---
_id: '13429'
abstract:
- lang: eng
  text: 'The fruitful core: Organic syntheses reported in the literature from 1850
    to 2004 are analyzed with mathematical tools from network theory and statistical
    physics. There is a set of substances (the core) from which the majority of other
    organic compounds can be made (see picture; red: core, blue: periphery, green:
    islands). Search algorithms are used to identify small optimal sets of maximally
    useful chemicals.'
article_processing_charge: No
article_type: original
author:
- first_name: Kyle J. M.
  full_name: Bishop, Kyle J. M.
  last_name: Bishop
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
- first_name: Bartosz A.
  full_name: Grzybowski, Bartosz A.
  last_name: Grzybowski
citation:
  ama: Bishop KJM, Klajn R, Grzybowski BA. The core and most useful molecules in organic
    chemistry. <i>Angewandte Chemie International Edition</i>. 2006;45(32):5348-5354.
    doi:<a href="https://doi.org/10.1002/anie.200600881">10.1002/anie.200600881</a>
  apa: Bishop, K. J. M., Klajn, R., &#38; Grzybowski, B. A. (2006). The core and most
    useful molecules in organic chemistry. <i>Angewandte Chemie International Edition</i>.
    Wiley. <a href="https://doi.org/10.1002/anie.200600881">https://doi.org/10.1002/anie.200600881</a>
  chicago: Bishop, Kyle J. M., Rafal Klajn, and Bartosz A. Grzybowski. “The Core and
    Most Useful Molecules in Organic Chemistry.” <i>Angewandte Chemie International
    Edition</i>. Wiley, 2006. <a href="https://doi.org/10.1002/anie.200600881">https://doi.org/10.1002/anie.200600881</a>.
  ieee: K. J. M. Bishop, R. Klajn, and B. A. Grzybowski, “The core and most useful
    molecules in organic chemistry,” <i>Angewandte Chemie International Edition</i>,
    vol. 45, no. 32. Wiley, pp. 5348–5354, 2006.
  ista: Bishop KJM, Klajn R, Grzybowski BA. 2006. The core and most useful molecules
    in organic chemistry. Angewandte Chemie International Edition. 45(32), 5348–5354.
  mla: Bishop, Kyle J. M., et al. “The Core and Most Useful Molecules in Organic Chemistry.”
    <i>Angewandte Chemie International Edition</i>, vol. 45, no. 32, Wiley, 2006,
    pp. 5348–54, doi:<a href="https://doi.org/10.1002/anie.200600881">10.1002/anie.200600881</a>.
  short: K.J.M. Bishop, R. Klajn, B.A. Grzybowski, Angewandte Chemie International
    Edition 45 (2006) 5348–5354.
date_created: 2023-08-01T10:37:16Z
date_published: 2006-08-11T00:00:00Z
date_updated: 2023-08-08T11:31:27Z
day: '11'
doi: 10.1002/anie.200600881
extern: '1'
external_id:
  pmid:
  - '16835857'
intvolume: '        45'
issue: '32'
keyword:
- General Chemistry
- Catalysis
language:
- iso: eng
month: '08'
oa_version: None
page: 5348-5354
pmid: 1
publication: Angewandte Chemie International Edition
publication_identifier:
  eissn:
  - 1521-3773
  issn:
  - 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: The core and most useful molecules in organic chemistry
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2006'
...
---
_id: '8488'
abstract:
- lang: eng
  text: We demonstrate for different protein samples that three-dimensional HNCO and
    HNCA correlation spectra may be recorded in a few minutes acquisition time using
    the band-selective excitation short-transient sequences presented here. This opens
    new perspectives for the NMR structural investigation of unstable protein samples
    and real-time site-resolved studies of protein kinetics.
article_processing_charge: No
article_type: original
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Hélène
  full_name: Van Melckebeke, Hélène
  last_name: Van Melckebeke
- first_name: Bernhard
  full_name: Brutscher, Bernhard
  last_name: Brutscher
citation:
  ama: Schanda P, Van Melckebeke H, Brutscher B. Speeding up three-dimensional protein
    NMR experiments to a few minutes. <i>Journal of the American Chemical Society</i>.
    2006;128(28):9042-9043. doi:<a href="https://doi.org/10.1021/ja062025p">10.1021/ja062025p</a>
  apa: Schanda, P., Van Melckebeke, H., &#38; Brutscher, B. (2006). Speeding up three-dimensional
    protein NMR experiments to a few minutes. <i>Journal of the American Chemical
    Society</i>. American Chemical Society. <a href="https://doi.org/10.1021/ja062025p">https://doi.org/10.1021/ja062025p</a>
  chicago: Schanda, Paul, Hélène Van Melckebeke, and Bernhard Brutscher. “Speeding
    up Three-Dimensional Protein NMR Experiments to a Few Minutes.” <i>Journal of
    the American Chemical Society</i>. American Chemical Society, 2006. <a href="https://doi.org/10.1021/ja062025p">https://doi.org/10.1021/ja062025p</a>.
  ieee: P. Schanda, H. Van Melckebeke, and B. Brutscher, “Speeding up three-dimensional
    protein NMR experiments to a few minutes,” <i>Journal of the American Chemical
    Society</i>, vol. 128, no. 28. American Chemical Society, pp. 9042–9043, 2006.
  ista: Schanda P, Van Melckebeke H, Brutscher B. 2006. Speeding up three-dimensional
    protein NMR experiments to a few minutes. Journal of the American Chemical Society.
