, Deepto Chakrabarty, Michael W. Coughlin, et al. “A 62-Minute Orbital Period Black Widow Binary in a Wide Hierarchical Triple.” <i>Nature</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41586-022-04551-1\">https://doi.org/10.1038/s41586-022-04551-1</a>.","mla":"Burdge, Kevin B., et al. “A 62-Minute Orbital Period Black Widow Binary in a Wide Hierarchical Triple.” <i>Nature</i>, vol. 605, no. 7908, Springer Nature, 2022, pp. 41–45, doi:<a href=\"https://doi.org/10.1038/s41586-022-04551-1\">10.1038/s41586-022-04551-1</a>.","ieee":"K. B. Burdge <i>et al.</i>, “A 62-minute orbital period black widow binary in a wide hierarchical triple,” <i>Nature</i>, vol. 605, no. 7908. Springer Nature, pp. 41–45, 2022.","ama":"Burdge KB, Marsh TR, Fuller J, et al. A 62-minute orbital period black widow binary in a wide hierarchical triple. <i>Nature</i>. 2022;605(7908):41-45. doi:<a href=\"https://doi.org/10.1038/s41586-022-04551-1\">10.1038/s41586-022-04551-1</a>","apa":"Burdge, K. B., Marsh, T. R., Fuller, J., Bellm, E. C., Caiazzo, I., Chakrabarty, D., … Prince, T. A. (2022). A 62-minute orbital period black widow binary in a wide hierarchical triple. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-022-04551-1\">https://doi.org/10.1038/s41586-022-04551-1</a>","short":"K.B. Burdge, T.R. Marsh, J. Fuller, E.C. Bellm, I. Caiazzo, D. Chakrabarty, M.W. Coughlin, K. De, V.S. Dhillon, M.J. Graham, P. Rodríguez-Gil, A.D. Jaodand, D.L. Kaplan, E. Kara, A.K.H. Kong, S.R. Kulkarni, K.-L. Li, S.P. Littlefair, W.A. Majid, P. Mróz, A.B. Pearlman, E.S. Phinney, J. van Roestel, R.A. Simcoe, I. Andreoni, A.J. Drake, R.G. Dekany, D.A. Duev, E.C. Kool, A.A. Mahabal, M.S. Medford, R. Riddle, T.A. Prince, Nature 605 (2022) 41–45."},"quality_controlled":"1"},{"date_created":"2023-01-12T11:56:45Z","publication_status":"published","external_id":{"arxiv":["2203.07829"],"isi":["000899725400001"],"pmid":["36517713"]},"_id":"12118","scopus_import":"1","issue":"7940","month":"12","quality_controlled":"1","abstract":[{"lang":"eng","text":"Hybrid semiconductor–superconductor devices hold great promise for realizing topological quantum computing with Majorana zero modes1,2,3,4,5. However, multiple claims of Majorana detection, based on either tunnelling6,7,8,9,10 or Coulomb blockade (CB) spectroscopy11,12, remain disputed. Here we devise an experimental protocol that allows us to perform both types of measurement on the same hybrid island by adjusting its charging energy via tunable junctions to the normal leads. This method reduces ambiguities of Majorana detections by checking the consistency between CB spectroscopy and zero-bias peaks in non-blockaded transport. Specifically, we observe junction-dependent, even–odd modulated, single-electron CB peaks in InAs/Al hybrid nanowires without concomitant low-bias peaks in tunnelling spectroscopy. We provide a theoretical interpretation of the experimental observations in terms of low-energy, longitudinally confined island states rather than overlapping Majorana modes. Our results highlight the importance of combined measurements on the same device for the identification of topological Majorana zero modes."}],"pmid":1,"type":"journal_article","citation":{"mla":"Valentini, Marco, et al. “Majorana-like Coulomb Spectroscopy in the Absence of Zero-Bias Peaks.” <i>Nature</i>, vol. 612, no. 7940, Springer Nature, 2022, pp. 442–47, doi:<a href=\"https://doi.org/10.1038/s41586-022-05382-w\">10.1038/s41586-022-05382-w</a>.","chicago":"Valentini, Marco, Maksim Borovkov, Elsa Prada, Sara Martí-Sánchez, Marc Botifoll, Andrea C Hofmann, Jordi Arbiol, Ramón Aguado, Pablo San-Jose, and Georgios Katsaros. “Majorana-like Coulomb Spectroscopy in the Absence of Zero-Bias Peaks.” <i>Nature</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41586-022-05382-w\">https://doi.org/10.1038/s41586-022-05382-w</a>.","ista":"Valentini M, Borovkov M, Prada E, Martí-Sánchez S, Botifoll M, Hofmann AC, Arbiol J, Aguado R, San-Jose P, Katsaros G. 2022. Majorana-like Coulomb spectroscopy in the absence of zero-bias peaks. Nature. 612(7940), 442–447.","apa":"Valentini, M., Borovkov, M., Prada, E., Martí-Sánchez, S., Botifoll, M., Hofmann, A. C., … Katsaros, G. (2022). Majorana-like Coulomb spectroscopy in the absence of zero-bias peaks. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-022-05382-w\">https://doi.org/10.1038/s41586-022-05382-w</a>","ieee":"M. Valentini <i>et al.