    128(28), 9042–9043.
  mla: Schanda, Paul, et al. “Speeding up Three-Dimensional Protein NMR Experiments
    to a Few Minutes.” <i>Journal of the American Chemical Society</i>, vol. 128,
    no. 28, American Chemical Society, 2006, pp. 9042–43, doi:<a href="https://doi.org/10.1021/ja062025p">10.1021/ja062025p</a>.
  short: P. Schanda, H. Van Melckebeke, B. Brutscher, Journal of the American Chemical
    Society 128 (2006) 9042–9043.
date_created: 2020-09-18T10:13:36Z
date_published: 2006-06-21T00:00:00Z
date_updated: 2021-01-12T08:19:37Z
day: '21'
doi: 10.1021/ja062025p
extern: '1'
intvolume: '       128'
issue: '28'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
month: '06'
oa_version: None
page: 9042-9043
publication: Journal of the American Chemical Society
publication_identifier:
  issn:
  - 0002-7863
  - 1520-5126
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Speeding up three-dimensional protein NMR experiments to a few minutes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2006'
...
---
_id: '8492'
abstract:
- lang: eng
  text: We demonstrate for different protein samples that 2D 1H−15N correlation NMR
    spectra can be recorded in a few seconds of acquisition time using a new band-selective
    optimized flip-angle short-transient heteronuclear multiple quantum coherence
    experiment. This has enabled us to measure fast hydrogen−deuterium exchange rate
    constants along the backbone of a small globular protein fragment by real-time
    2D NMR.
article_processing_charge: No
article_type: original
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Bernhard
  full_name: Brutscher, Bernhard
  last_name: Brutscher
citation:
  ama: Schanda P, Brutscher B. Very fast two-dimensional NMR spectroscopy for real-time
    investigation of dynamic events in proteins on the time scale of seconds. <i>Journal
    of the American Chemical Society</i>. 2005;127(22):8014-8015. doi:<a href="https://doi.org/10.1021/ja051306e">10.1021/ja051306e</a>
  apa: Schanda, P., &#38; Brutscher, B. (2005). Very fast two-dimensional NMR spectroscopy
    for real-time investigation of dynamic events in proteins on the time scale of
    seconds. <i>Journal of the American Chemical Society</i>. American Chemical Society.
    <a href="https://doi.org/10.1021/ja051306e">https://doi.org/10.1021/ja051306e</a>
  chicago: Schanda, Paul, and Bernhard Brutscher. “Very Fast Two-Dimensional NMR Spectroscopy
    for Real-Time Investigation of Dynamic Events in Proteins on the Time Scale of
    Seconds.” <i>Journal of the American Chemical Society</i>. American Chemical Society,
    2005. <a href="https://doi.org/10.1021/ja051306e">https://doi.org/10.1021/ja051306e</a>.
  ieee: P. Schanda and B. Brutscher, “Very fast two-dimensional NMR spectroscopy for
    real-time investigation of dynamic events in proteins on the time scale of seconds,”
    <i>Journal of the American Chemical Society</i>, vol. 127, no. 22. American Chemical
    Society, pp. 8014–8015, 2005.
  ista: Schanda P, Brutscher B. 2005. Very fast two-dimensional NMR spectroscopy for
    real-time investigation of dynamic events in proteins on the time scale of seconds.
    Journal of the American Chemical Society. 127(22), 8014–8015.
  mla: Schanda, Paul, and Bernhard Brutscher. “Very Fast Two-Dimensional NMR Spectroscopy
    for Real-Time Investigation of Dynamic Events in Proteins on the Time Scale of
    Seconds.” <i>Journal of the American Chemical Society</i>, vol. 127, no. 22, American
    Chemical Society, 2005, pp. 8014–15, doi:<a href="https://doi.org/10.1021/ja051306e">10.1021/ja051306e</a>.
  short: P. Schanda, B. Brutscher, Journal of the American Chemical Society 127 (2005)
    8014–8015.
date_created: 2020-09-18T10:14:05Z
date_published: 2005-05-14T00:00:00Z
date_updated: 2021-01-12T08:19:39Z
day: '14'
doi: 10.1021/ja051306e
extern: '1'
intvolume: '       127'
issue: '22'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
month: '05'
oa_version: None
page: 8014-8015
publication: Journal of the American Chemical Society
publication_identifier:
  issn:
  - 0002-7863
  - 1520-5126
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic
  events in proteins on the time scale of seconds
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 127
year: '2005'
...
---
_id: '13435'
abstract:
- lang: eng
  text: Micropatterning of surfaces with several chemicals at different spatial locations
    usually requires multiple stamping and registration steps. Here, we describe an
    experimental method based on reaction–diffusion phenomena that allows for simultaneous
    micropatterning of a substrate with several coloured chemicals. In this method,
    called wet stamping (WETS), aqueous solutions of two or more inorganic salts are
    delivered onto a film of dry, ionically doped gelatin from an agarose stamp patterned
    in bas relief. Once in conformal contact, these salts diffuse into the gelatin,
    where they react to give deeply coloured precipitates. Separation of colours in
    the plane of the surface is the consequence of the differences in the diffusion
    coefficients, the solubility products, and the amounts of different salts delivered
    from the stamp, and is faithfully reproduced by a theoretical model based on a
    system of reaction–diffusion partial differential equations. The multicolour micropatterns
    are useful as non-binary optical elements, and could potentially form the basis
    of new applications in microseparations and in controlled delivery.
article_processing_charge: No
article_type: original
author:
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
- first_name: Marcin
  full_name: Fialkowski, Marcin
  last_name: Fialkowski
- first_name: Igor T.
  full_name: Bensemann, Igor T.
  last_name: Bensemann
- first_name: Agnieszka
  full_name: Bitner, Agnieszka
  last_name: Bitner
- first_name: C. J.
  full_name: Campbell, C. J.
  last_name: Campbell
- first_name: Kyle
  full_name: Bishop, Kyle
  last_name: Bishop
- first_name: Stoyan
  full_name: Smoukov, Stoyan
  last_name: Smoukov
- first_name: Bartosz A.
  full_name: Grzybowski, Bartosz A.
  last_name: Grzybowski
citation:
  ama: Klajn R, Fialkowski M, Bensemann IT, et al. Multicolour micropatterning of
    thin films of dry gels. <i>Nature Materials</i>. 2004;3:729-735. doi:<a href="https://doi.org/10.1038/nmat1231">10.1038/nmat1231</a>
  apa: Klajn, R., Fialkowski, M., Bensemann, I. T., Bitner, A., Campbell, C. J., Bishop,
    K., … Grzybowski, B. A. (2004). Multicolour micropatterning of thin films of dry
    gels. <i>Nature Materials</i>. Springer Nature. <a href="https://doi.org/10.1038/nmat1231">https://doi.org/10.1038/nmat1231</a>
  chicago: Klajn, Rafal, Marcin Fialkowski, Igor T. Bensemann, Agnieszka Bitner, C.
    J. Campbell, Kyle Bishop, Stoyan Smoukov, and Bartosz A. Grzybowski. “Multicolour
    Micropatterning of Thin Films of Dry Gels.” <i>Nature Materials</i>. Springer
    Nature, 2004. <a href="https://doi.org/10.1038/nmat1231">https://doi.org/10.1038/nmat1231</a>.
  ieee: R. Klajn <i>et al.</i>, “Multicolour micropatterning of thin films of dry
    gels,” <i>Nature Materials</i>, vol. 3. Springer Nature, pp. 729–735, 2004.
  ista: Klajn R, Fialkowski M, Bensemann IT, Bitner A, Campbell CJ, Bishop K, Smoukov
    S, Grzybowski BA. 2004. Multicolour micropatterning of thin films of dry gels.
    Nature Materials. 3, 729–735.
  mla: Klajn, Rafal, et al. “Multicolour Micropatterning of Thin Films of Dry Gels.”
    <i>Nature Materials</i>, vol. 3, Springer Nature, 2004, pp. 729–35, doi:<a href="https://doi.org/10.1038/nmat1231">10.1038/nmat1231</a>.
  short: R. Klajn, M. Fialkowski, I.T. Bensemann, A. Bitner, C.J. Campbell, K. Bishop,
    S. Smoukov, B.A. Grzybowski, Nature Materials 3 (2004) 729–735.
date_created: 2023-08-01T10:39:23Z
date_published: 2004-09-19T00:00:00Z
date_updated: 2023-08-08T12:42:51Z
day: '19'
doi: 10.1038/nmat1231
extern: '1'
external_id:
  pmid:
  - '15378052'
intvolume: '         3'
keyword:
- Mechanical Engineering
- Mechanics of Materials
- Condensed Matter Physics
- General Materials Science
- General Chemistry
language:
- iso: eng
month: '09'
oa_version: None
page: 729-735
pmid: 1
publication: Nature Materials
publication_identifier:
  eissn:
  - 1476-4660
  issn:
  - 1476-1122
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multicolour micropatterning of thin films of dry gels
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2004'
...