</i>, “Majorana-like Coulomb spectroscopy in the absence of zero-bias peaks,” <i>Nature</i>, vol. 612, no. 7940. Springer Nature, pp. 442–447, 2022.","ama":"Valentini M, Borovkov M, Prada E, et al. Majorana-like Coulomb spectroscopy in the absence of zero-bias peaks. <i>Nature</i>. 2022;612(7940):442-447. doi:<a href=\"https://doi.org/10.1038/s41586-022-05382-w\">10.1038/s41586-022-05382-w</a>","short":"M. Valentini, M. Borovkov, E. Prada, S. Martí-Sánchez, M. Botifoll, A.C. Hofmann, J. Arbiol, R. Aguado, P. San-Jose, G. Katsaros, Nature 612 (2022) 442–447."},"department":[{"_id":"GeKa"}],"volume":612,"main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2203.07829"}],"publisher":"Springer Nature","corr_author":"1","oa_version":"Preprint","keyword":["Multidisciplinary"],"related_material":{"link":[{"url":"https://ista.ac.at/en/news/imposter-particles-revealed-and-explained/","description":"News on ISTA Website","relation":"press_release"}],"record":[{"id":"12522","relation":"research_data","status":"public"},{"relation":"dissertation_contains","id":"13286","status":"public"}]},"date_updated":"2026-04-07T13:27:22Z","page":"442-447","author":[{"first_name":"Marco","last_name":"Valentini","full_name":"Valentini, Marco","id":"C0BB2FAC-D767-11E9-B658-BC13E6697425"},{"first_name":"Maksim","id":"2ac7a0a2-3562-11eb-9256-fbd18ea55087","last_name":"Borovkov","full_name":"Borovkov, Maksim"},{"first_name":"Elsa","full_name":"Prada, Elsa","last_name":"Prada"},{"last_name":"Martí-Sánchez","full_name":"Martí-Sánchez, Sara","first_name":"Sara"},{"last_name":"Botifoll","full_name":"Botifoll, Marc","first_name":"Marc"},{"first_name":"Andrea C","full_name":"Hofmann, Andrea C","last_name":"Hofmann","id":"340F461A-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jordi","full_name":"Arbiol, Jordi","last_name":"Arbiol"},{"first_name":"Ramón","last_name":"Aguado","full_name":"Aguado, Ramón"},{"full_name":"San-Jose, Pablo","last_name":"San-Jose","first_name":"Pablo"},{"first_name":"Georgios","full_name":"Katsaros, Georgios","last_name":"Katsaros","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8342-202X"}],"title":"Majorana-like Coulomb spectroscopy in the absence of zero-bias peaks","article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","intvolume":"       612","date_published":"2022-12-15T00:00:00Z","doi":"10.1038/s41586-022-05382-w","day":"15","oa":1,"ec_funded":1,"publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"year":"2022","acknowledgement":"We thank P. Krogstrup for providing us with the NW materials. We thank A. Higginbotham, E. J. H. Lee, C. Marcus and S. Vaitiekėnas for helpful discussions and G. Steffensen for his input on the diffusive Little-Parks theory. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the nanofabrication facility; the NOMIS Foundation; the CSIC Interdisciplinary Thematic Platform (PTI+) on Quantum Technologies (PTI-QTEP+). A.H. acknowledges support from H2020-MSCA-IF-2018/844511. ICN2 also acknowledges funding from Generalitat de Catalunya 2017 SGR 327. ICN2 is supported by the Severo Ochoa Program from Spanish MINECO (Grant no. SEV-2017-0706) and is funded by the CERCA Programme/Generalitat de Catalunya. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science PhD programme. Authors acknowledge the use of instrumentation as well as the technical advice provided by the National Facility ELECMI ICTS, node ‘Laboratorio de Microscopías Avanzadas’ at University of Zaragoza. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement no. 823717-ESTEEM3. This study was supported by MCIN with funding from European Union NextGenerationEU (PRTR-C17.I1) and Generalitat de Catalunya. This research is part of the CSIC programme for the Spanish Recovery, Transformation and Resilience Plan funded by the Recovery and Resilience Facility of the European Union, established by the Regulation (EU) 2020/2094. We thank support from Grant PGC2018-097018-BI00, project FlagERA TOPOGRAPH (PCI2018-093026) and project NANOGEN (PID2020-116093RB-C43), funded by MCIN/AEI/10.13039/501100011033/ and by ‘ERDF A way of making Europe’, by the European Union. M. Botifoll acknowledges support from SUR Generalitat de Catalunya and the EU Social Fund (project ref. 2020 FI 00103).","article_type":"original","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"publication":"Nature","arxiv":1,"isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"H2020","_id":"26A151DA-B435-11E9-9278-68D0E5697425","name":"Majorana bound states in Ge/SiGe heterostructures","grant_number":"844511"}]}]